acetaminophen and carbamazepine

acetaminophen has been researched along with carbamazepine in 106 studies

Research

Studies (106)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (8.49)	18.7374
1990's	4 (3.77)	18.2507
2000's	32 (30.19)	29.6817
2010's	49 (46.23)	24.3611
2020's	12 (11.32)	2.80

Authors

Authors	Studies
Strassburg, CP; Tukey, RH	1
Topliss, JG; Yoshida, F	1
Abraham, MH; Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Faassen, F; Spanings, H; Vogel, G; Vromans, H	1
Chang, TK; Ensom, MH; Kiang, TK	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Botta, M; Dreassi, E; Falchi, F; Maga, G; Santucci, A; Schenone, S; Zizzari, AT	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Avdeef, A; Tam, KY	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Ekins, S; Williams, AJ; Xu, JJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A	1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bharate, SS; Vishwakarma, RA	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Borges, F; Chavarria, D; Fernandes, C; Gil-Martins, E; Oliveira, PJ; Remião, F; Silva, C; Silva, R; Silva, T; Silva, V; Soares, P	1
Richens, A	1
Dusci, LJ; Hackett, LP	1
Rollin, H	1
Perucca, E; Richens, A	1
Parkhouse, J	1
Beck, P; Hine, ID; Routledge, PA; Smith, JA	1
Miller, M; Moses, AM	1
Trautmann, A	1
D'Arcy, PF	1
Anderson, PJ; Critchley, JA; Kay, R; Ng, MC; Tomlinson, B; Young, RP	1
Abbott, FS; Farrell, K; Tabatabaei, AR; Thies, RL	1
Chan, TY	2
Mazure, CM; Young, CR	1
Doughty, SW; Grimsey, IM; Osborn, JC; Rowe, RC; Sunkersett, MR; York, P	1
Law, D; Qiu, Y; Schmitt, EA; Zhang, GG	1
Dillon, LC; Parikh, S; Scharf, SL	1
Brain, RA; Hanson, ML; Johnson, DJ; Lam, MW; Mabury, SA; Richards, SM; Sanderson, H; Sibley, PK; Solomon, KR; Young, C	1
Aboo, A; Adams, BK; Evans, A; Isaacs, S; Mann, MD	1
Grzesiak, AL; Matzger, AJ; Price, CP	1
Hari, AC; Kibbey, TC; Paruchuri, RA; Sabatini, DA	1
Mannerström, M; Tähti, H; Toimela, T; Ylikomi, T	1
Choi, K; Jung, J; Kim, PG; Kim, Y; Park, J; Park, S	1
Humphreys, WG; Ma, L; Olah, T; Xin, B; Zheng, J; Zhu, M	1
Chappell, AS; D'Souza, DN; Iyengar, S; Pritchett, YL; Raskin, J; Smith, TR; Wang, F; Wernicke, JF	1
Humphreys, WG; Ma, L; Zhang, H; Zhu, M	1
Ma, L; Ruan, Q; Wen, B; Zhu, M	1
Kalgutkar, AS; Obach, RS; Soglia, JR; Zhao, SX	1
Fitch, WL; Wen, B	1
Chang, CJ; Chao, PF; Gau, CS; Gau, SS; Lin, YJ	1
Goldfarb, DS; Hoffman, RS; Holubek, WJ; Nelson, LS	1
Ahmed, SN; Heino, A; Jickling, G	1
Alonso, E; Aparicio, I; Bron, JE; Hampel, M; Leaver, MJ; Santos, JL; Taggart, JB	1
Bosković, B; Prostran, MS; Stepanović-Petrović, RM; Tomić, MA; Ugresić, ND; Vucković, SM	1
Honma, M; Iinuma, S; Iizuka, H; Ishida-Yamamoto, A; Komatsu, S; Shibuya, T; Takahashi, I; Tobisawa, S	1
Dansette, PM; Defoy, D; Klarskov, K; Neugebauer, W; Wagner, JR	1
Bleumink, R; Boon, L; Fiechter, D; Hassing, I; Kwast, LM; Ludwig, IS; Pieters, RH	1
Arizono, K; Matsuo, H; Sakamoto, H; Shinohara, R	1
Cren-Olivé, C; Vulliet, E	1
Kühne, S; Steinert, M; Untucht, C; Wätzig, H	1
Borza, A; Ordodi, V; Vaszilcsin, N	1
Chen, F; Chen, H; Fu, W; Luo, W; Meng, F; Xie, Y; Yang, X; Ye, T; Young, K	1
Ahmad, F; Mansoor, B; Zaib, Q	1
Jeong, CB; Kim, BM; Lee, JS; Lee, YM; Leung, KM; Park, HG; Rhee, JS	1
Šakić, D; Šonjić, P; Tandarić, T; Vrček, V	1
Licha, T; Nödler, K; Tsakiri, M	1
Alhussainy, TM; Arafat, TA; Idkaidek, NM; Ismail, OA; Qinna, NA	1
Barcellini-Couget, S; de Sousa, G; Luzy, AP; Peyre, L; Rahmani, R; Zucchini-Pascal, N	1
Aouam, K; Ben Fredj, N; Boughattas, NA; Chaabane, A; Chadli, Z; Youssef, M; Zili, JE	1
Cimetière, N; Fallou, H; Giraudet, S; Le Cloirec, P; Wolbert, D	1
Bleumink, R; Bol-Schoenmakers, M; Fiechter, D; Kruijssen, L; Kwast, L; Ludwig, I; Pieters, R; Smit, J	1
de Bustamante, I; Herrera López, S; Martínez-Hernández, V; Meffe, R	1
Blasco, J; Hampel, M; Trombini, C	1
Bojunga, N; Lesko, LJ; Schotland, P; Trame, MN; Zien, A	1
Azaïs, A; Brosillon, S; Mendret, J; Petit, E	1
Benskin, JP; Butler, H; Chandramouli, B; Cosgrove, JR; Helbing, CC; Huang, SSY; Veldhoen, N	1
Drewes, JE; Graßmann, J; Letzel, T; Stadlmair, LF	1
de Bustamante, I; Kohfahl, C; Martínez-Hernández, V; Meffe, R	1
Baamonde, A; Brid, T; González, N; Sacristán de Lama, MP	1
Babbucci, M; Bargelloni, L; Blasco, J; Ferraresso, S; Hampel, M; Milan, M	1
Azaïs, A; Brosillon, S; Cazals, G; Mendret, J; Petit, E	1
Amat, AM; Arques, A; Gomis, J; Marin, ML; Martinez-Haya, R; Miranda, MA	1
Baekelandt, S; Beghin, M; Gillet, M; Kestemont, P; Mandiki, SNM; Nott, K; Robert, C; Ronkart, S; Schmitz, M	1
Avau, B; Borra, V; De Buck, E; De Paepe, P; Vandekerckhove, P; Vanhove, AC	1
Davison, SN	1
Nakamura, R; Saito, Y	1
Flanagan, T; Fotaki, N; Mann, J; Meehan, E; Zarmpi, P	1
Belmonte, PRH; Cardoso, CSG; da Silva, JCGE; Mota, AAR; Oliveira, MACG; Santos, AJM	1
Bado-Nilles, A; Beaudouin, R; Castiglione, J; Catteau, A; Chadili, E; David, V; Dedourge-Geffard, O; Geffard, A; Gillard, N; Hani, Y; Joachim, S; Julian, N; Nott, K; Palluel, O; Porcher, JM; Robert, C; Ronkart, S; Turies, C	1
Beobide Telleria, I; Ferro Uriguen, A; Martínez Arrechea, S; Miró Isasi, B; Sampedro Yangüela, C; Urretavizcaya Anton, M	1
Baekelandt, S; Beghin, M; Betoulle, S; Gillet, E; Kestemont, P; Mandiki, SNM; Nott, K; Palluel, O; Porcher, JM; Robert, C; Ronkart, S; Schmitz, M	1
Correia, AT; Guimarães, LL; Roveri, V; Toma, W	2
Correia, AT; de Oliveira, TMN; Guimarães, LL; Pisetta, AM; Roveri, V	1
Alsubih, M; Balakrishnan, D; El Morabet, R; Khan, AR; Khan, NA; Khan, RA; Khan, S; Khoo, KS; Mubashir, M	1
Gálvez-Rodríguez, A; Kumar, M; Mohapatra, S; Mukherji, S; Padhye, LP; Shea, P; Snow, D	1
Masís-Mora, M; Méndez-Rivera, M; Montiel-Mora, JR; Ramírez-Morales, D; Rodríguez-Rodríguez, CE	1

Reviews

10 review(s) available for acetaminophen and carbamazepine

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacology & therapeutics, 2005, Volume: 106, Issue:1 Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic	2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Interactions with antiepileptic drugs. Drugs, 1977, Volume: 13, Issue:4 Topics: Acetaminophen; Acetazolamide; Anti-Anxiety Agents; Anticoagulants; Anticonvulsants; Carbamazepine; Diazepam; Drug Interactions; Furosemide; Gonadal Steroid Hormones; Griseofulvin; Humans; Phenobarbital; Phenytoin; Primidone; Thiazines; Urea; Valproic Acid; Vitamin D	1977
Simple analgesics. Drugs, 1975, Volume: 10, Issue:5-6 Topics: Acetaminophen; Analgesics; Aspirin; Azepines; Carbamazepine; Codeine; Dextropropoxyphene; Drug Combinations; Flufenamic Acid; Humans; Mefenamic Acid; Pain; Phenacetin	1975
Drug-induced dilutional hyponatremia. The New England journal of medicine, 1974, Dec-05, Volume: 291, Issue:23 Topics: Acetaminophen; Amitriptyline; Animals; Anura; Body Fluids; Carbamazepine; Chlorpropamide; Clofibrate; Cyclophosphamide; Diabetes Insipidus; Diabetes Mellitus; Diazoxide; Drug-Related Side Effects and Adverse Reactions; Humans; Hypoglycemic Agents; Hyponatremia; Kidney; Rats; Sodium; Sulfonylurea Compounds; Tolbutamide; Urinary Bladder; Vasopressins; Vincristine; Water Intoxication; Water-Electrolyte Balance	1974
Packaging of drugs and the risk of severe toxicity in adult self-poisonings. Journal of clinical pharmacy and therapeutics, 1997, Volume: 22, Issue:3 Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Carbamazepine; Drug Overdose; Drug Packaging; Hong Kong; Humans; Self Administration; United Kingdom	1997
Phase transformation considerations during process development and manufacture of solid oral dosage forms. Advanced drug delivery reviews, 2004, Feb-23, Volume: 56, Issue:3 Topics: Acetaminophen; Administration, Oral; Aspirin; Capsules; Carbamazepine; Chemistry Techniques, Analytical; Crystallization; Drug Compounding; Drug Stability; Excipients; Freeze Drying; Humans; Particle Size; Pharmaceutical Preparations; Phase Transition; Ritonavir; Solvents; Tablets; Technology, Pharmaceutical; Theophylline; Thermodynamics; Thiamine; Transition Temperature; Water	2004
First aid interventions by laypeople for acute oral poisoning. The Cochrane database of systematic reviews, 2018, 12-19, Volume: 12 Topics: Acetaminophen; Analgesics, Non-Narcotic; Antidepressive Agents; Antidotes; Benzodiazepines; Carbamazepine; Cathartics; Charcoal; First Aid; Fruit; Humans; Ipecac; Poisoning; Publication Bias; Randomized Controlled Trials as Topic; Thevetia	2018
[Mechanisms of Severe Cutaneous Adverse Reactions and a New Treatment Strategy]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2019, Volume: 139, Issue:12 Topics: Acetaminophen; Adrenal Cortex Hormones; Allopurinol; Antigens, Differentiation, T-Lymphocyte; Carbamazepine; CD8-Positive T-Lymphocytes; Cyclosporine; Epidermis; Etanercept; Fas Ligand Protein; HLA Antigens; Humans; Immunoglobulins, Intravenous; Immunosuppressive Agents; Japan; Lamotrigine; Plasma Exchange; Stevens-Johnson Syndrome; Tumor Necrosis Factor-alpha	2019

Trials

2 trial(s) available for acetaminophen and carbamazepine

Article	Year
Paracetamol disposition in normal subjects and in patients treated with antiepileptic drugs. British journal of clinical pharmacology, 1979, Volume: 7, Issue:2 Topics: Acetaminophen; Administration, Oral; Adult; Anticonvulsants; Biological Availability; Carbamazepine; Female; Humans; Injections, Intravenous; Male; Phenobarbital; Phenytoin; Primidone	1979
An open-label 52-week clinical extension comparing duloxetine with routine care in patients with diabetic peripheral neuropathic pain. Pain medicine (Malden, Mass.), 2007, Volume: 8, Issue:6 Topics: Acetaminophen; Amitriptyline; Analgesics; Carbamazepine; Diabetes Complications; Diabetic Neuropathies; Diclofenac; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Lipids; Male; Meloxicam; Middle Aged; Neuralgia; Pentoxifylline; Selective Serotonin Reuptake Inhibitors; Thiamine; Thiazines; Thiazoles; Thioctic Acid; Thiophenes; Time; Vitamin B 12	2007

Article

Year

Paracetamol disposition in normal subjects and in patients treated with antiepileptic drugs.

British journal of clinical pharmacology, 1979, Volume: 7, Issue:2

Topics: Acetaminophen; Administration, Oral; Adult; Anticonvulsants; Biological Availability; Carbamazepine; Female; Humans; Injections, Intravenous; Male; Phenobarbital; Phenytoin; Primidone

1979

An open-label 52-week clinical extension comparing duloxetine with routine care in patients with diabetic peripheral neuropathic pain.

Pain medicine (Malden, Mass.), 2007, Volume: 8, Issue:6

Topics: Acetaminophen; Amitriptyline; Analgesics; Carbamazepine; Diabetes Complications; Diabetic Neuropathies; Diclofenac; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Lipids; Male; Meloxicam; Middle Aged; Neuralgia; Pentoxifylline; Selective Serotonin Reuptake Inhibitors; Thiamine; Thiazines; Thiazoles; Thioctic Acid; Thiophenes; Time; Vitamin B 12

2007

Other Studies

94 other study(ies) available for acetaminophen and carbamazepine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
ElogPoct: a tool for lipophilicity determination in drug discovery. Journal of medicinal chemistry, 2000, Jul-27, Volume: 43, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Solvents	2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Caco-2 permeability, P-glycoprotein transport ratios and brain penetration of heterocyclic drugs. International journal of pharmaceutics, 2003, Sep-16, Volume: 263, Issue:1-2 Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Caco-2 Cells; Cell Membrane Permeability; Heterocyclic Compounds; Humans; Protein Transport	2003
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Determination of permeability and lipophilicity of pyrazolo-pyrimidine tyrosine kinase inhibitors and correlation with biological data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:9 Topics: Humans; Lipids; Membranes, Artificial; Permeability; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-abl; Pyrazoles; Pyrimidines	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability? Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9 Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7 Topics: Glutathione; Pharmacology; Sulfur Radioisotopes	2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1 Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery. Bioorganic & medicinal chemistry letters, 2015, Apr-01, Volume: 25, Issue:7 Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics	2015
Design of novel monoamine oxidase-B inhibitors based on piperine scaffold: Structure-activity-toxicity, drug-likeness and efflux transport studies. European journal of medicinal chemistry, 2020, Jan-01, Volume: 185 Topics: Alkaloids; Benzodioxoles; Caco-2 Cells; Cell Differentiation; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Humans; Ligands; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Oxidative Stress; Piperidines; Polyunsaturated Alkamides; Structure-Activity Relationship; Tumor Cells, Cultured	2020
High performance liquid chromatography in clinical toxicology. I. General drugs. Clinical toxicology, 1978, Volume: 13, Issue:5 Topics: Acetaminophen; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Indomethacin; Pharmaceutical Preparations; Theophylline; Thiazines; Toxicology	1978
[Gustatory disturbances as sideeffect of medical treatment (author's transl)]. Laryngologie, Rhinologie, Otologie, 1976, Volume: 55, Issue:11 Topics: Acetaminophen; Adult; Ageusia; Back Pain; Carbamazepine; Chlormezanone; Dysgeusia; Female; Humans; Male; Middle Aged; Oxyfedrine; Phenylbutazone; Taste Disorders; Trigeminal Neuralgia	1976
Paracetamol toxicity: is enzyme induction important? Human toxicology, 1986, Volume: 5, Issue:6 Topics: Acetaminophen; Adolescent; Carbamazepine; Enzyme Induction; Female; Half-Life; Humans; Liver	1986
[Dialysis of drugs and poisons. 2]. Medizinische Klinik, 1972, Nov-03, Volume: 67, Issue:44 Topics: Acetaminophen; Aminopyrine; Amitriptyline; Aspirin; Carbamazepine; Chlordiazepoxide; Chlorpromazine; Dextropropoxyphene; Diazepam; Heroin; Humans; Imipramine; Lithium; Pargyline; Pentazocine; Phenacetin; Phenelzine; Phenytoin; Poisoning; Primidone; Promazine; Renal Dialysis; Salicylates; Tranylcypromine; Trifluoperazine	1972
Early reports on drug interactions. Drug intelligence & clinical pharmacy, 1983, Volume: 17, Issue:2 Topics: Acetaminophen; Amiodarone; Apazone; Aspirin; Carbamazepine; Chlordiazepoxide; Cimetidine; Coumarins; Drug Interactions; Erythromycin; Ethanol; Furosemide; Gentamicins; Humans; Levodopa; Lidocaine; Phenytoin; Prenylamine; Quinidine	1983
Selective liver enzyme induction by carbamazepine and phenytoin in Chinese epileptics. European journal of clinical pharmacology, 1996, Volume: 50, Issue:5 Topics: Acetaminophen; Adult; Anticonvulsants; Carbamazepine; China; Cytochrome P-450 Enzyme System; Enzyme Induction; Epilepsy, Tonic-Clonic; Female; Glucuronates; Humans; Hydrocortisone; Liver; Male; Phenytoin	1996
A rapid in vitro assay for evaluation of metabolism-dependent cytotoxicity of antiepileptic drugs on isolated human lymphocytes. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1997, Volume: 37, Issue:2 Topics: Acetaminophen; Animals; Anticonvulsants; Biological Assay; Carbamazepine; Cell Count; Cell Survival; Female; Fluorescence; Humans; In Vitro Techniques; Lymphocytes; Microsomes, Liver; Phenobarbital; Phenytoin; Rabbits	1997
Fulminant hepatic failure from acetaminophen in an anorexic patient treated with carbamazepine. The Journal of clinical psychiatry, 1998, Volume: 59, Issue:11 Topics: Acetaminophen; Adolescent; Anorexia Nervosa; Carbamazepine; Drug Overdose; Drug Synergism; Drug Therapy, Combination; Female; Humans; Liver Failure; Suicide, Attempted	1998
Improvements in the packaging of drugs and chemicals may reduce the likelihood of severe intentional poisonings in adults. Human & experimental toxicology, 2000, Volume: 19, Issue:7 Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Carbamazepine; Drug Packaging; Household Products; Humans; Poisoning; Salicylates; Suicide	2000
The changes in surface energetics with relative humidity of carbamazepine and paracetamol as measured by inverse gas chromatography. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2001, Volume: 13, Issue:2 Topics: Acetaminophen; Analgesics, Non-Narcotic; Carbamazepine; Chromatography, Gas; Humidity; Models, Molecular; Powders	2001
Hepatotoxicity possibly due to paracetamol with carbamazepine. Internal medicine journal, 2004, Volume: 34, Issue:7 Topics: Acetaminophen; Age Factors; Aged; Aged, 80 and over; Carbamazepine; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Risk Assessment; Severity of Illness Index	2004
Microcosm evaluation of the effects of an eight pharmaceutical mixture to the aquatic macrophytes Lemna gibba and Myriophyllum sibiricum. Aquatic toxicology (Amsterdam, Netherlands), 2004, Oct-18, Volume: 70, Issue:1 Topics: Acetaminophen; Analysis of Variance; Atorvastatin; Biological Assay; Biomass; Caffeine; Carbamazepine; Complex Mixtures; Dose-Response Relationship, Drug; Heptanoic Acids; Heterocyclic Compounds; Levofloxacin; Magnoliopsida; Ofloxacin; Pharmaceutical Solutions; Pyrroles; Sertraline; Sulfamethoxazole; Toxicity Tests; Trimethoprim; Water Pollutants, Chemical	2004
Prolonged gastric emptying half-time and gastric hypomotility after drug overdose. The American journal of emergency medicine, 2004, Volume: 22, Issue:7 Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents, Tricyclic; Carbamazepine; Central Nervous System Agents; Colloids; Drug Overdose; Female; Follow-Up Studies; Gastric Emptying; Gastrointestinal Motility; Humans; Male; Middle Aged; Phenytoin; Prospective Studies; Radionuclide Imaging; Radiopharmaceuticals; Stomach; Technetium Compounds; Tin Compounds	2004
Crystalline polymorph selection and discovery with polymer heteronuclei. Journal of the American Chemical Society, 2005, Apr-20, Volume: 127, Issue:15 Topics: Acetaminophen; Carbamazepine; Chemistry, Pharmaceutical; Crystallization; Models, Molecular; Polymers; Spectrum Analysis, Raman; Sulfamethoxazole; Thiophenes; X-Ray Diffraction	2005
Effects of pH and cationic and nonionic surfactants on the adsorption of pharmaceuticals to a natural aquifer material. Environmental science & technology, 2005, Apr-15, Volume: 39, Issue:8 Topics: Acetaminophen; Adsorption; Carbamazepine; Cations; Cetylpyridinium; Environmental Monitoring; Geologic Sediments; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Nalidixic Acid; Norfloxacin; Pharmaceutical Preparations; Poloxalene; Surface-Active Agents; Water Pollution, Chemical	2005
The combined use of human neural and liver cell lines and mouse hepatocytes improves the predictability of the neurotoxicity of selected drugs. Toxicology letters, 2006, Aug-20, Volume: 165, Issue:2 Topics: Acetaminophen; Adenosine Triphosphate; Amitriptyline; Animal Testing Alternatives; Animals; Carbamazepine; Cell Line, Tumor; Cell Survival; Central Nervous System Agents; Dose-Response Relationship, Drug; Hepatocytes; Humans; Mice; Neurons; Predictive Value of Tests; Reproducibility of Results; Selegiline; Toxicity Tests	2006
Aquatic toxicity of acetaminophen, carbamazepine, cimetidine, diltiazem and six major sulfonamides, and their potential ecological risks in Korea. Environment international, 2007, Volume: 33, Issue:3 Topics: Acetaminophen; Aliivibrio fischeri; Analgesics, Non-Narcotic; Animals; Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Carbamazepine; Cimetidine; Daphnia; Diltiazem; Environmental Monitoring; Histamine H2 Antagonists; Korea; Lethal Dose 50; Oryzias; Quantitative Structure-Activity Relationship; Risk Assessment; Sulfonamides; Water Pollutants, Chemical	2007
Screening and identification of GSH-trapped reactive metabolites using hybrid triple quadruple linear ion trap mass spectrometry. Chemical research in toxicology, 2007, Volume: 20, Issue:5 Topics: Acetaminophen; Carbamazepine; Chromatography, High Pressure Liquid; Diclofenac; Drug Evaluation, Preclinical; Glutathione; Humans; Microsomes, Liver; Pharmaceutical Preparations; Spectrometry, Mass, Electrospray Ionization	2007
Detection and structural characterization of glutathione-trapped reactive metabolites using liquid chromatography-high-resolution mass spectrometry and mass defect filtering. Analytical chemistry, 2007, Nov-01, Volume: 79, Issue:21 Topics: Acetaminophen; Animals; Bile; Carbamazepine; Chromatography, Liquid; Clozapine; Cresols; Diclofenac; Glutathione; Humans; Microsomes, Liver; Molecular Structure; Oxidation-Reduction; Phenols; Rats; Reproducibility of Results; Sensitivity and Specificity; Skatole; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Time Factors	2007
Rapid screening of glutathione-trapped reactive metabolites by linear ion trap mass spectrometry with isotope pattern-dependent scanning and postacquisition data mining. Chemical research in toxicology, 2008, Volume: 21, Issue:7 Topics: Acetaminophen; Carbamazepine; Cresols; Diclofenac; Drug Evaluation, Preclinical; Glutathione; Omeprazole; Pharmaceutical Preparations; Phenols; Predictive Value of Tests; Spectrometry, Mass, Electrospray Ionization	2008
Can in vitro metabolism-dependent covalent binding data in liver microsomes distinguish hepatotoxic from nonhepatotoxic drugs? An analysis of 18 drugs with consideration of intrinsic clearance and daily dose. Chemical research in toxicology, 2008, Volume: 21, Issue:9 Topics: Acetaminophen; Binding Sites; Buspirone; Carbamazepine; Diclofenac; Diphenhydramine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Hepatocytes; Humans; Indomethacin; Meloxicam; Microsomes, Liver; Molecular Structure; Paroxetine; Piperazines; Propranolol; Raloxifene Hydrochloride; Simvastatin; Structure-Activity Relationship; Thiazines; Thiazoles; Ticrynafen; Toxicity Tests; Triazoles	2008
Screening and characterization of reactive metabolites using glutathione ethyl ester in combination with Q-trap mass spectrometry. Journal of mass spectrometry : JMS, 2009, Volume: 44, Issue:1 Topics: Acetaminophen; Amodiaquine; Carbamazepine; Glutathione; Humans; Imipramine; Mass Spectrometry; Metabolomics; Microsomes, Liver; Phenols; Reproducibility of Results; Sensitivity and Specificity; Ticlopidine	2009
The association between carbamazepine and valproate and adverse cutaneous drug reactions in patients with bipolar disorder: a nested matched case-control study. Journal of clinical psychopharmacology, 2008, Volume: 28, Issue:5 Topics: Acetaminophen; Adult; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Case-Control Studies; Databases, Factual; Drug Eruptions; Drug Interactions; Erythema Multiforme; Female; Humans; Male; Middle Aged; Stevens-Johnson Syndrome; Valproic Acid	2008
Use of hemodialysis and hemoperfusion in poisoned patients. Kidney international, 2008, Volume: 74, Issue:10 Topics: Acetaminophen; Carbamazepine; Ethylene Glycol; Hemoperfusion; Humans; Lithium; Poisoning; Poisons; Renal Dialysis; Retrospective Studies; Sorption Detoxification; Valproic Acid	2008
Acetaminophen toxicity with concomitant use of carbamazepine. Epileptic disorders : international epilepsy journal with videotape, 2009, Volume: 11, Issue:4 Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anticonvulsants; Back Pain; Carbamazepine; Chemical and Drug Induced Liver Injury; Clonazepam; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Epilepsy, Complex Partial; Humans; Liver Function Tests; Male; Methocarbamol; Muscle Relaxants, Central; Nephritis, Interstitial; Neurologic Examination	2009
Potential physiological effects of pharmaceutical compounds in Atlantic salmon (Salmo salar) implied by transcriptomic analysis. Environmental science and pollution research international, 2010, Volume: 17, Issue:4 Topics: Acetaminophen; Animals; Atenolol; Carbamazepine; Environmental Monitoring; Fish Proteins; Gene Expression; Gene Expression Profiling; Male; RNA, Messenger; Salmo salar; Water Pollutants, Chemical	2010
Synergistic interactions between paracetamol and oxcarbazepine in somatic and visceral pain models in rodents. Anesthesia and analgesia, 2010, Apr-01, Volume: 110, Issue:4 Topics: Acetaminophen; Acetic Acid; Algorithms; Analgesics, Non-Narcotic; Animals; Anticonvulsants; Carbamazepine; Carrageenan; Dose-Response Relationship, Drug; Drug Synergism; Hyperalgesia; Male; Mice; Oxcarbazepine; Pain; Rats; Rats, Wistar	2010
Toxic epidermal necrolysis with prominent facial pustules: a case with reactivation of human herpesvirus 7. Dermatology (Basel, Switzerland), 2010, Volume: 221, Issue:4 Topics: Acetaminophen; Acute Generalized Exanthematous Pustulosis; Adult; Anti-Inflammatory Agents; Antidepressive Agents; Carbamazepine; Depression; Eosinophilia; Herpesvirus 7, Human; Humans; Male; Methylprednisolone; Roseolovirus Infections; Stevens-Johnson Syndrome; Treatment Outcome; Virus Activation	2010
Evaluation of deuterium labeled and unlabeled bis-methyl glutathione combined with nanoliquid chromatography-mass spectrometry to screen and characterize reactive drug metabolites. Chemical research in toxicology, 2011, Mar-21, Volume: 24, Issue:3 Topics: Acetaminophen; Animals; Carbamazepine; Chromatography, High Pressure Liquid; Deuterium; Deuterium Exchange Measurement; Esterification; Glutathione; Isotope Labeling; Male; Microsomes; NADP; Nanotechnology; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization	2011
Oral exposure to drugs with immune-adjuvant potential induces hypersensitivity responses to the reporter antigen TNP-OVA. Toxicological sciences : an official journal of the Society of Toxicology, 2011, Volume: 121, Issue:2 Topics: Acetaminophen; Acetanilides; Adjuvants, Immunologic; Administration, Oral; Animals; Antibody Formation; Carbamazepine; Drug Evaluation, Preclinical; Drug Hypersensitivity; Female; Injections, Epidural; Local Lymph Node Assay; Metformin; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Ofloxacin; Ovalbumin	2011
Behavior of pharmaceuticals in waste water treatment plant in Japan. Bulletin of environmental contamination and toxicology, 2011, Volume: 87, Issue:1 Topics: Acetaminophen; Amoxicillin; Ampicillin; Carbamazepine; Chromatography, Liquid; Diclofenac; Famotidine; Japan; Ketoprofen; Losartan; Mass Spectrometry; Oseltamivir; Sewage; Trimethoprim; Waste Disposal, Fluid; Water Pollutants, Chemical; Water Purification	2011
Screening of pharmaceuticals and hormones at the regional scale, in surface and groundwaters intended to human consumption. Environmental pollution (Barking, Essex : 1987), 2011, Volume: 159, Issue:10 Topics: Acetaminophen; Androstenedione; Carbamazepine; Environmental Exposure; Fresh Water; Groundwater; Hormones; Humans; Pharmaceutical Preparations; Progesterone; Risk Assessment; Salicylic Acid; Testosterone; Water Pollutants, Chemical; Water Supply	2011
Fast investigations from biological matrices using CE--test of a blood-brain barrier model. Electrophoresis, 2012, Volume: 33, Issue:2 Topics: Acetaminophen; Adsorption; Animals; Blood-Brain Barrier; Caffeine; Carbamazepine; Cell Culture Techniques; Cell Line; Chromatography, Micellar Electrokinetic Capillary; Cimetidine; Humans; Indomethacin; Limit of Detection; Models, Biological; Propranolol; Rats; Reproducibility of Results; Tissue Distribution	2012
Corrosion inhibitors from expired drugs. International journal of pharmaceutics, 2012, Jul-15, Volume: 431, Issue:1-2 Topics: Acetaminophen; Acetic Acid; Carbamazepine; Corrosion; Recycling; Sodium Acetate; Steel; Sulfuric Acids; Tablets	2012
Occurrence and fate of PPCPs and correlations with water quality parameters in urban riverine waters of the Pearl River Delta, South China. Environmental science and pollution research international, 2013, Volume: 20, Issue:8 Topics: Acetaminophen; Caffeine; Carbamazepine; Carbon; China; Ciprofloxacin; DEET; Environmental Monitoring; Erythromycin; Nitrates; Nitrites; Nitrogen; Pharmaceutical Preparations; Quaternary Ammonium Compounds; Rivers; Sulfamethoxazole; Trimethoprim; Water Pollutants, Chemical; Water Quality	2013
Photo-regenerable multi-walled carbon nanotube membranes for the removal of pharmaceutical micropollutants from water. Environmental science. Processes & impacts, 2013, Volume: 15, Issue:8 Topics: Acetaminophen; Adsorption; Carbamazepine; Hydrogen-Ion Concentration; Ibuprofen; Membranes, Artificial; Microscopy, Electron, Scanning; Nanotubes, Carbon; Photochemical Processes; Titanium; Ultraviolet Rays; Water Pollutants, Chemical; Water Purification	2013
Effect of pharmaceuticals exposure on acetylcholinesterase (AchE) activity and on the expression of AchE gene in the monogonont rotifer, Brachionus koreanus. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2013, Volume: 158, Issue:4 Topics: Acetaminophen; Acetylcholinesterase; Amino Acid Sequence; Analgesics, Non-Narcotic; Animals; Anti-Bacterial Agents; Atenolol; Base Sequence; Biocatalysis; Carbamazepine; Chlorpyrifos; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Helminth Proteins; Molecular Sequence Data; Oxytetracycline; Reverse Transcriptase Polymerase Chain Reaction; Rotifera; Sulfamethoxazole; Time Factors; Trimethoprim; Water Pollutants, Chemical; Xenobiotics	2013
Chlorination of N-methylacetamide and amide-containing pharmaceuticals. Quantum-chemical study of the reaction mechanism. The journal of physical chemistry. A, 2014, Mar-27, Volume: 118, Issue:12 Topics: Acetamides; Acetaminophen; Amides; Carbamazepine; Chemistry, Pharmaceutical; Chlorine; Computer Simulation; Halogenation; Models, Chemical; Molecular Structure; Phenytoin; Quantum Theory; Solvents; Water	2014
The impact of different proportions of a treated effluent on the biotransformation of selected micro-contaminants in river water microcosms. International journal of environmental research and public health, 2014, Oct-10, Volume: 11, Issue:10 Topics: Acetaminophen; Biotransformation; Caffeine; Carbamazepine; Metoprolol; Pharmaceutical Preparations; Rivers; Sewage; Tetrazoles; Valine; Valsartan; Waste Disposal, Fluid; Water Pollutants, Chemical	2014
Evidence of reduced oral bioavailability of paracetamol in rats following multiple ingestion of grapefruit juice. European journal of drug metabolism and pharmacokinetics, 2016, Volume: 41, Issue:2 Topics: Acetaminophen; Animals; Area Under Curve; Beverages; Biological Availability; Carbamazepine; Citrus paradisi; Diclofenac; Eating; Food-Drug Interactions; Male; Rats; Rats, Sprague-Dawley	2016
High-content screening imaging and real-time cellular impedance monitoring for the assessment of chemical's bio-activation with regards hepatotoxicity. Toxicology in vitro : an international journal published in association with BIBRA, 2015, Volume: 29, Issue:7 Topics: Acetaminophen; Amodiaquine; Animals; Carbamazepine; Cell Line, Tumor; Cell Survival; Cells, Cultured; Chemical and Drug Induced Liver Injury; Diethylstilbestrol; Erythromycin; Furosemide; Hepatocytes; High-Throughput Screening Assays; Male; Neutral Red; Rats; Toxicity Tests; Tretinoin	2015
The rest of the story of the patient described in the letter to the editors: 'Hypersensitivity to amoxicillin after… (DRESS) to carbamazepine…: a possible co-sensitization'. British journal of clinical pharmacology, 2016, Volume: 81, Issue:4 Topics: Acetaminophen; Amoxicillin; Carbamazepine; Drug Hypersensitivity Syndrome; Humans; Patch Tests	2016
Adsorption of pharmaceuticals onto activated carbon fiber cloths - Modeling and extrapolation of adsorption isotherms at very low concentrations. Journal of environmental management, 2016, Jan-15, Volume: 166 Topics: Acetaminophen; Adsorption; Caffeine; Carbamazepine; Carbon; Carbon Fiber; Charcoal; Diclofenac; Models, Theoretical; Reproducibility of Results; Water Purification	2016
Oral exposure to immunostimulating drugs results in early changes in innate immune parameters in the spleen. Journal of immunotoxicology, 2016, Volume: 13, Issue:4 Topics: Acetaminophen; Adaptive Immunity; Administration, Oral; Animals; Carbamazepine; Cells, Cultured; Diclofenac; Drug Hypersensitivity; Female; Humans; Immunity, Innate; Immunologic Factors; Immunologic Memory; Killer Cells, Natural; Liver; Mice; Mice, Inbred C3H; Ofloxacin; Spleen; T-Lymphocytes	2016
The role of sorption and biodegradation in the removal of acetaminophen, carbamazepine, caffeine, naproxen and sulfamethoxazole during soil contact: A kinetics study. The Science of the total environment, 2016, 07-15, Volume: 559 Topics: Acetaminophen; Adsorption; Biodegradation, Environmental; Caffeine; Carbamazepine; Kinetics; Models, Chemical; Naproxen; Soil; Soil Pollutants; Spain; Sulfamethoxazole; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical	2016
Evaluation of acute effects of four pharmaceuticals and their mixtures on the copepod Tisbe battagliai. Chemosphere, 2016, Volume: 155 Topics: Acetaminophen; Animals; Carbamazepine; Copepoda; Diclofenac; Ibuprofen; Pharmaceutical Preparations; Toxicity Tests, Acute; Water Pollutants, Chemical	2016
Improving drug safety with a systems pharmacology approach. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2016, Oct-30, Volume: 94 Topics: Acetaminophen; Adverse Drug Reaction Reporting Systems; Analgesics, Non-Narcotic; Anticonvulsants; Carbamazepine; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Molecular Docking Simulation; Pharmacology, Clinical; Stevens-Johnson Syndrome; Systems Biology	2016
Influence of volumetric reduction factor during ozonation of nanofiltration concentrates for wastewater reuse. Chemosphere, 2016, Volume: 165 Topics: Acetaminophen; Atenolol; Carbamazepine; Diatrizoate; Filtration; Nanotechnology; Oxidants; Oxidation-Reduction; Ozone; Recycling; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Water Purification	2016
A multi-omic approach to elucidate low-dose effects of xenobiotics in zebrafish (Danio rerio) larvae. Aquatic toxicology (Amsterdam, Netherlands), 2017, Volume: 182 Topics: Acetaminophen; Animals; Carbamazepine; Diphenhydramine; Dose-Response Relationship, Drug; Fluoxetine; Larva; Metabolome; Models, Animal; Toxicity Tests; Transcriptome; Water Pollutants, Chemical; Xenobiotics; Zebrafish	2017
Mass spectrometry based in vitro assay investigations on the transformation of pharmaceutical compounds by oxidative enzymes. Chemosphere, 2017, Volume: 174 Topics: Acetaminophen; Carbamazepine; Diclofenac; Horseradish Peroxidase; Ibuprofen; Laccase; Mass Spectrometry; Naproxen; Oxidation-Reduction; Sotalol; Sulfamethoxazole; Water Pollutants, Chemical; Water Purification	2017
Investigating natural attenuation of pharmaceuticals through unsaturated column tests. Chemosphere, 2017, Volume: 177 Topics: Acetaminophen; Caffeine; Carbamazepine; Kinetics; Naproxen; Nonlinear Dynamics; Pharmaceutical Preparations; Soil; Soil Pollutants; Sulfamethoxazole; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical	2017
Topical Gabapentin as Add-on Therapy for Trigeminal Neuralgia. A Case Report. Pain medicine (Malden, Mass.), 2017, 09-01, Volume: 18, Issue:9 Topics: Acetaminophen; Administration, Topical; Aged, 80 and over; Analgesics; Carbamazepine; Clonazepam; Drug Therapy, Combination; Female; Gabapentin; Humans; Pain Management; Trigeminal Neuralgia	2017
Transcriptome analysis of the brain of the sea bream (Sparus aurata) after exposure to human pharmaceuticals at realistic environmental concentrations. Marine environmental research, 2017, Volume: 129 Topics: Acetaminophen; Animals; Atenolol; Biomarkers; Brain; Carbamazepine; Fish Proteins; Gene Expression Profiling; Pharmaceutical Preparations; Sea Bream; Transcriptome; Water Pollutants, Chemical	2017
Ozonation as a pretreatment process for nanofiltration brines: Monitoring of transformation products and toxicity evaluation. Journal of hazardous materials, 2017, Sep-15, Volume: 338 Topics: Acetaminophen; Atenolol; Carbamazepine; Chromatography, Liquid; Filtration; Membranes, Artificial; Nanotechnology; Osmosis; Ozone; Salts; Tandem Mass Spectrometry; Toxicity Tests, Acute; Wastewater; Water Pollutants, Chemical; Water Purification	2017
Direct detection of the triphenylpyrylium-derived short-lived intermediates in the photocatalyzed degradation of acetaminophen, acetamiprid, caffeine and carbamazepine. Journal of hazardous materials, 2018, 08-15, Volume: 356 Topics: Acetaminophen; Benzene Derivatives; Caffeine; Carbamazepine; Light; Neonicotinoids; Oxidation-Reduction; Photolysis	2018
Environmentally-relevant mixture of pharmaceutical drugs stimulates sex-steroid hormone production and modulates the expression of candidate genes in the ovary of juvenile female rainbow trout. Aquatic toxicology (Amsterdam, Netherlands), 2018, Volume: 205 Topics: Acetaminophen; Animals; Belgium; Carbamazepine; Diclofenac; Endocrine Disruptors; Female; Gene Expression Regulation; Gonadal Steroid Hormones; Irbesartan; Naproxen; Oncorhynchus mykiss; Ovary; Testosterone; Water Pollutants, Chemical	2018
Clinical Pharmacology Considerations in Pain Management in Patients with Advanced Kidney Failure. Clinical journal of the American Society of Nephrology : CJASN, 2019, 06-07, Volume: 14, Issue:6 Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Analgesics, Opioid; Carbamazepine; Chronic Pain; Gabapentin; Humans; Ketamine; Kidney Failure, Chronic; Neuralgia; Nociceptive Pain; Pain Management; Renal Dialysis	2019
Surface dissolution UV imaging for characterization of superdisintegrants and their impact on drug dissolution. International journal of pharmaceutics, 2020, Mar-15, Volume: 577 Topics: Acetaminophen; Carbamazepine; Carboxymethylcellulose Sodium; Drug Liberation; Excipients; Hydrogen-Ion Concentration; Particle Size; Solubility; Starch; Tablets; Technology, Pharmaceutical; Ultraviolet Rays; Viscosity	2020
Fate and behaviour of acetaminophen, 17α-ethynylestradiol and carbamazepine in aqueous solution. Water science and technology : a journal of the International Association on Water Pollution Research, 2020, Volume: 81, Issue:2 Topics: Acetaminophen; Animals; Carbamazepine; Chlorine; Ethinyl Estradiol; Water Pollutants, Chemical	2020
Effects of chronic exposure to a pharmaceutical mixture on the three-spined stickleback (gasterosteus aculeatus) population dynamics in lotic mesocosms. Aquatic toxicology (Amsterdam, Netherlands), 2020, Volume: 224 Topics: Acetaminophen; Animals; Belgium; Carbamazepine; Diclofenac; Female; Models, Theoretical; Naproxen; Pharmaceutical Preparations; Population Dynamics; Rivers; Smegmamorpha; Water Pollutants, Chemical	2020
Determination of the cross-contamination and validation of the cleaning process for an automated personalised dosing system. European journal of hospital pharmacy : science and practice, 2022, Volume: 29, Issue:3 Topics: Acetaminophen; Carbamazepine; Drug Contamination; Humans; United States	2022
Integrated multi-biomarker responses of juvenile rainbow trout (Oncorhynchus mykiss) to an environmentally relevant pharmaceutical mixture. Ecotoxicology and environmental safety, 2021, Sep-15, Volume: 221 Topics: Acetaminophen; Animals; Belgium; Biomarkers; Brain; Carbamazepine; Diclofenac; Irbesartan; Liver; Lysosomes; Naproxen; Neurotoxicity Syndromes; Oncorhynchus mykiss; Rivers; Serotonin; Water Pollutants, Chemical	2021
Occurrence of pharmaceuticals and cocaine in the urban drainage channels located on the outskirts of the São Vicente Island (São Paulo, Brazil) and related ecological risk assessment. Environmental science and pollution research international, 2022, Volume: 29, Issue:38 Topics: Acetaminophen; Brazil; Caffeine; Carbamazepine; Cocaine; Environmental Monitoring; Humans; Losartan; Pharmaceutical Preparations; Risk Assessment; Water Pollutants, Chemical	2022
First report on the occurrence of pharmaceuticals and cocaine in the coastal waters of Santa Catarina, Brazil, and its related ecological risk assessment. Environmental science and pollution research international, 2022, Volume: 29, Issue:42 Topics: Acetaminophen; Atenolol; Brazil; Caffeine; Carbamazepine; Chromatography, Liquid; Cocaine; Cosmetics; Diclofenac; Ecosystem; Environmental Monitoring; Humans; Losartan; Orphenadrine; Pharmaceutical Preparations; Risk Assessment; Sewage; Solid Waste; Tandem Mass Spectrometry; Water; Water Pollutants, Chemical	2022
Occurrence, ecological risk assessment and prioritization of pharmaceuticals and abuse drugs in estuarine waters along the São Paulo coast, Brazil. Environmental science and pollution research international, 2022, Volume: 29, Issue:59 Topics: Acetaminophen; Atenolol; Brazil; Caffeine; Carbamazepine; Chromatography, Liquid; Cocaine; Diclofenac; Ecosystem; Environmental Monitoring; Furosemide; Illicit Drugs; Losartan; Orphenadrine; Pharmaceutical Preparations; Risk Assessment; Rivers; Tandem Mass Spectrometry; Water Pollutants, Chemical	2022
Comparison of constructed wetland performance coupled with aeration and tubesettler for pharmaceutical compound removal from hospital wastewater. Environmental research, 2023, 01-01, Volume: 216, Issue:Pt 1 Topics: Acetaminophen; Animals; Carbamazepine; Ciprofloxacin; Erythromycin; Hospitals; Ibuprofen; Lorazepam; Pharmaceutical Preparations; Simvastatin; Waste Disposal, Fluid; Wastewater; Wetlands	2023
Photodegradation of a mixture of five pharmaceuticals commonly found in wastewater: Experimental and computational analysis. Environmental research, 2023, 01-01, Volume: 216, Issue:Pt 3 Topics: Acetaminophen; Carbamazepine; Carbon; Diclofenac; Gemfibrozil; Pharmaceutical Preparations; Photolysis; Sulfamethoxazole; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical	2023
On-farm Occurrence of Pharmaceuticals and Their Environmental Hazard: Case Study of a Tropical Dairy farm. Bulletin of environmental contamination and toxicology, 2023, Sep-26, Volume: 111, Issue:4 Topics: Acetaminophen; Animals; Caffeine; Carbamazepine; Environmental Monitoring; Farms; Ibuprofen; Ketoprofen; Pharmaceutical Preparations; Risperidone; Wastewater; Water; Water Pollutants, Chemical	2023