acetaminophen has been researched along with buprenorphine in 44 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (4.55) | 18.7374 |
| 1990's | 6 (13.64) | 18.2507 |
| 2000's | 6 (13.64) | 29.6817 |
| 2010's | 25 (56.82) | 24.3611 |
| 2020's | 5 (11.36) | 2.80 |
| Authors | Studies |
|---|---|
| Crul, BJ; Joosten, HJ; Vollaard, EJ; von Egmond, J; Witjes, WP | 1 |
| Baude, C; Chabrol, B; Long, D; Moskovtchenko, JF | 1 |
| Adelhøj, B; Brynnum, J; Ibsen, M; Petring, OU; Poulsen, HE | 1 |
| Bullingham, RE; McQuay, HJ; Moore, RA; Weir, L | 1 |
| Ejlersen, E; Galatius, H; Hannibal, K; Hansen, A; Obel, E | 1 |
| Delort-Laval, S; Guenard, Y; Krol-Houdek, MC; Maurette, P; Muscagorry, JM; Tauzin-Fin, P | 1 |
| Bannwarth, B; Delort-Laval, S; Krol-Houdek, MC; Maurette, P; Tauzin-Fin, P | 1 |
| Agllata, S; Brini, P; Cardillo, V; Cavagnino, A; Fortina, F; Ragazzoni, E; Sacco, A; Travaglini, S | 1 |
| Martin, WJ; St A Stewart, L | 1 |
| Bertin, P | 1 |
| Carr, WD; Landau, CJ; Munera, C; Razzetti, AJ; Ripa, SR; Sessler, NE | 1 |
| Guo, S; Han, Y; Mai, H; Pan, H; Wang, L; Zhang, G; Zhang, X | 1 |
| Berggren, AC; Karlsson, M | 1 |
| Borchgrevink, PC; Fredheim, OM; Høivik, T; Nordstrand, B; Nøstdahl, T; Rygnestad, T | 1 |
| Conaghan, PG; O'Brien, CM; Schofield, JP; Wilson, M | 1 |
| Endenburg, S; Konings, S; Verkleij, SP | 1 |
| King, OD; Matsumiya, LC; Mogil, JS; Sorge, RE; Sotocinal, SG; Tabaka, JM; Wieskopf, JS; Zaloum, A | 1 |
| Landau, CJ; McCarberg, BH; Munera, C; Ripa, SR; Wen, W | 1 |
| Hale, LP; Kim, CJ; Kolstad, AM; Rodriguiz, RM | 1 |
| Aarsland, D; Ballard, C; Cohen-Mansfield, J; Husebo, BS; Seifert, R | 1 |
| Chang-Chien, GC; Chu, SK; Joseph, P; McCormick, Z | 1 |
| Bounes, V; Jouanjus, E; Lapeyre-Mestre, M; Roussin, A | 1 |
| Christensen, C; Gupta, D; Soskin, V | 1 |
| Aarsland, D; Ballard, C; Corbett, A; Husebo, BS; Sandvik, RK; Seifert, R; Selbaek, G | 1 |
| Breivik, H | 1 |
| Hard, B | 1 |
| Afsharimani, B; Good, P; Hardy, J; Kindl, K | 1 |
| Simpson, RW; Wlodarczyk, JH | 1 |
| Conaghan, PG; Dickerson, S; Junor, R; McSkimming, P; Serpell, M | 1 |
| Bell, RF; Derry, S; Moore, RA; Wee, B; Wiffen, PJ | 1 |
| Athavale, S; Kendall, LV; Lofgren, JL; Nemzek, JA; Oliver, VL; Simon, KE | 1 |
| Bartoli, C; Berland-Benhaim, C; Kintz, P; Leonetti, G; Pelissier-Alicot, AL; Tuchtan-Torrents, L | 1 |
| Bjorvatn, B; Blytt, KM; Flo, E; Husebo, B | 1 |
| Fredheim, OMS | 1 |
| Aarsland, D; Ballard, C; Erdal, A; Flo, E; Husebo, BS; Slettebo, DD | 1 |
| Eng, G; Wakeman, SE; Walley, AY | 1 |
| Bailey, CP; Cordery, SF; Delgado-Charro, MB; Guy, RH; Husbands, SM | 1 |
| Li, FD; Li, WM; Sun, LC; Xu, H | 1 |
| Abelleira, A; Acampora, G; Becker, WC; Falker, CG; Hickey, T; Nazario, M; Weimer, MB | 1 |
| Patel, KV; Sahni, S; Taylor, LF | 1 |
| Bowden, RS; Hyndman, TH; Musk, GC; Riddell, DL | 1 |
| Bagg, MK; Cashin, AG; Furlan, AD; Lee, H; Maher, CG; McAuley, JH; O'Connell, NE; O'Hagan, E; Rizzo, RR; van Tulder, MW; Wand, BM | 1 |
8 review(s) available for acetaminophen and buprenorphine
| Article | Year |
|---|---|
[What are the cardiovascular complications of the analgesics and glucocorticoids?].
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Buprenorphine; Cardiovascular Diseases; Clinical Trials as Topic; Codeine; Dextropropoxyphene; Glucocorticoids; Humans; Morphine; Nalbuphine; Nefopam; Risk Assessment; Risk Factors; Time Factors; Tramadol | 2006 |
[Treatment of acute pain during drug-assisted rehabilitation].
Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Buprenorphine; Glucocorticoids; Humans; Ketamine; Methadone; Opioid-Related Disorders; Pain; Pain, Postoperative; Surgical Procedures, Operative | 2010 |
Management of opioid painkiller dependence in primary care: ongoing recovery with buprenorphine/naloxone.
Topics: Acetaminophen; Analgesics, Opioid; Buprenorphine; Chronic Pain; Codeine; Counseling; Fatigue Syndrome, Chronic; Female; Follow-Up Studies; Humans; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Primary Health Care; Risk Assessment; Severity of Illness Index; Treatment Outcome; Young Adult | 2014 |
Pharmacological options for the management of refractory cancer pain-what is the evidence?
Topics: Acetaminophen; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Buprenorphine; Drug Therapy, Combination; Drug Tolerance; Humans; Methadone; Neoplasms; Pain Management; Pain, Intractable | 2015 |
Opioids for cancer pain - an overview of Cochrane reviews.
Topics: Acetaminophen; Administration, Cutaneous; Administration, Oral; Analgesics, Opioid; Buprenorphine; Cancer Pain; Codeine; Fentanyl; Humans; Hydromorphone; Methadone; Oxycodone; Phenols; Review Literature as Topic; Tapentadol; Tramadol | 2017 |
[Pain management for cancer patients in drug-assisted rehabilitation].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Buprenorphine; Cancer Pain; Humans; Methadone; Opiate Substitution Treatment; Opioid-Related Disorders; Pain Management; Pain Measurement; Pain, Postoperative; Palliative Care; Terminal Care | 2018 |
Perioperative Buprenorphine Management: A Multidisciplinary Approach.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Hip; Buprenorphine; Combined Modality Therapy; Drug Compounding; Female; Humans; Interdisciplinary Communication; Male; Opiate Substitution Treatment; Opioid-Related Disorders; Pain; Pain Management; Pain, Postoperative; Perioperative Care; Receptors, Opioid, mu | 2022 |
Pharmacological treatments for low back pain in adults: an overview of Cochrane Reviews.
Topics: Acetaminophen; Acute Pain; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Buprenorphine; Humans; Low Back Pain; Systematic Reviews as Topic; Tramadol | 2023 |
15 trial(s) available for acetaminophen and buprenorphine
| Article | Year |
|---|---|
Application of sublingual buprenorphine in combination with naproxen or paracetamol for post-operative pain relief in cholecystectomy patients in a double-blind study.
Topics: Acetaminophen; Administration, Sublingual; Adult; Aged; Analgesia, Patient-Controlled; Buprenorphine; Cholecystectomy; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Pain, Postoperative | 1992 |
An oral buprenorphine and paracetamol combination compared with paracetamol alone: a single dose double-blind postoperative study.
Topics: Acetaminophen; Adult; Buprenorphine; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Humans; Male; Morphinans; Pain, Postoperative | 1981 |
Preoperative wound infiltration with bupivacaine reduces early and late opioid requirement after hysterectomy.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Bupivacaine; Buprenorphine; Dermatologic Surgical Procedures; Double-Blind Method; Elective Surgical Procedures; Female; Humans; Hysterectomy; Injections, Subcutaneous; Middle Aged; Pain Measurement; Pain, Postoperative; Placebos; Premedication | 1996 |
[Comparative study of buprenorphine and its combination to ketoprofen or propacetamol for postoperative analgesia in urologic surgery].
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics; Buprenorphine; Drug Therapy, Combination; Female; Humans; Ketoprofen; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Urologic Diseases | 1996 |
Effect of balanced analgesia with buprenorphine on pain response and general anaesthesia requirement during lithotripsy procedures.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Buprenorphine; Double-Blind Method; Female; Humans; Ketoprofen; Kidney Calculi; Lithotripsy; Male; Middle Aged; Pain; Pain Measurement; Premedication | 1998 |
Buprenorphine transdermal delivery system in adults with persistent noncancer-related pain syndromes who require opioid therapy: a multicenter, 5-week run-in and randomized, double-blind maintenance-of-analgesia study.
Topics: Acetaminophen; Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Buprenorphine; Chronic Disease; Double-Blind Method; Drug Delivery Systems; Female; Humans; Male; Middle Aged; Pain; Treatment Failure | 2007 |
Efficacy and safety of low-dose transdermal buprenorphine patches (5, 10, and 20 microg/h) versus prolonged-release tramadol tablets (75, 100, 150, and 200 mg) in patients with chronic osteoarthritis pain: a 12-week, randomized, open-label, controlled, pa
Topics: Acetaminophen; Administration, Cutaneous; Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Buprenorphine; Chronic Disease; Delayed-Action Preparations; Drug Administration Schedule; Humans; Middle Aged; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain; Pain Measurement; Patient Satisfaction; Radiography; Sleep; Sweden; Tablets; Time Factors; Tramadol; Treatment Outcome | 2009 |
Transdermal buprenorphine plus oral paracetamol vs an oral codeine-paracetamol combination for osteoarthritis of hip and/or knee: a randomised trial.
Topics: Acetaminophen; Administration, Cutaneous; Administration, Oral; Aged; Aged, 80 and over; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Buprenorphine; Codeine; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain Measurement; Treatment Outcome | 2011 |
A randomized, 14-day, double-blind study evaluating conversion from hydrocodone/acetaminophen (Vicodin) to buprenorphine transdermal system 10 μg/h or 20 μg/h in patients with osteoarthritis pain.
Topics: Acetaminophen; Administration, Cutaneous; Administration, Oral; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Buprenorphine; Double-Blind Method; Drug Combinations; Drug Substitution; Female; Humans; Hydrocodone; Kaplan-Meier Estimate; Male; Middle Aged; Osteoarthritis; Pain Measurement; Time Factors; Transdermal Patch; Treatment Outcome; United States | 2012 |
The response of agitated behavior to pain management in persons with dementia.
Topics: Acetaminophen; Aged, 80 and over; Analgesics; Buprenorphine; Delayed-Action Preparations; Dementia; Female; gamma-Aminobutyric Acid; Humans; Male; Morphine; Norway; Nursing Homes; Pain; Pain Management; Pregabalin; Psychomotor Agitation; Transdermal Patch | 2014 |
Impact of a stepwise protocol for treating pain on pain intensity in nursing home patients with dementia: a cluster randomized trial.
Topics: Acetaminophen; Activities of Daily Living; Aged; Aged, 80 and over; Analgesics; Buprenorphine; Clinical Protocols; Dementia; Female; gamma-Aminobutyric Acid; Humans; Male; Morphine; Norway; Nursing Homes; Pain; Pain Management; Pain Measurement; Pregabalin; Transdermal Patch; Treatment Outcome | 2014 |
Transdermal Buprenorphine Relieves Neuropathic Pain: A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Trial in Diabetic Peripheral Neuropathic Pain.
Topics: Acetaminophen; Administration, Cutaneous; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Buprenorphine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Double-Blind Method; Female; Humans; Intention to Treat Analysis; Male; Middle Aged; Nausea; Neuralgia; Treatment Outcome; Vomiting; Withholding Treatment | 2016 |
Effects of pain treatment on sleep in nursing home patients with dementia and depression: A multicenter placebo-controlled randomized clinical trial.
Topics: Acetaminophen; Adult; Aged; Analgesics; Buprenorphine; Dementia; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Middle Aged; Norway; Nursing Homes; Pain; Pain Management; Pain Measurement; Sleep Wake Disorders; Transdermal Patch | 2018 |
Efficacy and Safety of Analgesic Treatment for Depression in People with Advanced Dementia: Randomised, Multicentre, Double-Blind, Placebo-Controlled Trial (DEP.PAIN.DEM).
Topics: Acetaminophen; Administration, Cutaneous; Aged, 80 and over; Analgesics; Buprenorphine; Chronic Pain; Dementia; Depression; Double-Blind Method; Female; Humans; Male; Nursing Homes; Treatment Outcome | 2018 |
Analgesic impact of buprenorphine transdermal patch in total hip arthroplasty: A randomized controlled trial protocol.
Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplasty, Replacement, Hip; Buprenorphine; Case-Control Studies; Double-Blind Method; Female; Humans; Length of Stay; Male; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Postoperative Complications; Prospective Studies; Tramadol; Transdermal Patch | 2020 |
21 other study(ies) available for acetaminophen and buprenorphine
| Article | Year |
|---|---|
[Postoperative analgesia for nephrectomy].
Topics: Acetaminophen; Adult; Analgesia, Epidural; Analgesics; Bupivacaine; Buprenorphine; Drug Administration Schedule; Female; Humans; Injections, Intravenous; Male; Meperidine; Middle Aged; Nephrectomy; Pain, Postoperative; Pleura | 1991 |
Buprenorphine delays drug absorption and gastric emptying in man.
Topics: Acetaminophen; Adult; Buprenorphine; Female; Gastric Emptying; Humans; Intestinal Absorption; Male; Morphinans; Pharmaceutical Preparations | 1985 |
[Chronic pain during dialysis. Pharmacologic therapy and its costs].
Topics: Acetaminophen; Analgesics; Arthralgia; Buprenorphine; Chronic Disease; Codeine; Disability Evaluation; Drug Costs; Drug Therapy, Combination; Humans; Italy; Morphine; Neuromuscular Diseases; Pain; Pain Measurement; Renal Dialysis; Vascular Diseases | 1999 |
Drugs for pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents; Aspirin; Asthma; Buprenorphine; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Tolerance; Fentanyl; Humans; Injections; Isoenzymes; Ketorolac; Membrane Proteins; Narcotic Antagonists; Pain; Prostaglandin-Endoperoxide Synthases; Substance-Related Disorders; Tramadol | 2000 |
Evaluation of postoperative analgesia in a rat model of incisional pain.
Topics: Acetaminophen; Analgesia; Analgesics; Animals; Biomechanical Phenomena; Buprenorphine; Clonixin; Fentanyl; Hindlimb; Kinetics; Male; Models, Animal; Pain Measurement; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Weight Gain | 2003 |
Rapamycin, mycophenolate mofetil, methylprednisolone, and cytotoxic T-lymphocyte-associated antigen 4 immunoglobulin-based conditioning regimen to induce partial tolerance to hind limb allografts without cytoreductive conditioning.
Topics: Abatacept; Acetaminophen; Analgesia; Analgesics; Animals; Buprenorphine; Hindlimb; Immune Tolerance; Immunoconjugates; Immunosuppressive Agents; Male; Methylprednisolone; Mycophenolic Acid; Pain, Postoperative; Rats; Rats, Inbred BN; Rats, Inbred Lew; Sirolimus; Transplantation Conditioning; Transplantation, Homologous | 2008 |
Comments on the article by Conaghan et al.
Topics: Acetaminophen; Analgesics; Buprenorphine; Codeine; Female; Humans; Male; Osteoarthritis, Hip; Osteoarthritis, Knee | 2012 |
Using the Mouse Grimace Scale to reevaluate the efficacy of postoperative analgesics in laboratory mice.
Topics: Acetaminophen; Analgesics; Animals; Animals, Laboratory; Buprenorphine; Carbazoles; Dose-Response Relationship, Drug; Facial Expression; Ketoprofen; Mice; Pain Measurement; Pain, Postoperative; Research Design; Time Factors; Video Recording | 2012 |
Effect of pain management on immunization efficacy in mice.
Topics: Acetaminophen; Analgesia; Analgesics; Animals; Animals, Laboratory; Antibody Formation; Behavior, Animal; Buprenorphine; Freund's Adjuvant; Immunization; Lipids; Meloxicam; Mice; Pain; Pain Management; Thiazines; Thiazoles | 2012 |
Acute pain control challenges with buprenorphine/naloxone therapy in a patient with compartment syndrome secondary to McArdle's disease: a case report and review.
Topics: Acetaminophen; Acute Pain; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Buprenorphine; Compartment Syndromes; Creatine Kinase; Drug Combinations; Glycogen Storage Disease Type V; Humans; Hydromorphone; Injections, Intramuscular; Male; Middle Aged; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Pain Measurement; Rhabdomyolysis | 2013 |
Acute pain management for patients under opioid maintenance treatment: what physicians do in emergency departments?
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Buprenorphine; Cross-Sectional Studies; Drug Utilization; Emergency Service, Hospital; Health Care Surveys; Humans; Methadone; Opiate Substitution Treatment; Pain Management; Pain Threshold; Practice Patterns, Physicians' | 2014 |
Marked variability in peri-partum anesthetic management of patients on buprenorphine maintenance therapy (BMT): can there be an underlying acute opioid induced hyperalgesia precipitated by neuraxial opioids in BMT patients?
Topics: Acetaminophen; Adolescent; Adult; Analgesia, Obstetrical; Analgesics, Opioid; Buprenorphine; Cesarean Section; Delivery, Obstetric; Dose-Response Relationship, Drug; Female; Humans; Hydromorphone; Hyperalgesia; Ibuprofen; Opiate Substitution Treatment; Opioid-Related Disorders; Pregnancy; Pregnancy Complications; Retrospective Studies; Young Adult | 2013 |
A high-quality RCT documents that elderly with dementia, the most neglected pain patients, have effective and safe pain relief from paracetamol alone or with buprenorphine patch.
Topics: Acetaminophen; Analgesics; Buprenorphine; Clinical Protocols; Dementia; Female; gamma-Aminobutyric Acid; Humans; Male; Morphine; Pain; Pain Management | 2014 |
Pregnancy: morphine, or sometimes buprenorphine, when paracetamol is ineffective.
Topics: Acetaminophen; Analgesics, Opioid; Buprenorphine; Female; Fetus; Humans; Morphine; Pregnancy | 2016 |
Satisfaction, Adherence and Health-Related Quality of Life with Transdermal Buprenorphine Compared with Oral Opioid Medications in the Usual Care of Osteoarthritis Pain.
Topics: Acetaminophen; Administration, Cutaneous; Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Buprenorphine; Codeine; Drug Combinations; Female; Humans; Male; Medication Adherence; Middle Aged; Osteoarthritis; Pain Measurement; Patient Satisfaction; Prospective Studies; Quality of Life; Severity of Illness Index; Surveys and Questionnaires; Tramadol; United Kingdom | 2016 |
Evaluation of Pain Assessment Techniques and Analgesia Efficacy in a Female Guinea Pig (
Topics: Acetaminophen; Analgesics, Opioid; Animals; Buprenorphine; Carbazoles; Drug Therapy, Combination; Female; Guinea Pigs; Hysterectomy; Pain Management; Pain Measurement; Pain, Postoperative; Specific Pathogen-Free Organisms | 2017 |
Suicide by Medication Overdose in Prison: A Study of Three Cases.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Buprenorphine; Drug Overdose; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Prisoners; Suicide; Young Adult | 2018 |
Case 6-2019: A 29-Year-Old Woman with Nausea, Vomiting, and Diarrhea.
Topics: Acetaminophen; Adult; Buprenorphine; Cocaine-Related Disorders; Diagnosis, Differential; Diarrhea; Drug Combinations; Female; Humans; Illicit Drugs; Naloxone; Narcotic Antagonists; Nausea; Opioid-Related Disorders; Oxycodone; Substance Abuse Detection; Vomiting | 2019 |
Simultaneous Transdermal Delivery of Buprenorphine Hydrochloride and Naltrexone Hydrochloride by Iontophoresis.
Topics: Acetaminophen; Buprenorphine; Drug Delivery Systems; Hydrogen-Ion Concentration; Iontophoresis; Naltrexone | 2019 |
Successful buprenorphine transition while overlapping with a full opioid agonist to treat chronic pain: a case report.
Topics: Acetaminophen; Analgesics, Opioid; Animals; Breakthrough Pain; Buprenorphine; Cattle; Chronic Pain; Female; Humans; Oxycodone; Quality of Life | 2023 |
Use of a Low-calorie Flavored Gel to Facilitate Oral Self-administration of Analgesics in Mice.
Topics: Acetaminophen; Administration, Oral; Analgesics; Animals; Buprenorphine; Female; Male; Meloxicam; Mice; Tramadol | 2023 |