acetaminophen has been researched along with bilirubin in 141 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 43 (30.50) | 18.7374 |
1990's | 12 (8.51) | 18.2507 |
2000's | 29 (20.57) | 29.6817 |
2010's | 44 (31.21) | 24.3611 |
2020's | 13 (9.22) | 2.80 |
Authors | Studies |
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Strassburg, CP; Tukey, RH | 1 |
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
Glen, RC; Lowe, R; Mitchell, JB | 1 |
Douglas, AP; Hamlyn, AN; James, O | 1 |
Siegers, CP | 1 |
Hart, FE; Willson, RA | 1 |
Brunner, G; Büttelmann, B; Holloway, CJ; Husmann, S; Lösgen, H; Scharff, P; Siehoff, A | 1 |
Arnman, R; Olsson, R | 1 |
Davis, M; Gazzard, BG; Goulding, R; Hughes, RD; Widdop, B; Williams, R | 1 |
Davidson, AR; Rojas-Bueno, A; Thompson, RP; Williams, R | 1 |
Gazzard, BG; Henderson, JM; Williams, R | 1 |
Duncan, JR; Finco, DC; Prasse, KW; Schall, WD | 1 |
Khanna, NN; Levy, G; Soda, DM; Stern, L; Tsuzuki, O | 1 |
Davis, M; Harrison, NG; Ideo, G; Williams, R | 1 |
Davidson, AR; Day, DW; Murray-Lyon, IM; Portmann, B; Talbot, IC; Williams, R | 1 |
Funk, C; Knoblauch, M; Lämmli, J | 1 |
Avramova, K; Goranov, I | 1 |
Dutkiewicz, T; Juzwiak, S; Juzyszyn, Z; Krasowska, B; Olenderek, B; Raińska, T; Roźéwicka, L; Samochowiec, L; Wójcicki, J | 1 |
Sherman, SE; Watkins, JB | 1 |
Hughes, RD; Langley, PG; Rolando, N; Williams, R | 1 |
Ebong, PE; Udosen, EO | 1 |
Beckett, GJ; Donovan, JW; Hussey, AJ; Prescott, LF; Proudfoot, AT | 1 |
Ebong, PE; Ekanemessang, UM; Udosen, EO | 1 |
Bock, KW; Bock-Hennig, BS | 1 |
Goldstein, RS; Hook, JB; Morgan, DG; Tarloff, JB | 1 |
Bircher, J; Blume, R; Bock, KW; Schröter, W; Sieg, A; Ullrich, D | 1 |
de Morais, SM; Wells, PG | 1 |
Artwohl, JE; Carter, E; Cera, LM; Henne-Bruns, D | 1 |
Campbell, RJ; Hall, LJ; Halpin, TJ; Holtzhauer, FJ | 1 |
Brown, SS; Prescott, LF; Roscoe, P; Wright, N | 1 |
Borirakchanyavat, V; Clark, R; Davidson, AR; Goulding, R; Thompson, RP; Widdop, B; Williams, R | 1 |
Forrest, AR; Matthew, H; Newton, RW; Prescott, LF; Swainson, CP; Wright, N | 1 |
Matthew, H; Newton, RW; Prescott, LF | 1 |
Forrest, JA; Prescott, LF; Roscoe, P; Stevenson, IH | 1 |
Clark, R; Flute, PT; Rake, MO; Williams, R | 1 |
Chakrabarti, AK; Lloyd, GH | 1 |
Prescott, LF; Wrights, N | 1 |
Matthew, H | 1 |
Borirakchanyavat, V; Clark, R; Flute, PT; Gazzard, BG; Rake, MO; Shilkin, KB; Williams, R | 1 |
Gault, MH; Hebert, MA; Singh, HP | 1 |
Windorfer, A | 1 |
Adjukiewicz, AB; Chalstrey, LJ; Hillenbrand, P; James, IM; Kennedy, J; Parbhoo, SP | 1 |
De la Tour, J; Debray, C; Roze, C; Souchard, M; Vaille, C | 1 |
Ertel, IJ; Levy, G | 1 |
Carroll, JD; Stephens, JD; Toghill, PJ; Williams, R | 1 |
Linden, CH; Rumack, BH | 1 |
Fysh, WJ; Gamsu, HR; Lederman, S; Tredger, M | 1 |
Foster, MG; Wright, LA | 1 |
Hilligoss, D; Kellmeyer, K; Parker, S; Yates, C | 1 |
Wardle, EN; Williams, R | 1 |
Carracio, TR; Mofenson, HC; Singer, AJ | 1 |
Daikuhara, Y; Hughes, RD; Tsubouchi, H; Williams, R; Zhang, L | 1 |
Doyle, S; Rees, GW; Trull, AK | 1 |
Mishra, SH; Rao, KS | 1 |
Andrade, RJ; Camargo, R; García-Escaño, MD; Lucena, MI | 1 |
Lozano Cortés, M; Meléndez Camargo, ME | 1 |
Ishii, H; Ishimura, Y; Kyokane, T; Mori, M; Sano, T; Suematsu, M; Suzuki, H; Yamaguchi, T | 1 |
Kumar, CK; Maiti, BC; Mandal, SC; Mohana Lakshmi, S; Saraswathi, B | 1 |
Bengochea, L; Ghanem, C; Ghisolfi, C; Lemberg, A; Perazzo, JC; Scorticati, C | 1 |
Batlle, AM; Noriega, GO; Ossola, JO; Tomaro, ML | 1 |
Abe, T; Aoki, M; Horiuchi, R; Ishibashi, M; Matsuo, T; Mitsuhashi, H; Ohno, S; Saito, K; Saito, T; Shinzawa, H; Sugahara, K; Takahashi, T; Terui, Y; Togashi, H; Watanabe, H; Yamada, N | 1 |
Banerjee, S; Bhakta, T; Maity, TK; Mandal, SC; Pal, M; Saha, BP | 1 |
Bazooband, A; Bertholf, RL; Johannsen, LM; Mansouri, V | 1 |
DESFORGES, J; GELLIS, S; SILVERBERG, M | 1 |
Han, J; He, P; Li, XD; Lv, Y; Wu, MC; Xia, SQ | 1 |
Kuhlmann, J; Rauchschwalbe, SK; Wensing, G; Zühlsdorf, MT | 1 |
Devaki, T; Ravikumar, V; Shivashangari, KS | 1 |
Evans, RM; Huang, W; Moore, DD; Qatanani, M; Zhang, J | 1 |
Beuhler, MC; Curry, SC | 1 |
Ciszowski, K; Gomółka, E; Jenner, B | 1 |
Davies, P; Kelly, DA; Mahadevan, SB; McKiernan, PJ | 1 |
Boujaoude, J; Honein, K; Moucari, R; Sayegh, R; Slim, R; Yaghi, C | 1 |
Chantharaksri, U; Fucharoen, P; Fucharoen, S; Howard, TA; Morales, NP; Sanvarinda, Y; Sirankapracha, P; Tankanitlert, J; Temsakulphong, A; Ware, RE | 1 |
Akinwande, AI; Alabi-Sofunde, JA; Efedede, BU; Iwalokun, BA; Magbagbeola, OA; Oduala, T | 1 |
Bogdan, GM; Dart, RC; Green, JL; Heard, K; Knox, PC; Kuffner, EK; Palmer, RB; Slattery, JT | 1 |
Balko, JA; Fuller, D; Hynan, LS; Khan, AI; Koff, JM; Lee, WM; Murray, NG; Orsulak, P; Polson, J; Wians, FH | 1 |
Bahr, MJ; Hadem, J; Klempnauer, J; Manns, MP; Rifai, K; Schneider, AS; Stiefel, P; Tillmann, HL; Wedemeyer, H | 1 |
Etani, Y; Mushiake, S; Nakayama, M; Ozono, K; Tajiri, H | 1 |
Bhadauria, M; Nirala, SK | 1 |
Adukauskiene, D; Dockiene, I; Kevelaitis, E; Kupcinskas, L; Naginiene, R; Pundzius, J | 1 |
Nwanna, EE; Oboh, G | 1 |
Kumar, RS; Rajesh, SV; Rajkapoor, B; Raju, K | 1 |
Ancy, P; Anuja, GI; Latha, PG; Rajasekharan, S; Shine, VJ; Shyamal, S; Sini, S; Sreedevi, CD; Suja, SR | 1 |
Allegaert, K; van den Anker, JN; Vanhaesebrouck, S; Verbesselt, R | 1 |
Bala, U; Garba, SH; Sambo, N | 1 |
Das, AK; Roy, CK | 1 |
Al-Jabi, SW; Awang, R; Sulaiman, SA; Zyoud, SH | 1 |
Avizeh, R; Najafzadeh, H; Razijalali, M; Shirali, S | 1 |
Firdous, AP; Kuttan, R; Preethi, KC; Sindhu, ER | 1 |
Fong, BM; Siu, TS; Tam, S | 1 |
Lee, WM | 1 |
Bertholf, RL | 1 |
James, LP; Khandelwal, N; Larson, AM; Lee, WM; Sanders, C | 1 |
Raja, B; Ramachandran, V | 1 |
Firdous, AP; Kuttan, R; Sindhu, ER | 1 |
Li, RS; Shan, LM; Wang, JB; Xiao, XH; Yang, HB; Zhao, YL; Zhou, GD | 1 |
Kavsak, PA; Zeidler, J | 1 |
Chandrasekharan, DK; Menon, A; Nagalekshmi, R; Nair, CK | 1 |
Nwaehujor, CO; Udeh, NE | 1 |
Chen, Y; Jothy, SL; Latha, LY; Nithianantham, K; Sasidharan, S; Shyamala, M | 1 |
Ashok, P; Madhavan, V; Murali, A | 1 |
Chen, Y; Grace-Lynn, C; Jothy, SL; Kanwar, JR; Latha, LY; Sasidharan, S; Vijayarathna, S | 1 |
Sathya, A; Siddhuraju, P | 1 |
Kiran, PM; Raju, AV; Rao, BG | 1 |
Alipour, M; Buonocore, C; Omri, A; Pucaj, K; Suntres, ZE; Szabo, M | 1 |
Dygai, AM; Udut, VV; Vengerovsky, AI | 1 |
Brito, MV; Teixeira, RK; Yamaki, VN; Yasojima, EY | 1 |
Abdel-Azeem, AS; El-Sayed, EM; Farrag, AR; Hegazy, AM; Ibrahim, KS | 1 |
Abo-Elmatty, DM; Aly, HF; Desoky, MM; Ibrahim, N; Rizk, MZ; Younis, EA | 1 |
Li, W; Pu, XP; Sun, H; Sun, Y; Wang, YH; Yang, YF; Zhao, X; Zheng, XY | 1 |
He, Y; Hu, JF; Hu, X; Li, C; Li, T; Liu, M; Liu, Z; Meng, F; Mrsny, RJ; Zeng, X; Zhou, X | 1 |
Aba, PE; Ozioko, IE; Udem, ND; Udem, SC | 1 |
Chong, YK; Lam, HL; Lau, MH; Leung, DC; Mak, CM | 1 |
Chen, YH; Ji, LL; Jiang, P; Sheng, YC; Wang, ZT | 1 |
Brito, MV; Costa, FD; Costa, LA; Teixeira, RK; Vasconcelos, DM; Yamaki, VN; Yasojima, EY | 1 |
Itoh, S; Kusaka, T; Okada, H; Sugino, M | 1 |
Ahmad, A; Kushwah, DS; Salman, MT; Singh, P; Verma, VK | 1 |
Ajiboye, TO | 1 |
Cardinale, M; Craft, J; Meyers, R | 1 |
Abd El-Ghffar, EA; El-Nashar, HA; Eldahshan, OA; Singab, AN | 1 |
Ho, HY; Huang, GJ; Huang, SS; Jiang, WP; Matsuda, Y; Saito, H; Uramaru, N; Wu, JB | 1 |
Cai, L; Cheng, Y; Feng, L; Gao, Y; He, GL; Jiang, ZS; Pan, MX; Zhou, CJ | 1 |
Ahmad, M; Akhtar, N; Asif, HM; Rehman, J; Sultana, S | 1 |
Antoine, DJ; Brillant, N; Burton, NC; Elmasry, M; Fenwick, S; Goldring, CE; Kipar, A; Kitteringham, NR; Park, BK; Poptani, H; Rodriguez, JM; Sharkey, JW | 1 |
Asai, Y; Katoh, M; Nadai, M; Onouchi, H; Sakakibara, Y | 1 |
Aka, C; Koca-Caliskan, U; Sekeroglu, N; Taslidere, A; Yalcin, FN; Yilmaz, I | 1 |
Chan, BY; Lee, HH; Leung, DC; Ling, WH; Mak, CM; Ng, CW; Tsang, HM | 1 |
Ahmed, AAH; Ahmed, AM; Al-Matrafi, TA; Al-Saggaf, S; Alqahtani, HM; AlRabiah, A; Arafah, MM; Atteya, M; Mohammad, RAT; Shereef, SH | 1 |
Asai, S; Ichimura, S; Kakita, H; Kondo, T; Mori, M; Ohashi, W; Okumura, A; Takeshita, S; Ueda, H; Yamada, Y | 1 |
Ali, ES; Asha, UH; Islam, MA; Islam, MT; Kamal, RM; Kumar, M; Mondal, M; Quispe, C; Razis, AFA; Saha, S; Sharifi-Rad, J; Sunusi, U | 1 |
Bellomo, R; Gow, P; Holmes, N; Kishore, K; Marhoon, N; Michel, C; Serpa Neto, A; Sinclair, M; Testro, A; Warming, S; Warrillow, S | 1 |
Hagimoto, S; Iwatani, S; Tamaki, S; Yoshimoto, S | 1 |
Akpulat, HA; Ataseven, H; Filiz, AK; Gezer, A; Karabulut, S; Özkaraca, M; Sahin, B | 1 |
Menisy, GM; Suddek, GM; Zakaria, S | 1 |
Afroze, M; Al-Khafaji, K; Araújo, IM; Asha, UH; Coutinho, HDM; de Lacerda, BCGV; El-Kersh, DM; Islam, MT; Jamaddar, S; Khalipha, ABR; Khan, M; Mondal, M; Moniruzzaman, M; Mori, E; Ray, P; Roy, UK; Sarkar, C; Shill, MC | 1 |
Bai, ZF; Dai, WZ; He, TT; Li, Q; Xiao, XH; Zhan, XY; Zhao, J | 1 |
Hijikata, M; Imaizumi, T; Katayama, D; Morioka, I; Nagano, N; Okahashi, A; Tsuji, Y | 1 |
Ayenew, KD; Wasihun, Y | 1 |
Chen, R; Dai, S; Huang, H; Huang, L; Jiang, X; Jiang, Z; Kou, L; Lin, G; Lu, R; Sun, M; Sun, T; Tang, Y; Xu, Y; Yao, Q; Yao, X; Zheng, S | 1 |
Avachat, C; Barry, JM; Birnbaum, AK; Brink Henriksen, T; Christensen, U; Dalhoff, K; Haslund-Krog, S; Holst, H; Poulsen, S; Remmel, RP; Sherwin, CMT; van den Anker, JN; Wilkins, D | 1 |
Ahmad, S; Ansari, MA; Aslam, M; Chaudhary, SS; Siddiqui, A; Sumaiya, S | 1 |
2 review(s) available for acetaminophen and bilirubin
Article | Year |
---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
Acetaminophen overdose.
Topics: Acetaminophen; Acetylcysteine; Adult; Alanine Transaminase; Aspartate Aminotransferases; Bilirubin; Biotransformation; Chemical and Drug Induced Liver Injury; Child; Cysteine; Dose-Response Relationship, Drug; Glutathione; History, 20th Century; Humans; Kinetics; Liver Diseases; Prognosis; Prothrombin Time; Time Factors | 1984 |
4 trial(s) available for acetaminophen and bilirubin
Article | Year |
---|---|
Controlled trial of cysteamine in treatment of acute paracetamol (acetaminophen) poisoning.
Topics: Acetaminophen; Acute Disease; Adult; Age Factors; Aged; Aspartate Aminotransferases; Bile Acids and Salts; Bilirubin; Clinical Trials as Topic; Cysteamine; Ferritins; Humans; Injections, Intravenous; Liver; Liver Function Tests; Prothrombin; Time Factors | 1976 |
Early changes in coagulation following a paracetamol overdose and a controlled trial of fresh frozen plasma therapy.
Topics: Acetaminophen; Adult; Aspartate Aminotransferases; Bilirubin; Blood Coagulation; Clinical Trials as Topic; Factor V; Factor VII; Fibrinogen; Humans; Infusions, Parenteral; Liver; Plasma; Prothrombin; Prothrombin Time; Substance-Related Disorders; Temperature; Time Factors | 1975 |
The effect of acetaminophen (four grams a day for three consecutive days) on hepatic tests in alcoholic patients--a multicenter randomized study.
Topics: Acetaminophen; Adolescent; Adult; Alanine Transaminase; Alcoholism; Analgesics, Non-Narcotic; Aspartate Aminotransferases; Bilirubin; Female; Fever; Glutathione; Humans; International Normalized Ratio; Liver Diseases, Alcoholic; Male; Middle Aged; Pain; Risk Assessment; Temperance | 2007 |
Evaluation of prophylactic and therapeutic effects of silymarin and N-acetylcysteine in acetaminophen-induced hepatotoxicity in cats.
Topics: Acetaminophen; Acetylcysteine; Animals; Bilirubin; Cat Diseases; Cats; Chemical and Drug Induced Liver Injury; Female; Free Radical Scavengers; Liver; Male; Methemoglobinemia; Protective Agents; Silymarin | 2010 |
135 other study(ies) available for acetaminophen and bilirubin
Article | Year |
---|---|
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Influence of dithiocarb on the biliary excretion of paracetamol and bilirubin in rats.
Topics: Acetaminophen; Animals; Bile; Bilirubin; Ditiocarb; Glucuronates; Male; Rats; Thiocarbamates | 1978 |
Effect of experimental hepatic injury on in vitro drug-metabolizing enzyme activities in the rat.
Topics: Acetaminophen; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Bilirubin; Cytochrome P-450 Enzyme System; Dimethyl Sulfoxide; Glucuronosyltransferase; In Vitro Techniques; Liver; Liver Cirrhosis, Experimental; Male; Microsomes, Liver; Rats | 1977 |
Large agarose beads for extracorporeal detoxification systems.
Topics: Acetaminophen; Animals; Bilirubin; Carrier Proteins; Ethanolamines; Hemoperfusion; Hepatic Encephalopathy; Humans; Hyperbilirubinemia; Phenols; Polysaccharides; Rabbits; Sepharose; Serum Albumin | 1978 |
Elimination of paracetamol in chronic liver disease.
Topics: Acetaminophen; Adolescent; Adult; Aged; Bilirubin; Humans; Liver Cirrhosis; Liver Neoplasms; Middle Aged | 1978 |
Early prediction of the outcome of a paracetamol overdose based on an analysis of 163 patients.
Topics: Acetaminophen; Bilirubin; Chemical and Drug Induced Liver Injury; Cysteamine; Humans; Liver Diseases; Liver Function Tests; Prognosis | 1977 |
Early unconjugated hyperbilirubinaemia after paracetamol overdosage.
Topics: Acetaminophen; Animals; Bilirubin; Chemical and Drug Induced Liver Injury; Female; Humans; Hyperbilirubinemia; Liver; Male; Rats | 1976 |
Acetaminophen toxicosis in the cat.
Topics: Acetaminophen; Administration, Oral; Anemia; Animals; Bilirubin; Blood Urea Nitrogen; Cat Diseases; Cats; Cyanosis; Dehydration; Edema; Face; Female; Fever; Hemoglobinuria; Jaundice; Male | 1975 |
Pharmacokinetics of acetaminophen in the human neonate: formation of acetaminophen glucuronide and sulfate in relation to plasma bilirubin concentration and D-glucaric acid excretion.
Topics: Acetaminophen; Adipates; Age Factors; Bilirubin; Body Weight; Female; Glucuronates; Half-Life; Humans; Infant, Newborn; Kinetics; Liver; Male; Pregnancy; Sugar Acids; Sulfates | 1975 |
Early inhibition of hepatic bilirubin conjugation after paracetamol (acetaminophen) administration in the rat.
Topics: Acetaminophen; Animals; Bilirubin; Liver; Male; Rats; Time Factors | 1975 |
Histopathological changes in the liver following a paracetamol overdose: correlation with clinical and biochemical parameters.
Topics: Acetaminophen; Adolescent; Adult; Bilirubin; Chemical and Drug Induced Liver Injury; Female; Follow-Up Studies; Humans; Liver; Liver Diseases; Liver Function Tests; Male; Middle Aged; Necrosis; Prothrombin Time | 1975 |
[Drug-induced liver diseases].
Topics: Acetaminophen; Adult; Alcoholism; Azathioprine; Bilirubin; Chemical and Drug Induced Liver Injury; Chlorpromazine; Cholestasis; Dihydroxyphenylalanine; Enzyme Induction; Fatty Liver; Female; Granuloma; Halothane; Hepatomegaly; Humans; Male; Middle Aged; Oxyphenisatin Acetate; Pregnancy; Sulfonamides; Tetracycline | 1975 |
[Study of liver glucuronidase function in indirect hyperbilirubinemia and liver cirrhosis].
Topics: Acetaminophen; Bilirubin; Biological Transport; Free Radicals; Glucuronidase; Humans; Hyperbilirubinemia; Jaundice; Liver; Liver Cirrhosis | 1975 |
Caffeine reduces the hepatotoxicity of paracetamol in mice.
Topics: Acetaminophen; Animals; Aspartate Aminotransferases; Bilirubin; Caffeine; Glutathione; Liver; Male; Mice; Mice, Inbred BALB C | 1992 |
Long-term diabetes alters the hepatobiliary clearance of acetaminophen, bilirubin and digoxin.
Topics: Acetaminophen; Animals; Bile; Bilirubin; Diabetes Mellitus, Experimental; Digoxin; Glucuronates; Insulin; Liver; Male; Metabolic Clearance Rate; Rats; Rats, Inbred Strains; Sulfates | 1992 |
Increased elastase-alpha 1-antitrypsin complex in fulminant hepatic failure: relationship to bacterial infection and activation of coagulation.
Topics: Acetaminophen; alpha 1-Antitrypsin; Aspartate Aminotransferases; Bacterial Infections; Bilirubin; Blood Coagulation; Creatinine; Drug Overdose; Enzyme-Linked Immunosorbent Assay; Female; Hepatitis, Viral, Human; Humans; Liver Diseases; Male; Neutrophils; Pancreatic Elastase; Prothrombin Time; Renal Dialysis; Treatment Outcome | 1991 |
The effect of prolonged exposure of rats to sub-lethal dose of acetaminophen.
Topics: Acetaminophen; Alkaline Phosphatase; Animals; Bilirubin; Drug Evaluation, Preclinical; Liver Function Tests; Male; Methemoglobinemia; Rats | 1991 |
Intravenous N-acetylcysteine, hepatotoxicity and plasma glutathione S-transferase in patients with paracetamol overdosage.
Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Aged; Alanine Transaminase; Bilirubin; Chemical and Drug Induced Liver Injury; Female; Glutathione Transferase; Humans; Infusions, Intravenous; Male; Middle Aged | 1990 |
Hepatoxicity evaluation in rats given a single overdose of Acetaminophen (Paracetamol).
Topics: Acetaminophen; Alkaline Phosphatase; Animals; Bilirubin; Chemical and Drug Induced Liver Injury; Liver Diseases; Male; Methemoglobinemia; Rats | 1989 |
Differential induction of human liver UDP-glucuronosyltransferase activities by phenobarbital-type inducers.
Topics: Acetaminophen; Adolescent; Adult; Benzopyrenes; Bilirubin; Carcinoma, Hepatocellular; Enzyme Induction; Female; Glucuronosyltransferase; Humans; Hydroquinones; Hymecromone; Isoenzymes; Liver Neoplasms; Male; Methylcholanthrene; Microsomes, Liver; Middle Aged; Naphthols; Pentobarbital; Phenytoin; Tumor Cells, Cultured | 1987 |
Acetaminophen and p-aminophenol nephrotoxicity in aging male Sprague-Dawley and Fischer 344 rats.
Topics: Acetaminophen; Aging; Aminophenols; Animals; Bilirubin; Chemical and Drug Induced Liver Injury; Kidney; Kidney Tubular Necrosis, Acute; Kidney Tubules, Proximal; Male; Organ Size; Rats; Rats, Inbred F344; Rats, Inbred Strains | 1989 |
Normal pathways for glucuronidation, sulphation and oxidation of paracetamol in Gilbert's syndrome.
Topics: Acetaminophen; Adolescent; Adult; Bilirubin; Female; Gilbert Disease; Glucuronates; Humans; Hyperbilirubinemia, Hereditary; Male; Oxidation-Reduction; Sulfates | 1987 |
Deficiency in bilirubin UDP-glucuronyl transferase as a genetic determinant of acetaminophen toxicity.
Topics: Acetaminophen; Age Factors; Alanine Transaminase; Animals; Bilirubin; Biotransformation; Blood Urea Nitrogen; Glucuronosyltransferase; Liver; Male; Rats; Rats, Gunn; Rats, Inbred Strains; Species Specificity; Sulfates | 1988 |
Acetaminophen toxicosis: a potential model for acute liver failure in swine.
Topics: Acetaminophen; Acute Disease; Animals; Bilirubin; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Female; Liver; Male; Swine | 1988 |
Reye's syndrome. An epidemiologic analysis of mild disease.
Topics: Acetaminophen; Ammonia; Aspirin; Bilirubin; Female; Humans; Male; Reye Syndrome | 1986 |
Plasma-paracetamol half-life and hepatic necrosis in patients with paracetamol overdosage.
Topics: Acetaminophen; Adolescent; Adult; Aged; Bilirubin; Humans | 1971 |
Hepatic damage and death from overdose of paracetamol.
Topics: Acetaminophen; Adolescent; Adult; Aspartate Aminotransferases; Bilirubin; Biopsy; Blood Coagulation Tests; Chemical and Drug Induced Liver Injury; Female; Hepatic Encephalopathy; Humans; Liver; Liver Diseases; Liver Function Tests; Male; Middle Aged; Prothrombin Time; Time Factors | 1973 |
Successful treatment of severe paracetamol overdosage with cysteamine.
Topics: Acetaminophen; Adolescent; Adult; Bilirubin; Blood Cell Count; Blood Urea Nitrogen; Chemical and Drug Induced Liver Injury; Chromatography, Gas; Cysteamine; Dose-Response Relationship, Drug; Female; Humans; Injections, Intravenous; Liver Diseases; Middle Aged; Poisoning; Prothrombin Time; Spectrophotometry; Suicide | 1974 |
Letter: Treatment of paracetamol overdosage.
Topics: Acetaminophen; Aspartate Aminotransferases; Bilirubin; Chemical and Drug Induced Liver Injury; Humans; L-Lactate Dehydrogenase | 1974 |
Abnormal drug metabolism after barbiturate and paracetamol overdose.
Topics: Acetaminophen; Adult; Aged; Alanine Transaminase; Amobarbital; Antipyrine; Barbiturates; Bilirubin; Chemical and Drug Induced Liver Injury; Female; Half-Life; Humans; Liver; Male; Middle Aged; Necrosis | 1974 |
Coagulation abnormalities in acute liver failure; pathogenetic and therapeutic implications.
Topics: Acetaminophen; Acute Disease; Bilirubin; Biopsy; Blood Coagulation Disorders; Blood Coagulation Tests; Blood Transfusion; Chemical and Drug Induced Liver Injury; Disseminated Intravascular Coagulation; Fibrinogen; Hemorrhage; Heparin; Humans; Iodine Radioisotopes; Liver Diseases; Prothrombin Time | 1973 |
Gross paracetamol overdosage with recovery.
Topics: Acetaminophen; Adult; Bilirubin; Chemical and Drug Induced Liver Injury; Humans; Male; Necrosis; Prednisolone; Transaminases | 1973 |
Potentiation by previous drug therapy of hepatotoxicity following paracetamol overdosage.
Topics: Acetaminophen; Adolescent; Adult; Amobarbital; Aspartate Aminotransferases; Bilirubin; Chemical and Drug Induced Liver Injury; Chromatography, Gas; Drug Synergism; Ethanol; Female; Half-Life; Humans; Hydroxybutyrate Dehydrogenase; Imipramine; L-Lactate Dehydrogenase; Liver Diseases; Male; Middle Aged; Necrosis; Phenobarbital | 1973 |
Acute acetaminophen poisoning.
Topics: Acetaminophen; Bilirubin; Blood Coagulation Disorders; Cardiomyopathies; Diuresis; Humans; Hypoglycemia; Kidney Diseases; Liver Diseases; Necrosis; Poisoning; Renal Dialysis | 1973 |
Disorderd hemostasis in liver damage from paracetamol overdose.
Topics: Acetaminophen; Adult; Bilirubin; Blood Cell Count; Blood Coagulation Tests; Blood Platelets; Chemical and Drug Induced Liver Injury; Female; Fibrin; Fibrinogen; Fibrinolysis; Hemostasis; Hepatic Encephalopathy; Humans; Iodine Radioisotopes; Liver Diseases; Liver Function Tests; Male; Middle Aged; Plasminogen; Prothrombin Time | 1973 |
Effect of some drugs on clinical laboratory values as determined by the Technicon SMA 12-60.
Topics: Acetaminophen; Alkaline Phosphatase; Aminosalicylic Acids; Ascorbic Acid; Aspartate Aminotransferases; Autoanalysis; Bilirubin; Blood Chemical Analysis; Blood Glucose; Chemical Phenomena; Chemistry; Cholesterol; Clinical Laboratory Techniques; Dihydroxyphenylalanine; Evaluation Studies as Topic; Humans; Isoniazid; L-Lactate Dehydrogenase; Mercaptopurine; Methyldopa; Pharmaceutical Preparations; Spectrophotometry; Sulfathiazoles; Uric Acid | 1972 |
[Increased rate of glucuronidation in the human and animal newborn by therapeutic doses of phenobarbital].
Topics: Acetaminophen; Administration, Oral; Animals; Animals, Newborn; Bilirubin; Biotransformation; Chromatography, Gas; Enzyme Induction; Evaluation Studies as Topic; Female; Glucuronates; Hexosyltransferases; Humans; Infant, Newborn; Metabolic Clearance Rate; Phenobarbital; Pregnancy; Rabbits; Time Factors | 1972 |
Extracorporeal perfusion of pig liver in the treatment of acute liver failure.
Topics: Acetaminophen; Adult; Animals; Bilirubin; Brain; Chemical and Drug Induced Liver Injury; Electroencephalography; Fatty Liver; Female; Glucose; Hepatic Encephalopathy; Hepatitis A; Hepatitis B; Humans; Liver; Male; Middle Aged; Necrosis; Oxygen Consumption; Perfusion; Radionuclide Imaging; Serum Albumin; Swine; Urea | 1971 |
[Action of an antihypertensive agent on the biliary and external pancreatic secretions of the rat].
Topics: Acetaminophen; Animals; Antihypertensive Agents; Bile; Bilirubin; Blood Glucose; Catecholamines; Diazoxide; Epinephrine; Injections, Intravenous; Insulin; Pancreatic Juice; Rats; Respiration | 1969 |
Effect of bilirubin on drug conjugations in children.
Topics: Acetaminophen; Adult; Bilirubin; Biological Transport, Active; Biotransformation; Child; Female; Glucuronates; Humans; Hyperbilirubinemia, Hereditary; Liver; Oxidative Phosphorylation; Phenobarbital; Salicylamides; Salicylates; Transferases | 1971 |
Acute hepatic necrosis following an overdose of paracetamol.
Topics: Acetaminophen; Acute Disease; Acute Kidney Injury; Adult; Bilirubin; Blood Glucose; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Necrosis; Plasma; Substance-Related Disorders; Suicide; Urea | 1969 |
Neonatal paracetamol poisoning: treatment by exchange transfusion.
Topics: Acetaminophen; Adult; Aspartate Aminotransferases; Bilirubin; Exchange Transfusion, Whole Blood; Female; Humans; Infant, Newborn; Pregnancy; Prothrombin Time | 1983 |
Effect of some commonly prescribed drugs on certain chemistry tests.
Topics: Acetaminophen; Ascorbic Acid; Aspartate Aminotransferases; Aspirin; Bilirubin; Blood Chemical Analysis; Blood Glucose; Calcium; Carbon Dioxide; Cholesterol; Humans; Methyldopa; Nitrofurantoin; Pharmacology; Tetracycline; Uric Acid | 1980 |
Bilirubin interference with kit determination of acetaminophen.
Topics: Acetaminophen; Bilirubin; Humans; Reagent Kits, Diagnostic | 1982 |
Raised serum biliverdin in hepatic necrosis.
Topics: Acetaminophen; Animals; Bile Acids and Salts; Bilirubin; Biliverdine; Chemical and Drug Induced Liver Injury; Cholestasis; Galactosamine; Humans; Liver; Liver Diseases; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Rats | 1981 |
The temporal profile of increased transaminase levels in patients with acetaminophen-induced liver dysfunction.
Topics: Acetaminophen; Aspartate Aminotransferases; Bilirubin; Chemical and Drug Induced Liver Injury; Humans; Liver Diseases; Poisoning; Prospective Studies; Prothrombin Time; Time Factors | 1995 |
Plasma hepatocyte growth factor and biliprotein levels and outcome in fulminant hepatic failure.
Topics: Acetaminophen; Adult; Bilirubin; Enzyme-Linked Immunosorbent Assay; Female; Hepatic Encephalopathy; Hepatocyte Growth Factor; Humans; Liver Regeneration; Liver Transplantation; Male | 1994 |
Evaluation of an enzyme-immunometric assay for serum alpha-glutathione S-transferase.
Topics: Acetaminophen; Alkaline Phosphatase; Analgesics, Non-Narcotic; Analysis of Variance; Arthritis, Rheumatoid; Bilirubin; Evaluation Studies as Topic; Glutathione Transferase; Graft Rejection; Humans; Immunoenzyme Techniques; Kidney Diseases; Liver; Liver Function Tests; Liver Transplantation; Longitudinal Studies; Reagent Kits, Diagnostic; Reference Values; Reproducibility of Results; Rhabdomyolysis; Rheumatoid Factor | 1995 |
Antihepatotoxic activity of monomethyl fumarate isolated from Fumaria indica.
Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bilirubin; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Female; Fumarates; Galactosamine; Liver; Male; Maleates; Plant Extracts; Rats; Rats, Wistar; Rifampin; Silymarin; Thioacetamide | 1998 |
Severe idiosyncratic acute hepatic injury caused by paracetamol.
Topics: Acetaminophen; Adult; Alanine Transaminase; Analgesics, Non-Narcotic; Aspartate Aminotransferases; Bilirubin; Bronchitis; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Roxithromycin | 1998 |
Renal and hepatic interactions of acetaminophen and amikacin in the infant rat.
Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Amikacin; Analgesics, Non-Narcotic; Animals; Animals, Newborn; Anti-Bacterial Agents; Bilirubin; Creatinine; Dose-Response Relationship, Drug; Drug Interactions; Female; Glucose; Kidney; Liver; p-Aminohippuric Acid; Potassium; Proteins; Rats; Rats, Wistar; Sodium | 1998 |
Carbon monoxide-mediated alterations in paracellular permeability and vesicular transport in acetaminophen-treated perfused rat liver.
Topics: Acetaminophen; Animals; Bile; Bilirubin; Carbon Monoxide; Cell Membrane Permeability; Cholestasis; Clotrimazole; Cytochrome P-450 Enzyme System; Heme Oxygenase (Decyclizing); Liver; Male; Microsomes, Liver; Perfusion; Protoporphyrins; Rats; Rats, Wistar | 1999 |
Protective effect of leaf extract of Ficus hispida Linn. against paracetamol-induced hepatotoxicity in rats.
Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bilirubin; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Female; Liver; Liver Diseases; Male; Plant Extracts; Plant Leaves; Random Allocation; Rats; Rats, Wistar; Rosales | 2000 |
[Does TNF-alpha contribute to liver disease physiopathology?].
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Aspartate Aminotransferases; Bilirubin; Cholestasis; Kidney Diseases; Liver; Male; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2000 |
Effect of acetaminophen on heme metabolism in rat liver.
Topics: 5-Aminolevulinate Synthetase; Acetaminophen; Animals; Bilirubin; Female; Heme; Injections, Intraperitoneal; Lipid Peroxidation; Liver; Oxidative Stress; Porphobilinogen Synthase; Rats; Rats, Wistar; S-Adenosylmethionine | 2000 |
Acute cholestatic hepatitis caused by a probable allergic reaction to paracetamol in an adolescent.
Topics: Acetaminophen; Acute Disease; Adolescent; Analgesics, Non-Narcotic; Bilirubin; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Drug Hypersensitivity; Female; Hepatitis, Viral, Human; Humans; Liver Function Tests; Lymphocyte Activation | 2001 |
Hepatoprotective activity of Cassia fistula leaf extract.
Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bilirubin; Chemical and Drug Induced Liver Injury; Fabaceae; Female; Hepatocytes; India; Liver; Liver Diseases; Male; Medicine, East Asian Traditional; Plant Extracts; Plant Leaves; Plants, Medicinal; Protective Agents; Rats; Rats, Wistar | 2001 |
False-positive acetaminophen results in a hyperbilirubinemic patient.
Topics: Acetaminophen; Adolescent; Bilirubin; False Positive Reactions; Humans; Hyperbilirubinemia; Jaundice; Male | 2003 |
MECHANISMS UNDERLYING VITAMIN K INDUCED HYPERBILIRUBINEMIA IN PREMATURE INFANTS.
Topics: Acetaminophen; Acetanilides; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Bilirubin; Erythrocytes; Glucosephosphate Dehydrogenase; Glucuronates; Glutathione; Hemolysis; Humans; Hyperbilirubinemia; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Pharmacology; Toxicology; Vitamin K | 1963 |
Conjugation metabolism of acetaminophen and bilirubin in extrahepatic tissues of rats.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Bilirubin; Biotransformation; Chromatography, High Pressure Liquid; Glucuronides; Histamine H2 Antagonists; Hypnotics and Sedatives; Liver Function Tests; Phenobarbital; Ranitidine; Rats; Rats, Sprague-Dawley; Sulfates | 2004 |
Glucuronidation of acetaminophen is independent of UGT1A1 promotor genotype.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Bilirubin; Genotype; Gilbert Disease; Glucuronosyltransferase; Humans; Male; Polymorphism, Genetic; Promoter Regions, Genetic | 2004 |
Evaluation of the protective efficacy of Asteracantha longifolia on acetaminophen-induced liver damage in rats.
Topics: Acanthaceae; Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bilirubin; Chemical and Drug Induced Liver Injury; Cholesterol; Fatty Acids, Nonesterified; gamma-Glutamyltransferase; L-Lactate Dehydrogenase; Liver; Liver Diseases; Methanol; Phytotherapy; Plant Extracts; Rats; Seeds; Triglycerides | 2004 |
The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity.
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Aryl Hydrocarbon Hydroxylases; Bile Acids and Salts; Bilirubin; Blotting, Northern; Clotrimazole; Constitutive Androstane Receptor; Cytochrome P-450 CYP3A; Detergents; Dieldrin; Growth Inhibitors; Lithocholic Acid; Liver; Membrane Proteins; Mice; Mice, Knockout; Models, Biological; Oxidoreductases, N-Demethylating; Phenotype; Pregnane X Receptor; Protein Binding; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; RNA; Sodium; Transcription Factors | 2004 |
False positive acetaminophen levels associated with hyperbilirubinemia.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Bilirubin; Enzyme Multiplied Immunoassay Technique; False Positive Reactions; Gas Chromatography-Mass Spectrometry; Humans; Hyperbilirubinemia; Reagent Kits, Diagnostic | 2005 |
[The influence of the dose, time since ingestion and concentration of the xenobiotic on the clinical state and severity of liver damage with patients intoxicated with paracetamol].
Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Bilirubin; Biomarkers; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Overdose; Female; Humans; Liver Failure, Acute; Liver Function Tests; Male; Middle Aged; Poland; Retrospective Studies; Severity of Illness Index; Time Factors; Transaminases; Xenobiotics | 2005 |
Paracetamol induced hepatotoxicity.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Bilirubin; Blood Glucose; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Creatinine; Drug Overdose; Female; Humans; Infant; Liver; Liver Diseases; Male; Prognosis; Retrospective Studies; Risk Factors; Transaminases | 2006 |
Influence of acetaminophen at therapeutic doses on surrogate markers of severity of acute viral hepatitis.
Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Bilirubin; Biomarkers; Female; Hepatitis, Viral, Human; Humans; Male; Middle Aged; Prospective Studies; Prothrombin Time; Severity of Illness Index | 2006 |
A pharmacokinetic study of paracetamol in Thai beta-thalassemia/HbE patients.
Topics: Acetaminophen; Adult; Area Under Curve; beta-Thalassemia; Bilirubin; Cysteine; Female; Glucuronosyltransferase; Humans; Male; Middle Aged | 2006 |
Hepatoprotective and antioxidant activities of Vernonia amygdalina on acetaminophen-induced hepatic damage in mice.
Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Aspartate Aminotransferases; Bilirubin; Catalase; Chemical and Drug Induced Liver Injury; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Liver Diseases; Medicine, Traditional; Mice; Nigeria; Oxidative Stress; Phytotherapy; Plant Extracts; Plant Leaves; Thiobarbituric Acid Reactive Substances; Vernonia | 2006 |
False positive acetaminophen concentrations in patients with liver injury.
Topics: Acetaminophen; Aged; Bilirubin; Drug Overdose; False Positive Reactions; Female; Humans; Hyperbilirubinemia; Liver Failure, Acute; Liver Function Tests; Male; Middle Aged | 2008 |
Prognostic implications of lactate, bilirubin, and etiology in German patients with acute liver failure.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Bilirubin; Biomarkers; Budd-Chiari Syndrome; Female; Follow-Up Studies; Germany; Hepatitis B; Humans; Incidence; Lactic Acid; Liver Failure, Acute; Male; Middle Aged; Multivariate Analysis; Prognosis; Retrospective Studies; Risk Factors; ROC Curve; Survival Rate | 2008 |
A favorable response to steroid therapy in a child with drug-associated acute vanishing bile duct syndrome and skin disorder.
Topics: Acetaminophen; Bile Acids and Salts; Bile Duct Diseases; Bilirubin; Cefdinir; Cephalosporins; Child; Erythema Multiforme; Humans; Male; Methylprednisolone; Syndrome | 2008 |
Propolis reverses acetaminophen induced acute hepatorenal alterations: a biochemical and histopathological approach.
Topics: Acetaminophen; Acid Phosphatase; Adenosine Triphosphatases; Alkaline Phosphatase; Animals; Antioxidants; Bilirubin; Blood Glucose; Chemical and Drug Induced Liver Injury; Cholesterol; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Female; Glutathione; Glycogen; Hemoglobins; Kidney; Kidney Diseases; L-Lactate Dehydrogenase; Liver; Liver Diseases; Malondialdehyde; Oxidative Stress; Propolis; Rats; Rats, Sprague-Dawley; Silymarin; Transaminases | 2008 |
Acute liver failure in Lithuania.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Bilirubin; Chemical and Drug Induced Liver Injury; Confidence Intervals; Data Interpretation, Statistical; Fatty Liver; Female; Hepatic Encephalopathy; Hepatitis; Humans; Lithuania; Liver Failure, Acute; Liver Transplantation; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Pregnancy; Pregnancy Complications; Prognosis; Prospective Studies; Prothrombin; Risk Factors | 2008 |
Antioxidant and hepatoprotective properties of polyphenol extracts from Telfairia occidentalis (fluted pumpkin) leaves on acetaminophen induced liver damage.
Topics: Acetaminophen; Animals; Antioxidants; Aspartate Aminotransferases; Bilirubin; Cucurbita; Flavonoids; Free Radical Scavengers; Humans; Liver; Medicine, Traditional; Nigeria; Phenols; Plant Extracts; Plant Leaves; Polyphenols; Rats; Rats, Wistar | 2007 |
Effect of Clausena dentata (Willd.) M. Roem. against paracetamol induced hepatotoxicity in rats.
Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bilirubin; Chemical and Drug Induced Liver Injury; Clausena; Disease Models, Animal; gamma-Glutamyltransferase; Liver; Liver Diseases; Male; Plant Bark; Plant Extracts; Protective Agents; Rats; Rats, Wistar; Silymarin | 2009 |
Hepatoprotective studies on Sida acuta Burm. f.
Topics: Acetaminophen; Alkaline Phosphatase; Animals; Bilirubin; Chemical and Drug Induced Liver Injury; Coumaric Acids; Hexobarbital; Liver; Male; Malvaceae; Mice; Phytotherapy; Plant Extracts; Plant Roots; Protective Agents; Rats; Rats, Wistar; Stupor; Transaminases | 2009 |
In vivo glucuronidation activity of drugs in neonates: extensive interindividual variability despite their young age.
Topics: Acetaminophen; Age Factors; Bilirubin; Glucuronides; Glucuronosyltransferase; Humans; Infant, Newborn; Metabolic Clearance Rate; Morphine; Polymorphism, Genetic; Propofol | 2009 |
The effect of the aqueous extract of Kohautia grandiflora on paracetamol-induced liver damage in albino rats.
Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bilirubin; Biomarkers; Body Weight; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Liver; Plant Extracts; Rats; Rubiaceae; Serum Albumin | 2009 |
Comparative evaluation of different extracts of leaves of Psidium guajava Linn. for hepatoprotective activity.
Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bilirubin; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Liver; Male; Phytotherapy; Plant Extracts; Plant Leaves; Psidium; Rats; Rats, Wistar; Silymarin; Solvents | 2010 |
Association between gastrointestinal manifestations following acetaminophen poisoning and outcome in 291 acetaminophen poisoning patients.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Bilirubin; Chemical and Drug Induced Liver Injury; Cohort Studies; Creatinine; Diarrhea; Female; Humans; Length of Stay; Logistic Models; Malaysia; Male; Nausea; Pharmacoepidemiology; Potassium; Prevalence; Prognosis; Prothrombin Time; Retrospective Studies; Statistics, Nonparametric; Vomiting; Young Adult | 2010 |
Carotenoid lutein protects rats from paracetamol-, carbon tetrachloride- and ethanol-induced hepatic damage.
Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Aspartate Aminotransferases; Bilirubin; Biomarkers; Carbon Tetrachloride; Catalase; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Glutathione Peroxidase; Hydroxyproline; Lipid Peroxidation; Liver; Lutein; Male; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase | 2010 |
Persistently increased acetaminophen concentrations in a patient with acute liver failure.
Topics: Acetaminophen; Adult; Bilirubin; Diagnosis, Differential; False Positive Reactions; Female; Humans; Liver Failure, Acute; Ultrafiltration | 2011 |
Commentary.
Topics: Acetaminophen; Acetylcysteine; Bilirubin; Diagnosis, Differential; False Positive Reactions; Female; Humans; Liver Failure, Acute | 2011 |
Commentary.
Topics: Acetaminophen; Bilirubin; Colorimetry; Diagnosis, Differential; False Positive Reactions; Humans; Immunoassay; Liver Failure, Acute; Ultrafiltration | 2011 |
Unrecognized acetaminophen toxicity as a cause of indeterminate acute liver failure.
Topics: Acetaminophen; Acetylcysteine; Adult; Analgesics, Non-Narcotic; Bilirubin; Chemical and Drug Induced Liver Injury; Drug Overdose; Female; Free Radical Scavengers; Humans; Liver Failure, Acute; Male; Middle Aged; Prognosis; Retrospective Studies; Severity of Illness Index; Survival Rate; Transaminases | 2011 |
Protective effects of syringic acid against acetaminophen-induced hepatic damage in albino rats.
Topics: Acetaminophen; Administration, Oral; Animals; Antioxidants; Bilirubin; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Gallic Acid; Kidney; Lipid Peroxidation; Liver; Male; Protective Agents; Rats; Rats, Wistar | 2010 |
Hepato-protective potential of carotenoid meso-zeaxanthin against paracetamol, CCl4 and ethanol induced toxicity.
Topics: Acetaminophen; Animals; Antioxidants; Bilirubin; Biomarkers; Carbon Tetrachloride; Catalase; Dose-Response Relationship, Drug; Ethanol; Glutathione; Glutathione Peroxidase; Liver; Male; Oxidative Stress; Protective Agents; Rats; Rats, Wistar; Superoxide Dismutase; Xanthophylls; Zeaxanthins | 2011 |
Rhein protects against acetaminophen-induced hepatic and renal toxicity.
Topics: Acetaminophen; Alanine Transaminase; Animals; Anthraquinones; Antioxidants; Bilirubin; Chemical and Drug Induced Liver Injury; Creatinine; Glutathione; Kidney; Kidney Diseases; Liver; Male; Nitric Oxide; Nitrogen; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2011 |
An alternative approach for detecting interferences in enzymatic acetaminophen assays.
Topics: Acetaminophen; Bilirubin; Enzymes; False Positive Reactions; Humans; Indicators and Reagents | 2011 |
Hepatoprotective activity of Andrographis paniculata and Swertia chirayita.
Topics: Acetaminophen; Administration, Oral; Alanine Transaminase; Alkaline Phosphatase; Andrographis; Animals; Aspartate Aminotransferases; Bilirubin; Biomarkers; Catalase; Chemical and Drug Induced Liver Injury; Female; Glutathione; Glutathione Peroxidase; India; Lipid Peroxides; Liver; Mice; Plant Extracts; Plants, Medicinal; Superoxide Dismutase; Swertia | 2011 |
Screening of ethyl acetate extract of Bridelia micrantha for hepatoprotective and anti-oxidant activities on Wistar rats.
Topics: Acetaminophen; Acetates; Alanine Transaminase; Alkaline Phosphatase; Analgesics, Non-Narcotic; Animals; Aspartate Aminotransferases; Bilirubin; Biological Assay; Biphenyl Compounds; Blood Proteins; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Euphorbiaceae; Ferric Compounds; Free Radicals; Humans; Male; Phytotherapy; Picrates; Plant Extracts; Plant Leaves; Rats; Rats, Wistar | 2011 |
Hepatoprotective potential of Clitoria ternatea leaf extract against paracetamol induced damage in mice.
Topics: Acetaminophen; Animals; Antioxidants; Bilirubin; Biomarkers; Biphenyl Compounds; Butylated Hydroxytoluene; Chemical and Drug Induced Liver Injury; Clitoria; Flavonoids; Free Radical Scavengers; Inhibitory Concentration 50; Liver; Male; Mice; Phenols; Phytotherapy; Picrates; Plant Extracts; Plant Leaves; Protective Agents; Reference Standards | 2011 |
Effect of Smilax zeylanica roots and rhizomes in paracetamol induced hepatotoxicity.
Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Analgesics, Non-Narcotic; Animals; Antidotes; Aspartate Aminotransferases; Bilirubin; Chemical and Drug Induced Liver Injury; Female; Liver; Male; Phytotherapy; Plant Extracts; Plant Roots; Rats; Rats, Wistar; Rhizome; Serum Albumin; Smilax | 2012 |
Evaluation of the hepatoprotective Effects of Lantadene A, a pentacyclic triterpenoid of Lantana plants against acetaminophen-induced liver damage.
Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bilirubin; Chemical and Drug Induced Liver Injury; Humans; Lantana; Liver; Mice; Oleanolic Acid; Plant Leaves; Protective Agents; Silymarin | 2012 |
Protective effect of bark and empty pod extracts from Acacia auriculiformis against paracetamol intoxicated liver injury and alloxan induced type II diabetes.
Topics: Acacia; Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Alloxan; Animals; Aspartate Aminotransferases; Bilirubin; Biomarkers; Blood Glucose; Catalase; Chemical and Drug Induced Liver Injury; Cholesterol; Creatinine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glutathione; Glutathione Peroxidase; Hypoglycemic Agents; Liver; Plant Bark; Plant Extracts; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2013 |
Investigation of hepatoprotective activity of Cyathea gigantea (Wall. ex. Hook.) leaves against paracetamol-induced hepatotoxicity in rats.
Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Analgesics, Non-Narcotic; Animals; Antioxidants; Aspartate Aminotransferases; Bilirubin; Chemical and Drug Induced Liver Injury; Liver; Phytotherapy; Plant Extracts; Plant Leaves; Rats; Rats, Wistar | 2012 |
Therapeutic effect of liposomal-N-acetylcysteine against acetaminophen-induced hepatotoxicity.
Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Bilirubin; Body Weight; Chemical and Drug Induced Liver Injury; Chemistry, Pharmaceutical; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Lipid Peroxidation; Liposomes; Liver; Male; Peroxidase; Rats; Rats, Sprague-Dawley | 2013 |
Effects of phospholipid hepatoprotectors on apoptosis during experimental liver pathology induced by isoniazid and paracetamol.
Topics: Acetaminophen; Alkaline Phosphatase; Animals; Apoptosis; Bilirubin; Carotenoids; Chemical and Drug Induced Liver Injury; Drug Combinations; Granulocytes; Interleukin-10; Isoniazid; Liver Function Tests; Lymphocytes; Male; Phosphatidylcholines; Phospholipids; Rats; Succinic Acid; Transaminases; Tumor Necrosis Factor-alpha | 2013 |
Effect of copaiba oil in hepatic damage induced by acetaminophen in rats.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Bilirubin; Chemical and Drug Induced Liver Injury; Fabaceae; Male; Plant Oils; Random Allocation; Rats; Rats, Wistar; Reproducibility of Results; Time Factors; Treatment Outcome | 2013 |
Hepatoprotective, antioxidant, and ameliorative effects of ginger (Zingiber officinale Roscoe) and vitamin E in acetaminophen treated rats.
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Antioxidants; Aspartate Aminotransferases; Bilirubin; Blood Proteins; Chemical and Drug Induced Liver Injury; Lipid Peroxidation; Liver; Male; Malondialdehyde; Necrosis; Oxidative Stress; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Triglycerides; Vitamin E; Zingiber officinale | 2013 |
Hepatoprotective effect of Caesalpinia gilliesii and Cajanus cajan proteins against acetoaminophen overdose-induced hepatic damage.
Topics: Acetaminophen; Adenosine Triphosphatases; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bilirubin; Caesalpinia; Cajanus; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Dose-Response Relationship, Drug; Glutathione; Interleukin-6; L-Lactate Dehydrogenase; Liver; Male; Nitric Oxide; Peroxidase; Plant Extracts; Plant Proteins; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2016 |
Two xanthones from Swertia punicea with hepatoprotective activities in vitro and in vivo.
Topics: Acetaminophen; Animals; Aspartate Aminotransferases; Bilirubin; Carbon Tetrachloride; Cell Survival; Dimethylnitrosamine; Glutathione; Hep G2 Cells; Humans; L-Lactate Dehydrogenase; Liver; Liver Cirrhosis; Male; Malondialdehyde; Protective Agents; Rats, Wistar; Reactive Oxygen Species; Serum Albumin; Superoxide Dismutase; Swertia; Xanthones | 2014 |
Human umbilical cord mesenchymal stromal cells rescue mice from acetaminophen-induced acute liver failure.
Topics: Acetaminophen; Administration, Intravenous; Alanine Transaminase; Animals; Aspartate Aminotransferases; Bilirubin; Cell Differentiation; Cells, Cultured; Disease Models, Animal; Humans; Liver; Liver Failure, Acute; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice, Inbred BALB C; Umbilical Cord | 2014 |
Some biochemical and haematological changes in rats pretreated with aqueous stem bark extract of Lophira lanceolata and intoxicated with paracetamol (acetaminophen).
Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bilirubin; Chemical and Drug Induced Liver Injury; Female; Liver; Male; Ochnaceae; Plant Bark; Plant Extracts; Plant Stems; Rats; Rats, Wistar; Water | 2014 |
Bi-variate approach to negative interference of bilirubin towards an acetaminophen assay.
Topics: Acetaminophen; Bilirubin; Biological Assay; Humans; Regression Analysis; Reproducibility of Results | 2015 |
Protection of Flos Lonicerae against acetaminophen-induced liver injury and its mechanism.
Topics: Acetaminophen; Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Bilirubin; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Gene Expression Regulation; Glutamate-Cysteine Ligase; Lonicera; Male; Mice; Mice, Inbred ICR; Polyphenols | 2014 |
Attenuation of copaiba oil in hepatic damage in rats.
Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bilirubin; Chemical and Drug Induced Liver Injury; Corn Oil; Disease Models, Animal; Fabaceae; gamma-Glutamyltransferase; Male; Plant Oils; Random Allocation; Rats, Wistar; Treatment Outcome | 2014 |
Evaluation of bilirubin displacement effect by acetaminophen in vitro.
Topics: Acetaminophen; Anti-Infective Agents; Antipyretics; Bilirubin; Binding, Competitive; Humans; In Vitro Techniques; Peroxidases; Protein Binding; Serum Albumin; Sulfisoxazole | 2015 |
Protective effects of ethanolic extract of Nigella sativa seed in paracetamol induced acute hepatotoxicity in vivo.
Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Apoptosis; Aspartate Aminotransferases; Bilirubin; Biomarkers; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Ethanol; Glutathione; Liver; Male; Necrosis; Nigella sativa; Phytotherapy; Plant Extracts; Plants, Medicinal; Rats, Wistar; Seeds; Solvents; Time Factors | 2014 |
Lophirones B and C Attenuate Acetaminophen-Induced Liver Damage in Mice: Studies on Hepatic, Oxidative Stress and Inflammatory Biomarkers.
Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Animals; Anti-Inflammatory Agents; Antioxidants; Aspartate Aminotransferases; Benzopyrans; Bilirubin; Catalase; Chemical and Drug Induced Liver Injury; Glucosephosphate Dehydrogenase; Glutathione Peroxidase; Glutathione Reductase; Interleukin-6; Interleukin-8; Liver; Male; Malpighiaceae; Mice; Oxidative Stress; Plant Extracts; Serum Albumin; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2016 |
Falsely elevated acetaminophen levels in a patient with extreme hyperbilirubinemia.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Bilirubin; Colorimetry; Humans; Hyperbilirubinemia; Male | 2016 |
GC-MS analysis and hepatoprotective activity of the n-hexane extract of Acrocarpus fraxinifolius leaves against paracetamol-induced hepatotoxicity in male albino rats.
Topics: Acetaminophen; Animals; Antioxidants; Bilirubin; Biomarkers; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Dose-Response Relationship, Drug; Fabaceae; Gas Chromatography-Mass Spectrometry; Hexanes; Lethal Dose 50; Lipids; Liver; Male; Organ Size; Oxidative Stress; Phytotherapy; Plant Extracts; Plant Leaves; Plants, Medicinal; Rats, Wistar; Solvents; Weight Loss | 2017 |
Protective Effects of Tormentic Acid, a Major Component of Suspension Cultures of Eriobotrya japonica Cells, on Acetaminophen-Induced Hepatotoxicity in Mice.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Bilirubin; Catalase; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cholesterol; Cyclooxygenase 2; Eriobotrya; Glutathione Peroxidase; Injections, Intraperitoneal; Interleukin-1beta; Interleukin-6; Liver; Male; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; Protective Agents; Reactive Oxygen Species; Superoxide Dismutase; Triglycerides; Triterpenes; Tumor Necrosis Factor-alpha | 2017 |
Artificial liver support in pigs with acetaminophen-induced acute liver failure.
Topics: Acetaminophen; Ammonia; Animals; Aspartate Aminotransferases; Bilirubin; Cell Nucleus; Creatinine; Disease Models, Animal; Hepatocytes; Liver; Liver Failure, Acute; Liver, Artificial; Sus scrofa; Swine; Time Factors | 2017 |
Hepatoprotective evaluation of aqueous-ethanolic extract of Capparis decidua (Stems) in paracetamol induced hepatotoxicity in experimental rabbits.
Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bilirubin; Capparis; Dose-Response Relationship, Drug; Female; Liver; Male; Phytochemicals; Plant Extracts; Plant Stems; Rabbits | 2017 |
Dynamic and accurate assessment of acetaminophen-induced hepatotoxicity by integrated photoacoustic imaging and mechanistic biomarkers in vivo.
Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Animals; Bilirubin; Biomarkers; Cell Survival; Chemical and Drug Induced Liver Injury; Glutathione; HMGB1 Protein; Liver; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Photoacoustic Techniques | 2017 |
Characterization of β-Estradiol 3-Glucuronidation in Rat Brain.
Topics: Acetaminophen; Animals; Bilirubin; Brain Chemistry; Cerebellum; Estradiol; Glucuronides; Glucuronosyltransferase; Isoenzymes; Kinetics; Liver; Male; Microsomes; Rats; Rats, Sprague-Dawley; Serotonin | 2017 |
Cuscuta arvensis Beyr "Dodder": In Vivo Hepatoprotective Effects Against Acetaminophen-Induced Hepatotoxicity in Rats.
Topics: Acetaminophen; Alkaline Phosphatase; Animals; Antioxidants; Aspartate Aminotransferases; Bilirubin; Catalase; Chemical and Drug Induced Liver Injury; Cuscuta; Female; Humans; Liver; Malondialdehyde; Plant Extracts; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2018 |
Performance evaluation of five commercial assays for detection of acetaminophen.
Topics: Acetaminophen; Acetylcysteine; Bilirubin; Hemolysis; Humans; Immunoenzyme Techniques; Linear Models; Reproducibility of Results; Sensitivity and Specificity | 2019 |
Thymoquinone and curcumin modify inducible nitric oxide synthase, caspase 3, and thioredoxin immunohistochemical expression in acetaminophen hepatotoxicity.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Benzoquinones; Bilirubin; Caspase 3; Curcumin; Glutathione; Immunohistochemistry; Liver; Liver Diseases; Male; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Superoxide Dismutase; Thioredoxins | 2019 |
Acetaminophen elevates unbound bilirubin levels by the glucose oxidase-peroxidase method.
Topics: Acetaminophen; Bilirubin; Glucose Oxidase; Humans; Infant; Infant, Newborn; Jaundice, Neonatal; Oxidoreductases; Peroxidase; Peroxidases; Retrospective Studies | 2021 |
Effects of nerol on paracetamol-induced liver damage in Wistar albino rats.
Topics: Acetaminophen; Acyclic Monoterpenes; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Aspartate Aminotransferases; Bilirubin; Catalase; Chemical and Drug Induced Liver Injury; gamma-Glutamyltransferase; Globulins; Glutathione; Lipid Peroxidation; Liver; Male; Protective Agents; Rats, Sprague-Dawley; Rats, Wistar; Serum Albumin; Superoxide Dismutase | 2021 |
Prevalence, severity, duration and resolution of cholestasis after acute liver failure.
Topics: Acetaminophen; Adult; Alkaline Phosphatase; Bilirubin; Cholestasis; gamma-Glutamyltransferase; Humans; Liver Failure, Acute; Prevalence | 2022 |
Acetaminophen administration leads to unexpected high unbound bilirubin levels.
Topics: Acetaminophen; Bilirubin; Humans; Infant, Newborn; Jaundice, Neonatal | 2022 |
Galium aparine L. protects against acetaminophen-induced hepatotoxicity in rats.
Topics: Acetaminophen; Alanine Transaminase; Animals; Anti-Anxiety Agents; Aspartate Aminotransferases; Bilirubin; Chemical and Drug Induced Liver Injury; Galium; Hepatic Encephalopathy; Liver; Plant Extracts; Rats; Rats, Wistar | 2022 |
Nilotinib alleviated acetaminophen-induced acute hepatic injury in mice through inhibiting HIF-1alpha/VEGF-signaling pathway.
Topics: Acetaminophen; Animals; Bilirubin; Chemical and Drug Induced Liver Injury; Liver; Male; Mice; Oxidative Stress; Signal Transduction; Superoxide Dismutase; Vascular Endothelial Growth Factor A | 2022 |
GC-MS analysis, and evaluation of protective effect of Piper chaba stem bark against paracetamol-induced liver damage in Sprague-Dawley rats: Possible defensive mechanism by targeting CYP2E1 enzyme through in silico study.
Topics: Acetaminophen; Alkaloids; Animals; Bilirubin; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Esters; Fatty Acids; Gas Chromatography-Mass Spectrometry; Lipids; Liver; Methanol; Piper; Plant Bark; Plant Extracts; Rats; Rats, Sprague-Dawley; Serum Albumin; Silymarin | 2022 |
[Schisandrin C improves acetaminophen-induced liver injury in mice by regulating Nrf2 signaling pathway].
Topics: Acetaminophen; Animals; Bilirubin; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Liver; Mice; NF-E2-Related Factor 2; Oxidative Stress; Signal Transduction | 2022 |
Fluctuations in unbound bilirubin levels during acetaminophen therapy for patent ductus arteriosus.
Topics: Acetaminophen; Bilirubin; Ductus Arteriosus, Patent; Humans; Infant, Newborn; Infant, Premature; Persistent Fetal Circulation Syndrome | 2023 |
Hepatoprotective effect of methanol extract of Agave americana leaves on paracetamol induced hepatotoxicity in Wistar albino rats.
Topics: Acetaminophen; Agave; Animals; Bilirubin; Chemical and Drug Induced Liver Injury; Gum Arabic; Methanol; Plant Extracts; Rats; Rats, Wistar; Silymarin | 2023 |
A Biomimetic Nanoparticle Exerting Protection against Acute Liver Failure by Suppressing CYP2E1 Activity and Scavenging Excessive ROS.
Topics: Acetaminophen; Animals; Bilirubin; Biomimetics; Cytochrome P-450 CYP2E1; Glutathione; Liver; Liver Failure, Acute; Mice; Reactive Oxygen Species | 2023 |
Pharmacokinetics and safety of prolonged paracetamol treatment in neonates: An interventional cohort study.
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Bilirubin; Cohort Studies; Humans; Infant; Infant, Newborn; Pain | 2023 |
Isolation and characterization of bioactive components from hydroalcoholic extract of Cymbopogon jwarancusa (Jones) Schult. to evaluate its hepatoprotective activity.
Topics: Acetaminophen; Animals; Antioxidants; Bilirubin; Chemical and Drug Induced Liver Injury; Cymbopogon; Liver; Phenols; Plant Extracts; Rats; Rats, Wistar; Silymarin; Terpenes | 2024 |