Compounds > acetaminophen

acetaminophen and atorvastatin

acetaminophen has been researched along with atorvastatin in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (35.71)29.6817
2010's8 (57.14)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Buckley, DB; Funk, RS; Hensley, T; Kazmi, F; Loewen, GJ; Parkinson, A; Pope, C1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brain, RA; Hanson, ML; Johnson, DJ; Lam, MW; Mabury, SA; Richards, SM; Sanderson, H; Sibley, PK; Solomon, KR; Young, C1
Alon, US; Haney, CJ; Srivastava, T1
Barceló, D; Jelić, A; Petrović, M1
Farag, MM; Mohamed, MB; Youssef, EA1
Deng, H; Hou, Z; Ju, L; Li, Y; Wang, L; Wang, Y; Xie, J; Zhang, Y; Zhang, Z1
Ala, S; Alvandipour, M; Faramarzi, F; Hamidian, M; Rahmani, N; Saeedi, M; Shiva, A1
Kristensen, K; Langeskov, EK1

Reviews

1 review(s) available for acetaminophen and atorvastatin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for acetaminophen and atorvastatin

ArticleYear
Atorvastatin may have no effect on acute phase reaction in children after intravenous bisphosphonate infusion.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2009, Volume: 24, Issue:2

    Topics: Acetaminophen; Acute-Phase Reaction; Anticholesteremic Agents; Atorvastatin; Bone Density Conservation Agents; C-Reactive Protein; Child; Diphosphonates; Female; Heptanoic Acids; Humans; Infusions, Intravenous; Male; Oxycodone; Pain; Placebos; Pyrroles

2009
Effects of Topical Atorvastatin (2 %) on Posthemorrhoidectomy Pain and Wound Healing: A Randomized Double-Blind Placebo-Controlled Clinical Trial.
    World journal of surgery, 2017, Volume: 41, Issue:2

    Topics: Acetaminophen; Administration, Topical; Adult; Aged; Analgesics, Opioid; Atorvastatin; Defecation; Double-Blind Method; Female; Gels; Hemorrhoidectomy; Hemorrhoids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Meperidine; Middle Aged; Pain Measurement; Pain, Postoperative; Prospective Studies; Wound Healing; Young Adult

2017

Other Studies

11 other study(ies) available for acetaminophen and atorvastatin

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Glutathione; Pharmacology; Sulfur Radioisotopes

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Lysosomal sequestration (trapping) of lipophilic amine (cationic amphiphilic) drugs in immortalized human hepatocytes (Fa2N-4 cells).
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:4

    Topics: Adrenergic beta-Antagonists; Amines; Ammonium Chloride; Antidepressive Agents, Tricyclic; Atorvastatin; Cell Line, Transformed; Diuretics; Hepatocytes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imipramine; Lysosomes; Monensin; Nigericin; Propranolol; Pyrroles

2013
Microcosm evaluation of the effects of an eight pharmaceutical mixture to the aquatic macrophytes Lemna gibba and Myriophyllum sibiricum.
    Aquatic toxicology (Amsterdam, Netherlands), 2004, Oct-18, Volume: 70, Issue:1

    Topics: Acetaminophen; Analysis of Variance; Atorvastatin; Biological Assay; Biomass; Caffeine; Carbamazepine; Complex Mixtures; Dose-Response Relationship, Drug; Heptanoic Acids; Heterocyclic Compounds; Levofloxacin; Magnoliopsida; Ofloxacin; Pharmaceutical Solutions; Pyrroles; Sertraline; Sulfamethoxazole; Toxicity Tests; Trimethoprim; Water Pollutants, Chemical

2004
Multi-residue method for trace level determination of pharmaceuticals in solid samples using pressurized liquid extraction followed by liquid chromatography/quadrupole-linear ion trap mass spectrometry.
    Talanta, 2009, Nov-15, Volume: 80, Issue:1

    Topics: Acetaminophen; Atorvastatin; Chromatography, Liquid; Diclofenac; Geologic Sediments; Heptanoic Acids; Hot Temperature; Hydrochlorothiazide; Ibuprofen; Pharmaceutical Preparations; Pyrroles; Reference Standards; Reproducibility of Results; Rivers; Sewage; Solid Phase Extraction; Tandem Mass Spectrometry

2009
Assessment of hepatic function, oxidant/antioxidant status, and histopathological changes in rats treated with atorvastatin: Effect of dose and acute intoxication with acetaminophen.
    Human & experimental toxicology, 2015, Volume: 34, Issue:8

    Topics: Acetaminophen; Animals; Antioxidants; Atorvastatin; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Liver Function Tests; Oxidants; Rats

2015
A Systematic Strategy for Screening and Application of Specific Biomarkers in Hepatotoxicity Using Metabolomics Combined With ROC Curves and SVMs.
    Toxicological sciences : an official journal of the Society of Toxicology, 2016, Volume: 150, Issue:2

    Topics: Acetaminophen; Animals; Atorvastatin; Biomarkers; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Liver; Male; Metabolomics; Rats, Wistar; ROC Curve; Sensitivity and Specificity; Support Vector Machine

2016
Population pharmacokinetic of paracetamol and atorvastatin with co-administration of semaglutide.
    Pharmacology research & perspectives, 2022, Volume: 10, Issue:4

    Topics: Acetaminophen; Atorvastatin; Diabetes Mellitus, Type 2; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Humans; Hypoglycemic Agents

2022