acetaminophen has been researched along with arachidonic acid in 41 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (51.22) | 18.7374 |
| 1990's | 4 (9.76) | 18.2507 |
| 2000's | 9 (21.95) | 29.6817 |
| 2010's | 6 (14.63) | 24.3611 |
| 2020's | 1 (2.44) | 2.80 |
| Authors | Studies |
|---|---|
| Friesen, RW; Mancini, JA | 1 |
| Cheung, DT; Cobble, S; Nimni, ME; Schonfeld, SE; Yazdi, M | 1 |
| Egan, RW; Gale, PH; Harvison, PJ; Nelson, SD | 1 |
| Hinson, JA; Potter, DW | 1 |
| Wallenstein, MC | 1 |
| Kantor, TG | 1 |
| Christian, GD; Egan, RW; Gale, PH; Harvison, PJ; Hill, BS; Nelson, SD | 1 |
| Ivey, KJ; Krause, WJ; Razandi, M; Romano, M; Sekhon, S | 1 |
| Bernard, H; Boisseau, MR; Casadebaig, F; Dupin, JP; Gravier, D | 1 |
| Delbridge, L; Handelsman, DJ; McLennan, S; Reeve, T; Turtle, JR; Yue, DK | 1 |
| Kao, KJ; Pizzo, SV; Rauckman, EJ; Rosen, GM; Shorr, RI | 1 |
| Berlin, T; Larsson, R; Moldéus, P; Olsson, LI; Ross, D | 1 |
| Bach, PH; Bridges, JW | 2 |
| Baumann, J; von Bruchhausen, F; Wurm, G | 1 |
| Capetola, RJ; Fuller, BL; Levinson, SL; Marinan, BA; Rosenthale, ME; Tolman, EL | 1 |
| Laitinen, O; Seppälä, E; Vapaatalo, H | 1 |
| Cagen, LM; Malik, KU; Shaffer, JE | 1 |
| Boyd, JA; Eling, TE | 1 |
| Duggin, GG; Horvath, JS; Mohandas, J; Tiller, DJ | 2 |
| Andersson, B; Berggren, M; Moldéus, P; Rahimtula, A | 1 |
| Rao, GH; Reddy, KR; White, JG | 1 |
| Bhagat, K; Collier, J; Vallance, P | 1 |
| Evans, RJ; Hayes, LJ; Heath, MF; Littler, RM; McEvoy, RJ; Poole, AW | 1 |
| Capodici, C; Hanft, S; Kheterpal, N; Philips, MR; Pillinger, MH; Rosenthal, P; Weissmann, G | 1 |
| Aronoff, DM; Boutaud, O; Marnett, LJ; Oates, JA; Richardson, JH | 1 |
| Ajmone-Cat, MA; Greco, A; Minghetti, L; Nicolini, A; Sciulli, MG | 1 |
| Munsterhjelm, E; Niemi, TT; Rosenberg, PH; Silvanto, M; Ylikorkala, O | 1 |
| Alexander, JP; Andersson, DA; Basbaum, AI; Björk, H; Cravatt, BF; Ermund, A; Högestätt, ED; Jönsson, BA; Zygmunt, PM | 1 |
| Munsterhjelm, E; Neuvonen, PJ; Niemi, TT; Rosenberg, PH; Ylikorkala, O | 1 |
| Baber, SR; Hyman, AL; Kadowitz, PJ; Nazim, MM; Nossaman, BD; Waldron, PR | 1 |
| Anderson, BJ | 1 |
| Meneely, KM; Porubsky, PR; Scott, EE | 1 |
| Boutaud, O; Oates, JA | 1 |
| Kobzar, G; Mardla, V; Samel, N | 1 |
| Altavilla, D; Bitto, A; Burnett, BP; Levy, RM; Pillai, L; Squadrito, F | 1 |
| Dejucq-Rainsford, N; Desdoits-Lethimonier, C; Jégou, B; Kristensen, DM; Le Fol, V; Leffers, H; Lesné, L | 1 |
| Amin, T; Bokiej, M; Boutaud, O; Gruenberg, KC; Masterson, TS; Oates, JA; Roberts, LJ; Shi, Q; Vergeade, A; Yin, H; Ying, W; Zackert, WE; Zinkel, SS | 1 |
| Cap, AP; Dubick, MA; Martini, AK; Martini, WZ; Rodriguez, CM | 1 |
| Bae, SJ; Bak, SB; Kim, YW | 1 |
2 review(s) available for acetaminophen and arachidonic acid
| Article | Year |
|---|---|
Chemically induced renal papillary necrosis and upper urothelial carcinoma. Part 1.
Topics: Acetaminophen; Aged; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Aspirin; Carbohydrate Metabolism; Female; Glycosaminoglycans; Hemodynamics; Humans; Kidney Medulla; Kidney Papillary Necrosis; Lipid Metabolism; Male; Middle Aged; Nephrons; Phenacetin; Renal Circulation; Urinary Bladder Neoplasms | 1985 |
Paracetamol (Acetaminophen): mechanisms of action.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Arachidonic Acid; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Humans; Nitric Oxide; Nociceptors; Peroxidase; Prostaglandin H2; Prostaglandin-Endoperoxide Synthases; Receptors, Cannabinoid; Receptors, Prostaglandin | 2008 |
1 trial(s) available for acetaminophen and arachidonic acid
| Article | Year |
|---|---|
Influence on platelet aggregation of i.v. parecoxib and acetaminophen in healthy volunteers.
Topics: Acetaminophen; Adenosine Diphosphate; Adult; Analgesics, Non-Narcotic; Arachidonic Acid; Blood Platelets; Cross-Over Studies; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Interactions; Epinephrine; Humans; Infusions, Intravenous; Isoxazoles; Male; Platelet Aggregation; Thromboxane B2 | 2006 |
38 other study(ies) available for acetaminophen and arachidonic acid
| Article | Year |
|---|---|
Microsomal prostaglandin E2 synthase-1 (mPGES-1): a novel anti-inflammatory therapeutic target.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Atherosclerosis; Fever; Humans; Intramolecular Oxidoreductases; Mice; Mice, Knockout; Microsomes; Pain; Prostaglandin-E Synthases; Stroke | 2008 |
Effects of non-steroidal anti-inflammatory drugs on demineralized bone-induced bone formation.
Topics: Acetaminophen; Alkaline Phosphatase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Bone Matrix; Flurbiprofen; Indomethacin; Male; Osteogenesis; Piroxicam; Rats | 1992 |
Acetaminophen as a cosubstrate and inhibitor of prostaglandin H synthase.
Topics: Acetaminophen; Animals; Arachidonic Acid; Arachidonic Acids; Carbon Radioisotopes; Cyclooxygenase Inhibitors; Kinetics; Male; Microsomes; Prostaglandin-Endoperoxide Synthases; Seminal Vesicles; Sheep; Structure-Activity Relationship | 1986 |
The 1- and 2-electron oxidation of acetaminophen catalyzed by prostaglandin H synthase.
Topics: Acetaminophen; Animals; Arachidonic Acid; Arachidonic Acids; Benzoquinones; Glutathione; Imines; Kinetics; Macromolecular Substances; Male; Microsomes; Oxidation-Reduction; Prostaglandin-Endoperoxide Synthases; Seminal Vesicles; Sheep | 1987 |
Attenuation of penicillin models of epilepsy by nonsteroidal anti-inflammatory drugs.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Brain; Cyclooxygenase Inhibitors; Disease Models, Animal; Epilepsy; Female; Ibuprofen; Mefenamic Acid; Penicillins; Prostaglandins; Rats; Rats, Inbred Strains; Thromboxanes | 1987 |
Current modalities in arthritic diseases.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Arthritis; Aspirin; Humans; Inflammation; Pain; Prostaglandin-Endoperoxide Synthases | 1987 |
Acetaminophen and analogs as cosubstrates and inhibitors of prostaglandin H synthase.
Topics: Acetaminophen; Animals; Arachidonic Acid; Arachidonic Acids; Ascorbic Acid; Benzoquinones; Butylated Hydroxyanisole; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Glutathione; Imines; Indomethacin; Male; Prostaglandin-Endoperoxide Synthases; Prostaglandins G; Seminal Vesicles; Sheep | 1988 |
Human cell line for study of damage to gastric epithelial cells in vitro.
Topics: Acetaminophen; Arachidonic Acid; Arachidonic Acids; Cell Line; Cell Survival; Chromosomes; Gastric Mucosa; Histocytochemistry; Humans; Immunohistochemistry; Indomethacin; Isoenzymes; Microscopy, Electron; Phenotype; Ploidies; Prostaglandins; Taurocholic Acid | 1988 |
In vitro antiaggregant activity of paracetamol and derivatives.
Topics: Acetaminophen; Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Serotonin; Stereoisomerism; Structure-Activity Relationship; Thromboxane B2 | 1988 |
The effects of cyclooxygenase and lipoxygenase inhibitors on the collagen abnormalities of diabetic rats.
Topics: Acetaminophen; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Female; Indomethacin; Lipoxygenase Inhibitors; Naproxen; Rats; Rats, Inbred Strains | 1985 |
In vitro effects of acetaminophen and its analogues on human platelet aggregation and thromboxane B2 synthesis.
Topics: Acetaminophen; Arachidonic Acid; Arachidonic Acids; Humans; Platelet Aggregation; Serotonin; Thromboxane B2; Thromboxanes | 1985 |
Prostaglandin synthase catalyzed metabolic activation of p-phenetidine and acetaminophen by microsomes isolated from rabbit and human kidney.
Topics: Acetaminophen; Aminophenols; Animals; Arachidonic Acid; Arachidonic Acids; Glutathione; Glutathione Disulfide; Humans; Indomethacin; Kidney; Kinetics; Linolenic Acids; Lipid Peroxides; Male; Metyrapone; Microsomes; Models, Chemical; NADP; Phenetidine; Proadifen; Prostaglandin-Endoperoxide Synthases; Protein Binding; Rabbits | 1985 |
Decreasing inhibitory potency of prostaglandin synthetase inhibitors during their cooxidative metabolism. Studies on aminophenols, pyrazolon derivatives and 1,3-diphenylisobenzofuran.
Topics: Acetaminophen; Aminophenols; Aminopyrine; Animals; Arachidonic Acid; Arachidonic Acids; Benzofurans; Cyclooxygenase Inhibitors; Diclofenac; Indomethacin; Kidney Medulla; Lipoxygenase Inhibitors; Male; Peroxides; Phenacetin; Phenylbutazone; Rats; Rats, Inbred Strains | 1983 |
Tissue selectivity and variability of effects of acetaminophen on arachidonic acid metabolism.
Topics: Acetaminophen; Animals; Arachidonic Acid; Arachidonic Acids; Cerebral Cortex; Female; Guinea Pigs; In Vitro Techniques; Kidney; Lung; Male; Organ Specificity; Prostaglandins; Rats; Rats, Inbred Strains; Stomach | 1983 |
Comparative study on the effects of acetylsalicylic acid, indomethacin and paracetamol on metabolites of arachidonic acid in plasma, serum and urine in man.
Topics: Acetaminophen; Arachidonic Acid; Arachidonic Acids; Aspirin; Dinoprostone; Humans; Indomethacin; Prostaglandins E; Thromboxane B2 | 1983 |
The role of metabolic activation of analgesics and non-steroidal anti-inflammatory drugs in the development of renal papillary necrosis and upper urothelial carcinoma.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Aspirin; Biotransformation; Drug Synergism; Humans; Kidney; Necrosis; Peroxidases; Urinary Bladder Neoplasms | 1984 |
Attenuation by acetaminophen or arachidonic acid-induced coronary vasodilation and output of prostaglandins in the isolated rat heart.
Topics: 6-Ketoprostaglandin F1 alpha; Acetaminophen; Animals; Arachidonic Acid; Arachidonic Acids; Heart; In Vitro Techniques; Male; Perfusion; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats; Vasodilation | 1981 |
Prostaglandin endoperoxide synthetase-dependent cooxidation of acetaminophen to intermediates which covalently bind in vitro to rabbit renal medullary microsomes.
Topics: Acetaminophen; Animals; Arachidonic Acid; Arachidonic Acids; Benzene Derivatives; In Vitro Techniques; Kidney Medulla; Male; Microsomes; Oxidation-Reduction; Peroxides; Prostaglandin-Endoperoxide Synthases; Rabbits; Seminal Vesicles; Sheep | 1981 |
Regional differences in peroxidatic activation of paracetamol (acetaminophen) mediated by cytochrome P450 and prostaglandin endoperoxide synthetase in rabbit kidney.
Topics: Acetaminophen; Animals; Arachidonic Acid; Arachidonic Acids; Biotransformation; Cytochrome P-450 Enzyme System; Hot Temperature; In Vitro Techniques; Kidney; Male; Methemoglobin; Organ Specificity; Peroxides; Prostaglandin-Endoperoxide Synthases; Protein Denaturation; Rabbits | 1981 |
Metabolic oxidation of acetaminophen (paracetamol) mediated by cytochrome P-450 mixed-function oxidase and prostaglandin endoperoxide synthetase in rabbit kidney.
Topics: Acetaminophen; Animals; Arachidonic Acid; Arachidonic Acids; Cytochrome P-450 Enzyme System; Kidney; Male; Microsomes; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Oxidoreductases; Prostaglandin-Endoperoxide Synthases; Rabbits; Substrate Specificity | 1981 |
Prostaglandin synthetase catalyzed activation of paracetamol.
Topics: Acetaminophen; Animals; Arachidonic Acid; Arachidonic Acids; Biotransformation; Glutathione; Indomethacin; Kidney; Kinetics; Male; Microsomes; Prostaglandin-Endoperoxide Synthases; Rats; Seminal Vesicles; Sheep | 1981 |
Effect of acetaminophen and salicylate on aspirin-induced inhibition of human platelet cyclo-oxygenase.
Topics: Acetaminophen; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Humans; Salicylates; Thromboxane B2 | 1982 |
Vasodilatation to arachidonic acid in humans. An insight into endogenous prostanoids and effects of aspirin.
Topics: Acetaminophen; Adult; Arachidonic Acid; Aspirin; Bradykinin; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; Hand; Humans; Male; Nitroglycerin; Prostaglandins; Reproducibility of Results; Time Factors; Vasodilation; Veins | 1995 |
The effects of aspirin and paracetamol on the aggregation of equine blood platelets.
Topics: Acetaminophen; Adenosine Diphosphate; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Cell Size; Collagen; Dose-Response Relationship, Drug; Horses; In Vitro Techniques; Nephelometry and Turbidimetry; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Thromboxane A2 | 1994 |
Modes of action of aspirin-like drugs: salicylates inhibit erk activation and integrin-dependent neutrophil adhesion.
Topics: Acetaminophen; Antigens, CD; Arachidonic Acid; Aspirin; Calcium-Calmodulin-Dependent Protein Kinases; CD18 Antigens; Cell Adhesion; Cell Aggregation; Cell Survival; Cyclooxygenase Inhibitors; Humans; In Vitro Techniques; Macrophage-1 Antigen; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Sodium Salicylate; Tetradecanoylphorbol Acetate | 1998 |
Determinants of the cellular specificity of acetaminophen as an inhibitor of prostaglandin H(2) synthases.
Topics: 6-Ketoprostaglandin F1 alpha; Acetaminophen; Analgesics, Non-Narcotic; Arachidonic Acid; Blood Platelets; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dinoprostone; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Hydrogen Peroxide; Interleukin-1; Intramolecular Oxidoreductases; Isoenzymes; Lipid Peroxidation; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Prostaglandins G; Substrate Specificity; Umbilical Veins | 2002 |
Paracetamol effectively reduces prostaglandin E2 synthesis in brain macrophages by inhibiting enzymatic activity of cyclooxygenase but not phospholipase and prostaglandin E synthase.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Blotting, Western; Cells, Cultured; Cerebral Cortex; Dinoprostone; Intramolecular Oxidoreductases; Microglia; Nitric Oxide; Phospholipases; Prostaglandin-E Synthases; Prostaglandin-Endoperoxide Synthases; Rats; Tumor Necrosis Factor-alpha | 2003 |
Characterization of inhibition of platelet function by paracetamol and its interaction with diclofenac in vitro.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; In Vitro Techniques; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prostaglandin-Endoperoxide Synthases; Thromboxane B2 | 2005 |
Conversion of acetaminophen to the bioactive N-acylphenolamine AM404 via fatty acid amide hydrolase-dependent arachidonic acid conjugation in the nervous system.
Topics: Acetaminophen; Amidohydrolases; Aminophenols; Animals; Arachidonic Acid; Arachidonic Acids; Brain; Cell Line; Central Nervous System; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Female; Ganglia, Spinal; Macrophages; Membrane Proteins; Mice; Mice, Knockout; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar | 2005 |
Acetaminophen, phenacetin and dipyrone do not modulate pressor responses to arachidonic Acid or to pressor agents.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Blood Pressure; Cyclooxygenase 2 Inhibitors; Dipyrone; Phenacetin; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides | 2007 |
Structures of human cytochrome P-450 2E1. Insights into the binding of inhibitors and both small molecular weight and fatty acid substrates.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Arachidonic Acid; Carcinogens; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Enzyme Inhibitors; Heme; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Hydroxylation; Imidazoles; Models, Molecular; Nitrosamines; Protein Structure, Secondary; Smoking; Xenobiotics | 2008 |
Study of inhibitors of the PGH synthases for which potency is regulated by the redox state of the enzymes.
Topics: Acetaminophen; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Cell Line, Tumor; Cyclooxygenase Inhibitors; Dinoprostone; Gas Chromatography-Mass Spectrometry; Humans; Hydrogen Peroxide; Mice; Oxidation-Reduction; Prostaglandin-Endoperoxide Synthases; Salicylic Acid; Thromboxane B2 | 2010 |
Short-term exposure of platelets to glucose impairs inhibition of platelet aggregation by cyclooxygenase inhibitors.
Topics: Acetaminophen; Adenosine Diphosphate; Adult; Arachidonic Acid; Aspirin; Blood Platelets; Cells, Cultured; Collagen; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; Glucose; Humans; Indomethacin; Lactic Acid; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet-Rich Plasma | 2011 |
Flavocoxid inhibits phospholipase A2, peroxidase moieties of the cyclooxygenases (COX), and 5-lipoxygenase, modifies COX-2 gene expression, and acts as an antioxidant.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Catechin; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Combinations; Gene Expression Regulation, Enzymologic; Ibuprofen; In Vitro Techniques; Lipoxygenase Inhibitors; Macrophages, Peritoneal; Male; Membrane Proteins; Osteoarthritis; Peroxidases; Phospholipase A2 Inhibitors; Phospholipases A2; Rats; Rats, Sprague-Dawley | 2011 |
Paracetamol (acetaminophen), aspirin (acetylsalicylic acid) and indomethacin are anti-androgenic in the rat foetal testis.
Topics: Acetaminophen; Androgen Antagonists; Animals; Arachidonic Acid; Aspirin; Cryptorchidism; Endocrine Disruptors; Female; Indomethacin; Male; Pregnancy; Prostaglandin D2; Rats; Testis; Testosterone | 2012 |
Acetaminophen inhibits cytochrome c redox cycling induced lipid peroxidation.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Arachidonic Acid; Cardiolipins; Catalysis; Cytochromes c; Fatty Acids, Unsaturated; Humans; Lipid Peroxidation; Mitochondria; Oxidation-Reduction | 2012 |
Acetaminophen and meloxicam inhibit platelet aggregation and coagulation in blood samples from humans.
Topics: Acetaminophen; Arachidonic Acid; Blood Cells; Blood Coagulation; Blood Specimen Collection; Cells, Cultured; Collagen; Dose-Response Relationship, Drug; Humans; Meloxicam; Partial Thromboplastin Time; Platelet Aggregation; Prothrombin Time; Thiazines; Thiazoles; Thrombelastography | 2014 |
Coordination of AMPK and YAP by
Topics: Acetaminophen; AMP-Activated Protein Kinases; Animals; Antioxidants; Arachidonic Acid; Iron; Mice; Reactive Oxygen Species | 2022 |