acetaminophen and amodiaquine

acetaminophen has been researched along with amodiaquine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (37.50)29.6817
2010's5 (62.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Buckley, DB; Funk, RS; Hensley, T; Kazmi, F; Loewen, GJ; Parkinson, A; Pope, C1
Commandeur, JN; Damsten, MC; Maasdijk, DM; van Vugt-Lussenburg, BM; Vermeulen, NP1
Fitch, WL; Wen, B1
Hayen, H; Karst, U; Lohmann, W1
Barcellini-Couget, S; de Sousa, G; Luzy, AP; Peyre, L; Rahmani, R; Zucchini-Pascal, N1

Other Studies

8 other study(ies) available for acetaminophen and amodiaquine

ArticleYear
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Glutathione; Pharmacology; Sulfur Radioisotopes

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
Lysosomal sequestration (trapping) of lipophilic amine (cationic amphiphilic) drugs in immortalized human hepatocytes (Fa2N-4 cells).
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:4

    Topics: Adrenergic beta-Antagonists; Amines; Ammonium Chloride; Antidepressive Agents, Tricyclic; Atorvastatin; Cell Line, Transformed; Diuretics; Hepatocytes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imipramine; Lysosomes; Monensin; Nigericin; Propranolol; Pyrroles

2013
Heterotropic and homotropic cooperativity by a drug-metabolising mutant of cytochrome P450 BM3.
    Biochemical and biophysical research communications, 2006, Aug-04, Volume: 346, Issue:3

    Topics: Acetaminophen; Amodiaquine; Arginine; Benzoflavones; Caffeine; Cytochrome P-450 Enzyme System; Dextromethorphan; Enzyme Activation; Humans; Kinetics; Leucine; Molecular Structure; Mutation; N-Methyl-3,4-methylenedioxyamphetamine; Pharmaceutical Preparations; Phenylalanine; Substrate Specificity

2006
Screening and characterization of reactive metabolites using glutathione ethyl ester in combination with Q-trap mass spectrometry.
    Journal of mass spectrometry : JMS, 2009, Volume: 44, Issue:1

    Topics: Acetaminophen; Amodiaquine; Carbamazepine; Glutathione; Humans; Imipramine; Mass Spectrometry; Metabolomics; Microsomes, Liver; Phenols; Reproducibility of Results; Sensitivity and Specificity; Ticlopidine

2009
Covalent protein modification by reactive drug metabolites using online electrochemistry/liquid chromatography/mass spectrometry.
    Analytical chemistry, 2008, Dec-15, Volume: 80, Issue:24

    Topics: Acetaminophen; Amodiaquine; Chromatography, Liquid; Clozapine; Electrochemistry; Humans; Lactoglobulins; Mass Spectrometry; Serum Albumin; Spectroscopy, Fourier Transform Infrared

2008
High-content screening imaging and real-time cellular impedance monitoring for the assessment of chemical's bio-activation with regards hepatotoxicity.
    Toxicology in vitro : an international journal published in association with BIBRA, 2015, Volume: 29, Issue:7

    Topics: Acetaminophen; Amodiaquine; Animals; Carbamazepine; Cell Line, Tumor; Cell Survival; Cells, Cultured; Chemical and Drug Induced Liver Injury; Diethylstilbestrol; Erythromycin; Furosemide; Hepatocytes; High-Throughput Screening Assays; Male; Neutral Red; Rats; Toxicity Tests; Tretinoin

2015