acetaminophen has been researched along with am 404 in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (40.00) | 29.6817 |
| 2010's | 6 (40.00) | 24.3611 |
| 2020's | 3 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Coste, O; Di Marzo, V; Imming, P; Ligresti, A; Nüsing, RM; Ott, I; Sinning, C; Watzer, B | 1 |
| Å Nilsson, JL; Blomgren, A; Blomqvist, A; Boudieu, L; Eschalier, A; Grundemar, L; Mallet, C; Nilsson, UJ; Shionoya, K; Sundin, AP; Zygmunt, PM | 1 |
| Alexander, JP; Andersson, DA; Basbaum, AI; Björk, H; Cravatt, BF; Ermund, A; Högestätt, ED; Jönsson, BA; Zygmunt, PM | 1 |
| Appendino, G; Caballero, FJ; Fiebich, BL; Hess, S; Macho, A; Muñoz, E; Navarrete, CM; Sancho, R | 1 |
| Beaulieu, P; Dani, M; Guindon, J; Lambert, C | 1 |
| Pini, LA; Ruggieri, V; Sandrini, M; Vitale, G | 1 |
| Ashton, J | 1 |
| Ayoub, SS; Baker, D; Bolton, C; Flower, RJ; Pryce, G; Seed, MP | 1 |
| Abou-El-Ela, SH; El-Wakeil, AF; Zaitone, SA | 1 |
| Manna, SS; Umathe, SN | 1 |
| Marjakangas, JM; Overheul, GJ; Thomassen, MC; van Cleef, KW; van Rij, RP | 1 |
| de Oliveira, ACP; Ditrich, J; Fiebich, BL; Fortwängler, E; Marcotegui, AR; Muñoz, E; Perazzo, JC; Saliba, SW | 1 |
| Eberhardt, M; Hage, A; Jangra, A; Leffler, A; Meyer, S; Stueber, T | 1 |
| Komatsu, S; Nakamura, S; Nonaka, T; Yamada, T; Yamamoto, T | 1 |
| Chaker, J; David, A; Frederiksen, H; Juul, A; Kristensen, DM; Nielsen, BS; Nielsen, JE; Rasmussen, RH; Rehfeld, A; Skakkebæk, NE | 1 |
15 other study(ies) available for acetaminophen and am 404
| Article | Year |
|---|---|
New analgesics synthetically derived from the paracetamol metabolite N-(4-hydroxyphenyl)-(5Z,8Z,11Z,14Z)-icosatetra-5,8,11,14-enamide.
Topics: Acetaminophen; Amidohydrolases; Analgesics; Animals; Arachidonic Acids; Brain; Formaldehyde; Humans; Inhibitory Concentration 50; Kinetics; Mice; Models, Chemical; Prostaglandin-Endoperoxide Synthases; Rats; Receptors, Cannabinoid | 2008 |
Paracetamol analogues conjugated by FAAH induce TRPV1-mediated antinociception without causing acute liver toxicity.
Topics: Acetaminophen; Amidohydrolases; Aminophenols; Analgesics; Animals; Antipyretics; Arachidonic Acids; Brain; Female; Humans; Indazoles; Liver; Male; Mice, Inbred C57BL; Models, Molecular; Pain; Pain Measurement; Prostaglandin-Endoperoxide Synthases; Rats, Wistar; Structure-Activity Relationship; Transient Receptor Potential Channels; TRPV Cation Channels | 2021 |
Conversion of acetaminophen to the bioactive N-acylphenolamine AM404 via fatty acid amide hydrolase-dependent arachidonic acid conjugation in the nervous system.
Topics: Acetaminophen; Amidohydrolases; Aminophenols; Animals; Arachidonic Acid; Arachidonic Acids; Brain; Cell Line; Central Nervous System; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Female; Ganglia, Spinal; Macrophages; Membrane Proteins; Mice; Mice, Knockout; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar | 2005 |
The acetaminophen-derived bioactive N-acylphenolamine AM404 inhibits NFAT by targeting nuclear regulatory events.
Topics: Acetaminophen; Arachidonic Acids; Humans; Jurkat Cells; NFATC Transcription Factors; Nuclear Proteins; Transcription Factor AP-1; Transcription, Genetic | 2007 |
The local antinociceptive effects of paracetamol in neuropathic pain are mediated by cannabinoid receptors.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Arachidonic Acids; Cannabinoid Receptor Antagonists; Disease Models, Animal; Dose-Response Relationship, Drug; Hindlimb; Hot Temperature; Hyperalgesia; Indoles; Male; Neuralgia; Pain Measurement; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Sciatic Nerve | 2007 |
Differential involvement of opioidergic and serotonergic systems in the antinociceptive activity of N-arachidonoyl-phenolamine (AM404) in the rat: comparison with paracetamol.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Arachidonic Acids; Frontal Lobe; Hydroxyindoleacetic Acid; Male; Pain; Pain Measurement; Pons; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Opioid, kappa; Receptors, Opioid, mu; Receptors, Serotonin, 5-HT2; Receptors, Serotonin, 5-HT3; Serotonin | 2008 |
Pro-drugs for indirect cannabinoids as therapeutic agents.
Topics: Acetaminophen; Amidohydrolases; Animals; Arachidonic Acids; Cannabinoids; Dronabinol; Humans; Pain; Prodrugs | 2008 |
Paracetamol-induced hypothermia is independent of cannabinoids and transient receptor potential vanilloid-1 and is not mediated by AM404.
Topics: Acetaminophen; Amidohydrolases; Anilides; Animals; Arachidonic Acids; Cannabinoids; Cinnamates; Hypothermia; Hypothermia, Induced; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; TRPV Cation Channels | 2011 |
Inhibition of fatty acid amide hydrolase by URB597 attenuates the anxiolytic-like effect of acetaminophen in the mouse elevated plus-maze test.
Topics: Acetaminophen; Amidohydrolases; Animals; Anti-Anxiety Agents; Anxiety; Arachidonic Acids; Benzamides; Carbamates; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Maze Learning; Mice; Mice, Inbred BALB C; Motor Activity; Piperidines; Pyrazoles; Rimonabant | 2012 |
Paracetamol potentiates the antidepressant-like and anticompulsive-like effects of fluoxetine.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Arachidonic Acids; Compulsive Behavior; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Endocannabinoids; Fluoxetine; Male; Mice; Selective Serotonin Reuptake Inhibitors | 2015 |
Escape Mutations in NS4B Render Dengue Virus Insensitive to the Antiviral Activity of the Paracetamol Metabolite AM404.
Topics: Acetaminophen; Antiviral Agents; Arachidonic Acids; Biotransformation; Dengue Virus; Drug Resistance, Multiple, Viral; Gene Expression; Genes, Reporter; HeLa Cells; Humans; Luciferases; Microbial Sensitivity Tests; Mutation; Naltrexone; Ribavirin; Viral Nonstructural Proteins; Virus Replication | 2016 |
AM404, paracetamol metabolite, prevents prostaglandin synthesis in activated microglia by inhibiting COX activity.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Arachidonic Acids; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Mice; Mice, Inbred C57BL; Microglia; Prostaglandins; Rats; Rats, Sprague-Dawley | 2017 |
Activation of the capsaicin-receptor TRPV1 by the acetaminophen metabolite N-arachidonoylaminophenol results in cytotoxicity.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Animals; Arachidonic Acids; Benzoquinones; Capsaicin; Ganglia, Spinal; HEK293 Cells; Humans; Imines; Mice, Inbred C57BL; Neurons; Rabbits; Rats, Sprague-Dawley; Sensory System Agents; TRPV Cation Channels | 2018 |
Oral acetaminophen-induced spinal 5-hydroxytriyptamine release produces analgesic effects in the rat formalin test.
Topics: Acetaminophen; Administration, Oral; Analgesics; Animals; Arachidonic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Rats; Rats, Sprague-Dawley; Serotonin; Spine | 2022 |
Human sperm cells can form paracetamol metabolite AM404 that directly interferes with sperm calcium signalling and function through a CatSper-dependent mechanism.
Topics: Acetaminophen; Adult; Arachidonic Acids; Calcium; Calcium Channels; Humans; Male; Pharmaceutical Preparations; Progesterone; Sperm Motility; Spermatozoa | 2022 |