acetaminophen and acetaminophen mercapturate

acetaminophen has been researched along with acetaminophen mercapturate in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's1 (14.29)18.2507
2000's2 (28.57)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baillie, TA; Hoffmann, KJ1
Jollow, DJ; Miller, MG; Price, VF1
Corcoran, GB; Galinsky, RE1
Martin, U; Prescott, LF; Temple, RM; Winney, RJ1
Boos, J; Hempel, G; Koling, S; Lanvers, C; Würthwein, G1
Hickling, J; Kumara De Silva, R; Medlicott, NJ; Reith, D; Yang, L; Zacharias, M1
Böhlke, M; Ganetsky, M; Guatam, S; LeDuc, B; Pereira, L; Salhanick, SD; Williams, D1

Trials

2 trial(s) available for acetaminophen and acetaminophen mercapturate

ArticleYear
Monitoring paracetamol metabolism after single and repeated administration in pediatric patients with neoplastic diseases.
    International journal of clinical pharmacology and therapeutics, 2007, Volume: 45, Issue:9

    Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Antineoplastic Agents; Benzoquinones; Child; Child, Preschool; Cysteine; Drug Administration Schedule; Drug Interactions; Humans; Imines; Infant; Neoplasms; Oxidation-Reduction

2007
Effect of excipients on acetaminophen metabolism and its implications for prevention of liver injury.
    Journal of clinical pharmacology, 2013, Volume: 53, Issue:4

    Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Chemical and Drug Induced Liver Injury; Cross-Over Studies; Cytochrome P-450 CYP2E1 Inhibitors; Dosage Forms; Excipients; Female; Humans; Male; Propylene Glycol; Sulfates

2013

Other Studies

5 other study(ies) available for acetaminophen and acetaminophen mercapturate

ArticleYear
The use of alkoxycarbonyl derivatives for the mass spectral analysis of drug-thioether metabolites. Studies with the cysteine, mercapturic acid and glutathione conjugates of acetaminophen.
    Biomedical & environmental mass spectrometry, 1988, Jun-15, Volume: 15, Issue:12

    Topics: Acetaminophen; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Cysteine; Esters; Gas Chromatography-Mass Spectrometry; Indicators and Reagents; Mass Spectrometry

1988
Anomalous susceptibility of the fasted hamster to acetaminophen hepatotoxicity.
    Biochemical pharmacology, 1986, Mar-01, Volume: 35, Issue:5

    Topics: Acetaminophen; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cricetinae; Fasting; Glutathione; Liver Diseases; Necrosis; Time Factors

1986
Influence of advanced age on the formation and elimination of acetaminophen metabolites by male rats.
    Pharmacology, 1986, Volume: 32, Issue:6

    Topics: Acetaminophen; Aging; Animals; Biotransformation; Kinetics; Male; Rats; Rats, Inbred F344

1986
The disposition of paracetamol and its conjugates during multiple dosing in patients with end-stage renal failure maintained on haemodialysis.
    European journal of clinical pharmacology, 1993, Volume: 45, Issue:2

    Topics: Acetaminophen; Administration, Oral; Adult; Cysteine; Drug Administration Schedule; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis

1993
Simultaneous modelling of the Michaelis-Menten kinetics of paracetamol sulphation and glucuronidation.
    Clinical and experimental pharmacology & physiology, 2009, Volume: 36, Issue:1

    Topics: Acetaminophen; Adult; Chromatography, High Pressure Liquid; Cross-Over Studies; Cysteine; Dose-Response Relationship, Drug; Female; Humans; Male; Molecular Structure; Pain; Time; Young Adult

2009