acetaminophen has been researched along with acetaminophen cysteine in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (13.64) | 18.2507 |
| 2000's | 8 (36.36) | 29.6817 |
| 2010's | 10 (45.45) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Klaassen, CD; Madhu, C | 1 |
| Critchley, JA; Lau, GS | 1 |
| Martin, U; Prescott, LF; Temple, RM; Winney, RJ | 1 |
| Bruno, MK; Cohen, SD; Hennig, GE; Horton, RA; Roberts, JC; Stern, ST | 1 |
| Bruno, MK; Cohen, SD; Hill, DW; Horton, RA; Roberts, JC; Stern, ST | 1 |
| Chantharaksri, U; Fucharoen, P; Fucharoen, S; Howard, TA; Morales, NP; Sanvarinda, Y; Sirankapracha, P; Tankanitlert, J; Temsakulphong, A; Ware, RE | 1 |
| Alonso, EM; Davern, TJ; Hinson, JA; Hynan, LS; James, LP; Lee, WM; Squires, RH | 1 |
| Boos, J; Hempel, G; Koling, S; Lanvers, C; Würthwein, G | 1 |
| Bond, GR | 1 |
| Hickling, J; Kumara De Silva, R; Medlicott, NJ; Reith, D; Yang, L; Zacharias, M | 1 |
| Kim, SJ; Kim, SY; Kim, YC; Kwon, DY; Lee, MY | 1 |
| Claridge, LC | 1 |
| Dart, RC; Green, JL; Heard, KJ; James, LP; Judge, BS; Rhyee, S; Zolot, L | 1 |
| Bajt, ML; Jaeschke, H; Lebofsky, M; McGill, MR; Williams, CD | 1 |
| Bikin, DS; Curry, SC; Gerkin, RD; O'Connor, AD; Padilla-Jones, A; Rollins, DE; Ruha, AM; Slawson, MH; Wilkins, DG | 1 |
| Dart, RC; Frey, SM; Gorodetsky, RM; Green, JL; Heard, KJ; Wiegand, TJ; Wilkins, DG | 1 |
| Giraldo, P; Mizrahi, F; O'Malley, GF; O'Malley, RN; Rollins, D; Wilkins, D | 1 |
| Anderson, V; Bucher-Bartelson, B; Dart, RC; Green, JL; Heard, K | 1 |
| Boerma, D; Huisman, FW; Knibbe, CAJ; Peeters, MYM; Välitalo, PAJ; van den Anker, JN; van Dongen, EPA; van Ramshorst, B; van Rongen, A | 1 |
| Cheng, Y; Chowdhury, A; Jia, Z; Lu, J; Song, J; Sun, Y; Teng, T; Wang, H; Yin, X; Zhang, R; Zhu, Y | 1 |
| DU, Y; Liu, XF; Lu, YH; Tan, L; Wang, GJ; Wang, YX; Wu, X; Yang, FX; Zhang, JW; Zhou, F | 1 |
| Islam, A; Kahyo, T; Mamun, MA; Nabi, MM; Oyama, S; Rahman, MM; Sakamoto, T; Sato, T; Setou, M; Takahashi, Y | 1 |
1 review(s) available for acetaminophen and acetaminophen cysteine
| Article | Year |
|---|---|
Acetaminophen protein adducts: a review.
Topics: Acetaminophen; Animals; Cysteine; Humans; Liver; Protein Binding; Radioligand Assay | 2009 |
3 trial(s) available for acetaminophen and acetaminophen cysteine
| Article | Year |
|---|---|
Monitoring paracetamol metabolism after single and repeated administration in pediatric patients with neoplastic diseases.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Antineoplastic Agents; Benzoquinones; Child; Child, Preschool; Cysteine; Drug Administration Schedule; Drug Interactions; Humans; Imines; Infant; Neoplasms; Oxidation-Reduction | 2007 |
Acetaminophen-cysteine adducts during therapeutic dosing and following overdose.
Topics: Acetaminophen; Adolescent; Adult; Alcohol Drinking; Alcoholism; Biomarkers; Chemical and Drug Induced Liver Injury; Child; Cysteine; Dose-Response Relationship, Drug; Drug Overdose; Female; Humans; Male; Middle Aged; Young Adult | 2011 |
Paracetamol (acetaminophen) protein adduct concentrations during therapeutic dosing.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Biomarkers; Cysteine; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Young Adult | 2016 |
18 other study(ies) available for acetaminophen and acetaminophen cysteine
| Article | Year |
|---|---|
Protective effect of pregnenolone-16 alpha-carbonitrile on acetaminophen-induced hepatotoxicity in hamsters.
Topics: Acetaminophen; Alanine Transaminase; Animals; Biliary Tract; Cricetinae; Cysteine; Dipeptides; Dose-Response Relationship, Drug; Drug Interactions; L-Iditol 2-Dehydrogenase; Liver; Male; Mesocricetus; Pregnenolone Carbonitrile | 1991 |
The estimation of paracetamol and its major metabolites in both plasma and urine by a single high-performance liquid chromatography assay.
Topics: Acetaminophen; Chromatography, High Pressure Liquid; Cysteine; Humans; Spectrophotometry, Ultraviolet | 1994 |
The disposition of paracetamol and its conjugates during multiple dosing in patients with end-stage renal failure maintained on haemodialysis.
Topics: Acetaminophen; Administration, Oral; Adult; Cysteine; Drug Administration Schedule; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis | 1993 |
Contribution of acetaminophen-cysteine to acetaminophen nephrotoxicity in CD-1 mice: I. Enhancement of acetaminophen nephrotoxicity by acetaminophen-cysteine.
Topics: Acetaminophen; Animals; Cysteine; Dose-Response Relationship, Drug; Drug Synergism; Glutathione; Injections, Intraperitoneal; Injections, Subcutaneous; Kidney Cortex; Kidney Diseases; Liver; Male; Mice; Mice, Inbred Strains; Sulfhydryl Compounds; Toxicity Tests | 2005 |
Contribution of acetaminophen-cysteine to acetaminophen nephrotoxicity II. Possible involvement of the gamma-glutamyl cycle.
Topics: Acetaminophen; Animals; Cell Membrane; Chromatography, High Pressure Liquid; Cysteine; Dipeptides; Dose-Response Relationship, Drug; gamma-Glutamyltransferase; Glutathione; Glutathione Transferase; Injections, Intraperitoneal; Isoxazoles; Kidney Diseases; Kidney Tubules, Proximal; Male; Mass Spectrometry; Mice; Mice, Inbred Strains; Microvilli; Molecular Structure; Toxicity Tests | 2005 |
A pharmacokinetic study of paracetamol in Thai beta-thalassemia/HbE patients.
Topics: Acetaminophen; Adult; Area Under Curve; beta-Thalassemia; Bilirubin; Cysteine; Female; Glucuronosyltransferase; Humans; Male; Middle Aged | 2006 |
Detection of acetaminophen protein adducts in children with acute liver failure of indeterminate cause.
Topics: Acetaminophen; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Blood Proteins; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cysteine; Female; Humans; Infant; Infant, Newborn; Liver; Liver Failure, Acute; Male; Protein Binding; Sensitivity and Specificity | 2006 |
Simultaneous modelling of the Michaelis-Menten kinetics of paracetamol sulphation and glucuronidation.
Topics: Acetaminophen; Adult; Chromatography, High Pressure Liquid; Cross-Over Studies; Cysteine; Dose-Response Relationship, Drug; Female; Humans; Male; Molecular Structure; Pain; Time; Young Adult | 2009 |
Alteration in metabolism and toxicity of acetaminophen upon repeated administration in rats.
Topics: Acetaminophen; Alanine Transaminase; Aminopyrine; Analgesics, Non-Narcotic; Animals; Anisoles; Aspartate Aminotransferases; Cysteine; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Injections, Intraperitoneal; L-Iditol 2-Dehydrogenase; Liver; Microsomes, Liver; Nitrophenols; Rats; Rats, Sprague-Dawley | 2009 |
Detection of acetaminophen-cysteine adducts in cases of indeterminate liver failure is not diagnostic of intentional overdose.
Topics: Acetaminophen; Chemical and Drug Induced Liver Injury; Cysteine; Drug Overdose; Humans; Liver Failure, Acute | 2011 |
Protection against acetaminophen-induced liver injury by allopurinol is dependent on aldehyde oxidase-mediated liver preconditioning.
Topics: Acetaminophen; Aldehyde Oxidase; Allopurinol; Animals; Chemical and Drug Induced Liver Injury; Cysteine; Drug Overdose; Glutathione; JNK Mitogen-Activated Protein Kinases; Liver; Male; Metallothionein; Mice; Mice, Inbred C3H; Mitochondria; Oxypurinol; Phosphorylation; Xanthine Oxidase | 2014 |
Prolonged Acetaminophen-Protein Adduct Elimination During Renal Failure, Lack of Adduct Removal by Hemodiafiltration, and Urinary Adduct Concentrations After Acetaminophen Overdose.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver Injury; Cohort Studies; Cysteine; Drug Overdose; Female; Half-Life; Hemodiafiltration; Humans; Male; Prospective Studies; Proteins; Renal Circulation; Renal Insufficiency; Tandem Mass Spectrometry | 2015 |
Confirming the Causative Role of Acetaminophen in Indeterminate Acute Liver Failure Using Acetaminophen-Cysteine Adducts.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Biomarkers; Centrifugation; Cysteine; Dialysis; Drug Overdose; Female; Humans; Liver Failure, Acute; Liver Function Tests | 2015 |
Protein-Derived Acetaminophen-Cysteine Can Be Detected After Repeated Supratherapeutic Ingestion of Acetaminophen in the Absence of Hepatotoxicity.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Biomarkers; Chemical and Drug Induced Liver Injury; Cysteine; Drug Administration Schedule; Female; Humans; Interviews as Topic; Liver Function Tests; Male; Middle Aged; Pain; Pain Clinics; Protein Binding; Risk Factors; Surveys and Questionnaires; Time Factors; Transaminases; Treatment Outcome | 2015 |
Morbidly Obese Patients Exhibit Increased CYP2E1-Mediated Oxidation of Acetaminophen.
Topics: Acetaminophen; Adolescent; Adult; Area Under Curve; Body Mass Index; Cysteine; Cytochrome P-450 CYP2E1; Female; Humans; Male; Middle Aged; Models, Biological; Obesity, Morbid; Prospective Studies; Young Adult | 2016 |
Microsomal prostaglandin E synthase 2 deficiency is resistant to acetaminophen-induced liver injury.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Cysteine; Dinoprostone; Glutathione; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Mice, Knockout; Prostaglandin-E Synthases | 2019 |
A hepatoprotection study of Radix Bupleuri on acetaminophen-induced liver injury based on CYP450 inhibition.
Topics: Acetaminophen; Animals; Bupleurum; Chemical and Drug Induced Liver Injury; Cysteine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Disease Models, Animal; Liver; Male; Mice, Inbred ICR; Phytotherapy; Plant Extracts; Rats, Wistar | 2019 |
Detection of Distinct Distributions of Acetaminophen and Acetaminophen-Cysteine in Kidneys up to 10 μm Resolution and Identification of a Novel Acetaminophen Metabolite Using an AP-MALDI Imaging Mass Microscope.
Topics: Acetaminophen; Cysteine; Kidney; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2023 |