Compounds > acetaminophen

acetaminophen and 4-hydroxy-2-nonenal

acetaminophen has been researched along with 4-hydroxy-2-nonenal in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's6 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carpenter, AB; Kiningham, KK; Sullivan, SB; Terneus, MV; Valentovic, MA1
Brown, JM; Carpenter, AB; Terneus, MV; Valentovic, MA1
Jiang, YZ; Lian, LH; Nan, JX; Wang, AY; Wu, YL1
Arulselvan, P; Fakurazi, S; Sharifudin, SA1
Choi, J; Jang, SI; Kim, SZ; Park, KH; Shin, JH1
Ball, JG; Brown, JM; Kuhlman, C; Labenski, MT; Lamyaithong, AB; Lau, SS; Terneus, MV; Valentovic, MA1
Chen, C; Fu, CL; Hu, JN; Jiang, S; Leng, J; Li, W; Ren, S; Wang, YP; Wang, Z; Zhang, J1
Chen, C; Hu, JN; Leng, J; Li, W; Liu, Z; Ren, S; Wang, Z; Xu, XY1

Other Studies

8 other study(ies) available for acetaminophen and 4-hydroxy-2-nonenal

ArticleYear
Comparison of S-Adenosyl-L-methionine and N-acetylcysteine protective effects on acetaminophen hepatic toxicity.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 320, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Aldehydes; Animals; Antidotes; Blotting, Western; Glutathione; Liver; Male; Mice; Mice, Inbred C57BL; Organ Size; Protein Carbonylation; S-Adenosylmethionine

2007
Comparison of S-adenosyl-L-methionine (SAMe) and N-acetylcysteine (NAC) protective effects on hepatic damage when administered after acetaminophen overdose.
    Toxicology, 2008, Feb-03, Volume: 244, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Aldehydes; Analysis of Variance; Animals; Blotting, Western; Drug Overdose; Glutathione; Injections, Intraperitoneal; Lipid Peroxidation; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL; Microscopy, Polarization; Organ Size; Protein Carbonylation; S-Adenosylmethionine; Time Factors

2008
Gentiana manshurica Kitagawa prevents acetaminophen-induced acute hepatic injury in mice via inhibiting JNK/ERK MAPK pathway.
    World journal of gastroenterology, 2010, Jan-21, Volume: 16, Issue:3

    Topics: Acetaminophen; Alanine Transaminase; Aldehydes; Animals; Apoptosis; Aspartate Aminotransferases; Caspase 3; Caspase Inhibitors; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drugs, Chinese Herbal; Extracellular Signal-Regulated MAP Kinases; Gentiana; Glutathione; Glutathione Peroxidase; Male; Malondialdehyde; MAP Kinase Kinase 4; Mice; Mice, Inbred Strains; Signal Transduction

2010
Moringa oleifera hydroethanolic extracts effectively alleviate acetaminophen-induced hepatotoxicity in experimental rats through their antioxidant nature.
    Molecules (Basel, Switzerland), 2012, Jul-10, Volume: 17, Issue:7

    Topics: Acetaminophen; Aldehydes; Animals; Antioxidants; Biomarkers; Biphenyl Compounds; Ethanol; Flowers; Fluorescence Recovery After Photobleaching; Free Radical Scavengers; Glutathione; Liver; Liver Diseases; Liver Function Tests; Male; Malondialdehyde; Moringa oleifera; Oxidative Stress; Phenols; Phytotherapy; Picrates; Plant Extracts; Rats; Rats, Sprague-Dawley; Water

2012
The ameliorative effects of L-2-oxothiazolidine-4-carboxylate on acetaminophen-induced hepatotoxicity in mice.
    Molecules (Basel, Switzerland), 2013, Mar-18, Volume: 18, Issue:3

    Topics: Acetaminophen; Alanine Transaminase; Aldehydes; Analgesics, Non-Narcotic; Animals; Antioxidants; Apoptosis; Aspartate Aminotransferases; Caspase 3; Chemical and Drug Induced Liver Injury; DNA Fragmentation; Glutathione; Glutathione Peroxidase; Liver; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Necrosis; Oxidative Stress; Pyrrolidonecarboxylic Acid; Thiazolidines; Tyrosine

2013
S-adenosyl-l-methionine protection of acetaminophen mediated oxidative stress and identification of hepatic 4-hydroxynonenal protein adducts by mass spectrometry.
    Toxicology and applied pharmacology, 2014, Dec-01, Volume: 281, Issue:2

    Topics: Acetaminophen; Aldehydes; Animals; Antioxidants; Carbamoyl-Phosphate Synthase (Ammonia); Chemical and Drug Induced Liver Injury; Chromatography, Liquid; Cytoprotection; Disease Models, Animal; Liver; Male; Mice, Inbred BALB C; Mitochondria, Liver; Oxidative Stress; Protein Carbonylation; Protein Processing, Post-Translational; S-Adenosylmethionine; Sarcosine Dehydrogenase; Tandem Mass Spectrometry

2014
NF-κB and AMPK/PI3K/Akt signaling pathways are involved in the protective effects of Platycodon grandiflorum saponins against acetaminophen-induced acute hepatotoxicity in mice.
    Phytotherapy research : PTR, 2018, Volume: 32, Issue:11

    Topics: Acetaminophen; Aldehydes; AMP-Activated Protein Kinases; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Glutathione; Interleukin-1beta; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; NF-kappa B; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphorylation; Plant Roots; Platycodon; Proto-Oncogene Proteins c-akt; Saponins; Signal Transduction; Tumor Necrosis Factor-alpha

2018
Improved protective effects of American ginseng berry against acetaminophen-induced liver toxicity through TNF-α-mediated caspase-3/-8/-9 signaling pathways.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2018, Dec-01, Volume: 51

    Topics: Acetaminophen; Alanine Transaminase; Aldehydes; Animals; Aspartate Aminotransferases; Caspases; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Fruit; Glutathione; Interleukin-1beta; Liver; Male; Malondialdehyde; Mice; Necrosis; Oxidative Stress; Panax; Plant Extracts; Signal Transduction; Superoxide Dismutase; Transcription Factor RelA; Tumor Necrosis Factor-alpha

2018