Compounds > acetaminophen

acetaminophen and 4-aminophenol

acetaminophen has been researched along with 4-aminophenol in 84 studies

Research

Studies (84)

TimeframeStudies, this research(%)All Research%
pre-199015 (17.86)18.7374
1990's12 (14.29)18.2507
2000's17 (20.24)29.6817
2010's26 (30.95)24.3611
2020's14 (16.67)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Hilvo, M; Innocenti, A; Parkkila, S; Scozzafava, A; Supuran, CT1
Innocenti, A; Scozzafava, A; Supuran, CT; Vullo, D1
Ekins, S; Williams, AJ; Xu, JJ1
Bua, S; Capasso, C; Del Prete, S; Entezari Heravi, Y; Gratteri, P; Nocentini, A; Saboury, AA; Sereshti, H; Supuran, CT1
Å Nilsson, JL; Blomgren, A; Blomqvist, A; Boudieu, L; Eschalier, A; Grundemar, L; Mallet, C; Nilsson, UJ; Shionoya, K; Sundin, AP; Zygmunt, PM1
Foster, JR; Fowler, LM; Lock, EA; Moore, RB1
Milch, G; Szabó, E1
Atta, NF; Galal, A; Karagözler, AE; Mark, HB; Russell, GC; Zimmer, H1
Eyanagi, R; Hisanari, Y; Shigematsu, H1
Bartolone, JB; Beierschmitt, WP; Cohen, SD; Emeigh Hart, SG; Khairallah, EA; Wyand, DS1
Bramwell, H; Cass, AE; Gibbs, PN; Green, MJ1
Rustum, AM1
Jain, A; Verma, KK1
Clark, JD; Clark, PM; Wheatley, T1
Bernstein, J; DeShone, GM; Hoefle, D; Hook, JB; Kuo, CH; Newton, JF1
Atkinson, T; Campbell, RS; Hammond, PM; Price, CP; Scawen, MD1
Baumann, J; von Bruchlausen, F1
Bernstein, J; Hook, JB; Newton, JF; Rush, GF; Yoshimoto, M1
Gemborys, MW; Hook, JB; Kuo, CH; Mudge, GH; Newton, JF1
Carpenter, HM; Mudge, GH1
Caddick, S; Farrant, RD; Lindon, JC; Nicholls, AW; Nicholson, JK; Wilson, ID1
Holme, JA; Hongslo, JK; Rannug, U; Srám, R1
Chang, MJ; Kao, GI; Tsai, CT1
Brennan, RJ; Schiestl, RH1
Chen, TS; Song, H1
Ampurdanés, C; Bujons, J; Ladona, MG; Messeguer, A; Morató, A1
Ahmed, S; Hameed, A; Javed, MA; Tanvir, S1
Andersson, FO; Forshed, J; Jacobsson, SP1
Su, WT; Tang, X; Wu, XH; Zhang, LQ; Zhu, XL1
BOREUS, LO; SANDBERG, F2
BAADER, H; GIRGIS, S; KIESE, M; MENZEL, H; SKROBOT, L1
BONACINA, F; D ALO, F; MASSERINI, A; OSVALDO, A1
Goodin, MG; Rosengren, RJ; Walker, RJ1
Faroongsarng, D; Kadejinda, W; Sunthornpit, A1
Fang, Y; Liu, C; Yu, Y; Zhou, B1
Galera, R; Martínez-Lozano, C; Pérez-Ruiz, T; Tomás, V1
Apak, R; Cekiç, SD; Filik, H; Kiliç, E; Sener, I1
Almeida, VK; Eldridge, SL; Korir, AK; Larive, CK1
Chu, Q; Jiang, L; Tian, X; Ye, J1
Bloomfield, MS; Dejaegher, B; Smeyers-Verbeke, J; Vander Heyden, Y1
Gao, H; Huang, Y; Liu, H; Qu, L; Xiang, B1
AXELROD, J; BRODIE, BB1
BRODIE, BB; FLINN, FB1
Cribb, AE; Grant, DM; McConkey, SE1
Hemmateenejad, B; Yousefinejad, S1
Ding, K; Lin, Z; Lu, L; Tang, F; Wu, X; Wu, Y; Zheng, M1
DeSilva, M; Gu, TT; Qiang, M; Schultz, S; Whang, K1
Admassie, S; Hunde, T; Mehretie, S; Solomon, T; Tessema, M1
Bang, WG; Choi, IG; Kim, KH; Ko, HJ1
Gobbi, AL; Kubota, LT; Santhiago, M; Shiroma, LY1
Chen, J; Hu, J; Zhang, L; Zhou, Q; Zhu, R1
Al-Shwaiyat, MK; Andruch, V; Bazel, YR; Petrushina, GA; Sklenářová, H; Solich, P; Tsiganok, LP; Vishnikin, AB1
Abdelaleem, EA; Abdelwahab, NS1
Chen, JM; Hu, J; Liu, Y; Zhang, LL1
Brabcová, I; Chocholouš, P; Maroušková, A; Šatínský, D; Solich, P1
Araújo, AN; Delerue-Matos, C; Montenegro, MC; Paíga, P; Pena, A; Santos, LH1
Chavez, PF; De Bleye, C; Dumont, E; Hubert, P; Netchacovitch, L; Piel, G; Rozet, E; Sacré, PY; Ziemons, E1
Chavez, PF; De Bleye, C; Dumont, E; Hubert, P; Lebrun, P; Netchacovitch, L; Piel, G; Sacré, PY; Ziemons, E1
Dadfarnia, S; Haji Shabani, AM; Hormozi-Nezhad, MR; Khodaveisi, J; Rohani Moghadam, M1
Kunov-Kruse, AJ; Myerson, AS; Rogers, RD; Weber, CC1
Abdelaleem, EA; Ali, NW; Hassan, ES; Naguib, IA1
Li, CN; Shen, ZF; Sun, SJ1
Mohamed, HM; Yehia, AM1
Bandyopadhyay, R; Biswas, S; Chakraborty, D; Das, R; Pramanik, P1
Hegazy, MA; Lotfy, HM; Mohamed, EH; Mowaka, S1
Achterbergh, R; Lammers, LA; Mathôt, RA; Pistorius, MC; Romijn, JA1
Buck Louis, GM; Chen, Z; Kannan, K; Kim, S; Smarr, MM1
Li, S; Qu, J; Wang, H; Zhang, S1
Boltia, SA; Elzanfaly, ES; Soudi, AT; Zaazaa, HE2
Abdelhamid, NS1
Dou, N; Qu, J1
Hamdy, AM; Ibrahim, H; Merey, HA; Saad, AS1
Bo, X; Guo, L; Niu, X1
Feng, Y; Li, Y; Tong, Y; Yang, Q; Ye, BC; Yu, S1
Abdelhamid, NS; Anwar, BH; Farid, NF; Magdy, MA; Naguib, IA1
Alatawi, H; Albalawi, I; Hogan, A; Moore, E; O'Sullivan-Carroll, E; Wang, Y1
Belova, L; Covaci, A; Fernández, SF; Jeong, Y; Kim, DH; Poma, G; Remy, S; Roggeman, M; Schoeters, G; van Nuijs, ALN; Verheyen, VJ1
Kinoshita, H; Kurogi, K; Liu, MC; Morita, C; Ono, M; Sakakibara, Y; Suiko, M; Tokunaga, Y; Ueda, Y; Yasuda, S1
Marukawa, M; Shinkawa, N; Wada, K; Yukawa, N1
Capek, J; Cesla, P; Handl, J; Kubat, M; Malinak, D; Musilek, K; Nyvltova, P; Rousar, T; Rousarova, E; Smid, L; Vanova, J1

Reviews

2 review(s) available for acetaminophen and 4-aminophenol

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
International Commission for Protection against Environmental Mutagens and Carcinogens. An evaluation of the genetic toxicity of paracetamol.
    Mutation research, 1995, Volume: 327, Issue:1-2

    Topics: Acetaminophen; Acetates; Acetic Acid; Adult; Aminophenols; Animals; Bacteria; Benzoquinones; Biotransformation; Cell Line; Child; Chromosomes; DNA Damage; DNA Repair; DNA Replication; Female; Humans; Imines; Mutagenicity Tests; Plants; Rats; Rats, Sprague-Dawley; Ribonucleotide Reductases; Rodentia

1995

Other Studies

82 other study(ies) available for acetaminophen and 4-aminophenol

ArticleYear
Carbonic anhydrase inhibitors: Inhibition of the new membrane-associated isoform XV with phenols.
    Bioorganic & medicinal chemistry letters, 2008, Jun-15, Volume: 18, Issue:12

    Topics: Animals; Binding Sites; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Dose-Response Relationship, Drug; Humans; Hydrogen Bonding; Isoenzymes; Mice; Molecular Structure; Phenols; Stereoisomerism; Structure-Activity Relationship

2008
Carbonic anhydrase inhibitors: inhibition of mammalian isoforms I-XIV with a series of substituted phenols including paracetamol and salicylic acid.
    Bioorganic & medicinal chemistry, 2008, Aug-01, Volume: 16, Issue:15

    Topics: Acetaminophen; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Molecular Structure; Protein Isoforms; Salicylic Acid; Structure-Activity Relationship

2008
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Inhibition of Malassezia globosa carbonic anhydrase with phenols.
    Bioorganic & medicinal chemistry, 2017, 05-01, Volume: 25, Issue:9

    Topics: Acetazolamide; Carbonic Anhydrase I; Carbonic Anhydrase Inhibitors; Dandruff; Humans; Hydrogen Bonding; Malassezia; Molecular Docking Simulation; Phenols; Structure-Activity Relationship

2017
Paracetamol analogues conjugated by FAAH induce TRPV1-mediated antinociception without causing acute liver toxicity.
    European journal of medicinal chemistry, 2021, Mar-05, Volume: 213

    Topics: Acetaminophen; Amidohydrolases; Aminophenols; Analgesics; Animals; Antipyretics; Arachidonic Acids; Brain; Female; Humans; Indazoles; Liver; Male; Mice, Inbred C57BL; Models, Molecular; Pain; Pain Measurement; Prostaglandin-Endoperoxide Synthases; Rats, Wistar; Structure-Activity Relationship; Transient Receptor Potential Channels; TRPV Cation Channels

2021
Nephrotoxicity of 4-aminophenol glutathione conjugate.
    Human & experimental toxicology, 1991, Volume: 10, Issue:6

    Topics: Acetaminophen; Aminophenols; Animals; Glutathione; Kidney; Kidney Diseases; Liver; Male; Rats; Rats, Inbred F344

1991
Derivative spectrophotometric assay of acetaminophen and spectrofluorimetric determination of its main impurity.
    Journal of pharmaceutical and biomedical analysis, 1991, Volume: 9, Issue:10-12

    Topics: Acetaminophen; Aminophenols; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet

1991
Electrochemistry and detection of some organic and biological molecules at conducting poly(3-methylthiophene) electrodes.
    Biosensors & bioelectronics, 1991, Volume: 6, Issue:4

    Topics: Acetaminophen; Aminophenols; Ascorbic Acid; Biosensing Techniques; Catechols; Dopamine; Electrochemistry; Epinephrine; Hydroquinones; Iron; NAD; Polymers; Thiophenes

1991
Studies of paracetamol/phenacetin toxicity: isolation and characterization of p-aminophenol-glutathione conjugate.
    Xenobiotica; the fate of foreign compounds in biological systems, 1991, Volume: 21, Issue:6

    Topics: Acetaminophen; Aminophenols; Animals; Biotransformation; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Glutathione; Horseradish Peroxidase; Kidney; Magnetic Resonance Spectroscopy; Male; Microsomes; Microsomes, Liver; Oxidation-Reduction; Phenacetin; Rats; Rats, Inbred Strains

1991
Evidence against deacetylation and for cytochrome P450-mediated activation in acetaminophen-induced nephrotoxicity in the CD-1 mouse.
    Toxicology and applied pharmacology, 1991, Volume: 107, Issue:1

    Topics: Acetaminophen; Acetylation; Aminophenols; Animals; Blood Urea Nitrogen; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Kidney Diseases; Kidney Tubular Necrosis, Acute; Kidney Tubules, Proximal; Male; Mice; Nitrophenols; Piperonyl Butoxide; Proteins; Tritolyl Phosphates

1991
[Antipyretic analgesics derived from para-aminophenol].
    Practica odontologica, 1990, Volume: 11, Issue:11

    Topics: Acetaminophen; Aminophenols; Chemical and Drug Induced Liver Injury; Kidney; Phenacetin

1990
Method for determining paracetamol in whole blood by chronoamperometry following enzymatic hydrolysis.
    The Analyst, 1990, Volume: 115, Issue:2

    Topics: Acetaminophen; Amidohydrolases; Aminophenols; Electrochemistry; Electrodes; Humans

1990
Determination of acetaminophen in human plasma by ion-pair reversed-phase high-performance liquid chromatography. Application to a single-dose pharmacokinetic study.
    Journal of chromatographic science, 1989, Volume: 27, Issue:1

    Topics: Acetaminophen; Aminophenols; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Humans; Spectrophotometry, Ultraviolet

1989
Spectrophotometric determination of aspirin by transacetylation of 4-aminophenol.
    Analytical chemistry, 1986, Volume: 58, Issue:4

    Topics: Acetaminophen; Acetylation; Aminophenols; Aspirin; Indicators and Reagents; Photometry; Spectrophotometry

1986
Urine discoloration after acetaminophen overdose.
    Clinical chemistry, 1986, Volume: 32, Issue:9

    Topics: Acetaminophen; Acute Kidney Injury; Adult; Aminophenols; Chemical and Drug Induced Liver Injury; Chromatography, Thin Layer; Colorimetry; Humans; Male; Middle Aged; Pigments, Biological; Time Factors

1986
The role of p-aminophenol in acetaminophen-induced nephrotoxicity: effect of bis(p-nitrophenyl) phosphate on acetaminophen and p-aminophenol nephrotoxicity and metabolism in Fischer 344 rats.
    Toxicology and applied pharmacology, 1985, Volume: 81, Issue:3 Pt 1

    Topics: Acetaminophen; Aminophenols; Animals; Body Weight; Injections, Intraperitoneal; Kidney Cortex Necrosis; Male; Nitrophenols; Organ Size; Rats; Rats, Inbred F344

1985
Development of an enzyme-based assay for acetaminophen.
    Analytical biochemistry, 1984, Nov-15, Volume: 143, Issue:1

    Topics: Acetaminophen; Amidohydrolases; Aminophenols; Chemical Phenomena; Chemistry; Colorimetry; Humans; Hydrolysis; Indicators and Reagents; Spectrophotometry; Tablets

1984
Inhibitory actions of desacetylation products of phenacetin and paracetamol on prostaglandin synthetases in neuronal and glial cell lines and rat renal medulla.
    Life sciences, 1982, May-24, Volume: 30, Issue:21

    Topics: Acetaminophen; Aminophenols; Animals; Astrocytoma; Cell Line; Cyclooxygenase Inhibitors; In Vitro Techniques; Kidney Medulla; Male; Mice; Neoplasms, Experimental; Neuroblastoma; Phenacetin; Phenetidine; Rats; Rats, Inbred Strains

1982
Acetaminophen nephrotoxicity in the rat. II. Strain differences in nephrotoxicity and metabolism of p-aminophenol, a metabolite of acetaminophen.
    Toxicology and applied pharmacology, 1983, Jun-30, Volume: 69, Issue:2

    Topics: Acetaminophen; Aminophenols; Animals; Drug Resistance; In Vitro Techniques; Kidney Cortex; Kidney Diseases; Kinetics; Liver; Male; Protein Binding; Rats; Rats, Inbred F344; Rats, Inbred Strains; Species Specificity; Sulfhydryl Compounds

1983
Nephrotoxicity of p-aminophenol, a metabolite of acetaminophen, in the fischer 344 rat.
    Toxicology and applied pharmacology, 1982, Sep-15, Volume: 65, Issue:2

    Topics: Acetaminophen; Alanine Transaminase; Aminophenols; Animals; Blood Urea Nitrogen; Isomerism; Kidney Diseases; Liver; Male; Mixed Function Oxygenases; Rabbits; Rats; Rats, Inbred F344

1982
Acetaminophen nephrotoxicity: studies on renal acetylation and deacetylation.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 218, Issue:1

    Topics: Acetaminophen; Acetylation; Acetyltransferases; Aminophenols; Animals; In Vitro Techniques; Kidney; Kidney Diseases; Male; Mice; p-Aminohippuric Acid

1981
High resolution NMR spectroscopic studies on the metabolism and futile deacetylation of 4-hydroxyacetanilide (paracetamol) in the rat.
    Biochemical pharmacology, 1995, Apr-18, Volume: 49, Issue:8

    Topics: Acetaminophen; Acetylation; Aminophenols; Animals; Carbon Radioisotopes; Deuterium; Magnetic Resonance Spectroscopy; Models, Chemical; Rats

1995
Biological monitoring of exposure to low dose aniline, p-aminophenol, and acetaminophen.
    Bulletin of environmental contamination and toxicology, 1993, Volume: 51, Issue:4

    Topics: Acetaminophen; Aminophenols; Aniline Compounds; Animals; Colorimetry; Environmental Monitoring; Female; Humans; Rats; Rats, Wistar

1993
Aniline and its metabolites generate free radicals in yeast.
    Mutagenesis, 1997, Volume: 12, Issue:4

    Topics: Acetaminophen; Aminophenols; Aniline Compounds; Bacterial Proteins; beta-Galactosidase; Carcinogens; Dose-Response Relationship, Drug; Escherichia coli; Escherichia coli Proteins; Ethyl Methanesulfonate; Fluoresceins; Free Radicals; Recombination, Genetic; Saccharomyces cerevisiae; Sequence Deletion; Superoxide Dismutase; Trans-Activators; Transcription Factors

1997
p-Aminophenol-induced liver toxicity: tentative evidence of a role for acetaminophen.
    Journal of biochemical and molecular toxicology, 2001, Volume: 15, Issue:1

    Topics: Acetaminophen; Acetylation; Alanine Transaminase; Aminophenols; Animals; Ascorbic Acid; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Cysteine; Cystine; Dose-Response Relationship, Drug; Drug Synergism; Glutathione; Glutathione Disulfide; L-Iditol 2-Dehydrogenase; Liver; Male; Mice; Mice, Inbred C57BL

2001
Metabolism of (R)- and (S)-3-(phenylamino)propane-1,2-diol in C57BL/6- and A/J-strain mice. Identification of new metabolites with potential toxicological significance to the toxic oil syndrome.
    Chemical research in toxicology, 2001, Volume: 14, Issue:8

    Topics: Acetaminophen; Aminophenols; Aniline Compounds; Animals; Chromatography, High Pressure Liquid; Fatty Acids, Monounsaturated; Food Contamination; Mice; Mice, Inbred C57BL; Plant Oils; Propylene Glycols; Rapeseed Oil

2001
Isolation and characterization of a pseudomonas strain that degrades 4-acetamidophenol and 4-aminophenol.
    Biodegradation, 2001, Volume: 12, Issue:5

    Topics: Acetaminophen; Aminophenols; Biodegradation, Environmental; Chromatography, High Pressure Liquid; Culture Media; Drug Industry; Industrial Waste; Pakistan; Pseudomonas; Spectrophotometry, Ultraviolet; Waste Disposal, Fluid

2001
NMR and Bayesian regularized neural network regression for impurity determination of 4-aminophenol.
    Journal of pharmaceutical and biomedical analysis, 2002, Jul-01, Volume: 29, Issue:3

    Topics: Acetaminophen; Aminophenols; Bayes Theorem; Calibration; Drug Contamination; Nuclear Magnetic Resonance, Biomolecular

2002
[Research into simultaneous spectrophotometric determination of components in cough syrup by principal component regression method].
    Guang pu xue yu guang pu fen xi = Guang pu, 2002, Volume: 22, Issue:3

    Topics: Acetaminophen; Aminophenols; Analgesics, Non-Narcotic; Caffeine; Chlorpheniramine; Drug Combinations; Expectorants; Guaifenesin; Histamine H1 Antagonists; Sensitivity and Specificity; Spectrophotometry, Ultraviolet

2002
A comparison of some pharmacological effects of acetophenetidin and N-acetyl p-aminophenol.
    Acta physiologica Scandinavica, 1953, Volume: 28, Issue:2-3

    Topics: Acetaminophen; Aminophenols; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Phenacetin; Phenols

1953
The analgesic action of n-acetyl p-aminophenol and its combination with some other substances.
    Acta physiologica Scandinavica, 1953, Volume: 28, Issue:2-3

    Topics: Acetaminophen; Aminophenols; Analgesics; Humans; Phenols

1953
[The influence of age on the conversion of phenacetin, p-phenetidin, N-acetyl-p-aminophenol, p-aminophenol and aniline in the dog].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1960, Volume: 241

    Topics: Acetaminophen; Acetanilides; Aging; Aminophenols; Aniline Compounds; Animals; Dogs; Humans; Phenacetin

1960
[DERIVATIVES OF P-AMINOPHENOL WITH ANTIPYRETIC AND ANALGESIC ACTIVITY].
    Il Farmaco; edizione scientifica, 1964, Volume: 19

    Topics: Acetaminophen; Aminophenols; Analgesics; Analgesics, Non-Narcotic; Anilides; Antipyretics; Chemistry, Pharmaceutical; Pharmacology; Phenols; Rats; Research

1964
Renal PGE2 production in the human and rat following phenacetin, acetaminophen and p-aminophenol.
    Research communications in molecular pathology and pharmacology, 2002, Volume: 111, Issue:1-4

    Topics: Acetaminophen; Aminophenols; Animals; Dinoprostone; Humans; Immunoassay; Kidney Medulla; Male; Microsomes; Phenacetin; Rats; Rats, Sprague-Dawley

2002
Thermal behavior of a pharmaceutical solid acetaminophen doped with p-aminophenol.
    AAPS PharmSciTech, 2000, Jul-30, Volume: 1, Issue:3

    Topics: Acetaminophen; Aminophenols; Calorimetry, Differential Scanning; Hot Temperature; Pharmaceutical Preparations; Phase Transition; Solubility; Solutions; Thermodynamics

2000
[Research into determination of tricomponent sample by ridge regression spectrophotometry].
    Guang pu xue yu guang pu fen xi = Guang pu, 1999, Volume: 19, Issue:2

    Topics: Acetaminophen; Aminophenols; Analgesics, Non-Narcotic; Nitrophenols; Spectrophotometry

1999
Migration behaviour and separation of acetaminophen and p-aminophenol in capillary zone electrophoresis: analysis of drugs based on acetaminophen.
    Journal of pharmaceutical and biomedical analysis, 2005, Jun-01, Volume: 38, Issue:1

    Topics: Acetaminophen; Aminophenols; Buffers; Calibration; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Osmolar Concentration

2005
Spectrophotometric determination of paracetamol in urine with tetrahydroxycalix[4]arene as a coupling reagent and preconcentration with triton X-114 using cloud point extraction.
    Chemical & pharmaceutical bulletin, 2006, Volume: 54, Issue:6

    Topics: Acetaminophen; Aminophenols; Drugs, Chinese Herbal; Indicators and Reagents; Octoxynol; Polyethylene Glycols; Spectrophotometry; Surface-Active Agents; Temperature

2006
Separation and analysis of trace degradants in a pharmaceutical formulation using on-line capillary isotachophoresis-NMR.
    Analytical chemistry, 2007, Nov-15, Volume: 79, Issue:22

    Topics: Acetaminophen; Aminophenols; Chemistry, Pharmaceutical; Chromatography, Liquid; Electrophoresis, Capillary; Magnetic Resonance Spectroscopy; Molecular Structure; Online Systems; Tandem Mass Spectrometry; Water

2007
Rapid determination of acetaminophen and p-aminophenol in pharmaceutical formulations using miniaturized capillary electrophoresis with amperometric detection.
    Analytica chimica acta, 2008, Jan-14, Volume: 606, Issue:2

    Topics: Acetaminophen; Aminophenols; Analgesics, Non-Narcotic; Electrochemistry; Electrophoresis, Capillary; Miniaturization; Molecular Structure; Mutagens; Pharmaceutical Preparations; Reproducibility of Results; Time Factors

2008
Validation of a fluorimetric assay for 4-aminophenol in paracetamol formulations.
    Talanta, 2008, Mar-15, Volume: 75, Issue:1

    Topics: Acetaminophen; Aminophenols; Color; Fluorometry; Pharmaceutical Preparations; Powders; Reproducibility of Results; Sensitivity and Specificity; Tablets

2008
Structure analysis of aromatic medicines containing nitrogen using near-infrared spectroscopy and generalized two-dimensional correlation spectroscopy.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2008, Dec-15, Volume: 71, Issue:4

    Topics: Acetaminophen; Amides; Aminophenols; Hydrogen Bonding; Models, Chemical; Molecular Structure; Niacin; Niacinamide; Nitrogen; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Spectroscopy, Near-Infrared; Temperature

2008
The estimation of acetanilide and its metabolic products, aniline, N-acetyl p-aminophenol and p-amino-phenol, free and total conjugated, in biological fluids and tissues.
    The Journal of pharmacology and experimental therapeutics, 1948, Volume: 94, Issue:1

    Topics: Acetaminophen; Acetanilides; Aminophenols; Aniline Compounds; Humans; Phenol; Phenols

1948
The effect on the pain threshold of N-acetyl p-aminophenol, a product derived in the body from acetanilide.
    The Journal of pharmacology and experimental therapeutics, 1948, Volume: 94, Issue:1

    Topics: Acetaminophen; Acetanilides; Aminophenols; Humans; Pain Threshold

1948
The role of para-aminophenol in acetaminophen-induced methemoglobinemia in dogs and cats.
    Journal of veterinary pharmacology and therapeutics, 2009, Volume: 32, Issue:6

    Topics: Acetaminophen; Acetyltransferases; Aminophenols; Animals; Cat Diseases; Cats; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Erythrocytes; Female; Gene Expression Regulation, Enzymologic; Male; Methemoglobinemia; Mice; Mice, Knockout; Rats; Rats, Sprague-Dawley

2009
Simultaneous spectrophotometric determination of paracetamol and para-aminophenol in pharmaceutical dosage forms using two novel multivariate standard addition methods based on net analyte signal and rank annihilation factor analysis.
    Drug testing and analysis, 2012, Volume: 4, Issue:6

    Topics: Acetaminophen; Aminophenols; Analgesics, Non-Narcotic; Factor Analysis, Statistical; Limit of Detection; Multivariate Analysis; Sensitivity and Specificity; Spectrophotometry, Ultraviolet

2012
Simultaneous analysis of acetaminophen, p-aminophenol and aspirin metabolites by hydrophilic interaction and strong anion exchange capillary liquid chromatography coupled to amperometric detection.
    Journal of separation science, 2011, Volume: 34, Issue:16-17

    Topics: Acetaminophen; Aged; Aged, 80 and over; Aminophenols; Aspirin; Chromatography, Ion Exchange; Female; Humans; Hydrophobic and Hydrophilic Interactions; Male

2011
Effects of the analgesic acetaminophen (Paracetamol) and its para-aminophenol metabolite on viability of mouse-cultured cortical neurons.
    Basic & clinical pharmacology & toxicology, 2012, Volume: 110, Issue:2

    Topics: Acetaminophen; Aminophenols; Analgesics; Animals; Brain; Cell Survival; Cells, Cultured; Mice; Mice, Inbred C57BL; Neurons; Pain; Receptor, Cannabinoid, CB1

2012
Simultaneous determination of N-acetyl-p-aminophenol and p-aminophenol with poly(3,4-ethylenedioxythiophene) modified glassy carbon electrode.
    Talanta, 2011, Sep-15, Volume: 85, Issue:3

    Topics: Acetaminophen; Aminophenols; Bridged Bicyclo Compounds, Heterocyclic; Carbon; Electrochemical Techniques; Electrodes; Glass; Humans; Hydrogen-Ion Concentration; Polymers; Reproducibility of Results

2011
Production of p-acetaminophenol by whole-cell catalysis using Escherichia coli overexpressing bacterial aryl acylamidase.
    Biotechnology letters, 2012, Volume: 34, Issue:4

    Topics: Acetaminophen; Amidohydrolases; Aminophenols; Escherichia coli; Gene Expression; Hydrogen-Ion Concentration; Sodium Acetate; Temperature

2012
Separation and electrochemical detection of paracetamol and 4-aminophenol in a paper-based microfluidic device.
    Analytica chimica acta, 2012, May-06, Volume: 725

    Topics: Acetaminophen; Aminophenols; Antipyretics; Capillary Electrochromatography; Electrochemical Techniques; Electrodes; Limit of Detection; Microfluidic Analytical Techniques; Paper

2012
Degradation of paracetamol by pure bacterial cultures and their microbial consortium.
    Applied microbiology and biotechnology, 2013, Volume: 97, Issue:8

    Topics: Acetaminophen; Aminophenols; Biotransformation; Carbon; DNA, Bacterial; DNA, Ribosomal; Hydroquinones; Metabolic Networks and Pathways; Microbial Consortia; Molecular Sequence Data; Pseudomonas; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Stenotrophomonas

2013
Highly sensitive sequential injection determination of p-aminophenol in paracetamol formulations with 18-molybdodiphosphate heteropoly anion based on elimination of Schlieren effect.
    Talanta, 2012, Jul-15, Volume: 96

    Topics: Acetaminophen; Acetates; Aminophenols; Buffers; Chemistry, Pharmaceutical; Color; Flow Injection Analysis; Indicators and Reagents; Limit of Detection; Linear Models; Molybdenum; Phosphoric Acids; Signal-To-Noise Ratio; Spectrophotometry

2012
Stability-indicating TLC-densitometric method for simultaneous determination of paracetamol and chlorzoxazone and their toxic impurities.
    Journal of chromatographic science, 2013, Volume: 51, Issue:2

    Topics: Acetaminophen; Aminophenols; Capsules; Chlorophenols; Chlorzoxazone; Chromatography, Thin Layer; Densitometry; Drug Contamination; Regression Analysis; Reproducibility of Results; Sensitivity and Specificity

2013
Degradation of paracetamol by Pseudomonas aeruginosa strain HJ1012.
    Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 2013, Volume: 48, Issue:7

    Topics: Acetaminophen; Aminophenols; Carbon Dioxide; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Hydroquinones; Kinetics; Metabolic Networks and Pathways; Microscopy, Electron, Transmission; Pseudomonas aeruginosa; Water Pollutants, Chemical; Water Purification

2013
Green chromatography separation of analytes of greatly differing properties using a polyethylene glycol stationary phase and a low-toxic water-based mobile phase.
    Analytical and bioanalytical chemistry, 2013, Volume: 405, Issue:18

    Topics: Acetaminophen; Acetonitriles; Aminophenols; Antipyrine; Caffeine; Calibration; Chromatography, High Pressure Liquid; Ethylamines; Hydrophobic and Hydrophilic Interactions; Methanol; Polyethylene Glycols; Reproducibility of Results; Tablets; Ultraviolet Rays

2013
Development of a simple analytical method for the simultaneous determination of paracetamol, paracetamol-glucuronide and p-aminophenol in river water.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2013, Jul-01, Volume: 930

    Topics: Acetaminophen; Aminophenols; Chromatography, High Pressure Liquid; Limit of Detection; Linear Models; Portugal; Reproducibility of Results; Rivers; Solid Phase Extraction; Water Pollutants, Chemical

2013
Determination of 4-aminophenol in a pharmaceutical formulation using surface enhanced Raman scattering: from development to method validation.
    Talanta, 2013, Nov-15, Volume: 116

    Topics: Acetaminophen; Aminophenols; Calibration; Drug Contamination; Metal Nanoparticles; Microscopy, Electron, Transmission; Powders; Reproducibility of Results; Silver; Spectrum Analysis, Raman; Surface Properties

2013
Development of a quantitative approach using surface-enhanced Raman chemical imaging: first step for the determination of an impurity in a pharmaceutical model.
    Journal of pharmaceutical and biomedical analysis, 2014, Volume: 90

    Topics: Acetaminophen; Aminophenols; Limit of Detection; Metal Nanoparticles; Silver; Spectrum Analysis, Raman; Sulfhydryl Compounds; Tablets

2014
Artificial neural network assisted kinetic spectrophotometric technique for simultaneous determination of paracetamol and p-aminophenol in pharmaceutical samples using localized surface plasmon resonance band of silver nanoparticles.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2015, Mar-05, Volume: 138

    Topics: Acetaminophen; Aminophenols; Calibration; Limit of Detection; Metal Nanoparticles; Microscopy, Electron, Transmission; Nanotechnology; Neural Networks, Computer; Povidone; Silver; Spectrophotometry; Spectrophotometry, Ultraviolet; Surface Plasmon Resonance; Tablets

2015
Manipulation of ionic liquid anion-solute-antisolvent interactions for the purification of acetaminophen.
    Chemical communications (Cambridge, England), 2015, Mar-11, Volume: 51, Issue:20

    Topics: Acetaminophen; Aminophenols; Crystallization; Hydrogen Bonding; Ionic Liquids; Solubility

2015
HPTLC and RP-HPLC methods for simultaneous determination of Paracetamol and Pamabrom in presence of their potential impurities.
    Journal of pharmaceutical and biomedical analysis, 2015, Oct-10, Volume: 114

    Topics: Acetaminophen; Acetic Acid; Acetonitriles; Aminophenols; Buffers; Calibration; Chloroform; Chromatography, High Pressure Liquid; Drug Combinations; Drug Contamination; Hydrogen-Ion Concentration; Light; Methanol; Phosphates; Propanolamines; Reproducibility of Results; Tablets; Tablets, Enteric-Coated; Theophylline

2015
[Determination of serum acetaminophen based on the diazo reaction and its application in the evaluation of gastric emptying].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2015, Volume: 50, Issue:5

    Topics: Acetaminophen; Aminophenols; Animals; Gastric Emptying; Mice; Mice, Inbred ICR

2015
Chemometrics resolution and quantification power evaluation: Application on pharmaceutical quaternary mixture of Paracetamol, Guaifenesin, Phenylephrine and p-aminophenol.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2016, Jan-05, Volume: 152

    Topics: Acetaminophen; Aminophenols; Analgesics, Non-Narcotic; Drug Combinations; Drug Contamination; Expectorants; Guaifenesin; Least-Squares Analysis; Multivariate Analysis; Nasal Decongestants; Neural Networks, Computer; Phenylephrine; Principal Component Analysis; Spectrophotometry

2016
A simple synthesis of nitrogen doped porous graphitic carbon: Electrochemical determination of paracetamol in presence of ascorbic acid and p-aminophenol.
    Analytica chimica acta, 2015, Aug-26, Volume: 890

    Topics: Acetaminophen; Aminophenols; Ascorbic Acid; Catalysis; Electrochemical Techniques; Electrodes; Graphite; Nitrogen; Oxidation-Reduction; Porosity; Reproducibility of Results; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman

2015
Evaluation of the efficiency of continuous wavelet transform as processing and preprocessing algorithm for resolution of overlapped signals in univariate and multivariate regression analyses; an application to ternary and quaternary mixtures.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2016, 07-05, Volume: 164

    Topics: Acetaminophen; Algorithms; Aminophenols; Analgesics; Caffeine; Central Nervous System Stimulants; Least-Squares Analysis; Multivariate Analysis; Papaverine; Spectrophotometry; Wavelet Analysis

2016
Quantitative Method for Simultaneous Analysis of Acetaminophen and 6 Metabolites.
    Therapeutic drug monitoring, 2017, Volume: 39, Issue:2

    Topics: Acetaminophen; Aminophenols; Calibration; Chromatography, High Pressure Liquid; Humans; Limit of Detection; Plasma; Reproducibility of Results; Tandem Mass Spectrometry

2017
Male urinary paracetamol and semen quality.
    Andrology, 2017, Volume: 5, Issue:6

    Topics: Acetaminophen; Adult; Aminophenols; DNA Fragmentation; Endocrine Disruptors; Humans; Male; Middle Aged; Semen Analysis; Sperm Head; Sperm Motility

2017
Electrochemical sensor based on palladium-reduced graphene oxide modified with gold nanoparticles for simultaneous determination of acetaminophen and 4-aminophenol.
    Talanta, 2018, Feb-01, Volume: 178

    Topics: Acetaminophen; Aminophenols; Electrochemistry; Electrodes; Gold; Graphite; Hydrogen-Ion Concentration; Limit of Detection; Metal Nanoparticles; Models, Molecular; Molecular Conformation; Oxidation-Reduction; Palladium

2018
Effect of Genetic Algorithm-Based Wavelength Selection as a Preprocessing Tool on Multivariate Simultaneous Determination of Paracetamol, Orphenadrine Citrate, and Caffeine in the Presence of p-Aminophenol Impurity.
    Journal of AOAC International, 2020, Jan-01, Volume: 103, Issue:1

    Topics: Acetaminophen; Algorithms; Aminophenols; Caffeine; Calibration; Least-Squares Analysis; Orphenadrine

2020
Development and Validation of Chromatographic Methods for Simultaneous Determination of Paracetamol, Orphenadrine Citrate and Caffeine in Presence of P-aminophenol; Quantification of P-aminophenol Nephrotoxic Impurity Using LC-MS/MS.
    Journal of chromatographic science, 2020, Apr-22, Volume: 58, Issue:3

    Topics: Acetaminophen; Aminophenols; Caffeine; Chromatography, High Pressure Liquid; Chromatography, Liquid; Chromatography, Reverse-Phase; Chromatography, Thin Layer; Densitometry; Drug Contamination; Excipients; Orphenadrine; Tablets; Tandem Mass Spectrometry

2020
A comparative study of two novel validated spectrophotometric techniques for resolution of four-component mixtures with severely overlapping spectra.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2020, Jun-05, Volume: 233

    Topics: Acetaminophen; Aminophenols; Diphenhydramine; Signal Processing, Computer-Assisted; Spectrophotometry, Ultraviolet

2020
Rapid synthesis of a hybrid of rGO/AuNPs/MWCNTs for sensitive sensing of 4-aminophenol and acetaminophen simultaneously.
    Analytical and bioanalytical chemistry, 2021, Volume: 413, Issue:3

    Topics: Acetaminophen; Aminophenols; Electrochemical Techniques; Electrodes; Gold; Graphite; Limit of Detection; Metal Nanoparticles; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanotubes, Carbon; Oxidation-Reduction; Powder Diffraction; Reproducibility of Results; Spectroscopy, Fourier Transform Infrared

2021
Simultaneous Determination of Paracetamol, Propyphenazone and Caffeine in Presence of Paracetamol Impurities Using Dual-Mode Gradient HPLC and TLC Densitometry Methods.
    Journal of chromatographic science, 2021, Jan-14, Volume: 59, Issue:2

    Topics: Acetaminophen; Aminophenols; Antipyrine; Caffeine; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Codeine; Densitometry; Drug Combinations; Drug Contamination; Limit of Detection; Meprobamate; Nitrophenols; Reproducibility of Results; Sensitivity and Specificity; Solvents; Tablets

2021
Ultrasensitive simultaneous voltammetric determination of 4-aminophenol and acetaminophen based on bimetallic MOF-derived nitrogen-doped carbon coated CoNi alloy.
    Analytica chimica acta, 2021, Feb-08, Volume: 1145

    Topics: Acetaminophen; Alloys; Aminophenols; Animals; Carbon; Conus Snail; Electrochemical Techniques; Electrodes; Nitrogen; Reproducibility of Results

2021
Electrochemical sensor based on N-doped carbon dots decorated with manganese oxide nanospheres for simultaneous detection of
    The Analyst, 2021, Aug-09, Volume: 146, Issue:16

    Topics: Acetaminophen; Aminophenols; Carbon; Electrochemical Techniques; Electrodes; Limit of Detection; Manganese Compounds; Nanospheres; Oxides; Reproducibility of Results

2021
Quantitative Determination of Anti-Migraine Quaternary Mixture in Presence of p-Aminophenol and 4-Chloroacetanilide.
    Journal of chromatographic science, 2022, Jul-12, Volume: 60, Issue:6

    Topics: Acetaminophen; Acetanilides; Aminophenols; Chromatography, High Pressure Liquid

2022
Fast determination of paracetamol and its hydrolytic degradation product p-aminophenol by capillary and microchip electrophoresis with contactless conductivity detection.
    Electrophoresis, 2022, Volume: 43, Issue:7-8

    Topics: Acetaminophen; Aminophenols; Electric Conductivity; Electrophoresis, Capillary; Electrophoresis, Microchip; Hydrolysis

2022
Comprehensive investigation of persistent and mobile chemicals and per- and polyfluoroalkyl substances in urine of flemish adolescents using a suspect screening approach.
    Environmental pollution (Barking, Essex : 1987), 2022, Nov-01, Volume: 312

    Topics: Acetaminophen; Adolescent; Aminophenols; Aniline Compounds; Benzophenones; Fluorocarbons; Humans; Triacetoneamine-N-Oxyl; Trifluoroacetic Acid

2022
Investigation of radical scavenging effects of acetaminophen, p-aminophenol and their O-sulfated conjugates.
    The Journal of toxicological sciences, 2022, Volume: 47, Issue:10

    Topics: Acetaminophen; Aminophenols; Antioxidants; Phenols; Sulfates; Sulfotransferases; Xenobiotics

2022
Methodological considerations of the acetaminophen Detection Kit®: Involvement of molecular oxygen (O
    Legal medicine (Tokyo, Japan), 2023, Volume: 64

    Topics: Acetaminophen; Aminophenols; Humans; Indophenol; Oxygen

2023
Cysteine conjugates of acetaminophen and p-aminophenol are potent inducers of cellular impairment in human proximal tubular kidney HK-2 cells.
    Archives of toxicology, 2023, Volume: 97, Issue:11

    Topics: Acetaminophen; Aminophenols; Cysteine; Glutathione; Humans; Kidney

2023