acetaminophen and 2-naphthol

acetaminophen has been researched along with 2-naphthol in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19905 (25.00)18.7374
1990's9 (45.00)18.2507
2000's5 (25.00)29.6817
2010's1 (5.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Duffy, EM; Jorgensen, WL1
Duffel, MW; Sharma, V1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Bock, KW; Josting, D; Winne, D1
Dawson, J; Knowles, RG; Pogson, CI4
Horikoshi, I; Komori, M; Mizuma, T; Ueno, M1
Birkett, DJ; Lillywhite, KJ; Miners, JO; Pongmarutai, M; Yoovathaworn, K1
Handa, SS; Sharma, A1
Bock, KW; Bock-Hennig, BS1
Shihabi, ZK; Wilson, EL1
Collins, MA; Gangolli, SD; Harris, RA; Herod, IA; Lake, BG; Longland, RC1
Konishi, R; Matsuda, S; Shibasaki, J; Yamada, K1
Awazu, S; Mizuma, T1
Furusawa, N; Monshouwer, M; Van Miert, AS; Villar, D1
Hasemann, P; ter Balk, M; Wätzig, H1
Finel, M; Hirvonen, J; Kaukonen, AM; Laine, L; Siissalo, S; Tolonen, A1

Reviews

1 review(s) available for acetaminophen and 2-naphthol

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000

Other Studies

19 other study(ies) available for acetaminophen and 2-naphthol

ArticleYear
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
Comparative molecular field analysis of substrates for an aryl sulfotransferase based on catalytic mechanism and protein homology modeling.
    Journal of medicinal chemistry, 2002, Dec-05, Volume: 45, Issue:25

    Topics: Animals; Catalysis; Models, Molecular; Molecular Structure; Quantitative Structure-Activity Relationship; Rats; Sequence Homology, Amino Acid; Substrate Specificity; Sulfotransferases

2002
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Glucuronidation of paracetamol, morphine and 1-naphthol in the rat intestinal loop.
    Biochemical pharmacology, 1976, Mar-01, Volume: 25, Issue:5

    Topics: Acetaminophen; Animals; Enzyme Activation; Glucuronates; Glucuronosyltransferase; Intestinal Absorption; Intestinal Mucosa; Intestines; Jejunum; Microsomes; Microsomes, Liver; Morphine; Naphthols; Perfusion; Polyethylene Glycols; Rats; Time Factors; Uridine Diphosphate N-Acetylglucosamine

1976
Measurement of glucuronidation by isolated rat liver cells using [14C]fructose.
    Biochemical pharmacology, 1992, Mar-03, Volume: 43, Issue:5

    Topics: Acetaminophen; Animals; Carbon Radioisotopes; Cells, Cultured; Chromatography, High Pressure Liquid; Fructose; Glucosyltransferases; Glucuronates; Glucuronosyltransferase; Kinetics; Liver; Male; Naphthols; Nitrophenols; Rats; Rats, Inbred Strains

1992
Sulphate conjugation enhances reversible binding of drug to human serum albumin.
    The Journal of pharmacy and pharmacology, 1991, Volume: 43, Issue:6

    Topics: Acetaminophen; Chromatography, High Pressure Liquid; Humans; Naphthols; Naproxen; Nitrophenols; Pharmaceutical Preparations; Protein Binding; Serum Albumin; Sulfates

1991
Quantitative studies of sulphate conjugation by isolated rat liver cells using [35S]sulphate.
    Biochemical pharmacology, 1991, Jun-21, Volume: 42, Issue:1

    Topics: Acetaminophen; Animals; Barium; Cells, Cultured; Chromatography, High Pressure Liquid; Glucuronates; Kinetics; Liver; Male; Naphthols; Nitrophenols; Rats; Sulfates; Sulfur Radioisotopes

1991
Determination of sulphate conjugation in isolated rat liver cells by incorporation of 35S-labelled inorganic sulphate.
    Biochemical Society transactions, 1990, Volume: 18, Issue:6

    Topics: Acetaminophen; Animals; In Vitro Techniques; Liver; Male; Naphthols; Rats; Rats, Inbred Strains; Sulfates; Sulfur Radioisotopes

1990
Determination of glucuronidation in isolated rat liver cells by incorporation of 14C from fructose.
    Biochemical Society transactions, 1990, Volume: 18, Issue:6

    Topics: Acetaminophen; Animals; Carbon Radioisotopes; Fructose; Glucuronates; In Vitro Techniques; Liver; Male; Naphthols; Nitrophenols; Rats; Rats, Inbred Strains

1990
Characterization of paracetamol UDP-glucuronosyltransferase activity in human liver microsomes.
    Biochemical pharmacology, 1990, Aug-01, Volume: 40, Issue:3

    Topics: Acetaminophen; Cetomacrogol; Chromatography, High Pressure Liquid; Digitoxigenin; Enzyme Activation; Glucuronates; Glucuronosyltransferase; Humans; Isoenzymes; Kinetics; Microsomes, Liver; Naphthols; Substrate Specificity

1990
Hepatoprotective activity of andrographolide against galactosamine & paracetamol intoxication in rats.
    The Indian journal of medical research, 1990, Volume: 92

    Topics: Acetaminophen; Animals; Disease Models, Animal; Diterpenes; Female; Galactosamine; Hepatitis, Animal; Liver; Liver Function Tests; Male; Naphthols; Plant Extracts; Rats

1990
Differential induction of human liver UDP-glucuronosyltransferase activities by phenobarbital-type inducers.
    Biochemical pharmacology, 1987, Dec-01, Volume: 36, Issue:23

    Topics: Acetaminophen; Adolescent; Adult; Benzopyrenes; Bilirubin; Carcinoma, Hepatocellular; Enzyme Induction; Female; Glucuronosyltransferase; Humans; Hydroquinones; Hymecromone; Isoenzymes; Liver Neoplasms; Male; Methylcholanthrene; Microsomes, Liver; Middle Aged; Naphthols; Pentobarbital; Phenytoin; Tumor Cells, Cultured

1987
Colorimetric assay of urinary 5-hydroxy-3-indoleacetic acid.
    Clinical biochemistry, 1982, Volume: 15, Issue:2

    Topics: Acetaminophen; Adult; Carcinoid Tumor; Colorimetry; Humans; Hydroxyindoleacetic Acid; Mercaptoethylamines; Naphthols; Nitroso Compounds

1982
The effect of treatment with some phase II substrates on hepatic xenobiotic metabolism and the urinary excretion of metabolites of the D-glucuronic acid pathway in the rat.
    Toxicology and applied pharmacology, 1980, Mar-15, Volume: 52, Issue:3

    Topics: Acetaminophen; Animals; Biotransformation; Cytochrome P-450 Enzyme System; Diphenylacetic Acids; Enzyme Induction; Glucuronates; Glucuronosyltransferase; Guaiacol; Inactivation, Metabolic; Liver; Male; Mixed Function Oxygenases; Naphthols; Phenylacetates; Phenylpropionates; Propyl Gallate; Rats

1980
Improved fluorometric determination of acetaminophen and its conjugates with 1-nitroso-2-naphthol in whole blood and urine.
    Chemical & pharmaceutical bulletin, 1982, Volume: 30, Issue:1

    Topics: Acetaminophen; Chemical Phenomena; Chemistry; Humans; Naphthols; Nitroso Compounds; Spectrometry, Fluorescence

1982
Inhibitory effect of phloridzin and phloretin on glucuronidation of p-nitrophenol, acetaminophen and 1-naphthol: kinetic demonstration of the influence of glucuronidation metabolism on intestinal absorption in rats.
    Biochimica et biophysica acta, 1998, Oct-23, Volume: 1425, Issue:2

    Topics: Acetaminophen; Animals; Chromatography, High Pressure Liquid; Glucuronates; Glucuronidase; Intestinal Absorption; Male; Naphthols; Nitrophenols; Phloretin; Phlorhizin; Rats; Rats, Wistar

1998
Novobiocin inhibits both UDP-glucuronosyltransferase and cytochrome P450-mediated enzyme activities in pig liver microsomes.
    Veterinary research communications, 1998, Volume: 22, Issue:6

    Topics: Acetaminophen; Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Erythromycin; Glucuronosyltransferase; Male; Microsomes, Liver; Naphthols; Novobiocin; Swine; Testosterone

1998
Analysis of substances to be used as internal standards in MEKC.
    Electrophoresis, 2007, Volume: 28, Issue:11

    Topics: 4-Aminobenzoic Acid; Acetaminophen; Benzocaine; Chromatography, Micellar Electrokinetic Capillary; Ephedrine; Naphthols; Niacin; Pharmaceutical Preparations; Phenol; Reference Standards; Reproducibility of Results; Trimethoprim

2007
Caco-2 cell monolayers as a tool to study simultaneous phase II metabolism and metabolite efflux of indomethacin, paracetamol and 1-naphthol.
    International journal of pharmaceutics, 2010, Jan-04, Volume: 383, Issue:1-2

    Topics: Acetaminophen; Biological Transport; Caco-2 Cells; Humans; Indomethacin; Intestinal Absorption; Naphthols

2010