acetaminophen has been researched along with 1-naphthylisothiocyanate in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Allen, RL; Billington, D; Osypiw, JC | 1 |
| Bonk, I; Bryant, S; Klatt, M; Köpke, A; Nebrich, G; Taufmann, M; Thome-Kromer, B; Wacker, U | 1 |
| Adler, R; Amacher, DE; Herath, A; Townsend, RR | 1 |
| Kim, DH; La, S; Yoo, HH | 1 |
9 other study(ies) available for acetaminophen and 1-naphthylisothiocyanate
| Article | Year |
|---|---|
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Subpopulations of rat hepatocytes separated by Percoll density-gradient centrifugation show characteristics consistent with different acinar locations.
Topics: 1-Naphthylisothiocyanate; Acetaminophen; Alanine Transaminase; Animals; Carbon Tetrachloride; Cell Separation; Cell Survival; Cells, Cultured; Centrifugation, Density Gradient; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; L-Lactate Dehydrogenase; Liver; Malate Dehydrogenase; Male; Methotrexate; Pyruvate Kinase; Rats; Rats, Wistar | 1994 |
Toward the identification of liver toxicity markers: a proteome study in human cell culture and rats.
Topics: 1-Naphthylisothiocyanate; Acetaminophen; Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Animals; Biomarkers; Carbamoyl-Phosphate Synthase (Ammonia); Catalase; Cell Line, Tumor; Cisplatin; Databases, Protein; Dimethylnitrosamine; Electrophoresis, Gel, Two-Dimensional; Hexokinase; Humans; Indomethacin; Isoelectric Point; Liver; Male; Molecular Weight; Protein Isoforms; Proteins; Proteome; Proteomics; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetracycline | 2003 |
Use of proteomic methods to identify serum biomarkers associated with rat liver toxicity or hypertrophy.
Topics: 1-Naphthylisothiocyanate; Acetaminophen; Animals; Biomarkers; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertrophy; Liver Diseases; Male; Methylcellulose; Organ Size; Phenobarbital; Proteomics; Pyrimidines; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity | 2005 |
Liquid chromatography-mass spectrometric analysis of urinary metabolites and their pattern recognition for the prediction of drug-induced hepatotoxicity.
Topics: 1-Naphthylisothiocyanate; Acetaminophen; Algorithms; Animals; Carbon Tetrachloride; Chromatography, Liquid; Computer Simulation; Diclofenac; Liver; Male; Mass Spectrometry; Rats; Structure-Activity Relationship | 2005 |