acetaldehyde has been researched along with fomepizole in 59 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (44.07) | 18.7374 |
| 1990's | 15 (25.42) | 18.2507 |
| 2000's | 12 (20.34) | 29.6817 |
| 2010's | 6 (10.17) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Keating, JW; Peters, TJ; Preedy, VR | 1 |
| Cronholm, T | 1 |
| Kera, Y; Komura, S; Ohbora, Y | 1 |
| Israel, Y; Kera, Y; Lindros, KO; Penttilä, KE; Speisky, H | 1 |
| Amit, Z; Aragon, CM; Spivak, K | 2 |
| Geelen, MJ; Guzmán, M | 1 |
| Amit, Z; Spivak, KJ | 1 |
| Matsuda, Y; Takada, A; Yasuhara, M | 1 |
| Widenius, TV | 1 |
| Fisher-Simpson, V; Murono, EP | 1 |
| Anderson, RA; Oswald, C; Quigg, JM; Zaneveld, LJ | 1 |
| Inoue, K; Kera, Y; Kiriyama, T; Komura, S | 1 |
| Graham, TJ; Santucci, L; Van Thiel, DH | 1 |
| Heikkilä, J; Hillbom, M; Kupari, M; Lindros, K; Ylikahri, R | 1 |
| Egler, K; Gavaler, JS; Gay, V; Van Thiel, DH | 1 |
| Blakley, PM; Scott, WJ | 2 |
| Hillbom, ME; Lindros, KO; Sarviharju, MS | 1 |
| Chedid, A; Kromme, C; Mendenhall, CL | 1 |
| Ji, S; Kashiwagi, T; Lindros, KO; Thurman, RG | 1 |
| Eriksson, CJ; Härkönen, M; Leinonen, P; Widenius, TV; Ylikahri, RH | 1 |
| Belinsky, SA; Kauffman, FC; Reinke, LA; Thurman, RG | 1 |
| Lindros, KO; Sinclair, JD | 1 |
| Pösö, AR; Pösö, H | 1 |
| Oratz, M; Rothschild, MA; Schreiber, SS | 1 |
| Pösö, H | 1 |
| Marway, JS; Preedy, VR | 1 |
| Höök-Nikanne, J; Koivisto, T; Kosunen, TU; Roine, RP; Salaspuro, M; Salmela, KS | 1 |
| Färkkilä, M; Jokelainen, K; Roine, RP; Salaspuro, M; Väänänen, H | 1 |
| Baraona, E; Flisiak, R; Li, J; Lieber, CS | 1 |
| Riddle, MM; Smialowicz, RJ; Williams, WC | 1 |
| Bagby, GJ; D'Souza, NB; Deaciuc, IV; Lang, CH; Spitzer, JJ | 1 |
| Mitchell, WD; Preedy, VR; Richardson, PJ; Siddiq, T; Teare, J | 1 |
| Ameno, K; Ameno, S; Fuke, C; Ijiri, I; Kinoshita, H | 1 |
| Chiarpotto, E; Domenicotti, C; Lamedica, A; Marinari, UM; Melloni, E; Paola, D; Poli, G; Pronzato, MA; Ricciarelli, R | 1 |
| Aragno, M; Biasi, F; Camandola, S; Chiarpotto, E; Danni, O; Dianzani, MU; Poli, G; Scavazza, A; Tamagno, E | 1 |
| Abou Hashieh, I; Besson, F; Gerolami, A; Mathieu, S | 1 |
| Itälä, L; Roine, RP; Salaspuro, M; Salmela, KS; Sillanaukee, P; Väkeväinen, S | 1 |
| Altomare, E; Grattagliano, I; Signorile, A; Vendemiale, G | 1 |
| Fontana, L; Greenwel, P; Jerez, D; Rojas-Valencia, L; Rojkind, M; Solís-Herruzo, JA | 1 |
| Crabb, DW; Dorris, R; Fischer, M; Galli, A; Pinaire, J | 1 |
| Cederbaum, AI; Chen, J; Clemens, DL; Gao, B | 1 |
| Salaspuro, M; Tillonen, J; Väkeväinen, S | 1 |
| Eriksson, CJ; Iles, MR; Kohlenberg-Mueller, K; Sarkola, T | 1 |
| Ameno, K; Ameno, S; Ijiri, I; Jamal, M; Okada, N | 1 |
| Diana, M; Dosia, G; Foddai, M; Spiga, S | 1 |
| Ameno, K; Ijiri, I; Ikuo, U; Jamal, M; Kumihashi, M; Wang, W | 1 |
| Ameno, K; Ijiri, I; Jamal, M; Kumihashi, M; Uekita, I; Wang, W | 1 |
| D'Addario, C; Ming, Y; Ogren, SO; Terenius, L | 1 |
| Closon, C; Quertemont, E; Tambour, S; Tirelli, E | 1 |
| Aung, CS; Cabot, PJ; Monteith, GR; Roberts-Thomson, SJ; Venkata, NG | 1 |
| Closon, C; Didone, V; Quertemont, E; Tirelli, E | 1 |
| Chen, YT; Hung, DZ; Liao, JW | 1 |
| Monte, AA; Sande, M; Thompson, D | 1 |
| Quintanilla, ME; Tampier, L | 1 |
| Clemens, DL; Donohue, TM; Ehlers, RA; Fox, HS; Thomes, PG; Trambly, CS; Tuma, DJ | 1 |
| Izumi, Y; Tokuda, K; Zorumski, CF | 1 |
| Clemens, DL; Dey, A; Swaminathan, K | 1 |
1 trial(s) available for acetaldehyde and fomepizole
| Article | Year |
|---|---|
Ethanol, acetaldehyde, acetate, and lactate levels after alcohol intake in white men and women: effect of 4-methylpyrazole.
Topics: Acetaldehyde; Acetates; Adult; Alcohol Dehydrogenase; Breath Tests; Enzyme Inhibitors; Ethanol; Female; Fomepizole; Humans; Lactic Acid; Male; Placebos; Premenopause; Pyrazoles; Sex Characteristics | 2002 |
58 other study(ies) available for acetaldehyde and fomepizole
| Article | Year |
|---|---|
The acute effects of ethanol and acetaldehyde on rates of protein synthesis in type I and type II fibre-rich skeletal muscles of the rat.
Topics: Acetaldehyde; Animals; Cyanamide; Ethanol; Fomepizole; Muscle Proteins; Muscles; Phenylalanine; Pyrazoles; Rats | 1992 |
Ethanol-acetaldehyde exchange in vivo and in isolated hepatocytes.
Topics: Acetaldehyde; Animals; Ethanol; Female; Fomepizole; Liver; Oxidation-Reduction; Protons; Pyrazoles; Rats; Rats, Inbred Strains | 1987 |
The metabolism of acetaldehyde and not acetaldehyde itself is responsible for in vivo ethanol-induced lipid peroxidation in rats.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Animals; Ethanol; Fomepizole; Lipid Peroxidation; Male; Malondialdehyde; Pyrazoles; Rats; Rats, Inbred Strains; Xanthine Oxidase | 1988 |
Depletion of hepatic glutathione by ethanol occurs independently of ethanol metabolism.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Cyanamide; Disulfiram; Ethanol; Female; Fomepizole; Glutathione; In Vitro Techniques; Liver; Male; Pyrazoles; Rats; Rats, Inbred Strains | 1988 |
Alterations in brain aldehyde dehydrogenase activity modify ethanol-induced conditioned taste aversion.
Topics: Acetaldehyde; Animals; Conditioning, Psychological; Cyanamide; Ethanol; Fomepizole; Male; Pyrazoles; Rats; Saccharin; Taste | 1987 |
Short-term inhibition of carnitine palmitoyltransferase I activity in rat hepatocytes incubated with ethanol.
Topics: Acetaldehyde; Acyltransferases; Animals; Carnitine O-Palmitoyltransferase; Ethanol; Fomepizole; Liver; Male; Malonyl Coenzyme A; Pyrazoles; Rats; Rats, Inbred Strains | 1988 |
The role of acetaldehyde-metabolizing enzymes in the mediation of ethanol consumption: an investigation using a simulated drinking bout.
Topics: Acetaldehyde; Alcohol Drinking; Aldehyde Dehydrogenase; Animals; Cyanamide; Fomepizole; Male; Pyrazoles; Rats | 1987 |
Degradation of acetaldehyde produced by the nonalcohol dehydrogenase pathway.
Topics: Acetaldehyde; Animals; Ethanol; Fomepizole; Liver; Male; Oxidation-Reduction; Pyrazoles; Rats; Rats, Inbred Strains | 1986 |
Ethanol-induced inhibition of testosterone biosynthesis in vitro: lack of acetaldehyde effect.
Topics: Acetaldehyde; Animals; Chorionic Gonadotropin; Depression, Chemical; Dose-Response Relationship, Drug; Ethanol; Fomepizole; Leydig Cells; Male; NAD; Pyrazoles; Rats; Testosterone | 1987 |
Alterations in brain aldehyde dehydrogenase activity modify the locomotor effects produced by ethanol in rats.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Brain; Cyanamide; Ethanol; Fomepizole; Male; Motor Activity; Pyrazoles; Rats | 1987 |
Partial characterization of alcohol dehydrogenase activity in purified rat Leydig cells.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Animals; Ethanol; Fomepizole; Hydrogen-Ion Concentration; Leydig Cells; Male; NAD; Pyrazoles; Rats; Rats, Inbred Strains; Time Factors | 1986 |
Demonstration of a functional blood-testis barrier to acetaldehyde. Evidence for lack of acetaldehyde effect on ethanol-induced depression of testosterone in vivo.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Animals; Chorionic Gonadotropin; Cyanamide; Ethanol; Fomepizole; Male; Mice; Pargyline; Pyrazoles; Testis; Testosterone | 1985 |
Suppression of acetaldehyde accumulation by 4-methylpyrazole in alcohol-hypersensitive Japanese.
Topics: Acetaldehyde; Adult; Alcoholic Intoxication; Flushing; Fomepizole; Heart; Heart Rate; Humans; Male; Pyrazoles | 1985 |
Inhibition of testosterone production by rat Leydig cells with ethanol and acetaldehyde: prevention of ethanol toxicity with 4-methylpyrazole.
Topics: Acetaldehyde; Animals; Cell Line; Depression, Chemical; Ethanol; Fomepizole; In Vitro Techniques; Leydig Cell Tumor; Leydig Cells; Male; Neoplasms, Experimental; Pyrazoles; Rats; Testosterone | 1983 |
Cardiovascular effects of acetaldehyde accumulation after ethanol ingestion: their modification by beta-adrenergic blockade and alcohol dehydrogenase inhibition.
Topics: Acetaldehyde; Adult; Alcohol Dehydrogenase; Alcohol Drinking; Alcohol Oxidoreductases; Alcoholic Intoxication; Blood Pressure; Cardiac Output; Cyanamide; Cyanides; Echocardiography; Ethanol; Fomepizole; Heart Rate; Hemodynamics; Humans; Male; Propranolol; Pyrazoles | 1983 |
Evaluation of the differential in vivo toxic effects of ethanol and acetaldehyde on the hypothalamic-pituitary-gonadal axis using 4-methylpyrazole.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Ethanol; Fomepizole; Hypothalamo-Hypophyseal System; Luteinizing Hormone; Male; Organ Size; Pyrazoles; Rats; Rats, Inbred Strains; Testis; Testosterone | 1983 |
Determination of the proximate teratogen of the mouse fetal alcohol syndrome. 1. Teratogenicity of ethanol and acetaldehyde.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Body Weight; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Fetal Death; Fetal Resorption; Fomepizole; Gestational Age; Mice; Pregnancy; Pyrazoles; Teratogens | 1984 |
Potentiation of ethanol toxicity by cyanamide in relation to acetaldehyde accumulation.
Topics: Acetaldehyde; Animals; Cyanamide; Cyanides; Drug Synergism; Ethanol; Fomepizole; Lethal Dose 50; Male; Pyrazoles; Rats | 1983 |
Altered proline uptake by mouse liver cells after chronic exposure to ethanol and its metabolites.
Topics: Acetaldehyde; Animals; Cell Division; Clone Cells; Ethanol; Fomepizole; Liver; Mice; Proline; Pyrazoles | 1984 |
Determination of the proximate teratogen of the mouse fetal alcohol syndrome. 2. Pharmacokinetics of the placental transfer of ethanol and acetaldehyde.
Topics: Acetaldehyde; Animals; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Fetal Blood; Fomepizole; Kinetics; Liver; Maternal-Fetal Exchange; Mice; Pregnancy; Pyrazoles | 1984 |
Aldehyde dehydrogenase-dependent acetaldehyde metabolism in periportal and pericentral regions of the perfused rat liver.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Animals; Female; Fluorescence; Fomepizole; Liver; NAD; Portal System; Pyrazoles; Rats; Rats, Inbred Strains | 1983 |
Inhibition of testosterone biosynthesis by ethanol. Relation to hepatic and testicular acetaldehyde, ketone bodies and cytosolic redox state in rats.
Topics: Acetaldehyde; Animals; Cytosol; Ethanol; Fomepizole; Ketone Bodies; Liver; Male; Oxidation-Reduction; Pentobarbital; Pyrazoles; Rats; Testis; Testosterone | 1983 |
Interactions between ethanol metabolism and mixed-function oxidation in perfused rat liver: inhibition of p-nitroanisole O-demethylation.
Topics: Acetaldehyde; Alcohol Oxidoreductases; Animals; Anisoles; Aspartic Acid; Ethanol; Female; Fomepizole; In Vitro Techniques; Liver; Microsomes, Liver; Mixed Function Oxygenases; NADP; Nitroanisole O-Demethylase; Oxidoreductases; Perfusion; Pyrazoles; Rats | 1980 |
Suppression of alcohol drinking with brain aldehyde dehydrogenase inhibition.
Topics: Acetaldehyde; Alcohol Drinking; Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Animals; Brain; Cyanamide; Drug Interactions; Fomepizole; Male; Pyrazoles; Rats; Time Factors | 1981 |
Inhibition of ornithine decarboxylase in regenerating rat liver by acute ethanol treatment.
Topics: Acetaldehyde; Alanine Transaminase; Animals; Carboxy-Lyases; Disulfiram; Ethanol; Female; Fomepizole; Hepatectomy; Kidney; Liver; Liver Regeneration; Ornithine Decarboxylase Inhibitors; Pyrazoles; Rats | 1980 |
Ethanol effects on albumin sythesis.
Topics: Acetaldehyde; Animals; Arginine; Ethanol; Fomepizole; In Vitro Techniques; Liver; Male; Ornithine; Perfusion; Polyribosomes; Pyrazoles; Rabbits; Serum Albumin; Spermine; Urea | 1980 |
Inhibition of ornithine decarboxylase in the stomach and small intestine of rat by a single dose of ethanol.
Topics: Acetaldehyde; Animals; Carboxy-Lyases; Cycloheximide; Duodenum; Ethanol; Fomepizole; Jejunum; Male; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Pyrazoles; Rats; Stomach | 1980 |
The acute effects of ethanol and acetaldehyde on the synthesis of mixed and contractile proteins of the jejunum.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholic Intoxication; Aldehyde Dehydrogenase; Animals; Contractile Proteins; Cyanamide; Ethanol; Fomepizole; Gastrointestinal Motility; Jejunum; Male; Muscle Proteins; Muscle, Smooth; Pyrazoles; Rats; Rats, Wistar | 1995 |
Characteristics of Helicobacter pylori alcohol dehydrogenase.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Cell Division; Fomepizole; Helicobacter pylori; Isoelectric Focusing; Pyrazoles; Staining and Labeling | 1993 |
In vitro acetaldehyde formation by human colonic bacteria.
Topics: Acetaldehyde; Adult; Aged; Bacteria; Colon; Ethanol; Female; Fomepizole; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Pyrazoles | 1994 |
Effects of ethanol on prostanoid production by liver fat-storing cells.
Topics: 6-Ketoprostaglandin F1 alpha; Acetaldehyde; Alcohol Dehydrogenase; Animals; Cytosol; Dinoprostone; Disulfiram; Epoprostenol; Ethanol; Fomepizole; Isoenzymes; Lipid Metabolism; Liver; Male; Pyrazoles; Rats; Rats, Sprague-Dawley | 1993 |
Methoxyacetaldehyde, an intermediate metabolite of 2-methoxyethanol, is immunosuppressive in the rat.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Animals; Antibody Formation; Cyanamide; Disulfiram; Ethylene Glycols; Fomepizole; Immune Tolerance; Lipopolysaccharides; Male; Pyrazoles; Rats; Rats, Inbred F344; Solvents | 1993 |
Ethanol alters the metabolic response of isolated perfused rat liver to a phagocytic stimulus.
Topics: Acetaldehyde; Animals; Blood Glucose; Culture Techniques; Endothelium, Vascular; Energy Metabolism; Ethanol; Fomepizole; Indomethacin; Kupffer Cells; Lactates; Lactic Acid; Liver; Liver Glycogen; Male; Oxygen Consumption; Perfusion; Phagocytosis; Prostaglandins; Pyrazoles; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar | 1993 |
Ethanol-induced inhibition of ventricular protein synthesis in vivo and the possible role of acetaldehyde.
Topics: Acetaldehyde; Animals; Cardiomyopathy, Alcoholic; Cyanamide; Depression, Chemical; Ethanol; Fomepizole; Heart Ventricles; Male; Muscle Proteins; Protein Synthesis Inhibitors; Pyrazoles; Rats; Rats, Wistar | 1993 |
Additional proof of reduction of ethanol absorption from rat intestine in vivo by high acetaldehyde concentrations.
Topics: Acetaldehyde; Animals; Cyanamide; Ethanol; Fomepizole; Intestinal Absorption; Pyrazoles; Rats; Rats, Wistar | 1995 |
Effects of ethanol metabolism on PKC activity in isolated rat hepatocytes.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Animals; Enzyme Inhibitors; Ethanol; Fomepizole; Immunoblotting; Isoenzymes; Liver; Male; Protein Kinase C; Pyrazoles; Rats; Rats, Wistar | 1996 |
Acetaldehyde involvement in ethanol-induced potentiation of rat hepatocyte damage due to the carcinogen 1,2-dibromoethane.
Topics: Acetaldehyde; Analysis of Variance; Animals; Carcinogens; Drug Synergism; Ethanol; Ethylene Dibromide; Fomepizole; Glutathione Transferase; In Vitro Techniques; Lipid Peroxidation; Liver; Male; Pyrazoles; Rats; Rats, Wistar; Time Factors | 1995 |
Inhibition of gap junction intercellular communications of cultured rat hepatocytes by ethanol: role of ethanol metabolism.
Topics: 1-Octanol; Acetaldehyde; Animals; Cell Communication; Cell Membrane; Cells, Cultured; Central Nervous System Depressants; Connexins; Ethanol; Fluorescent Antibody Technique, Indirect; Fluorescent Dyes; Fomepizole; Gap Junction beta-1 Protein; Gap Junctions; Hydrogen-Ion Concentration; Isoquinolines; Liver; Male; Microscopy, Electron; Octanols; Pyrazoles; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence | 1996 |
Binding of acetaldehyde to rat gastric mucosa during ethanol oxidation.
Topics: Acetaldehyde; Acetates; Alcohol Dehydrogenase; Animals; Azides; Carbon Radioisotopes; Ethanol; Fomepizole; Gastric Mucosa; Kinetics; Male; Protein Binding; Proteins; Pyrazoles; Radioisotope Dilution Technique; Rats; Rats, Wistar; Sodium Azide | 1997 |
Ethanol-induced changes of intracellular thiol compartmentation and protein redox status in the rat liver: effect of tauroursodeoxycholate.
Topics: Acetaldehyde; Alcohol Drinking; Animals; Cell Nucleus; Cyanamide; Cytosol; Ethanol; Fomepizole; Glutathione; Kinetics; Liver; Male; Malondialdehyde; Mitochondria, Liver; Oxidation-Reduction; Proteins; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Taurochenodeoxycholic Acid | 1998 |
Ethanol induces the expression of alpha 1(I) procollagen mRNA in a co-culture system containing a liver stellate cell-line and freshly isolated hepatocytes.
Topics: Acetaldehyde; Animals; Cells, Cultured; Ethanol; Fibronectins; Fomepizole; Gene Expression Regulation, Enzymologic; Liver; Male; Procollagen; Pyrazoles; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription, Genetic | 1997 |
The transcriptional and DNA binding activity of peroxisome proliferator-activated receptor alpha is inhibited by ethanol metabolism. A novel mechanism for the development of ethanol-induced fatty liver.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Cells, Cultured; Cyanamide; DNA; DNA-Binding Proteins; Ethanol; Fomepizole; Genes, Reporter; Liver; Male; Nuclear Proteins; Protein Binding; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 2001 |
Ethanol inhibits the JAK-STAT signaling pathway in freshly isolated rat hepatocytes but not in cultured hepatocytes or HepG2 cells: evidence for a lack of involvement of ethanol metabolism.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Animals; Cell Division; Cells, Cultured; Collagen; Cytochrome P-450 CYP2E1; Enzyme Inhibitors; Ethanol; Fomepizole; Hepatocytes; Hydrogen Peroxide; Interferon-gamma; Interleukin-6; Male; Protein-Tyrosine Kinases; Pyrazoles; Rats; Rats, Sprague-Dawley; Signal Transduction; Transcription Factors | 2001 |
4-Methylpyrazole decreases salivary acetaldehyde levels in aldh2-deficient subjects but not in subjects with normal aldh2.
Topics: Acetaldehyde; Adult; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Blood Pressure; Ethanol; Female; Fomepizole; Heart Rate; Humans; Kinetics; Male; Metabolic Clearance Rate; Pyrazoles; Saliva; Skin Temperature | 2001 |
In vivo study of salsolinol produced by a high concentration of acetaldehyde in the striatum and nucleus accumbens of free-moving rats.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Cyanamide; Dopamine; Dose-Response Relationship, Drug; Ethanol; Fomepizole; Isoquinolines; Male; Microdialysis; Nucleus Accumbens; Pyrazoles; Rats; Rats, Wistar; Serotonin | 2003 |
Acetaldehyde increases dopaminergic neuronal activity in the VTA.
Topics: Acetaldehyde; Action Potentials; Animals; Dopamine; Dose-Response Relationship, Drug; Ethanol; Fomepizole; Male; Neurons; Pyrazoles; Rats; Rats, Sprague-Dawley; Ventral Tegmental Area | 2004 |
Ethanol and acetaldehyde: in vivo quantitation and effects on cholinergic function in rat brain.
Topics: Acetaldehyde; Alcohol Drinking; Animals; Blotting, Western; Brain; Catalase; Choline O-Acetyltransferase; Cyanamide; Ethanol; Fomepizole; Male; Microdialysis; Pyrazoles; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction | 2007 |
Catalase mediates acetaldehyde formation in the striatum of free-moving rats.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Amitrole; Animals; Basal Ganglia; Catalase; Chromatography, Gas; Cyanamide; Enzyme Inhibitors; Ethanol; Fomepizole; Locomotion; Male; Microdialysis; Oxidation-Reduction; Pyrazoles; Rats; Rats, Wistar; Sodium Azide; Time Factors | 2007 |
The role of acetaldehyde in mediating effects of alcohol on expression of endogenous opioid system genes in a neuroblastoma cell line.
Topics: Acetaldehyde; Cell Line, Tumor; Cell Survival; Ethanol; Fomepizole; Gene Expression Regulation; Humans; Neuroblastoma; Pyrazoles; Receptors, Opioid; Reverse Transcriptase Polymerase Chain Reaction | 2008 |
Effects of cyanamide and acetaldehyde accumulation on the locomotor stimulant and sedative effects of ethanol in mice.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Animals; Brain; Cyanamide; Dose-Response Relationship, Drug; Ethanol; Fomepizole; Hypnotics and Sedatives; Male; Mice; Motor Activity; Pyrazoles; Reflex | 2007 |
PPARalpha and PPARbeta are differentially affected by ethanol and the ethanol metabolite acetaldehyde in the MCF-7 breast cancer cell line.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Aldehyde Oxidoreductases; Breast Neoplasms; Cell Line, Tumor; Cyanamide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanol; Female; Fomepizole; Gene Expression Regulation, Neoplastic; Humans; PPAR alpha; PPAR-beta; Pyrazoles; RNA, Messenger; Thiazoles; Transcription, Genetic; Transcriptional Activation; Transfection | 2008 |
Acetaldehyde and the hypothermic effects of ethanol in mice.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Animals; Body Temperature; Central Nervous System Depressants; Cyanamide; Drug Synergism; Enzyme Inhibitors; Ethanol; Female; Fomepizole; Hypothermia; Liver; Mice; Pyrazoles | 2009 |
Protective effects of fomepizole on 2-chloroethanol toxicity.
Topics: Acetaldehyde; Acetylcysteine; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Antidotes; Antioxidants; Disulfiram; Drug Synergism; Enzyme Inhibitors; Ethylene Chlorohydrin; Fomepizole; Glutathione; Kidney; Lethal Dose 50; Liver; Male; Pyrazoles; Rats; Rats, Sprague-Dawley; Solvents | 2010 |
Fomepizole for severe disulfiram-ethanol reactions.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Antidotes; Disulfiram; Drug Interactions; Ethanol; Female; Flushing; Fomepizole; Humans; Hypotension; Middle Aged; Pyrazoles; Tachycardia; Young Adult | 2012 |
Place conditioning with ethanol in rats bred for high (UChB) and low (UChA) voluntary alcohol drinking.
Topics: Acetaldehyde; Alcohol Drinking; Aldehyde Dehydrogenase; Animals; Breeding; Conditioning, Psychological; Enzyme Inhibitors; Ethanol; Female; Fomepizole; Pyrazoles; Rats; Reinforcement, Psychology; Self Administration | 2011 |
Multilevel regulation of autophagosome content by ethanol oxidation in HepG2 cells.
Topics: Acetaldehyde; Autophagy; Ethanol; Fomepizole; Glutathione; Hep G2 Cells; Hepatocytes; Humans; Lysosomal Membrane Proteins; Microtubule-Associated Proteins; Models, Biological; Oxidation-Reduction; Phagosomes; Pyrazoles; RNA, Messenger; Vacuoles | 2013 |
Locally-generated acetaldehyde is involved in ethanol-mediated LTP inhibition in the hippocampus.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Allyl Compounds; Animals; CA1 Region, Hippocampal; Catalase; Cytochrome P-450 CYP2E1 Inhibitors; Ethanol; Excitatory Postsynaptic Potentials; Fomepizole; In Vitro Techniques; Long-Term Potentiation; Male; Pyramidal Cells; Pyrazoles; Rats; Sodium Azide; Sulfides | 2013 |
Inhibition of CYP2E1 leads to decreased malondialdehyde-acetaldehyde adduct formation in VL-17A cells under chronic alcohol exposure.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Allyl Compounds; Apoptosis; Caspase 3; Cell Line; Cell Survival; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Drug Administration Schedule; Enzyme Inhibitors; Ethanol; Fomepizole; Hep G2 Cells; Humans; Malondialdehyde; Pyrazoles; Reactive Oxygen Species; Sulfides | 2013 |