acetaldehyde and deoxyguanosine

acetaldehyde has been researched along with deoxyguanosine in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.13)18.7374
1990's5 (15.63)18.2507
2000's17 (53.13)29.6817
2010's9 (28.13)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chung, FL; Hecht, SS; Palladino, G1
Bogdanffy, MS; Kuykendall, JR1
Fang, JL; Schweda, EK; Vaca, CE1
Ohya, T1
Crane, AE; Steiner, S; Watson, WP1
Chung, FL; Foiles, PG; Kuśmierek, JT; Miglietta, LM; Nishikawa, A; Singer, B1
Cheng, G; Hecht, SS; McIntee, EJ; Shi, Y; Villalta, PW; Wang, M2
Hecht, SS; McIntee, EJ; Wang, M1
Cheng, G; Hecht, SS; Jalas, JR; McIntee, EJ; Shi, Y; Sturla, SJ; Villalta, PW; Wang, M1
Barnes, SL; Singletary, KW; van Breemen, RB1
Chao, FH; Li, GX; Liu, HL; Sun, YM; Xi, ZG; Yang, DF; Yang, YH; Zhang, HS; Zhang, W1
Cai, H; Daniels, JS; Guengerich, FP; Marnett, LJ; Osheroff, N; Riggins, JN; Vélez-Cruz, R1
Brooks, PJ; Dizdaroglu, M; Jaruga, P; Nath, RG; Theruvathu, JA1
An, SM; Chae, SY; Cho, HY; Choi, YW; Kim, HS; Kim, SS; Kwack, SJ; Lee, BM; Lee, RD; Park, CH; Park, KL; Rhee, GS; Seok, JH1
Castro, GD; Castro, JA; de Castro, CR; de Ferreyra, EC; Fanelli, SL; Gómez, MI; Maciel, ME1
Cho, YJ; Harris, TM; Jacob, J; Kozekov, ID; Kurtz, AJ; Lloyd, RS; Rizzo, CJ; Smith, J; Stone, MP; Voehler, M; Wang, H1
Chen, L; Hecht, SS; Hochalter, JB; Villalta, PW; Wang, M; Yu, N1
Isse, T; Kawamoto, T; Kim, H; Kim, YD; Kinaga, T; Kunugita, N; Matsumoto, A; Narai, R; Ogawa, M; Oyama, T; Uchiyama, I; Yamaguchi, T1
Hecht, SS; Lao, Y; Moriya, M; Stein, S; Yang, IY1
Hecht, SS; Villalta, PW; Wang, M; Zhang, S1
Guza, R; Jones, R; Li, ZZ; Matter, B; Tretyakova, N; Zhao, J1
Farmer, PB; Juren, T; Kaur, B; Sandhu, J; Segerbäck, D; Singh, R; Steward, WP1
Esaka, Y; Murakami, H; Uno, B1
Angeli, JP; de Oliveira, TF; Di Mascio, P; Freitas, FP; Garcia, CC; Gomes, OF; Loureiro, AP; Medeiros, MH1
Balbo, S; Bliss, RL; Hatsukami, DK; Hecht, SS; Jensen, JA; Meng, L1
Chiba, T; Hori, K; Matsuda, T; Miyamoto, S; Muto, M; Yukawa, Y1
Chiba, T; Hori, K; Matsuda, T; Muto, M; Nagayoshi, H; Yokoyama, A; Yukawa, Y1
Cordell, R; Farmer, PB; Gromadzinska, J; Juren, T; Mistry, Y; Segerbäck, D; Singh, R1
Bodnar, WM; Green, A; Moeller, BC; Recio, L; Sun, W; Swenberg, JA; Wright, FA1
Di Mascio, P; Freitas, FP; Garcia, CC; Medeiros, MH; Sanchez, AB1
Baker, EJ; Balbo, S; Daunais, JB; Grant, KA; Juanes, RC; Khariwala, S1

Other Studies

32 other study(ies) available for acetaldehyde and deoxyguanosine

ArticleYear
Formation of cyclic nucleic acid adducts from some simple alpha, beta-unsaturated carbonyl compounds and cyclic nitrosamines.
    IARC scientific publications, 1986, Issue:70

    Topics: Acetaldehyde; Acrolein; Animals; Biotransformation; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Deoxyguanosine; Esterases; Magnetic Resonance Spectroscopy; Models, Chemical; N-Nitrosopyrrolidine; Nitrosamines; Spectrum Analysis; Swine

1986
Formation and stability of acetaldehyde-induced crosslinks between poly-lysine and poly-deoxyguanosine.
    Mutation research, 1994, Nov-01, Volume: 311, Issue:1

    Topics: Acetaldehyde; Cross-Linking Reagents; Deoxyguanosine; Kinetics; Polylysine; Polymers

1994
Studies of the reaction of acetaldehyde with deoxynucleosides.
    Chemico-biological interactions, 1995, Oct-20, Volume: 98, Issue:1

    Topics: Acetaldehyde; Chromatography, High Pressure Liquid; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Deoxyribonucleosides; Drug Stability; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Ultraviolet; Temperature

1995
Reaction of malondialdehyde with deoxyribonucleosides in the presence of acetaldehyde.
    Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:10

    Topics: Acetaldehyde; Adenosine; Chromatography, High Pressure Liquid; Deoxycytidine; Deoxyguanosine; Deoxyribonucleosides; Hydrogen-Ion Concentration; Malondialdehyde; Spectrophotometry, Ultraviolet

1994
32P-postlabelling methods for cyclic DNA adducts.
    IARC scientific publications, 1993, Issue:124

    Topics: Acetaldehyde; Animals; Carcinogens; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA; DNA Damage; Male; Mice; Mice, Inbred C3H; Nucleotides, Cyclic; Phosphorus Radioisotopes; Skin

1993
Development of monoclonal antibodies specific for 1,N2-ethenodeoxyguanosine and N2,3-ethenodeoxyguanosine and their use for quantitation of adducts in G12 cells exposed to chloroacetaldehyde.
    Carcinogenesis, 1993, Volume: 14, Issue:1

    Topics: Acetaldehyde; Animals; Antibodies, Monoclonal; Cells, Cultured; Cricetinae; Cricetulus; Deoxyguanosine; DNA Damage; DNA, Single-Stranded; Enzyme-Linked Immunosorbent Assay; Female; Lipid Peroxidation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL

1993
Identification of DNA adducts of acetaldehyde.
    Chemical research in toxicology, 2000, Volume: 13, Issue:11

    Topics: Acetaldehyde; Aldehydes; Animals; Cattle; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA; DNA Adducts; Nuclear Magnetic Resonance, Biomolecular; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet

2000
Reactions of 2,6-dimethyl-1,3-dioxane-4-ol (aldoxane) with deoxyguanosine and DNA.
    Chemical research in toxicology, 2001, Volume: 14, Issue:8

    Topics: Acetaldehyde; Carcinogens; Chromatography, High Pressure Liquid; Deoxyguanosine; Dioxanes; DNA; DNA Adducts; Guanine; Magnetic Resonance Spectroscopy

2001
New DNA adducts of crotonaldehyde and acetaldehyde.
    Toxicology, 2001, Sep-14, Volume: 166, Issue:1-2

    Topics: Acetaldehyde; Aldehydes; Carcinogens; Chemical Phenomena; Chemistry; Deoxyguanosine; DNA Adducts; Humans; Neoplasms

2001
Reactions of formaldehyde plus acetaldehyde with deoxyguanosine and DNA: formation of cyclic deoxyguanosine adducts and formaldehyde cross-links.
    Chemical research in toxicology, 2003, Volume: 16, Issue:2

    Topics: Acetaldehyde; Animals; Cattle; Cross-Linking Reagents; Cyclization; Deoxyguanosine; DNA; DNA Adducts; Dose-Response Relationship, Drug; Formaldehyde; Humans; Nuclear Magnetic Resonance, Biomolecular; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Stereoisomerism

2003
Ethanol inhibits benzo[a]pyrene-DNA adduct removal and increases 8-oxo-deoxyguanosine formation in human mammary epithelial cells.
    Cancer letters, 2004, Jan-20, Volume: 203, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetaldehyde; Benzo(a)pyrene; Breast Neoplasms; Cell Line, Tumor; Deoxyguanosine; DNA Adducts; DNA Damage; Epithelial Cells; Ethanol; Humans; Mammary Glands, Human; Oxidative Stress; Oxygen; Time Factors

2004
[The effects of DNA damage induced by acetaldehyde].
    Huan jing ke xue= Huanjing kexue, 2004, Volume: 25, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetaldehyde; Adult; Animals; Chromatography, High Pressure Liquid; Comet Assay; Deoxyguanosine; DNA Damage; Environmental Pollutants; Humans; Lymphocytes; Male; Rats

2004
Exocyclic DNA lesions stimulate DNA cleavage mediated by human topoisomerase II alpha in vitro and in cultured cells.
    Biochemistry, 2005, Mar-15, Volume: 44, Issue:10

    Topics: Acetaldehyde; Alkylating Agents; Antigens, Neoplasm; Cell Line, Tumor; Cell Survival; Deoxyguanosine; DNA Adducts; DNA Damage; DNA Repair; DNA Topoisomerases, Type II; DNA-Binding Proteins; Histone-Lysine N-Methyltransferase; Humans; Myeloid-Lymphoid Leukemia Protein; Proto-Oncogenes; Transcription Factors

2005
Polyamines stimulate the formation of mutagenic 1,N2-propanodeoxyguanosine adducts from acetaldehyde.
    Nucleic acids research, 2005, Volume: 33, Issue:11

    Topics: Acetaldehyde; Aldehydes; Deoxyguanosine; DNA Adducts; Gas Chromatography-Mass Spectrometry; Humans; Mutagenesis; Spermidine

2005
Neurotoxic effects of alcohol and acetaldehyde during embryonic development.
    Journal of toxicology and environmental health. Part A, 2005, Dec-10, Volume: 68, Issue:23-24

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetaldehyde; Animals; Antioxidants; Catalase; Cells, Cultured; Deoxyguanosine; DNA; Dose-Response Relationship, Drug; Embryo Culture Techniques; Embryo, Mammalian; Embryonic Development; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Mesencephalon; Pregnancy; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Reactive Oxygen Species; Tumor Suppressor Protein p53

2005
Ethanol-induced oxidative stress and acetaldehyde formation in rat mammary tissue: potential factors involved in alcohol drinking promotion of breast cancer.
    Toxicology, 2006, Feb-15, Volume: 219, Issue:1-3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetaldehyde; Alcohol Drinking; Animals; Breast Neoplasms; Central Nervous System Depressants; Cytosol; Deoxyguanosine; Diet; Ethanol; Female; Fluorescent Dyes; Free Radicals; Humans; Immunohistochemistry; Mammary Glands, Animal; Microscopy, Electron, Transmission; Microsomes; Oxidative Stress; Phenols; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Sulfoxides; Xanthine Oxidase; Xylenes

2006
Stereospecific formation of interstrand carbinolamine DNA cross-links by crotonaldehyde- and acetaldehyde-derived alpha-CH3-gamma-OH-1,N2-propano-2'-deoxyguanosine adducts in the 5'-CpG-3' sequence.
    Chemical research in toxicology, 2006, Volume: 19, Issue:2

    Topics: Acetaldehyde; Aldehydes; Animals; Carbon Isotopes; Chlorocebus aethiops; COS Cells; CpG Islands; Cross-Linking Reagents; Deoxyguanosine; DNA; DNA Adducts; Hydrogen Bonding; Hydrogen-Ion Concentration; Isotope Labeling; Methanol; Models, Molecular; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oligodeoxyribonucleotides; Stereoisomerism; Substrate Specificity; Temperature; Time Factors

2006
Identification of an acetaldehyde adduct in human liver DNA and quantitation as N2-ethyldeoxyguanosine.
    Chemical research in toxicology, 2006, Volume: 19, Issue:2

    Topics: Acetaldehyde; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA; DNA Adducts; Humans; Liver; Molecular Structure; Spectrometry, Mass, Electrospray Ionization; Time Factors

2006
Urinary 8-hydoxydeoxyguanosine (8-OHdG) and plasma malondialdehyde (MDA) levels in Aldh2 knock-out mice under acetaldehyde exposure.
    Industrial health, 2006, Volume: 44, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetaldehyde; Animals; Deoxyguanosine; Japan; Male; Malondialdehyde; Mice; Mice, Knockout; Polymorphism, Genetic

2006
Genotoxicity of acetaldehyde- and crotonaldehyde-induced 1,N2-propanodeoxyguanosine DNA adducts in human cells.
    Mutation research, 2006, Sep-19, Volume: 608, Issue:1

    Topics: Acetaldehyde; Aldehydes; Cell Line; Deoxyguanosine; DNA Adducts; DNA Damage; Humans; Mutagens; Oligonucleotides; Plasmids; Point Mutation; Stereoisomerism; Transfection; Xeroderma Pigmentosum

2006
Analysis of crotonaldehyde- and acetaldehyde-derived 1,n(2)-propanodeoxyguanosine adducts in DNA from human tissues using liquid chromatography electrospray ionization tandem mass spectrometry.
    Chemical research in toxicology, 2006, Volume: 19, Issue:10

    Topics: Acetaldehyde; Aldehydes; Chromatography, Liquid; Deoxyguanosine; DNA Adducts; Humans; Liver; Lung; Molecular Structure; Spectrometry, Mass, Electrospray Ionization

2006
Sequence distribution of acetaldehyde-derived N2-ethyl-dG adducts along duplex DNA.
    Chemical research in toxicology, 2007, Volume: 20, Issue:10

    Topics: 5-Methylcytosine; Acetaldehyde; Base Sequence; Capillary Electrochromatography; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA Adducts; DNA Mutational Analysis; Genes, p53; Genes, ras; Humans; Molecular Sequence Data; Mutation; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2007
Evaluation of the DNA damaging potential of cannabis cigarette smoke by the determination of acetaldehyde derived N2-ethyl-2'-deoxyguanosine adducts.
    Chemical research in toxicology, 2009, Volume: 22, Issue:6

    Topics: Acetaldehyde; Adult; Cannabis; Carcinogens; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA; DNA Adducts; DNA Damage; Humans; Lung; Male; Marijuana Smoking; Middle Aged; Spectrometry, Mass, Electrospray Ionization

2009
Structural and spectral characteristics of the cross-linked dimer derived from electrooxidation of cyclic 1,N2-propanoguanosine.
    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2011, Volume: 27, Issue:3

    Topics: Acetaldehyde; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Deoxyguanosine; Dimerization; DNA Adducts; Guanosine; Hydrogen Bonding; Mass Spectrometry; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Oxidation-Reduction; Spectrophotometry, Ultraviolet

2011
[13C2]-Acetaldehyde promotes unequivocal formation of 1,N2-propano-2'-deoxyguanosine in human cells.
    Journal of the American Chemical Society, 2011, Jun-22, Volume: 133, Issue:24

    Topics: Acetaldehyde; Cell Line; Deoxyguanosine; DNA Adducts; Humans; Phenylhydrazines; Volatilization

2011
Kinetics of DNA adduct formation in the oral cavity after drinking alcohol.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2012, Volume: 21, Issue:4

    Topics: Acetaldehyde; Adult; Alcohol Drinking; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA Adducts; DNA Damage; Female; Humans; Kinetics; Male; Mouth; Prognosis; Spectrometry, Mass, Electrospray Ionization; Young Adult

2012
Stability of acetaldehyde-derived DNA adduct in vitro.
    Biochemical and biophysical research communications, 2012, Jul-13, Volume: 423, Issue:4

    Topics: Acetaldehyde; Carcinogens; Cell Culture Techniques; Cell Transformation, Neoplastic; Deoxyguanosine; DNA Adducts; Half-Life; HL-60 Cells; Humans

2012
Combination of ADH1B*2/ALDH2*2 polymorphisms alters acetaldehyde-derived DNA damage in the blood of Japanese alcoholics.
    Cancer science, 2012, Volume: 103, Issue:9

    Topics: Acetaldehyde; Adult; Alcohol Dehydrogenase; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Alleles; Asian People; Deoxyguanosine; DNA Adducts; DNA Damage; Genotype; Humans; Japan; Middle Aged; Polymorphism, Single Nucleotide

2012
Detection of acetaldehyde derived N(2)-ethyl-2'-deoxyguanosine in human leukocyte DNA following alcohol consumption.
    Mutation research, 2012, Sep-01, Volume: 737, Issue:1-2

    Topics: Acetaldehyde; Adult; Alcohol Drinking; Chromatography, Liquid; Deoxyguanosine; DNA; DNA Adducts; Humans; Leukocytes; Male; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Time Factors; Young Adult

2012
Biomarkers of exposure and effect in human lymphoblastoid TK6 cells following [13C2]-acetaldehyde exposure.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 133, Issue:1

    Topics: Acetaldehyde; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Carbon Isotopes; Cell Culture Techniques; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA Adducts; Dose-Response Relationship, Drug; Environmental Exposure; Flow Cytometry; Genotype; Humans; Micronuclei, Chromosome-Defective; Reference Standards; Reproducibility of Results; Tandem Mass Spectrometry

2013
Elevated α-methyl-γ-hydroxy-1,N2-propano-2'-deoxyguanosine levels in urinary samples from individuals exposed to urban air pollution.
    Chemical research in toxicology, 2013, Nov-18, Volume: 26, Issue:11

    Topics: Acetaldehyde; Adolescent; Adult; Air Pollutants; Aldehydes; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA; DNA Adducts; Humans; Male; Middle Aged; Smoking; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Vehicle Emissions; Young Adult

2013
Increased levels of the acetaldehyde-derived DNA adduct N 2-ethyldeoxyguanosine in oral mucosa DNA from Rhesus monkeys exposed to alcohol.
    Mutagenesis, 2016, Volume: 31, Issue:5

    Topics: Acetaldehyde; Alcohol Drinking; Animals; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA Adducts; DNA Damage; Esophageal Mucosa; Female; Macaca mulatta; Male; Mammary Glands, Animal; Mouth Mucosa; Tandem Mass Spectrometry

2016