acetaldehyde has been researched along with cyanamide in 131 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 66 (50.38) | 18.7374 |
1990's | 32 (24.43) | 18.2507 |
2000's | 25 (19.08) | 29.6817 |
2010's | 7 (5.34) | 24.3611 |
2020's | 1 (0.76) | 2.80 |
Authors | Studies |
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Brien, JF; Loomis, CW; Peachey, JE; Rogers, BJ | 2 |
Hellström, E; Tottmar, O | 1 |
Marchner, H; Tottmar, O | 1 |
Goto, M; Kamiyama, T; Liu, J; Marumo, F; Miyakawa, H; Sato, C; Tajiri, K | 1 |
Gilani, S; Persaud, TV | 1 |
Keating, JW; Peters, TJ; Preedy, VR | 1 |
Johnsen, J; Mørland, J; Stowell, A | 1 |
Amit, Z; Aragon, CM; Rogan, F | 1 |
Lin, RC; Lumeng, L | 2 |
Zimatkin, SM | 1 |
Casini, A; Cunningham, M; Lieber, CS; Rojkind, M | 1 |
Amit, Z; Aragon, CM; Stotland, LM | 1 |
DeMaster, EG; Goon, DJ; Nagasawa, HT; Redfern, B; Shirota, FN | 1 |
Moore, DR; Rikans, LE; Snowden, CD | 1 |
Berger, MR; Einecke, H; Garzon, FT; Koch, A; Maiwald, M; Peters, TJ; Rideout, JM; Seitz, HK; Simanowski, UA | 1 |
Fillenwarth, MJ; Lin, RC; Lumeng, L; Minter, R | 1 |
Chakraborty, J; Ryle, PR; Thomson, AD | 1 |
Iannucci, J; Israel, BC; Marino, KA; Smith, CM | 1 |
Ide, H; Nakazawa, Y | 1 |
Cao, QN; Tu, GC; Weiner, H | 1 |
Israel, Y; MacDonald, A; Niemelä, O; Waks, T | 1 |
Israel, Y; Kera, Y; Lindros, KO; Penttilä, KE; Speisky, H | 1 |
Amit, Z; Aragon, CM; Spivak, K | 2 |
Hillbom, M; Jones, AW; Neiman, J | 2 |
Ali, F; Persaud, TV | 1 |
Grunnet, N; Vind, C | 1 |
Amit, Z; Spivak, KJ | 1 |
Johnsen, J; Mørland, J; Ripel, A; Stowell, A | 1 |
Carmichael, FJ; Giles, HG; Israel, Y; Meggiorini, S; Orrego, H; Saldivia, V | 1 |
Burka, LT; Ghanayem, BI; Matthews, HB | 1 |
Elberling, JE; Nagasawa, HT; Roberts, JC | 1 |
Benthin, G; Hillbom, M; Jones, AW; Löwbeer, C; Neiman, J; Sippel, H | 1 |
Solomon, LR | 1 |
Beermann, B; Edelstam, C | 1 |
Svanas, GW; Weiner, H | 1 |
Donohue, TM; Medina, VA; Sorrell, MF; Tuma, DJ | 1 |
Anderson, RA; Oswald, C; Quigg, JM; Zaneveld, LJ | 1 |
Fujiwara, M; Higashi, T; Hobara, N; Kobayashi, M; Nagashima, H; Nakatsukasa, H; Shiota, T; Watanabe, A; Yamauchi, Y | 1 |
Cronholm, T | 2 |
Brien, JF; Cameron, RJ; Loomis, CW; Steenaart, NA; Tam, GS | 1 |
Eriksson, CJ | 1 |
Annis, A; Peachey, JE | 1 |
Gessner, PK; Zaleska, MM | 1 |
Cappell, H; Jacob, M; Peachey, JE; Robinson, GM; Zilm, DH | 1 |
Dawson, AG | 1 |
Amit, Z; Brown, ZW; Selvaggi, N; Smith, BR; Sutherland, EA | 1 |
Heikkilä, J; Hillbom, M; Kupari, M; Lindros, K; Ylikahri, R | 1 |
Naranjo, CA; Peachey, JE | 1 |
DeMaster, EG; Nagasawa, HT; Shirota, FN | 2 |
Freundt, KJ; García de Torres, G; Römer, KG; Torres Alanis, O | 1 |
Hillbom, ME; Lindros, KO; Sarviharju, MS | 1 |
Brien, JF; Loomis, CW | 1 |
Cederbaum, AI; Dicker, E | 2 |
Weigand, K | 1 |
Lindros, KO; Stowell, A | 1 |
Cederbaum, AI | 1 |
Naranjo, CA; Peachey, JE; Sellers, EM | 1 |
Brien, JF; Loomis, CW; Peachey, JE; Roach, CA | 1 |
Peachey, JE; Sellers, EM | 1 |
Hillbom, M; Kupari, M; Lindros, K; Nieminen, M | 1 |
Hiltunen, AJ; Järbe, TU; Swedberg, MD | 1 |
Brien, JF; Hoover, DJ | 1 |
Lindros, KO; Sinclair, JD | 1 |
Deitrich, RA; Eriksson, CJ | 1 |
Aune, H; Mørland, J; Stowell, A | 1 |
Brien, JF; Hemy, MF; Loomis, CW; Maglana, SM; Peachey, JE; Zilm, DH | 1 |
Hillbom, ME; Larsen, A; Lindros, KO | 1 |
Brien, JF; Loomis, CW; Peachey, JE | 2 |
Lindros, KO; Sinclair, JD; Terho, K | 1 |
Brien, JF; Hemy, M; Maglana, S; Peachey, JE; Robinson, GM | 1 |
Marway, JS; Preedy, VR | 1 |
Griffiths, JR; Patel, VB; Preedy, VR; Richardson, PJ; Rodrigues, LM | 1 |
Ansell, H; Heap, LC; Patel, VB; Peters, TJ; Preedy, VR; Reilly, ME | 1 |
Riddle, MM; Smialowicz, RJ; Williams, WC | 1 |
Ameno, K; Ameno, S; Fuke, C; Ijiri, I; Shinohara, T | 1 |
Fillenwarth, MJ; Lin, RC; Lumeng, L; Zhou, FC | 1 |
Khan, S; O'Brien, PJ; Sood, C | 1 |
Adachi, J; Hishida, S; Ogawa, Y; Ouchi, H; Tatsuno, Y; Ueno, Y; Yamamoto, K | 1 |
Mitchell, WD; Preedy, VR; Richardson, PJ; Siddiq, T; Teare, J | 1 |
Ameno, K; Ameno, S; Fuke, C; Ijiri, I; Kinoshita, H | 1 |
Fujimiya, T; Komura, S; Li, YJ; Ohbora, Y; Uemura, K | 1 |
DeMaster, EG; Nagasawa, HT; Shirota, FN; Stevens-Johnk, JM | 1 |
Altomare, E; Grattagliano, I; Signorile, A; Vendemiale, G | 1 |
Altomare, E; Didonna, D; Gentile, A; Grattagliano, I; Vendemiale, G | 1 |
Fukuda, M; Horie, Y; Ishii, H; Kato, S; Nakamura, Y; Ohgo, H; Okamura, Y; Yokoyama, H | 1 |
Morris, JB; Stanek, JJ | 1 |
Blasco, C; Caballeria, J; Colell, A; Fernández-Checa, JC; Parés, A; Rodés, J; Román, J | 1 |
Crabb, DW; Dorris, R; Fischer, M; Galli, A; Pinaire, J | 1 |
Ameno, K; Coventry, TL; Finn, DP; Harbuz, MS; Ijiri, I; Jessop, DS; Kinoshita, H; Roberts, DJ | 1 |
Adachi, J; Asano, M; Camilleri, PM; Marway, JS; Peters, TJ; Preedy, VR; Ueno, Y | 1 |
Gianutsos, G; Morris, JB; Olsen, JE; Stanek, J; Symanowicz, PT | 1 |
Koll, M; Niemelä, O; Parkkila, S; Preedy, VR | 1 |
Aki, T; Fujimiya, T; Ohbora, Y; Shinagawa, H; Yamaoka, K | 1 |
De Witte, P; Escarabajal, MD; Quertemont, E | 1 |
Bonner, AB; Dalwai, S; Marway, JS; Preedy, VR | 1 |
Ameno, K; Ameno, S; Ijiri, I; Jamal, M; Okada, N | 2 |
FERGUSON, JK; WARSON, MD | 1 |
GRANT, GA; McCONKEY, HM; SKELTON, FR | 1 |
Hara, S; Higuchi, S; Ishii, H; Kato, S; Nakamura, Y; Yokoyama, H | 1 |
Ameno, K; Ameno, S; Ijiri, I; Jamal, M; Kubota, T; Kumihashi, M; Wang, W | 1 |
Ameno, K; Ameno, S; Ijiri, I; Ikuo, U; Jamal, M; Kumihashi, M; Shinji, A; Wang, W | 1 |
Didone, V; Quertemont, E; Tambour, S; Tirelli, E | 1 |
Broome, CS; Hirano, M; Hunter, R; Koll, M; Martin, CR; McArdle, A; Nakahara, T; Preedy, VR; Uchimura, H | 1 |
Colado, MI; Izco, M; O'Shea, E; Orio, L | 1 |
Benito Lozano, M; Lorenzo de la Peña, L; Martín Cabrera, F; Montero Santos, JM | 1 |
Ameno, K; Ijiri, I; Ikuo, U; Jamal, M; Kumihashi, M; Wang, W | 1 |
Ameno, K; Ijiri, I; Jamal, M; Kumihashi, M; Uekita, I; Wang, W | 1 |
Closon, C; Quertemont, E; Tambour, S; Tirelli, E | 1 |
Aung, CS; Cabot, PJ; Monteith, GR; Roberts-Thomson, SJ; Venkata, NG | 1 |
Israel, Y; Quintanilla, ME; Tampier, L | 1 |
Boyd, KN; Morrow, AL; O'Buckley, TK | 1 |
Gerland, B; Powner, MW; Sutherland, JD | 1 |
Closon, C; Didone, V; Quertemont, E; Tirelli, E | 1 |
Lindros, KO; Salaspuro, MP; Stowell, AR | 1 |
Abdel-Rahman, AA; El-Mas, MM | 1 |
Fujita, Y; Ikeda, C; Kawai, T; Kawashima, I; Mihara, T; Negishi, H; Richards, JS; Shimada, M | 1 |
Powner, MW; Szostak, JW; Zheng, SL | 1 |
Granero, L; Martí-Prats, L; Orrico, A; Polache, A; Sánchez-Catalán, MJ; Zornoza, T | 1 |
Lai, CL; Yao, CT; Yin, SJ | 1 |
Hashimoto, H; Hitomi, S; Inenaga, K; Kakinoki, Y; Ono, K; Ueta, Y; Ujihara, I | 1 |
Bartko, J; Boehm, T; Borth, N; Gludovacz, E; Jilma, B; Petroczi, K | 1 |
Amanuma, Y; Baba, K; Hirohashi, K; Ida, T; Kikuchi, O; Matsubara, J; Matsuda, T; Mitani, Y; Miyamoto, S; Mizumoto, A; Muto, M; Nakai, Y; Ohashi, S; Seno, H; Yamada, A; Yamamoto, Y | 1 |
6 review(s) available for acetaldehyde and cyanamide
Article | Year |
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Pharmacologic treatment of chronic alcoholism.
Topics: Acetaldehyde; Adrenergic beta-Antagonists; Alcoholics Anonymous; Alcoholism; Antidepressive Agents, Tricyclic; Anxiety Disorders; Benzodiazepines; Combined Modality Therapy; Cyanamide; Depressive Disorder; Disulfiram; Goals; Humans; Monoamine Oxidase Inhibitors; Psychoses, Substance-Induced; Recurrence | 1984 |
The role of drugs in the treatment of alcoholism.
Topics: Acetaldehyde; Alcoholism; Benzodiazepines; Cyanamide; Disulfiram; Drug Interactions; Humans; Mood Disorders; Substance-Related Disorders | 1984 |
[Advances in the field of alcohol-aversive agents].
Topics: Acetaldehyde; Alcohol Deterrents; Alcoholism; Cyanamide; Disulfiram; Humans; Nitroimidazoles | 1982 |
Drug therapy: Drugs to decrease alcohol consumption.
Topics: Acetaldehyde; Alcohol Deterrents; Alcohol Drinking; Alcoholism; Antidepressive Agents; Benzodiazepines; Cyanamide; Disulfiram; Humans; Kinetics; Lithium; Mental Disorders | 1981 |
A comparative review of the pharmacological and toxicological properties of disulfiram and calcium carbimide.
Topics: Acetaldehyde; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Cyanamide; Cyanides; Disulfiram; Drug Interactions; Ethanol; Humans; Intestinal Absorption | 1981 |
The disulfiram and calcium carbimide acetaldehyde-mediated ethanol reactions.
Topics: Acetaldehyde; Alcoholism; Aldehyde Oxidoreductases; Animals; Blood Pressure; Cyanamide; Cyanides; Disulfiram; Drug Interactions; Ethanol; Humans | 1981 |
5 trial(s) available for acetaldehyde and cyanamide
Article | Year |
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The calcium carbimide-ethanol interaction: effects of ethanol dose.
Topics: Acetaldehyde; Adult; Blood Pressure; Clinical Trials as Topic; Cyanamide; Cyanides; Dose-Response Relationship, Drug; Double-Blind Method; Ethanol; Heart Rate; Humans; Male; Placebos; Time Factors | 1979 |
Concentration-time profiles of ethanol and acetaldehyde in human volunteers treated with the alcohol-sensitizing drug, calcium carbimide.
Topics: Acetaldehyde; Adult; Breath Tests; Chromatography, Gas; Cyanamide; Cyanides; Ethanol; Humans; Male | 1988 |
Elimination kinetics of ethanol and acetaldehyde in healthy men during the calcium carbimide-alcohol flush reaction.
Topics: Acetaldehyde; Cyanamide; Cyanides; Ethanol; Flushing; Humans; Male | 1987 |
Diphenhydramine and the calcium carbimide-ethanol reaction: a placebo-controlled clinical study.
Topics: Acetaldehyde; Administration, Oral; Adult; Blood Pressure; Clinical Trials as Topic; Cyanamide; Cyanides; Diphenhydramine; Double-Blind Method; Drug Interactions; Ethanol; Female; Flushing; Humans; Infusions, Parenteral; Kinetics; Male; Pulse; Random Allocation | 1986 |
A placebo-controlled double-blind comparative clinical study of the disulfiram- and calcium carbimide-acetaldehyde mediated ethanol reactions in social drinkers.
Topics: Acetaldehyde; Adult; Alcoholism; Clinical Trials as Topic; Cyanamide; Cyanides; Disulfiram; Double-Blind Method; Ethanol; Humans; Male | 1983 |
120 other study(ies) available for acetaldehyde and cyanamide
Article | Year |
---|---|
Blood pressure response to ethanol in relation to acetaldehyde levels and dopamine-beta-hydroxylase activity in rats pretreated with disulfiram, cyanamide and coprine.
Topics: Acetaldehyde; Aldehyde Oxidoreductases; Animals; Blood Pressure; Brain; Cyanamide; Cyanides; Cyclopropanes; Disulfiram; Dopamine; Dopamine beta-Hydroxylase; Ethanol; Female; Glutamine; Myocardium; Norepinephrine; Rats | 1979 |
A comparative study on the effects of disulfiram, cyanamide and 1-aminocyclopropanol on the acetaldehyde metabolism in rats.
Topics: Acetaldehyde; Aldehyde Oxidoreductases; Animals; Cyanamide; Cyanides; Cyclopropanes; Cytosol; Disulfiram; Electrophoresis, Polyacrylamide Gel; Ethanol; Female; Liver; Microsomes, Liver; Mitochondria, Liver; Rats | 1978 |
A study of the calcium carbimide-ethanol interaction in man.
Topics: Acetaldehyde; Adult; Blood Pressure; Cyanamide; Cyanides; Drug Interactions; Ethanol; Heart Rate; Humans; Kinetics; Male | 1978 |
Inhibition of acetaminophen hepatotoxicity by acetaldehyde in the rat.
Topics: Acetaldehyde; Acetaminophen; Animals; Cyanamide; Drug Interactions; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley | 1992 |
Embryonic development in the chick following exposure to ethanol, acetaldehyde and cyanamide.
Topics: Acetaldehyde; Animals; Chick Embryo; Cyanamide; Drug Interactions; Embryonic and Fetal Development; Ethanol; Organ Size | 1992 |
The acute effects of ethanol and acetaldehyde on rates of protein synthesis in type I and type II fibre-rich skeletal muscles of the rat.
Topics: Acetaldehyde; Animals; Cyanamide; Ethanol; Fomepizole; Muscle Proteins; Muscles; Phenylalanine; Pyrazoles; Rats | 1992 |
Clinical responses in relation to blood acetaldehyde levels.
Topics: Acetaldehyde; Adult; Cyanamide; Disulfiram; Drug Interactions; Ethanol; Female; Humans; Male; Middle Aged | 1992 |
Ethanol metabolism in rat brain homogenates by a catalase-H2O2 system.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Amitrole; Animals; Brain Chemistry; Catalase; Cyanamide; Cytochrome P-450 Enzyme Inhibitors; Ethanol; Glucose Oxidase; Hydrogen Peroxide; Male; Metyrapone; Pyrazoles; Rats | 1992 |
Formation of the 37KD liver protein-acetaldehyde adduct in vivo and in vitro.
Topics: Acetaldehyde; Alcoholism; Aldehyde Dehydrogenase; Animals; Cells, Cultured; Chromatography, Affinity; Cyanamide; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Hemocyanins; Immunoblotting; Liver; Molecular Weight; Oxidoreductases, N-Demethylating; Proteins; Rats; Reference Values | 1991 |
Histochemical study of aldehyde dehydrogenase in the rat CNS.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Animals; Benzaldehydes; Biogenic Monoamines; Blood-Brain Barrier; Brain; Capillaries; Cyanamide; Disulfiram; Histocytochemistry; Male; Neurons; Rats; Spinal Cord; Tissue Distribution | 1991 |
Acetaldehyde increases procollagen type I and fibronectin gene transcription in cultured rat fat-storing cells through a protein synthesis-dependent mechanism.
Topics: Acetaldehyde; Animals; Cells, Cultured; Cyanamide; Cycloheximide; Fibronectins; Lipid Metabolism; Liver; Procollagen; Protein Biosynthesis; RNA, Messenger; Transcription, Genetic | 1991 |
Studies on ethanol-brain catalase interaction: evidence for central ethanol oxidation.
Topics: Acetaldehyde; Animals; Brain; Catalase; Cyanamide; Dose-Response Relationship, Drug; Ethanol; Male; Pyrazoles; Rats | 1991 |
Formation of a protein-acetaldehyde adduct in liver during chronic alcohol exposure.
Topics: Acetaldehyde; Alcoholism; Animals; Cyanamide; In Vitro Techniques; Liver; Male; Molecular Weight; Proteins; Pyrazoles; Rats; Rats, Inbred Strains | 1991 |
Evidence for nitroxyl in the catalase-mediated bioactivation of the alcohol deterrent agent cyanamide.
Topics: Acetaldehyde; Alcohol Deterrents; Aldehyde Dehydrogenase; Biotransformation; Catalase; Cyanamide; Humans; Magnetic Resonance Spectroscopy; Mitochondria, Liver; Nitrogen Oxides | 1990 |
Influence of aging on ethanol and acetaldehyde oxidation in female rat liver.
Topics: Acetaldehyde; Aging; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Aldehyde Dehydrogenase; Animals; Catalase; Cyanamide; Cytochrome P-450 Enzyme System; Cytosol; Ethanol; Female; Glutamate Dehydrogenase; Liver; Mitochondria, Liver; Oxidation-Reduction; Rats; Rats, Inbred F344 | 1990 |
Possible role of acetaldehyde in ethanol-related rectal cocarcinogenesis in the rat.
Topics: Acetaldehyde; Animals; Carcinogens; Cocarcinogenesis; Cyanamide; Dimethylnitrosamine; Ethanol; Intestinal Mucosa; Male; Rats; Rats, Inbred Strains; Rectal Neoplasms; Rectum | 1990 |
Formation of the 37-kD protein-acetaldehyde adduct in primary cultured rat hepatocytes exposed to alcohol.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Animals; Cells, Cultured; Culture Media; Cyanamide; Densitometry; Ethanol; Immunoblotting; Liver; Male; Microsomes, Liver; Oxidation-Reduction; Proteins; Rats; Rats, Inbred Strains | 1990 |
The roles of the hepatocellular redox state and the hepatic acetaldehyde concentration in determining the ethanol elimination rate in fasted rats.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Catechin; Cyanamide; Cysteine; Cytosol; Ethanol; Fasting; Kinetics; Liver; Male; Malonates; Mitochondria, Liver; NAD; Naloxone; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1985 |
Possible role of acetyl-CoA in the inhibition of CoA biosynthesis by ethanol in rats.
Topics: Acetaldehyde; Acetates; Acetyl Coenzyme A; Animals; Cells, Cultured; Coenzyme A; Cyanamide; Ditiocarb; Ethanol; Liver; Pantothenic Acid; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Rats | 1987 |
Role of acetaldehyde in ethanol-induced increase in the activity of phosphatidate phosphatase in rat liver.
Topics: Acetaldehyde; Administration, Oral; Animals; Cyanamide; Dactinomycin; Ethanol; Liver; Male; Paraldehyde; Phosphatidate Phosphatase; Phosphoric Monoester Hydrolases; Pyrazoles; Rats; Rats, Inbred Strains | 1987 |
Mitochondria as the primary site of acetaldehyde metabolism in beef and pig liver slices.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Animals; Cattle; Culture Techniques; Cyanamide; Disulfiram; Mitochondria, Liver; Swine | 1988 |
Induction of an allergic reaction to alcohol metabolites by immunization.
Topics: Acetaldehyde; Alcoholism; Aldehyde Dehydrogenase; Animals; Cyanamide; Disulfiram; Drug Hypersensitivity; Humans; Immunization; Male; Mice; Mice, Inbred C57BL; Rats | 1988 |
Depletion of hepatic glutathione by ethanol occurs independently of ethanol metabolism.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Cyanamide; Disulfiram; Ethanol; Female; Fomepizole; Glutathione; In Vitro Techniques; Liver; Male; Pyrazoles; Rats; Rats, Inbred Strains | 1988 |
Alterations in brain aldehyde dehydrogenase activity modify ethanol-induced conditioned taste aversion.
Topics: Acetaldehyde; Animals; Conditioning, Psychological; Cyanamide; Ethanol; Fomepizole; Male; Pyrazoles; Rats; Saccharin; Taste | 1987 |
Mechanisms of fetal alcohol effects: role of acetaldehyde.
Topics: Acetaldehyde; Animals; Cyanamide; Embryo Loss; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Pregnancy; Random Allocation; Rats; Rats, Inbred Strains; Teratogens | 1988 |
Rate determining factors of ethanol oxidation in hepatocytes from starved and fed rats: effect of acetaldehyde concentration on the rate of NADH oxidation catalyzed by alcohol dehydrogenase.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Animals; Cyanamide; Ethanol; Female; Fructose; L-Lactate Dehydrogenase; Liver; NAD; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1987 |
The role of acetaldehyde-metabolizing enzymes in the mediation of ethanol consumption: an investigation using a simulated drinking bout.
Topics: Acetaldehyde; Alcohol Drinking; Aldehyde Dehydrogenase; Animals; Cyanamide; Fomepizole; Male; Pyrazoles; Rats | 1987 |
Blood acetaldehyde and the ethanol-induced increase in splanchnic circulation.
Topics: Acetaldehyde; Administration, Oral; Animals; Cardiac Output; Cyanamide; Ethanol; Male; Rats; Rats, Inbred Strains; Regional Blood Flow; Splanchnic Circulation | 1987 |
Metabolic basis of ethylene glycol monobutyl ether (2-butoxyethanol) toxicity: role of alcohol and aldehyde dehydrogenases.
Topics: Acetaldehyde; Acetates; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Biotransformation; Cyanamide; Deuterium; Ethylene Glycols; Glucuronates; Glycolates; Hematologic Diseases; Male; Pyrazoles; Rats; Rats, Inbred F344; Sulfates | 1987 |
Beta-substituted cysteines as sequestering agents for ethanol-derived acetaldehyde in vivo.
Topics: Acetaldehyde; Animals; Chemical Phenomena; Chemistry; Cyanamide; Cysteine; Disulfiram; Ethanol; Male; Oxidation-Reduction; Penicillamine; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1987 |
Effects of a small dose of ethanol and calcium carbimide-induced acetaldehyde intoxication on human platelet aggregation, associated thromboxane formation and urinary excretion of 2,3-dinor-6-keto prostaglandin F1 alpha.
Topics: 6-Ketoprostaglandin F1 alpha; Acetaldehyde; Adult; Blood Pressure; Cyanamide; Cyanides; Ethanol; Humans; Lipid Peroxides; Male; Platelet Aggregation; Thromboxane B2 | 1987 |
Alterations in brain aldehyde dehydrogenase activity modify the locomotor effects produced by ethanol in rats.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Brain; Cyanamide; Ethanol; Fomepizole; Male; Motor Activity; Pyrazoles; Rats | 1987 |
Evidence for the generation of transaminase inhibitor(s) during ethanol metabolism by rat liver homogenates: a potential mechanism for alcohol toxicity.
Topics: Acetaldehyde; Alanine Transaminase; Animals; Aspartate Aminotransferases; Cyanamide; Cytosol; Ethanol; Kinetics; Liver; Rats; Rats, Inbred Strains; Semicarbazides; Sodium Cyanide; Sorbitol | 1987 |
[Calcium carbimide together with light wine as the cause of heart infarction].
Topics: Acetaldehyde; Adult; Cyanamide; Cyanides; Drug Interactions; Ethanol; Humans; Male; Myocardial Infarction; Wine | 1986 |
Aldehyde dehydrogenase activity as the rate-limiting factor for acetaldehyde metabolism in rat liver.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Animals; Cyanamide; Electron Transport; Ethanol; In Vitro Techniques; Kinetics; Liver; Male; Mitochondria, Liver; NAD; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1985 |
Covalent binding of acetaldehyde to hepatic proteins during ethanol oxidation.
Topics: Acetaldehyde; Animals; Cyanamide; Cycloheximide; Ethanol; In Vitro Techniques; Liver; Male; Oxidation-Reduction; Proteins; Puromycin; Pyrazoles; Rats; Rats, Inbred Strains | 1985 |
Demonstration of a functional blood-testis barrier to acetaldehyde. Evidence for lack of acetaldehyde effect on ethanol-induced depression of testosterone in vivo.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Animals; Chorionic Gonadotropin; Cyanamide; Ethanol; Fomepizole; Male; Mice; Pargyline; Pyrazoles; Testis; Testosterone | 1985 |
Effects of high hepatic acetaldehyde level following simultaneous administration of ethanol and cyanamide on liver function in rats.
Topics: Acetaldehyde; Alanine Transaminase; Animals; Aspartate Aminotransferases; Bilirubin; Cyanamide; Cyanides; Ethanol; Hydroxyproline; Liver; Liver Function Tests; Male; Rats; Rats, Inbred Strains; Triglycerides | 1985 |
Hydrogen transfer between ethanol molecules during oxidoreduction in vivo.
Topics: Acetaldehyde; Animals; Bile; Cyanamide; Deuterium; Ethanol; Female; Hydrogen; NAD; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1985 |
A comparative study of the inhibition of hepatic aldehyde dehydrogenases in the rat by methyltetrazolethiol, calcium carbimide, and disulfiram.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Animals; Azoles; Cyanamide; Cyanides; Disulfiram; Ethanol; Injections, Intravenous; Kinetics; Liver; Male; Rats; Rats, Inbred Strains; Tetrazoles; Time Factors | 1985 |
Endogenous acetaldehyde in rats. Effects of exogenous ethanol, pyrazole, cyanamide and disulfiram.
Topics: Acetaldehyde; Animals; Cyanamide; Cyanides; Disulfiram; Eating; Ethanol; Male; Pyrazoles; Rats | 1985 |
Metabolism of [14C]paraldehyde in mice in vivo, generation and trapping of acetaldehyde.
Topics: Acetaldehyde; Animals; Biotransformation; Breath Tests; Cyanamide; Ditiocarb; Kinetics; Male; Mice; Mice, Inbred BALB C; Models, Biological; Paraldehyde; Pargyline; Proadifen | 1983 |
Ethanol oxidation in systems containing soluble and mitochondrial fractions of rat liver. Regulation by acetaldehyde.
Topics: Acetaldehyde; Acetates; Alcohol Oxidoreductases; Aldehyde Oxidoreductases; Animals; Cyanamide; Ethanol; Female; Kinetics; Mitochondria, Liver; NAD; Oxidation-Reduction; Pyruvates; Rats; Rats, Inbred Strains | 1983 |
Alcohol-induced euphoria enhanced by disulfiram and calcium carbimide.
Topics: Acetaldehyde; Adult; Cyanamide; Cyanides; Disulfiram; Double-Blind Method; Drug Synergism; Ethanol; Euphoria; Humans; Male | 1983 |
Cardiovascular effects of acetaldehyde accumulation after ethanol ingestion: their modification by beta-adrenergic blockade and alcohol dehydrogenase inhibition.
Topics: Acetaldehyde; Adult; Alcohol Dehydrogenase; Alcohol Drinking; Alcohol Oxidoreductases; Alcoholic Intoxication; Blood Pressure; Cardiac Output; Cyanamide; Cyanides; Echocardiography; Ethanol; Fomepizole; Heart Rate; Hemodynamics; Humans; Male; Propranolol; Pyrazoles | 1983 |
The metabolic activation of cyanamide to an inhibitor of aldehyde dehydrogenase is catalyzed by catalase.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Amitrole; Animals; Biotransformation; Catalase; Catalysis; Cattle; Cyanamide; Cyanides; Male; Mitochondria, Liver; Rats; Rats, Inbred Strains; Saccharomyces cerevisiae | 1984 |
Blood acetaldehyde levels in alcohol-dosed rats after treatment with ANIT, ANTU, dithiocarbamate derivatives, or cyanamide.
Topics: 1-Naphthylisothiocyanate; Acetaldehyde; Animals; Cyanamide; Cyanides; Drug Interactions; Ethanol; Female; Rats; Rats, Inbred Strains; Thiocarbamates; Thiocyanates; Thiourea; Thiram; Zineb; Ziram | 1983 |
Potentiation of ethanol toxicity by cyanamide in relation to acetaldehyde accumulation.
Topics: Acetaldehyde; Animals; Cyanamide; Cyanides; Drug Synergism; Ethanol; Fomepizole; Lethal Dose 50; Male; Pyrazoles; Rats | 1983 |
Metabolic activation of cyanamide to an inhibitor of aldehyde dehydrogenase in vitro.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Animals; Biotransformation; Cyanamide; Cyanides; Cytosol; Ethanol; Isoenzymes; Kinetics; Male; Microsomes, Liver; Mitochondria, Liver; Rats; Rats, Inbred Strains | 1983 |
Decrease in calcium carbimide (calcium cyanamide)-induced inhibition of rat hepatic aldehyde dehydrogenases by multiple ethanol administration.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Animals; Cyanamide; Cyanides; Dose-Response Relationship, Drug; Ethanol; Kinetics; Liver; Male; Rats; Rats, Inbred Strains | 1984 |
Effect of acetaldehyde and cyanamide on the metabolism of formaldehyde by hepatocytes, mitochondria, and soluble supernatant from rat liver.
Topics: Acetaldehyde; Animals; Cyanamide; Cyanides; Formaldehyde; In Vitro Techniques; Liver; Male; Mitochondria, Liver; Oxidation-Reduction; Rats; Rats, Inbred Strains; Subcellular Fractions | 1984 |
Effects of ethanol-derived acetaldehyde on the phosphorylation potential and on the intramitochondrial redox state in intact rat liver.
Topics: Acetaldehyde; Adenine Nucleotides; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Cyanamide; Ethanol; Kinetics; L-Lactate Dehydrogenase; Male; Mitochondria, Liver; NAD; Oxidation-Reduction; Phosphorylation; Rats | 1982 |
The effect of cyanamide on acetaldehyde oxidation by isolated rat liver mitochondria and on the inhibition of pyruvate oxidation by acetaldehyde.
Topics: Acetaldehyde; Aldehyde Oxidoreductases; Animals; Cyanamide; Cyanides; In Vitro Techniques; Male; Mitochondria, Liver; Oxidation-Reduction; Oxygen Consumption; Pyruvates; Rats | 1981 |
Possible cardiovascular hazards of the alcohol-calcium carbimide interaction.
Topics: Acetaldehyde; Adult; Breath Tests; Chromatography, Gas; Cyanamide; Cyanides; Drug Interactions; Electrocardiography; Ethanol; Hemodynamics; Humans; Male | 1982 |
Ethanol as a discriminative stimulus: effects of cyanamide, acetaldehyde and chlormethiazole.
Topics: Acetaldehyde; Animals; Chlormethiazole; Cyanamide; Cyanides; Discrimination Learning; Ethanol; Female; Gerbillinae; Male; Motor Activity; Reaction Time | 1982 |
Acetaldehyde concentration in rat blood and brain during the calcium carbimide--ethanol interaction.
Topics: Acetaldehyde; Animals; Brain; Cyanamide; Cyanides; Drug Interactions; Ethanol; Male; Rats; Time Factors | 1981 |
Suppression of alcohol drinking with brain aldehyde dehydrogenase inhibition.
Topics: Acetaldehyde; Alcohol Drinking; Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Animals; Brain; Cyanamide; Drug Interactions; Fomepizole; Male; Pyrazoles; Rats; Time Factors | 1981 |
Evidence against a biphasic effect of acetaldehyde on voluntary ethanol consumption in rats.
Topics: Acetaldehyde; Alcohol Drinking; Animals; Cyanamide; Male; Rats; Time Factors | 1980 |
Production of acetaldehyde and ethanol by isolated rat liver parenchymal cells in the presence of diethyl ether.
Topics: Acetaldehyde; Animals; Cells, Cultured; Cyanamide; Enzyme Inhibitors; Ethanol; Ether; Ethyl Ethers; Liver; Male; Phenobarbital; Rats | 1981 |
The calcium cyanamide--ethanol interaction in man. Effects of repeated ethanol administration.
Topics: Acetaldehyde; Adult; Blood Pressure; Body Temperature; Cyanamide; Cyanides; Drug Interactions; Ethanol; Heart Rate; Humans; Male; Middle Aged | 1981 |
The calcium carbimide-ethanol interaction: lack of relation between electroencephalographic response and cerebrospinal fluid acetaldehyde.
Topics: Acetaldehyde; Adult; Brain; Cyanamide; Cyanides; Drug Interactions; Electroencephalography; Ethanol; Humans; Intestinal Absorption; Male | 1981 |
Effect of cyanamide on the metabolism of ethanol and acetaldehyde and on gluconeogenesis by isolated rat hepatocytes.
Topics: Acetaldehyde; Animals; Cyanamide; Cyanides; Ethanol; Gluconeogenesis; In Vitro Techniques; Liver; Male; NAD; Oxidation-Reduction; Pyrazoles; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Sorbitol; Xylitol | 1981 |
Calcium carbimide--ethanol interaction.
Topics: Acetaldehyde; Adult; Alcoholism; Cyanamide; Cyanides; Drug Interactions; Ethanol; Heart Rate; Humans; Male; Middle Aged; Time Factors | 1980 |
Aldehyde dehydrogenase inhibitors and voluntary ethanol drinking by rats.
Topics: Acetaldehyde; Alcohol Drinking; Aldehyde Oxidoreductases; Animals; Cyanamide; Cyclopropanes; Drug Tolerance; Ethanol; Glutamine; Postural Balance; Rats | 1980 |
Intraindividual variability in the calcium carbimide-ethanol interaction.
Topics: Acetaldehyde; Adult; Alcoholism; Aldehyde Oxidoreductases; Cyanamide; Cyanides; Drug Interactions; Ethanol; Heart Rate; Humans; Individuality; Male; Middle Aged; Time Factors | 1980 |
Cardiovascular changes during the calcium carbimide-ethanol interaction.
Topics: Acetaldehyde; Adult; Alcoholism; Cardiovascular System; Cyanamide; Cyanides; Disulfiram; Ethanol; Humans; Hypotension; Male; Middle Aged | 1981 |
The acute effects of ethanol and acetaldehyde on the synthesis of mixed and contractile proteins of the jejunum.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcoholic Intoxication; Aldehyde Dehydrogenase; Animals; Contractile Proteins; Cyanamide; Ethanol; Fomepizole; Gastrointestinal Motility; Jejunum; Male; Muscle Proteins; Muscle, Smooth; Pyrazoles; Rats; Rats, Wistar | 1995 |
The acute effects of alcohol and acetaldehyde on cardiac nucleotide levels.
Topics: Acetaldehyde; Adenine Nucleotides; Analysis of Variance; Animals; Cyanamide; Ethanol; Guanine Nucleotides; Heart; Myocardium; Rats; Reference Values | 1994 |
Antioxidant status in skeletal muscle and plasma of rats treated with ethanol.
Topics: Acetaldehyde; Alcoholism; Animals; Antioxidants; Cyanamide; Ethanol; Male; Rats; Rats, Wistar; Vitamin A; Vitamin E | 1994 |
Methoxyacetaldehyde, an intermediate metabolite of 2-methoxyethanol, is immunosuppressive in the rat.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Animals; Antibody Formation; Cyanamide; Disulfiram; Ethylene Glycols; Fomepizole; Immune Tolerance; Lipopolysaccharides; Male; Pyrazoles; Rats; Rats, Inbred F344; Solvents | 1993 |
A comparative study of ethanol absorption in the canine jejunum after pretreatment with cyanamide or pyrazole.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Animals; Cyanamide; Dogs; Ethanol; Intestinal Absorption; Jejunum; Male; Pyrazoles | 1993 |
Zonal distribution of protein-acetaldehyde adducts in the liver of rats fed alcohol for long periods.
Topics: Acetaldehyde; Alcoholism; Animals; Cyanamide; Ethanol; Immunohistochemistry; Liver; Male; Proteins; Rats; Rats, Wistar; Time Factors | 1993 |
Molecular mechanisms of dibromoalkane cytotoxicity in isolated rat hepatocytes.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Animals; Cyanamide; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Disulfiram; Ethanol; Ethylene Dibromide; Glutathione; Hydrocarbons, Brominated; Lipid Peroxidation; Liver; Male; Microsomes, Liver; Models, Biological; Protein Binding; Rats; Rats, Sprague-Dawley | 1993 |
Ethanol metabolism in isolated hepatocytes. Effects of methylene blue, cyanamide and penicillamine on the redox state of the bound coenzyme and on the substrate exchange at alcohol dehydrogenase.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Animals; Cyanamide; Ethanol; Female; In Vitro Techniques; Liver; Methylene Blue; NAD; Oxidation-Reduction; Penicillamine; Rats; Rats, Sprague-Dawley | 1993 |
Acetaldehyde-induced formation of 1-methyl-1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid in rats.
Topics: Acetaldehyde; Animals; Carbolines; Cyanamide; Diet; Ethanol; Fasting; Male; Rats; Rats, Wistar; Tryptophan | 1993 |
Ethanol-induced inhibition of ventricular protein synthesis in vivo and the possible role of acetaldehyde.
Topics: Acetaldehyde; Animals; Cardiomyopathy, Alcoholic; Cyanamide; Depression, Chemical; Ethanol; Fomepizole; Heart Ventricles; Male; Muscle Proteins; Protein Synthesis Inhibitors; Pyrazoles; Rats; Rats, Wistar | 1993 |
Additional proof of reduction of ethanol absorption from rat intestine in vivo by high acetaldehyde concentrations.
Topics: Acetaldehyde; Animals; Cyanamide; Ethanol; Fomepizole; Intestinal Absorption; Pyrazoles; Rats; Rats, Wistar | 1995 |
Noncompetitive-like inhibition of ethanol elimination by cyanamide treatment: pharmacokinetic study.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Animals; Cyanamide; Dose-Response Relationship, Drug; Ethanol; Infusions, Intravenous; Injections, Intraperitoneal; Male; Metabolic Clearance Rate; Rabbits | 1996 |
Novel prodrugs of cyanamide that inhibit aldehyde dehydrogenase in vivo.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Animals; Catalase; Cyanamide; Enzyme Inhibitors; Ethanol; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Prodrugs; Rats; Rats, Sprague-Dawley; Thiourea | 1997 |
Ethanol-induced changes of intracellular thiol compartmentation and protein redox status in the rat liver: effect of tauroursodeoxycholate.
Topics: Acetaldehyde; Alcohol Drinking; Animals; Cell Nucleus; Cyanamide; Cytosol; Ethanol; Fomepizole; Glutathione; Kinetics; Liver; Male; Malondialdehyde; Mitochondria, Liver; Oxidation-Reduction; Proteins; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Taurochenodeoxycholic Acid | 1998 |
Gastric and intestinal ethanol toxicity in the rat. Effect on glutathione level and role of alcohol and acetaldehyde metabolisms.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Anti-Ulcer Agents; Cimetidine; Cyanamide; Dose-Response Relationship, Drug; Ethanol; Follow-Up Studies; Gastric Mucosa; Glutathione; Intestinal Mucosa; Male; Maleates; Rats; Rats, Sprague-Dawley; Time Factors | 1998 |
Evidence for ethanol oxidation by Kupffer cells.
Topics: Acetaldehyde; Acetates; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Carbon Radioisotopes; Cyanamide; Disulfiram; Enzyme Inhibitors; Ethanol; Kupffer Cells; Male; Oxidation-Reduction; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 1999 |
The effect of inhibition of aldehyde dehydrogenase on nasal uptake of inspired acetaldehyde.
Topics: Acetaldehyde; Administration, Inhalation; Aldehyde Dehydrogenase; Animals; Carcinogens; Cross-Linking Reagents; Cyanamide; DNA; Dose-Response Relationship, Drug; Nasal Mucosa; Nose; Proteins; Rats; Rats, Inbred F344; Specific Pathogen-Free Organisms; Time Factors | 1999 |
Differential role of ethanol and acetaldehyde in the induction of oxidative stress in HEP G2 cells: effect on transcription factors AP-1 and NF-kappaB.
Topics: Acetaldehyde; Antioxidants; Binding, Competitive; Buthionine Sulfoximine; Cyanamide; Cytochrome P-450 CYP2E1; DNA; Ethanol; Gene Expression Regulation; Glutathione; Humans; Liver; NF-kappa B; Oxidative Stress; Peroxides; Reactive Oxygen Species; Transcription Factor AP-1; Transfection; Tumor Cells, Cultured | 1999 |
The transcriptional and DNA binding activity of peroxisome proliferator-activated receptor alpha is inhibited by ethanol metabolism. A novel mechanism for the development of ethanol-induced fatty liver.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Cells, Cultured; Cyanamide; DNA; DNA-Binding Proteins; Ethanol; Fomepizole; Genes, Reporter; Liver; Male; Nuclear Proteins; Protein Binding; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 2001 |
Acute ethanol decreases NPY mRNA but not POMC mRNA in the arcuate nucleus.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Animals; Arcuate Nucleus of Hypothalamus; Cyanamide; Ethanol; Gene Expression Regulation; Male; Neuropeptide Y; Pro-Opiomelanocortin; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription, Genetic | 2000 |
Acute effect of ethanol on 7-hydroperoxycholesterol in muscle and liver.
Topics: Acetaldehyde; Animals; Cholesterol; Cyanamide; Drug Interactions; Ethanol; Liver; Male; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Rats; Rats, Wistar | 2001 |
Sensory-nerve-mediated nasal vasodilatory response to inspired acetaldehyde and acetic acid vapors.
Topics: Acetaldehyde; Acetic Acid; Administration, Inhalation; Airway Resistance; Aldehyde Dehydrogenase; Animals; Cyanamide; Enzyme Inhibitors; Male; Nasal Cavity; Nasal Mucosa; Nasal Septum; Neurons, Afferent; Plethysmography; Rats; Rats, Inbred F344; Vasodilation; Volatilization | 2001 |
Generation of protein adducts with malondialdehyde and acetaldehyde in muscles with predominantly type I or type II fibers in rats exposed to ethanol and the acetaldehyde dehydrogenase inhibitor cyanamide.
Topics: Acetaldehyde; Aldehyde Oxidoreductases; Animals; Cyanamide; Drug Synergism; Enzyme Inhibitors; Ethanol; Immunohistochemistry; Liver; Male; Malondialdehyde; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Muscle Proteins; Muscle, Skeletal; Rats; Rats, Wistar | 2002 |
Michaelis-Menten elimination kinetics of acetaldehyde during ethanol oxidation.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Cyanamide; Ethanol; Metabolic Clearance Rate; Oxidation-Reduction; Rabbits | 2002 |
Role of acetaldehyde in ethanol-induced conditioned taste aversion in rats.
Topics: Acetaldehyde; Alcohol Deterrents; Alcohol Drinking; Animals; Behavior, Animal; Choice Behavior; Conditioning, Psychological; Cyanamide; Dose-Response Relationship, Drug; Drinking Behavior; Ethanol; Male; Rats; Rats, Wistar; Saccharin; Sodium Chloride; Water | 2003 |
Acute exposure to the nutritional toxin alcohol reduces brain protein synthesis in vivo.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Animals; Brain Chemistry; Central Nervous System Depressants; Cyanamide; Drug Tolerance; Enzyme Inhibitors; Ethanol; Kinetics; Male; Nerve Tissue Proteins; Phenylalanine; Rats; Rats, Wistar | 2003 |
Effect of different doses of cyanamide on striatal salsolinol formation after ethanol treatment.
Topics: Acetaldehyde; Animals; Central Nervous System Depressants; Chromatography, High Pressure Liquid; Corpus Striatum; Cyanamide; Dose-Response Relationship, Drug; Ethanol; Infusions, Parenteral; Isoquinolines; Male; Microdialysis; Rats; Rats, Wistar | 2003 |
In vivo study of salsolinol produced by a high concentration of acetaldehyde in the striatum and nucleus accumbens of free-moving rats.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Cyanamide; Dopamine; Dose-Response Relationship, Drug; Ethanol; Fomepizole; Isoquinolines; Male; Microdialysis; Nucleus Accumbens; Pyrazoles; Rats; Rats, Wistar; Serotonin | 2003 |
Effects of cyanamide and ethanol of bleeding weight and blood acetaldehyde in mice and rats.
Topics: Acetaldehyde; Amides; Animals; Blood; Body Weight; Body Weights and Measures; Cyanamide; Cyanides; Ethanol; Mice; Rats | 1955 |
Synergistic action of antabuse and intravenous cyanamide on blood acetaldehyde following alcohol administration.
Topics: Acetaldehyde; Cyanamide; Disulfiram; Ethanol; Humans; Urea | 1952 |
Acetaldehyde accumulation suppresses Kupffer cell release of TNF-Alpha and modifies acute hepatic inflammation in rats.
Topics: Acetaldehyde; Animals; Blotting, Northern; Cell Culture Techniques; Chemical and Drug Induced Liver Injury; Cyanamide; Disulfiram; Ethanol; Kupffer Cells; Lipopolysaccharides; Liver; Male; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2004 |
Failure of ethanol and acetaldehyde to alter in vivo norepinephrine release in the striatum and hippocampus of rats.
Topics: Acetaldehyde; Animals; Central Nervous System Depressants; Chromatography, High Pressure Liquid; Corpus Striatum; Cyanamide; Drug Synergism; Ethanol; Hippocampus; Injections, Intraperitoneal; Male; Microdialysis; Norepinephrine; Rats; Rats, Wistar | 2004 |
Inhibition of acetaldehyde metabolism decreases acetylcholine release in medial frontal cortex of freely moving rats.
Topics: Acetaldehyde; Acetylcholine; Analysis of Variance; Animals; Cyanamide; Ethanol; Frontal Lobe; Male; Microdialysis; Rats; Rats, Wistar | 2005 |
Dissociation between the locomotor and anxiolytic effects of acetaldehyde in the elevated plus-maze: evidence that acetaldehyde is not involved in the anxiolytic effects of ethanol in mice.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Animals; Anti-Anxiety Agents; Central Nervous System Depressants; Cyanamide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanol; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Motor Activity; Species Specificity | 2005 |
Alcohol alters skeletal muscle heat shock protein gene expression in rats: these effects are moderated by sex, raised endogenous acetaldehyde, and starvation.
Topics: Acetaldehyde; Animals; Cyanamide; Ethanol; Female; Gene Expression; Heat-Shock Proteins; Male; Muscle, Skeletal; Rats; Rats, Wistar; RNA, Messenger; Sex Factors; Starvation | 2006 |
Binge ethanol administration enhances the MDMA-induced long-term 5-HT neurotoxicity in rat brain.
Topics: Acetaldehyde; Alcoholic Intoxication; Aldehyde Dehydrogenase; Animals; Body Temperature; Brain; Central Nervous System Depressants; Cyanamide; Drug Interactions; Enzyme Inhibitors; Ethanol; Fever; Hot Temperature; Hydroxyl Radical; Inhalation Exposure; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Rats; Serotonin; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins; Serotonin Syndrome; Time Factors | 2007 |
[Acetaldehyde syndrome after laboral exposition to hydrogen cyanamide].
Topics: Acetaldehyde; Alcohol Deterrents; Cyanamide; Ethanol; Humans; Male; Middle Aged; Occupational Exposure; Pesticides; Treatment Outcome | 2006 |
Ethanol and acetaldehyde: in vivo quantitation and effects on cholinergic function in rat brain.
Topics: Acetaldehyde; Alcohol Drinking; Animals; Blotting, Western; Brain; Catalase; Choline O-Acetyltransferase; Cyanamide; Ethanol; Fomepizole; Male; Microdialysis; Pyrazoles; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction | 2007 |
Catalase mediates acetaldehyde formation in the striatum of free-moving rats.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Amitrole; Animals; Basal Ganglia; Catalase; Chromatography, Gas; Cyanamide; Enzyme Inhibitors; Ethanol; Fomepizole; Locomotion; Male; Microdialysis; Oxidation-Reduction; Pyrazoles; Rats; Rats, Wistar; Sodium Azide; Time Factors | 2007 |
Effects of cyanamide and acetaldehyde accumulation on the locomotor stimulant and sedative effects of ethanol in mice.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Animals; Brain; Cyanamide; Dose-Response Relationship, Drug; Ethanol; Fomepizole; Hypnotics and Sedatives; Male; Mice; Motor Activity; Pyrazoles; Reflex | 2007 |
PPARalpha and PPARbeta are differentially affected by ethanol and the ethanol metabolite acetaldehyde in the MCF-7 breast cancer cell line.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Aldehyde Oxidoreductases; Breast Neoplasms; Cell Line, Tumor; Cyanamide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanol; Female; Fomepizole; Gene Expression Regulation, Neoplastic; Humans; PPAR alpha; PPAR-beta; Pyrazoles; RNA, Messenger; Thiazoles; Transcription, Genetic; Transcriptional Activation; Transfection | 2008 |
Tolerance to disulfiram induced by chronic alcohol intake in the rat.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Deterrents; Alcohol Drinking; Alcoholism; Animals; Cyanamide; Disulfiram; Drug Tolerance; Enzyme Inhibitors; Ethanol; Female; Rats; Rats, Wistar | 2008 |
Role of acetaldehyde in ethanol-induced elevation of the neuroactive steroid 3alpha-hydroxy-5alpha-pregnan-20-one in rats.
Topics: Acetaldehyde; Animals; Cerebral Cortex; Cyanamide; Ethanol; Male; Pregnanolone; Rats; Rats, Sprague-Dawley | 2008 |
Synthesis of activated pyrimidine ribonucleotides in prebiotically plausible conditions.
Topics: Acetaldehyde; Acetylene; Arabinose; Buffers; Catalysis; Cyanamide; Glyceraldehyde; Hydrogen-Ion Concentration; Models, Chemical; Nitriles; Origin of Life; Oxazoles; Phosphates; Phosphorylation; Pyrimidines; Ribonucleotides; Ribose | 2009 |
Acetaldehyde and the hypothermic effects of ethanol in mice.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Animals; Body Temperature; Central Nervous System Depressants; Cyanamide; Drug Synergism; Enzyme Inhibitors; Ethanol; Female; Fomepizole; Hypothermia; Liver; Mice; Pyrazoles | 2009 |
Breath and blood acetaldehyde concentrations and their correlation during normal and calcium carbimide-modified ethanol oxidation in man.
Topics: Acetaldehyde; Adult; Breath Tests; Cyanamide; Ethanol; Humans; Kinetics; Male; Oxidation-Reduction | 1980 |
Enhanced catabolism to acetaldehyde in rostral ventrolateral medullary neurons accounts for the pressor effect of ethanol in spontaneously hypertensive rats.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Animals; Autonomic Pathways; Blood Pressure; Catalase; Central Nervous System Depressants; Cyanamide; Ethanol; Hypertension; Male; Medulla Oblongata; Metabolism; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reticular Formation; Species Specificity | 2012 |
Endogenous acetaldehyde toxicity during antral follicular development in the mouse ovary.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Animals; Chorionic Gonadotropin; Cyanamide; Disulfiram; Enzyme Inhibitors; Female; Mice; Mice, Inbred C57BL; Ovarian Follicle | 2012 |
Multicomponent assembly of proposed DNA precursors in water.
Topics: Acetaldehyde; Cyanamide; Deoxyribonucleotides; DNA; Oxazoles; Thiazoles; Thiosugars; Water | 2012 |
Opposite motor responses elicited by ethanol in the posterior VTA: the role of acetaldehyde and the non-metabolized fraction of ethanol.
Topics: Acetaldehyde; Animals; Bicuculline; Central Nervous System Depressants; Cyanamide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanol; GABA-A Receptor Antagonists; Male; Microinjections; Motor Activity; Rats; Rats, Wistar; Ventral Tegmental Area | 2013 |
Steady-state metabolism of ethanol in perfused rat livers treated with cyanamide: quantitative analysis of acetaldehyde effects on the metabolic flux rates.
Topics: Acetaldehyde; Acetates; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Cyanamide; Dose-Response Relationship, Drug; Ethanol; Kinetics; Liver; Male; Mitochondria; Oxidation-Reduction; Perfusion; Rats | 2015 |
The ethanol metabolite acetaldehyde induces water and salt intake via two distinct pathways in the central nervous system of rats.
Topics: Acetaldehyde; Alcohol Drinking; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Central Nervous System Agents; Circumventricular Organs; Cyanamide; Diuresis; Drinking; Ethanol; Green Fluorescent Proteins; Male; Neurons; Proto-Oncogene Proteins c-fos; Rats, Transgenic; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin; Sodium Chloride, Dietary; Thirst | 2015 |
Recombinant human diamine oxidase activity is not inhibited by ethanol, acetaldehyde, disulfiram, diethyldithiocarbamate or cyanamide.
Topics: Acetaldehyde; Amine Oxidase (Copper-Containing); Animals; Cells, Cultured; Cricetulus; Cyanamide; Disulfiram; Ditiocarb; Enzyme Inhibitors; Ethanol; Humans; Recombinant Proteins | 2016 |
Protective effects of Alda-1, an ALDH2 activator, on alcohol-derived DNA damage in the esophagus of human ALDH2*2 (Glu504Lys) knock-in mice.
Topics: Acetaldehyde; Alcohol Drinking; Aldehyde Dehydrogenase, Mitochondrial; Animals; Benzamides; Benzodioxoles; Carcinogenesis; Cyanamide; DNA Adducts; DNA Damage; Esophageal Mucosa; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Ethanol; Gene Knock-In Techniques; Humans; Male; Mice, Transgenic; Mutation; Neoplasms, Experimental; Polymorphism, Genetic; Risk Factors | 2020 |