acecainide and hydralazine

acecainide has been researched along with hydralazine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's2 (25.00)18.2507
2000's3 (37.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Koopman, WJ; Zacharias, W1
Cornacchia, E; Golbus, J; Hanash, S; Maybaum, J; Richardson, B; Strahler, J1
Reidenberg, MM1
Ayer, LM; Edworthy, SM; Fritzler, MJ1

Other Studies

8 other study(ies) available for acecainide and hydralazine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Lupus-inducing drugs alter the structure of supercoiled circular DNA domains.
    Arthritis and rheumatism, 1990, Volume: 33, Issue:3

    Topics: Acecainide; Animals; Antibodies; Canavanine; DNA, Superhelical; Electrophoresis, Agar Gel; Escherichia coli; Hydralazine; Lupus Erythematosus, Systemic; Plasmids; Procainamide

1990
N-acetylprocainamide is a less potent inducer of T cell autoreactivity than procainamide.
    Arthritis and rheumatism, 1988, Volume: 31, Issue:8

    Topics: Acecainide; Autoantibodies; Autoimmune Diseases; Chromatography, High Pressure Liquid; DNA; Humans; Hydralazine; In Vitro Techniques; Methylation; Phthalazines; Procainamide; T-Lymphocytes

1988
The chemical induction of systemic lupus erythematosus and lupus-like illnesses.
    Arthritis and rheumatism, 1981, Volume: 24, Issue:8

    Topics: Acecainide; Acetylation; Adult; Female; Humans; Hydralazine; Hydrazines; Isoniazid; Lupus Erythematosus, Systemic; Lupus Vulgaris; Lymphocytes; Phenotype; Procainamide; Time Factors

1981
Effect of procainamide and hydralazine on poly (ADP-ribosylation) in cell lines.
    Lupus, 1993, Volume: 2, Issue:3

    Topics: Acecainide; Cell Line, Transformed; Humans; Hydralazine; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Procainamide; Tumor Cells, Cultured

1993