acecainide and disopyramide

acecainide has been researched along with disopyramide in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19906 (42.86)18.7374
1990's1 (7.14)18.2507
2000's5 (35.71)29.6817
2010's2 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Akazawa, M; Inui, K; Masuda, S; Okuda, M; Saito, H; Urakami, Y1
Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Garthwaite, SM; Hackett, AM; McDonald, SJ; Schneider, P; Schweingruber, F1
Roden, DM1
Lalka, D; McNamara, PJ; Pieper, JA; Slaughter, RL; Wyman, MG1
Lasky, FD; Wesley, JF1
Howanitz, JH; Howanitz, PJ1
Mohiuddin, SM; Ross, WB1
Roden, DM; Woosley, RL1

Reviews

2 review(s) available for acecainide and disopyramide

ArticleYear
Antiarrhythmic drug monitoring.
    Clinics in laboratory medicine, 1981, Volume: 1, Issue:3

    Topics: Acecainide; Anti-Arrhythmia Agents; Disopyramide; Humans; Lidocaine; Phenytoin; Procainamide; Propranolol; Quinidine

1981
Class I antiarrhythmic agents: quinidine, procainamide and N-acetylprocainamide, disopyramide.
    Pharmacology & therapeutics, 1983, Volume: 23, Issue:2

    Topics: Acecainide; Animals; Anti-Arrhythmia Agents; Disopyramide; Drug Interactions; Electrocardiography; Electrophysiology; Humans; Kinetics; Procainamide; Quinidine

1983

Other Studies

12 other study(ies) available for acecainide and disopyramide

ArticleYear
Distinct characteristics of organic cation transporters, OCT1 and OCT2, in the basolateral membrane of renal tubules.
    Pharmaceutical research, 2001, Volume: 18, Issue:11

    Topics: Animals; Cell Line; Dogs; Kidney; Kidney Tubules; Kinetics; Membranes; Nephrons; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Rats; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substrate Specificity; Tetraethylammonium; Transfection

2001
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents.
    Bioorganic & medicinal chemistry letters, 2004, Sep-20, Volume: 14, Issue:18

    Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Simple in vitro method to characterize antiarrhythmic agents.
    Journal of pharmacological methods, 1990, Volume: 23, Issue:2

    Topics: Acecainide; Animals; Anti-Arrhythmia Agents; Disopyramide; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Myocardial Contraction; Papillary Muscles; Quaternary Ammonium Compounds; Refractory Period, Electrophysiological; Sotalol; Verapamil

1990
Antiarrhythmic drugs. Clinical pharmacology of the old and the new agents.
    Postgraduate medicine, 1985, Sep-15, Volume: 78, Issue:4

    Topics: Acecainide; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Death, Sudden; Delayed-Action Preparations; Disopyramide; Heart Arrest; Humans; Lidocaine; Mexiletine; Myocardial Infarction; Procainamide; Resuscitation; Tocainide

1985
Factors influencing serum protein binding of lidocaine in humans.
    Anesthesia and analgesia, 1981, Volume: 60, Issue:6

    Topics: Acecainide; Blood Proteins; Bupivacaine; Disopyramide; Humans; Lidocaine; Orosomucoid; Procainamide; Propranolol; Protein Binding; Quinidine; Serum Albumin

1981
High performance liquid chromatographic analysis of the antiarrhythmic drugs procainamide, disopyramide, quinidine, propranolol and metabolites from serum extracts.
    Clinical biochemistry, 1981, Volume: 14, Issue:3

    Topics: Acecainide; Anti-Arrhythmia Agents; Chromatography, High Pressure Liquid; Disopyramide; Humans; Procainamide; Propranolol; Pyridines; Quinidine; Spectrophotometry, Ultraviolet

1981
Antiarrhythmic therapy: new additions and future expectations.
    Geriatrics, 1983, Volume: 38, Issue:1

    Topics: Acecainide; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Bretylium Tosylate; Disopyramide; Encainide; Humans; Lidocaine; Mexiletine; Tocainide; Verapamil

1983