acebutolol and indomethacin

acebutolol has been researched along with indomethacin in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.55)18.7374
1990's2 (9.09)18.2507
2000's9 (40.91)29.6817
2010's10 (45.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Caron, G; Ermondi, G; Lorenti, M1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Esnault, VL; Ginet, JD; Guenel, J; Le Carrer, D; Potiron-Josse, M; Testa, A1
Henry, JA; Iliopoulou, A; Kaye, CM; Sankey, MG; Turner, P1
Evans, HG; Lewis, MJ; Shah, AM1
Amira, S; Gharzouli, A; Gharzouli, K; Khennouf, S1
Adrjanowicz, K; Dulski, M; Hawelek, L; Kaczmarczyk-Sedlak, I; Kaminska, E; Kaminski, K; Kolodziejczyk, K; Mapesa, EU; Tarnacka, M; Zakowiecki, D1
Fujioka, A; Imamura, K; Imanaka, H; Ishida, N; Matsuura, T; Okamoto, T; Sekitoh, T; Takeda, K; Yamamoto, K1

Reviews

1 review(s) available for acebutolol and indomethacin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for acebutolol and indomethacin

ArticleYear
Captopril but not acebutolol, prazosin or indomethacin decreases postexercise proteinuria.
    Nephron, 1991, Volume: 58, Issue:4

    Topics: Acebutolol; Adult; Albuminuria; Captopril; Exercise; Female; Hemodynamics; Humans; Indomethacin; Prazosin; Proteinuria; Renin-Angiotensin System

1991

Other Studies

20 other study(ies) available for acebutolol and indomethacin

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Contribution of ionization and lipophilicity to drug binding to albumin: a preliminary step toward biodistribution prediction.
    Journal of medicinal chemistry, 2004, Jul-29, Volume: 47, Issue:16

    Topics: Chromatography, Affinity; Hydrogen-Ion Concentration; Ions; Models, Molecular; Molecular Conformation; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin, Bovine; Ultracentrifugation

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Changes in plasma concentrations of acebutolol, propranolol and indomethacin during physical exercise.
    Life sciences, 1981, Apr-27, Volume: 28, Issue:17

    Topics: Acebutolol; Adult; Female; Humans; Hydrogen-Ion Concentration; Indomethacin; Kinetics; Male; Physical Exertion; Propranolol

1981
Interleukin-1 beta modulates myocardial contraction via dexamethasone sensitive production of nitric oxide.
    Cardiovascular research, 1993, Volume: 27, Issue:8

    Topics: Acebutolol; Animals; Culture Techniques; Cyclic GMP; Dexamethasone; Electric Stimulation; Ferrets; Indomethacin; Interleukin-1; Myocardial Contraction; Nitric Oxide; Papillary Muscles

1993
Gastroprotective effects of honey and glucose-fructose-sucrose-maltose mixture against ethanol-, indomethacin-, and acidified aspirin-induced lesions in the rat.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2002, Volume: 54, Issue:3

    Topics: Animals; Aspirin; Carbohydrates; Ethanol; Female; Fructose; Glucose; Honey; Indomethacin; Male; Maltose; Peptic Ulcer Hemorrhage; Rats; Rats, Wistar; Stomach Ulcer; Sucrose

2002
Impact of inter- and intramolecular interactions on the physical stability of indomethacin dispersed in acetylated saccharides.
    Molecular pharmaceutics, 2014, Aug-04, Volume: 11, Issue:8

    Topics: Blood Glucose; Calorimetry, Differential Scanning; Drug Stability; Gastrointestinal Tract; Glass; Humans; Hydrogen Bonding; Indomethacin; Maltose; Molecular Conformation; Solubility; Spectrophotometry; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Sucrose; Temperature; X-Ray Diffraction

2014
Physical Stability of an Amorphous Sugar Matrix Dried From Methanol as an Amorphous Solid Dispersion Carrier and the Influence of Heat Treatment.
    Journal of pharmaceutical sciences, 2019, Volume: 108, Issue:6

    Topics: Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Curcumin; Desiccation; Drug Compounding; Drug Stability; Excipients; Hot Temperature; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Indomethacin; Maltose; Methanol; Phase Transition; Solubility; Solvents; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction

2019