acebutolol has been researched along with hydrochlorothiazide in 42 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (57.14) | 18.7374 |
| 1990's | 3 (7.14) | 18.2507 |
| 2000's | 8 (19.05) | 29.6817 |
| 2010's | 7 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Caron, G; Ermondi, G; Lorenti, M | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Akamatsu, M | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Alhenc-Gelas, F; Corvol, P; Ducrocq, MB; Menard, J; Plouin, PF | 1 |
| Karolko, B; Kopel, E; Kübler, G; Witkowska, M | 1 |
| Kolloch, R; Müller, HM; Overlack, A; Stumpe, KO | 1 |
| Behr, U; Franz, IW; Ketelhut, R; Tönnesmann, U | 1 |
| Lewis, JE | 1 |
| Boyles, PW | 1 |
| Freis, ED; Magee, PF | 1 |
| Singh, BN; Thoden, WR; Wahl, J | 1 |
| Cowling, CG; Leary, WP; Mahomedy, Y; van der Byl, K | 1 |
| Lubis, HR; Silalahi, M | 1 |
| Airoldi, G; Cagianelli, MA; Cinotti, G; Cortese, R; Diamanti, G; Giuntoli, F; Lucchini, M; Pedrinelli, R; Pettinà, G; Salvetti, A | 1 |
| Leary, WP; Reyes, AJ; van der Byl, K | 1 |
| Franz, IW | 1 |
| Drayer, JI; Weber, MA | 1 |
| Baker, PG; McGowan, GK | 1 |
| Novo, S; Scotti, A; Strano, A | 1 |
| Sugeng, I; Suryaatmaja, M; Sutandar, H; Utama, H | 1 |
| Banks, RA; Bayliss, J; MacGregor, GA; Markandu, ND; Roulston, J | 1 |
| Ramsay, LE | 1 |
| Delhotal, B; Flouvat, B; Gaillot, J; Le Liboux, A; Roux, A | 1 |
| Harvard, CW; Nievel, JG | 1 |
| Belleau, LJ; Brossard, JJ; Lebel, M | 1 |
| El Mahadi Bella, M; El Zein, O; Khalil, SI | 1 |
| Brossard, JJ; McKenzie, JK; Mitenko, PA | 1 |
| Darmadji, T; Pikir, BS; Saleh, M; Yogiarto, M | 1 |
| Brossard, JJ; Nadeau, J; Ogilvie, RI; Ruedy, J | 1 |
| Candy, GP; Radevski, IV; Sareli, P; Tshele, EF; Valtchanova, SP | 1 |
1 review(s) available for acebutolol and hydrochlorothiazide
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
19 trial(s) available for acebutolol and hydrochlorothiazide
| Article | Year |
|---|---|
[Therapy of moderate hypertension with the calcium antagonist nitrendipine in combination with beta receptor blocker or diuretic].
Topics: Acebutolol; Adult; Aged; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nitrendipine | 1990 |
[Regression of left heart hypertrophy in hypertensive patients as a result of antihypertensive therapy].
Topics: Acebutolol; Adult; Antihypertensive Agents; Atenolol; Cardiac Output; Cardiac Volume; Cardiomegaly; Drug Therapy, Combination; Echocardiography; Enalapril; Female; Gallopamil; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged; Nifedipine | 1989 |
Comparison of acebutolol and hydrochlorothiazide in essential hypertension.
Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Aged; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Placebos; Random Allocation | 1985 |
Effects of age and race on clinical response to acebutolol in essential hypertension.
Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Black People; Clinical Trials as Topic; Double-Blind Method; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Placebos; Propranolol; Random Allocation | 1985 |
Is low-dose hydrochlorothiazide effective?
Topics: Acebutolol; Aged; Blood Pressure; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enalapril; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nadolol; Potassium; Propanolamines | 1986 |
Comparative hypotensive effects of acebutolol and hydrochlorothiazide in patients with mild to moderate essential hypertension: a double-blind multicenter evaluation.
Topics: Acebutolol; Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged | 1986 |
Antihypertensive effects of acebutolol plus hydrochlorothiazide and hydrochlorothiazide alone in black patients.
Topics: Acebutolol; Adult; Black People; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Random Allocation; Urban Population | 1986 |
A comparative study of two beta-blocker-diuretic combinations in the treatment of hypertension.
Topics: Acebutolol; Adult; Aged; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Propranolol | 1986 |
Multicentre comparison of the antihypertensive effect of acebutolol and hydrochlorothiazide in uncomplicated mild-moderate hypertension in the elderly.
Topics: Acebutolol; Aged; Blood Pressure; Clinical Trials as Topic; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Random Allocation; Time Factors | 1985 |
Single-agent and combination therapy of essential hypertension.
Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Aldosterone; Blood Pressure; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged; Propranolol; Renin-Angiotensin System | 1984 |
Treatment of essential hypertension with beta-blocker plus diuretic: a study of 1402 patients treated by general practitioners with acebutolol 200 mg combined with hydrochlorothiazide 12.5 mg ('Secadrex') once daily for 3 months.
Topics: Acebutolol; Adult; Aged; Blood Pressure; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Family Practice; Fatigue; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nausea; Pulse; Vomiting | 1984 |
[Controlled clinical study on the effects of acebutolol in comparison with hydrochlorothiazide in the aged hypertensive].
Topics: Acebutolol; Aged; Blood Pressure; Clinical Trials as Topic; Heart Rate; Humans; Hydrochlorothiazide; Hypertension | 1983 |
The efficacy and acceptability of the combination of acebutolol and hydrochlorothiazide in the treatment of essential hypertension.
Topics: Acebutolol; Adult; Aged; Blood Pressure; Clinical Trials as Topic; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Pulse; Time Factors; Uric Acid | 1984 |
Lack of effect of beta-blocker on flat dose response to thiazide in hypertension: efficacy of low dose thiazide combined with beta-blocker.
Topics: Acebutolol; Adult; Body Weight; Chlorides; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Random Allocation; Renin; Urea | 1983 |
Assessment of the efficacy and acceptability of an acebutolol/hydrochlorothiazide combination in the treatment of mild to moderate essential hypertension.
Topics: Acebutolol; Adult; Aged; Blood Pressure; Clinical Trials as Topic; Drug Combinations; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Posture; Potassium | 1981 |
Merits of adding a beta blocker (acebutolol) to a diuretic (hydrochlorothiazide) in the treatment of hypertension.
Topics: Acebutolol; Adult; Aldosterone; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Renin | 1982 |
A double-blind, crossover study of acebutolol and hydrochlorothiazide/amiloride diuretic in Sudanese patients with essential hypertension.
Topics: Acebutolol; Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Pulse; Pyrazines; Sudan | 1982 |
Antihypertensive action of acebutolol (Sectral) when used concomitantly with hydrochlorothiazide.
Topics: Acebutolol; Adult; Blood Pressure; Drug Evaluation; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium | 1982 |
Comparison of acebutolol with and without hydrochlorothiazide versus carvedilol with and without hydrochlorothiazide in black patients with mild to moderate systemic hypertension.
Topics: Acebutolol; Adrenergic beta-Antagonists; Antihypertensive Agents; Black People; Blood Pressure; Carbazoles; Carvedilol; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pilot Projects; Propanolamines; Prospective Studies; Sodium Chloride Symporter Inhibitors; Time Factors | 1999 |
22 other study(ies) available for acebutolol and hydrochlorothiazide
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Contribution of ionization and lipophilicity to drug binding to albumin: a preliminary step toward biodistribution prediction.
Topics: Chromatography, Affinity; Hydrogen-Ion Concentration; Ions; Models, Molecular; Molecular Conformation; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin, Bovine; Ultracentrifugation | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
QSAR study on permeability of hydrophobic compounds with artificial membranes.
Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship | 2007 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Importance of physicochemical properties for the design of new pesticides.
Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic | 2011 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Comparison of the antihypertensive and hormonal effects of a cardioselective beta-blocker, acebutolol, and diuretics in essential hypertension.
Topics: Acebutolol; Adult; Aldosterone; Amiloride; Blood Pressure; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Renin; Spironolactone | 1978 |
[Does chronic therapy of hypertension with acebutolol or hydrochlorothiazide effect coronary risk factors?].
Topics: Acebutolol; Adult; Coronary Disease; Female; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Risk Factors | 1991 |
Effects of an acebutolol-hydrochlorothiazide combination on urinary solute excretion in healthy adults.
Topics: Acebutolol; Adolescent; Adult; Calcium; Chlorides; Creatinine; Drug Interactions; Electrolytes; Humans; Hydrochlorothiazide; Magnesium; Male; Phosphates; Potassium; Sodium; Time Factors; Zinc | 1986 |
Differential antihypertensive effect of acebutolol and hydrochlorothiazide/amiloride hydrochloride combination on elevated exercise blood pressures in hypertensive patients.
Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Amiloride; Antihypertensive Agents; Blood Pressure; Diuretics; Drug Therapy, Combination; Exercise Test; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pyrazines; Sodium Chloride Symporter Inhibitors | 1980 |
Beta blockers and flat dose response to thiazide in hypertension.
Topics: Acebutolol; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension | 1983 |
Pharmacokinetics in man of acebutolol and hydrochlorothiazide as single agents and in combination.
Topics: Acebutolol; Adult; Drug Combinations; Humans; Hydrochlorothiazide; Kinetics; Male | 1983 |
The use of acebutolol with hydrochlorothiazide in hypertension.
Topics: Acebutolol; Adult; Aged; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Female; Follow-Up Studies; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged | 1981 |
Acebutolol and hydrochlorothiazide in essential hypertension.
Topics: Acebutolol; Adult; Aged; Blood Pressure; Double-Blind Method; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Random Allocation | 1980 |