Compounds > abt 702

abt 702 and adenosine

abt 702 has been researched along with adenosine in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's11 (91.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bhagwat, SS; Boyle, DL; Firestein, GS; Jarvis, MF; Kowaluk, EA; Lee, CH; Williams, M1
Bache, RJ; Chen, Y; Fassett, JT; Hu, X; Lu, Z; Xu, X; Zhang, P1
Boison, D; Chen, JF; Lan, JQ; Lytle, N; Shen, HY; Singer, P; Wei, CJ; Williams-Karnesky, RL; Yee, BK1
Bachtell, RK; Hobson, BD; Merritt, KE1
Ahmad, S; Al-Gayyar, MM; Eissa, LA; El-Shishtawy, MM; Elsherbini, AM; Elsherbiny, NM; Fulzele, S; Liou, GI; Naime, M1
Dierckx, RA; Elsinga, PH; Ishiwata, K; Khanapur, S; Meerlo, P; Paul, S; Sijbesma, JW; van Waarde, A1
Bannister, K; Chen, Z; Dickenson, AH; Doyle, T; Ford, A; Jacobson, KA; Janes, K; Little, JW; Luongo, L; Maione, S; Porreca, F; Salvemini, D; Symons-Liguori, AM; Tosh, DK; Vanderah, TW; Xie, J1
Ahmad, S; Bhatia, K; Elsherbini, AM; Elsherbiny, NM; Fulzele, S; Liou, GI1
Gotoh, A; Kanno, T; Kuribayashi, K; Nagaya, T; Nakajima, Y; Nakano, T; Nishizaki, T1
Ito, S; Kon, Y; Otsuguro, K; Otsuka, S; Tomonari, Y; Yamaguchi, S1
Ko, JH; Mzengeza, S; Parkinson, FE; Paul, S; Zhang, D1
An, X; Cao, W; Huang, Z; Li, Q; Liu, X; Wu, L; Xing, C; Yuan, Y; Zhang, A; Zhang, B1

Other Studies

12 other study(ies) available for abt 702 and adenosine

ArticleYear
Anti-inflammatory effects of ABT-702, a novel non-nucleoside adenosine kinase inhibitor, in rat adjuvant arthritis.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 296, Issue:2

    Topics: Adenosine; Adenosine Kinase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Biotransformation; Blotting, Northern; Bone and Bones; Cell Nucleus; Enzyme Inhibitors; Freund's Adjuvant; Gene Expression Regulation, Enzymologic; Indicators and Reagents; Male; Matrix Metalloproteinases; Morpholines; Pyrimidines; Rats; Rats, Inbred Lew

2001
Adenosine kinase regulation of cardiomyocyte hypertrophy.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 300, Issue:5

    Topics: Adenosine; Adenosine Kinase; AMP-Activated Protein Kinase Kinases; Animals; Cells, Cultured; Enzyme Inhibitors; Hypertrophy; Models, Animal; Morpholines; Myocytes, Cardiac; Protein Kinases; Pyrimidines; raf Kinases; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Signal Transduction; TOR Serine-Threonine Kinases

2011
Adenosine augmentation ameliorates psychotic and cognitive endophenotypes of schizophrenia.
    The Journal of clinical investigation, 2012, Volume: 122, Issue:7

    Topics: Adenosine; Adenosine Kinase; Amphetamines; Animals; Antipsychotic Agents; Basal Ganglia; Cell Transplantation; Cells, Cultured; Cognition Disorders; Cricetinae; Disease Models, Animal; Endophenotypes; Hippocampus; Mice; Mice, Inbred C57BL; Mice, Transgenic; Morpholines; Psychotic Disorders; Pyrimidines; Receptor, Adenosine A2A; Schizophrenia; Schizophrenic Psychology

2012
Stimulation of adenosine receptors in the nucleus accumbens reverses the expression of cocaine sensitization and cross-sensitization to dopamine D2 receptors in rats.
    Neuropharmacology, 2012, Volume: 63, Issue:6

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Cocaine; Dopamine Agonists; Dopamine Uptake Inhibitors; Male; Microinjections; Morpholines; Motor Activity; Nucleus Accumbens; Phenethylamines; Pyrimidines; Quinpirole; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Dopamine D2; Receptors, Purinergic P1; Stimulation, Chemical

2012
ABT-702, an adenosine kinase inhibitor, attenuates inflammation in diabetic retinopathy.
    Life sciences, 2013, Jul-30, Volume: 93, Issue:2-3

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Adenosine Kinase; Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Enzyme Inhibitors; Equilibrative Nucleoside Transporter 1; Glycated Serum Albumin; Glycation End Products, Advanced; Intercellular Adhesion Molecule-1; Male; Mice; Mice, Inbred C57BL; Microglia; Molecular Targeted Therapy; Morpholines; Oxidative Stress; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Retinitis; Serum Albumin; Tumor Necrosis Factor-alpha

2013
Use of 11C-MPDX and PET to study adenosine A1 receptor occupancy by nonradioactive agonists and antagonists.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2014, Volume: 55, Issue:2

    Topics: Adenosine; Allosteric Site; Animals; Brain; Caffeine; Carbon Radioisotopes; Ethanol; Heart Rate; Male; Morpholines; Positron-Emission Tomography; Pyrimidines; Radiopharmaceuticals; Rats; Rats, Wistar; Receptor, Adenosine A1; Xanthines

2014
Endogenous adenosine A3 receptor activation selectively alleviates persistent pain states.
    Brain : a journal of neurology, 2015, Volume: 138, Issue:Pt 1

    Topics: Adenosine; Animals; Disease Models, Animal; Gene Expression Regulation; Hyperalgesia; Male; Medulla Oblongata; Mice; Mice, Inbred C57BL; Mice, Transgenic; Morpholines; Naloxone; Neuralgia; Neurons; Pain Measurement; Pain Threshold; Purinergic P1 Receptor Antagonists; Pyridines; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A3; Spinal Cord; Time Factors

2015
Inhibition of adenosine kinase attenuates inflammation and neurotoxicity in traumatic optic neuropathy.
    Journal of neuroimmunology, 2014, Dec-15, Volume: 277, Issue:1-2

    Topics: Adenosine; Adenosine Kinase; Animals; Anti-Inflammatory Agents; Calcium-Binding Proteins; Cells, Cultured; Disease Models, Animal; Enzyme Inhibitors; Equilibrative Nucleoside Transporter 1; Imidazoles; Inflammation; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Microfilament Proteins; Microglia; Morpholines; Neurotoxicity Syndromes; Nitric Oxide Synthase Type I; Optic Nerve Injuries; Oxidative Stress; Pyridines; Pyrimidines; Retina

2014
Adenosine deaminase inhibitor EHNA exhibits a potent anticancer effect against malignant pleural mesothelioma.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2015, Volume: 35, Issue:1

    Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Humans; Mesothelioma; Mice; Mice, Nude; Morpholines; Pleural Neoplasms; Pyrimidines; RNA Interference; RNA, Small Interfering; Transplantation, Heterologous

2015
An adenosine kinase inhibitor, ABT-702, inhibits spinal nociceptive transmission by adenosine release via equilibrative nucleoside transporters in rat.
    Neuropharmacology, 2015, Volume: 97

    Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Deaminase; Adenosine Kinase; Analgesics; Animals; Animals, Newborn; Enzyme Inhibitors; Membrane Potentials; Morpholines; Motor Neurons; Neural Pathways; Nociceptive Pain; Pyrimidines; Reflex; Spinal Cord; Tissue Culture Techniques; Xanthines

2015
The Effect of Endogenous Adenosine on Neuronal Activity in Rats: An FDG PET Study.
    Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2016, Volume: 26, Issue:4

    Topics: Adenosine; Animals; Brain; Brain Mapping; Fluorodeoxyglucose F18; Glucose; Glycolysis; Humans; Image Processing, Computer-Assisted; Male; Morpholines; Positron-Emission Tomography; Pyrimidines; Rats; Receptor, Adenosine A1; Xanthines

2016
Adenosine kinase inhibition protects against cisplatin-induced nephrotoxicity.
    American journal of physiology. Renal physiology, 2019, 07-01, Volume: 317, Issue:1

    Topics: Acute Kidney Injury; Adenosine; Adenosine Kinase; Animals; Apoptosis; Cell Line; Cisplatin; Disease Models, Animal; Humans; Inflammation Mediators; Kidney; Male; Mice, Inbred C57BL; Morpholines; Oxidative Stress; Protein Kinase Inhibitors; Pyrimidines; Reactive Oxygen Species; Receptors, Purinergic P1; Signal Transduction; Up-Regulation

2019