Compounds > abiraterone
Page last updated: 2024-09-04

abiraterone and mitoxantrone

abiraterone has been researched along with mitoxantrone in 7 studies

Compound Research Comparison

Studies
(abiraterone)		Trials
(abiraterone)		Recent Studies (post-2010)
(abiraterone)		Studies
(mitoxantrone)		Trials
(mitoxantrone)		Recent Studies (post-2010) (mitoxantrone)
942978544,5551,0421,004

Protein Interaction Comparison

ProteinTaxonomyabiraterone (IC50)mitoxantrone (IC50)
Chain A, Probable serine/threonine-protein kinase pknBMycobacterium tuberculosis H37Rv0.8
nonstructural protein 1Influenza A virus (A/California/07/2009(H1N1))2.049
rac GTPase-activating protein 1 isoform aHomo sapiens (human)14.46
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)3.5619
Epidermal growth factor receptorHomo sapiens (human)5.3859
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)2.0352
Tyrosine-protein kinase FynHomo sapiens (human)1.2579
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)4.9898
Muscarinic acetylcholine receptor M2Homo sapiens (human)0.219
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.6441
ATP-dependent translocase ABCB1Homo sapiens (human)1.501
Proto-oncogene tyrosine-protein kinase ROSHomo sapiens (human)2.9987
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.7487
DNA topoisomerase 2-alphaHomo sapiens (human)5.3
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)1.7853
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)3.5849
Casein kinase II subunit alpha'Homo sapiens (human)0.66
Sodium-dependent noradrenaline transporter Homo sapiens (human)4.9898
5-hydroxytryptamine receptor 2CHomo sapiens (human)3.5619
Multidrug resistance-associated protein 1 Homo sapiens (human)0.0081
Casein kinase II subunit betaHomo sapiens (human)0.66
Casein kinase II subunit alphaHomo sapiens (human)0.66
Tyrosine-protein kinase BTKHomo sapiens (human)1
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)3.5849
TAR DNA-binding protein 43Homo sapiens (human)10
Nuclear receptor subfamily 3 group C member 3 Bos taurus (cattle)3.5849
Integrase Human immunodeficiency virus 15.9
Multidrug and toxin extrusion protein 2Homo sapiens (human)0.68
Casein kinase II subunit alpha 3Homo sapiens (human)0.66
Multidrug and toxin extrusion protein 1Homo sapiens (human)0.3733
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)3.39
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)0.9038

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alhasso, A; Ansari, A; Ansari, J; Glaholm, J; Hussain, SA; Mahmood, R1
Börgermann, C; Molitor, B1
D'Amico, AV1
Bahl, A1
Ndibe, C; Sonpavde, G; Wang, CG1
Bertaglia, V; Buttigliero, C; Di Maio, M; Scagliotti, GV; Tucci, M; Vignani, F1
Baldauf, S; Bartsch, G; Borgmann, H; Brandt, MP; Dotzauer, R; Frees, S; Haferkamp, A; Jäger, W; Neisius, A; Schneider, M; Thomas, C; Tsaur, I1

Reviews

5 review(s) available for abiraterone and mitoxantrone

ArticleYear
Role of second-line systemic treatment post-docetaxel in metastatic castrate resistant prostate cancer- current strategies and future directions.
    Anti-cancer agents in medicinal chemistry, 2011, Volume: 11, Issue:3

    Topics: Androstenes; Androstenols; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Disease Progression; Disease-Free Survival; Docetaxel; Drug Resistance, Neoplasm; Forecasting; Humans; Male; Mitoxantrone; Neoplasm Metastasis; Prednisolone; Prostatic Neoplasms; Quality of Life; Taxoids; Treatment Failure

2011
[Second line therapy for castration-resistant prostate cancer (CRPC)].
    Der Urologe. Ausg. A, 2012, Volume: 51, Issue:3

    Topics: Androstenes; Androstenols; Antineoplastic Combined Chemotherapy Protocols; Cancer Vaccines; Clinical Trials as Topic; Combined Modality Therapy; Docetaxel; Humans; Male; Mitoxantrone; Neoplasm Recurrence, Local; Orchiectomy; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; Survival Rate; Taxoids; Tissue Extracts

2012
Metastatic castration-resistant prostate cancer. Part 1: the challenges of the disease and its treatment.
    European journal of oncology nursing : the official journal of European Oncology Nursing Society, 2013, Volume: 17 Suppl 1

    Topics: Alpha Particles; Androstenes; Androstenols; Antineoplastic Agents; Benzamides; Cancer Vaccines; Chlorides; Docetaxel; Humans; Male; Mitoxantrone; Neoplasm Grading; Neoplasm Metastasis; Neoplasm Staging; Nitriles; Phenylthiohydantoin; Prognosis; Prostatic Neoplasms, Castration-Resistant; Quality of Life; Radioisotopes; Radium; Taxoids; Tissue Extracts

2013
Corticosteroids in the management of prostate cancer: a critical review.
    Current treatment options in oncology, 2015, Volume: 16, Issue:2

    Topics: Adrenal Cortex Hormones; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Drug Resistance, Neoplasm; Humans; Male; Mitoxantrone; Palliative Care; Prednisone; Prostatic Neoplasms, Castration-Resistant; Taxoids; Treatment Outcome

2015
Skeletal metastases and impact of anticancer and bone-targeted agents in patients with castration-resistant prostate cancer.
    Cancer treatment reviews, 2016, Volume: 44

    Topics: Androstenes; Anilides; Antineoplastic Agents; Benzamides; Bone Density Conservation Agents; Bone Neoplasms; Carcinoma; Dasatinib; Denosumab; Diphosphonates; Docetaxel; Humans; Imidazoles; Male; Mitoxantrone; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Pyridines; Radioisotopes; Radium; Taxoids; Zoledronic Acid

2016

Other Studies

2 other study(ies) available for abiraterone and mitoxantrone

ArticleYear
US Food and Drug Administration approval of drugs for the treatment of prostate cancer: a new era has begun.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Feb-01, Volume: 32, Issue:4

    Topics: Androstenes; Androstenols; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzamides; Denosumab; Diphosphonates; Docetaxel; Drug Approval; Drugs, Investigational; Estramustine; Goserelin; Humans; Imidazoles; Male; Mitoxantrone; Nitriles; Oligopeptides; Phenylthiohydantoin; Prostatic Neoplasms; Radioisotopes; Radium; Taxoids; Tissue Extracts; United States; United States Food and Drug Administration; Zoledronic Acid

2014
Docetaxel-rechallenge in castration-resistant prostate cancer: defining clinical factors for successful treatment response and improvement in overall survival.
    International urology and nephrology, 2018, Volume: 50, Issue:10

    Topics: Aged; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Disease-Free Survival; Docetaxel; Follow-Up Studies; Gonadotropin-Releasing Hormone; Humans; Lymphatic Metastasis; Male; Middle Aged; Mitoxantrone; Neoplasm Grading; Orchiectomy; Prostate-Specific Antigen; Prostatectomy; Prostatic Neoplasms, Castration-Resistant; Retreatment; Retrospective Studies; Survival Rate; Taxoids

2018