abecarnil has been researched along with flumazenil in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (64.29) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cook, JM; Dayer, CA; He, X; Huang, Q; Liu, R; Ma, C; McKernan, R; Wenger, GR; Yu, S | 1 |
| Clayton, T; Cook, J; DeLorey, TM; Furtmüller, R; Halliwell, RF; Harris, D; Huck, S; Sahbaie, P; Sieghart, W | 1 |
| Hönack, D; Löscher, W | 1 |
| Frey, HH; Hashem, A; Hönack, D; Löscher, W; Scherkl, R | 1 |
| Emmett-Oglesby, MW; English, SA; Lytle, DA | 1 |
| Akai, T; Kuno, S; Mizuta, E; Nakada, Y; Ozawa, M; Sugimachi, K; Yabuuchi, F; Yamaguchi, M | 1 |
| Biggio, G; Dazzi, L; Gessa, GL; Imperato, A; Serra, M | 1 |
| Biggio, G; Dazzi, L; Maira, G; Motzo, C; Sanna, A; Serra, M | 1 |
| Hadingham, KL; Palmer, KJ; Thompson, SA; Wafford, KA; Whiting, PJ | 1 |
| Hansen, HC; Jackson, HC; Judge, ME; Klitgaard, H; Kristiansen, M; Suzdak, PD; Swedberg, MD | 1 |
| Contarino, A; Giusti, P; Lipartiti, M; Natolino, F; Zanotti, A | 1 |
| Elliot, EE; White, JM | 1 |
| Depoortere, R; Jung, ME; Oglesby, MW | 1 |
| Groenwold, RH; Kasteleijn-Nolst Trenité, DG; Löscher, W; Schmidt, B | 1 |
1 trial(s) available for abecarnil and flumazenil
| Article | Year |
|---|---|
Single dose efficacy evaluation of two partial benzodiazepine receptor agonists in photosensitive epilepsy patients: A placebo-controlled pilot study.
Topics: Administration, Oral; Adolescent; Adult; Anticonvulsants; Brain; Carbolines; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Reflex; Female; Flumazenil; GABA-A Receptor Agonists; Humans; Male; Middle Aged; Molecular Structure; Photic Stimulation; Pilot Projects; Receptors, GABA-A; Single-Blind Method; Young Adult | 2016 |
13 other study(ies) available for abecarnil and flumazenil
| Article | Year |
|---|---|
Pharmacophore/receptor models for GABA(A)/BzR subtypes (alpha1beta3gamma2, alpha5beta3gamma2, and alpha6beta3gamma2) via a comprehensive ligand-mapping approach.
Topics: Animals; Benzodiazepines; Carbolines; Cell Line; Columbidae; Conditioning, Operant; Crystallography, X-Ray; Humans; Indoles; Ligands; Male; Models, Molecular; Pyrimidines; Quinolones; Radioligand Assay; Receptors, GABA-A; Saimiri; Stereoisomerism; Structure-Activity Relationship | 2000 |
Selective influence on contextual memory: physiochemical properties associated with selectivity of benzodiazepine ligands at GABAA receptors containing the alpha5 subunit.
Topics: Animals; Behavior, Animal; Benzodiazepines; Chemical Phenomena; Chemistry, Physical; Computer Simulation; Databases, Factual; Electrophysiology; Female; Ligands; Male; Memory; Mice; Models, Molecular; Molecular Structure; Oocytes; Protein Isoforms; Protein Subunits; Quantitative Structure-Activity Relationship; Receptors, GABA-A; Structure-Activity Relationship; Xenopus laevis | 2008 |
Withdrawal precipitation by benzodiazepine receptor antagonists in dogs chronically treated with diazepam or the novel anxiolytic and anticonvulsant beta-carboline abecarnil.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Carbolines; Diazepam; Dogs; Female; Flumazenil; GABA-A Receptor Antagonists; Oxazepam; Substance Withdrawal Syndrome | 1992 |
Pharmacokinetics, anticonvulsant efficacy and adverse effects of the beta-carboline abecarnil, a novel ligand for benzodiazepine receptors, after acute and chronic administration in dogs.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Blood Pressure; Carbolines; Dogs; Female; Flumazenil; Heart Rate; Male; Motor Activity; Receptors, GABA-A; Respiration; Substance-Related Disorders | 1990 |
Abecarnil used to treat benzodiazepine withdrawal.
Topics: Animals; Anti-Anxiety Agents; Carbolines; Chlordiazepoxide; Cues; Discrimination Learning; Flumazenil; Male; Rats; Substance Withdrawal Syndrome | 1993 |
Pharmacological characterization of the novel anxiolytic beta-carboline abecarnil in rodents and primates.
Topics: Aggression; Animals; Anti-Anxiety Agents; Behavior, Animal; Benzodiazepines; Binding, Competitive; Carbolines; Cerebellum; Flumazenil; Hexobarbital; Kidney; Macaca fascicularis; Male; Mice; Mice, Inbred ICR; Motor Activity; Rats; Rats, Wistar; Receptors, GABA-A; Reflex; Spinal Cord; Tritium | 1994 |
Differential effects of abecarnil on basal release of acetylcholine and dopamine in the rat brain.
Topics: Acetylcholine; Animals; Anti-Anxiety Agents; Brain; Carbolines; Diazepam; Dopamine; Flumazenil; GABA-A Receptor Agonists; Hippocampus; Male; Microdialysis; Neurons; Prefrontal Cortex; Rats; Rats, Sprague-Dawley | 1994 |
Enhancement of acetylcholine release by flumazenil in the hippocampus of rats chronically treated with diazepam but not with imidazenil or abecarnil.
Topics: Acetylcholine; Animals; Anticonvulsants; Benzodiazepines; Carbolines; Diazepam; Flumazenil; GABA Modulators; Hippocampus; Imidazoles; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Time Factors | 1995 |
Expression and pharmacology of human GABAA receptors containing gamma 3 subunits.
Topics: Amino Acid Sequence; Animals; Anti-Anxiety Agents; Base Sequence; Benzodiazepines; Benzodiazepinones; Carbolines; Flumazenil; Flunitrazepam; GABA Modulators; Humans; Molecular Sequence Data; Pyrazoles; Pyridazines; Pyridines; Receptors, GABA-A; Recombinant Proteins; Sequence Homology, Amino Acid; Triazolam; Xenopus; Zolpidem | 1995 |
Anticonvulsant profile of the imidazoquinazolines NNC 14-0185 and NNC 14-0189 in rats and mice.
Topics: Acoustic Stimulation; Amygdala; Animals; Anticonvulsants; Bicuculline; Carbolines; Clonazepam; Diazepam; Electroshock; Flumazenil; GABA Modulators; GABA-A Receptor Agonists; Kindling, Neurologic; Male; Mice; Mice, Inbred DBA; Mice, Inbred Strains; Pentylenetetrazole; Quinazolines; Rats; Rats, Wistar; Seizures | 1996 |
Abecarnil enhances recovery from diazepam tolerance.
Topics: Animals; Anticonvulsants; Benzodiazepines; Bicuculline; Carbolines; Cell Membrane; Cerebral Cortex; Clonazepam; Diazepam; Drug Interactions; Drug Tolerance; Flumazenil; Imidazoles; Ligands; Male; Mice; Receptors, GABA-A; Seizures; Tritium | 1999 |
Long-term abecarnil administration produces tolerance and withdrawal signs in the rat.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Body Temperature; Carbolines; Drug Tolerance; Electromyography; Flumazenil; GABA Modulators; Male; Motor Activity; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Telemetry | 2000 |
Use of negatively reinforcing electrical brain stimulation to detect conventional and nonconventional anxiolytics as well as an anxiogenic drug.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Brain; Buspirone; Carbolines; Convulsants; Diazepam; Electric Stimulation; Electrodes; Flumazenil; GABA Modulators; Male; Pentylenetetrazole; Rats; Rats, Long-Evans; Reinforcement, Psychology | 2001 |