Compounds > aaptamine
Page last updated: 2024-09-03

aaptamine and isoaaptamine

aaptamine has been researched along with isoaaptamine in 8 studies

Compound Research Comparison

Studies
(aaptamine)		Trials
(aaptamine)		Recent Studies (post-2010)
(aaptamine)		Studies
(isoaaptamine)		Trials
(isoaaptamine)		Recent Studies (post-2010) (isoaaptamine)
460291403

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's4 (50.00)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Duh, CY; Lin, TT; Shen, YC; Sheu, JH1
Gerwick, WH; Hamann, MT; Hodges, TW; Nagle, DG; Rajbhandari, I; Takamatsu, S1
Albright, L; Chapuis, JC; Doubek, DL; Herald, DL; Higgs, KC; Hoffmann, H; Hooper, JN; McNulty, J; Molloy, DJ; Murphy, A; Pettit, GR; Pettit, RK; Schmidt, JM; Tackett, LP; Williams, MD1
Chung, SC; Jang, KH; Kim, TI; Lee, HS; Lee, SH; Oh, KB; Shin, J1
de Voogd, NJ; Ikeda, T; Mangindaan, RE; Rotinsulu, H; Sato, K; Tsukamoto, S; van Soest, RW; Yamanokuchi, R; Yokosawa, H; Yoshitomi, M1
Blumberg, PM; Hamel, E; Herald, DL; Higgs, KC; Hoffmann, H; Knight, JC; Lewin, NE; McNulty, J; Murphy, A; Pearce, LV; Pettit, GR; Pettit, RK1
Balabanov, S; Bokemeyer, C; Dyshlovoy, SA; Fedorov, SN; Honecker, F; Jacobsen, C; Shubina, LK; Stonik, VA; Venz, S; Walther, R1
El-Shazly, M; Hong, MC; Ke, SC; Lai, KH; Lee, MG; Lu, MC; Shih, SP; Su, CW; Sung, PJ; Wen, ZH; Wu, CF1

Other Studies

8 other study(ies) available for aaptamine and isoaaptamine

ArticleYear
Structures and cytotoxicity relationship of isoaaptamine and aaptamine derivatives.
    Journal of natural products, 1999, Volume: 62, Issue:9

    Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Humans; Mice; Molecular Structure; Naphthyridines; Porifera; Spectrum Analysis; Structure-Activity Relationship; Tumor Cells, Cultured

1999
Marine natural products as novel antioxidant prototypes.
    Journal of natural products, 2003, Volume: 66, Issue:5

    Topics: Animals; Antioxidants; Biological Products; Biphenyl Compounds; Cyanobacteria; Eukaryota; Jamaica; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Picrates; Porifera; Stereoisomerism

2003
Antineoplastic agents. 380. Isolation and X-ray crystal structure determination of isoaaptamine from the Republic of Singapore Hymeniacidon sp. and conversion to the phosphate prodrug hystatin 1.
    Journal of natural products, 2004, Volume: 67, Issue:3

    Topics: Animals; Antineoplastic Agents; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Leukemia P388; Molecular Structure; Naphthyridines; Oceans and Seas; Phosphates; Porifera; Prodrugs; Tumor Cells, Cultured

2004
Aaptamines as sortase A inhibitors from the tropical sponge Aaptos aaptos.
    Bioorganic & medicinal chemistry letters, 2007, Oct-01, Volume: 17, Issue:19

    Topics: Aminoacyltransferases; Animals; Anti-Bacterial Agents; Bacterial Proteins; Chromatography, Gel; Chromatography, High Pressure Liquid; Cysteine Endopeptidases; Enzyme Inhibitors; Fibronectins; Microbial Sensitivity Tests; Naphthyridines; Porifera; Protein Binding; Staphylococcus aureus

2007
Aaptamine, an alkaloid from the sponge Aaptos suberitoides, functions as a proteasome inhibitor.
    Bioorganic & medicinal chemistry letters, 2010, Jun-01, Volume: 20, Issue:11

    Topics: Animals; HeLa Cells; Humans; Naphthyridines; Porifera; Protease Inhibitors; Proteasome Inhibitors

2010
Antineoplastic agents 491. Synthetic conversion of aaptamine to isoaaptamine, 9-demethylaaptamine, and 4-methylaaptamine.
    The Journal of organic chemistry, 2004, Apr-02, Volume: 69, Issue:7

    Topics: Animals; Antineoplastic Agents; Bacteria; Candida albicans; Cryptococcus neoformans; Drug Screening Assays, Antitumor; Leukemia P388; Mice; Microbial Sensitivity Tests; Molecular Structure; Naphthyridines; Porifera; Structure-Activity Relationship; Tumor Cells, Cultured

2004
Activity of aaptamine and two derivatives, demethyloxyaaptamine and isoaaptamine, in cisplatin-resistant germ cell cancer.
    Journal of proteomics, 2014, Jan-16, Volume: 96

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cisplatin; Drug Resistance, Neoplasm; Humans; Naphthyridines; Neoplasms, Germ Cell and Embryonal

2014
Isoaaptamine Induces T-47D Cells Apoptosis and Autophagy via Oxidative Stress.
    Marine drugs, 2018, Jan-09, Volume: 16, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagy; Breast Neoplasms; DNA Damage; Dose-Response Relationship, Drug; Female; Flow Cytometry; Humans; Membrane Potential, Mitochondrial; Microscopy, Electron, Transmission; Naphthyridines; Oxidative Stress; Porifera; Reactive Oxygen Species

2018