aa 861 and leukotriene b4
aa 861 has been researched along with leukotriene b4 in 47 studies
Research
Studies (47)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (27.66) | 18.7374 |
| 1990's | 20 (42.55) | 18.2507 |
| 2000's | 11 (23.40) | 29.6817 |
| 2010's | 3 (6.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Haston, WO; Morrissey, MM; Quintavalla, JC; Rediske, JJ; Seligman, B | 1 |
| Justen, JM; Leach, KL; Sam, LM; Smith, RJ | 1 |
| Abe, M; Shigematsu, N; Tanaka, K | 1 |
| Abe, S; Katayama, K; Katayama, S; Sakuma, Y; Tsunoda, H; Yamatsu, I | 2 |
| Dziak, R; Ren, W | 1 |
| Abe, S; Katayama, K; Katayama, S; Sakuma, Y; Tanaka, S; Tsukidate, K; Tsunoda, H; Yamatsu, I | 1 |
| Horichi, H; Izumi, R; Kitabayashi, K; Konishi, K; Miyazaki, I; Shimizu, K; Watanabe, T | 1 |
| Hara, A; Ikeda, M; Kaneko, H; Shiba, T; Takeuchi, S; Yoshida, H | 1 |
| Kawana, S; Nishiyama, S; Ueno, A | 1 |
| Nakaguma, H; Takahashi, H | 1 |
| Dziak, R; Mohammed, AH; Tatakis, DN | 1 |
| Kobayashi, K; Mizoguchi, Y; Morisawa, S; Sakagami, Y; Seki, S; Yamamoto, S | 1 |
| Arakawa, T; Fukuda, T; Kobayashi, K; Nakamura, H; Nebiki, H; Torii, Y | 1 |
| Katori, M; Kawamura, M; Kikawada, R; Sasaki, K; Shigehiro, S; Ueno, A | 1 |
| Colombo, C; Dotson, R; Ghai, G; Kimble, EF; Ku, EC; Lee, WH; Oglesby, TD; Raychaudhuri, A; Wasley, JW | 1 |
| Ashida, Y; Kuriki, H; Maki, Y; Makino, H; Saijo, T; Terao, S | 2 |
| Hirai, A; Saito, H; Tahara, K; Tamura, Y; Terano, T; Yoshida, S | 1 |
| Schulz, R; Seeger, W | 1 |
| Ozawa, T; Satake, T; Sugiyama, S; Takagi, K; Taki, F; Taniguchi, H | 1 |
| Niwa, Y; Ohashi, T; Ozaki, Y | 1 |
| Mita, H; Shida, T; Yui, Y | 1 |
| Atluru, D; Sayana, U; Schultz, RD; Yang, WC | 1 |
| Fujimoto, K; Kobayashi, T; Kubo, K; Matsuzawa, Y; Okada, K; Shinozaki, S; Sugane, K | 1 |
| Kimura, J; Namura, Y; Shio, H | 1 |
| Fukushima, W; Hashimoto, T; Horichi, H; Ii, T; Iwasa, K; Iyobe, T; Izumi, R; Shimizu, K; Watanabe, T; Yagi, M | 1 |
| Bye, A; Robinson, C; Summers, JA | 1 |
| Coffey, CS; Coffey, RG; Diaz, S | 1 |
| Izumi, R; Kitagawa, H; Urade, M | 1 |
| Kikuchi, M; Naito, K; Tsuzurahara, K | 1 |
| Izumi, T; Koyama, S; Kubo, K; Nagai, S; Nomura, H; Sato, E | 1 |
| Kawauchi, Y; Masuho, Y; Takasaki, J | 1 |
| Ibe, BO; Raj, JU | 1 |
| Haniuda, M; Izumi, T; Koyama, S; Kubo, K; Nagai, S; Nomura, H; Sato, E | 1 |
| Antunes, E; De Nucci, G; Dietrich, CP; Gambero, A; Giglio, JR; Landucci, EC; Marangoni, S; Nader, HB; Toyama, MH | 1 |
| Imaizumi, T; Kimura, H; Kobayashi, W; Liu, Q; Matsumiya, T; Nakagawa, H; Satoh, K; Yoshida, H | 1 |
| Jhamandas, K; McNaull, B; Quirion, R; Trang, T | 1 |
| Ajani, JA; Cao, L; Hoque, A; Liang, ZD; Lippman, SM; Swisher, S; Wu, TT; Xu, XC; Xu, Y; Zhang, H | 1 |
| Antunes, E; Camargo, EA; De Nucci, G; Desouza, IA; Franco-Penteado, CF; Lima, CS; Muscará, MN; Teixeira, SA | 1 |
| Fujisawa, N; Ihara, A; Nakajima, A; Takahashi, H; Wada, K; Yoneda, M | 1 |
| Leff, AR; Meliton, AY; Munoz, NM | 1 |
| Chung, HY; Chung, SW; Hayakawa, K; Kameda, T; Kizu, R; Tang, N; Toriba, A; Yu, BP | 1 |
| Berberich, N; Bihari, P; Khandoga, AG; Krombach, F; Lerchenberger, M; Rehberg, M; Reichel, CA; Zahler, S | 1 |
| Fomenko, IS; Panasyuk, NB; Sklyarov, AY | 1 |
| Kim, KA; Kim, SH; Lee, YA; Min, A; Nam, YH; Shin, MH; Song, KJ | 1 |
| Canetti, C; Chaves, MM; Coutinho-Silva, R; Marques-da-Silva, C; Monteiro, AP | 1 |
Other Studies
47 other study(ies) available for aa 861 and leukotriene b4
| Article | Year |
|---|---|
Platelet activating factor stimulates intracellular calcium transients in human neutrophils: involvement of endogenous 5-lipoxygenase products.
Topics: Arachidonate 5-Lipoxygenase; Benzoquinones; Calcium; Humans; Intracellular Fluid; Leukotriene B4; Lipoxygenase Inhibitors; Neutrophils; Platelet Activating Factor; Stimulation, Chemical | 1992 |
Postreceptor events associated with human neutrophil activation by interleukin-8.
Topics: Antibodies; Arachidonic Acid; Benzoquinones; Blotting, Western; Calcium; Cell Degranulation; Estrenes; Exocytosis; Humans; Inositol 1,4,5-Trisphosphate; Interleukin-8; Isoenzymes; Isomerism; Kinetics; Leukotriene B4; Lipoxygenase Inhibitors; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Pyrrolidinones; Receptors, Immunologic; Receptors, Interleukin-8A; Time Factors; Type C Phospholipases | 1992 |
Effects of a 5-lipoxygenase inhibitor, AA861, on lipoxygenase metabolism and superoxide anion generation by human polymorphonuclear leukocytes--potentiation of superoxide anion generation by LTB4.
Topics: Anions; Arachidonate Lipoxygenases; Arachidonic Acid; Aspirin; Benzoquinones; Complement C5a; Humans; In Vitro Techniques; Leukotriene B4; Lipoxygenase Inhibitors; Neutrophils; Superoxides | 1992 |
Effects of the new 5-lipoxygenase inhibitor E6080 on leukotriene release in vitro.
Topics: Animals; Arachidonate 5-Lipoxygenase; Basophils; Benzoquinones; Dose-Response Relationship, Drug; Guinea Pigs; Histamine Release; Humans; Hypersensitivity; In Vitro Techniques; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Lung; Male; Neutrophils; SRS-A; Thiazoles | 1992 |
Determination of plasma leukotrienes in antigen-induced bronchoconstrictive guinea pigs.
Topics: Administration, Inhalation; Anaphylaxis; Animals; Antigens; Benzoquinones; Bronchoconstriction; Chromatography, High Pressure Liquid; Guinea Pigs; Injections, Intravenous; Leukotriene B4; Lipoxygenase Inhibitors; Male; Pyrazoles; Rabbits; Radioimmunoassay; SRS-A; Thiazoles | 1991 |
Effects of leukotrienes on osteoblastic cell proliferation.
Topics: Animals; Benzoquinones; Bone Neoplasms; Cell Division; Cells, Cultured; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Humans; Indomethacin; Leukotriene B4; Lipoxygenase Inhibitors; Osteoblasts; Osteosarcoma; Rats; Rats, Inbred Strains; Serum Albumin, Bovine; Skull; Tumor Cells, Cultured | 1991 |
Effect of a novel 5-lipoxygenase inhibitor, E6080 on bronchospasm, airway cellular infiltration and leukotriene production in guinea pigs.
Topics: Acetophenones; Animals; Autacoids; Benzoquinones; Bronchial Spasm; Bronchoalveolar Lavage Fluid; Eosinophils; Guinea Pigs; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Male; Neutrophils; SRS-A; Tetrazoles; Thiazoles | 1991 |
Effect of 5-lipoxygenase inhibitor on canine pancreatic allotransplantation.
Topics: Animals; Benzoquinones; Blood Glucose; Dogs; Insulin; Leukotriene B4; Lipoxygenase Inhibitors; Pancreas Transplantation | 1991 |
Mechanism of acute gastrointestinal mucosal damage in endotoxic shock and the effect of Fragmin.
Topics: Acute Disease; Animals; Benzoquinones; Dogs; Gastric Mucosa; Hemorrhage; Heparin; Heparin, Low-Molecular-Weight; Intestinal Mucosa; Leukotriene B4; Lipoxygenase Inhibitors; Necrosis; Phospholipid Ethers; Platelet Activating Factor; Shock, Septic | 1990 |
Increased levels of immunoreactive leukotriene B4 in blister fluids of bullous pemphigoid patients and effects of a selective 5-lipoxygenase inhibitor on experimental skin lesions.
Topics: Animals; Benzoquinones; Chemotaxis, Leukocyte; Eosinophils; Fluorescent Antibody Technique; Guinea Pigs; Humans; Immunoglobulin G; Leukocyte Count; Leukotriene B4; Lipoxygenase Inhibitors; Male; Neutrophils; Pemphigoid, Bullous; Skin; SRS-A | 1990 |
Remarkable elevation of leukotriene B4 in rat skin after induction of UV photodermatitis.
Topics: Animals; Benzoquinones; Epoprostenol; Guinea Pigs; Leukotriene B4; Lipoxygenase Inhibitors; Male; Mice; Photosensitivity Disorders; Quinones; Rats; Skin; Species Specificity; Ultraviolet Rays | 1990 |
Leukotrienes in orthodontic tooth movement.
Topics: Animals; Benzoquinones; Dinoprostone; Drug Interactions; Female; Indomethacin; Leukotriene B4; Lipoxygenase Inhibitors; Male; Maxilla; Quinones; Rats; Rats, Inbred Strains; Tooth Movement Techniques | 1989 |
Release of leukotriene B4 from rat Kupffer cells.
Topics: Animals; Benzoquinones; Calcimycin; Cells, Cultured; Kupffer Cells; Leukotriene B4; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Quinones; Rats; Rats, Inbred Strains; Zymosan | 1989 |
Roles of endogenous leukotrienes and prostaglandins in the healing of gastric ulcers induced by acetic acid in rats.
Topics: Acetates; Acetic Acid; Animals; Benzoquinones; Gastric Mucosa; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Male; Prostaglandins; Quinones; Rats; Rats, Inbred Strains; Stomach Ulcer; Wound Healing | 1989 |
Reduction of myocardial infarct size in rats by a selective 5-lipoxygenase inhibitor (AA-861).
Topics: Animals; Benzoquinones; Leukotriene B4; Lipoxygenase Inhibitors; Male; Myocardial Infarction; Neutrophils; Quinones; Rats; Rats, Inbred Strains | 1987 |
Characterization of CGS 8515 as a selective 5-lipoxygenase inhibitor using in vitro and in vivo models.
Topics: Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Benzoquinones; Biotransformation; Blood Platelets; Calcimycin; Dexamethasone; Guinea Pigs; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Leukocytes; Leukotriene B4; Lipoxygenase Inhibitors; Male; Naphthoquinones; ortho-Aminobenzoates; Pleurisy; Quinones; Rats; Rats, Inbred Strains; Sheep | 1988 |
Role of leukotrienes in rat reversed passive Arthus pleurisy and the effect of AA-861, a 5-lipoxygenase inhibitor.
Topics: Animals; Arachidonate Lipoxygenases; Arthus Reaction; Benzoquinones; Biological Assay; Capillary Permeability; Chemotaxis, Leukocyte; Eosinophils; Female; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxygenase Inhibitors; Male; Mice; Monocytes; Neutrophils; Pleurisy; Pyrilamine; Quinones; Rabbits; Rats; SRS-A | 1986 |
Involvement of 5-lipoxygenase metabolites in ACTH-stimulated corticosteroidogenesis in rat adrenal glands.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Benzoquinones; Cyclic AMP; Dose-Response Relationship, Drug; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Indomethacin; Leukotriene B4; Leukotrienes; Lipoxygenase; Male; Quinones; Rats; Rats, Inbred Strains | 1985 |
Release of leukotrienes into the perfusate of calcium-ionophore stimulated rabbit lungs. Influence of 5-lipoxygenase inhibitors.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonate Lipoxygenases; Aspirin; Benzoquinones; Blood Pressure; Calcimycin; Dose-Response Relationship, Drug; Epoprostenol; Leukotriene B4; Lipoxygenase Inhibitors; Lung; Perfusion; Pulmonary Artery; Quinones; Rabbits; Secretory Rate; SRS-A | 1986 |
The role of leukotriene B4 in the genesis of oxygen toxicity in the lung.
Topics: Animals; Benzoquinones; Female; Inflammation; Leukotriene B4; Lung; Lung Diseases; Microsomes; NADPH-Ferrihemoprotein Reductase; Neutrophils; Oxygen; Quinones; Rats; Rats, Inbred Strains | 1986 |
A comparative study on the effects of inhibitors of the lipoxygenase pathway on neutrophil function. Inhibitory effects on neutrophil function may not be attributed to inhibition of the lipoxygenase pathway.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Benzoquinones; Calcimycin; Chemotaxis, Leukocyte; Epoprostenol; Humans; Hydroxides; Hydroxyl Radical; Leukotriene B4; Lipoxygenase Inhibitors; Masoprocol; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Quinones; Tetradecanoylphorbol Acetate; Umbelliferones | 1986 |
Effect of AA-861, a 5-lipoxygenase inhibitor, on leukotriene synthesis in human polymorphonuclear leukocytes and on cyclooxygenase and 12-lipoxygenase activities in human platelets.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Arachidonic Acid; Arachidonic Acids; Benzoquinones; Blood Platelets; Calcimycin; Diethylcarbamazine; Humans; Leukotriene B4; Lipoxygenase Inhibitors; Neutrophils; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Quinones; SRS-A | 1986 |
Inhibition of bovine lymphocyte response to phytohemagglutinin by a specific 5-lipoxygenase inhibitor.
Topics: Animals; Arachidonate Lipoxygenases; Benzoquinones; Cattle; Cells, Cultured; In Vitro Techniques; Interleukin-2; Leukotriene B4; Lipoxygenase Inhibitors; Lymphocyte Activation; Lymphocytes; Phytohemagglutinins; Quinones; SRS-A | 1987 |
Pharmacological profile of AA-861, a 5-lipoxygenase inhibitor.
Topics: Animals; Arachidonate Lipoxygenases; Asthma; Benzoquinones; Edema; Female; Guinea Pigs; Histamine Release; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxygenase Inhibitors; Lung; Macrophages; Male; Mast Cells; Passive Cutaneous Anaphylaxis; Pleurisy; Quinones; Rats; Rats, Inbred Strains; SRS-A | 1983 |
Neutrophil elastase inhibitor reduces asthmatic responses in allergic sheep.
Topics: Airway Resistance; Animals; Antigens; Asthma; Benzoquinones; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Calcimycin; Glycine; Heterocyclic Compounds; Leukocyte Elastase; Leukocytes; Leukotriene B4; Masoprocol; Methacholine Chloride; Pancreatic Elastase; Polycyclic Compounds; Sheep; Sulfonamides; Thromboxane B2 | 1995 |
LTC4/LTB4 alterations in rat forebrain ischemia and reperfusion and effects of AA-861, CV-3988.
Topics: Animals; Benzoquinones; Brain Edema; Brain Ischemia; Injections, Intraperitoneal; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; Male; Phospholipid Ethers; Platelet Activating Factor; Premedication; Prosencephalon; Rats; Rats, Wistar; Reperfusion Injury | 1994 |
Leukotrienes during rejection after canine pancreatic allotransplantation.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Benzoquinones; Dogs; Graft Rejection; Leukotriene B4; Lipoxygenase Inhibitors; Pancreas Transplantation; Thromboxane B2; Time Factors; Transplantation, Homologous | 1994 |
Lipoxygenase inhibitory activity of U-66,858 and its deacetylated metabolite U-68,244 in human whole blood.
Topics: Adult; Benzoquinones; Calcimycin; Female; Humans; Leukotriene B4; Lipoxygenase Inhibitors; Male; Naphthols; Thromboxane A2; Thromboxane B2 | 1994 |
Effects of inhibition of lipoxygenase and guanylate cyclase on human neutrophil responses to formyl peptide and granulocyte-macrophage colony-stimulating factor.
Topics: Aminoquinolines; Benzoquinones; Cyclic GMP; Drug Interactions; Granulocyte-Macrophage Colony-Stimulating Factor; Guanylate Cyclase; Humans; Leukotriene B4; Lipoxygenase Inhibitors; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Second Messenger Systems; SRS-A | 1993 |
Inhibition of 5-lipoxygenase promotes the regeneration of the liver after partial hepatectomy in normal and icteric rats.
Topics: Alanine Transaminase; Animals; Benzoquinones; Bilirubin; Bromodeoxyuridine; Cholestasis; Hepatectomy; Leukotriene B4; Lipoxygenase Inhibitors; Liver Regeneration; Male; Rats; Rats, Wistar | 1996 |
Involvement of leukotriene B4 in zymosan-induced rat pleurisy: inhibition of leukocyte infiltration by the 5-lipoxygenase inhibitor T-0757.
Topics: Amides; Animals; Benzoquinones; Guinea Pigs; Indomethacin; Leukocytes; Leukotriene B4; Lipoxygenase Inhibitors; Male; Pleurisy; Rats; Rats, Wistar; Zymosan | 1995 |
Acetylcholine and substance P stimulate bronchial epithelial cells to release eosinophil chemotactic activity.
Topics: Acetylcholine; Animals; Benzoquinones; Bronchi; Cattle; Cells, Cultured; Chemokines; Chemotaxis; Cycloheximide; Cyclooxygenase Inhibitors; Diethylcarbamazine; Eosinophils; Leukotriene B4; Lipoxygenase Inhibitors; Lung; Masoprocol; Substance P | 1998 |
Synergistic effect of type II phospholipase A2 and platelet-activating factor on Mac-1 surface expression and exocytosis of gelatinase granules in human neutrophils: evidence for the 5-lipoxygenase-dependent mechanism.
Topics: Arachidonate 5-Lipoxygenase; Benzoquinones; Calcium; Cytoplasmic Granules; Dose-Response Relationship, Drug; Drug Synergism; Exocytosis; Gelatinases; Humans; Leukotriene B4; Macrophage-1 Antigen; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor | 1998 |
Leukotriene metabolism by intrapulmonary vessels of newborn lambs: effect of platelet-activating factor.
Topics: Animals; Animals, Newborn; Arachidonic Acid; Benzoquinones; In Vitro Techniques; Leukotriene B4; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Lipoxygenase Inhibitors; Muscle, Smooth, Vascular; Platelet Activating Factor; Pulmonary Artery; Pulmonary Veins; Pyridinium Compounds; Sheep | 2001 |
Histamine stimulates alveolar macrophages to release neutrophil and monocyte chemotactic activity.
Topics: Acetates; Animals; Benzoquinones; Cattle; Cells, Cultured; Chemotactic Factors; Chromatography, Gel; Diethylcarbamazine; Histamine; Hot Temperature; Leukotriene B4; Macrophages, Alveolar; Masoprocol; Monocytes; Neutrophils; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serotonin; Trypsin | 2001 |
Human neutrophil migration in vitro induced by secretory phospholipases A2: a role for cell surface glycosaminoglycans.
Topics: Azepines; Benzoquinones; Cell Movement; Chemotaxis; Chondroitin Lyases; Flavobacterium; Glycosaminoglycans; Heparin; Heparin Lyase; Humans; In Vitro Techniques; Leukotriene B4; Lipoxygenase Inhibitors; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Aggregation Inhibitors; Polysaccharide-Lyases; Triazoles | 2002 |
Photodynamic therapy upregulates expression of Mac-1 and generation of leukotriene B(4) by human polymorphonuclear leukocytes.
Topics: Benzoquinones; CD11 Antigens; Flow Cytometry; Humans; Leukotriene B4; Lipoxygenase Inhibitors; Macrophage-1 Antigen; Neutrophils; Photochemotherapy; Photosensitizing Agents; Porphyrins; Up-Regulation | 2004 |
Involvement of spinal lipoxygenase metabolites in hyperalgesia and opioid tolerance.
Topics: Analgesics, Opioid; Animals; Benzoquinones; Dose-Response Relationship, Drug; Drug Tolerance; Flavanones; Formaldehyde; Hindlimb; Hyperalgesia; Injections, Spinal; Leukotriene B4; Leukotrienes; Lipid Peroxides; Lipoxygenase; Lipoxygenase Inhibitors; Male; Masoprocol; Morphine; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Spinal Cord; Time Factors | 2004 |
Increased 5-lipoxygenase expression and induction of apoptosis by its inhibitors in esophageal cancer: a potential target for prevention.
Topics: Adenocarcinoma; Apoptosis; Arachidonate 15-Lipoxygenase; Arachidonate 5-Lipoxygenase; Benzoquinones; Carcinoma, Squamous Cell; Cell Differentiation; Cell Survival; Esophageal Neoplasms; Esophagus; Fatty Alcohols; Female; Glycols; Humans; Immunoenzyme Techniques; Leukotriene B4; Lipoxygenase Inhibitors; Lymphatic Metastasis; Male; Middle Aged; Receptors, Leukotriene B4; Tumor Cells, Cultured | 2005 |
Acute pulmonary inflammation induced by exposure of the airways to staphylococcal enterotoxin type B in rats.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Benzoquinones; Bone Marrow; Bronchoalveolar Lavage Fluid; Celecoxib; Chemotaxis, Leukocyte; Cytokines; Dexamethasone; Dinoprostone; Dose-Response Relationship, Immunologic; Enterotoxins; Intubation, Intratracheal; Leukocyte Count; Leukotriene B4; Lipoxygenase Inhibitors; Male; Neutrophils; Pneumonia, Staphylococcal; Pyrazoles; Rats; Rats, Wistar; Sulfonamides; Time Factors | 2006 |
Blockade of leukotriene B4 signaling pathway induces apoptosis and suppresses cell proliferation in colon cancer.
Topics: Apoptosis; Benzoquinones; Caco-2 Cells; Cell Proliferation; Cell Survival; Colonic Neoplasms; Extracellular Signal-Regulated MAP Kinases; Fatty Alcohols; Glycols; Humans; Leukotriene B4; Lipoxygenase Inhibitors; Receptors, Leukotriene B4; RNA Interference; Signal Transduction | 2007 |
Blockade of avidity and focal clustering of beta 2-integrin by cysteinyl leukotriene antagonism attenuates eosinophil adhesion.
Topics: Acetates; Arachidonate 5-Lipoxygenase; Benzoquinones; CD11b Antigen; CD18 Antigens; Cell Adhesion; Cells, Cultured; Chemokine CCL11; Cyclopropanes; Cysteine; Eosinophils; Humans; Inflammation Mediators; Interleukin-5; Leukotriene Antagonists; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Quinolines; Sulfides | 2007 |
Activation of 5-lipoxygenase and NF-kappa B in the action of acenaphthenequinone by modulation of oxidative stress.
Topics: Acenaphthenes; Acetylcysteine; Antioxidants; Arachidonate 15-Lipoxygenase; Benzoquinones; Biotransformation; Blotting, Western; Cell Line, Tumor; Enzyme Activation; Genes, Reporter; Humans; Immunoenzyme Techniques; Indicators and Reagents; Inflammation; Leukotriene B4; Luciferases; NF-kappa B; Oxidative Stress; Up-Regulation | 2008 |
Ccl2 and Ccl3 mediate neutrophil recruitment via induction of protein synthesis and generation of lipid mediators.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Benzoquinones; Cells, Cultured; Chemokine CCL2; Chemokine CCL3; Chemotaxis, Leukocyte; Dactinomycin; Disease Models, Animal; Indoles; Indomethacin; Leukotriene B4; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred BALB C; Neutrophil Infiltration; Protein Biosynthesis; Random Allocation; Sensitivity and Specificity | 2009 |
Role of nitric oxide-synthase and cyclooxygenase/lipooxygenase systems in development of experimental ulcerative colitis.
Topics: Acetic Acid; Animals; Antioxidants; Arachidonate 5-Lipoxygenase; Arginine; Benzoquinones; Celecoxib; Colitis, Ulcerative; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Female; Guanidines; Indomethacin; Intestine, Large; Leukotriene B4; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Pyrazoles; Rats; Sulfonamides | 2011 |
Leukotriene B(4) receptors BLT1 and BLT2 are involved in interleukin-8 production in human neutrophils induced by Trichomonas vaginalis-derived secretory products.
Topics: Benzoquinones; Endopeptidase K; Fatty Alcohols; Glycols; Hot Temperature; Humans; Interleukin-8; Leukotriene Antagonists; Leukotriene B4; Lipase; Lipoxygenase Inhibitors; Neutrophil Activation; Neutrophils; Piperazines; Receptors, Leukotriene B4; Tetrazoles; Thiazoles; Trichomonas Infections; Trichomonas vaginalis | 2012 |
Leukotriene B4 modulates P2X7 receptor-mediated Leishmania amazonensis elimination in murine macrophages.
Topics: Animals; Arachidonate 5-Lipoxygenase; Benzopyrans; Benzoquinones; Calcium Ionophores; Carboxylic Acids; Female; Ionomycin; Leishmania; Leishmaniasis; Leukotriene B4; Lipoxygenase Inhibitors; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Mice, Knockout; Receptors, Purinergic P2X7 | 2014 |