aa 861 and indomethacin
aa 861 has been researched along with indomethacin in 66 studies
Research
Studies (66)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (27.27) | 18.7374 |
| 1990's | 35 (53.03) | 18.2507 |
| 2000's | 9 (13.64) | 29.6817 |
| 2010's | 4 (6.06) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Cook, DA; Tsuji, T | 1 |
| Alexander, SP; Dickenson, JM; Hill, SJ; White, TE | 1 |
| Ikenoue, T; Lee, HC; Mibe, M; Miyakawa, I; Mori, N; Ohtsuka, T | 1 |
| Kanamaru, K; Matsumoto, T; Murata, Y; Sugiyama, Y | 1 |
| Houzawa, S; Kurose, I; Miura, S; Nagata, H; Serizawa, H; Suematsu, M; Suzuki, M; Tanaka, S; Tsuchiya, M | 1 |
| Dziak, R; Ren, W | 1 |
| Ebbesen, MA; Gibel, L; Goodwin, JS; Harford, AM; Shopp, GM; Smith, AY; Sterling, WA | 1 |
| Henson, PM; Leslie, CC; Lew, DB; Riches, DW | 1 |
| Isogai, T; Satake, T; Suzuki, K; Takagi, K; Taki, F | 1 |
| Kurachi, Y; Nakajima, T; Sugimoto, T | 1 |
| Kobayashi, T; Yamane, K | 1 |
| Danno, K; Horio, T; Ikai, K; Imamura, S; Toda, K | 1 |
| Kawada, N; Kobayashi, K; Mizoguchi, Y; Morisawa, S; Yamamoto, S | 1 |
| Cook, DA; Jancar, S; Schulz, R | 1 |
| Makino, S | 1 |
| Kamada, T; Kawano, S; Sato, N; Tsuji, S | 1 |
| Adachi, H; Aoki, E; Honda, T; Noguchi, M; Onishi, S; Sato, S; Torizuka, K | 1 |
| Walker, JR; Woodhouse, SA | 1 |
| Hoshi, A; Kitamura, S; Kobayashi, J | 1 |
| Fujimoto, K; Itoh, H; Kanamaru, K; Kubo, Y; Waga, S | 1 |
| Behrens, TW; Goodwin, JS; Lianos, EA; Lum, LG | 1 |
| Okamura, T; Toda, N | 1 |
| Hirota, K; Ikegami, H; Miyake, A; Nishizaki, T; Tanizawa, O; Tasaka, K | 1 |
| Dziak, R; Mohammed, AH; Tatakis, DN | 1 |
| Hayashi, N; Kamada, T; Kawano, S; Matsunaga, T; Ogihara, T; Sakura, H; Sato, N; Tanimura, H; Tsuji, S; Tsujii, M | 1 |
| Jolly, SR; Travis, J; Van Inwegen, RG | 1 |
| Colombo, C; Dotson, R; Ghai, G; Kimble, EF; Ku, EC; Lee, WH; Oglesby, TD; Raychaudhuri, A; Wasley, JW | 1 |
| Ida, E; Onoue, K; Sakata, A; Tominaga, M; Yamasaki, H | 1 |
| Hirai, A; Saito, H; Tahara, K; Tamura, Y; Terano, T; Yoshida, S | 1 |
| Kato, R; Uzumaki, H; Yamamoto, S | 1 |
| Goldin, E; Harel, S; Magal, E; Yavin, E | 1 |
| Toda, N | 1 |
| Kato, K; Murota, S | 1 |
| Aizu, E; Kato, R; Nakadate, T; Yamamoto, S | 1 |
| Moriya, Y; Teshigawara, H | 1 |
| Fujimoto, R; Hata, F; Kubo, T; Nagao, T; Nishio, H; Takeuchi, T | 1 |
| Kugiyama, K; Murohara, T; Ohgushi, M; Sugiyama, S; Yasue, H | 1 |
| Hamada, K; Inoue, K; Kimura, K; Shibata, Y; Ueda, F | 1 |
| Iwama, T; Nagai, H; Sakurai, T; Yamaguchi, S | 1 |
| Kasayama, S; Kishimoto, T; Koga, M; Kouhara, H; Sato, B; Sumitani, S; Wada, K | 1 |
| Furukawa, K; Kobayashi, T; Onda, M | 1 |
| Chang, SW; Chen, CR; Voelkel, NF | 1 |
| Horiba, M; Kohno, S; Nabe, T; Ohata, K; Tsuzuike, N; Yamamura, H | 1 |
| Arakawa, T; Fukuda, T; Higuchi, K; Kobayashi, K; Nakamura, H | 1 |
| Semb, AG; Vaage, J; Valen, G | 1 |
| Guth, E; Guth, PH; LeDuc, LE; Reedy, T; Su, KC | 1 |
| Huang, YC; Kennedy, TP; Piantadosi, CA; Su, YF; Watkins, WD; Whorton, AR | 1 |
| Fryer, AD; Jacoby, DB; Kahn, RM; Okanlami, OA | 1 |
| Higuchi, K; Kominami, S; Takemori, S; Yamazaki, T | 1 |
| Matsuzaki, T; Noguchi, K; Ojiri, Y; Sakanashi, M; Shiroma, N | 1 |
| Hata, F; Nishio, H; Takeuchi, T; Yagasaki, O | 1 |
| Kikuchi, M; Naito, K; Tsuzurahara, K | 1 |
| Sato, F; Satoh, H; Szabo, S; Takami, K | 1 |
| Kohno, S; Miyake, I; Nabe, T; Yamamura, H | 1 |
| Bedouch, P; Bessard, G; Chavanon, O; Cracowski, JL; Devillier, P; Stanke-Labesque, F | 1 |
| Cho, W; Fujimura, M; Kim, KP; Kita, T; Kurashima, K; Leff, AR; Munoz, NM; Myou, S; Nakao, S; Nonomura, A; Sano, H; Shioya, T; Zhu, X | 1 |
| Loscalzo, J; Walker, JL; Zhang, YY | 1 |
| Arruda, VA; Bon, C; de Araújo, AL; de Araújo, PM; de Queiroz Guimarães, A; Hyslop, S | 1 |
| Chu, SJ; Feng, NH; Lin, HI; Wang, D | 1 |
| Li, GM; Liang, CL; Wang, ZJ; Yin, M; Yu, CY | 1 |
| Antunes, E; Desouza, IA; Ferreira, T; Macedo, ML; Mariano, NS; Mello, GC | 1 |
| Berberich, N; Bihari, P; Khandoga, AG; Krombach, F; Lerchenberger, M; Rehberg, M; Reichel, CA; Zahler, S | 1 |
| Cortadellas, N; Ferrer, R; Moretó, M; Roig-Pérez, S | 1 |
| Berthiaume, M; Corriveau, S; Pasquier, JC; Rousseau, E | 1 |
| Fomenko, IS; Panasyuk, NB; Sklyarov, AY | 1 |
Trials
1 trial(s) available for aa 861 and indomethacin
| Article | Year |
|---|---|
Lipoxygenase and cyclooxygenase inhibitors reveal a complementary role of arachidonic acid derivatives in pregnant human myometrium.
Topics: Adult; Benzoquinones; Biopsy; Blotting, Western; Cyclooxygenase Inhibitors; Female; Flavanones; Humans; Indomethacin; Isoenzymes; Lipoxygenase; Lipoxygenase Inhibitors; Myometrium; Pregnancy; Prostaglandin-Endoperoxide Synthases; Uterine Contraction | 2010 |
Other Studies
65 other study(ies) available for aa 861 and indomethacin
| Article | Year |
|---|---|
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Biphasic response to substance P in canine basilar arteries.
Topics: Animals; Basilar Artery; Benzoquinones; Dogs; Endothelium, Vascular; Female; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Male; Methacrylates; Nimodipine; Oxyhemoglobins; Saponins; Substance P; Thromboxane-A Synthase; Vasoconstriction; Vasodilation | 1992 |
Adenosine A1-receptor stimulation of inositol phospholipid hydrolysis and calcium mobilisation in DDT1 MF-2 cells.
Topics: 2-Chloroadenosine; Adenosine; Animals; Benzoquinones; Calcium; Cell Line; Cricetinae; Hydrolysis; Indomethacin; Lipoxygenase Inhibitors; Male; Muscle, Smooth; Phosphatidylinositols; Receptors, Purinergic | 1992 |
The effects of a 5-lipoxygenase inhibitor, AA-861, on PGI2-like substance production in guinea-pig lungs.
Topics: Animals; Benzoquinones; Dose-Response Relationship, Drug; Epoprostenol; Ethanol; Guinea Pigs; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Lung; Platelet Aggregation | 1992 |
Endothelium-derived relaxation of the pregnant and nonpregnant canine uterine artery.
Topics: Acetylcholine; Animals; Benzoquinones; Calcimycin; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Evaluation Studies as Topic; Female; Indomethacin; Lipoxygenase Inhibitors; Masoprocol; Nitric Oxide; Pregnancy; Pregnancy, Animal; Uterus; Vasoconstriction | 1992 |
Microcirculatory disturbance in indomethacin-induced intestinal ulcer.
Topics: Animals; Benzoquinones; Chromones; Fluorescein-5-isothiocyanate; Fluoresceins; Indomethacin; Intestinal Diseases; Intestinal Mucosa; Leukocyte Count; Lipoxygenase Inhibitors; Male; Microcirculation; Neutrophils; Peroxidase; Rats; Rats, Inbred Strains; Serum Albumin, Bovine; SRS-A; Ulcer | 1991 |
Effects of leukotrienes on osteoblastic cell proliferation.
Topics: Animals; Benzoquinones; Bone Neoplasms; Cell Division; Cells, Cultured; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Humans; Indomethacin; Leukotriene B4; Lipoxygenase Inhibitors; Osteoblasts; Osteosarcoma; Rats; Rats, Inbred Strains; Serum Albumin, Bovine; Skull; Tumor Cells, Cultured | 1991 |
Murine thymocyte lysis by inhibitors of arachidonic acid metabolism.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adrenal Cortex Hormones; Animals; Arachidonic Acid; Arachidonic Acids; Benzoquinones; Caffeic Acids; Cells, Cultured; Dexamethasone; Dinoprostone; Indomethacin; Lipoxygenase Inhibitors; Masoprocol; Mice; Mice, Inbred C57BL; Spleen; Thymus Gland | 1991 |
Role of endogenously derived leukotrienes in the regulation of lysosomal enzyme expression in macrophages exposed to beta 1,3-glucan.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Benzoquinones; beta-Glucans; beta-N-Acetylhexosaminidases; Cyclooxygenase Inhibitors; Dinoprostone; Glucans; Indomethacin; Leukotrienes; Lipoxygenase Inhibitors; Lysosomes; Macrophages; Male; Mice; Mice, Inbred BALB C; Phospholipases A; Phospholipases A2; SRS-A | 1991 |
Inhibitory effect of dietary administration of eicosapentaenoic acid on the contractions of guinea-pig tracheal smooth muscle induced by leukotriene C4 and D4.
Topics: Animals; Benzoquinones; Body Weight; Chromatography, High Pressure Liquid; Diet; Eicosapentaenoic Acid; Fatty Acids; Guinea Pigs; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Lung; Male; Muscle Contraction; Muscle, Smooth; Phospholipids; SRS-A; Trachea | 1991 |
Platelet-activating factor activates cardiac GK via arachidonic acid metabolites.
Topics: Animals; Arachidonic Acids; Benzoquinones; Cells, Cultured; Flavanones; Flavonoids; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; Heart; Heart Atria; Indomethacin; Lipoxygenase Inhibitors; Masoprocol; Membrane Potentials; Myocardium; Platelet Activating Factor; Potassium Channels; Virulence Factors, Bordetella | 1991 |
Endogenous AA metabolites and their possible role in tracheal smooth muscle tone in guinea pigs.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Benzoquinones; Chromones; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Methacrylates; Muscle Contraction; Muscle, Smooth; Quinones; SRS-A; Thromboxane-A Synthase; Trachea | 1990 |
Ultraviolet radiation suppresses mouse-ear edema induced by topical application of arachidonic acid.
Topics: Administration, Topical; Animals; Arachidonic Acids; Benzoquinones; Cell Count; Disease Models, Animal; Ear; Edema; Indomethacin; Lipoxygenase Inhibitors; Mast Cells; Mice; PUVA Therapy; Quinones; Skin Diseases; Ultraviolet Rays; Ultraviolet Therapy | 1990 |
Arachidonic acid metabolites in carbon tetrachloride-induced liver injury.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Benzoquinones; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Indomethacin; Leukotrienes; Lipoxygenase Inhibitors; Liver; Male; Prostaglandins; Quinones; Rats; Rats, Inbred Strains | 1990 |
Cerebral arteries can generate 5- and 15-hydroxyeicosatetraenoic acid from arachidonic acid.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Benzoquinones; Cattle; Cerebral Arteries; Chromatography, High Pressure Liquid; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Muscle, Smooth, Vascular; Quinones; Radioimmunoassay | 1990 |
[Eicosanoids in bronchial asthma].
Topics: Acrylates; Arachidonic Acids; Asthma; Benzoquinones; Bronchoalveolar Lavage Fluid; Chromones; Cyclooxygenase Inhibitors; Humans; Indomethacin; Leukocytes; Lipoxygenase Inhibitors; Lung; Macrophages; Methacrylates; Quinones; Thromboxane-A Synthase | 1990 |
Mucosal blood flow stasis and hypoxemia as the pathogenesis of acute gastric mucosal injury: role of endogenous leukotrienes and prostaglandins.
Topics: Animals; Benzoquinones; Ethanol; Gastric Mucosa; Indomethacin; Leukotrienes; Lipoxygenase Inhibitors; Male; Microcirculation; Premedication; Prostaglandins; Rats; Rats, Inbred Strains | 1990 |
Effect of AA861, a 5-lipoxygenase inhibitor, on amylase secretion from rat pancreatic acini.
Topics: Amylases; Animals; Arachidonate Lipoxygenases; Benzoquinones; Bombesin; Calcimycin; Carbachol; Cholecystokinin; In Vitro Techniques; Indomethacin; Kinetics; Lipoxygenase Inhibitors; Male; Pancreas; Quinones; Rats; Rats, Inbred Strains; Sincalide; Tetradecanoylphorbol Acetate | 1988 |
Arachidonic acid products and the thoracic accumulation of neutrophils and platelets following i.v. antigen challenge of sensitised guinea-pig.
Topics: Animals; Antigens; Arachidonic Acids; Benzoquinones; Blood Platelets; Guinea Pigs; Immunization; Indomethacin; Leukotrienes; Lipoxygenase Inhibitors; Lung; Neutrophils; Pyrazoles; Quinones | 1989 |
[Mechanisms of bronchoconstriction induced by anaphylaxis in sensitized guinea pigs].
Topics: Anaphylaxis; Animals; Benzoquinones; Bronchi; Guinea Pigs; Histamine Antagonists; Indomethacin; Leukotrienes; Lipoxygenase Inhibitors; Muscle Contraction; Muscle, Smooth; Prostaglandins; Quinones; Thromboxanes | 1989 |
Endothelium-dependent relaxation of human basilar arteries.
Topics: Acetylcholine; Adult; Aged; Basilar Artery; Benzoquinones; Calcimycin; Child; Child, Preschool; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Humans; Indomethacin; Lipoxygenase Inhibitors; Male; Middle Aged; Mixed Function Oxygenases; Muscle Contraction; Muscle Relaxation; Pyridines; Quinones | 1989 |
Lipoxygenase inhibitors enhance the proliferation of human B cells.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adjuvants, Immunologic; Adult; B-Lymphocytes; Benzoquinones; Cell Differentiation; Child; Cyclooxygenase Inhibitors; Dose-Response Relationship, Immunologic; Humans; Immunoglobulins; Indomethacin; Interleukin-4; Interleukins; Kinetics; Lipoxygenase Inhibitors; Lymphocyte Activation; Masoprocol; Palatine Tonsil; Pyrazoles; Quinones; Staphylococcal Protein A | 1989 |
Different involvement of endothelium-derived relaxing factor and prostacyclin in vasodilator response to bradykinin in isolated dog blood vessels.
Topics: Animals; Benzoquinones; Bradykinin; Coronary Vessels; Dogs; Endothelium, Vascular; Epoprostenol; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Methylene Blue; Muscle, Smooth, Vascular; Nitric Oxide; Papaverine; Quinones; Vasodilation | 1989 |
Mechanism of release of beta-endorphin from rat pituitary cells. Role of lipoxygenase products of arachidonic acid.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Benzoquinones; beta-Endorphin; Biomechanical Phenomena; Female; Indomethacin; Leukotrienes; Lipoxygenase; Lipoxygenase Inhibitors; Pituitary Gland; Quinones; Rats; Rats, Inbred Strains | 1989 |
Leukotrienes in orthodontic tooth movement.
Topics: Animals; Benzoquinones; Dinoprostone; Drug Interactions; Female; Indomethacin; Leukotriene B4; Lipoxygenase Inhibitors; Male; Maxilla; Quinones; Rats; Rats, Inbred Strains; Tooth Movement Techniques | 1989 |
[Roles of intrinsic prostaglandins and leukotrienes in gastric mucosal damage].
Topics: Animals; Benzoquinones; Ethanol; Gastric Mucosa; Indomethacin; Leukotrienes; Male; Prostaglandins; Quinones; Rats; Rats, Inbred Strains | 1989 |
Effects of 5-lipoxygenase inhibition on cardiac anaphylaxis in isolated guinea pig hearts.
Topics: Acetophenones; Anaphylaxis; Animals; Arachidonate Lipoxygenases; Benzoquinones; Benzyl Compounds; Blood Pressure; Cardiomyopathies; Chromones; Coronary Circulation; Guinea Pigs; Heart; Hydroxamic Acids; Hydroxyquinolines; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Male; Myocardium; Quinolines; Quinones; SRS-A; Tetrazoles | 1989 |
Characterization of CGS 8515 as a selective 5-lipoxygenase inhibitor using in vitro and in vivo models.
Topics: Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Benzoquinones; Biotransformation; Blood Platelets; Calcimycin; Dexamethasone; Guinea Pigs; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Leukocytes; Leukotriene B4; Lipoxygenase Inhibitors; Male; Naphthoquinones; ortho-Aminobenzoates; Pleurisy; Quinones; Rats; Rats, Inbred Strains; Sheep | 1988 |
Arachidonic acid release is closely related to the Fc gamma receptor-mediated superoxide generation in macrophages.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetophenones; Animals; Arachidonic Acid; Arachidonic Acids; Benzoquinones; Glucose; Guinea Pigs; In Vitro Techniques; Indomethacin; Isoquinolines; Macrophages; Phospholipases A; Phospholipases A2; Piperazines; Protein Kinase C; Quinones; Receptors, Fc; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Involvement of 5-lipoxygenase metabolites in ACTH-stimulated corticosteroidogenesis in rat adrenal glands.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Benzoquinones; Cyclic AMP; Dose-Response Relationship, Drug; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Indomethacin; Leukotriene B4; Leukotrienes; Lipoxygenase; Male; Quinones; Rats; Rats, Inbred Strains | 1985 |
Effects of lipoxygenase and cyclooxygenase inhibitors on the induction of ornithine decarboxylase by 12-O-tetradecanoylphorbol-13-acetate and isoproterenol in mouse tissues in vivo.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Benzoquinones; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Induction; Female; Indomethacin; Isoproterenol; Kidney; Lipoxygenase Inhibitors; Liver; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Phorbols; Pyrazoles; Quinones; Spleen; Tetradecanoylphorbol Acetate | 1986 |
Acute uteroplacental ischemic embryo: lactic acid accumulation and prostaglandin production in the fetal rat brain.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Benzoquinones; Brain; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Female; Indomethacin; Ischemia; Lactates; Lactic Acid; Lipoxygenase Inhibitors; Masoprocol; Placenta; Pregnancy; Prostaglandins; Prostaglandins E; Prostaglandins F; Pyrazoles; Quinones; Rats; Uterus | 1988 |
Mechanisms of histamine-induced relaxation in isolated monkey and dog coronary arteries.
Topics: Animals; Benzoquinones; Chlorpheniramine; Cimetidine; Coronary Vessels; Dogs; Female; Histamine; Indomethacin; Macaca; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Quinones; Vasodilation | 1986 |
Lipoxygenase specific inhibitors inhibit murine lymphocyte reactivity to Con A by reducing IL-2 production and its action.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Benzoquinones; Caffeic Acids; Cells, Cultured; Cinnamates; Concanavalin A; Female; Indomethacin; Interleukin-2; Lipoxygenase Inhibitors; Lymphocyte Activation; Lymphocytes; Mice; Mice, Inbred BALB C; Quinones | 1985 |
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced increase in vascular permeability in mouse skin by lipoxygenase inhibitors.
Topics: Animals; Benzoquinones; Capillary Permeability; Catechols; Female; Indomethacin; Lipoxygenase; Lipoxygenase Inhibitors; Masoprocol; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Phorbols; Prostaglandin-Endoperoxide Synthases; Quercetin; Quinones; Skin; Tetradecanoylphorbol Acetate | 1985 |
The role of leukotriene C4 in biphasic release of histamine from mouse mastocytoma cell line (P-815).
Topics: Animals; Benzoquinones; Dose-Response Relationship, Drug; Histamine Release; Indomethacin; Leukotriene C4; Leukotrienes; Mast-Cell Sarcoma; Mice; p-Methoxy-N-methylphenethylamine; Phospholipases A; Substance P; Tumor Cells, Cultured | 1994 |
Ca(2+)-independent fusion of secretory granules with phospholipase A2-treated plasma membranes in vitro.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Albumins; Amylases; Animals; Arachidonic Acid; Benzoquinones; Calcium; Cell Membrane; Cytoplasmic Granules; Egtazic Acid; Exocytosis; Fatty Acids; Indomethacin; Lipoxygenase Inhibitors; Lysophosphatidylcholines; Male; Membrane Fusion; Microscopy, Electron; Parotid Gland; Phospholipases A; Phospholipases A2; Quinacrine; Rats; Rats, Wistar | 1995 |
Activated human polymorphonuclear leukocytes elicit endothelium-dependent contraction in isolated pig coronary arteries.
Topics: Animals; Arginine; Benzoquinones; Coronary Vessels; Endothelium, Vascular; Free Radicals; Humans; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Luminescent Measurements; Muscle, Smooth, Vascular; Neutrophils; Nitric Oxide; omega-N-Methylarginine; Oxygen Consumption; Superoxide Dismutase; Swine; Zymosan | 1993 |
Effect of anti-inflammatory agent etodolac on antigen-induced contractions of the trachea and lung parenchyma of guinea pigs.
Topics: Animals; Asthma; Benzoquinones; Disease Models, Animal; Etodolac; Guinea Pigs; Immunization, Passive; Indomethacin; Isoantigens; Lipoxygenase Inhibitors; Lung; Methacrylates; Muscle Contraction; Muscle, Smooth; Rabbits; Serum Albumin, Bovine; Thromboxane A2; Trachea | 1994 |
Pharmacological studies of platelet-activating factor (PAF)-induced augmentation of response to histamine in guinea-pigs.
Topics: Animals; Benzoquinones; Bridged Bicyclo Compounds; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Capillary Permeability; Chromones; Drug Interactions; Fatty Acids, Monounsaturated; Guinea Pigs; Histamine; Indomethacin; Leukocyte Count; Leukotriene Antagonists; Lipoxygenase Inhibitors; Male; Methacrylates; Phospholipid Ethers; Platelet Activating Factor; Pressure; Respiratory Physiological Phenomena; Respiratory System; Thromboxane A2 | 1994 |
Unsaturated fatty acids are required for continuous proliferation of transformed androgen-dependent cells by fibroblast growth factor family proteins.
Topics: Animals; Arachidonic Acids; Benzoquinones; Cell Adhesion; Cell Cycle; Cell Division; Culture Media, Serum-Free; Fatty Acids; Fatty Acids, Monounsaturated; Fibroblast Growth Factor 2; Indomethacin; Linoleic Acid; Linoleic Acids; Mammary Neoplasms, Animal; Mice; Neoplasms, Hormone-Dependent; Oleic Acid; Oleic Acids; Testosterone; Tumor Cells, Cultured | 1994 |
[The effect of arachidonic acid metabolite inhibitors on liver injury in endotoxin shock, with special reference to the role of polymorphonuclear leukocytes (PMNs)].
Topics: Animals; Arachidonic Acid; Benzoquinones; Hydrocortisone; Indomethacin; Liver Diseases; Male; Neutrophils; Phagocytosis; Rats; Rats, Wistar; Shock, Septic | 1994 |
Platelet-activating factor potentiates protamine-induced lung edema. Role of eicosanoids.
Topics: Animals; Arachidonic Acid; Benzoquinones; Constriction, Pathologic; Drug Synergism; Indomethacin; Leukotriene C4; Lipoxygenase Inhibitors; Male; Organ Size; Platelet Activating Factor; Premedication; Prostaglandins F; Protamines; Pulmonary Circulation; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Thromboxane B2; Vascular Resistance | 1994 |
Important role of peptide leukotrienes (p-LTs) in the resting tonus of isolated human bronchi.
Topics: Animals; Benzoquinones; Bronchi; Guinea Pigs; Humans; In Vitro Techniques; Indicators and Reagents; Indomethacin; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Lung; Male; Muscle Tonus; Muscle, Smooth; Radioimmunoassay; Thiazoles | 1993 |
Role of leukotrienes in indomethacin-induced mucosal damage in rats.
Topics: Animals; Benzoquinones; Gastric Mucosa; Indomethacin; Leukotrienes; Lipoxygenase Inhibitors; Male; Rats; Rats, Wistar; Regional Blood Flow; SRS-A; Thiadiazoles | 1993 |
Inhibition of lipoxygenase and cyclooxygenase augments cardiac injury by H2O2.
Topics: Animals; Benzeneacetamides; Benzoquinones; Coronary Circulation; Cyclooxygenase Inhibitors; Diethylcarbamazine; Free Radical Scavengers; Heart; Heart Ventricles; Hydrogen Peroxide; Hydroxamic Acids; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Male; Myocardial Reperfusion Injury; Pressure; Rats; Rats, Wistar; Reactive Oxygen Species; Thiourea | 1993 |
Effects of cyclooxygenase and lipoxygenase inhibition on eicosanoids and healing of acetic acid colitis in rats.
Topics: Acetates; Acetic Acid; Analysis of Variance; Animals; Benzoquinones; Colitis; Colon; Cyclooxygenase Inhibitors; Disease Models, Animal; Drug Evaluation, Preclinical; Eicosanoids; Indomethacin; Lipoxygenase Inhibitors; Male; Rats; Rats, Sprague-Dawley; Wound Healing | 1993 |
Protection against platelet-activating factor-induced injury by interferon inducer in perfused rabbit lung.
Topics: Animals; Arachidonic Acids; Benzoquinones; Blood Pressure; Bronchoconstriction; Humans; Hypertension, Pulmonary; In Vitro Techniques; Indicators and Reagents; Indomethacin; Interferon Inducers; Interferon Type I; Lipoxygenase Inhibitors; Lung Diseases; Male; Microcirculation; Platelet Activating Factor; Poly I-C; Pulmonary Edema; Rabbits; Recombinant Proteins; Vascular Resistance | 1993 |
Viral infection induces dependence of neuronal M2 muscarinic receptors on cyclooxygenase in guinea pig lung.
Topics: Animals; Antibodies, Viral; Benzoquinones; Cells, Cultured; Cyclooxygenase Inhibitors; Electric Stimulation; Gallamine Triethiodide; Guinea Pigs; Heart Rate; Indans; Indomethacin; Inflammation; Lung; Lung Diseases; Macaca mulatta; Neurons; Ozone; Parainfluenza Virus 1, Human; Paramyxoviridae Infections; Pilocarpine; Prostaglandin-Endoperoxide Synthases; Receptor, Muscarinic M2; Receptors, Muscarinic; Vagus Nerve | 1996 |
15-lipoxygenase metabolite(s) of arachidonic acid mediates adrenocorticotropin action in bovine adrenal steroidogenesis.
Topics: Animals; Arachidonate 15-Lipoxygenase; Arachidonic Acids; Benzoquinones; Bucladesine; Cattle; Cells, Cultured; Cosyntropin; Cyclic AMP; Dihydrotestosterone; Enzyme Inhibitors; Indomethacin; Isoquinolines; Kinetics; Leukotrienes; Lipid Peroxides; Lipoxygenase Inhibitors; Masoprocol; Pregnenolone; Sulfonamides; Tetrahydronaphthalenes; Zona Fasciculata; Zona Reticularis | 1996 |
Involvement of nitric oxide and eicosanoids in platelet-activating factor-induced haemodynamic and haematological effects in dogs.
Topics: Animals; Benzoquinones; Biphenyl Compounds; Cell Count; Cyclooxygenase Inhibitors; Dogs; Dose-Response Relationship, Drug; Eicosanoids; Female; Heptanoic Acids; Hypotension; Indomethacin; Isoquinolines; Lipoxygenase Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prostaglandin Antagonists; Pyridinium Compounds; Tetrahydroisoquinolines; Vascular Resistance | 1996 |
Ca(2+)-independent fusion of synaptic vesicles with phospholipase A2-treated presynaptic membranes in vitro.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetylcholine; Albumins; Animals; Arachidonic Acid; Benzoquinones; Brain; Calcium; Egtazic Acid; Exocytosis; In Vitro Techniques; Indomethacin; Male; Membrane Fusion; Neurotransmitter Agents; Phospholipases A; Phospholipases A2; Quinacrine; Rats; Rats, Wistar; Swine; Synaptic Membranes; Synaptic Vesicles | 1996 |
Involvement of leukotriene B4 in zymosan-induced rat pleurisy: inhibition of leukocyte infiltration by the 5-lipoxygenase inhibitor T-0757.
Topics: Amides; Animals; Benzoquinones; Guinea Pigs; Indomethacin; Leukocytes; Leukotriene B4; Lipoxygenase Inhibitors; Male; Pleurisy; Rats; Rats, Wistar; Zymosan | 1995 |
New ulcerative colitis model induced by sulfhydryl blockers in rats and the effects of antiinflammatory drugs on the colitis.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Benzoquinones; Colitis, Ulcerative; Colon; Dexamethasone; Diarrhea; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Ethylmaleimide; Gastrointestinal Hemorrhage; Indomethacin; Intestinal Mucosa; Iodoacetamide; Lipoxygenase Inhibitors; Male; Organ Size; Peroxidase; Rats; Rats, Sprague-Dawley; Sulfhydryl Reagents | 1997 |
Reproducible biphasic cutaneous edema induced by topical and repeated application of antigen in sensitized mice.
Topics: Animals; Antigens; Benzoquinones; Cyclooxygenase Inhibitors; Dermatitis, Allergic Contact; Histamine H1 Antagonists; Indomethacin; Lipoxygenase Inhibitors; Male; Mice; Ovalbumin; Pyrilamine; Reproducibility of Results | 2000 |
Angiotensin II-induced contractions in human internal mammary artery: effects of cyclooxygenase and lipoxygenase inhibition.
Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Angiotensin II; Benzoquinones; Biphenyl Compounds; Cyclooxygenase Inhibitors; Depression, Chemical; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavanones; Flavonoids; Heptanoic Acids; Humans; Imidazoles; In Vitro Techniques; Indomethacin; Leukotrienes; Lipoxygenase Inhibitors; Mammary Arteries; Propionates; Pyrazoles; Quinolines; Receptors, Thromboxane; Substance P; Thromboxane B2; Thromboxane-A Synthase; Vasoconstriction | 2000 |
Blockade of eosinophil migration and airway hyperresponsiveness by cPLA2-inhibition.
Topics: Animals; Antigens; Azepines; Benzoquinones; Bronchoconstriction; Butyrophenones; Eicosapentaenoic Acid; Enzyme Inhibitors; Eosinophils; Guinea Pigs; Indomethacin; Male; Methacholine Chloride; Phospholipases A; Phospholipases A2; Piperidines; Respiratory Hypersensitivity; Triazoles | 2001 |
5-Lipoxygenase and human pulmonary artery endothelial cell proliferation.
Topics: Apoptosis; Arachidonate 5-Lipoxygenase; Benzoquinones; Cell Division; Cells, Cultured; Comet Assay; Cyclooxygenase Inhibitors; Endothelium, Vascular; Growth Substances; Humans; Indoles; Indomethacin; Lipoxygenase Inhibitors; Masoprocol; Oligonucleotides, Antisense; Pulmonary Artery; S Phase; Thymidine; Transfection; Tritium | 2002 |
Bothrops lanceolatus (Fer de lance) venom stimulates leukocyte migration into the peritoneal cavity of mice.
Topics: Animals; Azepines; Benzoquinones; Bothrops; Cell Migration Inhibition; Crotalid Venoms; Dexamethasone; Dose-Response Relationship, Drug; Indomethacin; Injections, Intraperitoneal; Macrophages; Male; Mice; Mice, Inbred BALB C; Neutrophils; Phospholipases A; Triazoles | 2003 |
Pharmacological modulation of TNF production in macrophages.
Topics: Animals; Benzoquinones; Cell Line; Cyclooxygenase Inhibitors; Ibuprofen; Indomethacin; Lipopolysaccharides; Lipoxygenase Inhibitors; Macrophage Activation; Macrophages; Mice; Pentoxifylline; Tumor Necrosis Factor-alpha | 2004 |
Neuroprotective effects of arachidonic acid against oxidative stress on rat hippocampal slices.
Topics: Animals; Arachidonic Acid; Benzhydryl Compounds; Benzoquinones; Brain Ischemia; Catalase; Cycloheximide; Epoxy Compounds; Glutathione Peroxidase; Hippocampus; Indoles; Indomethacin; Linoleic Acid; Lipoxygenase Inhibitors; Male; Neuroprotective Agents; Oxidative Stress; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2006 |
Mechanisms involved in the rat peritoneal leukocyte migration induced by a Kunitz-type inhibitor isolated from Dimorphandra mollis seeds.
Topics: Analysis of Variance; Animals; Benzoquinones; Celecoxib; Cell Movement; Dexamethasone; Fabaceae; Indomethacin; Inflammation; Leukocytes; Male; NG-Nitroarginine Methyl Ester; Peptides; Peritoneal Lavage; Piperidines; Plant Proteins; Pyrazoles; Quinuclidines; Rats; Rats, Wistar; Seeds; Sulfonamides | 2009 |
Ccl2 and Ccl3 mediate neutrophil recruitment via induction of protein synthesis and generation of lipid mediators.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Benzoquinones; Cells, Cultured; Chemokine CCL2; Chemokine CCL3; Chemotaxis, Leukocyte; Dactinomycin; Disease Models, Animal; Indoles; Indomethacin; Leukotriene B4; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred BALB C; Neutrophil Infiltration; Protein Biosynthesis; Random Allocation; Sensitivity and Specificity | 2009 |
Intracellular mechanisms involved in docosahexaenoic acid-induced increases in tight junction permeability in Caco-2 cell monolayers.
Topics: Benzoquinones; Caco-2 Cells; Calcium; Cyclooxygenase Inhibitors; Docosahexaenoic Acids; Humans; Indomethacin; Lipoxygenase Inhibitors; Permeability; Protein Kinase C; Tight Junctions; Type C Phospholipases | 2010 |
Role of nitric oxide-synthase and cyclooxygenase/lipooxygenase systems in development of experimental ulcerative colitis.
Topics: Acetic Acid; Animals; Antioxidants; Arachidonate 5-Lipoxygenase; Arginine; Benzoquinones; Celecoxib; Colitis, Ulcerative; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Female; Guanidines; Indomethacin; Intestine, Large; Leukotriene B4; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Pyrazoles; Rats; Sulfonamides | 2011 |