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a-factor (streptomyces) and streptomycin

a-factor (streptomyces) has been researched along with streptomycin in 28 studies

Compound Research Comparison

Studies
(a-factor (streptomyces))
Trials
(a-factor (streptomyces))
Recent Studies (post-2010)
(a-factor (streptomyces))
Studies
(streptomycin)
Trials
(streptomycin)
Recent Studies (post-2010) (streptomycin)
960722,2273621,157

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19906 (21.43)18.7374
1990's13 (46.43)18.2507
2000's8 (28.57)29.6817
2010's1 (3.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Khokhlov, AS; Kornitskaya, EY; Tovarova, II; Zaslavskaya, PL; Zhukov, VG1
Beppu, T; Hong, SK; Horinouchi, S; Ueda, K; Vujaklija, D1
Beppu, T; Horinouchi, S; Kuzuyama, T; Miyake, K1
Ochi, K1
Anisova, LN; Efremenkova, OV; Khokhlov, AS1
Beppu, T; Hara, O2
Beppu, T; Horinouchi, S; Kumada, Y1
Ando, N; Beppu, T; Horinouchi, S; Nihira, T; Onaka, H; Yamada, Y1
Beppu, T1
Beppu, T; Horinouchi, S2
Beppu, T; Horinouchi, S; Vujaklija, D1
Horinouchi, S; Onaka, H; Sugiyama, M1
Ando, N; Horinouchi, S; Ueda, K1
Ando, N; Beppu, T; Horinouchi, S; Matsumori, N; Sakuda, S1
Horinouchi, S; Kang, DK; Li, XM; Ochi, K1
Horinouchi, S; Ohnishi, Y1
Horinouchi, S; Kameyama, S; Ohnishi, Y; Onaka, H1
Beppu, T; Endo, K; Hosono, K; Kamo, K; Ueda, K1
Horinouchi, S; Kang, DK; Ohnishi, Y1
Horinouchi, S1
Horinouchi, S; Kato, JY; Mashiko, M; Miyahisa, I; Ohnishi, Y1
Horinouchi, S; Ohnishi, Y; Tomono, A; Tsai, Y; Yamazaki, H1
Baumberg, S; Hong, B; McDowall, KJ; Phornphisutthimas, S; Tilley, E1
Hara, H; Hattori, M; Horinouchi, S; Ikeda, H; Ikenoya, M; Ishikawa, J; Ohnishi, Y; Suzuki, H; Yamashita, A1
Hara, H; Horinouchi, S; Ohnishi, Y1
Higo, A; Horinouchi, S; Ohnishi, Y1

Reviews

6 review(s) available for a-factor (streptomyces) and streptomycin

ArticleYear
Signal transduction and secondary metabolism: prospects for controlling productivity.
    Trends in biotechnology, 1995, Volume: 13, Issue:7

    Topics: 4-Butyrolactone; DNA-Binding Proteins; Genes, Bacterial; Models, Genetic; Protein Serine-Threonine Kinases; Signal Transduction; Spores; Streptomyces; Streptomycin

1995
A-factor as a microbial hormone that controls cellular differentiation and secondary metabolism in Streptomyces griseus.
    Molecular microbiology, 1994, Volume: 12, Issue:6

    Topics: 4-Butyrolactone; Growth Substances; Models, Biological; Streptomyces griseus; Streptomycin

1994
Autoregulators.
    Biotechnology (Reading, Mass.), 1995, Volume: 28

    Topics: 4-Butyrolactone; Gene Expression Regulation, Bacterial; Genes, Bacterial; Growth Substances; Species Specificity; Streptomyces; Streptomycin; Structure-Activity Relationship

1995
[Regulation of secondary metabolism and morphological differentiation by a microbial hormone in streptomyces].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1999, Volume: 44, Issue:11

    Topics: 4-Butyrolactone; Amino Acid Sequence; Bacterial Proteins; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Developmental; Genes, Bacterial; Molecular Sequence Data; Repressor Proteins; Signal Transduction; Streptomyces griseus; Streptomycin; Transcription Factors

1999
The A-factor regulatory cascade and cAMP in the regulation of physiological and morphological development in Streptomyces griseus.
    Journal of industrial microbiology & biotechnology, 2001, Volume: 27, Issue:3

    Topics: 4-Butyrolactone; Bacterial Proteins; Cyclic AMP; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Repressor Proteins; Streptomyces griseus; Streptomycin

2001
A microbial hormone, A-factor, as a master switch for morphological differentiation and secondary metabolism in Streptomyces griseus.
    Frontiers in bioscience : a journal and virtual library, 2002, Oct-01, Volume: 7

    Topics: 4-Butyrolactone; Bacterial Proteins; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Growth Substances; Models, Biological; Repressor Proteins; Signal Transduction; Streptomyces griseus; Streptomycin

2002

Other Studies

22 other study(ies) available for a-factor (streptomyces) and streptomycin

ArticleYear
Influence of A-factor on the ultrastructure of the A-factor deficient mutant of Streptomyces griseus.
    Microbios, 1979, Volume: 25, Issue:101-102

    Topics: 4-Butyrolactone; Anti-Bacterial Agents; Growth Substances; Microscopy, Electron; Mutation; Streptomyces griseus; Streptomycin

1979
Identification of an A-factor-dependent promoter in the streptomycin biosynthetic gene cluster of Streptomyces griseus.
    Molecular & general genetics : MGG, 1991, Volume: 229, Issue:1

    Topics: 4-Butyrolactone; Base Sequence; Gene Expression Regulation, Fungal; Genes, Regulator; Growth Substances; Kinetics; Malate Dehydrogenase; Molecular Sequence Data; Multigene Family; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Plasmids; Promoter Regions, Genetic; Recombinant Fusion Proteins; Single-Strand Specific DNA and RNA Endonucleases; Streptomyces griseus; Streptomycin

1991
The A-factor-binding protein of Streptomyces griseus negatively controls streptomycin production and sporulation.
    Journal of bacteriology, 1990, Volume: 172, Issue:6

    Topics: 4-Butyrolactone; Carrier Proteins; Drug Resistance, Microbial; Growth Substances; Mutation; Phenotype; Pigments, Biological; Repressor Proteins; Spores, Bacterial; Streptomyces griseus; Streptomycin; Transcription Factors

1990
Metabolic initiation of differentiation and secondary metabolism by Streptomyces griseus: significance of the stringent response (ppGpp) and GTP content in relation to A factor.
    Journal of bacteriology, 1987, Volume: 169, Issue:8

    Topics: 4-Butyrolactone; Adenosine; Genes, Bacterial; Growth Substances; Guanine Nucleotides; Guanosine Tetraphosphate; Guanosine Triphosphate; Mutation; Spores, Bacterial; Streptomyces griseus; Streptomycin

1987
[Hybridization of A-factor deficient mutants of Streptomyces griseus by means of fusion of protoplasts].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1988, Volume: 33, Issue:10

    Topics: 4-Butyrolactone; Growth Substances; Hybridization, Genetic; Mutation; Protoplasts; Streptomyces griseus; Streptomycin

1988
Induction of streptomycin-inactivating enzyme by A-factor in Streptomyces griseus.
    The Journal of antibiotics, 1982, Volume: 35, Issue:9

    Topics: 4-Butyrolactone; Drug Resistance, Microbial; Enzyme Induction; Growth Substances; NADP; Phosphorylation; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Streptomyces; Streptomyces griseus; Streptomycin; Time Factors

1982
Unstable genetic determinant of A-factor biosynthesis in streptomycin-producing organisms: cloning and characterization.
    Journal of bacteriology, 1984, Volume: 158, Issue:2

    Topics: 4-Butyrolactone; Cloning, Molecular; DNA, Bacterial; Genes; Genes, Bacterial; Genes, Regulator; Genetic Complementation Test; Growth Substances; Mutation; Nucleic Acid Hybridization; Phenotype; Plasmids; Streptomyces; Streptomyces griseus; Streptomycin

1984
Mutants blocked in streptomycin production in Streptomyces griseus - the role of A-factor.
    The Journal of antibiotics, 1982, Volume: 35, Issue:3

    Topics: 4-Butyrolactone; Chromatography, High Pressure Liquid; Culture Media; Growth Substances; Hot Temperature; Mutation; Streptomyces griseus; Streptomycin; Time Factors

1982
Cloning and characterization of the A-factor receptor gene from Streptomyces griseus.
    Journal of bacteriology, 1995, Volume: 177, Issue:21

    Topics: 4-Butyrolactone; Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; Cloning, Molecular; DNA-Binding Proteins; Drug Resistance, Microbial; Escherichia coli; Gene Expression Regulation, Bacterial; Genes, Bacterial; Helix-Turn-Helix Motifs; Molecular Sequence Data; Morphogenesis; Polymerase Chain Reaction; Recombinant Proteins; Repressor Proteins; Restriction Mapping; Sequence Analysis; Sequence Homology, Amino Acid; Streptomyces griseus; Streptomycin

1995
Detection of an A-factor-responsive protein that binds to the upstream activation sequence of strR, a regulatory gene for streptomycin biosynthesis in Streptomyces griseus.
    Journal of bacteriology, 1993, Volume: 175, Issue:9

    Topics: 4-Butyrolactone; Adenosine Triphosphate; Bacterial Proteins; Base Sequence; DNA-Binding Proteins; DNA, Bacterial; Gene Expression Regulation, Bacterial; Genes, Regulator; Models, Genetic; Molecular Sequence Data; Regulatory Sequences, Nucleic Acid; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid; Streptomyces griseus; Streptomycin; Transcription, Genetic

1993
A mutation at proline-115 in the A-factor receptor protein of Streptomyces griseus abolishes DNA-binding ability but not ligand-binding ability.
    Journal of bacteriology, 1997, Volume: 179, Issue:8

    Topics: 4-Butyrolactone; Animals; Bacterial Proteins; Cattle; DNA Mutational Analysis; DNA-Binding Proteins; Growth Substances; Ligands; Molecular Weight; Mutation; Proline; Repressor Proteins; Spores, Bacterial; Streptomyces; Streptomycin

1997
A Streptomyces griseus gene (sgaA) suppresses the growth disturbance caused by high osmolality and a high concentration of A-factor during early growth.
    Microbiology (Reading, England), 1997, Volume: 143 ( Pt 8)

    Topics: 4-Butyrolactone; Amino Acid Sequence; Bacterial Proteins; Cell Division; DNA-Binding Proteins; Dose-Response Relationship, Drug; Gene Dosage; Gene Expression Regulation, Bacterial; Genes, Bacterial; Genes, Suppressor; Growth Substances; Molecular Sequence Data; Morphogenesis; Osmotic Pressure; Plasmids; Repressor Proteins; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Streptomyces griseus; Streptomycin

1997
Involvement of afsA in A-factor biosynthesis as a key enzyme.
    The Journal of antibiotics, 1997, Volume: 50, Issue:10

    Topics: 4-Butyrolactone; Bacterial Proteins; Cerulenin; Chromatography, High Pressure Liquid; Escherichia coli; Fatty Acids; Growth Substances; Models, Biological; Mutation; Recombinant Proteins; Streptomyces griseus; Streptomycin

1997
Possible involvement of cAMP in aerial mycelium formation and secondary metabolism in Streptomyces griseus.
    Microbiology (Reading, England), 1999, Volume: 145 ( Pt 5)

    Topics: 4-Butyrolactone; Adenylyl Cyclases; Bacterial Proteins; Blotting, Western; Cyclic AMP; DNA-Binding Proteins; Gene Deletion; Guanosine Tetraphosphate; Molecular Sequence Data; Phosphotyrosine; Repressor Proteins; Streptomyces griseus; Streptomycin

1999
The A-factor regulatory cascade leading to streptomycin biosynthesis in Streptomyces griseus : identification of a target gene of the A-factor receptor.
    Molecular microbiology, 1999, Volume: 34, Issue:1

    Topics: 4-Butyrolactone; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Binding Sites; Cloning, Molecular; Conserved Sequence; DNA-Binding Proteins; Molecular Sequence Data; Polymerase Chain Reaction; Promoter Regions, Genetic; Repressor Proteins; Signal Transduction; Streptomyces griseus; Streptomycin; Trans-Activators; Transcription Factors; Transcription, Genetic

1999
Characterization of mutants defective in melanogenesis and a gene for tyrosinase of Streptomyces griseus.
    The Journal of antibiotics, 2001, Volume: 54, Issue:10

    Topics: 4-Butyrolactone; Amino Acid Sequence; Anti-Bacterial Agents; Cell Differentiation; Cloning, Molecular; DNA, Fungal; Melanins; Molecular Sequence Data; Monophenol Monooxygenase; Mutagenesis; Mutagens; Mutation; Nitrosoguanidines; Open Reading Frames; Phenotype; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; Streptomyces griseus; Streptomycin

2001
A single target is sufficient to account for the biological effects of the A-factor receptor protein of Streptomyces griseus.
    Journal of bacteriology, 2004, Volume: 186, Issue:7

    Topics: 4-Butyrolactone; Bacterial Proteins; Culture Media; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Mutation; Promoter Regions, Genetic; Repressor Proteins; Streptomyces griseus; Streptomycin; Trans-Activators; Transcription, Genetic

2004
Transcriptional control by A-factor of strR, the pathway-specific transcriptional activator for streptomycin biosynthesis in Streptomyces griseus.
    Journal of bacteriology, 2005, Volume: 187, Issue:16

    Topics: 4-Butyrolactone; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Binding Sites; Deoxyribonuclease I; DNA Footprinting; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Molecular Sequence Data; Multigene Family; Mutation; Promoter Regions, Genetic; Streptomyces griseus; Streptomycin; Trans-Activators; Transcription Factors; Transcription, Genetic

2005
Streptomycin production by Streptomyces griseus can be modulated by a mechanism not associated with change in the adpA component of the A-factor cascade.
    Biotechnology letters, 2007, Volume: 29, Issue:1

    Topics: 4-Butyrolactone; Bacterial Proteins; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Genetic Enhancement; Streptomyces griseus; Streptomycin; Trans-Activators

2007
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.
    Journal of bacteriology, 2008, Volume: 190, Issue:11

    Topics: 4-Butyrolactone; Base Sequence; Gene Expression Regulation, Bacterial; Genome, Bacterial; Molecular Sequence Data; Multigene Family; Oligonucleotide Array Sequence Analysis; Streptomyces; Streptomyces coelicolor; Streptomyces griseus; Streptomycin; Telomere

2008
DNA microarray analysis of global gene regulation by A-factor in Streptomyces griseus.
    Microbiology (Reading, England), 2009, Volume: 155, Issue:Pt 7

    Topics: 4-Butyrolactone; Bacterial Proteins; Cluster Analysis; DNA, Bacterial; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Genes, Bacterial; Oligonucleotide Array Sequence Analysis; RNA, Bacterial; Streptomyces griseus; Streptomycin; Time Factors; Trans-Activators; Transcription, Genetic

2009
Strict regulation of morphological differentiation and secondary metabolism by a positive feedback loop between two global regulators AdpA and BldA in Streptomyces griseus.
    Molecular microbiology, 2011, Volume: 81, Issue:6

    Topics: 4-Butyrolactone; Base Sequence; DNA-Binding Proteins; Feedback, Physiological; Gene Deletion; Gene Expression; Gene Expression Regulation, Bacterial; Models, Biological; Molecular Sequence Data; RNA, Transfer; Sequence Homology, Nucleic Acid; Streptomyces griseus; Streptomycin; Trans-Activators

2011