Page last updated: 2024-09-03

a-factor (streptomyces) and 4-butyrolactone

a-factor (streptomyces) has been researched along with 4-butyrolactone in 81 studies

Compound Research Comparison

Studies (a-factor (streptomyces))	Trials (a-factor (streptomyces))	Recent Studies (post-2010) (a-factor (streptomyces))	Studies (4-butyrolactone)	Trials (4-butyrolactone)	Recent Studies (post-2010) (4-butyrolactone)
96	0	7	4,456	78	1,823

Research

Studies (81)

Timeframe	Studies, this research(%)	All Research%
pre-1990	18 (22.22)	18.7374
1990's	33 (40.74)	18.2507
2000's	25 (30.86)	29.6817
2010's	4 (4.94)	24.3611
2020's	1 (1.23)	2.80

Authors

Authors	Studies
Khokhlov, AS; Kornitskaya, EY; Tovarova, II; Zaslavskaya, PL; Zhukov, VG	1
Beppu, T; Hopwood, DA; Horinouchi, S; Ishizuka, H; Kieser, HM	1
Kaiser, D; Kuspa, A; Plamann, L	1
Beppu, T; Horinouchi, S	5
Beppu, T; Hong, SK; Horinouchi, S; Ueda, K; Vujaklija, D	1
Beppu, T; Horinouchi, S; Kuzuyama, T; Miyake, K	1
Beppu, T; Horinouchi, S; Suzuki, H	1
Beppu, T; Horinouchi, S; Nishiyama, M; Suzuki, H	1
Beppu, T; Chiba, N; Horinouchi, S; Miyake, K; Mori, K; Morikawa, N; Nogawa, N; Yoshida, M	1
Ochi, K	1
Anisova, LN; Efremenkova, OV; Khokhlov, AS	1
Duncan, JS; Hutchinson, CR; Kinashi, H; Otten, SL	1
Anisova, LN; Dmitrieva, SV; Efremenkova, OV; Gorin, SE; Kamzolkina, OV	1
Anisova, LN; Bartoshevich, IuE; Efremenkova, OV	1
Eritt, I; Gräfe, U; Riesenberg, D	1
Anisova, LN; Bartoshevich, IuE; Krakhmaleva, IN; Sazykin, IuO; Telesnina, GN	1
Beppu, T; Horinouchi, S; Kumada, Y; Nishiyama, M; Suzuki, H	1
Beppu, T; Hara, O	2
Beppu, T; Hara, O; Horinouchi, S	1
Beppu, T; Hara, O; Horinouchi, S; Uozumi, T	1
Eritt, I; Gräfe, U; Krebs, D; Reinhardt, G; Steudel, A	1
Beppu, T; Horinouchi, S; Kumada, Y	1
Ando, N; Beppu, T; Horinouchi, S; Nihira, T; Onaka, H; Yamada, Y	1
Beppu, T; Horinouchi, S; Kimura, M; Kudo, N	1
Horinouchi, S	2
Beppu, T	1
Distler, J; Kasberg, T; Kuberski, S	1
Beppu, T; Horinouchi, S; Miyake, K; Ueda, K	1
Beppu, T; Horinouchi, S; Vujaklija, D	1
Beppu, T; Horinouchi, S; Ueda, K; Umeyama, T	1
Klavehn, P; Schmitt, MJ; Schönig, I; Tipper, DJ; Wang, J	1
Aigle, BD; Horinouchi, S; Tanabe, Y; Umeyama, T	1
Khouri, O; Roise, D; Sherrill, C	1
Beppu, T; Goshi, K; Horinouchi, S; Kameoka, D; Kinashi, H; Lezhava, A; Nimi, O; Shinkawa, H; Sugino, H	1
Horinouchi, S; Onaka, H; Sugiyama, M	1
Bíró, S; Szabó, G; Szeszák, F; Vitális, S	1
Ando, N; Horinouchi, S; Ueda, K	1
Ando, N; Beppu, T; Horinouchi, S; Matsumori, N; Sakuda, S	1
Harris, BZ; Kaiser, D; Singer, M	1
Horinouchi, S; Nakagawa, T; Onaka, H	1
Beppu, T; Horinouchi, S; Hsheh, CW; Shinkawa, H; Tosaki, T; Ueda, K	1
Horinouchi, S; Nakagawa, T; Onaka, H; Sugiyama, M	1
Hoch, JA	1
Horinouchi, S; Kang, DK; Li, XM; Ochi, K	1
Horinouchi, S; Ohnishi, Y	1
Horinouchi, S; Kameyama, S; Ohnishi, Y; Onaka, H	1
Michaelis, S; Schmidt, WK; Tam, A	1
Horinouchi, S; Ohnishi, Y; Yamazaki, H	2
Horinouchi, S; Kameyama, S; Nishiyama, Y; Ohnishi, Y; Sato, R	1
Beppu, T; Endo, K; Hosono, K; Kamo, K; Ueda, K	1
Horinouchi, S; Kang, DK; Ohnishi, Y	1
Gill, RE; Tse, H	1
Beppu, T; Endo, K; Hosono, K; Ueda, K	1
Horinouchi, S; Kato, JY; Ohnishi, Y; Suzuki, A; Yamazaki, H	1
Horinouchi, S; Ohnishi, Y; Seo, JW	1
Yan, Z	1
Abe, H; Hashimoto, M; Kawaide, H; Kondo, T; Kozone, I; Natsume, M	1
Dudnik, IuV; Efremenkova, OV; Gruzina, VD; Reznikova, MI; Zenkova, VA	1
Horinouchi, S; Ohnishi, Y; Takano, Y; Yamazaki, H	1
Horinouchi, S; Kato, JY; Mashiko, M; Miyahisa, I; Ohnishi, Y	1
Chi, WJ; Hong, SK; Horinouchi, S; Kato, JY; Ohnishi, Y	1
Horinouchi, S; Kato, JY; Ohnishi, Y; Tomono, A; Yamazaki, H	1
Horinouchi, S; Ohnishi, Y; Tomono, A; Tsai, Y; Yamazaki, H	1
Horinouchi, S; Ohnishi, Y; Tomono, A; Tsai, Y	1
Baumberg, S; Hong, B; McDowall, KJ; Phornphisutthimas, S; Tilley, E	1
Higashi, T; Horinouchi, S; Iwasaki, Y; Ohnishi, Y	1
Bialek, S; Birkó, Z; Biró, S; Buzás, K; Kele, Z; Medzihradszky, KF; Penyige, A; Rigali, S; Szájli, E; Traag, BA; van Wezel, GP; Vijgenboom, E	1
Hara, H; Hattori, M; Horinouchi, S; Ikeda, H; Ikenoya, M; Ishikawa, J; Ohnishi, Y; Suzuki, H; Yamashita, A	1
Hara, H; Horinouchi, S; Ohnishi, Y	1
Chi, WJ; Hong, SK; Jin, XM; Jung, SC; Oh, EA	1
Higo, A; Horinouchi, S; Ohnishi, Y	1
Grunenberg, J; Kern, S; Kudo, Y; Moore, BS; Schlawis, C; Schulz, S	1
Birkó, Z; Biró, S; Kele, Z; Lukács, D; Márton, É; Szilágyi, M	1
Lu, Y; Wu, Y; Xiong, Z; Zhang, S; Zhang, X	1

Reviews

15 review(s) available for a-factor (streptomyces) and 4-butyrolactone

Article	Year
Regulation of secondary metabolism and cell differentiation in Streptomyces: A-factor as a microbial hormone and the AfsR protein as a component of a two-component regulatory system. Gene, 1992, Jun-15, Volume: 115, Issue:1-2 Topics: 4-Butyrolactone; Bacterial Proteins; DNA-Binding Proteins; Growth Substances; Homeostasis; Repressor Proteins; Streptomyces; Transcription Factors	1992
Molecular mechanisms of the A-factor-dependent control of secondary metabolism in Streptomyces. Planta medica, 1991, Volume: 57, Issue:7 Topics: 4-Butyrolactone; Gene Expression Regulation, Fungal; Genes, Fungal; Genes, Regulator; Growth Substances; Protein Binding; Repressor Proteins; Streptomyces	1991
Autoregulatory factors of secondary metabolism and morphogenesis in actinomycetes. Critical reviews in biotechnology, 1990, Volume: 10, Issue:3 Topics: 4-Butyrolactone; Growth Substances; Homeostasis; Morphogenesis; Streptomyces	1990
[Regulators of actinomycete differentiation]. Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology, 1985, Volume: 30, Issue:9 Topics: 4-Butyrolactone; Actinomycetales; Adenosine Diphosphate; Adenosine Triphosphate; Anti-Bacterial Agents; Chemical Phenomena; Chemistry; DNA, Bacterial; Drug Resistance, Microbial; Genes, Bacterial; Growth Substances; Morphogenesis; Mutation; Pentose Phosphate Pathway; Plasmids; Transformation, Bacterial	1985
[Signal transduction involved in antibiotic production and morphogenesis in Streptomyces]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1995, Volume: 40, Issue:8 Topics: 4-Butyrolactone; Amino Acid Sequence; Anti-Bacterial Agents; Molecular Sequence Data; Protein Serine-Threonine Kinases; Signal Transduction; Streptomyces	1995
Signal transduction and secondary metabolism: prospects for controlling productivity. Trends in biotechnology, 1995, Volume: 13, Issue:7 Topics: 4-Butyrolactone; DNA-Binding Proteins; Genes, Bacterial; Models, Genetic; Protein Serine-Threonine Kinases; Signal Transduction; Spores; Streptomyces; Streptomycin	1995
A-factor as a microbial hormone that controls cellular differentiation and secondary metabolism in Streptomyces griseus. Molecular microbiology, 1994, Volume: 12, Issue:6 Topics: 4-Butyrolactone; Growth Substances; Models, Biological; Streptomyces griseus; Streptomycin	1994
Autoregulators. Biotechnology (Reading, Mass.), 1995, Volume: 28 Topics: 4-Butyrolactone; Gene Expression Regulation, Bacterial; Genes, Bacterial; Growth Substances; Species Specificity; Streptomyces; Streptomycin; Structure-Activity Relationship	1995
Initiation of bacterial development. Current opinion in microbiology, 1998, Volume: 1, Issue:2 Topics: 4-Butyrolactone; Bacteria; Bacterial Physiological Phenomena; Cell Cycle; Gene Expression Regulation, Bacterial; GTP Phosphohydrolases; Phosphoprotein Phosphatases; Protein Kinase Inhibitors; Protein Kinases; Spores, Bacterial	1998
[Regulation of secondary metabolism and morphological differentiation by a microbial hormone in streptomyces]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1999, Volume: 44, Issue:11 Topics: 4-Butyrolactone; Amino Acid Sequence; Bacterial Proteins; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Developmental; Genes, Bacterial; Molecular Sequence Data; Repressor Proteins; Signal Transduction; Streptomyces griseus; Streptomycin; Transcription Factors	1999
The A-factor regulatory cascade and cAMP in the regulation of physiological and morphological development in Streptomyces griseus. Journal of industrial microbiology & biotechnology, 2001, Volume: 27, Issue:3 Topics: 4-Butyrolactone; Bacterial Proteins; Cyclic AMP; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Repressor Proteins; Streptomyces griseus; Streptomycin	2001
A microbial hormone, A-factor, as a master switch for morphological differentiation and secondary metabolism in Streptomyces griseus. Frontiers in bioscience : a journal and virtual library, 2002, Oct-01, Volume: 7 Topics: 4-Butyrolactone; Bacterial Proteins; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Growth Substances; Models, Biological; Repressor Proteins; Signal Transduction; Streptomyces griseus; Streptomycin	2002
Deprogrammed sporulation in Streptomyces. FEMS microbiology letters, 2002, Oct-29, Volume: 216, Issue:1 Topics: 4-Butyrolactone; Agar; ATP-Binding Cassette Transporters; Culture Media; Gene Expression Regulation, Bacterial; Genes, Bacterial; Glucose; Growth Substances; Mutation; Signal Transduction; Spores, Bacterial; Streptomyces; Streptomyces griseus	2002
[Molecular regulation of a factor in the differentiation and secondary metabolism of prokaryote]. Wei sheng wu xue bao = Acta microbiologica Sinica, 2000, Volume: 40, Issue:1 Topics: 4-Butyrolactone; Bacterial Proteins; DNA-Binding Proteins; Growth Substances; Repressor Proteins; Signal Transduction; Streptomyces	2000
AdpA, a central transcriptional regulator in the A-factor regulatory cascade that leads to morphological development and secondary metabolism in Streptomyces griseus. Bioscience, biotechnology, and biochemistry, 2005, Volume: 69, Issue:3 Topics: 4-Butyrolactone; Bacterial Proteins; Binding Sites; DNA-Binding Proteins; Regulon; Streptomyces griseus; Trans-Activators; Transcription Factors	2005

Other Studies

66 other study(ies) available for a-factor (streptomyces) and 4-butyrolactone

Article	Year
Influence of A-factor on the ultrastructure of the A-factor deficient mutant of Streptomyces griseus. Microbios, 1979, Volume: 25, Issue:101-102 Topics: 4-Butyrolactone; Anti-Bacterial Agents; Growth Substances; Microscopy, Electron; Mutation; Streptomyces griseus; Streptomycin	1979
A putative two-component regulatory system involved in secondary metabolism in Streptomyces spp. Journal of bacteriology, 1992, Volume: 174, Issue:23 Topics: 4-Butyrolactone; Actinomycetales; Amino Acid Sequence; Anthraquinones; Bacterial Proteins; Base Sequence; Chromosome Mapping; Cloning, Molecular; Gene Expression Regulation, Bacterial; Genes, Bacterial; Genes, Suppressor; Growth Substances; Histidine Kinase; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenotype; Prodigiosin; Protein Kinases; Restriction Mapping; Sequence Alignment; Sequence Homology, Amino Acid; Streptomyces; Transcription, Genetic	1992
A-signalling and the cell density requirement for Myxococcus xanthus development. Journal of bacteriology, 1992, Volume: 174, Issue:22 Topics: 4-Butyrolactone; Amino Acids; Gene Expression; Gene Expression Regulation, Bacterial; Genes, Bacterial; Growth Substances; Hot Temperature; Kinetics; Mutagenesis; Myxococcus xanthus; Phenotype; Proline; Spores, Bacterial	1992
Identification of an A-factor-dependent promoter in the streptomycin biosynthetic gene cluster of Streptomyces griseus. Molecular & general genetics : MGG, 1991, Volume: 229, Issue:1 Topics: 4-Butyrolactone; Base Sequence; Gene Expression Regulation, Fungal; Genes, Regulator; Growth Substances; Kinetics; Malate Dehydrogenase; Molecular Sequence Data; Multigene Family; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Plasmids; Promoter Regions, Genetic; Recombinant Fusion Proteins; Single-Strand Specific DNA and RNA Endonucleases; Streptomyces griseus; Streptomycin	1991
The A-factor-binding protein of Streptomyces griseus negatively controls streptomycin production and sporulation. Journal of bacteriology, 1990, Volume: 172, Issue:6 Topics: 4-Butyrolactone; Carrier Proteins; Drug Resistance, Microbial; Growth Substances; Mutation; Phenotype; Pigments, Biological; Repressor Proteins; Spores, Bacterial; Streptomyces griseus; Streptomycin; Transcription Factors	1990
Nucleotide sequence of afsB, a pleiotropic gene involved in secondary metabolism in Streptomyces coelicolor A3(2) and "Streptomyces lividans". Journal of bacteriology, 1986, Volume: 168, Issue:1 Topics: 4-Butyrolactone; Amino Acid Sequence; Anthraquinones; Bacterial Proteins; Base Sequence; DNA-Binding Proteins; Genes, Bacterial; Growth Substances; Nucleic Acid Hybridization; Plasmids; Prodigiosin; Promoter Regions, Genetic; RNA, Bacterial; RNA, Messenger; Streptomyces; Transcription, Genetic	1986
Nucleotide sequence and transcriptional analysis of the Streptomyces griseus gene (afsA) responsible for A-factor biosynthesis. Journal of bacteriology, 1989, Volume: 171, Issue:2 Topics: 4-Butyrolactone; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Genes; Genes, Bacterial; Growth Substances; Molecular Sequence Data; Mutation; Restriction Mapping; Streptomyces griseus; Transcription, Genetic	1989
Detection and properties of A-factor-binding protein from Streptomyces griseus. Journal of bacteriology, 1989, Volume: 171, Issue:8 Topics: 4-Butyrolactone; Carrier Proteins; Growth Substances; Kinetics; Streptomyces griseus; Tritium	1989
Metabolic initiation of differentiation and secondary metabolism by Streptomyces griseus: significance of the stringent response (ppGpp) and GTP content in relation to A factor. Journal of bacteriology, 1987, Volume: 169, Issue:8 Topics: 4-Butyrolactone; Adenosine; Genes, Bacterial; Growth Substances; Guanine Nucleotides; Guanosine Tetraphosphate; Guanosine Triphosphate; Mutation; Spores, Bacterial; Streptomyces griseus; Streptomycin	1987
[Hybridization of A-factor deficient mutants of Streptomyces griseus by means of fusion of protoplasts]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1988, Volume: 33, Issue:10 Topics: 4-Butyrolactone; Growth Substances; Hybridization, Genetic; Mutation; Protoplasts; Streptomyces griseus; Streptomycin	1988
Frequent loss and restoration of antibiotic production by Streptomyces lasaliensis. The Journal of antibiotics, 1988, Volume: 41, Issue:5 Topics: 4-Butyrolactone; Conjugation, Genetic; Echinomycin; Genes; Genes, Bacterial; Growth Substances; Lasalocid; Mutation; Plasmids; Protoplasts; Quinoxalines; Recombination, Genetic; Streptomyces	1988
[Formation of A-factor-type regulators by representatives of the genus Micromonospora]. Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology, 1987, Volume: 32, Issue:9 Topics: 4-Butyrolactone; Culture Media; Growth Substances; Micromonospora; Sisomicin; Spores, Bacterial; Time Factors	1987
Synergistic effect of cobalt on the induction by A-factor of the formation of aerial mycelium and anthracyclines by a blocked mutant of Streptomyces griseus. Journal of basic microbiology, 1985, Volume: 25, Issue:4 Topics: 4-Butyrolactone; Antibiotics, Antineoplastic; Cobalt; Growth Substances; Mutation; Naphthacenes; Streptomyces griseus	1985
[Valinomycin biosynthesis and the dynamics of the content of macroergic phosphorus compounds in Streptomyces cyaneofuscatus]. Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology, 1986, Volume: 31, Issue:1 Topics: 4-Butyrolactone; Culture Media; Energy Metabolism; Growth Substances; Macromolecular Substances; Mutation; Polyphosphates; Streptomyces; Valinomycin	1986
The cloned Streptomyces bikiniensis A-factor determinant. The Journal of antibiotics, 1985, Volume: 38, Issue:5 Topics: 4-Butyrolactone; Cloning, Molecular; DNA, Bacterial; Growth Substances; Operon; Plasmids; Streptomyces	1985
Induction of streptomycin-inactivating enzyme by A-factor in Streptomyces griseus. The Journal of antibiotics, 1982, Volume: 35, Issue:9 Topics: 4-Butyrolactone; Drug Resistance, Microbial; Enzyme Induction; Growth Substances; NADP; Phosphorylation; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Streptomyces; Streptomyces griseus; Streptomycin; Time Factors	1982
Cloning of a pleiotropic gene that positively controls biosynthesis of A-factor, actinorhodin, and prodigiosin in Streptomyces coelicolor A3(2) and Streptomyces lividans. Journal of bacteriology, 1983, Volume: 155, Issue:3 Topics: 4-Butyrolactone; Anthraquinones; Cloning, Molecular; DNA Restriction Enzymes; Genes, Bacterial; Genes, Regulator; Growth Substances; Mutation; Pigments, Biological; Plasmids; Prodigiosin; Streptomyces	1983
Genetic analysis of A-factor synthesis in Streptomyces coelicolor A3(2) and Streptomyces griseus. Journal of general microbiology, 1983, Volume: 129, Issue:9 Topics: 4-Butyrolactone; Chromosome Mapping; Chromosomes, Bacterial; Conjugation, Genetic; Genetic Linkage; Growth Substances; Mutation; Protoplasts; Streptomyces; Streptomyces griseus	1983
Effect of the autoregulator from Streptomyces griseus JA 5142 on surface cultures of blocked mutant ZIMET 43682. Zeitschrift fur allgemeine Mikrobiologie, 1983, Volume: 23, Issue:6 Topics: 4-Butyrolactone; Daunorubicin; Growth Substances; Mutation; Streptomyces griseus	1983
Unstable genetic determinant of A-factor biosynthesis in streptomycin-producing organisms: cloning and characterization. Journal of bacteriology, 1984, Volume: 158, Issue:2 Topics: 4-Butyrolactone; Cloning, Molecular; DNA, Bacterial; Genes; Genes, Bacterial; Genes, Regulator; Genetic Complementation Test; Growth Substances; Mutation; Nucleic Acid Hybridization; Phenotype; Plasmids; Streptomyces; Streptomyces griseus; Streptomycin	1984
Mutants blocked in streptomycin production in Streptomyces griseus - the role of A-factor. The Journal of antibiotics, 1982, Volume: 35, Issue:3 Topics: 4-Butyrolactone; Chromatography, High Pressure Liquid; Culture Media; Growth Substances; Hot Temperature; Mutation; Streptomyces griseus; Streptomycin; Time Factors	1982
Cloning and characterization of the A-factor receptor gene from Streptomyces griseus. Journal of bacteriology, 1995, Volume: 177, Issue:21 Topics: 4-Butyrolactone; Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; Cloning, Molecular; DNA-Binding Proteins; Drug Resistance, Microbial; Escherichia coli; Gene Expression Regulation, Bacterial; Genes, Bacterial; Helix-Turn-Helix Motifs; Molecular Sequence Data; Morphogenesis; Polymerase Chain Reaction; Recombinant Proteins; Repressor Proteins; Restriction Mapping; Sequence Analysis; Sequence Homology, Amino Acid; Streptomyces griseus; Streptomycin	1995
Cloning and characterization of a gene involved in aerial mycelium formation in Streptomyces griseus. Journal of bacteriology, 1995, Volume: 177, Issue:22 Topics: 4-Butyrolactone; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Cloning, Molecular; Gene Dosage; Genes, Bacterial; Genes, Suppressor; Growth Substances; Molecular Sequence Data; Morphogenesis; Multigene Family; Mutagenesis; Open Reading Frames; Restriction Mapping; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Spores, Bacterial; Streptomyces griseus	1995
The nusG gene of Streptomyces griseus: cloning of the gene and analysis of the A-factor binding properties of the gene product. FEMS microbiology letters, 1994, Jun-01, Volume: 119, Issue:1-2 Topics: 4-Butyrolactone; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Cloning, Molecular; Escherichia coli Proteins; Genes, Bacterial; Molecular Sequence Data; Peptide Elongation Factors; Streptomyces griseus; Transcription Factors	1994
A gene cluster involved in aerial mycelium formation in Streptomyces griseus encodes proteins similar to the response regulators of two-component regulatory systems and membrane translocators. Journal of bacteriology, 1993, Volume: 175, Issue:7 Topics: 4-Butyrolactone; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Cloning, Molecular; DNA-Binding Proteins; Escherichia coli Proteins; Genes, Bacterial; Genes, Regulator; Genetic Complementation Test; Growth Substances; Molecular Sequence Data; Morphogenesis; Multigene Family; Mutagenesis, Site-Directed; Open Reading Frames; Restriction Mapping; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Signal Transduction; Spores, Bacterial; Streptomyces griseus	1993
Detection of an A-factor-responsive protein that binds to the upstream activation sequence of strR, a regulatory gene for streptomycin biosynthesis in Streptomyces griseus. Journal of bacteriology, 1993, Volume: 175, Issue:9 Topics: 4-Butyrolactone; Adenosine Triphosphate; Bacterial Proteins; Base Sequence; DNA-Binding Proteins; DNA, Bacterial; Gene Expression Regulation, Bacterial; Genes, Regulator; Models, Genetic; Molecular Sequence Data; Regulatory Sequences, Nucleic Acid; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid; Streptomyces griseus; Streptomycin; Transcription, Genetic	1993
The aerial mycelium-defective phenotype of Streptomyces griseus resulting from A-factor deficiency is suppressed by a Ser/Thr kinase of S. coelicolor A3(2). Gene, 1996, Feb-22, Volume: 169, Issue:1 Topics: 4-Butyrolactone; Carbazoles; Cell Differentiation; Enzyme Inhibitors; Genes, Suppressor; Indole Alkaloids; Protein Kinase C; Protein Serine-Threonine Kinases; Restriction Mapping; Spores, Bacterial; Streptomyces; Streptomyces griseus	1996
Cell cycle studies on the mode of action of yeast K28 killer toxin. Microbiology (Reading, England), 1996, Volume: 142 ( Pt 9) Topics: 4-Butyrolactone; Cell Cycle; Cell Death; DNA; Flow Cytometry; Fluorescent Antibody Technique, Direct; Killer Factors, Yeast; Microtubules; Mycotoxins; S Phase; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins	1996
Expression of the Streptomyces coelicolor A3(2) ptpA gene encoding a phosphotyrosine protein phosphatase leads to overproduction of secondary metabolites in S. lividans. FEMS microbiology letters, 1996, Nov-01, Volume: 144, Issue:2-3 Topics: 4-Butyrolactone; Anthraquinones; Bacterial Proteins; Cloning, Molecular; DNA, Bacterial; Enzyme Induction; Gene Expression Regulation, Bacterial; Gene Library; Gene Targeting; Genes, Bacterial; Phenotype; Pigments, Biological; Prodigiosin; Protein Tyrosine Phosphatases; Species Specificity; Streptomyces	1996
Partitioning of a-factor analogues into membranes: analysis of binding and importance for biological activity. Biochemistry, 1996, Nov-19, Volume: 35, Issue:46 Topics: 4-Butyrolactone; Binding Sites; Growth Substances; Kinetics; Structure-Activity Relationship	1996
Chromosomal deletions in Streptomyces griseus that remove the afsA locus. Molecular & general genetics : MGG, 1997, Jan-27, Volume: 253, Issue:4 Topics: 4-Butyrolactone; Chromosomes, Bacterial; Cosmids; Gene Deletion; Genes, Bacterial; Restriction Mapping; Streptomyces griseus	1997
A mutation at proline-115 in the A-factor receptor protein of Streptomyces griseus abolishes DNA-binding ability but not ligand-binding ability. Journal of bacteriology, 1997, Volume: 179, Issue:8 Topics: 4-Butyrolactone; Animals; Bacterial Proteins; Cattle; DNA Mutational Analysis; DNA-Binding Proteins; Growth Substances; Ligands; Molecular Weight; Mutation; Proline; Repressor Proteins; Spores, Bacterial; Streptomyces; Streptomycin	1997
Phenotypic heterogeneity of the progeny of Streptomyces griseus conidia. Acta biologica Hungarica, 1997, Volume: 48, Issue:1 Topics: 4-Butyrolactone; Growth Substances; Hot Temperature; Kinetics; Models, Biological; Mutation; Spores, Bacterial; Streptomyces griseus	1997
A Streptomyces griseus gene (sgaA) suppresses the growth disturbance caused by high osmolality and a high concentration of A-factor during early growth. Microbiology (Reading, England), 1997, Volume: 143 ( Pt 8) Topics: 4-Butyrolactone; Amino Acid Sequence; Bacterial Proteins; Cell Division; DNA-Binding Proteins; Dose-Response Relationship, Drug; Gene Dosage; Gene Expression Regulation, Bacterial; Genes, Bacterial; Genes, Suppressor; Growth Substances; Molecular Sequence Data; Morphogenesis; Osmotic Pressure; Plasmids; Repressor Proteins; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Streptomyces griseus; Streptomycin	1997
Involvement of afsA in A-factor biosynthesis as a key enzyme. The Journal of antibiotics, 1997, Volume: 50, Issue:10 Topics: 4-Butyrolactone; Bacterial Proteins; Cerulenin; Chromatography, High Pressure Liquid; Escherichia coli; Fatty Acids; Growth Substances; Models, Biological; Mutation; Recombinant Proteins; Streptomyces griseus; Streptomycin	1997
The guanosine nucleotide (p)ppGpp initiates development and A-factor production in myxococcus xanthus. Genes & development, 1998, Apr-01, Volume: 12, Issue:7 Topics: 4-Butyrolactone; Amino Acid Sequence; Escherichia coli; Gene Expression; Gene Expression Regulation; Guanosine Tetraphosphate; Ligases; Molecular Sequence Data; Mutation; Myxococcus xanthus; Sequence Alignment; Sequence Homology, Amino Acid	1998
Involvement of two A-factor receptor homologues in Streptomyces coelicolor A3(2) in the regulation of secondary metabolism and morphogenesis. Molecular microbiology, 1998, Volume: 28, Issue:4 Topics: 4-Butyrolactone; Amino Acid Sequence; Anthraquinones; Bacterial Proteins; Base Sequence; Cloning, Molecular; DNA-Binding Proteins; DNA, Bacterial; Genes, Bacterial; Molecular Sequence Data; Prodigiosin; Repressor Proteins; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Streptomyces	1998
Characterization of an A-factor-responsive repressor for amfR essential for onset of aerial mycelium formation in Streptomyces griseus. Journal of bacteriology, 1998, Volume: 180, Issue:19 Topics: 4-Butyrolactone; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Cloning, Molecular; DNA, Bacterial; Gene Expression Regulation, Bacterial; Molecular Sequence Data; Open Reading Frames; Operon; Promoter Regions, Genetic; Protein Binding; Repressor Proteins; RNA, Bacterial; RNA, Messenger; Sequence Analysis, DNA; Streptomyces griseus; Transcription Factors; Transcription, Genetic	1998
Site-directed mutagenesis of the A-factor receptor protein: Val-41 important for DNA-binding and Trp-119 important for ligand-binding. Gene, 1998, Nov-05, Volume: 222, Issue:1 Topics: 4-Butyrolactone; Amino Acid Sequence; Bacterial Proteins; Binding Sites; DNA-Binding Proteins; Growth Substances; Ligands; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Repressor Proteins; Sequence Homology, Amino Acid; Species Specificity; Streptomyces; Streptomyces griseus	1998
Possible involvement of cAMP in aerial mycelium formation and secondary metabolism in Streptomyces griseus. Microbiology (Reading, England), 1999, Volume: 145 ( Pt 5) Topics: 4-Butyrolactone; Adenylyl Cyclases; Bacterial Proteins; Blotting, Western; Cyclic AMP; DNA-Binding Proteins; Gene Deletion; Guanosine Tetraphosphate; Molecular Sequence Data; Phosphotyrosine; Repressor Proteins; Streptomyces griseus; Streptomycin	1999
The A-factor regulatory cascade leading to streptomycin biosynthesis in Streptomyces griseus : identification of a target gene of the A-factor receptor. Molecular microbiology, 1999, Volume: 34, Issue:1 Topics: 4-Butyrolactone; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Binding Sites; Cloning, Molecular; Conserved Sequence; DNA-Binding Proteins; Molecular Sequence Data; Polymerase Chain Reaction; Promoter Regions, Genetic; Repressor Proteins; Signal Transduction; Streptomyces griseus; Streptomycin; Trans-Activators; Transcription Factors; Transcription, Genetic	1999
Reconstitution of the Ste24p-dependent N-terminal proteolytic step in yeast a-factor biogenesis. The Journal of biological chemistry, 2000, Mar-03, Volume: 275, Issue:9 Topics: 4-Butyrolactone; Amino Acid Sequence; Fungal Proteins; Kinetics; Membrane Proteins; Metalloendopeptidases; Molecular Sequence Data; Mutation; Protein Precursors; Protein Processing, Post-Translational; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Substrate Specificity; Zinc	2000
An A-factor-dependent extracytoplasmic function sigma factor (sigma(AdsA)) that is essential for morphological development in Streptomyces griseus. Journal of bacteriology, 2000, Volume: 182, Issue:16 Topics: 4-Butyrolactone; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Binding Sites; Cloning, Molecular; Deoxyribonuclease I; DNA Footprinting; DNA-Binding Proteins; Growth Substances; Molecular Sequence Data; Recombinant Proteins; Restriction Mapping; Sequence Alignment; Sequence Homology, Amino Acid; Sigma Factor; Streptomyces griseus; Trans-Activators	2000
An oligoribonuclease gene in Streptomyces griseus. Journal of bacteriology, 2000, Volume: 182, Issue:16 Topics: 4-Butyrolactone; Amino Acid Sequence; Bacterial Proteins; DNA-Binding Proteins; Exoribonucleases; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Growth Substances; Molecular Sequence Data; Open Reading Frames; Restriction Mapping; Sequence Alignment; Sequence Homology, Amino Acid; Streptomyces griseus; Trans-Activators	2000
Characterization of mutants defective in melanogenesis and a gene for tyrosinase of Streptomyces griseus. The Journal of antibiotics, 2001, Volume: 54, Issue:10 Topics: 4-Butyrolactone; Amino Acid Sequence; Anti-Bacterial Agents; Cell Differentiation; Cloning, Molecular; DNA, Fungal; Melanins; Molecular Sequence Data; Monophenol Monooxygenase; Mutagenesis; Mutagens; Mutation; Nitrosoguanidines; Open Reading Frames; Phenotype; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; Streptomyces griseus; Streptomycin	2001
Bypass of A- and B-signaling requirements for Myxococcus xanthus development by mutations in spdR. Journal of bacteriology, 2002, Volume: 184, Issue:5 Topics: 4-Butyrolactone; Bacterial Proteins; Endopeptidases; Gene Expression Regulation, Bacterial; Mutation; Myxococcus xanthus; Signal Transduction; Transcription Factors	2002
A novel extracytoplasmic phenol oxidase of Streptomyces: its possible involvement in the onset of morphogenesis. Microbiology (Reading, England), 2002, Volume: 148, Issue:Pt 6 Topics: 4-Butyrolactone; Amino Acid Sequence; Bacterial Proteins; Cloning, Molecular; Copper; Kinetics; Molecular Sequence Data; Monophenol Monooxygenase; Morphogenesis; Mutation; Proteins; Streptomyces griseus; Substrate Specificity	2002
Control by A-factor of a metalloendopeptidase gene involved in aerial mycelium formation in Streptomyces griseus. Journal of bacteriology, 2002, Volume: 184, Issue:21 Topics: 4-Butyrolactone; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Binding Sites; Cloning, Molecular; Deoxyribonuclease I; DNA Footprinting; DNA-Binding Proteins; DNA, Bacterial; Genes, Bacterial; Metalloendopeptidases; Molecular Sequence Data; Nucleotides; Phenotype; Sequence Analysis, DNA; Streptomyces griseus; Trans-Activators; Transcription, Genetic; Transcriptional Activation; Zinc Fingers	2002
Transcriptional switch on of ssgA by A-factor, which is essential for spore septum formation in Streptomyces griseus. Journal of bacteriology, 2003, Volume: 185, Issue:4 Topics: 4-Butyrolactone; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Binding Sites; DNA Footprinting; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Genetic Complementation Test; Molecular Sequence Data; Mutation; Spores, Bacterial; Streptomyces griseus; Trans-Activators; Transcription, Genetic; Transcriptional Activation	2003
Relationship between response to and production of the aerial mycelium-inducing substances pamamycin-607 and A-factor. Bioscience, biotechnology, and biochemistry, 2003, Volume: 67, Issue:4 Topics: 4-Butyrolactone; Anti-Bacterial Agents; Calcium; Dose-Response Relationship, Drug; Growth Substances; Homeostasis; Macrolides; Mycelium; Streptomyces	2003
[A-Factor as a selective agent for isolation of the soil Gram-negative bacterium strain--the producent of an antibacterial antibiotic]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2003, Volume: 48, Issue:3 Topics: 4-Butyrolactone; Anti-Bacterial Agents; Colony Count, Microbial; Culture Media; Ecosystem; Gram-Negative Bacteria; Gram-Positive Bacteria; Growth Substances; Soil Microbiology	2003
amfR, an essential gene for aerial mycelium formation, is a member of the AdpA regulon in the A-factor regulatory cascade in Streptomyces griseus. Molecular microbiology, 2003, Volume: 50, Issue:4 Topics: 4-Butyrolactone; Bacterial Proteins; Base Sequence; Binding Sites; DNA Footprinting; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Genes, Bacterial; Genes, Essential; Growth Substances; Molecular Sequence Data; Mutation; Mycelium; Nucleic Acid Conformation; Phenotype; Plasmids; Promoter Regions, Genetic; Protein Binding; Regulon; Signal Transduction; Streptomyces griseus; Trans-Activators; Transcription Factors; Transcription, Genetic	2003
A single target is sufficient to account for the biological effects of the A-factor receptor protein of Streptomyces griseus. Journal of bacteriology, 2004, Volume: 186, Issue:7 Topics: 4-Butyrolactone; Bacterial Proteins; Culture Media; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Mutation; Promoter Regions, Genetic; Repressor Proteins; Streptomyces griseus; Streptomycin; Trans-Activators; Transcription, Genetic	2004
Transcriptional control by A-factor of two trypsin genes in Streptomyces griseus. Journal of bacteriology, 2005, Volume: 187, Issue:1 Topics: 4-Butyrolactone; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Binding Sites; Cloning, Molecular; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Genes, Bacterial; Molecular Sequence Data; Phenotype; Streptomyces griseus; Trans-Activators; Transcription, Genetic; Trypsin	2005
Transcriptional control by A-factor of strR, the pathway-specific transcriptional activator for streptomycin biosynthesis in Streptomyces griseus. Journal of bacteriology, 2005, Volume: 187, Issue:16 Topics: 4-Butyrolactone; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Binding Sites; Deoxyribonuclease I; DNA Footprinting; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Molecular Sequence Data; Multigene Family; Mutation; Promoter Regions, Genetic; Streptomyces griseus; Streptomycin; Trans-Activators; Transcription Factors; Transcription, Genetic	2005
Three chymotrypsin genes are members of the AdpA regulon in the A-factor regulatory cascade in Streptomyces griseus. Journal of bacteriology, 2005, Volume: 187, Issue:18 Topics: 4-Butyrolactone; Bacterial Proteins; Base Sequence; Binding Sites; Chymotrypsin; DNA Footprinting; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Molecular Sequence Data; Regulon; Streptomyces griseus; Trans-Activators	2005
Streptomycin production by Streptomyces griseus can be modulated by a mechanism not associated with change in the adpA component of the A-factor cascade. Biotechnology letters, 2007, Volume: 29, Issue:1 Topics: 4-Butyrolactone; Bacterial Proteins; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Genetic Enhancement; Streptomyces griseus; Streptomycin; Trans-Activators	2007
A-factor and phosphate depletion signals are transmitted to the grixazone biosynthesis genes via the pathway-specific transcriptional activator GriR. Journal of bacteriology, 2007, Volume: 189, Issue:9 Topics: 4-Butyrolactone; Bacterial Proteins; Base Sequence; DNA, Bacterial; Electrophoretic Mobility Shift Assay; Gene Expression Regulation, Bacterial; Molecular Sequence Data; Multigene Family; Operon; Oxazines; Phosphates; Pigments, Biological; Protein Binding; Sequence Analysis, DNA; Streptomyces griseus; Trans-Activators; Transcription, Genetic	2007
The secreted signaling protein factor C triggers the A-factor response regulon in Streptomyces griseus: overlapping signaling routes. Molecular & cellular proteomics : MCP, 2007, Volume: 6, Issue:7 Topics: 4-Butyrolactone; Bacterial Proteins; Chromatography, High Pressure Liquid; Electrophoresis, Gel, Two-Dimensional; Proteome; Regulon; Signal Transduction; Streptomyces griseus; Tandem Mass Spectrometry	2007
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350. Journal of bacteriology, 2008, Volume: 190, Issue:11 Topics: 4-Butyrolactone; Base Sequence; Gene Expression Regulation, Bacterial; Genome, Bacterial; Molecular Sequence Data; Multigene Family; Oligonucleotide Array Sequence Analysis; Streptomyces; Streptomyces coelicolor; Streptomyces griseus; Streptomycin; Telomere	2008
DNA microarray analysis of global gene regulation by A-factor in Streptomyces griseus. Microbiology (Reading, England), 2009, Volume: 155, Issue:Pt 7 Topics: 4-Butyrolactone; Bacterial Proteins; Cluster Analysis; DNA, Bacterial; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Genes, Bacterial; Oligonucleotide Array Sequence Analysis; RNA, Bacterial; Streptomyces griseus; Streptomycin; Time Factors; Trans-Activators; Transcription, Genetic	2009
Characterization of Sgr3394 produced only by the A-factor-producin Streptomyces griseus IFO 13350, not by the A-factor deficient mutant. Journal of microbiology (Seoul, Korea), 2011, Volume: 49, Issue:1 Topics: 4-Butyrolactone; Amino Acid Sequence; Anthraquinones; Bacterial Proteins; Base Sequence; Binding Sites; DNA, Fungal; Electrophoretic Mobility Shift Assay; Gene Expression Profiling; Genes, Fungal; Molecular Sequence Data; Molecular Weight; Open Reading Frames; Prodigiosin; Promoter Regions, Genetic; Protein Binding; Protein Sorting Signals; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Sequence Homology, Amino Acid; Streptomyces griseus; Trans-Activators	2011
Strict regulation of morphological differentiation and secondary metabolism by a positive feedback loop between two global regulators AdpA and BldA in Streptomyces griseus. Molecular microbiology, 2011, Volume: 81, Issue:6 Topics: 4-Butyrolactone; Base Sequence; DNA-Binding Proteins; Feedback, Physiological; Gene Deletion; Gene Expression; Gene Expression Regulation, Bacterial; Models, Biological; Molecular Sequence Data; RNA, Transfer; Sequence Homology, Nucleic Acid; Streptomyces griseus; Streptomycin; Trans-Activators	2011
Structural Elucidation of Trace Components Combining GC/MS, GC/IR, DFT-Calculation and Synthesis-Salinilactones, Unprecedented Bicyclic Lactones from Salinispora Bacteria. Angewandte Chemie (International ed. in English), 2018, 11-05, Volume: 57, Issue:45 Topics: 4-Butyrolactone; Actinobacteria; Anti-Bacterial Agents; Bridged Bicyclo Compounds; Gas Chromatography-Mass Spectrometry; Lactones; Spectrophotometry, Infrared; Streptomyces	2018
Mutation in afsR Leads to A-Factor Deficiency in Streptomyces griseus B2682. Journal of molecular microbiology and biotechnology, 2018, Volume: 28, Issue:5 Topics: 4-Butyrolactone; Anti-Bacterial Agents; Bacterial Proteins; DNA-Binding Proteins; DNA, Bacterial; Gene Expression Regulation, Bacterial; Genetic Vectors; Mutation; Peptide Hydrolases; Phenotype; Streptomyces griseus; Transcription Factors; Transformation, Bacterial	2018
Analysis on coupling dynamic effect of human errors in aviation safety. Accident; analysis and prevention, 2023, Volume: 192 Topics: 4-Butyrolactone; Accidents, Aviation; Accidents, Traffic; Aviation; Humans	2023