Page last updated: 2024-09-03

a 81988 and ro 46-2005

a 81988 has been researched along with ro 46-2005 in 1 studies

Compound Research Comparison

Studies
(a 81988)
Trials
(a 81988)
Recent Studies (post-2010)
(a 81988)
Studies
(ro 46-2005)
Trials
(ro 46-2005)
Recent Studies (post-2010) (ro 46-2005)
17002601

Protein Interaction Comparison

ProteinTaxonomya 81988 (IC50)ro 46-2005 (IC50)
Endothelin receptor type BRattus norvegicus (Norway rat)1
Endothelin receptor type BHomo sapiens (human)1.1
Endothelin-1 receptorHomo sapiens (human)0.22
Endothelin-1 receptorRattus norvegicus (Norway rat)0.23
Endothelin-1 receptorSus scrofa (pig)0.16

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Calzadilla, SV; Chiou, W; Dayton, BD; Dixon, DB; Hernandez, L; Hoffman, DJ; Kester, JA; Marsh, KC; Nellans, HN; Opgenorth, TJ; von Geldern, TW; Wu-Wong, JR1

Other Studies

1 other study(ies) available for a 81988 and ro 46-2005

ArticleYear
Azole endothelin antagonists. 3. Using delta log P as a tool to improve absorption.
    Journal of medicinal chemistry, 1996, Feb-16, Volume: 39, Issue:4

    Topics: Administration, Oral; Animals; Azepines; Azoles; Drug Design; Endothelin Receptor Antagonists; Hydrogen Bonding; Indicators and Reagents; Indoles; Injections, Intravenous; Intestinal Absorption; Kinetics; Male; Metabolic Clearance Rate; Models, Biological; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptors, Endothelin; Structure-Activity Relationship

1996