a 81988 has been researched along with ro 46-2005 in 1 studies
| Studies (a 81988) | Trials (a 81988) | Recent Studies (post-2010) (a 81988) | Studies (ro 46-2005) | Trials (ro 46-2005) | Recent Studies (post-2010) (ro 46-2005) |
|---|---|---|---|---|---|
| 17 | 0 | 0 | 26 | 0 | 1 |
| Protein | Taxonomy | a 81988 (IC50) | ro 46-2005 (IC50) |
|---|---|---|---|
| Endothelin receptor type B | Rattus norvegicus (Norway rat) | 1 | |
| Endothelin receptor type B | Homo sapiens (human) | 1.1 | |
| Endothelin-1 receptor | Homo sapiens (human) | 0.22 | |
| Endothelin-1 receptor | Rattus norvegicus (Norway rat) | 0.23 | |
| Endothelin-1 receptor | Sus scrofa (pig) | 0.16 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Calzadilla, SV; Chiou, W; Dayton, BD; Dixon, DB; Hernandez, L; Hoffman, DJ; Kester, JA; Marsh, KC; Nellans, HN; Opgenorth, TJ; von Geldern, TW; Wu-Wong, JR | 1 |
1 other study(ies) available for a 81988 and ro 46-2005
| Article | Year |
|---|---|
Azole endothelin antagonists. 3. Using delta log P as a tool to improve absorption.
Topics: Administration, Oral; Animals; Azepines; Azoles; Drug Design; Endothelin Receptor Antagonists; Hydrogen Bonding; Indicators and Reagents; Indoles; Injections, Intravenous; Intestinal Absorption; Kinetics; Male; Metabolic Clearance Rate; Models, Biological; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptors, Endothelin; Structure-Activity Relationship | 1996 |