a 68930 has been researched along with sk&f-38393 in 18 studies
| Studies (a 68930) | Trials (a 68930) | Recent Studies (post-2010) (a 68930) | Studies (sk&f-38393) | Trials (sk&f-38393) | Recent Studies (post-2010) (sk&f-38393) |
|---|---|---|---|---|---|
| 63 | 2 | 19 | 2,012 | 29 | 242 |
| 63 | 2 | 19 | 20 | 0 | 3 |
| Protein | Taxonomy | a 68930 (IC50) | sk&f-38393 (IC50) |
|---|---|---|---|
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | 2.8 | |
| D | Rattus norvegicus (Norway rat) | 0.19 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 3.75 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 15 (83.33) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Asin, KE; DeNinno, MP; Kebabian, JW; MacKenzie, R; Schoenleber, R | 1 |
| Breese, GR; Criswell, HE; Jensen, KF; Johnson, KB; Mueller, RA; Simson, PE | 1 |
| Grenader, A; Healy, DP | 1 |
| Britton, DR; Curzon, P; Kebabian, JW | 1 |
| Collu, M; D'Aquila, PS; Gessa, GL; Pani, L; Serra, G | 1 |
| Drukarch, B; Jongenelen, CA; Langeveld, CH; Stoof, JC; Vermeulen, RJ; Wolters, EC | 1 |
| Benzi, M; Bertorelli, R; Consolo, S; Girotti, P; Russi, G; Zambelli, M | 1 |
| Christie, MI; Smith, GW | 1 |
| Adami, M; Ferri, N; Ongini, E; Trampus, M | 1 |
| Deveney, AM; Waddington, JL | 1 |
| Clifford, J; Croke, DT; Deveney, AM; Drago, J; Sibley, DR; Tighe, O; Waddington, JL | 1 |
| Adachi, K; Hasegawa, M; Ikeda, H; Koshikawa, N; Nakamura, S; Waddington, JL | 1 |
| Clifford, JJ; Croke, DT; Drago, J; Kinsella, A; Sibley, DR; Tighe, O; Waddington, JL | 1 |
| Croke, DT; Fienberg, AA; Grandy, DK; Kinsella, A; Koshikawa, N; Makihara, Y; Nally, RE; O'Sullivan, G; Sibley, DR; Tighe, O; Tomiyama, K; Waddington, JL; Yamamoto, H | 1 |
| Coppa-Hopman, R; Galle, J; Pimkine, D | 1 |
| D'Ovidio, F; Emala, CW; Masaki, E; Mizuta, F; Mizuta, K; Xu, D; Zhang, Y | 1 |
| Asin, KE; Britton, DR; DeNinno, MP; Kebabian, JW; Lijewski, L; MacKenzie, R; Perner, RJ; Schoenleber, R | 1 |
| Britton, DR; Kebabian, JW; MacKenzie, R; Michaelides, MR; Schoenleber, R; Thomas, S; Yamamoto, DM | 1 |
18 other study(ies) available for a 68930 and sk&f-38393
| Article | Year |
|---|---|
(1R,3S)-1-(aminomethyl)-3,4-dihydro-5,6-dihydroxy-3-phenyl-1H-2-benzopyran: a potent and selective D1 agonist.
Topics: Animals; Benzazepines; Binding, Competitive; Chromans; Dopamine Agents; Hydroxydopamines; Molecular Structure; Oxidopamine; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Stereoisomerism | 1990 |
Comparison of the D1-dopamine agonists SKF-38393 and A-68930 in neonatal 6-hydroxydopamine-lesioned rats: behavioral effects and induction of c-fos-like immunoreactivity.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Animals, Newborn; Behavior, Animal; Benzazepines; Brain Chemistry; Chromans; Dopamine Agents; Dose-Response Relationship, Drug; Female; Motor Activity; Oxidopamine; Proto-Oncogene Proteins c-fos; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Stereotyped Behavior | 1992 |
A68930 is a potent, full agonist at dopamine1 (D1) receptors in renal epithelial LLC-PK1 cells.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Benzazepines; Cells, Cultured; Chromans; Cyclic AMP; Dopamine; Dopamine Agents; Epithelial Cells; Epithelium; Fenoldopam; Kidney; Receptors, Dopamine D1 | 1992 |
Rapid reversal of denervation supersensitivity of dopamine D1 receptors by l-dopa or a novel dopamine D1 receptor agonist, A68930.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Chromans; Denervation; Dopamine Agents; Levodopa; Male; Motor Activity; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1 | 1991 |
Antidepressant-like effect of selective dopamine D1 receptor agonists in the behavioural despair animal model of depression.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Benzazepines; Chromans; Depression; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Imipramine; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Stereoisomerism | 1994 |
Dopamine D1 receptor agonists display a different intrinsic activity in rat, monkey and human astrocytes.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Astrocytes; Benzazepines; Brain; Cells, Cultured; Chromans; Cyclic AMP; Dopamine Agonists; Female; Humans; Macaca mulatta; Male; Rats; Rats, Wistar; Stereoisomerism | 1994 |
D1 and D2 dopamine receptors and the regulation of striatal acetylcholine release in vivo.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Acetylcholine; Animals; Benzazepines; Chromans; Corpus Striatum; Dextroamphetamine; Dopamine Agents; Dopamine Antagonists; Female; Microdialysis; Pargyline; Rats; Receptors, Dopamine; Secretory Rate | 1993 |
Cardiovascular and renal hemodynamic effects of A-68930 in the conscious dog: a comparison with fenoldopam.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Chromans; Consciousness; Dogs; Dopamine Agents; Fenoldopam; Hemodynamics; Kidney; Male; Receptors, Dopamine D1 | 1994 |
The dopamine D1 receptor agonists, A68930 and SKF 38393, induce arousal and suppress REM sleep in the rat.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Chromans; Dopamine Agents; Dose-Response Relationship, Drug; Grooming; Male; Rats; Rats, Sprague-Dawley; Sleep, REM; Wakefulness | 1993 |
Pharmacological characterization of behavioural responses to SK&F 83959 in relation to 'D1-like' dopamine receptors not linked to adenylyl cyclase.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclases; Animals; Behavior, Animal; Benzamides; Benzazepines; Binding, Competitive; Chromans; Dopamine Agonists; Dopamine Antagonists; Enzyme Induction; Isoquinolines; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Spiperone; Tetrahydroisoquinolines | 1995 |
Behavioral analysis of multiple D1-like dopamine receptor subtypes: new agents and studies in transgenic mice with D1A receptor knockout.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclases; Animals; Body Weight; Chromans; Dopamine Agonists; Dopamine Antagonists; Female; Grooming; Mice; Mice, Knockout; Mice, Transgenic; Polymerase Chain Reaction; Receptors, Dopamine D1 | 1998 |
SK&F 83959 and non-cyclase-coupled dopamine D1-like receptors in jaw movements via dopamine D1-like/D2-like receptor synergism.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclases; Anesthesia; Animals; Chromans; Dopamine Agonists; Drug Combinations; Drug Interactions; Jaw; Male; Muscle Contraction; Muscle, Skeletal; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine | 1999 |
Conservation of behavioural topography to dopamine D1-like receptor agonists in mutant mice lacking the D1A receptor implicates a D1-like receptor not coupled to adenylyl cyclase.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclases; Animals; Behavior, Animal; Brain; Brain Chemistry; Chromans; Dopamine Agonists; Female; Grooming; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenethylamines; Receptors, Dopamine D1; Receptors, Dopamine D2 | 1999 |
Disruption of orofacial movement topographies in congenic mutants with dopamine D5 but not D4 receptor or DARPP-32 transduction 'knockout'.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Chromans; Dopamine and cAMP-Regulated Phosphoprotein 32; Dyskinesia, Drug-Induced; Mice; Mice, Congenic; Mice, Inbred C57BL; Mice, Knockout; Receptors, Dopamine D4; Receptors, Dopamine D5; Signal Transduction | 2006 |
D1 receptor antagonist-induced long-term depression in the medial prefrontal cortex of rat, in vivo: an animal model of psychiatric hypofrontality.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Chromans; Dopamine Agonists; Dopamine Antagonists; Electrophysiology; Male; Neuronal Plasticity; Prefrontal Cortex; Rats; Rats, Long-Evans; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate | 2009 |
The dopamine D1 receptor is expressed and facilitates relaxation in airway smooth muscle.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Acetylcholine; Animals; Bronchi; Bronchoconstriction; Bronchodilator Agents; Cells, Cultured; Chromans; Dopamine; Dopamine Agonists; Guinea Pigs; Humans; Male; Models, Animal; Muscle, Smooth; Receptors, Dopamine D1; Receptors, G-Protein-Coupled | 2013 |
Synthesis and dopaminergic activity of 3-substituted 1-(aminomethyl)-3,4-dihydro-5,6-dihydroxy-1H-2-benzopyrans: characterization of an auxiliary binding region in the D1 receptor.
Topics: Adenylyl Cyclases; Animals; Binding Sites; Binding, Competitive; Carps; Chemical Phenomena; Chemistry; Chromans; Colforsin; Corpus Striatum; Cyclic AMP; Molecular Structure; Motor Activity; Pituitary Neoplasms; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Rotation; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured | 1991 |
Synthesis and pharmacological evaluation of 1-(aminomethyl)-3,4-dihydro-5-hydroxy-1H-2-benzopyrans as dopamine D1 selective ligands.
Topics: Adenylyl Cyclase Inhibitors; Chromans; Dopamine; Dopamine Antagonists; Molecular Structure; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Structure-Activity Relationship | 1991 |