Compounds > a 195773
Page last updated: 2024-09-04

a 195773 and zithromax

a 195773 has been researched along with zithromax in 9 studies

Compound Research Comparison

Studies
(a 195773)		Trials
(a 195773)		Recent Studies (post-2010)
(a 195773)		Studies
(zithromax)		Trials
(zithromax)		Recent Studies (post-2010) (zithromax)
13066,9641,2633,790

Protein Interaction Comparison

ProteinTaxonomya 195773 (IC50)zithromax (IC50)
30S ribosomal protein S6Escherichia coli K-120.3
30S ribosomal protein S7Escherichia coli K-120.3
50S ribosomal protein L15Escherichia coli K-120.3
50S ribosomal protein L10Escherichia coli K-120.3
50S ribosomal protein L11Escherichia coli K-120.3
50S ribosomal protein L7/L12Escherichia coli K-120.3
50S ribosomal protein L19Escherichia coli K-120.3
50S ribosomal protein L1Escherichia coli K-120.3
50S ribosomal protein L20Escherichia coli K-120.3
50S ribosomal protein L27Escherichia coli K-120.3
50S ribosomal protein L28Escherichia coli K-120.3
50S ribosomal protein L29Escherichia coli K-120.3
50S ribosomal protein L31Escherichia coli K-120.3
50S ribosomal protein L31 type BEscherichia coli K-120.3
50S ribosomal protein L32Escherichia coli K-120.3
50S ribosomal protein L33Escherichia coli K-120.3
50S ribosomal protein L34Escherichia coli K-120.3
50S ribosomal protein L35Escherichia coli K-120.3
50S ribosomal protein L36Escherichia coli K-120.3
30S ribosomal protein S10Escherichia coli K-120.3
30S ribosomal protein S11Escherichia coli K-120.3
30S ribosomal protein S12Escherichia coli K-120.3
30S ribosomal protein S13Escherichia coli K-120.3
30S ribosomal protein S16Escherichia coli K-120.3
30S ribosomal protein S18Escherichia coli K-120.3
30S ribosomal protein S19Escherichia coli K-120.3
30S ribosomal protein S20Escherichia coli K-120.3
30S ribosomal protein S2Escherichia coli K-120.3
30S ribosomal protein S3Escherichia coli K-120.3
30S ribosomal protein S4Escherichia coli K-120.3
30S ribosomal protein S5Escherichia coli K-120.3
30S ribosomal protein S8Escherichia coli K-120.3
30S ribosomal protein S9Escherichia coli K-120.3
50S ribosomal protein L13Escherichia coli K-120.3
50S ribosomal protein L14Escherichia coli K-120.3
50S ribosomal protein L16Escherichia coli K-120.3
50S ribosomal protein L23Escherichia coli K-120.3
30S ribosomal protein S15Escherichia coli K-120.3
50S ribosomal protein L17Escherichia coli K-120.3
50S ribosomal protein L21Escherichia coli K-120.3
50S ribosomal protein L30Escherichia coli K-120.3
50S ribosomal protein L6Escherichia coli K-120.3
30S ribosomal protein S14Escherichia coli K-120.3
30S ribosomal protein S17Escherichia coli K-120.3
30S ribosomal protein S1Escherichia coli K-120.3
50S ribosomal protein L18Escherichia coli K-120.3
50S ribosomal protein L2Escherichia coli K-120.3
50S ribosomal protein L3Escherichia coli K-120.3
50S ribosomal protein L24Escherichia coli K-120.3
50S ribosomal protein L4Escherichia coli K-120.3
50S ribosomal protein L22Escherichia coli K-120.3
50S ribosomal protein L5Escherichia coli K-120.3
30S ribosomal protein S21Escherichia coli K-120.3
50S ribosomal protein L25Escherichia coli K-120.3
50S ribosomal protein L36 2Escherichia coli K-120.3

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (33.33)29.6817
2010's6 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alder, J; Chu, DT; Clark, RF; Ewing, P; Flamm, RK; Ma, Z; Mitten, M; Nilius, AM; Or, YS; Wang, S1
Alder, J; Brazzale, A; Cao, Z; Chu, DT; Clark, RF; Ewing, P; Flamm, R; Griesgraber, G; Li, L; Ma, Z; Meulbroek, J; Mitten, M; Nemoto, PA; Nilius, AM; Or, YS; Phan, LT; Plattner, JJ; Rupp, MJ; Shortridge, VD; Wang, S; Yong, H; Zhang, S; Zhang, X; Zhong, P1
Bailey, M; Chettiath, T; Mankin, AS1
Mutak, S; Pavlović, D2
Fajdetić, A; Mutak, S; Pavlović, D1
Andreotti, D; Biondi, S; Cardullo, F; Donati, D; Lociuro, S; Mutak, S; Paio, A; Pavlović, D; Piga, E1
Kimmins, S; Mutak, S; Pavlović, D1
Cushman, M; Fan, BZ; Han, X; Kong, FS; Li, YX; Liang, JH; Lv, W; Ma, CX; Tian, JC1

Other Studies

9 other study(ies) available for a 195773 and zithromax

ArticleYear
Design, synthesis, and antimicrobial activity of 6-O-substituted ketolides active against resistant respiratory tract pathogens.
    Journal of medicinal chemistry, 2000, Mar-23, Volume: 43, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Drug Design; Drug Resistance, Microbial; Haemophilus influenzae; Lung; Lung Diseases; Macrolides; Mice; Models, Molecular; Rats; Respiratory Tract Infections; Staphylococcal Infections; Staphylococcus; Streptococcal Infections; Streptococcus; Structure-Activity Relationship

2000
Novel erythromycin derivatives with aryl groups tethered to the C-6 position are potent protein synthesis inhibitors and active against multidrug-resistant respiratory pathogens.
    Journal of medicinal chemistry, 2001, Nov-22, Volume: 44, Issue:24

    Topics: Animals; Anti-Bacterial Agents; Carbamates; Cell-Free System; Drug Resistance, Multiple; Erythromycin; Haemophilus influenzae; Ketolides; Lung; Mice; Models, Molecular; Protein Biosynthesis; Protein Synthesis Inhibitors; Rats; Respiratory Tract Infections; Ribosomes; Staphylococcus aureus; Streptococcus pneumoniae; Streptococcus pyogenes; Structure-Activity Relationship; Transcription, Genetic

2001
Induction of erm(C) expression by noninducing antibiotics.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:3

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; Drug Resistance, Bacterial; Enzyme Induction; Escherichia coli; Gene Expression Regulation, Bacterial; Ketolides; Macrolides; Methyltransferases; Microbial Sensitivity Tests; Molecular Sequence Data; Protein Conformation; Protein Sorting Signals; Ribosomes; RNA, Messenger

2008
Synthesis and structure-activity relationships of novel 8a-aza-8a-homoerythromycin A ketolides.
    Journal of medicinal chemistry, 2010, Aug-12, Volume: 53, Issue:15

    Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Erythromycin; Gram-Negative Bacteria; Gram-Positive Bacteria; Ketolides; Microbial Sensitivity Tests; Stereoisomerism; Structure-Activity Relationship

2010
Novel hybrids of 15-membered 8a- and 9a-azahomoerythromycin A ketolides and quinolones as potent antibacterials.
    Bioorganic & medicinal chemistry, 2010, Dec-15, Volume: 18, Issue:24

    Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Drug Resistance, Multiple; Erythromycin; Haemophilus influenzae; Ketolides; Microbial Sensitivity Tests; Moraxella catarrhalis; Quinolones; Staphylococcus aureus; Structure-Activity Relationship

2010
Discovery of 4''-ether linked azithromycin-quinolone hybrid series: influence of the central linker on the antibacterial activity.
    ACS medicinal chemistry letters, 2011, May-12, Volume: 2, Issue:5

    Topics:

2011
Synthesis and Structure-Activity Relationships of α-Amino-γ-lactone Ketolides: A Novel Class of Macrolide Antibiotics.
    ACS medicinal chemistry letters, 2014, Oct-09, Volume: 5, Issue:10

    Topics:

2014
Synthesis of novel 15-membered 8a-azahomoerythromycin A acylides: Consequences of structural modification at the C-3 and C-6 position on antibacterial activity.
    European journal of medicinal chemistry, 2017, Jan-05, Volume: 125

    Topics: Animals; Anti-Bacterial Agents; Biological Availability; Drug Resistance, Bacterial; Erythromycin; Humans; Macrolides; Structure-Activity Relationship

2017
Design, synthesis and structure-activity relationships of novel macrolones: Hybrids of 2-fluoro 9-oxime ketolides and carbamoyl quinolones with highly improved activity against resistant pathogens.
    European journal of medicinal chemistry, 2019, May-01, Volume: 169

    Topics: Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Design; Drug Resistance, Bacterial; Ketolides; Microbial Sensitivity Tests; Molecular Structure; Oximes; Quinolones; Streptococcus pneumoniae; Streptococcus pyogenes; Structure-Activity Relationship

2019