a 195773 has been researched along with hmr 3647 in 12 studies
| Studies (a 195773) | Trials (a 195773) | Recent Studies (post-2010) (a 195773) | Studies (hmr 3647) | Trials (hmr 3647) | Recent Studies (post-2010) (hmr 3647) |
|---|---|---|---|---|---|
| 13 | 0 | 6 | 116 | 3 | 36 |
| Protein | Taxonomy | a 195773 (IC50) | hmr 3647 (IC50) |
|---|---|---|---|
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | 7.1 | |
| Bile salt export pump | Homo sapiens (human) | 4.5 | |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | 5.8884 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 3.4674 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (33.33) | 29.6817 |
| 2010's | 8 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alder, J; Chu, DT; Clark, RF; Ewing, P; Flamm, RK; Ma, Z; Mitten, M; Nilius, AM; Or, YS; Wang, S | 1 |
| Alder, J; Brazzale, A; Cao, Z; Chu, DT; Clark, RF; Ewing, P; Flamm, R; Griesgraber, G; Li, L; Ma, Z; Meulbroek, J; Mitten, M; Nemoto, PA; Nilius, AM; Or, YS; Phan, LT; Plattner, JJ; Rupp, MJ; Shortridge, VD; Wang, S; Yong, H; Zhang, S; Zhang, X; Zhong, P | 1 |
| Akritopoulou-Zanze, I; Daly, MM; Djuric, SW; Hensey, DM; Ma, Z; Marron, TG; Nilius, AM; Phelan, KM; Stone, GG; Yong, H | 1 |
| Bailey, M; Chettiath, T; Mankin, AS | 1 |
| Mutak, S; Pavlović, D | 3 |
| Fajdetić, A; Mutak, S; Pavlović, D | 1 |
| Klepacki, D; LeTourneau, N; Mankin, A; Melman, A; Vimal, P | 1 |
| Andreotti, D; Biondi, S; Cardullo, F; Donati, D; Lociuro, S; Mutak, S; Paio, A; Pavlović, D; Piga, E | 1 |
| Kimmins, S; Mutak, S; Pavlović, D | 1 |
| Cushman, M; Fan, BZ; Han, X; Kong, FS; Li, YX; Liang, JH; Lv, W; Ma, CX; Tian, JC | 1 |
12 other study(ies) available for a 195773 and hmr 3647
| Article | Year |
|---|---|
Design, synthesis, and antimicrobial activity of 6-O-substituted ketolides active against resistant respiratory tract pathogens.
Topics: Animals; Anti-Bacterial Agents; Drug Design; Drug Resistance, Microbial; Haemophilus influenzae; Lung; Lung Diseases; Macrolides; Mice; Models, Molecular; Rats; Respiratory Tract Infections; Staphylococcal Infections; Staphylococcus; Streptococcal Infections; Streptococcus; Structure-Activity Relationship | 2000 |
Novel erythromycin derivatives with aryl groups tethered to the C-6 position are potent protein synthesis inhibitors and active against multidrug-resistant respiratory pathogens.
Topics: Animals; Anti-Bacterial Agents; Carbamates; Cell-Free System; Drug Resistance, Multiple; Erythromycin; Haemophilus influenzae; Ketolides; Lung; Mice; Models, Molecular; Protein Biosynthesis; Protein Synthesis Inhibitors; Rats; Respiratory Tract Infections; Ribosomes; Staphylococcus aureus; Streptococcus pneumoniae; Streptococcus pyogenes; Structure-Activity Relationship; Transcription, Genetic | 2001 |
Synthesis and antibacterial activity of novel bifunctional macrolides.
Topics: Anti-Bacterial Agents; Bacteria; Cell Membrane; Drug Resistance; Drug Resistance, Bacterial; Erythromycin; Macrolides; Microbial Sensitivity Tests; Structure-Activity Relationship | 2004 |
Induction of erm(C) expression by noninducing antibiotics.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Drug Resistance, Bacterial; Enzyme Induction; Escherichia coli; Gene Expression Regulation, Bacterial; Ketolides; Macrolides; Methyltransferases; Microbial Sensitivity Tests; Molecular Sequence Data; Protein Conformation; Protein Sorting Signals; Ribosomes; RNA, Messenger | 2008 |
Synthesis and structure-activity relationships of novel 8a-aza-8a-homoerythromycin A ketolides.
Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Erythromycin; Gram-Negative Bacteria; Gram-Positive Bacteria; Ketolides; Microbial Sensitivity Tests; Stereoisomerism; Structure-Activity Relationship | 2010 |
Novel hybrids of 15-membered 8a- and 9a-azahomoerythromycin A ketolides and quinolones as potent antibacterials.
Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Drug Resistance, Multiple; Erythromycin; Haemophilus influenzae; Ketolides; Microbial Sensitivity Tests; Moraxella catarrhalis; Quinolones; Staphylococcus aureus; Structure-Activity Relationship | 2010 |
Synthesis and antibacterial activity of desosamine-modified macrolide derivatives.
Topics: Amino Sugars; Anti-Bacterial Agents; Escherichia coli; Macrolides; Microbial Viability; Models, Molecular; Molecular Structure; Staphylococcus aureus; Structure-Activity Relationship | 2012 |
Discovery of 4''-ether linked azithromycin-quinolone hybrid series: influence of the central linker on the antibacterial activity.
Topics: | 2011 |
Synthesis and Structure-Activity Relationships of α-Amino-γ-lactone Ketolides: A Novel Class of Macrolide Antibiotics.
Topics: | 2014 |
Synthesis and antibacterial evaluation of novel 4″-glycyl linked quinolyl-azithromycins with potent activity against macrolide-resistant pathogens.
Topics: Anti-Bacterial Agents; Azithromycin; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Haemophilus influenzae; Microbial Sensitivity Tests; Molecular Structure; Quinolines; Streptococcus pneumoniae; Streptococcus pyogenes; Structure-Activity Relationship | 2016 |
Synthesis of novel 15-membered 8a-azahomoerythromycin A acylides: Consequences of structural modification at the C-3 and C-6 position on antibacterial activity.
Topics: Animals; Anti-Bacterial Agents; Biological Availability; Drug Resistance, Bacterial; Erythromycin; Humans; Macrolides; Structure-Activity Relationship | 2017 |
Design, synthesis and structure-activity relationships of novel macrolones: Hybrids of 2-fluoro 9-oxime ketolides and carbamoyl quinolones with highly improved activity against resistant pathogens.
Topics: Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Design; Drug Resistance, Bacterial; Ketolides; Microbial Sensitivity Tests; Molecular Structure; Oximes; Quinolones; Streptococcus pneumoniae; Streptococcus pyogenes; Structure-Activity Relationship | 2019 |