Compounds > a 195773
Page last updated: 2024-09-04

a 195773 and erythromycin

a 195773 has been researched along with erythromycin in 6 studies

Compound Research Comparison

Studies
(a 195773)		Trials
(a 195773)		Recent Studies (post-2010)
(a 195773)		Studies
(erythromycin)		Trials
(erythromycin)		Recent Studies (post-2010) (erythromycin)
130614,5241,1381,926

Protein Interaction Comparison

ProteinTaxonomya 195773 (IC50)erythromycin (IC50)
30S ribosomal protein S6Escherichia coli K-121.156
30S ribosomal protein S7Escherichia coli K-121.156
50S ribosomal protein L15Escherichia coli K-121.156
Cytochrome P450 3A4Homo sapiens (human)1.045
50S ribosomal protein L10Escherichia coli K-121.156
50S ribosomal protein L11Escherichia coli K-121.156
50S ribosomal protein L7/L12Escherichia coli K-121.156
50S ribosomal protein L19Escherichia coli K-121.156
50S ribosomal protein L1Escherichia coli K-121.156
50S ribosomal protein L20Escherichia coli K-121.156
50S ribosomal protein L27Escherichia coli K-121.156
50S ribosomal protein L28Escherichia coli K-121.156
50S ribosomal protein L29Escherichia coli K-121.156
50S ribosomal protein L31Escherichia coli K-121.156
50S ribosomal protein L31 type BEscherichia coli K-121.156
50S ribosomal protein L32Escherichia coli K-121.156
50S ribosomal protein L33Escherichia coli K-121.156
50S ribosomal protein L34Escherichia coli K-121.156
50S ribosomal protein L35Escherichia coli K-121.156
50S ribosomal protein L36Escherichia coli K-121.156
30S ribosomal protein S10Escherichia coli K-121.156
30S ribosomal protein S11Escherichia coli K-121.156
30S ribosomal protein S12Escherichia coli K-121.156
30S ribosomal protein S13Escherichia coli K-121.156
30S ribosomal protein S16Escherichia coli K-121.156
30S ribosomal protein S18Escherichia coli K-121.156
30S ribosomal protein S19Escherichia coli K-121.156
30S ribosomal protein S20Escherichia coli K-121.156
30S ribosomal protein S2Escherichia coli K-121.156
30S ribosomal protein S3Escherichia coli K-121.156
30S ribosomal protein S4Escherichia coli K-121.156
30S ribosomal protein S5Escherichia coli K-121.156
30S ribosomal protein S8Escherichia coli K-121.156
30S ribosomal protein S9Escherichia coli K-121.156
50S ribosomal protein L13Escherichia coli K-121.156
50S ribosomal protein L14Escherichia coli K-121.156
50S ribosomal protein L16Escherichia coli K-121.156
50S ribosomal protein L23Escherichia coli K-121.156
30S ribosomal protein S15Escherichia coli K-121.156
50S ribosomal protein L17Escherichia coli K-121.156
50S ribosomal protein L21Escherichia coli K-121.156
50S ribosomal protein L30Escherichia coli K-121.156
50S ribosomal protein L6Escherichia coli K-121.156
30S ribosomal protein S14Escherichia coli K-121.156
30S ribosomal protein S17Escherichia coli K-121.156
30S ribosomal protein S1Escherichia coli K-121.156
50S ribosomal protein L18Escherichia coli K-121.156
50S ribosomal protein L2Escherichia coli K-121.156
50S ribosomal protein L3Escherichia coli K-121.156
50S ribosomal protein L24Escherichia coli K-121.156
50S ribosomal protein L4Escherichia coli K-121.156
50S ribosomal protein L22Escherichia coli K-121.156
50S ribosomal protein L5Escherichia coli K-121.156
30S ribosomal protein S21Escherichia coli K-121.156
50S ribosomal protein L25Escherichia coli K-121.156
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.039
50S ribosomal protein L36 2Escherichia coli K-121.156

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (83.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alder, J; Chu, DT; Clark, RF; Ewing, P; Flamm, RK; Ma, Z; Mitten, M; Nilius, AM; Or, YS; Wang, S1
Alder, J; Brazzale, A; Cao, Z; Chu, DT; Clark, RF; Ewing, P; Flamm, R; Griesgraber, G; Li, L; Ma, Z; Meulbroek, J; Mitten, M; Nemoto, PA; Nilius, AM; Or, YS; Phan, LT; Plattner, JJ; Rupp, MJ; Shortridge, VD; Wang, S; Yong, H; Zhang, S; Zhang, X; Zhong, P1
Akritopoulou-Zanze, I; Daly, MM; Djuric, SW; Hensey, DM; Ma, Z; Marron, TG; Nilius, AM; Phelan, KM; Stone, GG; Yong, H1
Clark, RF; Djuric, SW; Gu, YG; Ma, Z; Marron, T; Marsh, K; Nilius, AM; Soni, N; Stone, GG; Yong, H1
Bailey, M; Chettiath, T; Mankin, AS1
Klepacki, D; LeTourneau, N; Mankin, A; Melman, A; Vimal, P1

Other Studies

6 other study(ies) available for a 195773 and erythromycin

ArticleYear
Design, synthesis, and antimicrobial activity of 6-O-substituted ketolides active against resistant respiratory tract pathogens.
    Journal of medicinal chemistry, 2000, Mar-23, Volume: 43, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Drug Design; Drug Resistance, Microbial; Haemophilus influenzae; Lung; Lung Diseases; Macrolides; Mice; Models, Molecular; Rats; Respiratory Tract Infections; Staphylococcal Infections; Staphylococcus; Streptococcal Infections; Streptococcus; Structure-Activity Relationship

2000
Novel erythromycin derivatives with aryl groups tethered to the C-6 position are potent protein synthesis inhibitors and active against multidrug-resistant respiratory pathogens.
    Journal of medicinal chemistry, 2001, Nov-22, Volume: 44, Issue:24

    Topics: Animals; Anti-Bacterial Agents; Carbamates; Cell-Free System; Drug Resistance, Multiple; Erythromycin; Haemophilus influenzae; Ketolides; Lung; Mice; Models, Molecular; Protein Biosynthesis; Protein Synthesis Inhibitors; Rats; Respiratory Tract Infections; Ribosomes; Staphylococcus aureus; Streptococcus pneumoniae; Streptococcus pyogenes; Structure-Activity Relationship; Transcription, Genetic

2001
Synthesis and antibacterial activity of novel bifunctional macrolides.
    Bioorganic & medicinal chemistry letters, 2004, Jul-16, Volume: 14, Issue:14

    Topics: Anti-Bacterial Agents; Bacteria; Cell Membrane; Drug Resistance; Drug Resistance, Bacterial; Erythromycin; Macrolides; Microbial Sensitivity Tests; Structure-Activity Relationship

2004
Design, synthesis and structure-activity relationships of 6-O-arylpropargyl diazalides with potent activity against multidrug-resistant Streptococcus pneumoniae.
    Bioorganic & medicinal chemistry letters, 2005, May-16, Volume: 15, Issue:10

    Topics: Anti-Bacterial Agents; Biological Availability; Drug Resistance, Microbial; Drug Resistance, Multiple; Half-Life; Microbial Sensitivity Tests; Propanols; Streptococcus pneumoniae; Structure-Activity Relationship; Tylosin

2005
Induction of erm(C) expression by noninducing antibiotics.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:3

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; Drug Resistance, Bacterial; Enzyme Induction; Escherichia coli; Gene Expression Regulation, Bacterial; Ketolides; Macrolides; Methyltransferases; Microbial Sensitivity Tests; Molecular Sequence Data; Protein Conformation; Protein Sorting Signals; Ribosomes; RNA, Messenger

2008
Synthesis and antibacterial activity of desosamine-modified macrolide derivatives.
    Bioorganic & medicinal chemistry letters, 2012, Jul-15, Volume: 22, Issue:14

    Topics: Amino Sugars; Anti-Bacterial Agents; Escherichia coli; Macrolides; Microbial Viability; Models, Molecular; Molecular Structure; Staphylococcus aureus; Structure-Activity Relationship

2012