9-methoxycamptothecin has been researched along with camptothecin in 20 studies
*Camptothecin: An alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA TOPOISOMERASES, TYPE I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity. [MeSH]
*Camptothecin: An alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA TOPOISOMERASES, TYPE I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (10.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (35.00) | 29.6817 |
| 2010's | 10 (50.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nicholas, AW; Wall, ME; Wani, MC | 1 |
| Lindley, JT; Ronman, PE; Wall, ME; Wani, MC | 1 |
| Jiang, C; Jin, W; Li, M; Lou, L; Tang, W; You, T; Zheng, C | 1 |
| Dong, MJ; Li, JJ; Lin, XT; Liu, ZF; Wang, GL; Yang, SY; Zhang, Q; Zhao, K | 1 |
| Fan, B; Li, S; Liu, Y; Shao, C; Wang, Y; Zheng, J | 1 |
| Ji, Y; Jing, L; Shao, C; Wang, Y; Zheng, J | 1 |
| DellaPenna, D; Jones, AD; Salim, V | 1 |
| Andriantsiferana, R; Cao, S; Kingston, DG; Mamisoa, A; Miller, JS; Norris, A; Radwan, MM; Rakotonandrasana, S; Rasamison, VE; Ratovoson, F | 1 |
| Eng, WK; Hecht, SM; Hoch, JM; Johnson, RK; Kingston, DG; Ma, J; Mattern, MR; Newman, DJ; Zhou, BN | 1 |
| Fulzele, DP; Pol, BB; Satdive, RK | 1 |
| Amna, T; Anand, R; Bhat, BA; Dhar, KL; Gupta, VK; Handa, G; Puri, SC; Qazi, GN; Verma, N | 1 |
| Fulzele, DP; Satdive, RK | 1 |
| Kusari, S; Spiteller, M; Zühlke, S | 1 |
| Mohana Kumar, P; Priti, V; Ramesha, BT; Ravikanth, G; Shweta, S; Spiteller, M; Uma Shaanker, R; Vasudeva, R; Zuehlke, S | 1 |
| Chayamarit, K; Chuanasa, T; Denduangboripant, J; Saito, K; Sukrong, S; Viraporn, V; Yamazaki, M | 1 |
| Bhat, V; Cooks, RG; Ifa, DR; Naik, HR; Pradeep, T; Srimany, A | 1 |
| Ao, M; Wang, H; Wu, J; Yu, L | 1 |
| Gopalakrishnan, R; Shankar, B | 1 |
| Ao, M; Bai, Y; Liu, W; Wang, H; Yu, L; Zhu, Y | 1 |
| Bai, X; Liu, J; Sun, Y; Wang, C; Wei, Y; Zhang, N | 1 |
20 other study(ies) available for 9-methoxycamptothecin and camptothecin
| Article | Year |
|---|---|
Plant antitumor agents. 23. Synthesis and antileukemic activity of camptothecin analogues.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Leukemia L1210; Solubility; Structure-Activity Relationship | 1986 |
Plant antitumor agents. 18. Synthesis and biological activity of camptothecin analogues.
Topics: Animals; Camptothecin; Cells, Cultured; Chemical Phenomena; Chemistry; Leukemia P388; Mice | 1980 |
7-Cycloalkylcamptothecin derivatives: Preparation and biological evaluation.
Topics: Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Chemistry, Pharmaceutical; Colorectal Neoplasms; Drug Design; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; Hydrolysis; Inhibitory Concentration 50; Irinotecan; Models, Chemical; Rhodamines; Structure-Activity Relationship; Topotecan | 2009 |
Simple automated radiosynthesis of 10-[11C]methoxy-20(S)-camptothecin and biodistribution in normal mice.
Topics: Animals; Automation; Camptothecin; Intestinal Mucosa; Kidney; Liver; Mice; Mice, Inbred ICR; Positron-Emission Tomography; Tissue Distribution | 2012 |
A simple HPLC method with fluorescence detection for simultaneous determination of 10-methoxycamptothecin and its metabolite 10-hydroxycamptothecin in rat liver tissue.
Topics: Animals; Calibration; Camptothecin; Chromatography, High Pressure Liquid; Fluorescence; Limit of Detection; Liver; Male; Rats; Rats, Wistar; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence; Tissue Distribution | 2015 |
Pharmacokinetics and tissue distribution study of 10-methoxycamptothecin in rats following intragastric administration.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; Biological Availability; Camptothecin; Chromatography, High Pressure Liquid; Liquid-Liquid Extraction; Male; Rats; Rats, Wistar; Tandem Mass Spectrometry; Time Factors; Tissue Distribution | 2018 |
Camptotheca acuminata 10-hydroxycamptothecin O-methyltransferase: an alkaloid biosynthetic enzyme co-opted from flavonoid metabolism.
Topics: Alkaloids; Camptotheca; Camptothecin; Chromatography, High Pressure Liquid; Flavonoids; Metabolic Networks and Pathways; Methyltransferases; Phylogeny; Plant Proteins; Transcriptome | 2018 |
Cytotoxic and other compounds from Didymochlaena truncatula from the Madagascar rain forest.
Topics: Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Dryopteridaceae; Female; Furans; Humans; Lignans; Madagascar; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Roots; Plants, Medicinal; Tumor Cells, Cultured | 2006 |
Use of COMPARE analysis to discover new natural product drugs: isolation of camptothecin and 9-methoxycamptothecin from a new source.
Topics: Algorithms; Antineoplastic Agents, Phytogenic; Camptothecin; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Spectrum Analysis; Topoisomerase I Inhibitors | 2000 |
Growth and production of camptothecin by cell suspension cultures of Nothapodytes foetida.
Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Camptothecin; Cells, Cultured; Molecular Structure; Plant Stems; Plants, Medicinal | 2001 |
Separation of 9-methoxycamptothecin and camptothecin from Nothapodytes foetida by semipreparative HPLC.
Topics: Camptothecin; Chromatography, High Pressure Liquid; Chromatography, Liquid; Magnoliopsida; Mass Spectrometry | 2005 |
Distribution of anticancer drug camptothecin in Nothapodytes foetida.
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Chromatography, High Pressure Liquid; Magnoliopsida; Plant Structures; Seeds | 2005 |
An endophytic fungus from Camptotheca acuminata that produces camptothecin and analogues.
Topics: Antineoplastic Agents, Phytogenic; Camptotheca; Camptothecin; Fusarium; Molecular Structure; Structure-Activity Relationship | 2009 |
Endophytic fungal strains of Fusarium solani, from Apodytes dimidiata E. Mey. ex Arn (Icacinaceae) produce camptothecin, 10-hydroxycamptothecin and 9-methoxycamptothecin.
Topics: Antineoplastic Agents, Phytogenic; Base Sequence; Camptothecin; DNA, Ribosomal; Fusarium; Magnoliopsida; Mycorrhizae; Trees | 2010 |
Correlation of camptothecin-producing ability and phylogenetic relationship in the genus Ophiorrhiza.
Topics: Amino Acid Sequence; Base Sequence; Camptothecin; Chloroplasts; DNA Topoisomerases, Type I; Genetic Variation; Humans; Molecular Sequence Data; Phylogeny; Plant Proteins; Rubiaceae; Sequence Alignment; Species Specificity; Thailand | 2011 |
Direct analysis of camptothecin from Nothapodytes nimmoniana by desorption electrospray ionization mass spectrometry (DESI-MS).
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Magnoliopsida; Plant Bark; Plant Leaves; Plant Stems; Spectrometry, Mass, Electrospray Ionization | 2011 |
TNFα and Fas/FasL pathways are involved in 9-Methoxycamptothecin-induced apoptosis in cancer cells with oxidative stress and G2/M cell cycle arrest.
Topics: Apoptosis; Base Sequence; Camptothecin; Cell Division; Cell Line, Tumor; DNA Primers; Fas Ligand Protein; fas Receptor; G2 Phase; Humans; Oxidative Stress; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Tumor Necrosis Factor-alpha | 2013 |
Multiple shoot cultures of Ophiorrhiza rugosa var. decumbens Deb and Mondal--a viable renewable source for the continuous production of bioactive Camptotheca alkaloids apart from stems of the parent plant of Nothapodytes foetida (Wight) Sleumer.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Camptotheca; Camptothecin; Humans; Jurkat Cells; Magnoliopsida; MCF-7 Cells; Neoplasms; Phytotherapy; Plant Extracts; Plant Shoots; Plant Somatic Embryogenesis Techniques; Plant Stems; Rubiaceae; U937 Cells | 2014 |
Topoisomerases inhibitory activities and DNA binding properties of 9-methoxycamptothecin from Nothapodytes nimmoniana (J. Graham) Mabberly.
Topics: Camptothecin; Circular Dichroism; DNA; Magnoliopsida; Molecular Docking Simulation; Topoisomerase I Inhibitors | 2019 |
The biosynthesis of camptothecin derivatives by
Topics: Camptotheca; Camptothecin; Hydrogen-Ion Concentration; Plant Roots; Seedlings | 2021 |