9-hydroxy-10,12-octadecadienoic acid and linoleic acid

9-hydroxy-10,12-octadecadienoic acid has been researched along with linoleic acid in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19903 (10.00)18.7374
1990's16 (53.33)18.2507
2000's4 (13.33)29.6817
2010's5 (16.67)24.3611
2020's2 (6.67)2.80

Authors

AuthorsStudies
Dampier, CD; Setty, BN; Stuart, MJ1
Chiang, GK; Fritsche, TR; Henderson, WR; Rashed, M; Yong, EC1
Engels, F; Kessels, GC; Nijkamp, FP; Schreurs, AJ1
Eling, TE; Glasgow, WC1
Belkner, J; Kühn, H; Moch, D; Schewe, T; Wiesner, R1
Engles, F; Henricks, PA; Nijkamp, FP; Oosthuizen, MJ; van der Linde, HJ; van Esch, B1
Buntrock, P; Kühn, H; Moch, D; Schewe, T; Schmidt, D1
Figard, PH; Kaduce, TL; Leifur, R; Spector, AA1
Kivits, GA; Nugteren, DH1
Claeys, M; Coene, MC; Herman, AG; Jouvenaz, GH; Nugteren, DH1
Guo, L; Nakagawa, Y; Ogamo, A; Ou, Z; Shinozuka, T1
Anton, R; Camacho, M; de Moragas, JM; García, M; Godessart, N; López-Belmonte, J; Vila, L1
Engels, F; Henricks, PA; Kessels, GC; Nijkamp, FP1
Jira, W; Richter, A; Spiteller, G1
Batna, A; Fuchs, C; Spiteller, G1
Gniwotta, C; Kühn, H; Morrow, JD; Roberts, LJ1
Eling, TE; Glasgow, WC; Hill, EM1
Camacho, M; Godessart, N; Vila, L1
Jira, W; Spiteller, G1
Boullier, A; Chang, MK; Glass, CK; Green, SR; Han, KH; Li, A; Quehenberger, O1
Afzal, A; Aljada, A; Browne, R; Dandona, P; Garg, R; Ghanim, H; Hamouda, W; Mohanty, P; Prabhala, A1
Aljada, A; Assian, E; Dandona, P; Garg, R; Ghanim, H; Hamouda, W; Mohanty, P1
Cahoon, EB; Kinney, AJ1
Chen, P; Green, D; Hargreaves, KM; Ruparel, S1
Bowers, DM; Browne, RW; Garofalo, JM; MacQueen, BT; Martin, LB; Mashtare, T; Masso-Welch, PA1
Baune, BT; Collier, F; Kennedy, RL; Malabu, UH; Rasalam, RR; Rush, C; Shashidhar, VM; Vangaveti, VN1
Feldstein, AE; Gao, B; Kirpich, IA; Liu, H; McClain, CJ; Miller, ME; Ramsden, CE; Schuster, S; Warner, DR1
Białek, A; Gielecińska, I; Jelińska, M; Mojska, H; Tokarz, A1
Badenhorst, P; Buckley, CD; Hussain, T; Kwon, SY; Massey, K; Nicolaou, A; Volpe, G; Watson, MA1
Colquhoun, A; Ferreira, MT; Souza, FDC1

Trials

1 trial(s) available for 9-hydroxy-10,12-octadecadienoic acid and linoleic acid

ArticleYear
Nuclear factor-kappaB suppressive and inhibitor-kappaB stimulatory effects of troglitazone in obese patients with type 2 diabetes: evidence of an antiinflammatory action?
    The Journal of clinical endocrinology and metabolism, 2001, Volume: 86, Issue:7

    Topics: Adult; Anti-Inflammatory Agents; Blood Glucose; C-Reactive Protein; Chemokine CCL2; Cholesterol; Chromans; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Humans; I-kappa B Proteins; Insulin; Intercellular Adhesion Molecule-1; Leukocytes, Mononuclear; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Male; Middle Aged; NADPH Oxidases; Neutrophils; NF-kappa B; Obesity; Phenylalanine; Phosphoproteins; Plasminogen Activator Inhibitor 1; Reactive Oxygen Species; Thiazoles; Thiazolidinediones; Triglycerides; Troglitazone; Tyrosine

2001

Other Studies

29 other study(ies) available for 9-hydroxy-10,12-octadecadienoic acid and linoleic acid

ArticleYear
1-Deamino-8 D-arginine vasopressin decreases the production of 13-hydroxyoctadecadienoic acid by endothelial cells.
    Thrombosis research, 1992, Sep-01, Volume: 67, Issue:5

    Topics: Animals; Aorta; Cattle; Cells, Cultured; Chromatography, High Pressure Liquid; Deamino Arginine Vasopressin; Dose-Response Relationship, Drug; Endothelium, Vascular; Hemostasis; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Mass Spectrometry; Platelet Adhesiveness

1992
Toxoplasma gondii stimulates the release of 13- and 9-hydroxyoctadecadienoic acids by human platelets.
    Biochemistry, 1992, Jun-16, Volume: 31, Issue:23

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Blood Platelets; Chromatography, High Pressure Liquid; Fatty Acids, Unsaturated; Gas Chromatography-Mass Spectrometry; Hydroxyeicosatetraenoic Acids; Indomethacin; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Platelet Activation; Stereoisomerism; Toxoplasma

1992
Production of arachidonic acid and linoleic acid metabolites by human bronchoalveolar lavage cells.
    Prostaglandins, 1991, Volume: 42, Issue:5

    Topics: Arachidonate 5-Lipoxygenase; Arachidonic Acid; Bronchoalveolar Lavage Fluid; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Lipoxygenase Inhibitors; Macrophages

1991
Transduction of the epidermal growth factor mitogenic signal in BALB/c 3T3 fibroblasts involves linoleic acid metabolism.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1991, Volume: 21B

    Topics: Animals; Cell Division; Cell Line; DNA; Epidermal Growth Factor; Fibroblasts; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Lipoxygenase; Mice; Mice, Inbred BALB C; Signal Transduction

1991
Mammalian lipoxygenases--are they only involved in the arachidonic acid cascade?
    Agents and actions, 1991, Volume: 32, Issue:1-2

    Topics: Animals; Arachidonate 15-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Lipoxygenase; Rabbits; Rats; Wound Healing

1991
Epithelium-derived linoleic acid metabolites modulate airway smooth muscle function.
    Agents and actions. Supplements, 1990, Volume: 31

    Topics: Animals; Epithelial Cells; Epithelium; Histamine; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Muscle Contraction; Muscle, Smooth; Trachea

1990
The linoleic acid metabolite 9DS-hydroxy-10,12(E,Z)-octadecadienoic acid is a strong proinflammatory mediator in an experimental wound healing model of the rat.
    Biomedica biochimica acta, 1990, Volume: 49, Issue:4

    Topics: Animals; Chemotaxis, Leukocyte; Fibroblasts; Foreign-Body Reaction; Granulation Tissue; Inflammation; Leukotriene B4; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Macrophages; Male; Neutrophils; Prostheses and Implants; Rats; Wound Healing

1990
Formation of 9-hydroxyoctadecadienoic acid from linoleic acid in endothelial cells.
    The Journal of biological chemistry, 1989, Apr-25, Volume: 264, Issue:12

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Aspirin; Cell Compartmentation; Cells, Cultured; Chromatography, High Pressure Liquid; Endothelium, Vascular; Epoprostenol; Fatty Acids; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Prostaglandin-Endoperoxide Synthases; Serum Albumin; Thrombin

1989
Conversion of linoleic acid and arachidonic acid by skin epidermal lipoxygenases.
    Biochimica et biophysica acta, 1987, Sep-04, Volume: 921, Issue:1

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Arachidonic Acid; Arachidonic Acids; Chromatography, High Pressure Liquid; Epidermis; Humans; Hydroxyeicosatetraenoic Acids; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Lipoxygenase; Psoriasis; Skin

1987
Characterization of monohydroxylated lipoxygenase metabolites of arachidonic and linoleic acid in rabbit peritoneal tissue.
    Biochimica et biophysica acta, 1982, Oct-14, Volume: 713, Issue:1

    Topics: Animals; Arachidonic Acids; Chemical Phenomena; Chemistry; Hydroxyeicosatetraenoic Acids; Isomerism; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Lipoxygenase; Peritoneum; Rabbits

1982
Preferential formation of the hydroperoxide of linoleic acid in choline glycerophospholipids in human erythrocytes membrane during peroxidation with an azo initiator.
    Free radical biology & medicine, 1995, Volume: 18, Issue:6

    Topics: Adult; Amidines; Chromatography, High Pressure Liquid; Erythrocyte Membrane; Fatty Acids, Unsaturated; Humans; Hydrogen Peroxide; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Lipid Peroxidation; Phosphatidylcholines; Phosphatidylethanolamines

1995
Prostaglandin H-synthase-2 is the main enzyme involved in the biosynthesis of octadecanoids from linoleic acid in human dermal fibroblasts stimulated with interleukin-1beta.
    The Journal of investigative dermatology, 1996, Volume: 107, Issue:5

    Topics: Cells, Cultured; Female; Fibroblasts; Humans; Interleukin-1; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Prostaglandin-Endoperoxide Synthases; Skin

1996
Preferential formation of 13-hydroxylinoleic acid by human peripheral blood eosinophils.
    Prostaglandins, 1996, Volume: 52, Issue:2

    Topics: Arachidonic Acid; Basophils; Eosinophils; Humans; Leukocytes; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Lymphocytes; Monocytes; Neutrophils

1996
Increased levels of lipid oxidation products in low density lipoproteins of patients suffering from rheumatoid arthritis.
    Chemistry and physics of lipids, 1997, May-30, Volume: 87, Issue:1

    Topics: Adult; Aged; Aldehydes; Arthritis, Rheumatoid; Chromatography, Gas; Female; Humans; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Lipid Peroxidation; Lipid Peroxides; Lipoproteins, LDL; Male; Mass Spectrometry; Middle Aged

1997
Lipid peroxidation in presence of ebselen.
    Chemistry and physics of lipids, 1997, Jul-14, Volume: 87, Issue:2

    Topics: Acetamides; Aldehydes; Animals; Antioxidants; Azoles; Cell Extracts; Fatty Acids; Fluoroacetates; Gas Chromatography-Mass Spectrometry; Isoindoles; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Lipid Peroxidation; Lipid Peroxides; Molecular Structure; Myocardial Infarction; Myocardium; Organoselenium Compounds; Plasmalogens; Swine; Trifluoroacetic Acid; Trimethylsilyl Compounds

1997
Prostaglandin F2-like compounds, F2-isoprostanes, are present in increased amounts in human atherosclerotic lesions.
    Arteriosclerosis, thrombosis, and vascular biology, 1997, Volume: 17, Issue:11

    Topics: Aged; Arachidonic Acid; Arteries; Arteriosclerosis; Chromatography, High Pressure Liquid; Dinoprost; Female; Humans; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Lipid Peroxidation; Lipoproteins, LDL; Male; Middle Aged; Oxidation-Reduction; Umbilical Veins

1997
Role of arachidonic acid and linoleic acid metabolism in epidermal growth factor initiated proliferation of Syrian hamster embryo fibroblasts.
    Advances in experimental medicine and biology, 1997, Volume: 400A

    Topics: Animals; Arachidonic Acid; Cell Division; Cells, Cultured; Cricetinae; Cyclooxygenase 1; Cyclooxygenase 2; Embryo, Mammalian; Epidermal Growth Factor; Fibroblasts; Isoenzymes; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Mesocricetus; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Transcription, Genetic

1997
IL-1 increases the ability of human endothelial cells to transform linoleic acid into monohydroxy-isomers and their incorporation into cell lipids.
    Advances in experimental medicine and biology, 1997, Volume: 400B

    Topics: Carbon Radioisotopes; Cells, Cultured; Endothelium, Vascular; Humans; Hydroxylation; Indomethacin; Interleukin-1; Kinetics; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Phospholipids; Radioisotope Dilution Technique; Umbilical Veins

1997
Dramatic increase of linoleic acid peroxidation products by aging, atherosclerosis, and rheumatoid arthritis.
    Advances in experimental medicine and biology, 1999, Volume: 469

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arteriosclerosis; Arthritis, Rheumatoid; Humans; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Lipid Peroxidation; Lipoproteins, LDL; Middle Aged

1999
Oxidized LDL reduces monocyte CCR2 expression through pathways involving peroxisome proliferator-activated receptor gamma.
    The Journal of clinical investigation, 2000, Volume: 106, Issue:6

    Topics: Animals; Apolipoproteins B; Arteriosclerosis; Cells, Cultured; Down-Regulation; Humans; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Lipoproteins, LDL; Mice; Monocytes; Muscle, Smooth, Vascular; Phospholipids; Receptors, CCR2; Receptors, Chemokine; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Signal Transduction; Thiazoles; Thiazolidinediones; Transcription Factors

2000
The suppressive effect of dietary restriction and weight loss in the obese on the generation of reactive oxygen species by leukocytes, lipid peroxidation, and protein carbonylation.
    The Journal of clinical endocrinology and metabolism, 2001, Volume: 86, Issue:1

    Topics: Adult; Aged; Diet, Reducing; Female; Glucose Tolerance Test; Humans; Leukocytes; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Lipid Peroxides; Male; Middle Aged; Obesity; Phenylalanine; Proteins; Reactive Oxygen Species; Thiobarbituric Acid Reactive Substances; Tyrosine; Weight Loss

2001
Dimorphecolic acid is synthesized by the coordinate activities of two divergent Delta12-oleic acid desaturases.
    The Journal of biological chemistry, 2004, Mar-26, Volume: 279, Issue:13

    Topics: Calendula; Chromatography, Gas; DNA, Complementary; Expressed Sequence Tags; Fatty Acid Desaturases; Fatty Acids; Gas Chromatography-Mass Spectrometry; Glycine max; Linoleic Acid; Linoleic Acids, Conjugated; Models, Chemical; Molecular Sequence Data; Oleic Acid; Peptides; Phylogeny; Plasmids; Saccharomyces cerevisiae; Seeds; Time Factors

2004
The cytochrome P450 inhibitor, ketoconazole, inhibits oxidized linoleic acid metabolite-mediated peripheral inflammatory pain.
    Molecular pain, 2012, Sep-24, Volume: 8

    Topics: Animals; Antibodies; Behavior, Animal; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Freund's Adjuvant; Hot Temperature; Hyperalgesia; Inflammation; Ketoconazole; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Mice; Mice, Inbred C57BL; Nociception; Oxidation-Reduction; Pain; Rats; Rats, Sprague-Dawley; TRPV Cation Channels

2012
Mouse mammary gland is refractory to the effects of ethanol after natural lactation.
    Comparative medicine, 2013, Volume: 63, Issue:1

    Topics: Adipocytes; Analysis of Variance; Animals; Body Weight; Breast Neoplasms; Chromatography, Liquid; Disease Models, Animal; Ethanol; Female; Kidney; Lactation; Linoleic Acid; Linoleic Acids, Conjugated; Liver; Mammary Glands, Animal; Mass Spectrometry; Mice; Mice, Transgenic; Organ Size; Receptor, ErbB-2; Spleen; Time Factors

2013
Hydroxyoctadecadienoic acids regulate apoptosis in human THP-1 cells in a PPARγ-dependent manner.
    Lipids, 2014, Volume: 49, Issue:12

    Topics: alpha-Linolenic Acid; Apoptosis; Caspase 3; Caspase 7; Cell Cycle Proteins; Cell Line; Cell Survival; DNA Fragmentation; Fatty Acid-Binding Proteins; Fatty Acids, Unsaturated; Gene Expression Regulation; Humans; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Monocytes; PPAR gamma; Receptors, G-Protein-Coupled; RNA, Small Interfering; Rosiglitazone; Signal Transduction; Thiazolidinediones

2014
Dietary Linoleic Acid and Its Oxidized Metabolites Exacerbate Liver Injury Caused by Ethanol via Induction of Hepatic Proinflammatory Response in Mice.
    The American journal of pathology, 2017, Volume: 187, Issue:10

    Topics: Animals; Arachidonate 15-Lipoxygenase; Binge Drinking; Body Composition; Cytokines; Dietary Fats; Disease Models, Animal; Ethanol; Inflammation; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Liver; Macrophages; Metabolome; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Oxidative Stress; RAW 264.7 Cells

2017
Impact of conjugated linoleic acid administered to rats prior and after carcinogenic agent on arachidonic and linoleic acid metabolites in serum and tumors.
    Prostaglandins, leukotrienes, and essential fatty acids, 2017, Volume: 126

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arachidonic Acid; Carcinogenesis; Carcinogens; Dinoprostone; Humans; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Neoplasms; Rats

2017
Oxidised metabolites of the omega-6 fatty acid linoleic acid activate dFOXO.
    Life science alliance, 2020, Volume: 3, Issue:2

    Topics: Animals; Animals, Genetically Modified; Cell Nucleus; Chromatin; Dietary Fats; Disease Models, Animal; Drosophila; Drosophila Proteins; Fatty Acids, Omega-3; Forkhead Box Protein O3; Forkhead Transcription Factors; Gene Expression Regulation; HeLa Cells; Humans; Inflammation; Insulin; Linoleic Acid; Linoleic Acids, Conjugated; Obesity; Protein Binding; Signal Transduction; Transcriptome; Transfection

2020
Influence of Lipoxygenase Inhibition on Glioblastoma Cell Biology.
    International journal of molecular sciences, 2020, Nov-09, Volume: 21, Issue:21

    Topics: Arachidonate 15-Lipoxygenase; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Proliferation; G2 Phase Cell Cycle Checkpoints; Glioblastoma; Glioma; Humans; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Lipoxygenase Inhibitors

2020