9-hydroxy-10,12-octadecadienoic acid has been researched along with 13-hydroxy-9,11-octadecadienoic acid in 80 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 6 (7.50) | 18.7374 |
1990's | 41 (51.25) | 18.2507 |
2000's | 12 (15.00) | 29.6817 |
2010's | 20 (25.00) | 24.3611 |
2020's | 1 (1.25) | 2.80 |
Authors | Studies |
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Dampier, CD; Setty, BN; Stuart, MJ | 1 |
Fürstenberger, G; Lehmann, WD; Stephan, M | 2 |
Chiang, GK; Fritsche, TR; Henderson, WR; Rashed, M; Yong, EC | 1 |
Engels, F; Kessels, GC; Nijkamp, FP; Schreurs, AJ | 1 |
Eling, TE; Glasgow, WC | 2 |
Baer, AN; Costello, PB; Green, FA | 2 |
Engles, F; Henricks, PA; Nijkamp, FP; Oosthuizen, MJ; van der Linde, HJ; van Esch, B | 1 |
Engels, F; Henricks, PA; Nijkamp, FP; Oosthuizen, MJ; Van Esch, B | 1 |
Buntrock, P; Kühn, H; Moch, D; Schewe, T; Schmidt, D | 1 |
Drijver, AA; Engels, F; Nijkamp, FP | 1 |
Blin, P; Daret, D; Larrue, J | 1 |
Camp, RD; Fincham, NJ | 1 |
Kivits, GA; Nugteren, DH | 1 |
Abramson, SB; Aisen, PS; Given, W; Haines, KA; Hamberg, M; Pras, M; Samuelsson, B; Serhan, C; Weissmann, G | 1 |
Hamberg, M; Samuelsson, B | 1 |
Claeys, M; Coene, MC; Herman, AG; Jouvenaz, GH; Nugteren, DH | 1 |
Guo, L; Nakagawa, Y; Ogamo, A; Ou, Z; Shinozuka, T | 1 |
Fürstenberger, G; Habenicht, AJ; Lehmann, WD; Metzger, K; Stephan, M; Wittig, U; Zalán, I | 1 |
Angres, G; Lehmann, WD; Maier, H; Metzger, K | 1 |
Cathcart, MK; Folcik, VA | 1 |
Bagheri, F; Beckman, JK; Blair, IA; Ji, C; Marnett, LJ | 1 |
Jackson, RL; Ku, G; Ohlweiler, DF; Thomas, CE | 1 |
Grøn, B; Iversen, L; Kragballe, K; Ziboh, V | 2 |
Morland, MR; Spector, AA; Stoll, LL | 1 |
Cowlen, MS; Eling, TE | 1 |
Baer, AN; Green, FA | 1 |
Callewaert, DM; Clark, KS; Reddy, RG; Spindler, SA | 2 |
Anton, R; Camacho, M; de Moragas, JM; García, M; Godessart, N; López-Belmonte, J; Vila, L | 1 |
Engels, F; Henricks, PA; Kessels, GC; Nijkamp, FP | 1 |
Blackburn, ML; Bull, AW; Johnson, JA; Watson, JT; Welsch, CW | 1 |
Jira, W; Richter, A; Spiteller, G | 1 |
Batna, A; Fuchs, C; Spiteller, G | 1 |
Gniwotta, C; Kühn, H; Morrow, JD; Roberts, LJ | 1 |
Carson, W; Jira, W; Schramm, A; Spiteller, G | 1 |
Eling, TE; Glasgow, WC; Hill, EM | 1 |
Camacho, M; Godessart, N; Vila, L | 1 |
Alvarez, JG; Chen, H; Evans, RM; Nagy, L; Tontonoz, P | 1 |
McNeill, G; Truitt, A; Vanderhoek, JY | 1 |
Carpenter, KL; Garcia-Cruset, S; Guardiola, F; Mitchinson, MJ | 1 |
Chen, NG; Feldman, D; Malloy, PJ; Reaven, GM; Sarabia, SF; Zhao, XY | 1 |
Choi, MS; Jang, MK; Park, YB | 1 |
Jira, W; Spiteller, G | 1 |
Bürger, F; Fürstenberger, G; Krieg, P; Marks, F | 1 |
Boullier, A; Chang, MK; Glass, CK; Green, SR; Han, KH; Li, A; Quehenberger, O | 1 |
Afzal, A; Aljada, A; Browne, R; Dandona, P; Garg, R; Ghanim, H; Hamouda, W; Mohanty, P; Prabhala, A | 1 |
Aljada, A; Dandona, P; Friedman, J; Garg, R; Ghanim, H; Mohanty, P | 1 |
Aljada, A; Assian, E; Dandona, P; Garg, R; Ghanim, H; Hamouda, W; Mohanty, P | 1 |
Brüne, B; Fischer, B; von Knethen, A | 1 |
Carlson, MG; Cronbach, EJ; Nelson, DM; Sadovsky, Y; Schaiff, WT; Schild, RL | 1 |
Feussner, I; Kolbe, A; Kraus, A; Wasternack, C; Weichert, H | 1 |
Agaugué, S; André, P; Coutant, F; Lotteau, V; Perrin-Cocon, L | 1 |
Garbe, LA; Hübke, H; Tressl, R | 1 |
Bentel, JM; Brownrigg, LM; Croft, KD; Dharmarajan, AM; Hampel, JK; Puddey, IB; Vignarajah, D; Yeap, BB | 1 |
Shiraki, T | 1 |
Akazawa, YO; Liu, W; Niki, E; Porter, NA; Yin, H; Yoshida, Y | 1 |
Anantharamiah, GM; Fogelman, AM; Grijalva, V; Imaizumi, S; Navab, M; Reddy, ST; Van Lenten, BJ; Wagner, AC | 1 |
Bloom, MS; Browne, RW; Goldman, LR; Mumford, SL; Perkins, NJ; Pollack, AZ; Rudra, CB; Schisterman, EF; Wactawski-Wende, J | 1 |
Chen, P; Green, D; Hargreaves, KM; Ruparel, S | 1 |
Gu, J; Kellom, M; Ramsden, CE; Rapoport, SI; Remaley, AT; Sampson, M; Soldin, SJ; Taha, AY; Yuan, ZX | 1 |
Alsalem, M; Arya, PH; Barrett, DA; Bennett, A; Chan, MS; Chapman, V; Kendall, DA; Millns, P; Wong, A | 1 |
Maghazachi, AA; Rolin, J | 1 |
Dew, DA; Luo, B; Meaney, MP; Nieman, DC; Pappan, KL; Shanely, RA | 1 |
Baune, BT; Collier, F; Kennedy, RL; Malabu, UH; Rasalam, RR; Rush, C; Shashidhar, VM; Vangaveti, VN | 1 |
Abe, H; Ishida, N; Murotomi, K; Nakajima, Y; Shichiri, M; Umeno, A; Yasunaga, M; Yoshida, Y | 1 |
Gao, L; Wang, A; Wang, B; Wang, Y; Xu, C; Zha, K; Zhang, B; Zhang, Y; Zhao, J; Zuo, C | 1 |
Chen, H; John, CS; Knagge, KJ; Meaney, MP; Nieman, DC | 1 |
Bergström, S; Bonde, M; Gouveia-Figueira, S; Lindquist, E; Magambo, J; Muhinda, C; Normark, J; Orikiiriza, J; Surowiec, I; Trygg, J | 1 |
Feldstein, AE; Gao, B; Kirpich, IA; Liu, H; McClain, CJ; Miller, ME; Ramsden, CE; Schuster, S; Warner, DR | 1 |
Białek, A; Gielecińska, I; Jelińska, M; Mojska, H; Tokarz, A | 1 |
Chiba, T; Fujishima, K; Furue, M; Hashimoto-Hachiya, A; Nakahara, T | 1 |
Ernerudh, J; Ghafouri, B; Ghafouri, N; Gouveia-Figueira, S; Håkansson, I; Nording, M; Vrethem, M | 1 |
Amicarelli, F; Cervellati, C; Cordone, V; Hayek, J; Pecorelli, A; Valacchi, G | 1 |
Habazi, D; Han, J; Mohan, C; Saxena, R; Wu, T; Ye, Y; Zhang, T | 1 |
Bian, H; Geng, Z; Liu, T; Ma, J; Sun, C; Wang, D; Xu, W; Zhang, M | 1 |
Colquhoun, A; Ferreira, MT; Souza, FDC | 1 |
2 review(s) available for 9-hydroxy-10,12-octadecadienoic acid and 13-hydroxy-9,11-octadecadienoic acid
Article | Year |
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[Activation mechanism of PPARgamma by its endogenous ligands].
Topics: Adipocytes; Cell Differentiation; Humans; Insulin Resistance; Ligands; Linoleic Acids; Linoleic Acids, Conjugated; Macrophage Activation; PPAR gamma; Prostaglandin D2 | 2007 |
Implications of chemokines, chemokine receptors, and inflammatory lipids in atherosclerosis.
Topics: Animals; Atherosclerosis; Chemokines; Dendritic Cells; Humans; Linoleic Acids; Linoleic Acids, Conjugated; Lipids; Lipoproteins, LDL; Lysophospholipids; Receptors, Chemokine; Sphingosine | 2014 |
1 trial(s) available for 9-hydroxy-10,12-octadecadienoic acid and 13-hydroxy-9,11-octadecadienoic acid
Article | Year |
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Nuclear factor-kappaB suppressive and inhibitor-kappaB stimulatory effects of troglitazone in obese patients with type 2 diabetes: evidence of an antiinflammatory action?
Topics: Adult; Anti-Inflammatory Agents; Blood Glucose; C-Reactive Protein; Chemokine CCL2; Cholesterol; Chromans; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Humans; I-kappa B Proteins; Insulin; Intercellular Adhesion Molecule-1; Leukocytes, Mononuclear; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Male; Middle Aged; NADPH Oxidases; Neutrophils; NF-kappa B; Obesity; Phenylalanine; Phosphoproteins; Plasminogen Activator Inhibitor 1; Reactive Oxygen Species; Thiazoles; Thiazolidinediones; Triglycerides; Troglitazone; Tyrosine | 2001 |
77 other study(ies) available for 9-hydroxy-10,12-octadecadienoic acid and 13-hydroxy-9,11-octadecadienoic acid
Article | Year |
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1-Deamino-8 D-arginine vasopressin decreases the production of 13-hydroxyoctadecadienoic acid by endothelial cells.
Topics: Animals; Aorta; Cattle; Cells, Cultured; Chromatography, High Pressure Liquid; Deamino Arginine Vasopressin; Dose-Response Relationship, Drug; Endothelium, Vascular; Hemostasis; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Mass Spectrometry; Platelet Adhesiveness | 1992 |
Profiling assay for lipoxygenase products of linoleic and arachidonic acid by gas chromatography-mass spectrometry.
Topics: Animals; Arachidonic Acids; Female; Gas Chromatography-Mass Spectrometry; Hydroxyeicosatetraenoic Acids; Hydroxylation; Hyperplasia; Linoleic Acids; Linoleic Acids, Conjugated; Lipoxygenase; Mice; Papilloma; Skin; Skin Neoplasms | 1992 |
Toxoplasma gondii stimulates the release of 13- and 9-hydroxyoctadecadienoic acids by human platelets.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Blood Platelets; Chromatography, High Pressure Liquid; Fatty Acids, Unsaturated; Gas Chromatography-Mass Spectrometry; Hydroxyeicosatetraenoic Acids; Indomethacin; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Platelet Activation; Stereoisomerism; Toxoplasma | 1992 |
Production of arachidonic acid and linoleic acid metabolites by human bronchoalveolar lavage cells.
Topics: Arachidonate 5-Lipoxygenase; Arachidonic Acid; Bronchoalveolar Lavage Fluid; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Lipoxygenase Inhibitors; Macrophages | 1991 |
Transduction of the epidermal growth factor mitogenic signal in BALB/c 3T3 fibroblasts involves linoleic acid metabolism.
Topics: Animals; Cell Division; Cell Line; DNA; Epidermal Growth Factor; Fibroblasts; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Lipoxygenase; Mice; Mice, Inbred BALB C; Signal Transduction | 1991 |
Stereospecificity of the hydroxyeicosatetraenoic and hydroxyoctadecadienoic acids produced by cultured bovine endothelial cells.
Topics: Animals; Cattle; Cells, Cultured; Chromatography, High Pressure Liquid; Endothelium, Vascular; Hydroxyeicosatetraenoic Acids; Indomethacin; Linoleic Acids; Linoleic Acids, Conjugated; Stereoisomerism; Substrate Specificity | 1991 |
In vivo activation of an omega-6 oxygenase in human skin.
Topics: Antithrombins; Arachidonate 15-Lipoxygenase; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Enzyme Activation; Female; Gas Chromatography-Mass Spectrometry; Humans; Linoleic Acids; Linoleic Acids, Conjugated; Lipids; Male; Skin; Stereoisomerism | 1991 |
Epithelium-derived linoleic acid metabolites modulate airway smooth muscle function.
Topics: Animals; Epithelial Cells; Epithelium; Histamine; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Muscle Contraction; Muscle, Smooth; Trachea | 1990 |
Production of arachidonic and linoleic acid metabolites by guinea pig tracheal epithelial cells.
Topics: Animals; Antithrombins; Arachidonic Acid; Arachidonic Acids; Carbon Radioisotopes; Epithelial Cells; Epithelium; Fatty Acids; Guinea Pigs; Hydroxyeicosatetraenoic Acids; Linoleic Acids; Linoleic Acids, Conjugated; Male; Perfusion; Trachea | 1990 |
The linoleic acid metabolite 9DS-hydroxy-10,12(E,Z)-octadecadienoic acid is a strong proinflammatory mediator in an experimental wound healing model of the rat.
Topics: Animals; Chemotaxis, Leukocyte; Fibroblasts; Foreign-Body Reaction; Granulation Tissue; Inflammation; Leukotriene B4; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Macrophages; Male; Neutrophils; Prostheses and Implants; Rats; Wound Healing | 1990 |
Modulation of the release of 9-hydroxy-octadecadienoic acid and other fatty acid derived mediators from guinea-pig pulmonary macrophages.
Topics: Animals; Fatty Acids; Fatty Acids, Unsaturated; Guinea Pigs; Immune Sera; Linoleic Acids; Linoleic Acids, Conjugated; Lung; Macrophages; Male | 1990 |
Synthesis of hydroxy fatty acids from linoleic acid by human blood platelets.
Topics: Arachidonate 15-Lipoxygenase; Arachidonate Lipoxygenases; Arachidonic Acids; Blood Platelets; Chromatography, High Pressure Liquid; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Kinetics; Linoleic Acids; Linoleic Acids, Conjugated; Prostaglandin-Endoperoxide Synthases | 1989 |
Inhibition of ionophore-stimulated leukotriene B4 production in human leucocytes by monohydroxy fatty acids.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Arachidonate Lipoxygenases; Calcimycin; Chromatography, High Pressure Liquid; Humans; Hydroxy Acids; Hydroxyeicosatetraenoic Acids; Leukocytes; Leukotriene B4; Linoleic Acids; Linoleic Acids, Conjugated; Lipoxygenase; Skin; Time Factors | 1985 |
Conversion of linoleic acid and arachidonic acid by skin epidermal lipoxygenases.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Arachidonic Acid; Arachidonic Acids; Chromatography, High Pressure Liquid; Epidermis; Humans; Hydroxyeicosatetraenoic Acids; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Lipoxygenase; Psoriasis; Skin | 1987 |
Circulating hydroxy fatty acids in familial Mediterranean fever.
Topics: Cell Aggregation; Familial Mediterranean Fever; Humans; Hydroxy Acids; Hydroxyeicosatetraenoic Acids; Linoleic Acids; Linoleic Acids, Conjugated; Neutrophils | 1985 |
Stereochemistry in the formation of 9-hydroxy-10,12-octadecadienoic acid and 13-hydroxy-9,11-octadecadienoic acid from linoleic acid by fatty acid cyclooxygenase.
Topics: Animals; Linoleic Acids; Linoleic Acids, Conjugated; Male; Microsomes; Prostaglandin-Endoperoxide Synthases; Seminal Vesicles; Sheep; Stereoisomerism | 1980 |
Characterization of monohydroxylated lipoxygenase metabolites of arachidonic and linoleic acid in rabbit peritoneal tissue.
Topics: Animals; Arachidonic Acids; Chemical Phenomena; Chemistry; Hydroxyeicosatetraenoic Acids; Isomerism; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Lipoxygenase; Peritoneum; Rabbits | 1982 |
Preferential formation of the hydroperoxide of linoleic acid in choline glycerophospholipids in human erythrocytes membrane during peroxidation with an azo initiator.
Topics: Adult; Amidines; Chromatography, High Pressure Liquid; Erythrocyte Membrane; Fatty Acids, Unsaturated; Humans; Hydrogen Peroxide; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Lipid Peroxidation; Phosphatidylcholines; Phosphatidylethanolamines | 1995 |
Quantitative lipoxygenase product profiling by gas chromatography negative-ion chemical ionization mass spectrometry.
Topics: Animals; Cell Line; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyeicosatetraenoic Acids; Linoleic Acids; Linoleic Acids, Conjugated; Lipoxygenase; Mice | 1995 |
Lipoxygenase products in human saliva: patients with oral cancer compared to controls.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Arachidonic Acid; Humans; Hydroxyeicosatetraenoic Acids; Linoleic Acids; Linoleic Acids, Conjugated; Lipoxygenase; Mouth Neoplasms; Parotid Gland; Saliva; Submandibular Gland | 1995 |
Predominance of esterified hydroperoxy-linoleic acid in human monocyte-oxidized LDL.
Topics: Cholesterol Esters; Esterification; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Kinetics; Linoleic Acids; Linoleic Acids, Conjugated; Lipid Peroxides; Lipoproteins, LDL; Monocytes; Oxidation-Reduction; Thiobarbituric Acid Reactive Substances | 1994 |
Phospholipid peroxidation in tumor promoter-exposed mouse skin.
Topics: Aminobenzoates; Animals; Antioxidants; Borohydrides; Calcimycin; Chlorobenzoates; Chromatography, High Pressure Liquid; Cinnamates; Epidermis; Female; Fluocinolone Acetonide; Free Radicals; Gas Chromatography-Mass Spectrometry; Hydrolysis; Linoleic Acids; Linoleic Acids, Conjugated; Lipid Peroxidation; Lipoxygenase Inhibitors; Masoprocol; Mice; Mice, Inbred SENCAR; ortho-Aminobenzoates; Phospholipases A; Phospholipases A2; Phospholipids; Pregnatrienes; Stereoisomerism; Tetradecanoylphorbol Acetate; Thiobarbituric Acid Reactive Substances | 1994 |
Multiple lipid oxidation products in low density lipoproteins induce interleukin-1 beta release from human blood mononuclear cells.
Topics: Aldehydes; Copper; Dialysis; Humans; Interleukin-1; Leukocytes, Mononuclear; Linoleic Acids; Linoleic Acids, Conjugated; Lipid Peroxidation; Lipoproteins, LDL; Oxidation-Reduction; Thiobarbituric Acid Reactive Substances | 1994 |
Distribution of monohydroxy fatty acids in specific human epidermal phospholipids.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Epidermis; Fatty Acids, Unsaturated; Humans; Hydroxyeicosatetraenoic Acids; Linoleic Acids; Linoleic Acids, Conjugated; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phospholipids | 1993 |
13-HODE increases intracellular calcium in vascular smooth muscle cells.
Topics: Animals; Calcium; Cells, Cultured; Cyclic GMP; Hydroxyeicosatetraenoic Acids; Intracellular Membranes; Linoleic Acids; Linoleic Acids, Conjugated; Muscle, Smooth, Vascular; Swine | 1994 |
Monohydroxy fatty acids esterified to phospholipids are decreased in lesional psoriatic skin.
Topics: Esters; Fatty Acids; Humans; Hydroxyeicosatetraenoic Acids; Linoleic Acids; Linoleic Acids, Conjugated; Phospholipids; Psoriasis; Skin | 1993 |
Effects of prostaglandins and hydroxyoctadecadienoic acid on epidermal growth factor-dependent DNA synthesis and c-myc proto-oncogene expression in Syrian hamster embryo cells.
Topics: Animals; Cell Line; Cricetinae; Cricetulus; DNA; Epidermal Growth Factor; Genes, myc; Linoleic Acids; Linoleic Acids, Conjugated; Prostaglandins; Proto-Oncogene Proteins c-myc | 1993 |
Cyclooxygenase activity of cultured human mesothelial cells.
Topics: Cells, Cultured; Chromatography, High Pressure Liquid; Epithelial Cells; Epithelium; Esterification; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Kinetics; Linoleic Acids; Linoleic Acids, Conjugated; Oxygen; Prostaglandin-Endoperoxide Synthases; Stereoisomerism | 1993 |
Significance and immunoassay of 9- and 13-hydroxyoctadecadienoic acids.
Topics: Animals; Antibodies; Cross Reactions; Enzyme-Linked Immunosorbent Assay; Goats; Linoleic Acids; Linoleic Acids, Conjugated; Sensitivity and Specificity | 1996 |
Prostaglandin H-synthase-2 is the main enzyme involved in the biosynthesis of octadecanoids from linoleic acid in human dermal fibroblasts stimulated with interleukin-1beta.
Topics: Cells, Cultured; Female; Fibroblasts; Humans; Interleukin-1; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Prostaglandin-Endoperoxide Synthases; Skin | 1996 |
Preferential formation of 13-hydroxylinoleic acid by human peripheral blood eosinophils.
Topics: Arachidonic Acid; Basophils; Eosinophils; Humans; Leukocytes; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Lymphocytes; Monocytes; Neutrophils | 1996 |
Separation and quantitation of linoleic acid oxidation products in mammary gland tissue from mice fed low- and high-fat diets.
Topics: Analysis of Variance; Animals; Dietary Fats; Energy Intake; Female; Gas Chromatography-Mass Spectrometry; Linoleic Acids; Linoleic Acids, Conjugated; Mammary Glands, Animal; Mice; Oxidation-Reduction; Rats | 1997 |
Increased levels of lipid oxidation products in low density lipoproteins of patients suffering from rheumatoid arthritis.
Topics: Adult; Aged; Aldehydes; Arthritis, Rheumatoid; Chromatography, Gas; Female; Humans; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Lipid Peroxidation; Lipid Peroxides; Lipoproteins, LDL; Male; Mass Spectrometry; Middle Aged | 1997 |
Lipid peroxidation in presence of ebselen.
Topics: Acetamides; Aldehydes; Animals; Antioxidants; Azoles; Cell Extracts; Fatty Acids; Fluoroacetates; Gas Chromatography-Mass Spectrometry; Isoindoles; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Lipid Peroxidation; Lipid Peroxides; Molecular Structure; Myocardial Infarction; Myocardium; Organoselenium Compounds; Plasmalogens; Swine; Trifluoroacetic Acid; Trimethylsilyl Compounds | 1997 |
Role and detection of 9 and 13-hydroxyoctadecadienoic acids.
Topics: Animals; Body Fluids; Enzyme-Linked Immunosorbent Assay; Goats; Humans; Immune Sera; Linoleic Acids; Linoleic Acids, Conjugated | 1997 |
Prostaglandin F2-like compounds, F2-isoprostanes, are present in increased amounts in human atherosclerotic lesions.
Topics: Aged; Arachidonic Acid; Arteries; Arteriosclerosis; Chromatography, High Pressure Liquid; Dinoprost; Female; Humans; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Lipid Peroxidation; Lipoproteins, LDL; Male; Middle Aged; Oxidation-Reduction; Umbilical Veins | 1997 |
Strong increase in hydroxy fatty acids derived from linoleic acid in human low density lipoproteins of atherosclerotic patients.
Topics: Adult; Arteriosclerosis; Female; Humans; Linoleic Acids; Linoleic Acids, Conjugated; Lipid Peroxides; Lipoproteins, LDL; Male; Middle Aged; Ultrasonography | 1998 |
Monohydroxylated fatty acids in mouse epidermis papilloma quantification and stereochemical characterization.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Chromatography, High Pressure Liquid; Hydroxyeicosatetraenoic Acids; Linoleic Acids; Linoleic Acids, Conjugated; Mice; Papilloma; Skin Neoplasms | 1997 |
Role of arachidonic acid and linoleic acid metabolism in epidermal growth factor initiated proliferation of Syrian hamster embryo fibroblasts.
Topics: Animals; Arachidonic Acid; Cell Division; Cells, Cultured; Cricetinae; Cyclooxygenase 1; Cyclooxygenase 2; Embryo, Mammalian; Epidermal Growth Factor; Fibroblasts; Isoenzymes; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Mesocricetus; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Transcription, Genetic | 1997 |
Structural requirements for enhancement of EGF-dependent DNA synthesis by oxygenated metabolites of linoleic acid.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Cell Division; Cell Line; Cricetinae; DNA; DNA Replication; Embryo, Mammalian; Epidermal Growth Factor; Hydroxyeicosatetraenoic Acids; Linoleic Acids; Linoleic Acids, Conjugated; Mesocricetus; Oxidation-Reduction; Thymidine | 1997 |
IL-1 increases the ability of human endothelial cells to transform linoleic acid into monohydroxy-isomers and their incorporation into cell lipids.
Topics: Carbon Radioisotopes; Cells, Cultured; Endothelium, Vascular; Humans; Hydroxylation; Indomethacin; Interleukin-1; Kinetics; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Phospholipids; Radioisotope Dilution Technique; Umbilical Veins | 1997 |
Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma.
Topics: Animals; CD36 Antigens; Cell Differentiation; Cells, Cultured; Dimerization; Fatty Acids, Unsaturated; Humans; Ligands; Linoleic Acids; Linoleic Acids, Conjugated; Lipopolysaccharide Receptors; Lipoproteins, LDL; Macrophages; Membrane Proteins; Monocytes; Oxidation-Reduction; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Receptors, Immunologic; Receptors, Lipoprotein; Receptors, Retinoic Acid; Receptors, Scavenger; Recombinant Fusion Proteins; Retinoid X Receptors; Scavenger Receptors, Class B; Signal Transduction; Transcription Factors; Transcriptional Activation | 1998 |
Antiplatelet effects of conjugated linoleic acid isomers.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Arachidonic Acid; Blood Platelets; Dietary Fats, Unsaturated; Humans; Isomerism; Linoleic Acids; Linoleic Acids, Conjugated; Platelet Aggregation Inhibitors; Thromboxane B2 | 1999 |
Oxysterols in cap and core of human advanced atherosclerotic lesions.
Topics: Aged; Aged, 80 and over; Arteriosclerosis; Cholesterol; Chromatography, Gas; Fatty Acids; Humans; Hydroxycholesterols; Linoleic Acids; Linoleic Acids, Conjugated; Lipid Metabolism; Lipids; Male; Mass Spectrometry | 1999 |
PPARgamma agonists enhance human vascular endothelial adhesiveness by increasing ICAM-1 expression.
Topics: Antioxidants; Cell Adhesion; Cell Line, Transformed; Chromans; DNA-Binding Proteins; Endothelium, Vascular; Gene Expression Regulation; Humans; Intercellular Adhesion Molecule-1; Linoleic Acids; Linoleic Acids, Conjugated; Lipopolysaccharides; Lipoproteins, LDL; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Thiazoles; Thiazolidinediones; Transcription Factors; Transfection; Troglitazone; Tumor Necrosis Factor-alpha; Umbilical Veins | 1999 |
Regulation of ferritin light chain gene expression by oxidized low-density lipoproteins in human monocytic THP-1 cells.
Topics: Apoferritins; Base Sequence; Cell Differentiation; Cell Line; DNA Primers; Ferritins; Gene Expression Regulation; Humans; Hydroxycholesterols; Ligands; Linoleic Acids; Linoleic Acids, Conjugated; Lipoproteins, LDL; Monocytes; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors | 1999 |
Dramatic increase of linoleic acid peroxidation products by aging, atherosclerosis, and rheumatoid arthritis.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arteriosclerosis; Arthritis, Rheumatoid; Humans; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Lipid Peroxidation; Lipoproteins, LDL; Middle Aged | 1999 |
Positional- and stereo-selectivity of fatty acid oxygenation catalysed by mouse (12S)-lipoxygenase isoenzymes.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonate 12-Lipoxygenase; Arachidonic Acid; Blood Platelets; Cell Line; Epidermis; Humans; Isoenzymes; Kinetics; Leukocytes; Linoleic Acids; Linoleic Acids, Conjugated; Mice; Models, Chemical; Recombinant Proteins; Stereoisomerism; Substrate Specificity; Transfection | 2000 |
Oxidized LDL reduces monocyte CCR2 expression through pathways involving peroxisome proliferator-activated receptor gamma.
Topics: Animals; Apolipoproteins B; Arteriosclerosis; Cells, Cultured; Down-Regulation; Humans; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Lipoproteins, LDL; Mice; Monocytes; Muscle, Smooth, Vascular; Phospholipids; Receptors, CCR2; Receptors, Chemokine; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Signal Transduction; Thiazoles; Thiazolidinediones; Transcription Factors | 2000 |
The suppressive effect of dietary restriction and weight loss in the obese on the generation of reactive oxygen species by leukocytes, lipid peroxidation, and protein carbonylation.
Topics: Adult; Aged; Diet, Reducing; Female; Glucose Tolerance Test; Humans; Leukocytes; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Lipid Peroxides; Male; Middle Aged; Obesity; Phenylalanine; Proteins; Reactive Oxygen Species; Thiobarbituric Acid Reactive Substances; Tyrosine; Weight Loss | 2001 |
Troglitazone reduces the expression of PPARgamma while stimulating that of PPARalpha in mononuclear cells in obese subjects.
Topics: Adult; Antioxidants; Blood Glucose; Blotting, Western; Chromans; Female; Humans; Insulin; Leukocytes, Mononuclear; Linoleic Acids; Linoleic Acids, Conjugated; Lipids; Male; Middle Aged; Obesity; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 2001 |
Dualism of oxidized lipoproteins in provoking and attenuating the oxidative burst in macrophages: role of peroxisome proliferator-activated receptor-gamma.
Topics: Animals; Cell Line; Cells, Cultured; Humans; Linoleic Acids; Linoleic Acids, Conjugated; Lipoproteins, LDL; Macrophage Activation; Macrophages; Mice; Monocytes; Reactive Oxygen Species; Receptors, Cytoplasmic and Nuclear; Respiratory Burst; Thiazoles; Thiazolidinediones; Transcription Factors; U937 Cells | 2002 |
The activity of PPAR gamma in primary human trophoblasts is enhanced by oxidized lipids.
Topics: Cell Differentiation; Cells, Cultured; Humans; Linoleic Acids; Linoleic Acids, Conjugated; Progesterone; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Trophoblasts | 2002 |
Metabolic profiling of oxylipins in germinating cucumber seedlings--lipoxygenase-dependent degradation of triacylglycerols and biosynthesis of volatile aldehydes.
Topics: Aldehydes; Cotyledon; Cucumis sativus; Cyclopentanes; Fatty Acids, Unsaturated; Germination; Intramolecular Oxidoreductases; Isoenzymes; Linoleic Acids; Linoleic Acids, Conjugated; Lipid Peroxides; Lipoxygenase; Oxylipins; Seeds; Time Factors; Triglycerides; Volatilization | 2002 |
Sensing environmental lipids by dendritic cell modulates its function.
Topics: Acute-Phase Proteins; Cell Differentiation; Dendritic Cells; DNA-Binding Proteins; Fat Emulsions, Intravenous; Growth Inhibitors; Humans; Hydroxyeicosatetraenoic Acids; Interferon-gamma; Ligands; Linoleic Acids; Linoleic Acids, Conjugated; Lipoproteins, LDL; Lysophosphatidylcholines; Oxidation-Reduction; Receptors, Cytoplasmic and Nuclear; Signal Transduction; T-Lymphocytes; Thiazolidinediones; Transcription Factors | 2004 |
Characterization and quantification of free and esterified 9- and 13-hydroxyoctadecadienoic acids (HODE) in barley, germinating barley, and finished malt.
Topics: Chromatography, High Pressure Liquid; Edible Grain; Esterification; Gas Chromatography-Mass Spectrometry; Germination; Hordeum; Linoleic Acids; Linoleic Acids, Conjugated; Seeds; Stereoisomerism | 2005 |
Differential modulation of cell cycle, apoptosis and PPARgamma2 gene expression by PPARgamma agonists ciglitazone and 9-hydroxyoctadecadienoic acid in monocytic cells.
Topics: Anilides; Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Cycle Proteins; Cell Differentiation; Cell Line; Cell Survival; Gene Expression; Humans; Hypoglycemic Agents; Linoleic Acids; Linoleic Acids, Conjugated; Monocytes; PPAR gamma; Thiazolidinediones; Transcription Factors; U937 Cells | 2006 |
Ex vivo oxidation in tissue and plasma assays of hydroxyoctadecadienoates: Z,E/E,E stereoisomer ratios.
Topics: Animals; Borohydrides; Chromatography, High Pressure Liquid; Female; Gas Chromatography-Mass Spectrometry; Linoleic Acids; Linoleic Acids, Conjugated; Mice; Mice, Inbred BALB C; Organophosphorus Compounds; Oxidation-Reduction; Stereoisomerism; Tandem Mass Spectrometry | 2010 |
L-4F differentially alters plasma levels of oxidized fatty acids resulting in more anti-inflammatory HDL in mice.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Anti-Inflammatory Agents; Apolipoproteins E; Atherosclerosis; Chromatography, Liquid; Enzyme-Linked Immunosorbent Assay; Fatty Acids; Female; Hydroxyeicosatetraenoic Acids; Injections, Subcutaneous; Linoleic Acids; Linoleic Acids, Conjugated; Lipid Peroxides; Lipoproteins, HDL; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Oxidation-Reduction; Peptides; Species Specificity; Tandem Mass Spectrometry; Time Factors; Up-Regulation | 2010 |
Relation of blood cadmium, lead, and mercury levels to biomarkers of lipid peroxidation in premenopausal women.
Topics: Adolescent; Adult; Animals; Biomarkers; Cadmium; Diet; Female; Fishes; Humans; Isoprostanes; Lead; Linear Models; Linoleic Acids; Linoleic Acids, Conjugated; Lipid Peroxidation; Menstrual Cycle; Mercury; Thiobarbituric Acid Reactive Substances; Young Adult | 2012 |
The cytochrome P450 inhibitor, ketoconazole, inhibits oxidized linoleic acid metabolite-mediated peripheral inflammatory pain.
Topics: Animals; Antibodies; Behavior, Animal; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Freund's Adjuvant; Hot Temperature; Hyperalgesia; Inflammation; Ketoconazole; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Mice; Mice, Inbred C57BL; Nociception; Oxidation-Reduction; Pain; Rats; Rats, Sprague-Dawley; TRPV Cation Channels | 2012 |
Identification and profiling of targeted oxidized linoleic acid metabolites in rat plasma by quadrupole time-of-flight mass spectrometry.
Topics: Animals; Chromatography, Liquid; Limit of Detection; Linoleic Acids; Linoleic Acids, Conjugated; Linolenic Acids; Rats; Reproducibility of Results; Tandem Mass Spectrometry | 2013 |
The contribution of the endogenous TRPV1 ligands 9-HODE and 13-HODE to nociceptive processing and their role in peripheral inflammatory pain mechanisms.
Topics: Animals; Arachidonate 15-Lipoxygenase; Disease Models, Animal; Fluorenes; Ganglia, Spinal; Inflammation; Linoleic Acids; Linoleic Acids, Conjugated; Male; Mice; Pain; Rats, Sprague-Dawley; TRPV Cation Channels | 2013 |
Metabolomics approach to assessing plasma 13- and 9-hydroxy-octadecadienoic acid and linoleic acid metabolite responses to 75-km cycling.
Topics: Adult; Bicycling; Biomarkers; Chromatography, High Pressure Liquid; Cytokines; Energy Metabolism; F2-Isoprostanes; Gas Chromatography-Mass Spectrometry; Humans; Inflammation Mediators; Linoleic Acids; Linoleic Acids, Conjugated; Male; Metabolomics; Middle Aged; Oxidation-Reduction; Oxidative Stress; Physical Exertion; Tandem Mass Spectrometry; Time Factors | 2014 |
Hydroxyoctadecadienoic acids regulate apoptosis in human THP-1 cells in a PPARγ-dependent manner.
Topics: alpha-Linolenic Acid; Apoptosis; Caspase 3; Caspase 7; Cell Cycle Proteins; Cell Line; Cell Survival; DNA Fragmentation; Fatty Acid-Binding Proteins; Fatty Acids, Unsaturated; Gene Expression Regulation; Humans; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Monocytes; PPAR gamma; Receptors, G-Protein-Coupled; RNA, Small Interfering; Rosiglitazone; Signal Transduction; Thiazolidinediones | 2014 |
Switching from singlet-oxygen-mediated oxidation to free-radical-mediated oxidation in the pathogenesis of type 2 diabetes in model mouse.
Topics: Animals; Biomarkers; Diabetes Mellitus, Type 2; Disease Models, Animal; Free Radicals; Glucose Intolerance; Insulin Resistance; Linoleic Acids; Linoleic Acids, Conjugated; Male; Mice; Mice, Inbred Strains; Mice, Obese; Oxidative Stress; Singlet Oxygen | 2015 |
LDL in patients with subclinical hypothyroidism shows increased lipid peroxidation.
Topics: Asymptomatic Diseases; Atherosclerosis; Body Mass Index; Carotid Intima-Media Thickness; Female; Humans; Hydroxyeicosatetraenoic Acids; Hypothyroidism; Linoleic Acids; Linoleic Acids, Conjugated; Lipid Peroxidation; Lipoproteins, LDL; Male; Middle Aged; Oxidative Stress; Risk; Thyroxine | 2015 |
9- and 13-Hydroxy-octadecadienoic acids (9+13 HODE) are inversely related to granulocyte colony stimulating factor and IL-6 in runners after 2h running.
Topics: Adult; C-Reactive Protein; Creatine Kinase; Cytokines; Female; Granulocyte Colony-Stimulating Factor; Humans; Inflammation; Interleukin-6; Linoleic Acids; Linoleic Acids, Conjugated; Male; Middle Aged; Myalgia; Myoglobin; Oxidative Stress; Running; Young Adult | 2016 |
The oxylipin and endocannabidome responses in acute phase Plasmodium falciparum malaria in children.
Topics: Arachidonate 5-Lipoxygenase; Biomarkers; Child; Child, Preschool; Cytochrome P-450 Enzyme System; Endocannabinoids; Female; Humans; Infant; Linoleic Acids; Linoleic Acids, Conjugated; Linolenic Acids; Malaria; Malaria, Falciparum; Male; Multivariate Analysis; Oxylipins; Plasmodium falciparum; Rwanda | 2017 |
Dietary Linoleic Acid and Its Oxidized Metabolites Exacerbate Liver Injury Caused by Ethanol via Induction of Hepatic Proinflammatory Response in Mice.
Topics: Animals; Arachidonate 15-Lipoxygenase; Binge Drinking; Body Composition; Cytokines; Dietary Fats; Disease Models, Animal; Ethanol; Inflammation; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Liver; Macrophages; Metabolome; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Oxidative Stress; RAW 264.7 Cells | 2017 |
Impact of conjugated linoleic acid administered to rats prior and after carcinogenic agent on arachidonic and linoleic acid metabolites in serum and tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arachidonic Acid; Carcinogenesis; Carcinogens; Dinoprostone; Humans; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Neoplasms; Rats | 2017 |
Epidermal barrier disruption by 9-hydroxy-10E,12Z-octadecadienoic acid in human keratinocytes.
Topics: Cell Line; Electric Impedance; Epidermal Cells; Epidermis; Humans; Keratinocytes; Linoleic Acids; Linoleic Acids, Conjugated | 2018 |
Oxylipins in cerebrospinal fluid in clinically isolated syndrome and relapsing remitting multiple sclerosis.
Topics: Adult; Biomarkers; Chromatography, Liquid; Demyelinating Diseases; Female; Humans; Linoleic Acids; Linoleic Acids, Conjugated; Longitudinal Studies; Male; Multiple Sclerosis, Relapsing-Remitting; Oxylipins; Prospective Studies; Tandem Mass Spectrometry; Young Adult | 2018 |
13-HODE, 9-HODE and ALOX15 as potential players in Rett syndrome OxInflammation.
Topics: Adolescent; Adult; Arachidonate 15-Lipoxygenase; Case-Control Studies; Child; Female; Humans; Inflammation; Leukocytes, Mononuclear; Linoleic Acids; Linoleic Acids, Conjugated; Male; Rett Syndrome; Young Adult | 2019 |
Elevated oxidized lipids, anti-lipid autoantibodies and oxidized lipid immune complexes in active SLE.
Topics: Autoantibodies; Case-Control Studies; Complement C3; Complement C4; DNA; Humans; Immunoglobulin G; Immunoglobulin M; Linoleic Acids; Linoleic Acids, Conjugated; Lipoproteins, LDL; Lupus Erythematosus, Systemic; Malondialdehyde; Phospholipid Ethers; Severity of Illness Index | 2019 |
Changes of hydroxyl-linoleic acids during Chinese-style sausage processing and their relationships with lipids oxidation.
Topics: China; Fatty Acids, Unsaturated; Food Handling; Linoleic Acids; Linoleic Acids, Conjugated; Lipid Peroxidation; Lipoxygenases; Meat Products | 2019 |
Influence of Lipoxygenase Inhibition on Glioblastoma Cell Biology.
Topics: Arachidonate 15-Lipoxygenase; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Proliferation; G2 Phase Cell Cycle Checkpoints; Glioblastoma; Glioma; Humans; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Lipoxygenase Inhibitors | 2020 |