9-ethylguanine has been researched along with 4-cymene* in 1 studies
1 other study(ies) available for 9-ethylguanine and 4-cymene
| Article | Year |
|---|---|
Ruthenium(ii) p-cymene complexes of a benzimidazole-based ligand capable of VEGFR2 inhibition: hydrolysis, reactivity and cytotoxicity studies.
The design of Ru or other metal-based anticancer agents may achieve better and faster optimization if the ligands used are also designed to have standalone functions. In this scenario, even after dissociation from the metal complex under adverse conditions, the ligand would have anti-cancer properties. In our work, we have generated a bispyrazole-containing benzimidazole ligand with potency against vascular endothelial growth factor receptor 2 (VEGFR2), which is known to have roles in vasculogenesis/angiogenesis. This ligand was used to obtain ternary Ru(ii) p-cymene complexes with the formulations [(η Topics: Antineoplastic Agents; Cell Line, Tumor; Cymenes; Drug Stability; Glutathione; Guanine; Humans; Hydrolysis; Ligands; Molecular Docking Simulation; Monoterpenes; Organometallic Compounds; Protein Conformation; Ruthenium; Vascular Endothelial Growth Factor Receptor-2 | 2017 |