9-deazaadenosine and phosphonic-acid

9-deazaadenosine has been researched along with phosphonic-acid* in 1 studies

Other Studies

1 other study(ies) available for 9-deazaadenosine and phosphonic-acid

ArticleYear
The first synthesis of 4'-branched 5'-deoxycarbocyclic 9-deazaadenosine and phosphonic acids as antiviral agents.
    Nucleosides, nucleotides & nucleic acids, 2015, Volume: 34, Issue:3

    The first synthetic route to 4'-trifluoromethylated 5'-deoxycarbocyclic-9-deazaadenosine analog and its phosphonic acid derivatives was described from α-trifluoromethyl-α,β-unsaturated ester. The C-C bond connection between cyclopentane and base moiety was accomplished using Knoevenagel type condensation from ketone derivative 11. Synthesized nucleoside and phosphonic acid analogs were tested for anti-HIV activity as well as cytotoxicity.

    Topics: Anti-HIV Agents; Antiviral Agents; Cells, Cultured; HIV-1; Humans; Microbial Sensitivity Tests; Phosphorous Acids; Tubercidin

2015