9-deazaadenosine has been researched along with phosphonic-acid* in 1 studies
1 other study(ies) available for 9-deazaadenosine and phosphonic-acid
Article | Year |
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The first synthesis of 4'-branched 5'-deoxycarbocyclic 9-deazaadenosine and phosphonic acids as antiviral agents.
The first synthetic route to 4'-trifluoromethylated 5'-deoxycarbocyclic-9-deazaadenosine analog and its phosphonic acid derivatives was described from α-trifluoromethyl-α,β-unsaturated ester. The C-C bond connection between cyclopentane and base moiety was accomplished using Knoevenagel type condensation from ketone derivative 11. Synthesized nucleoside and phosphonic acid analogs were tested for anti-HIV activity as well as cytotoxicity. Topics: Anti-HIV Agents; Antiviral Agents; Cells, Cultured; HIV-1; Humans; Microbial Sensitivity Tests; Phosphorous Acids; Tubercidin | 2015 |