9,10-dimethyl-1,2-benzanthracene has been researched along with tamoxifen in 134 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 62 (46.27) | 18.7374 |
| 1990's | 28 (20.90) | 18.2507 |
| 2000's | 22 (16.42) | 29.6817 |
| 2010's | 20 (14.93) | 24.3611 |
| 2020's | 2 (1.49) | 2.80 |
| Authors | Studies |
|---|---|
| André, J; Garcia, M; Humeau, C; Rochefort, H; Vic, P | 1 |
| Dix, CJ; Jordan, VC | 1 |
| Dowse, LJ; Jordan, VC | 1 |
| Manni, A; Pearson, OH; Trujillo, JE | 1 |
| Davies, P; Griffiths, K; Nicholson, RI | 2 |
| Fiebig, HH; Schmähl, D | 2 |
| Jordan, VC; Koerner, S | 1 |
| Golder, MP; Nicholson, RI | 1 |
| Jordan, VC | 4 |
| Davies, P; Golder, MP; Griffiths, K; Nicholson, RI | 1 |
| Ebert, K; Knuppen, R; Michna, H; Vollmer, G | 1 |
| Kosaka, A; Yamashita, A | 1 |
| Fendl, KC; Zimniski, SJ | 1 |
| Kawamura, I; Kohsaka, M; Kondo, N; Mizota, T; Shimomura, K | 1 |
| Horiuchi, R; Iino, Y; Owada, S; Sugamata, N; Tago, T; Yoshida, M | 1 |
| Iino, Y; Izuo, M; Ogawa, T; Takikawa, H; Yoshida, M | 1 |
| Hussain, SP; Jannu, LN; Kumari, MV; Rao, AR | 1 |
| Komaki, K; Konishi, N; Monden, Y; Mori, T; Morimoto, T; Sasa, M; Tanaka, T; Yamakawa, T; Yamamoto, H | 1 |
| di Salle, E; Ornati, G; Zaccheo, T | 1 |
| Grönroos, M; Kangas, L | 1 |
| Cantell, K; Kangas, L; Schellekens, H | 1 |
| Hayashi, K; Kosaki, G; Shimozuma, K; Tominaga, T; Yoshida, Y | 1 |
| Bojda-Diolez, F; Corbani, M; Dussaillant, M; Kerdelhué, B; Pasqualini, C; Rostène, W; Sarrieau, A | 1 |
| Kangas, L | 1 |
| Iino, Y; Ishikawa, H; Izuo, M; Ogawa, T; Takikawa, H; Yoshida, M | 1 |
| Monden, A; Morimoto, T; Yamamoto, H | 1 |
| Clark, ER; Robinson, SP; Whitaker, EM; Zoltowski, JA | 1 |
| Iino, Y; Ishikawa, H; Izuo, M; Takikawa, H | 1 |
| Haaparanta, M; Kangas, L; Paul, R; Roeda, D; Sipilä, H | 1 |
| Bakker, GH; De Jong, FH; Foekens, JA; Klijn, JG; Portengen, H; Setyono-Han, B | 1 |
| Kitamura, M; Kosaki, G; Tominaga, T; Yoshida, Y | 1 |
| Bhatnagar, AS; Matter, A; Schieweck, K | 1 |
| Alitalo, K; Sandberg, M; Vuorio, E; Vuorio, T; Wärri, A | 1 |
| Jordan, VC; Mauel, DA; Robinson, SP | 1 |
| Ip, C; Ip, MM; Sylvester, PW | 1 |
| Brodie, AM; Santen, RJ | 1 |
| Ronan, AM; Thompson, HJ | 1 |
| Kamioki, S | 1 |
| Hattori, Y; Imaizumi, A; Kosaka, A; Kuzuoka, M; Yamafuji, K; Yamashita, A | 1 |
| Hilf, R; Roghmann, MC; Skinner, KA | 1 |
| Boccardo, F; Cerruti, G; De Menech, R; Valenti, G; Zanardi, S | 1 |
| Jordan, VC; Robinson, SP | 1 |
| Akagi, M; Fujino, N; Kimura, M; Shigaki, N; Takano, S | 1 |
| Clark, ER; Mackay, D; Robinson, SP | 1 |
| Hendry, LB; Muldoon, TG | 1 |
| Alvarez, E; Calaf, G; Jordan, C; Ramírez, G; Rodríguez, R | 1 |
| Inui, K; Komaki, K; Monden, Y; Morimoto, T; Sonoo, H | 1 |
| Bollag, W; Teelmann, K | 1 |
| Andrushchak, LI; Khaetskaia, VI; Khaetskiĭ, IK; Nikitchenko, VV; Pinchuk, VG | 1 |
| Barbi, GP; Boccardo, F; Dandolo, G; De Menech, R; Guarneri, D; Moro, MG; Paganuzzi, M; Pino, G; Sanguineti, M; Zanardi, S | 1 |
| Brueggemann, GL; King, MM; Magarian, RA; Terao, J | 1 |
| Berger, M; Prekajac, J; von Angerer, E | 1 |
| Katzenellenbogen, BS; Mangel, WF; Wei, LL | 1 |
| Brueggemann, G; King, MM; Magarian, RA; Pento, JT | 1 |
| Bodwin, JS; Cho-Chung, YS; Hirayama, PH; Rego, JA | 1 |
| Hartmann, RW; Schönenberger, H; Wrobel, KH | 1 |
| Hartmann, RW | 1 |
| Imura, H; Kato, Y; Matsushita, N; Waseda, N | 1 |
| DiPaolo, JA; Evans, CH; Greiner, JW | 1 |
| DeHoog, JV; Welsch, CW | 1 |
| Bennett, DR; Black, LJ; Clemens, JA; Jones, CD | 1 |
| Ballou, RJ; Safa, AR; Tseng, MT | 1 |
| Aylsworth, CF; Meites, J; Sylvester, PW; Van Vugt, DA | 1 |
| Safa, AR; Tseng, MT | 1 |
| Daniel, CP; Gaskell, SJ; Nicholson, RI | 1 |
| Hatori, Y; Imaizumi, A; Kosaka, A; Mori, F; Wani, T; Yamashita, A | 1 |
| Irigoyen, ML; Nardi, J; Sarría, JA; Sosa, R | 1 |
| Furr, BJ; Nicholson, RI | 1 |
| Dix, CJ; Jordan, VC; Naylor, KE; Prestwich, G | 1 |
| Allen, KE; Jordan, VC | 1 |
| Aflallo, L; Feldman, B; Glick, SM; Levy, J; Liel, Y | 1 |
| Brown, CK; Goodrich-Smith, M; Johnson, D; Mackie, D; Welsch, CW | 1 |
| Matsushima, E; Ogawa, K; Shibata, J; Sugimoto, Y; Toko, T; Yamaya, H; Yoshida, M | 1 |
| Cai, Q; Wei, H | 1 |
| Bruns, C; Pollak, M; Stolz, B; Tolcsvai, L; Weckbecker, G | 1 |
| Kawamura, I; Lacey, E; Manda, T; Nishigaki, F; Shimomura, K; Tanaka, Y | 1 |
| Maucher, A; von Angerer, E | 1 |
| Gibson, DF; Johnson, DA; Jordan, VC; Lababidi, MK; Langan-Fahey, SM; Wolberg, WH | 1 |
| Warren, RC; Zimniski, SJ | 1 |
| Di Salle, E; Giudici, D; Zaccheo, T | 1 |
| Callens, M; De Coster, R; Goeminne, N; Janssens, B; Van Ginckel, R; Wouters, L | 1 |
| Kawabe, M; Miyata, E; Sano, M; Shirai, T; Takahashi, S; Takesada, Y | 1 |
| Blankenstein, MA; Ensing, GJ; Herscheid, JD; Klok, RP; Kruijer, PS; van den Koedijk, CD; Verzeijlbergen, JF; Voskuil, JH | 1 |
| Brackett, DJ; Hanas, JS; Hollingsworth, AB; Lerner, MR; Lightfoot, SA; McCay, PB; Wilkerson, KB | 1 |
| Giri, AK; Gupta, S; Mukhopadhyay, A; Ray, S | 1 |
| Cockcroft, N; Dahllund, J; Härkönen, P; Hemminki, K; Kangas, L; Koskinen, M; Laine, A; Peng, Z; Qu, Q; Väänänen, K; Zheng, H | 1 |
| Cho, E; Clarke, R; Halakivi-Clarke, L; Liao, DJ; Onojafe, I | 1 |
| Adámeková, E; Ahlers, I; Ahlersová, E; Bojková, B; Cermáková, M; Kubatka, P; M ciková-Kalická, K; Mníchová-Chamilová, M | 1 |
| Cho, MY; Jang, TJ; Kim, JR; Park, JH | 1 |
| Giri, AK; Mukhopadhyay, A; Ray, S | 1 |
| Ben-Hur, H; Kossoy, G; Zusman, I | 1 |
| Iino, Y | 1 |
| Dowty, HV; LaDow, K; Succop, P; Talaska, G; Warshawsky, D | 1 |
| Gear, RB; Heffelfinger, SC; LaDow, K; Lu, F; Pyle, AL; Schneider, J; Warshawsky, D; Yan, M | 1 |
| Bohlmann, R; Gieschen, H; Heinrich, N; Hoffmann, J; Hofmeister, H; Kroll, J; Künzer, H; Lichtner, RB; Nishino, Y; Parczyk, K; Sauer, G; Schneider, MR; Ulbrich, HF | 1 |
| Asano, H; Chambon, P; Conti, F; Frame, MC; Grant, SG; Hodivala-Dilke, K; Komiyama, NH; McLean, GW; Metzger, D; Reynolds, L; Serrels, B | 1 |
| Aoyagi, Y; Asao, T; Buzdar, AU; Hashimoto, A; Sato, K; Shibata, J; Terada, T; Wierzba, K; Yamamoto, Y; Yano, S; Yonekura, K | 1 |
| Perumal, SS; Sachdanandam, P; Shanthi, P | 2 |
| Yao, ZX; Zeng, XZ | 1 |
| Beckett, LA; Degregorio, MW; Gregg, JP; Marchisano-Karpman, C; Read, KC; Wurz, GT; Yu, Q | 1 |
| Balapure, AK; Mishra, R; Murthy, PS; Panda, G; Sharma, R; Srivastava, AK | 1 |
| Dai, ZJ; Kang, HF; Liu, XX; Wang, XJ; Xue, FJ; Xue, XH | 2 |
| DeGregorio, MW; Marchisano-Karpman, C; Wurz, GT | 1 |
| Carbajal, S; Clifford, JL; DiGiovanni, J; Kataoka, K; Kim, DJ | 1 |
| Hirtreiter, C; Ishibashi, K; Nishino, T; Nishino, Y | 1 |
| Chen, JJ; Kim, HJ; Kim, SY; Laxmi, YR; Liu, X; Okamoto, K; Okamoto, Y; Shibutani, S; Suzuki, N; Zhang, G | 1 |
| Petroff, BK; Ting, AY | 1 |
| Chen, JJ; Kim, HJ; Laxmi, YR; Liu, X; Okamoto, K; Okamoto, Y; Shibutani, S; Suzuki, N; Zhang, G | 1 |
| Bhadauria, S; Mishra, R; Murthy, PK; Murthy, PS | 1 |
| Gong, Z; He, S; Hogendoorn, PC; Krens, SG; Snaar-Jagalska, BE; Spaink, HP; Zhan, H | 1 |
| Ai, W; Huang, S; Li, J; Liu, C; Wang, TC; Yu, F; Yu, T; Zheng, H | 1 |
| Aleem, E; Baddour, N; Daba, A; El-Saadani, M; Mansour, A | 1 |
| Amarji, B; Bhatia, A; Katare, OP; Raza, K; Shukla, A; Singh, B | 1 |
| Flågeng, MH; Gjerde, J; Gudbrandsen, OA; Lien, EA; Madsen, A; Mellgren, G; Moi, LL; Røst, TH | 1 |
| Alimirah, F; Hawthorne, M; Kalra, A; Kopelovich, L; Mehta, RG; Mehta, RR; Peng, X; Roy, S | 1 |
| Kim, SH; Lee, MG; Suh, JH; Yang, SH | 1 |
| Amberg, N; Glitzner, E; Holcmann, M; Novoszel, P; Sibilia, M; Stulnig, G | 1 |
| Gayen, JR; Hussain, KM; Mishra, DP; Rama Raju, KS; Singh, SK; Singh, SP; Taneja, I; Tripathi, A; Wahajuddin, M | 1 |
| Bao, R; Bechill, J; Bindokas, VP; Faber, PW; Lingen, MW; Spiotto, MT; Zhong, R | 1 |
| Awounfack, CF; Bishayee, A; Cisilotto, J; Creczynski-Pasa, TB; Magne Nde, CB; Mefegue, FA; Melachio Tanekou, TT; Michel, T; Ndinteh, DT; Njamen, D; Sandjo, LP; Silihe, KK; Tueche, AB; Winter, E; Zingue, S | 1 |
| Dora, CP; Jena, SK; Pawar, H; Singh, C; Suresh, S; Varthya, M | 1 |
| Bouker, KB; Clarke, R; Cook, KL; Cruz, MI; de Assis, S; Hilakivi-Clarke, L; Hu, R; Jin, L; Nguyen, N; Wang, X; Wang, Y; Wärri, A; Wehrenberg, B; Xuan, J; Zhang, X; Zwart, A | 1 |
| Clarke, R; Cook, KL; Cruz, IM; Doerge, D; Helferich, W; Hilakivi-Clarke, L; Riskin, J; Rosim, M; Warri, A; Zhang, X | 1 |
| Ashrafi, M; Karimi, B; Shomali, T; Yektaseresht, A | 1 |
| Carney, E; Clarke, R; De Oliveira Andrade, F; FitzGerald, K; Hilakivi-Clarke, L; Hu, R; Yu, W; Zhang, X | 1 |
| Choupo, A; Fotsing, SI; Ngo Pambe, JC; Njamen, D; Pieme, CA; Silihe, KK; Yembeau, NL; Zingue, S | 1 |
| Bhattacharjee, K; Choudhury, Y; Laskar, YB; Mazumder, PB; Nath, M; Talukdar, AD | 1 |
6 review(s) available for 9,10-dimethyl-1,2-benzanthracene and tamoxifen
| Article | Year |
|---|---|
Aromatase in breast cancer and the role of aminoglutethimide and other aromatase inhibitors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult; Aged; Aminoglutethimide; Androgens; Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Estrogens; Female; Humans; Mammary Neoplasms, Experimental; Metabolic Clearance Rate; Middle Aged; Rats; Tamoxifen | 1986 |
[A study model of estrogens and antiestrogens analysis].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Binding Sites; Estrogen Antagonists; Estrogens; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Neoplasm Transplantation; Rats; Tamoxifen | 1987 |
Laboratory studies to develop general principles for the adjuvant treatment of breast cancer with antiestrogens: problems and potential for future clinical applications.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Disease Models, Animal; Dose-Response Relationship, Drug; Estrogen Antagonists; Female; Half-Life; Humans; Mammary Neoplasms, Experimental; Models, Biological; Piperidines; Pyrrolidines; Raloxifene Hydrochloride; Rats; Rats, Inbred Strains; Receptors, Estrogen; Tamoxifen; Thiophenes | 1983 |
Use of analogues of luteinizing hormone-releasing hormone for the treatment of cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Drug Therapy, Combination; Female; Gonadotropin-Releasing Hormone; Goserelin; Male; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Rats; Tamoxifen | 1982 |
Anti-oestrogen action in experimental breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chemical Phenomena; Chemistry; Dose-Response Relationship, Drug; Endometrium; Estrogen Antagonists; Estrogens; Female; Hypertrophy; Mammary Neoplasms, Experimental; Mitosis; Prolactin; Rats; Receptors, Estrogen; Tamoxifen; Uterus | 1980 |
Endocrine and cytostatic treatment of experimental mammary cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carmustine; Castration; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Ergolines; Female; Fluorouracil; Mammary Neoplasms, Experimental; Methotrexate; Methylnitrosourea; Mice; Nitrosourea Compounds; Prednisolone; Rats; Tamoxifen; Vincristine | 1980 |
2 trial(s) available for 9,10-dimethyl-1,2-benzanthracene and tamoxifen
| Article | Year |
|---|---|
Aromatase in breast cancer and the role of aminoglutethimide and other aromatase inhibitors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult; Aged; Aminoglutethimide; Androgens; Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Estrogens; Female; Humans; Mammary Neoplasms, Experimental; Metabolic Clearance Rate; Middle Aged; Rats; Tamoxifen | 1986 |
[Synergistic action of lentinan (LNT) with endocrine therapy of breast cancer in rats and humans].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenalectomy; Adult; Animals; Breast Neoplasms; Combined Modality Therapy; Drug Synergism; Female; Humans; Lentinan; Mammary Neoplasms, Experimental; Middle Aged; Ovariectomy; Polysaccharides; Random Allocation; Rats; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1987 |
127 other study(ies) available for 9,10-dimethyl-1,2-benzanthracene and tamoxifen
| Article | Year |
|---|---|
[Early effect of estradiol on ultrastructure of chromatin in the endometrium and hormone-dependent mammary tumors].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Chromatin; Dihydrotestosterone; Endometrium; Estradiol; Female; Heterochromatin; In Vitro Techniques; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Progesterone; Rats; Receptors, Estrogen; Sheep; Tamoxifen; Time Factors | 1978 |
Control of experimental breast cancer by antioestrogenic therapies [proceedings].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Female; Mammary Neoplasms, Experimental; Ovary; Rats; Tamoxifen | 1979 |
Tamoxifen as an anti-tumour agent: effect on oestrogen binding.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estradiol; Female; Mammary Neoplasms, Experimental; Rats; Receptors, Cell Surface; Stilbenes; Tamoxifen; Uterus; Vagina | 1976 |
Predominant role of prolactin in stimulating the growth of 7, 12-dimethylbenz(a)anthracene-induced rat mammary tumor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetonitriles; Animals; Benz(a)Anthracenes; Drug Administration Schedule; Ergolines; Estrogens; Female; Mammary Neoplasms, Experimental; Ovary; Perphenazine; Prolactin; Rats; Receptors, Cell Surface; Receptors, Estrogen; Tamoxifen | 1977 |
Early increases in ribonucleic acid polymerase activities of dimethylbenzanthracene-induced mammary tumour nuclei in response to oestradiol-17beta and tamoxifen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Nucleus; Cytoplasm; DNA-Directed RNA Polymerases; Estradiol; Mammary Neoplasms, Experimental; Rats; Receptors, Estrogen; Stilbenes; Tamoxifen; Time Factors | 1977 |
Effects of oestradiol-17beta and tamoxifen on nuclear oestradiol-17beta receptors in DMBA-induced rat mammary tumours.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Nucleus; Estradiol; Female; Mammary Neoplasms, Experimental; Rats; Receptors, Estrogen; Stilbenes; Tamoxifen; Temperature | 1977 |
The effect of ovariectomy, tamoxifen and the combination adriamycin and 5-FU on 7,12-dimethylbenz(a)anthracene induced mammary cancer of the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Castration; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Mammary Neoplasms, Experimental; Rats; Remission, Spontaneous; Stilbenes; Tamoxifen | 1977 |
Tamoxifen as an anti-tumour agent: role of oestradiol and prolactin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estradiol; Estrus; Female; Organ Size; Pregnancy; Prolactin; Rats; Stilbenes; Tamoxifen; Uterus | 1976 |
The effect of synthetic anti-oestrogens on the growth and biochemistry of rat mammary tumours.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Estradiol; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Prolactin; Rats; Stilbenes; Tamoxifen | 1975 |
Effect of tamoxifen (ICI 46,474) on initiation and growth of DMBA-induced rat mammary carcinomata.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Cell Division; Estradiol; Female; Mammary Neoplasms, Experimental; Prolactin; Rats; Stilbenes; Tamoxifen; Time Factors | 1976 |
Effects of oestradiol - 17beta and tamoxifen on total and accessible cytoplasmic oestradiol - 17beta receptors in DMBA-induced rat mammary tumours.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cytoplasm; Estradiol; Female; Mammary Neoplasms, Experimental; Rats; Stilbenes; Tamoxifen; Temperature; Time Factors | 1976 |
Antiestrogenic and antitumor properties of tamoxifen in laboratory animals.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Antineoplastic Agents; Binding, Competitive; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Rats; Receptors, Estrogen; Stilbenes; Tamoxifen | 1976 |
Down-regulation of tenascin expression by antiprogestins during terminal differentiation of rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Adhesion Molecules, Neuronal; Cell Differentiation; Extracellular Matrix Proteins; Female; Gonanes; Immunohistochemistry; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovariectomy; Progesterone; Rats; Tamoxifen; Tenascin; Uterus | 1992 |
[Experimental study of combination medical endocrine therapy on DMBA-induced mammary tumor, with special reference to the effect of drug-dose on various factors].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Female; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Organ Size; Rats; Tamoxifen | 1992 |
Role of tamoxifen in the induction of hormone-independent rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Tamoxifen | 1992 |
Antitumor effects of droloxifene, a new antiestrogen drug, against 7,12-dimethylbenz(a)anthracene-induced mammary tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Cytosol; Estradiol; Estrogen Antagonists; Female; Iodine Radioisotopes; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Promegestone; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1991 |
Effects of sequential and combined immuno-endocrine therapies using OK-432 (Picibanil) and tamoxifen on the growth of 7,12-dimethylbenz [alpha] anthracene-induced rat mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Mammary Neoplasms, Experimental; Picibanil; Rats; Rats, Inbred Strains; Tamoxifen | 1991 |
Effects of OK-432 (Picibanil) on estrogen receptor levels and tamoxifen treatment in 7,12-dimethylbenz[a]anthracene-induced rat mammary cancers.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biological Products; Female; Mammary Neoplasms, Experimental; Picibanil; Rats; Rats, Inbred Strains; Receptors, Estrogen; Tamoxifen | 1990 |
Modulatory influences of tamoxifen, tocopherol, retinyl acetate, aminoglutethimide, ergocryptine and selenium on DMBA-induced initiation of mammary carcinogenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminoglutethimide; Animals; Diterpenes; Drug Interactions; Ergolines; Female; Mammary Neoplasms, Experimental; Rats; Retinyl Esters; Selenium; Tamoxifen; Vitamin A; Vitamin E | 1990 |
Chemoendocrine therapy in DMBA-induced rat mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1990 |
Antiestrogenic and antitumor properties of the new triphenylethylene derivative toremifene in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Antineoplastic Agents; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Receptors, Estrogen; Tamoxifen; Toremifene; Uterus | 1990 |
Antitumor effects of combination toremifene and medroxyprogesterone acetate (MPA) in vitro and in vivo.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Estrogen Antagonists; Female; Humans; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Ovarian Neoplasms; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Toremifene; Tumor Cells, Cultured | 1990 |
Additive and synergistic antitumor effects with toremifene and interferons.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Breast Neoplasms; Drug Interactions; Drug Synergism; Estrogen Antagonists; Female; Humans; Interferon Type I; Interferon-gamma; Mammary Neoplasms, Animal; Rats; Tamoxifen; Time Factors; Toremifene; Tumor Cells, Cultured | 1990 |
Effect of CGS 16949A plus tamoxifen on induced mammary tumours in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Estrone; Fadrozole; Female; Follicle Stimulating Hormone; Imidazoles; Luteinizing Hormone; Mammary Neoplasms, Experimental; Nitriles; Prolactin; Rats; Rats, Inbred Strains; Tamoxifen | 1990 |
Estrogen-like effects of 7,12-dimethylbenz(a)anthracene on the female rat hypothalamo-pituitary axis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Binding Sites; Binding, Competitive; Brain; Cytosol; Estrogens; Female; Hypothalamo-Hypophyseal System; Kinetics; Luteinizing Hormone; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Estradiol; Reference Values; Spiperone; Tamoxifen | 1990 |
Biochemical and pharmacological effects of toremifene metabolites.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Cell Division; Mammary Neoplasms, Experimental; Mice; Rats; Receptors, Estrogen; Tamoxifen; Toremifene; Tumor Cells, Cultured | 1990 |
Effects of sequential and combined endocrine therapies on the growth of 7,12-dimethylbenz [alpha] anthracene-induced rat mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Ovariectomy; Rats; Rats, Inbred Strains; Tamoxifen | 1990 |
[Effects of chemo-endocrine therapy on DMBA-induced rat mammary carcinoma].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1989 |
The effect of pregnant mares serum gonadotrophin on the response of DMBA induced rat mammary tumours to tamoxifen or oestrogen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Diethylstilbestrol; Drug Interactions; Female; Gonadotropins, Equine; Mammary Neoplasms, Experimental; Ovariectomy; Rats; Rats, Inbred Strains; Tamoxifen | 1989 |
Sequential hormone therapy with medroxyprogesterone acetate for 7, 12-dimethylbenz [alpha] anthracene-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Drug Therapy, Combination; Estradiol; Female; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1989 |
Biodistribution and scintigraphy of 11C-toremifene in rats bearing DMBA-induced mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chemical Phenomena; Chemistry; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Rats; Tamoxifen; Tissue Distribution; Tomography, Emission-Computed; Toremifene | 1989 |
Endocrine and antitumor effects of combined treatment with an antiprogestin and antiestrogen or luteinizing hormone-releasing hormone agonist in female rats bearing mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Buserelin; Cytosol; Drug Implants; Estrenes; Female; Follicle Stimulating Hormone; Goserelin; Injections, Subcutaneous; Luteinizing Hormone; Mammary Neoplasms, Experimental; Mifepristone; Progestins; Rats; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1989 |
Effective sequential administration of tamoxifen and medroxyprogesterone acetate for 7,12-dimethylbenz[a-anthracene-induced rat mammary tumors in relation to hormone receptors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Drug Administration Schedule; Female; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Rats; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Time Factors | 1985 |
CGS 16949A, a new nonsteroidal aromatase inhibitor: effects on hormone-dependent and -independent tumors in vivo.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminoglutethimide; Animals; Aromatase Inhibitors; Body Weight; Cell Line; Drug Screening Assays, Antitumor; Fadrozole; Female; Imidazoles; Mammary Neoplasms, Experimental; Nitriles; Rats; Tamoxifen | 1988 |
Expression of the c-Ha-ras and neu oncogenes in DMBA-induced, anti-estrogen-treated rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Deoxyribonucleases, Type II Site-Specific; DNA, Neoplasm; Estrogen Antagonists; Gene Expression Regulation; Genes, ras; Mammary Neoplasms, Experimental; Oncogenes; Rats; Rats, Inbred Strains; RNA, Neoplasm; Tamoxifen; Toremifene | 1988 |
Antitumor actions of toremifene in the 7,12-dimethylbenzanthracene (DMBA)-induced rat mammary tumor model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estrogen Antagonists; Mammary Neoplasms, Experimental; Progesterone; Rats; Rats, Inbred Strains; Tamoxifen; Toremifene | 1988 |
Effects of high dietary fat on the growth and development of ovarian-independent carcinogen-induced mammary tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromocriptine; Dietary Fats; Estrogens; Female; Mammary Neoplasms, Experimental; Ovariectomy; Ovary; Prolactin; Rats; Tamoxifen | 1986 |
Effect of D,L-2-difluoromethylornithine and endocrine manipulation on the induction of mammary carcinogenesis by 1-methyl-1-nitrosourea.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dose-Response Relationship, Drug; Eflornithine; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovariectomy; Polyamines; Rats; Rats, Inbred Strains; Tamoxifen | 1986 |
[Ultrastructural study of rat mammary tumors and human breast cancer cells following treatment with tamoxifen].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult; Aged; Animals; Breast Neoplasms; Cell Nucleolus; Female; Humans; Mammary Neoplasms, Experimental; Microscopy, Electron; Middle Aged; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1986 |
Effects of estradiol and tamoxifen on creatine kinase in rodent mammary carcinomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenylate Kinase; Animals; Creatine Kinase; Estradiol; Female; Glucosephosphate Dehydrogenase; Isoenzymes; L-Lactate Dehydrogenase; Mammary Neoplasms, Experimental; Ovariectomy; Rats; Rats, Inbred Strains; Tamoxifen; Uterus | 1987 |
Priming action on progesterone receptor synthesis by estradiol and tamoxifen in the 7,12-dimethylbenz(a)anthracene-induced rat mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estradiol; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1987 |
Reversal of the antitumor effects of tamoxifen by progesterone in the 7,12-dimethylbenzanthracene-induced rat mammary carcinoma model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Drug Interactions; Estradiol; Estrenes; Estrogens; Estrone; Mammary Neoplasms, Experimental; Mifepristone; Organ Size; Progesterone; Rats; Tamoxifen | 1987 |
Reduction of estrogen and prolactin receptors in 7,12-dimethylbenz(a)anthracene-induced rat mammary tumor by high doses of estrogen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estradiol; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Receptors, Prolactin; Tamoxifen | 1987 |
Application of a mathematical model for two component receptor binding to two high affinity oestrogen binding sites in nuclei from DMBA rat mammary tumours.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Binding Sites; Cell Nucleus; Estradiol; Mammary Neoplasms, Experimental; Mathematics; Models, Theoretical; Rats; Receptors, Estrogen; Tamoxifen | 1988 |
Actions of an endogenous antitumorigenic agent on mammary tumor development and modeling analysis of its capacity for interacting with DNA.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzeneacetamides; DNA, Neoplasm; Female; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Orchiectomy; Piperidines; Piperidones; Rats; Tamoxifen | 1988 |
Changes in the hormone dependency of DMBA-induced rat mammary tumors with reference to the effect of tamoxifen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Rats; Rats, Inbred Strains; Receptors, Estradiol; Receptors, Progesterone; Tamoxifen | 1988 |
Therapeutic effect of the arotinoid Ro 15-0778 on chemically induced rat mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Retinoids; Tamoxifen | 1988 |
[Modeling of differentiation and physiological involution in the tissues of induced cancer of the mammary gland].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Cell Survival; Estrogens; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Papaverine; Rats; Tamoxifen; Vitamin A | 1988 |
Effects of tamoxifen, estradiol benzoate and medroxyprogesterone acetate on the growth of DMBA-induced rat mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Drug Synergism; Estradiol; Female; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Rats; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1985 |
Effects of nonsteroidal antiestrogens, analog II and tamoxifen, on a metastatic transplantable rat mammary tumor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mammary Neoplasms, Experimental; Neoplasm Metastasis; Neoplasm Transplantation; Rats; Rats, Inbred Strains; Tamoxifen | 1985 |
The inhibitory effect of 5-acetoxy-2-(4-acetoxyphenyl)-1-ethyl-3-methylindole (D 16726) on estrogen-dependent mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Female; Humans; Indoles; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Rats; Rats, Inbred Strains; Receptors, Estrogen; Tamoxifen | 1985 |
Biological activities of tamoxifen aziridine, an antiestrogen-based affinity label for the estrogen receptor, in vivo and in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Affinity Labels; Animals; Cell Division; Female; Humans; In Vitro Techniques; Mammary Neoplasms, Experimental; Organ Size; Plasminogen Activators; Rats; Rats, Inbred Strains; Receptors, Estrogen; Tamoxifen; Uterus | 1985 |
The interaction of dietary fat and antiestrogen treatment on DMBA-induced mammary tumors in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dietary Fats; Female; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Rats; Rats, Inbred Strains; Tamoxifen | 1985 |
Regression of hormone-dependent mammary tumors in Sprague-Dawley rats as a result of tamoxifen or pharmacologic doses of 17 beta-estradiol: cyclic adenosine 3',5'-monophosphate-mediated events.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Nucleus; Cyclic AMP; Estradiol; Female; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Phosphorylation; Protein Kinases; Rats; Tamoxifen | 1981 |
3,4-bis(3'-hydroxyphenyl)hexane--a new mammary tumor-inhibiting compound. Studies on the mechanism of action on the DMBA-induced, hormone-dependent mammary tumor of the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carbohydrate Metabolism; Castration; Female; Hexestrol; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Rats; Rats, Inbred Strains; Tamoxifen; Uterus | 1982 |
Tumor growth-stimulating and inhibiting effects of antiestrogens on the DMBA-induced mammary carcinoma of the ovariectomized, diethylstilbestrol-treated SD rat. A study on the mechanism of action of antiestrogens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Cell Division; Diethylstilbestrol; Estrogen Antagonists; Female; Hexestrol; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Tamoxifen | 1983 |
Effects of bromocriptine and tamoxifen on growth and hormone receptor levels of 7,12-dimethylbenz(a)anthracene-induced mammary tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromocriptine; Female; Mammary Neoplasms, Experimental; Prolactin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Estrogen; Receptors, Progesterone; Receptors, Prolactin; Tamoxifen | 1983 |
Carcinogen-induced phenotypic alterations in mammary epithelial cells accompanying the development of neoplastic transformation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Epithelium; Female; Mammary Glands, Animal; Phenotype; Rats; Rats, Inbred Strains; Tamoxifen; Tetradecanoylphorbol Acetate | 1983 |
Retinoid feeding, hormone inhibition, and/or immune stimulation and the genesis of carcinogen-induced rat mammary carcinomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Bromocriptine; Cell Division; Diterpenes; Female; Kinetics; Mammary Neoplasms, Experimental; Mycobacterium bovis; Nocardia; Rats; Retinyl Esters; Tamoxifen; Vitamin A | 1983 |
Effects of a new antiestrogen, keoxifene (LY156758), on growth of carcinogen-induced mammary tumors and on LH and prolactin levels.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Drug Evaluation, Preclinical; Estradiol; Estrogen Antagonists; Female; Luteinizing Hormone; Mammary Neoplasms, Experimental; Piperidines; Prolactin; Raloxifene Hydrochloride; Rats; Rats, Inbred Strains; Tamoxifen | 1983 |
Response of 7,12-dimethylbenz(a)anthracene-induced rat mammary tumor cells to tamoxifen, in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Microscopy, Electron; Molecular Weight; Proteins; Rats; Rats, Inbred Strains; Tamoxifen | 1983 |
Effects of alterations in early hormonal environment on development and hormone dependency of carcinogen-induced mammary tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromocriptine; Castration; Estradiol; Female; Haloperidol; Mammary Neoplasms, Experimental; Ovary; Rats; Rats, Inbred Strains; Tamoxifen | 1983 |
In vitro drug screening and individualized treatment planning for cancer patients.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Cells, Cultured; Dose-Response Relationship, Drug; Doxorubicin; Drug Evaluation, Preclinical; Female; Humans; Mammary Neoplasms, Experimental; Methotrexate; Neoplasms; Rats; Rats, Inbred Strains; Tamoxifen | 1983 |
The measurement of tamoxifen and metabolites in the rat and relationship to the response of DMBA-induced mammary tumours.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dose-Response Relationship, Drug; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Receptors, Estrogen; Tamoxifen | 1984 |
[Cumulative effects of lentinan and endocrine therapy on the growth of DMBA-induced mammary tumor in rats].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenalectomy; Animals; Benz(a)Anthracenes; Castration; Cell Survival; Combined Modality Therapy; Female; Histamine; Lentinan; Mammary Neoplasms, Experimental; Polysaccharides; Rats; Rats, Inbred Strains; Tamoxifen | 1984 |
[Tamoxifen as a suppressor of mammary carcinogenesis induced by 7,12-dimethyl-benzanthracene and methylnitrosourea, in female rats with induced hyperprolactinemia].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Female; Methylnitrosourea; Nitrosourea Compounds; Prolactin; Rats; Sulpiride; Tamoxifen | 1983 |
Evaluation of the antitumour activity of the non-steroidal antioestrogen monohydroxytamoxifen in the DMBA-induced rat mammary carcinoma model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Dose-Response Relationship, Drug; Estradiol; Female; Mammary Neoplasms, Experimental; Organ Size; Promegestone; Rats; Tamoxifen; Uterus | 1980 |
Peroxidase activity in mammary tumors - effect of tamoxifen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cytosol; Female; Mammary Neoplasms, Experimental; Peroxidases; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1981 |
2-bromo-alpha-ergocryptine (CB-154) and tamoxifen (ICI 46,474) induced suppression of the genesis of mammary carcinomas in female rats treated with 7,12-dimethylbenzanthracene (DMBA): a comparison.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromocriptine; Drug Synergism; Female; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Precancerous Conditions; Rats; Rats, Inbred Strains; Tamoxifen; Time Factors | 1982 |
Comparative antioestrogen action in experimental breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Tamoxifen; Uterus | 1981 |
Comparative pharmacodynamic analysis of TAT-59 and tamoxifen in rats bearing DMBA-induced mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Hormonal; Binding, Competitive; Estradiol; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Tamoxifen | 1995 |
In vivo formation of DNA-adducts in mouse skin DNA by tamoxifen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; DNA; DNA Adducts; DNA Damage; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred SENCAR; Skin; Tamoxifen | 1995 |
Somatostatin analogue octreotide enhances the antineoplastic effects of tamoxifen and ovariectomy on 7,12-dimethylbenz(alpha)anthracene-induced rat mammary carcinomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Combined Modality Therapy; Drug Administration Schedule; Drug Synergism; Female; Mammary Neoplasms, Experimental; Octreotide; Organ Size; Ovariectomy; Rats; Rats, Sprague-Dawley; Receptors, Somatostatin; Tamoxifen; Uterus | 1994 |
Binding sites of droloxifene in the cytosol of 7,12-dimethylbenz[a]anthracene-induced rat mammary tumor cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Binding Sites; Chromatography, High Pressure Liquid; Cytosol; Estradiol; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Tamoxifen; Tritium; Tumor Cells, Cultured | 1994 |
Antitumour activity of coumarin and 7-hydroxycoumarin against 7,12-dimethylbenz[a]anthracene-induced rat mammary carcinomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Coumarins; Drug Evaluation, Preclinical; Female; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Tamoxifen; Time Factors; Umbelliferones | 1994 |
The effects of intermittent progesterone upon tamoxifen inhibition of tumor growth in the 7,12-dimethylbenzanthracene rat mammary tumor model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mammary Neoplasms, Experimental; Progesterone; Rats; Rats, Sprague-Dawley; Tamoxifen; Uterus | 1993 |
Induction of tamoxifen-dependent rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Cell Division; Cocarcinogenesis; Female; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Rats; Rats, Sprague-Dawley; Tamoxifen | 1993 |
Inhibitory effect of combined treatment with the aromatase inhibitor exemestane and tamoxifen on DMBA-induced mammary tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Glands; Androstadienes; Animals; Antineoplastic Agents; Aromatase Inhibitors; Drug Synergism; Female; Mammary Neoplasms, Experimental; Organ Size; Ovary; Pituitary Gland; Rats; Rats, Sprague-Dawley; Tamoxifen; Uterus | 1993 |
Effects of combined and sequential treatment with tamoxifen and the aromatase inhibitor vorozole on 7,12-dimethylbenz(a) anthracene-induced mammary carcinoma in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Androstenedione; Animals; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Carcinogens; Disease Models, Animal; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Female; Luteinizing Hormone; Mammary Neoplasms, Experimental; Ovariectomy; Progesterone; Rats; Rats, Sprague-Dawley; Tamoxifen; Triazoles | 1996 |
Effects of tamoxifen, an antiestrogen, on rat prostate carcinogenesis by 3,2'-dimethyl-4-aminobiphenyl and testosterone do not support an estrogen role in testosterone promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Line, Transformed; Estrogen Antagonists; Male; Organ Size; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Rats; Seminal Vesicles; Tamoxifen; Testosterone; Tumor Cells, Cultured | 1997 |
Biodistribution of 123I-labeled 4-hydroxytamoxifen derivatives in rats with dimethylbenzanthracene-induced mammary carcinomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Binding Sites; Carcinogens; Estrogen Antagonists; Female; Iodine Radioisotopes; Mammary Neoplasms, Experimental; Radiopharmaceuticals; Rats; Rats, Wistar; Tamoxifen; Tissue Distribution | 1997 |
Prevention of DMBA-induced rat mammary carcinomas comparing leuprolide, oophorectomy, and tamoxifen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Hormonal; Estrogen Antagonists; Female; Leuprolide; Mammary Neoplasms, Experimental; Ovariectomy; Rats; Rats, Sprague-Dawley; Tamoxifen | 1998 |
Anticlastogenic effects of centchroman and its enantiomers in Swiss albino mice. I. Acute study and their comparison with tamoxifen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antimutagenic Agents; Antineoplastic Agents; Centchroman; Chromosome Aberrations; Cyclophosphamide; Estrogen Antagonists; Female; Mice; Mice, Inbred Strains; Mutagens; Sister Chromatid Exchange; Stereoisomerism; Tamoxifen | 1999 |
Selective estrogenic effects of a novel triphenylethylene compound, FC1271a, on bone, cholesterol level, and reproductive tissues in intact and ovariectomized rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bone and Bones; Breast Neoplasms; Cholesterol; Estrogen Antagonists; Female; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Organ Size; Osteoporosis; Ovariectomy; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Reference Values; Tamoxifen; Toremifene; Transplantation, Heterologous; Tumor Cells, Cultured; Uterus | 2000 |
Maternal exposure to tamoxifen during pregnancy increases carcinogen-induced mammary tumorigenesis among female rat offspring.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinogens; Female; Litter Size; Mammary Neoplasms, Experimental; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Tamoxifen; Time Factors; Weight Gain | 2000 |
Effects of tamoxifen and melatonin on mammary gland cancer induced by N-methyl-N-nitrosourea and by 7,12-dimethylbenz(a)anthracene, respectively, in female Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Estrogen Receptor Modulators; Female; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Tamoxifen | 2001 |
Chemically induced rat mammary tumor treated with tamoxifen showed decreased expression of cyclin D1, cyclin E, and p21(Cip1).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromodeoxyuridine; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Female; Gene Expression; Mammary Neoplasms, Animal; Rats; Rats, Sprague-Dawley; Tamoxifen; Treatment Outcome | 2001 |
Anticlastogenic effects of d- and l-centchroman in Swiss albino mice. 2. Subacute study in vivo and comparison with tamoxifen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antimutagenic Agents; Antineoplastic Agents; Bone Marrow Cells; Centchroman; Chromosome Aberrations; Cyclophosphamide; Female; Mice; Stereoisomerism; Tamoxifen | 2001 |
Soluble low-molecular-mass tumor-associated antigens promote the suppression of rat mammary tumors by tamoxifen and prevent its toxic effect.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Female; Mammary Neoplasms, Experimental; Molecular Weight; Rats; Rats, Wistar; Solubility; Survival Rate; Tamoxifen; Time Factors | 2002 |
Treatment of tamoxifen-refractory breast cancer--approach by animal models.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Cyclohexanes; Disease Models, Animal; Female; Mammary Neoplasms, Experimental; Mice; Mice, Nude; O-(Chloroacetylcarbamoyl)fumagillol; Picibanil; Prognosis; Rats; Receptors, Estrogen; Risk Assessment; Sesquiterpenes; Tamoxifen; Tegafur; Treatment Failure; Uracil | 2001 |
Reduction of a 7,12-dimethylbenz[a]anthracene DNA adduct in rat mammary tissue in vivo when pretreated with tamoxifen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Autoradiography; Biotransformation; Carcinogens; DNA; DNA Adducts; Female; Hydrolysis; Mammary Glands, Animal; Rats; Rats, Sprague-Dawley; Tamoxifen | 2002 |
TNP-470 inhibits 7,12-dimethylbenz[a]anthracene-induced mammary tumor formation when administered before the formation of carcinoma in situ but is not additive with tamoxifen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Angiogenesis Inhibitors; Animals; Antibiotics, Antineoplastic; Carcinogens; Carcinoma in Situ; Carcinoma, Intraductal, Noninfiltrating; Cyclohexanes; Disease Models, Animal; Drug Interactions; Female; Mammary Neoplasms, Experimental; Neovascularization, Pathologic; O-(Chloroacetylcarbamoyl)fumagillol; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Tamoxifen | 2003 |
Characterization of new estrogen receptor destabilizing compounds: effects on estrogen-sensitive and tamoxifen-resistant breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Disease Models, Animal; Disease Progression; Drug Resistance, Neoplasm; Estradiol; Estrogen Receptor Modulators; Estrogens; Female; Humans; Injections, Subcutaneous; Methylnitrosourea; Mice; Neoplasms, Hormone-Dependent; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Tamoxifen; Transplantation, Heterologous | 2004 |
Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Blotting, Western; DNA Primers; Flow Cytometry; Fluorescent Antibody Technique; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gene Deletion; Genotype; Hydroxytestosterones; Immunohistochemistry; Integrases; Keratin-14; Keratinocytes; Keratins; Mice; Mice, Transgenic; Neoplasm Metastasis; Protein-Tyrosine Kinases; Receptors, Estrogen; Skin Neoplasms; Tamoxifen | 2004 |
TAS-108, a novel oral steroidal antiestrogenic agent, is a pure antagonist on estrogen receptor alpha and a partial agonist on estrogen receptor beta with low uterotrophic effect.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Carcinogens; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogen Receptor Modulators; Female; Fulvestrant; Genes, Reporter; Humans; Luciferases; Mice; Mice, Nude; Models, Chemical; Neoplasm Transplantation; Ovary; Protein Binding; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Tamoxifen; Time Factors; Transcriptional Activation; Treatment Outcome; Uterus | 2005 |
Augmented efficacy of tamoxifen in rat breast tumorigenesis when gavaged along with riboflavin, niacin, and CoQ10: effects on lipid peroxidation and antioxidants in mitochondria.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Antioxidants; Body Weight; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Coenzymes; Drug Combinations; Female; Lipid Peroxidation; Mitochondria; Niacin; Rats; Rats, Sprague-Dawley; Riboflavin; Tamoxifen; Ubiquinone | 2005 |
[Effect of tamoxifen plus octreotide on DMBA-induced mammary tumors in rats].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Hormonal; Drug Synergism; Female; Mammary Neoplasms, Experimental; Octreotide; Random Allocation; Rats; Rats, Wistar; Tamoxifen | 2005 |
Combined efficacy of tamoxifen and coenzyme Q10 on the status of lipid peroxidation and antioxidants in DMBA induced breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Antineoplastic Agents, Hormonal; Antioxidants; Cell Proliferation; Coenzymes; Cytoprotection; Drug Combinations; Female; Lipid Peroxidation; Malondialdehyde; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Tamoxifen; Ubiquinone | 2005 |
Ospemifene inhibits the growth of dimethylbenzanthracene-induced mammary tumors in Sencar mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinoma; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred SENCAR; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Tamoxifen | 2005 |
Substituted phenanthrenes with basic amino side chains: a new series of anti-breast cancer agents.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acids; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Inhibitory Concentration 50; Mammary Neoplasms, Experimental; Models, Chemical; Phenanthrenes; Rats; Tamoxifen; Time Factors | 2006 |
[Chemopreventive effect of tamoxifen combined with celecoxib on DMBA-induced breast cancer in rats].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Celecoxib; Drug Administration Routes; Drug Synergism; Female; Mammary Neoplasms, Experimental; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides; Tamoxifen | 2006 |
[Chemopreventive effect of celecoxib against DMBA-induced breast cancer and its mechanism].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Celecoxib; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Down-Regulation; Female; Immunohistochemistry; Mammary Neoplasms, Experimental; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides; Tamoxifen; Treatment Outcome; Vascular Endothelial Growth Factor A | 2006 |
Ineffectiveness of American ginseng in the prevention of dimethylbenzanthracene-induced mammary tumors in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred SENCAR; Panax; Phytotherapy; Plant Preparations; Plant Roots; Selective Estrogen Receptor Modulators; Tamoxifen; Time Factors | 2006 |
Stage-specific disruption of Stat3 demonstrates a direct requirement during both the initiation and promotion stages of mouse skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Western; Carcinogens; Cell Transformation, Neoplastic; Immunohistochemistry; Mice; Mice, Transgenic; Polymerase Chain Reaction; Signal Transduction; Skin Neoplasms; STAT3 Transcription Factor; Tamoxifen; Tetradecanoylphorbol Acetate | 2008 |
Potentiation of the antitumor effect of tamoxifen by combination with the antiprogestin onapristone.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Female; Gonanes; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Tamoxifen | 2009 |
Anti-breast cancer potential of SS1020, a novel antiestrogen lacking estrogenic and genotoxic actions.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; DNA Adducts; Endometrial Neoplasms; Estrogen Antagonists; Estrogen Receptor Modulators; Female; Humans; Mammary Neoplasms, Experimental; Mice; Rats; Tamoxifen; Uterus | 2010 |
Tamoxifen decreases ovarian follicular loss from experimental toxicant DMBA and chemotherapy agents cyclophosphamide and doxorubicin in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Cells, Cultured; Cyclophosphamide; Doxorubicin; Female; Fertility; Oocytes; Ovarian Follicle; Ovary; Protective Agents; Rats; Rats, Sprague-Dawley; Tamoxifen | 2010 |
Anti-breast cancer potential of SS5020, a novel benzopyran antiestrogen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cinnamates; DNA Adducts; Estrogen Receptor Modulators; Female; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplastic Cells, Circulating; Rats; Rats, Sprague-Dawley; Tamoxifen; Umbelliferones | 2011 |
Glycine soya diet synergistically enhances the suppressive effect of tamoxifen and inhibits tamoxifen-promoted hepatocarcinogenesis in 7,12-dimethylbenz[α]anthracene-induced rat mammary tumor model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Apoptosis; Cell Proliferation; Diet; Drug Synergism; Female; Glutathione S-Transferase pi; Glycine max; Liver Neoplasms; Mammary Neoplasms, Experimental; Organ Size; Rats; Rats, Sprague-Dawley; Tamoxifen | 2011 |
A ΔRaf1-ER-inducible oncogenic zebrafish liver cell model identifies hepatocellular carcinoma signatures.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Hepatocellular; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms, Experimental; MAP Kinase Signaling System; Neoplasm Transplantation; Proto-Oncogene Proteins c-raf; Tamoxifen; Transplantation, Heterologous; Tumor Cells, Cultured; Zebrafish | 2011 |
Deficiency of the Kruppel-like factor KLF4 correlates with increased cell proliferation and enhanced skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cell Adhesion; Cell Differentiation; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Female; Gene Expression Regulation, Neoplastic; Humans; Keratinocytes; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Mice; Mice, Transgenic; RNA Interference; RNA, Small Interfering; Skin Neoplasms; Tamoxifen; Tetradecanoylphorbol Acetate | 2012 |
Schizophyllan inhibits the development of mammary and hepatic carcinomas induced by 7,12 dimethylbenz(α)anthracene and decreases cell proliferation: comparison with tamoxifen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspase 3; Cell Proliferation; Female; Immunohistochemistry; Liver Neoplasms, Experimental; Mammary Neoplasms, Experimental; Mice; Proliferating Cell Nuclear Antigen; Receptors, Estrogen; Schizophyllum; Sizofiran; Survival Analysis; Tamoxifen | 2012 |
Tamoxifen-loaded novel liposomal formulations: evaluation of anticancer activity on DMBA-TPA induced mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Cutaneous; Animals; Antineoplastic Agents, Hormonal; Cocarcinogenesis; Drug Compounding; Drug Delivery Systems; Female; Liposomes; Mice; Skin Neoplasms; Tamoxifen; Tetradecanoylphorbol Acetate; Treatment Outcome | 2012 |
Steroid receptor coactivators, HER-2 and HER-3 expression is stimulated by tamoxifen treatment in DMBA-induced breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Hormonal; Body Weight; Female; Gene Expression Regulation, Neoplastic; Humans; Mammary Neoplasms, Experimental; Nuclear Receptor Coactivators; Proto-Oncogene Protein c-ets-2; Rats; Rats, Sprague-Dawley; Receptor, ErbB-2; Receptor, ErbB-3; RNA, Messenger; Tamoxifen; Tumor Burden | 2012 |
PPARγ antagonist GW9662 induces functional estrogen receptor in mouse mammary organ culture: potential translational significance.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Anilides; Animals; Anticarcinogenic Agents; Drug Synergism; Estradiol; Estrogen Receptor alpha; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Oxazoles; PPAR gamma; Precancerous Conditions; Receptors, Progesterone; Tamoxifen; Tissue Culture Techniques; Transcriptional Activation; Tyrosine | 2013 |
Pharmacokinetic drug interactions between ondansetron and tamoxifen in female Sprague-Dawley rats with DMBA-induced mammary tumor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Antiemetics; Area Under Curve; Carcinogens; Drug Interactions; Female; Infusions, Intravenous; Mammary Neoplasms, Experimental; Ondansetron; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators; Tamoxifen | 2013 |
Mouse models of nonmelanoma skin cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Culture Techniques; DNA; Epidermis; Humans; Keratinocytes; Mice; Skin Neoplasms; Staining and Labeling; Tamoxifen; Tetradecanoylphorbol Acetate | 2015 |
Simultaneous determination of centchroman and tamoxifen along with their metabolites in rat plasma using LC-MS/MS.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Centchroman; Chromatography, Liquid; Female; Mammary Neoplasms, Experimental; Metabolomics; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Tamoxifen; Tandem Mass Spectrometry; Tissue Distribution | 2015 |
Notch1 Activation or Loss Promotes HPV-Induced Oral Tumorigenesis.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Carcinogens; Carcinoma, Verrucous; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cocarcinogenesis; Disease Progression; DNA Transposable Elements; Female; Humans; Mice; Mice, Transgenic; Mouth Neoplasms; Mutagenesis, Insertional; Neoplasm Invasiveness; Oncogenes; Papilloma; Papillomaviridae; Receptor, Notch1; Skin Neoplasms; Specific Pathogen-Free Organisms; Tamoxifen; Tetradecanoylphorbol Acetate; Tumor Virus Infections; Uterine Cervical Neoplasms | 2015 |
Crateva adansonii DC, an African ethnomedicinal plant, exerts cytotoxicity in vitro and prevents experimental mammary tumorigenesis in vivo.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Africa; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Capparaceae; Chromatography, Liquid; DNA Damage; Dose-Response Relationship, Drug; Ethnobotany; Female; Human Umbilical Vein Endothelial Cells; Humans; Inhibitory Concentration 50; Lethal Dose 50; Mammary Neoplasms, Experimental; MCF-7 Cells; Medicine, African Traditional; Mice; Molecular Structure; NIH 3T3 Cells; Oxidative Stress; Phytotherapy; Plant Extracts; Plants, Medicinal; Rats, Wistar; Spectrometry, Mass, Electrospray Ionization; Tamoxifen; Time Factors; Tumor Burden | 2016 |
Development of Novel Polymer-Lipid Hybrid Nanoparticles of Tamoxifen: In Vitro and In Vivo Evaluation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Drug Carriers; Drug Screening Assays, Antitumor; Female; Mammary Neoplasms, Experimental; Nanoparticles; Rats; Rats, Sprague-Dawley; Tamoxifen | 2016 |
Effects of In Utero Exposure to Ethinyl Estradiol on Tamoxifen Resistance and Breast Cancer Recurrence in a Preclinical Model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenovirus E1A Proteins; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; DNA Methylation; Drug Resistance, Neoplasm; Ethinyl Estradiol; Female; Galectin 3; Gene Expression; Gene Silencing; Histocompatibility Antigens Class I; Humans; Hydralazine; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Mammary Neoplasms, Experimental; Neoplasm Recurrence, Local; Pregnancy; Prenatal Exposure Delayed Effects; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ets; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Tamoxifen; Trans-Activators; Valproic Acid | 2017 |
Lifetime Genistein Intake Increases the Response of Mammary Tumors to Tamoxifen in Rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Hormonal; Autophagy; Cytokines; Diet; Endoplasmic Reticulum Chaperone BiP; Estrogen Receptor Modulators; Female; Gene Expression Regulation, Neoplastic; Genistein; Isoflavones; Mammary Neoplasms, Experimental; Phytoestrogens; Rats; Rats, Sprague-Dawley; Recurrence; Soy Foods; Tamoxifen; Unfolded Protein Response | 2017 |
Therapeutic effect of simvastatin on DMBA-induced breast cancer in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antioxidants; Aryldialkylphosphatase; Dinoprostone; Dose-Response Relationship, Drug; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Malondialdehyde; Mammary Neoplasms, Experimental; Mice; Mucin-1; Oxidative Stress; Simvastatin; Tamoxifen | 2019 |
Effects of Jaeumkanghwa-tang on tamoxifen responsiveness in preclinical ER+ breast cancer model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cytokines; Drug Resistance, Neoplasm; Endometrium; Estrogen Antagonists; Female; Forkhead Transcription Factors; Humans; Mammary Neoplasms, Experimental; Medicine, East Asian Traditional; Neoplasm Recurrence, Local; Plant Extracts; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Tamoxifen; Transforming Growth Factor beta1; Tumor Microenvironment | 2019 |
Breast cancer cell growth arrest and chemopreventive effects of Passiflora edulis Sims (Passifloraceae) ethanolic leaves extract on a rat model of mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antioxidants; Carcinoma; Ethanol; Letrozole; Passiflora; Passifloraceae; Plant Extracts; Rats; Rats, Wistar; Tamoxifen | 2023 |
Protective Effects of Pelargonidin against DMBA-Induced Mammary Tumorigenesis in BALB/c Mice through Reduced Oxidative Stress and Lipid Anomalies.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Female; Lipids; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Oxidative Stress; Tamoxifen | 2023 |