9,10-dimethyl-1,2-benzanthracene has been researched along with medroxyprogesterone acetate in 42 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (28.57) | 18.7374 |
| 1990's | 13 (30.95) | 18.2507 |
| 2000's | 5 (11.90) | 29.6817 |
| 2010's | 10 (23.81) | 24.3611 |
| 2020's | 2 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Horiuchi, R; Iino, Y; Ishikita, T; Maemura, M; Morishita, Y; Ohwada, S; Sugamata, N; Yokoe, T; Yoshida, M | 1 |
| Kosaka, A; Yamashita, A | 1 |
| Grönroos, M; Kangas, L | 1 |
| Iino, Y; Ishikawa, H; Izuo, M; Ogawa, T; Takikawa, H; Yoshida, M | 1 |
| Ashino-Fuse, H; Hiragun, A; Iwaguchi, T; Oikawa, T; Tominaga, T; Yoshida, Y | 1 |
| Iino, Y; Ishikawa, H; Izuo, M; Takikawa, H | 2 |
| Dupuis, M; Gimotty, P; Russo, IH; Russo, J | 1 |
| Dauvois, S; Labrie, F; Spinola, PG | 1 |
| Kitamura, M; Kosaki, G; Tominaga, T; Yoshida, Y | 1 |
| Barbi, GP; Boccardo, F; Dandolo, G; De Menech, R; Guarneri, D; Moro, MG; Paganuzzi, M; Pino, G; Sanguineti, M; Zanardi, S | 1 |
| Itoh, I; Kitamura, M; Saito, T; Tominaga, T | 1 |
| Falautano, P; Filippeschi, S; Malfiore, C; Noseda, S; Serraglia, N; Spreafico, F | 1 |
| Arai, T; Endo, K; Hirai, T; Iino, Y; Ishikawa, H; Izuo, M; Kawai, T; Ogawa, T; Takikawa, H; Yamazaki, K | 1 |
| Casazza, AM; di Marco, A; di Salle, E; Pollini, C; Zaccheo, T | 1 |
| Arai, T; Endo, K; Hoshino, K; Iino, Y; Ishida, T; Ishikawa, H; Ogawa, T; Takahashi, T; Yamazaki, K; Yokoe, T | 1 |
| Geng, CS; Labrie, F; Lévesque, C; Li, S; Yan, X | 1 |
| Bélanger, A; Côté, J; Labrie, F; Lepage, M; Li, S; Mérand, Y | 1 |
| Bélanger, A; Labrie, F; Lepage, M; Li, S; Mérand, Y | 1 |
| Funahashi, H; Imai, T; Kikumori, T; Morita, T; Narita, T; Oiwa, M; Takagi, H; Tanaka, Y; Tobinaga, J; Tsukamura, K; Wada, M; Yamada, F | 1 |
| Aldaz, CM; Johnston, DA; LaBate, M; Liao, QY | 1 |
| Aldaz, CM; Liao, QY; Paladugu, A; Rehm, S; Wang, H | 1 |
| Labrie, C; Labrie, F; Luo, S; Stojanovic, M | 1 |
| Hara, Y; Kudo, H; Kuwa, K; Mitamura, T; Okayasu, I; Sakamoto, S; Sassa, S; Shinoda, H; Suzuki, S | 1 |
| Buck, TB; Bunce, OR; Harris, SR; Thorgeirsson, UP; Yoshiji, H | 1 |
| Hibino, S; Kohno, T; Murata, N; Oikawa, T; Shimamura, M; Sugino, E; Tsuboi, H; Uchida, M; Yamaji, T | 1 |
| Besch-Williford, C; Day, JK; Hufford, MG; Lubahn, DB; MacDonald, RS; McMann, TR | 1 |
| Chen, Y; Rittling, SR | 1 |
| Benakanakere, I; Besch-Williford, C; Brandt, S; Ellersieck, MR; Hyder, SM; Molinolo, A; Schnell, J | 1 |
| Benakanakere, I; Besch-Williford, C; Ellersieck, MR; Hyder, SM | 1 |
| Branstetter, D; Dougall, WC; Erwert, R; Gonzalez-Suarez, E; Jacob, AP; Jones, J; Miller, R; Pinkas, J; Roudier-Meyer, MP | 1 |
| Benakanakere, I; Besch-Williford, C; Ellersieck, MR; Hyder, SM; López Pérez, FR; Mafuvadze, B | 1 |
| Besch-Williford, CL; Cook, M; Hyder, SM; Mafuvadze, B; Xu, Z | 1 |
| Blanco, MA; Bronson, RT; Chakrabarti, R; Chekmareva, M; Guo, F; Haffty, BG; Hua, Y; Kang, Y; Lu, X; Shen, M; Smith, HA; Wan, L; Wei, Y; Wu, H; Xing, Y; Yuan, M; Yuan, S | 1 |
| Chen, C; Ge, GZ; He, BL; Jiao, JL; Lv, LB; Wang, CY; Xia, HJ; Zhang, HL; Zhang, YX | 1 |
| Besch-Williford, C; Cook, MT; Ellersieck, MR; Goyette, S; Hyder, SM; Mafuvadze, B | 1 |
| Choi, MR; Christov, K; Ivancic, D; Khan, SA; Lee, O | 1 |
| Abba, MC; Aldaz, CM; Gaddis, S; Kil, H; Lee, J; Lu, Y; Shen, J; Simper, MS; Takata, Y; Zhong, Y | 1 |
| Allen, AM; Alorro, M; Chand, AL; Clyne, CD; Connelly, AA; Coulson, R; Deb, S; Ernst, M; George, AJ; Hannan, NJ; Harrison, CA; Kumar, B; Lazarus, KA; Liew, SH; Morrow, RJ; O'Toole, SA; Parslow, AC; Poh, A; Putoczki, T; Vargas, AC; Walton, KL; Yeap, EFW; Yee, NS | 1 |
| Chen, M; Jiang, W; Liao, X; Mao, A; Ou, C; Qin, Q; Tan, Q; Wei, C; Yang, C; Yang, W; Ye, X | 1 |
| Agnes, JP; Báfica, A; Bishop, AJR; Bruxel, MA; Casagrande, T; Cassali, GD; das Neves, RN; Delgobo, M; Falchetti, M; Garcia, APV; Gelain, DP; Gonçalves, RM; Mendes, DAGB; Moreira, JCF; Rafacho, A; Somensi, N; Vieira, TC; Zanotto-Filho, A | 1 |
| Bloy, N; Buqué, A; Galluzzi, L; Humeau, J; Kroemer, G; Perez-Lanzón, M; Petroni, G; Sato, A; Yamazaki, T | 1 |
42 other study(ies) available for 9,10-dimethyl-1,2-benzanthracene and medroxyprogesterone acetate
| Article | Year |
|---|---|
1 alpha-hydroxyvitamin D3, hypercalcemia, and growth suppression of 7,12-dimethylbenz[a]anthracene-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Female; Fluorouracil; Hydroxycholecalciferols; Hypercalcemia; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Rats; Rats, Sprague-Dawley; Weight Loss | 1992 |
[Experimental study of combination medical endocrine therapy on DMBA-induced mammary tumor, with special reference to the effect of drug-dose on various factors].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Female; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Organ Size; Rats; Tamoxifen | 1992 |
Antitumor effects of combination toremifene and medroxyprogesterone acetate (MPA) in vitro and in vivo.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Estrogen Antagonists; Female; Humans; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Ovarian Neoplasms; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Toremifene; Tumor Cells, Cultured | 1990 |
Effects of sequential and combined endocrine therapies on the growth of 7,12-dimethylbenz [alpha] anthracene-induced rat mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Ovariectomy; Rats; Rats, Inbred Strains; Tamoxifen | 1990 |
Angiogenic activity of rat mammary carcinomas induced by 7,12-dimethylbenz[a]anthracene and its inhibition by medroxyprogesterone acetate: possible involvement of antiangiogenic action of medroxyprogesterone acetate in its tumor growth inhibition.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cells, Cultured; Drug Interactions; Female; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Neovascularization, Pathologic; Rats; Rats, Inbred Strains | 1988 |
Sequential hormone therapy with medroxyprogesterone acetate for 7, 12-dimethylbenz [alpha] anthracene-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Drug Therapy, Combination; Estradiol; Female; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1989 |
Effect of medroxyprogesterone acetate on the response of the rat mammary gland to carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Drug Administration Schedule; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Rats; Rats, Inbred Strains; Weight Gain | 1989 |
Additive inhibitory effects of bromocryptine (CB-154) and medroxyprogesterone acetate (MPA) on dimethylbenz[a]anthracene (DMBA)-induced mammary tumors in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Bromocriptine; Drug Synergism; Female; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone | 1989 |
Effective sequential administration of tamoxifen and medroxyprogesterone acetate for 7,12-dimethylbenz[a-anthracene-induced rat mammary tumors in relation to hormone receptors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Drug Administration Schedule; Female; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Rats; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Time Factors | 1985 |
[Combined therapies with medroxyprogesterone acetate (MPA) in DMBA-induced rat mammary cancer].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Estrogens; Female; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Rats; Rats, Inbred Strains; Tegafur | 1986 |
Effects of tamoxifen, estradiol benzoate and medroxyprogesterone acetate on the growth of DMBA-induced rat mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Drug Synergism; Estradiol; Female; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Rats; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1985 |
Effects of hexestrol, medroxyprogesterone acetate and chlormadinone acetate on 7, 12-dimethylbenz [a] anthracene-induced rat mammary cancer in relation to estrogen receptor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Chlormadinone Acetate; Delayed-Action Preparations; Female; Hexestrol; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Rats; Rats, Inbred Strains; Receptors, Estrogen | 1981 |
Effect of medroxyprogesterone acetate on DMBA-induced rat mammary carcinoma and on immunological reactivity.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Female; Immunity; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Mice; Neoplasms, Hormone-Dependent; Rats | 1982 |
[Effect of medroxyprogesterone acetate (MAP) and vitamin C on DMBA induced rat mammary cancer in relation to estrogen receptor(ER)].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Ascorbic Acid; Female; Male; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Nandrolone; Rats; Rats, Inbred Strains; Receptors, Estrogen | 1983 |
Combined and sequential treatment using FCE 21336, a new prolactin-lowering drug, and medroxyprogesterone acetate (MPA) in DMBA-induced tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Castration; Female; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Prolactin; Rats; Rats, Inbred Strains | 1984 |
[Changes of hormone receptor status in various treatment for human breast cancer and DMBA tumor of the rat].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Middle Aged; Rats; Receptors, Estrogen; Receptors, Progesterone | 1984 |
Inhibitory effects of medroxyprogesterone acetate (MPA) and the pure antiestrogen EM-219 on estrone (E1)-stimulated growth of dimethylbenz(a)anthracene (DMBA)-induced mammary carcinoma in the rat.
Topics: 17-Hydroxysteroid Dehydrogenases; 9,10-Dimethyl-1,2-benzanthracene; Adrenal Glands; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Drug Synergism; Estradiol; Estrenes; Estrogen Antagonists; Estrone; Female; Follicle Stimulating Hormone; Luteinizing Hormone; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Neoplasms, Hormone-Dependent; Organ Size; Ovariectomy; Rats; Rats, Sprague-Dawley; Uterus | 1995 |
Controlled release low dose medroxyprogesterone acetate (MPA) inhibits the development of mammary tumors induced by dimethyl-benz(a) anthracene in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chemistry, Pharmaceutical; Delayed-Action Preparations; Dose-Response Relationship, Drug; Female; Injections, Subcutaneous; Lactic Acid; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rats, Sprague-Dawley | 1993 |
Growth inhibition of 7,12-dimethylbenz(a)anthracene-induced rat mammary tumors by controlled-release low-dose medroxyprogesterone acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Delayed-Action Preparations; Female; Follicle Stimulating Hormone; Injections, Subcutaneous; Luteinizing Hormone; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Microspheres; Rats; Rats, Sprague-Dawley | 1992 |
Suppressive effect of iodine on DMBA-induced breast tumor growth in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Female; Growth Inhibitors; Iodine; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Rats; Rats, Sprague-Dawley; Thyroid Gland | 1996 |
Medroxyprogesterone acetate accelerates the development and increases the incidence of mouse mammary tumors induced by dimethylbenzanthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Base Sequence; Carcinogens; DNA Primers; Drug Synergism; Exons; Female; Genes, ras; Humans; Incidence; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Polymerase Chain Reaction | 1996 |
Allelotypic and cytogenetic characterization of chemically induced mouse mammary tumors: high frequency of chromosome 4 loss of heterozygosity at advanced stages of progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Carcinogens; Chromosomes; Disease Progression; Female; Gene Deletion; Heterozygote; Karyotyping; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Neoplasm Staging; Neoplasm Transplantation | 1996 |
Inhibitory effect of the novel anti-estrogen EM-800 and medroxyprogesterone acetate on estrone-stimulated growth of dimethylbenz[a]anthracene-induced mammary carcinoma in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Glands; Animals; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Benzopyrans; Carcinogens; Cell Division; Drug Screening Assays, Antitumor; Estrogen Antagonists; Estrone; Female; Luteinizing Hormone; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Organ Size; Propionates; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, Progesterone; Uterus; Vagina | 1997 |
Additive effects of medroxyprogesterone acetate and 5-fluorouracil derivative on 7,12-dimethylbenz[a]anthracene-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Density; Estradiol; Female; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Organ Size; Polymerase Chain Reaction; Progesterone; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tegafur; Thymidine Kinase; Thymidylate Synthase; Transcription, Genetic | 1998 |
The effects of sustained elevated levels of circulating tissue inhibitor of metalloproteinases-1 on the development of breast cancer in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Enzyme-Linked Immunosorbent Assay; Female; Gelatinases; Humans; Mammary Neoplasms, Experimental; Matrix Metalloproteinase 2; Medroxyprogesterone Acetate; Metalloendopeptidases; Mice; Mice, Transgenic; Tissue Inhibitor of Metalloproteinase-1 | 1999 |
Inhibition by 9alpha-fluoromedoroxyprogesterone acetate (FMPA) against mammary carcinoma induced by dimethylbenz[a]anthracene in rats and angiogenesis in the rabbit cornea - comparison with medroxyprogesterone acetate (MPA).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cornea; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Neovascularization, Pathologic; Progesterone; Rabbits; Rats; Rats, Sprague-Dawley; Time Factors | 2000 |
Dietary genistein increased DMBA-induced mammary adenocarcinoma in wild-type, but not ER alpha KO, mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Caseins; Diet; Estradiol; Estrogen Receptor alpha; Female; Genistein; Insulin-Like Growth Factor I; Male; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mice; Mice, Inbred C57BL; Mice, Knockout; Organ Size; Ovary; Receptors, Estrogen; Skin Neoplasms; Uterus; Weight Gain | 2001 |
Novel murine mammary epithelial cell lines that form osteolytic bone metastases: effect of strain background on tumor homing.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Polyomavirus Transforming; Antineoplastic Agents, Hormonal; Bone Neoplasms; Carcinogens; Cell Transformation, Neoplastic; Epithelial Cells; Female; Genes, ras; Heart Ventricles; Humans; Keratins; Liver Neoplasms, Experimental; Male; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Neoplastic Cells, Circulating; Osteolysis; Osteopontin; Retroviridae; Sialoglycoproteins; Transfection; Tumor Cells, Cultured | 2003 |
Natural and synthetic progestins accelerate 7,12-dimethylbenz[a]anthracene-initiated mammary tumors and increase angiogenesis in Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Implants; Immunohistochemistry; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mifepristone; Neovascularization, Pathologic; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, Progesterone; Time Factors; Vascular Endothelial Growth Factors | 2006 |
Regression of progestin-accelerated 7,12-dimethylbenz[a]anthracene-induced mammary tumors in Sprague-Dawley rats by p53 reactivation and induction of massive apoptosis: a pilot study.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Apoptosis; Aza Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carcinogens; Drug Resistance, Neoplasm; Female; Mammary Neoplasms, Animal; Medroxyprogesterone Acetate; Mutation; Neovascularization, Pathologic; Osteonectin; Pilot Projects; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Tumor Suppressor Protein p53; Vascular Endothelial Growth Factor A | 2009 |
RANK ligand mediates progestin-induced mammary epithelial proliferation and carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Epithelial Cells; Female; Humans; Lung Neoplasms; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Medroxyprogesterone Acetate; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Invasiveness; Precancerous Conditions; Progesterone; Progestins; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B | 2010 |
Apigenin prevents development of medroxyprogesterone acetate-accelerated 7,12-dimethylbenz(a)anthracene-induced mammary tumors in Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apigenin; Dose-Response Relationship, Drug; Female; Immunohistochemistry; Mammary Neoplasms, Animal; Medroxyprogesterone Acetate; Neovascularization, Pathologic; Placebos; Rats; Rats, Sprague-Dawley; Receptors, Progesterone; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2011 |
Effects of dietary apigenin on tumor latency, incidence and multiplicity in a medroxyprogesterone acetate-accelerated 7,12-dimethylbenz(a)anthracene-induced breast cancer model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apigenin; Breast Neoplasms; Dietary Supplements; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hormone Replacement Therapy; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Postmenopause; Rats; Rats, Sprague-Dawley | 2013 |
MTDH-SND1 interaction is crucial for expansion and activity of tumor-initiating cells in diverse oncogene- and carcinogen-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Cell Adhesion Molecules; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Cell Transformation, Viral; Endonucleases; Female; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; HEK293 Cells; Humans; Mammary Glands, Animal; Mammary Tumor Virus, Mouse; Medroxyprogesterone Acetate; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Neoplasm Invasiveness; Neoplastic Stem Cells; Nuclear Proteins; Phenotype; Protein Binding; RNA Interference; RNA-Binding Proteins; Time Factors; Transfection; Tumor Cells, Cultured | 2014 |
PTEN/PIK3CA genes are frequently mutated in spontaneous and medroxyprogesterone acetate-accelerated 7,12-dimethylbenz(a)anthracene-induced mammary tumours of tree shrews.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Ductal, Breast; Carcinoma, Papillary; Disease Models, Animal; Estrogens; Female; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mutation; Papilloma, Intraductal; Phosphatidylinositol 3-Kinase; Progesterone; PTEN Phosphohydrolase; Random Allocation; Receptors, Estrogen; Receptors, Progesterone; Tupaiidae | 2014 |
Luteolin suppresses development of medroxyprogesterone acetate-accelerated 7,12-dimethylbenz(a)anthracene-induced mammary tumors in Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Estrogen Replacement Therapy; Female; Immunohistochemistry; Luteolin; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A | 2016 |
Progesterone receptor antagonism inhibits progestogen-related carcinogenesis and suppresses tumor cell proliferation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Angiogenesis Inhibitors; Animals; Antigens, CD34; Antineoplastic Agents, Hormonal; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Female; Hormone Antagonists; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Methylnitrosourea; Mice; Mifepristone; Neovascularization, Pathologic; Norpregnadienes; Progesterone; Progestins; Rats; Receptors, Estrogen; Receptors, Progesterone; Time Factors | 2016 |
DMBA induced mouse mammary tumors display high incidence of activating Pik3caH1047 and loss of function Pten mutations.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Class I Phosphatidylinositol 3-Kinases; DNA Mutational Analysis; Exome Sequencing; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mice, Inbred C57BL; Mice, Inbred DBA; Mutation; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; RANK Ligand; Sequence Analysis, RNA; Time Factors; Transcriptome | 2016 |
The angiotensin receptor blocker, Losartan, inhibits mammary tumor development and progression to invasive carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Angiotensin II Type 1 Receptor Blockers; Animals; Biopsy; Breast Neoplasms; Carcinogenesis; Carcinoma, Ductal, Breast; Carcinoma, Intraductal, Noninfiltrating; Cell Proliferation; Disease Progression; Female; Humans; Immunohistochemistry; Interleukin-6; Losartan; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mice; Neoplasm Invasiveness; Phosphorylation; Real-Time Polymerase Chain Reaction; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Signal Transduction; STAT3 Transcription Factor; Tumor Burden; Tumor Necrosis Factor-alpha; Up-Regulation | 2017 |
A Novel Animal Model of Induced Breast Precancerous Lesion in Tree Shrew.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Drug Synergism; Estrogen Receptor alpha; Female; Keratin-5; Keratin-6; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Precancerous Conditions; Receptor, ErbB-2; Receptors, Progesterone; Tupaiidae | 2019 |
COX-2 promotes mammary adipose tissue inflammation, local estrogen biosynthesis, and carcinogenesis in high-sugar/fat diet treated mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aromatase; Breast Neoplasms; Cell Line, Tumor; Chemokine CCL2; Cyclooxygenase 2; Diet, High-Fat; Dinoprostone; Disease Models, Animal; Etoricoxib; Female; Gene Expression Regulation, Neoplastic; Humans; Interleukin-6; MCF-7 Cells; Medroxyprogesterone Acetate; Mice; Sugars; Up-Regulation | 2021 |
MPA/DMBA-driven mammary carcinomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Carcinoma; Female; Humans; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mice; Mice, Inbred C57BL | 2021 |