9,10-dimethyl-1,2-benzanthracene has been researched along with benzo(a)pyrene in 227 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 98 (43.17) | 18.7374 |
| 1990's | 91 (40.09) | 18.2507 |
| 2000's | 31 (13.66) | 29.6817 |
| 2010's | 6 (2.64) | 24.3611 |
| 2020's | 1 (0.44) | 2.80 |
| Authors | Studies |
|---|---|
| Daniels, MJ; Dean, JH; Selgrade, MK | 1 |
| Bhattacharyya, KK; Jefcoate, CR; Otto, S | 1 |
| Conney, AH; Georgiadis, CA; Huang, MT; Laskin, JD; Wang, ZY | 1 |
| Halliday, GM; Muller, HK; Odling, KA | 1 |
| Bryla, P; Weyand, EH | 1 |
| Antony, M; Mehrotra, NK; Shukla, Y | 1 |
| Aoyama, T; Christou, M; Gelboin, HV; Gonzalez, FJ; Jefcoate, CR; Mitchell, MJ | 1 |
| Azuine, MA; Bhide, SV | 1 |
| Ferraro, T; Finnegan-Olive, T; Ho, CT; Huang, MT; Laskin, JD; Lou, YR; Mitchell, JM; Newmark, H; Wang, ZY; Yang, CS | 1 |
| Otsuka, M; Yang, HC | 1 |
| Hankinson, O | 1 |
| Andrews, FJ; Halliday, GM; Muller, HK; Narkowicz, CK | 1 |
| Abraham, SK | 1 |
| Fukuda, I; Morita, T; Nagaki, T; Okumura, K | 1 |
| Baker, R; He, SL | 1 |
| DiGiovanni, J | 1 |
| Bauchinger, M; Kulka, U; Paul, D; Salassidis, K; Schmid, E | 1 |
| Chouroulinkov, I; Lasne, C; Nguyen-Ba, G; Oueslatti, R | 1 |
| Alworth, WL; Sandoval, A; Slaga, TJ; Viaje, A; Warren, BS | 1 |
| Andrews, J; Halliday, GM; Muller, HK | 1 |
| Kawabata, TT; Ladics, GS; White, KL | 1 |
| Paumgartten, FJ; Röscheisen, C; Speit, G; Zamith, H | 1 |
| Butterworth, BE; DiGiovanni, J; Gill, RD; Nettikumara, AN | 1 |
| Castegnaro, M; Chambon, P; Chambon, R; Fouillet, B; Weill, N | 1 |
| Cavalieri, EL; Devanesan, PD; Higginbotham, S; RamaKrishna, NV; Rogan, EG; Salmasi, S; Todorovic, R | 1 |
| Cantu, AR; Pavone, A; Reiners, JJ | 1 |
| Frölich, A; Würgler, FE | 1 |
| Belitsky, GA; Budunova, IV; Mittelman, LA | 1 |
| Baer-Dubowska, W; DiGiovanni, J; Gill, RD; Morris, RJ | 1 |
| Alworth, WL; DiGiovanni, J; Hopkins, NE; Lu, JY; Nettikumara, AN; Slaga, TJ; Viaje, A | 1 |
| Georgellis, A; Parvinen, M; Rydström, J; Toppari, J; Veromaa, T | 1 |
| Elias, R; Nagabhushan, M; Ng, YK; Polverini, PJ; Solt, DB | 1 |
| Penn, A | 1 |
| Majeska, JB; Matheson, DW | 1 |
| Hallberg, E; Rydström, J | 1 |
| Meng, CL; Shyu, KW | 1 |
| Jefcoate, CR; Pottenger, LH | 1 |
| Gould, MN; Grau, DR; Moore, CJ; Seidman, LA | 1 |
| Fitzgerald, DJ; Klann, RC; Piccoli, C; Slaga, TJ; Yamasaki, H | 1 |
| Halliday, GM; Muller, HK; Ruby, JC | 1 |
| Ioannides, C; Phillipson, CE | 1 |
| Bickers, DR; Das, M; Mukhtar, H | 1 |
| Colby, AB; DiGiovanni, J; Gill, RD; Nettikumara, AN; Reiners, JJ | 1 |
| Athar, M; Khan, WA; Mukhtar, H | 1 |
| Austin, SJ; Beeman, DK; Lasley, JA; Mass, MJ; Schorschinsky, NS | 1 |
| Georgellis, A; Parvinen, M; Rydström, J | 1 |
| Burleson, GR; Daniels, MJ; Dean, JH; Lauer, LD; Selgrade, MJ | 1 |
| Ernst, MK; Hillesund, T; Poiley, JA; Raineri, R; Tennant, RW | 1 |
| Cabral, JR; Galendo, D; Hollstein, M; Martel, N; Tomatis, L; Yamasaki, H | 1 |
| Carluccio, MA; Gemperlein, I; Glatt, HR; Oesch, F; Turchi, G | 1 |
| Ball, JK; Dexter, D; Haliotis, T; Roder, JC | 1 |
| Abe, S | 1 |
| Christou, M; Dibartolomeis, MJ; Jefcoate, CR | 1 |
| Randerath, K; Reddy, MV | 1 |
| Hakaim, AG; Jacoby, WT; O'Connell, JF; Weiss, HS | 1 |
| Asakawa, M; Ito, N; Nakahara, H; Nakajima, T; Ohta, S; Sato, A; Shirai, T; Yonekura, I | 1 |
| Daniel, FB; Dixit, R; Schut, HA; Stoner, GD | 1 |
| DiGiovanni, J; Fisher, EP; Sawyer, TW | 1 |
| Anderson, TM; Cameron, JW; Hatch, GG; Kouri, RE; Lubet, RA; Nims, RW; Putman, DL; Schechtman, LM; Spalding, JW; Tennant, RW | 1 |
| Gould, MN; Moore, CJ; Tricomi, WA | 1 |
| Jacoby, WT; Weiss, HS | 1 |
| Barrowman, JA; Rahimtula, A; Rahman, A | 1 |
| Eldridge, SR; Gould, MN; Moore, CJ; Tricomi, WA | 1 |
| Marino, DJ | 1 |
| Baird, WM; DiGiovanni, J; Fisher, EP; Smolarek, TA | 1 |
| Baird, WM; Gould, MN; Mauthe, RJ; Moore, CJ; Pruess-Schwartz, D | 1 |
| Chang, K; DiGiovanni, J; Harvey, RG; Sawyer, TW | 1 |
| Baird, WM; Harvey, RG; Lee, H; Morgan, SL; Moynihan, CG; Smolarek, TA | 1 |
| Elmets, CA; Klemme, JC; Mukhtar, H | 1 |
| Baird, WM; Kelley, J; Morgan, SL; Smolarek, TA | 1 |
| Ammigan, N; Amonkar, AJ; Bhide, SV; D'Souza, AV; Maru, GB; Nagabhushan, M; Nair, UJ; Santhanam, U | 1 |
| Bickers, DR; Bik, DP; Das, M; Khan, WA; Mukhtar, H; Wang, ZY | 1 |
| Colby, AB; Reiners, JJ | 1 |
| Barrowman, JA; Laher, JM | 1 |
| Reiners, JJ | 1 |
| Herlick, S; Reiners, JJ | 1 |
| Edelman, AS; Sanchez, P; Thorbecke, GJ; Xue, B | 1 |
| Babish, JG; Johnson, BE; Mumma, RO; Rashid, KA | 1 |
| Heilbronn, R; Schlehofer, JR; zur Hausen, H | 1 |
| Bull, R; Laurie, D; Revis, NW; Schiller, CA | 1 |
| Dixit, A; Garg, LC; Rao, AR; Sutrave, P | 1 |
| Best, JB; Morita, M | 1 |
| Epstein, N; Knight, R; Morgan, K; Schor, NA | 1 |
| Benditt, EP; Bond, JA; Juchau, MR; Majesky, MW; Yang, HY | 1 |
| Cowell, JK | 1 |
| Kuszynski, C; Langenbach, R; Nesnow, S; Somogyi, A | 1 |
| Benditt, EP; Bond, JA; Gown, AM; Juchau, MR; Yang, HL | 1 |
| Langenbach, R; Malick, L; Nesnow, S | 1 |
| Boutwell, RK; DiGiovanni, J; Slaga, TJ | 1 |
| Marnett, LJ | 1 |
| Fazio, M; Tong, C; Williams, GM | 1 |
| Guenthner, TM; Lesca, P; Oesch, F | 1 |
| Isselbacher, KJ; Quaroni, A | 1 |
| Benfield, JR; Cohen, AH; Fu, PC; Hammond, WG; Jensen, T; Pak, HY; Paladugu, RR; Shors, EC; Teplitz, RL | 1 |
| Cooper, CS; Grover, PL; Hewer, A; Pal, K; Sims, P | 1 |
| Doerjer, G; Kleihues, P; Patzschke, K | 1 |
| Boutwell, RK; DiGiovanni, J; Rymer, J; Slaga, TJ | 1 |
| Boutwell, RK; Conrad, EA; Verma, AK | 1 |
| Kochhar, TS | 1 |
| Gould, MN | 1 |
| Cathers, LE; Gould, MN; Moore, CJ | 1 |
| Ashurst, SW; Diamond, L; DiGiovanni, J; Sina, JF; Singer, JM | 1 |
| Telang, S; Tong, C; Williams, GM | 1 |
| Grover, PL; Mironov, NM; Sims, P | 1 |
| Bengtsson, M; Mankowitz, L; Montelius, J; Rydström, J | 1 |
| Albert, RE; Burns, FJ | 1 |
| Arfellini, G; Capucci, A; Grilli, MP; Prodi, G; Rocchi, P | 1 |
| Bachhuber, AJ; Gould, MN; Moore, CJ | 1 |
| Bhide, SV; D'Souza, AV; Rao, KV | 1 |
| Bresnick, E | 1 |
| Gershon, H; Lichtig, C; Nahas, F | 1 |
| Mahlum, DD | 1 |
| Katz, M; Raj, AS | 1 |
| Abe, S; Nemoto, N; Sasaki, M | 1 |
| San, RH; Stich, HF; Whitehead, FW | 1 |
| Bigger, CA; Blake, DM; Dipple, A; Raymond, LG; Sawicki, JT | 1 |
| Bynum, G; Dean, RG; Hadley, E; Jacobson-Kram, D | 1 |
| Lesca, P | 1 |
| Agrawal, HP; Randerath, E; Randerath, K; Reddy, MV | 1 |
| D'argy, R; Hellman, B; Ullberg, S | 1 |
| Papadopoulos, D; Rydström, J; Seidegard, J | 1 |
| Baird, WM; Diamond, L; Salmon, CP | 1 |
| Nesnow, S; Reiners, JJ; Slaga, TJ | 1 |
| Gelman, RA; Sanders, CL; Skinner, C | 1 |
| Nesnow, S; Siegfried, JM | 1 |
| Christou, M; Jefcoate, CR; Turner, CR; Wilson, NM; Wrighton, SA | 1 |
| Hall, SD; Lee, AM; Murison, GL | 1 |
| Allen-Hoffmann, BL; Rheinwald, JG | 1 |
| Cerniglia, CE | 1 |
| Gasiorowski, K; Szyba, K; Urban, J | 1 |
| Fonouni-Fard, M; LaDow, K; Livingston, GK; Warshawsky, D | 1 |
| Fort, FL; Fujikawa, K; Sakamoto, Y; Samejima, K | 1 |
| Dandie, GW; Muller, HK; Ragg, SJ; Woods, GM | 1 |
| Kiefer, F; Kirsch-Volders, M; Tafazoli, M; Van Hummelen, P | 1 |
| Born, JL; Burchiel, SW; Krieger, JA; Maples, KR; Yuan, JW | 1 |
| Anderson, WH; Kiss, Z | 1 |
| Alvarado, ME; Calaf, G; Cox, T; Estrada, S; Russo, J; Tahin, Q | 1 |
| Montague, W; Raza, H | 1 |
| Jiang, H; Kato, R; Yamamoto, S | 1 |
| Baird, WM; Brozich, SL; Coffing, SL; Harvey, RG; Lau, HH; Lee, H; Schmerold, I | 1 |
| Colapietro, AM; Goodell, AL; Smart, RC | 1 |
| Anderson, WH; Crilly, KS; Kiss, Z | 1 |
| Conney, AH; Ferraro, T; Georgiadis, C; Ho, CT; Huang, MT; Laskin, JD; Lou, YR; Ma, W; Stauber, K; Wang, ZY | 1 |
| He, ZM; LaVoie, EJ; Meegalla, RL; Weyand, EH | 1 |
| Bauer, B; DiRado, M; Goodrow, T; Klein-Szanto, AJ; Ruggeri, B; Zhang, SY | 1 |
| Fischer, SM; Maldve, R; Pavone, A; Reiners, JJ | 1 |
| Bauchinger, M; Doehmer, J; Glatt, HR; Kulka, U | 1 |
| Cavalieri, EL; Higginbotham, S; Johansson, SL; RamaKrishna, NV; Rogan, EG | 1 |
| Hartmann, A; Speit, G | 1 |
| Bruijntjes-Rozier, GC; Evertz, SJ; Rompelberg, CJ; van den Heuvel, PD; Verhagen, H | 1 |
| Anderson, LM; Carter, J; Kovatch, RM; Pittinger, S; Riggs, CW; Ruskie, S | 1 |
| Larsson, BS; Roberto, A; Tjälve, H | 1 |
| Jiang, H; Kato, R; Ozawa, S; Shimada, M; Yamamoto, S; Yamazoe, Y | 1 |
| Biozzi, G; Bouthillier, Y; Covelli, V; Doria, G; Mouton, D; Neveu, T; Pioli, C; Saran, A | 1 |
| Ashwood-Smith, M; Baer-Dubowska, W; Cai, Y; DiGiovanni, J | 1 |
| Goodrow, T; Klein-Szanto, AJ; Liu, SC; Morris, R; Zhang, SY | 1 |
| Bradlow, HL; Katdare, M; Osborne, MP; Telang, NT | 1 |
| Möller, L; Zeisig, M | 1 |
| Dandie, GW; Egan, PJ; Muller, HK; Ragg, SJ; Woods, GM | 1 |
| Gilliard, G; Megosh, LC; O'Brien, TG; Soler, AP | 1 |
| Barton, SL; Burchiel, SW; Ethier, SP; Tannheimer, SL | 1 |
| Burchiel, SW; Davila, DR; Mounho, BJ | 1 |
| Drela, N; Izdebska-Szymona, K; Kopeć-Szlezak, J; Kozłowska, E; Pańczyk, S | 1 |
| Bostic, S; Cai, Y; DiGiovanni, J; Dubowski, A; Ivie, W; Johnston, D; Kleiner, H | 1 |
| Arif, JM; Gupta, RC; Smith, WA | 1 |
| Ariese, F; Cavalieri, E; Devanesan, P; Jankowiak, R; Rogan, E; Small, GJ; Todorovic, R | 1 |
| Cunningham, GD; Dabbs, JE; Hamilton, CM; Mirsalis, JC; Snyder, RD; Vernetti, LA | 1 |
| Glatt, HR; Hayashi, M; Matsuoka, A; Ozaki, M; Sakamoto, H; Sofuni, T; Takeshita, K | 1 |
| Petras, ML; Vrzoc, M | 1 |
| Aston, JP; Baan, RA; Booth, ED; Moorthy, B; Randerath, K; Sriram, P; van den Berg, PT; Watson, WP | 1 |
| Ho, SM; Hu, YF; Lau, KM; Russo, J | 1 |
| Furalyov, VA; Kravchenko, IV; Pylev, LN; Vasylieva, LA | 1 |
| Hayashi, M; Matsuoka, A; Matsuura, K; Sakamoto, H; Sofuni, T | 2 |
| Shukla, Y; Singh, A | 1 |
| Catterall, F; Clifford, MN; Copeland, E; Ioannides, C | 1 |
| Carreira, F; Estabrook, RW; Fisher, CW; Kranendonk, M; Laires, A; Rueff, J; Theisen, P; Vermeulen, NP | 1 |
| Gogate, SU; Mann, KK; Matulka, RA; Near, RI; Sherr, DH; Trombino, AF | 1 |
| Furihata, C; Katsumura, Y; Kobayashi, H; Mori, M; Sugiyama, C | 1 |
| Ciolino, HP; Yeh, GC | 1 |
| Han, HM; Jung, KK; Kang, SY; Kim, SH; Kim, TG; Lee, YK; Oh, HY; Rheu, HM | 1 |
| Baird, WM; Luch, A; Melendez-Colon, VJ; Seidel, A | 1 |
| Burchiel, SW; Davila, DR; Lane, JL; Lauer, FT | 1 |
| Cano, JP; Sabatier, R; Vian, L; Yusuf, AT | 1 |
| Borman, SM; Christian, PJ; Hoyer, PB; Sipes, IG | 1 |
| DiGiovanni, J; Johnson, WH; Kleiner, HE; Miller, L; Vulimiri, SV; Whitman, CP | 1 |
| Allpass, PR; McCully, KS; Reid, MC; Rinehimer, LA; Sunderman, FW; Taubman, SB | 1 |
| Iype, PT; Kelley, S; Ray-Chaudhuri, R | 1 |
| Chen, XG; Han, R; Li, LN; Li, Y; Yan, CH | 1 |
| Arora, A; Shukla, Y; Singh, A | 1 |
| Ciolino, HP; Daschner, PJ; Lopaczynska, J; MacDonald, CJ; Yeh, GC | 1 |
| Ball, JK | 1 |
| Shamberger, RJ | 1 |
| Adachi, K; Fukushima, A; Haresaku, M; Hayashi, M; Masuda, M; Nakamura, T; Nishikawa, T | 1 |
| Banejee, S; Dasgupta, T; Rao, AR; Yadav, PK | 1 |
| Cavin, C; Constable, A; Holzhaeuser, D; Huber, WW; Scharf, G; Schilter, B | 1 |
| Cano, JP; Guyomard, C; Vian, L; Yusuf, A | 1 |
| Chao, VA; Pritts, EA; Savouret, JF; Taylor, RN; Zhao, D | 1 |
| Soedigdo, P; Soedigdo, S; Tanudjojo, N | 1 |
| Lesca, P; Perrot, N; Peryt, B | 1 |
| Yang, J; Yin, M | 1 |
| DiGiovanni, J; Kleiner, HE; Reed, MJ | 1 |
| MALTONI, C; PRODI, G | 1 |
| Czuprynski, CJ; Galván, N; Jaskula-Sztul, R; Jefcoate, CR; MacWilliams, PS | 1 |
| Fulco, AJ; Kelly, SL; Lamb, DC; Lei, L; Waterman, MR | 1 |
| Gupta, KP; Singh, J | 1 |
| Dai, Q; Harvey, RG; Penning, TM; Ran, C | 1 |
| Dasgupta, T; Rao, AR; Yadava, PK | 1 |
| Banerjee, S; Dasgupta, T; Rao, AR; Yadava, PK | 1 |
| Baer-Dubowska, W; Brauze, D; Cichocki, M; Szaefer, H | 1 |
| Donovan, PJ; Nardone, R; Smith, GT | 1 |
| Czuprynski, CJ; Galván, N; Jefcoate, CR; MacWilliams, PS; Moorthy, B; Teske, DE; Zhou, G | 1 |
| Czuprynski, CJ; Galván, N; Jefcoate, CR; Page, TJ | 1 |
| Hioki, K; Hirose, M; Ishii, Y; Kanki, K; Kodama, Y; Kuroiwa, Y; Kurokawa, Y; Nishikawa, A; Nomura, T; Umemura, T | 1 |
| Nagase, H; Saito, J; Sakai, Y | 1 |
| Li, YL; Sanyal, MK | 1 |
| Baer-Dubowska, W; Krajka-Kuźniak, V; Szaefer, H | 1 |
| Clipson, L; Elmergreen, TL; Halberg, RB; Irving, AA; Jefcoate, CR; Ko, AY; Larsen, MC | 1 |
| Brandt, I; Brunström, B; Jönsson, ME | 1 |
| Avlasevich, S; Bemis, JC; Bryce, SM; Dertinger, SD; Franklin, D; Hyrien, O; Macgregor, JT; Palis, J; Phonethepswath, S; Raja, S; Torous, DK; Weller, P | 1 |
| Kale, RK; Singh, B | 1 |
| Camus, AC; Dong, W; Thornton, C; Wang, L; Willett, KL | 1 |
| Chipinda, I; Ruwona, TB; Siegel, PD; Templeton, SP | 1 |
| Orozco, LY; Ortiz, IC; Peláez, CA; Zuleta, M | 1 |
| Chen, Z; Dong, L; Dong, Y; Fang, F; Fu, M; Guo, X; Li, J; Liu, C; Liu, X; Ma, G; Ma, X; Shao, S; Xiao, J; Xue, L; Yang, X; Yu, L; Zhan, Q; Zhang, L; Zhang, W; Zhang, Y; Zhao, Q | 1 |
| Altinoz, MA; Alturfan, AA; Ateş, PS; Eğimezer, G; Elmaci, I; Emekli-Alturfan, E; Ünal, I; Üstündağ, FD; Üstündağ, ÜV | 1 |
9 review(s) available for 9,10-dimethyl-1,2-benzanthracene and benzo(a)pyrene
| Article | Year |
|---|---|
Modification of multistage skin carcinogenesis in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Cocarcinogenesis; Disease Models, Animal; Mice; Precancerous Conditions; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1991 |
International Commission for Protection Against Environmental Mutagens and Carcinogens. ICPEMC Working Paper 7/1/1. Mutational events in the etiology of arteriosclerotic plaques.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arsenic; Arteriosclerosis; Benzo(a)pyrene; DNA Damage; Herpesviridae; Humans; Methylcholanthrene; Mice; Muscle, Smooth, Vascular; Mutation; Transformation, Genetic | 1990 |
Planarians as a model system for in vitro teratogenesis studies.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Behavior, Animal; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Cadmium; Caffeine; Chlordan; Colchicine; Dactinomycin; Demecolcine; Drug Evaluation, Preclinical; Ethanol; Lead; Mercury; Models, Biological; Planarians; Puromycin; Reproduction; Teratogens; Thalidomide; Turbellaria | 1982 |
Polycyclic aromatic hydrocarbon oxidation during prostaglandin biosynthesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amines; Animals; Arachidonic Acid; Arachidonic Acids; Benzo(a)pyrene; Benzofurans; Benzopyrenes; Carcinogens; Dihydroxydihydrobenzopyrenes; Luminol; Nitrofurans; Oxidation-Reduction; Oxyphenbutazone; Phenylbutazone; Polycyclic Compounds; Prostaglandin-Endoperoxide Synthases; Prostaglandins | 1981 |
The price of progress or Pandora's purse.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Asbestos; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Carcinogens; Cocarcinogenesis; DNA; DNA Repair; Kinetics; Liver; Methylation; Polycyclic Compounds | 1983 |
Laboratory decontamination and destruction of carcinogens in laboratory wastes: some polycyclic aromatic hydrocarbons.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Biodegradation, Environmental; Carcinogens; Chemical Phenomena; Chemistry; Chemistry, Physical; Decontamination; Hydrogen-Ion Concentration; Laboratories; Methylcholanthrene; Oxidation-Reduction; Polycyclic Compounds; Potassium Permanganate; Safety; Solutions; Sulfuric Acids; Waste Products; World Health Organization | 1983 |
Microbial metabolism of polycyclic aromatic hydrocarbons.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthracenes; Bacteria; Benz(a)Anthracenes; Benzo(a)pyrene; Biodegradation, Environmental; Biotransformation; Carcinogens, Environmental; Eukaryota; Fungi; Humans; Mammals; Methylcholanthrene; Mice; Naphthalenes; Phenanthrenes; Polycyclic Compounds; Pyrenes; Structure-Activity Relationship | 1984 |
Estradiol metabolism: an endocrine biomarker for modulation of human mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Anticarcinogenic Agents; Benzo(a)pyrene; Biomarkers; Breast; Breast Neoplasms; Carcinogens; Cell Line; Culture Techniques; Dimethyl Sulfoxide; Estradiol; Estrogen Antagonists; Female; Humans; Indoles; Neoplasms, Hormone-Dependent | 1997 |
Cafestol and kahweol, two coffee specific diterpenes with anticarcinogenic activity.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Cells, Cultured; Coffee; Colorectal Neoplasms; Disease Models, Animal; Diterpenes; Enzyme Induction; Humans; Imidazoles | 2002 |
218 other study(ies) available for 9,10-dimethyl-1,2-benzanthracene and benzo(a)pyrene
| Article | Year |
|---|---|
Correlation between chemical suppression of natural killer cell activity in mice and susceptibility to cytomegalovirus: rationale for applying murine cytomegalovirus as a host resistance model and for interpreting immunotoxicity testing in terms of risk o
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Cadmium; Cadmium Chloride; Cells, Cultured; Chlorides; Cyclophosphamide; Cyclosporine; Cytomegalovirus Infections; Disease Susceptibility; Female; G(M1) Ganglioside; Immunity, Cellular; Immunosuppressive Agents; Killer Cells, Natural; Mice; Mice, Inbred C3H; Nickel; Polychlorinated Dibenzodioxins; Specific Pathogen-Free Organisms; Tetradecanoylphorbol Acetate | 1992 |
Polycyclic aromatic hydrocarbon metabolism in rat adrenal, ovary, and testis microsomes is catalyzed by the same novel cytochrome P450 (P450RAP).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Benzo(a)pyrene; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Gonadotropins, Equine; Hypophysectomy; Immunoblotting; Male; Microsomes; Ovary; Polycyclic Compounds; Rats; Rats, Sprague-Dawley; Testis | 1992 |
Inhibitory effects of curcumin on tumor initiation by benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Benzo(a)pyrene; Curcumin; DNA; Drug Antagonism; Female; Mice; Skin Neoplasms | 1992 |
Acceptance of class II major histocompatibility complex disparate skin grafts associated with suppressor cells and elevated Langerhans cell numbers.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Cell Count; Graft Survival; Histocompatibility Antigens Class II; Immunotherapy, Adoptive; Langerhans Cells; Lanolin; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Paraffin; Skin Transplantation; Spleen; T-Lymphocytes, Regulatory | 1992 |
Detection of PAH:DNA adducts from auto-oxidation using 32P-postlabeling.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Benz(a)Anthracenes; Benzo(a)pyrene; DNA; DNA Adducts; In Vitro Techniques; Oxidation-Reduction; Phosphorus Radioisotopes; Polycyclic Compounds | 1992 |
Carcinogenic and cocarcinogenic studies with carbaryl following topical exposure in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Benzo(a)pyrene; Carbaryl; Carcinogenicity Tests; Female; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Selective suppression of the catalytic activity of cDNA-expressed cytochrome P4502B1 toward polycyclic hydrocarbons in the microsomal membrane: modification of this effect by specific amino acid substitutions.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acids; Benzo(a)pyrene; Catalysis; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA; Genes, Viral; Humans; Intracellular Membranes; Microsomes, Liver; Mutation; Polycyclic Compounds; Protein Conformation; Recombinant Proteins; Testosterone; Tumor Cells, Cultured; Vaccinia virus | 1992 |
Chemopreventive effect of turmeric against stomach and skin tumors induced by chemical carcinogens in Swiss mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Curcumin; Diet; Female; Glutathione Transferase; Liver; Mice; Skin Neoplasms; Stomach Neoplasms | 1992 |
Inhibitory effect of topical application of a green tea polyphenol fraction on tumor initiation and promotion in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Benzo(a)pyrene; Edema; Enzyme Induction; Female; Flow Cytometry; Hydrogen Peroxide; Hyperplasia; Mice; Ornithine Decarboxylase; Phenols; Skin; Skin Neoplasms; Tea; Tetradecanoylphorbol Acetate | 1992 |
Decreased expression of the myristoylated alanine-rich C kinase substrate in transformed BALB/C 3T3 mouse fibroblasts.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Blotting, Southern; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; DNA Probes; Fibroblasts; Gene Expression; Humans; Intracellular Signaling Peptides and Proteins; Kirsten murine sarcoma virus; Membrane Proteins; Mice; Mice, Inbred BALB C; Myristoylated Alanine-Rich C Kinase Substrate; Protein Kinase C; Proteins; RNA; RNA, Messenger | 1991 |
Selections for and against cells possessing cytochrome P450IA1-dependent aryl hydrocarbon hydroxylase activity.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Carcinogens; Cell Line; Cell Survival; Culture Techniques; Cytochrome P-450 Enzyme System; Drug Resistance; Mutagenesis | 1991 |
Indomethacin inhibits the chemical carcinogen benzo(a)pyrene but not dimethylbenz(a)anthracene from altering Langerhans cell distribution and morphology.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Cell Count; Dinoprostone; Drug Implants; Indomethacin; Langerhans Cells; Male; Mice; Mice, Inbred BALB C; Microscopy, Electron; Skin | 1991 |
Inhibitory effects of coffee on the genotoxicity of carcinogens in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Bone Marrow; Carcinogens; Coffee; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Interactions; Male; Mice; Micronucleus Tests; Mutagenicity Tests; Mutation; Urethane | 1991 |
Effect of pH on the activity and stability of clastogens in the in vitro chromosomal aberration test with Chinese hamster ovary K1 cells.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Cells, Cultured; Chromatography, High Pressure Liquid; Chromosome Aberrations; Cricetinae; Culture Media; Dimethylnitrosamine; Female; Half-Life; Hydrogen-Ion Concentration; In Vitro Techniques; Methylnitronitrosoguanidine; Mitomycin; Mitomycins; Mutagens | 1991 |
Micronuclei in mouse skin cells following in vivo exposure to benzo[a]pyrene, 7,12-dimethylbenz[a]anthracene, chrysene, pyrene and urethane.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens; Chi-Square Distribution; Chrysenes; Mice; Mice, Hairless; Micronucleus Tests; Pyrenes; Skin; Time Factors; Urethane | 1991 |
Induction of chromosome aberrations and sister chromatid exchange by indirectly acting mutagens in immortal mouse and rat hepatocyte lines.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Biotransformation; Cell Line; Chromosome Aberrations; Cyclophosphamide; Liver; Mice; Mutagenicity Tests; Mutagens; Rats; Sister Chromatid Exchange | 1991 |
Inhibition of chemically-induced skin carcinogenesis in mice by peanut oil preparations.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Arachis; Benzo(a)pyrene; Female; Male; Mice; Mice, Inbred C3H; Ornithine Decarboxylase; Plant Oils; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
Potent inhibitory effects of suicide inhibitors of P450 isozymes on 7,12-dimethylbenz[a]anthracene and benzo[a]pyrene initiated skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Cytochrome P-450 Enzyme Inhibitors; DNA; Dose-Response Relationship, Drug; Isoenzymes; Mice; Naphthalenes; Polychlorinated Dibenzodioxins; Pyrenes; Skin Neoplasms | 1991 |
A role for prostaglandins in the suppression of cutaneous cellular immunity and tumour development in benzo(a)pyrene- but not dimethylbenz(a)anthracene-treated mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigen-Presenting Cells; Benzo(a)pyrene; Carcinoma, Squamous Cell; Dermatitis, Contact; Dinitrobenzenes; Immunity, Cellular; Indomethacin; Male; Mice; Mice, Inbred BALB C; Skin; Skin Neoplasms | 1991 |
Suppression of the in vitro humoral immune response of mouse splenocytes by 7,12-dimethylbenz[a]anthracene metabolites and inhibition of immunosuppression by alpha-naphthoflavone.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibody Formation; Benzo(a)pyrene; Benzoflavones; Cell Survival; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Erythrocytes; Female; Immunosuppressive Agents; Mice; Spleen | 1991 |
Influence of beta-myrcene on sister-chromatid exchanges induced by mutagens in V79 and HTC cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acyclic Monoterpenes; Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Biotransformation; Cell Line; Cricetinae; Cricetulus; Cyclophosphamide; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Monoterpenes; Mutagens; Sister Chromatid Exchange; Terpenes | 1991 |
Relationship between DNA adduct formation and unscheduled DNA synthesis (UDS) in cultured mouse epidermal keratinocytes.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Autoradiography; Benzo(a)pyrene; Cells, Cultured; DNA; DNA Replication; Epidermal Cells; Female; Isomerism; Keratinocytes; Mice; Mice, Inbred Strains; Mutagens; Tritium | 1991 |
Effects of ozonation on mutagenic activity of polycyclic aromatic hydrocarbons.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Benzo(a)pyrene; Biotransformation; Chromatography, High Pressure Liquid; Chrysenes; Fluorometry; Methylcholanthrene; Mutagenicity Tests; Ozone; Polycyclic Compounds; Salmonella typhimurium; Spectrophotometry, Ultraviolet | 1991 |
Comparative dose-response tumorigenicity studies of dibenzo[alpha,l]pyrene versus 7,12-dimethylbenz[alpha]anthracene, benzo[alpha]pyrene and two dibenzo[alpha,l]pyrene dihydrodiols in mouse skin and rat mammary gland.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogenicity Tests; Carcinogens; Dihydroxydihydrobenzopyrenes; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Mice; Skin Neoplasms | 1991 |
Distribution of constitutive and polycyclic aromatic hydrocarbon-induced cytochrome P-450 activities in murine epidermal cells that differ in their stages of differentiation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Calcium; Cell Differentiation; Cell Line; Cytochrome P-450 Enzyme System; Enzyme Induction; Epidermal Cells; Epidermis; Female; Keratinocytes; Kinetics; Mice; Mice, Inbred Strains; Mixed Function Oxygenases; Mutagenesis | 1991 |
Drosophila wing-spot test: improved detectability of genotoxicity of polycyclic aromatic hydrocarbons.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Drosophila melanogaster; Mutagenicity Tests; Mutagens; Polycyclic Compounds; Recombination, Genetic | 1990 |
The effect of complete carcinogens on intercellular transfer of lucifer yellow in fibroblast culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzoflavones; Carcinogens; Cell Line, Transformed; Cell Membrane Permeability; Cell Transformation, Viral; Cricetinae; Ethyl Methanesulfonate; Fibroblasts; Intercellular Junctions; Isoquinolines; Methylcholanthrene | 1990 |
Distribution of covalent DNA adducts in mouse epidermal subpopulations after topical application of benzo(a)pyrene and 7,12-dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Administration, Topical; Animals; Benzo(a)pyrene; Cell Separation; Chromatography, High Pressure Liquid; DNA; DNA Damage; Epidermal Cells; Epidermis; Mice; Time Factors | 1990 |
Inhibition of the binding of 7,12-dimethylbenz[a]anthracene and benzo[a]pyrene to DNA in mouse skin epidermis by 1-ethynylpyrene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Benzo(a)pyrene; DNA; Dose-Response Relationship, Drug; Mice; Naphthalenes; Pyrenes; Skin | 1990 |
Inhibition of meiotic divisions of rat spermatocytes in vitro by polycyclic aromatic hydrocarbons.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Biotransformation; Demecolcine; DNA; Flow Cytometry; Male; Meiosis; Rats; Rats, Inbred Strains; Spermatocytes; Vincristine | 1990 |
Acute inhibition of DNA synthesis in hamster buccal pouch epithelium exposed to indirect acting carcinogens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Carcinogens; Cell Division; Cricetinae; Dimethylnitrosamine; DNA; Male; Mesocricetus; Methylcholanthrene; Mouth Mucosa; Necrosis; Time Factors | 1990 |
Development of an optimal S9 activation mixture for the L5178Y TK+/- mouse lymphoma mutation assay.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Biotransformation; Cyclophosphamide; Dimethylnitrosamine; Lymphoma; Methylcholanthrene; Mice; Microsomes, Liver; Mutagenicity Tests; NADP; Thymidine Kinase; Time Factors; Tumor Cells, Cultured | 1990 |
Influence of effectors of prostaglandin metabolism on the toxicity induced by 7-hydroxymethyl-12-methylbenz(a)anthracene in cultured rat adrenal cells.
Topics: 5,8,11,14-Eicosatetraynoic Acid; 9,10-Dimethyl-1,2-benzanthracene; Adrenal Cortex; Animals; Arachidonic Acid; Arachidonic Acids; Benzo(a)pyrene; Bradykinin; Cells, Cultured; Dexamethasone; Drug Synergism; Hydrocortisone; Masoprocol; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats | 1990 |
Inhibition of experimental carcinogenesis by painting with garlic extract.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Analysis of Variance; Animals; Benzo(a)pyrene; Cheek; Cricetinae; DNA, Neoplasm; Garlic; Mesocricetus; Mouth Mucosa; Mouth Neoplasms; Nitroso Compounds; Plant Extracts; Plants, Medicinal; Pyrimidines | 1990 |
Characterization of a novel cytochrome P450 from the transformable cell line, C3H/10T1/2.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Cell Line, Transformed; Cytochrome P-450 Enzyme System; Epoxide Hydrolases; Immunoblotting; Isoenzymes; Mice; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Receptors, Drug | 1990 |
Interspecies comparison of human and rat mammary epithelial cell-mediated mutagenesis by polycyclic aromatic hydrocarbons.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Biotransformation; Breast; Breast Neoplasms; Carcinogens; Cells, Cultured; Epithelium; Female; Humans; Keratins; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mutation; Polycyclic Compounds; Rats; Rats, Inbred Strains; Species Specificity | 1986 |
Gap-junctional intercellular communication in epidermal cell lines from selected stages of SENCAR mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Calcium; Cell Communication; Cell Line; Epidermis; Intercellular Junctions; Keratins; Mice; Microinjections; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
Differential effects of benzo[a]pyrene and dimethylbenz[a]-anthracene on Langerhans cell distribution and contact sensitization in murine epidermis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens; Cell Count; Dermatitis, Contact; Dinitrofluorobenzene; Epidermal Cells; Epidermis; Female; Langerhans Cells; Mice; Mice, Inbred BALB C; Skin Neoplasms | 1989 |
Metabolic activation of polycyclic aromatic hydrocarbons to mutagens in the Ames test by various animal species including man.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Biotransformation; Cricetinae; Humans; Male; Mesocricetus; Methylcholanthrene; Mice; Mice, Inbred Strains; Mitochondria, Liver; Mutagenicity Tests; Polycyclic Compounds; Rats; Rats, Inbred Strains; Salmonella typhimurium; Swine | 1989 |
Protection against chemically induced skin tumorigenesis in SENCAR mice by tannic acid.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Cutaneous; Animals; Antineoplastic Agents, Phytogenic; Benzo(a)pyrene; Female; Hydrolyzable Tannins; Methylnitrosourea; Mice; Skin Neoplasms; Tannins | 1989 |
Effect of extracellular calcium concentration on the metabolism of polycyclic aromatic hydrocarbons by cultured mouse keratinocytes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Benzo(a)pyrene; Biotransformation; Calcium; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; DNA Damage; In Vitro Techniques; Keratinocytes; Mice; Mutation | 1989 |
Effect of dietary tannic acid on epidermal, lung, and forestomach polycyclic aromatic hydrocarbon metabolism and tumorigenicity in Sencar mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Cytosol; Diet; DNA; DNA Adducts; Female; Gastric Mucosa; Hydrolyzable Tannins; Lung; Lung Neoplasms; Mice; Microsomes; Skin; Skin Neoplasms; Stomach; Stomach Neoplasms; Tannins | 1989 |
Consistent oncogene methylation changes in epithelial cells chemically transformed in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Benzo(a)pyrene; Blotting, Southern; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Epithelial Cells; Epithelium; Genes, ras; Male; Methylation; Proto-Oncogenes; Rats; Rats, Inbred F344; Restriction Mapping; Tetradecanoylphorbol Acetate; Trachea | 1989 |
Inhibition of stage-specific DNA synthesis in rat spermatogenic cells by polycyclic aromatic hydrocarbons.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Cytochrome P-450 Enzyme Inhibitors; DNA; Free Radicals; Male; Microsomes; Mitochondria; Rats; Rats, Inbred Strains; Seminiferous Tubules; Spermatogenesis; Spermatozoa | 1989 |
Effects of 7,12-dimethylbenz[a]anthracene, benzo[a]pyrene and cyclosporin A on murine cytomegalovirus infection: studies of resistance mechanisms.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Cyclosporins; Cytomegalovirus Infections; Female; Killer Cells, Natural; Mice; T-Lymphocytes, Cytotoxic; Time Factors | 1988 |
Increased carcinogen metabolism and survival of retrovirus-infected Fischer rat embryo cells following repetitive carcinogen treatment.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Biotransformation; Carcinogens; Diethylnitrosamine; Embryo, Mammalian; Female; Kinetics; Pregnancy; Rats; Rats, Inbred F344 | 1985 |
Transplacental induction of a specific mutation in fetal Ha-ras and its critical role in post-natal carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinoma; Cocarcinogenesis; DNA, Neoplasm; Female; Mice; Mutation; Papilloma; Polymorphism, Restriction Fragment Length; Pregnancy; Prenatal Exposure Delayed Effects; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Proto-Oncogenes; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
Characterization of an epithelial, nearly diploid liver cell strain, from Chinese hamster, able to activate promutagens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Biotransformation; Cell Division; Cells, Cultured; Clone Cells; Cricetinae; Cricetulus; Epithelial Cells; Epithelium; Karyotyping; Liver; Mutagens; Pyruvate Kinase; Tyrosine Transaminase | 1987 |
Spontaneous and induced primary oncogenesis in natural killer (NK)-cell-deficient beige mutant mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinoma, Squamous Cell; Killer Cells, Natural; Leukemia Virus, Murine; Leukemia, Experimental; Lymphoma; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Rhabdomyosarcoma; Sarcoma; Tumor Virus Infections; Whole-Body Irradiation | 1985 |
Effects of arachidonic acid and indomethacin on sister-chromatid exchange induction by polycyclic aromatic hydrocarbons in mammalian cell lines.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arachidonic Acid; Arachidonic Acids; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Carcinoma, Hepatocellular; Cell Line; Cricetinae; Cricetulus; Drug Synergism; Enzyme Induction; Humans; Indomethacin; Liver Neoplasms; Rats; Sister Chromatid Exchange | 1986 |
Regulation of rat and bovine adrenal metabolism of polycyclic aromatic hydrocarbons by adrenocorticotropin and 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Benzo(a)pyrene; Cattle; Cells, Cultured; Chromatography, High Pressure Liquid; Dioxins; Male; Methylcholanthrene; Microsomes; Polychlorinated Dibenzodioxins; Polycyclic Compounds; Rats; Rats, Inbred Strains | 1986 |
Nuclease P1-mediated enhancement of sensitivity of 32P-postlabeling test for structurally diverse DNA adducts.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenosine Triphosphate; Animals; Benzo(a)pyrene; Carbazoles; Carcinogens; DNA; Female; Mice; Mice, Inbred Strains; Mitomycin; Mitomycins; Nucleotidases; Phosphorus Radioisotopes; Safrole; Single-Strand Specific DNA and RNA Endonucleases | 1986 |
Inhibitory effect of toluene on tumor promotion in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens; Cocarcinogenesis; Drug Antagonism; Male; Mice; Mice, Inbred C3H; Phorbols; Skin Neoplasms; Solvents; Tetradecanoylphorbol Acetate; Toluene | 1986 |
Augmentation of ethanol-induced enhancement of dimethylnitrosamine and diethylnitrosamine metabolism by lowered carbohydrate intake.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Cytochrome P-450 Enzyme System; Dietary Carbohydrates; Diethylnitrosamine; Dimethylnitrosamine; Ethanol; In Vitro Techniques; Kinetics; Liver; Male; Mutagenicity Tests; Proteins; Rats; Rats, Inbred Strains | 1986 |
A comparison of covalent DNA binding of benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene in respiratory tissues from human, rat and mouse.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Bronchi; DNA; Humans; Liver; Lung; Mice; Neoplasms, Experimental; Rats; Respiratory System; Trachea | 1986 |
Correlation between formation of a specific hydrocarbon-deoxyribonucleoside adduct and tumor-initiating activity of 7,12-dimethylbenz(a)anthracene and its 9- and 10-monofluoroderivatives in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenine; Animals; Benzo(a)pyrene; Biotransformation; Carcinogens; Chromatography, High Pressure Liquid; DNA; Epidermis; Mice; Papilloma; Skin Neoplasms; Structure-Activity Relationship | 1986 |
Analysis of the interlaboratory and intralaboratory reproducibility of the enhancement of simian adenovirus SA7 transformation of Syrian hamster embryo cells by model carcinogenic and noncarcinogenic compounds.
Topics: 2-Acetylaminofluorene; 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Adenoviridae; Adenoviruses, Simian; Animals; Benzo(a)pyrene; Carcinogens; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Chromates; Cocarcinogenesis; Cricetinae; Diethylnitrosamine; Dose-Response Relationship, Drug; Embryo, Mammalian; Lead; Mesocricetus; Methylnitronitrosoguanidine | 1986 |
Interspecies comparison of polycyclic aromatic hydrocarbon metabolism in human and rat mammary epithelial cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Breast; Carcinogens; Cell Count; Cells, Cultured; DNA; Epithelium; Female; Glucuronates; Humans; Individuality; Mammary Glands, Animal; Mutagens; Polycyclic Compounds; Rats; Rats, Inbred Strains; Species Specificity | 1986 |
Inhibition and enhancement of skin tumors in mice by dimethyl sulfoxide depending on method of application.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Dimethyl Sulfoxide; Drug Interactions; Male; Mice; Skin Neoplasms; Solvents; Tetradecanoylphorbol Acetate | 1986 |
The influence of bile on the bioavailability of polynuclear aromatic hydrocarbons from the rat intestine.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthracenes; Benzo(a)pyrene; Bile; Biological Availability; Intestinal Mucosa; Isomerism; Male; Naphthalenes; Phenanthrenes; Polycyclic Compounds; Rats; Rats, Inbred Strains | 1986 |
Quantitation of benzo(a)pyrene and 7,12-dimethylbenz(a)anthracene binding to nuclear macromolecules in human and rat mammary epithelial cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Cell Count; Cell Separation; DNA; Epithelium; Humans; Mammary Glands, Animal; Methods; Rats; Time Factors | 1987 |
Evaluation of Pluronic Polyol F127 as a vehicle for petroleum hydrocarbons in the Salmonella/microsomal assay.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alcohols; Benzo(a)pyrene; Cell Survival; Hydrocarbons; Methylcholanthrene; Microsomes, Liver; Mutagenicity Tests; Mutation; Petroleum; Poloxalene; Polyethylene Glycols; Salmonella typhimurium | 1987 |
Benzo(e)pyrene-induced alterations in the binding of benzo(a)pyrene and 7,12-dimethylbenz(a)anthracene to DNA in Sencar mouse epidermis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Cocarcinogenesis; DNA; Epidermis; Female; Mice; Skin Neoplasms | 1987 |
Interspecies differences in the major DNA adducts formed from benzo(a)pyrene but not 7,12-dimethylbenz(a)anthracene in rat and human mammary cell cultures.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Breast; Cells, Cultured; DNA; DNA Adducts; Female; Humans; Mammary Glands, Animal; Rats; Rats, Inbred Strains; Species Specificity | 1987 |
Further investigations into the effect of non-benzo ring bay-region methyl substituents on tumor-initiating activity of polycyclic hydrocarbons.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Female; Methylcholanthrene; Mice; Papilloma; Skin Neoplasms; Structure-Activity Relationship | 1987 |
Metabolism and DNA adduct formation of benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene in fish cell lines in culture.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Biotransformation; Cell Line; Cells, Cultured; Chromatography, High Pressure Liquid; Dihydroxydihydrobenzopyrenes; DNA; DNA Adducts; Fishes | 1987 |
Induction of contact hypersensitivity to dimethylbenz(a)anthracene and benzo(a)pyrene in C3H/HeN mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Dermatitis, Contact; Female; Immunization; Immunization, Passive; Kinetics; Mice; Mice, Inbred C3H; Skin | 1987 |
Effects of pretreatment with benzo[a]pyrene on the stereochemical selectivity of metabolic activation of benzo[a]pyrene to DNA-binding metabolites in hamster embryo cell cultures.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Biotransformation; Cells, Cultured; Cricetinae; Dactinomycin; DNA; Guanosine; Stereoisomerism | 1987 |
Catechin as an antimutagen: its mode of action.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Catechin; DNA; Male; Mutation; Nitroso Compounds; Rats; Rats, Inbred Strains | 1988 |
Exceptional activity of tannic acid among naturally occurring plant phenols in protecting against 7,12-dimethylbenz(a)anthracene-, benzo(a)pyrene-, 3-methylcholanthrene-, and N-methyl-N-nitrosourea-induced skin tumorigenesis in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Anthraquinones; Benzo(a)pyrene; DNA; Female; Flavonoids; Hydrolyzable Tannins; Methylcholanthrene; Methylnitrosourea; Mice; Mice, Inbred BALB C; Quercetin; Skin Neoplasms; Tannins | 1988 |
Survey of cytotoxicities and antimutagenic and antitumor initiating activities of Cu(II)(3,5-diisopropylsalicylate)2 and its analogs in a keratinocyte-mediated mutation assay and the murine skin multistage carcinogenesis model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Benzo(a)pyrene; Cell Line; Cell Survival; Cells, Cultured; Copper; Copper Sulfate; Epidermal Cells; Epidermis; Mice; Mice, Inbred Strains; Mutation; Papilloma; Salicylates; Skin Neoplasms | 1988 |
Intestinal absorption of carcinogenic hydrocarbons.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Bile Acids and Salts; Carcinogens; Hydrocarbons; Intestinal Absorption; Methylcholanthrene; Solubility | 1988 |
Differential effects of 7,8-benzoflavone on polycyclic aromatic hydrocarbon dependent mutagenesis and cytotoxicity in a keratinocyte cell-mediated mutation assay.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzoflavones; Biotransformation; Cells, Cultured; Cricetinae; Cricetulus; Epidermis; Flavonoids; Mice; Mutagenicity Tests; Mutagens | 1985 |
Cell-cell proximity is a parameter affecting the transfer of mutagenic polycyclic aromatic hydrocarbons between cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Cell Communication; Cells, Cultured; Cricetinae; Cricetulus; DNA; Mutagens; Polycyclic Compounds; Skin | 1985 |
Cross-reactive cellular and humoral immunity to carcinogen-induced chicken fibrosarcomas. I. Protective cross-immunity between transplantable tumor lines.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibodies, Neoplasm; Antibody Formation; Antigens, Neoplasm; Benzo(a)pyrene; Chickens; Cross Reactions; Fibrosarcoma; Graft Rejection; Hypersensitivity, Delayed; Immunity, Cellular; Methylcholanthrene; Neoplasm Transplantation; Sarcoma, Experimental | 1985 |
Comparative mutagenicity tests in the Salmonella/microsome assay with rat and woodchuck S9 preparations.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Biotransformation; Fluorenes; In Vitro Techniques; Marmota; Microsomes, Liver; Mutagenicity Tests; Mutagens; Rats; Rats, Inbred Strains; Salmonella typhimurium | 1985 |
Selective killing of carcinogen-treated SV40-transformed Chinese hamster cells by a defective parvovirus.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Survival; Cell Transformation, Viral; Cricetinae; Cricetulus; Defective Viruses; Kinetics; Parvoviridae; Simian virus 40 | 1984 |
The effectiveness of chemical carcinogens to induce atherosclerosis in the white Carneau pigeon.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aorta, Abdominal; Arteriosclerosis; Benzo(a)pyrene; Benzopyrenes; Blood Pressure; Carcinogens; Chlorophenols; Cholesterol; Columbidae; Lipoproteins, HDL; Lipoproteins, LDL; Male; Methylcholanthrene | 1984 |
Glyoxalase I in regenerating mouse liver exposed to carcinogens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Carcinogens; DNA Replication; Enzyme Induction; Female; Kinetics; Lactoylglutathione Lyase; Liver; Liver Regeneration; Lyases; Mice | 1983 |
The influence of polycyclic hydrocarbons on the activity of NAD(P)H-dehydrogenating enzymes in rat thymus. A biochemical and histochemical study.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenalectomy; Animals; Benzo(a)pyrene; Benzopyrenes; Dicumarol; Methylcholanthrene; NADH, NADPH Oxidoreductases; NADPH-Ferrihemoprotein Reductase; Polycyclic Compounds; Quinone Reductases; Rats; Thymus Gland | 1983 |
Metabolism of benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene in chicken aortas: monooxygenation, bioactivation to mutagens, and covalent binding to DNA in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aorta; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Blood Vessels; Chickens; DNA; Kinetics; Male; Mutagens; Salmonella typhimurium; Time Factors | 1980 |
Chromosome abnormalities associated with salivary gland epithelial cell lines transformed in vitro and in vivo with evidence of a role for genetic imbalance in transformation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Cell Line; Cell Transformation, Neoplastic; Chromosome Aberrations; Epithelium; Karyotyping; Male; Mice; Neoplasms, Experimental; Phenotype; Salivary Glands | 1981 |
Inhibition of benzo(a)pyrene-induced transformation of C3H/10T1/2 cells by allylisopropylacetamide and isopropylvaleramide.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetamides; Allylisopropylacetamide; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Cell Transformation, Neoplastic; Cells, Cultured; Mice; Time Factors | 1981 |
Further investigations of the capacity of polynuclear aromatic hydrocarbons to elicit atherosclerotic lesions.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aorta, Abdominal; Arteriosclerosis; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Chickens; Polycyclic Compounds; Tetradecanoylphorbol Acetate | 1981 |
Rat bladder cell-mediated mutagenesis od Chinese hamster V79 cells and metabolism of benzo[a]pyrene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Line; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; Cytological Techniques; Dimethylnitrosamine; Epithelium; Male; Mutagens; Rats; Urinary Bladder | 1981 |
Comparison of the tumor-initiating activity of 7,12-dimethylbenz[a]anthracene and benzo[a]pyrene in female SENCAR and CS-1 mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Dose-Response Relationship, Drug; Drug Resistance; Female; Mice; Neoplasms, Experimental; Oxidation-Reduction; Skin; Skin Neoplasms; Species Specificity | 1980 |
Rat hepatocyte-mediated mutagenesis of human cells by carcinogenic polycyclic aromatic hydrocarbons but not organochlorine pesticides.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Cells, Cultured; Humans; Hydrocarbons, Chlorinated; Hypoxanthine Phosphoribosyltransferase; Insecticides; Liver; Male; Mutagenicity Tests; Mutation; Rats; Skin | 1981 |
Modulation of the covalent binding of aryl hydrocarbon metabolites to DNA in vitro after treatment of rats and mice with trans-stilbene oxide.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; DNA; Epoxide Hydrolases; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Microsomes, Liver; Polycyclic Compounds; Rats; Rats, Inbred Strains; Stilbenes | 1981 |
Cytotoxic effects and metabolism of benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene in duodenal and ileal epithelial cell cultures.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Division; Cell Line; Duodenum; Epithelium; Germ-Free Life; Ileum; Microscopy, Electron; Rats | 1981 |
A clinically relevant canine lung cancer model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Delayed-Action Preparations; Disease Models, Animal; Dogs; Lung Neoplasms; Methods; Methylcholanthrene; Methylnitrosourea; Neoplasms, Experimental; Radioisotopes; Tetradecanoylphorbol Acetate | 1981 |
The metabolism and activation of polycyclic aromatic hydrocarbons in epithelial cell aggregates and fibroblasts prepared from rat mammary tissue.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Cells, Cultured; Chromatography, High Pressure Liquid; DNA; Epithelium; Female; Mammary Glands, Animal; Polycyclic Compounds; Protein Binding; Rats; Rats, Inbred Strains; Skin | 1982 |
DNA modification and repair in the experimental induction of nervous system tumors by chemical carcinogens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkylation; Animals; Benzo(a)pyrene; Benzopyrenes; DNA Repair; DNA, Neoplasm; Fetus; Hydrazines; Neoplasms, Experimental; Nervous System Neoplasms; Nitrosourea Compounds; Polycyclic Compounds; Rats; Triazenes | 1982 |
Anticarcinogenic and cocarcinogenic effects of benzo[e]pyrene and dibenz[a,c]anthracene on skin tumor initiation by polycyclic hydrocarbons.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; DNA; Drug Interactions; Female; Methylcholanthrene; Mice; Mice, Inbred Strains; Skin Neoplasms | 1982 |
Differential effects of retinoic acid and 7,8-benzoflavone on the induction of mouse skin tumors by the complete carcinogenesis process and by the initiation-promotion regimen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; Dose-Response Relationship, Drug; Enzyme Induction; Female; Flavonoids; Injections, Intraperitoneal; Methylcholanthrene; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1982 |
Effects of polycyclic hydrocarbons on the induction of chromosomal aberrations in absence of an exogenous metabolic activation system in cultured hamster cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Cell Line; Chromosome Aberrations; Chromosomes; Cricetinae; Cricetulus; Methylcholanthrene; Polycyclic Compounds | 1982 |
Chemical carcinogen activation in the rat mammary gland: intra-organ cell specificity.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Carcinogens; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Organ Specificity; Rats; Rats, Inbred Strains | 1982 |
Human breast cell-mediated mutagenesis of mammalian cells by polycyclic aromatic hydrocarbons.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Breast; Cell Line; Cells, Cultured; Cricetinae; Cricetulus; Epithelium; Female; Humans; Lung; Mammary Glands, Animal; Mutagenicity Tests; Mutagens; Mutation; Rats | 1982 |
Benzo(a)pyrene and 7,12-dimethylbenz(a)anthracene metabolism and DNA adduct formation in primary cultures of hamster epidermal cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Cells, Cultured; Chromatography, High Pressure Liquid; Cricetinae; DNA; Epidermis; Mesocricetus | 1983 |
Epigenetic membrane effects of a possible tumor promoting type on cultured liver cells by the non-genotoxic organochlorine pesticides chlordane and heptachlor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Communication; Chlordan; Heptachlor; Hypoxanthine Phosphoribosyltransferase; Liver; Male; Mutagenicity Tests; Mutagens; Mutation; Rats; Rats, Inbred F344 | 1982 |
Preferential binding of polycyclic hydrocarbons to matrix-bound DNA in rat-liver nuclei.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Nucleus; Chromatin; DNA; Kinetics; Liver; Male; Rats; Rats, Inbred Strains | 1983 |
Metabolism of polycyclic aromatic hydrocarbons in the rat ovary. Comparison with metabolism in adrenal and liver tissues.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Glands; Animals; Benzo(a)pyrene; Benzopyrenes; Epoxide Hydrolases; Female; Glutathione Transferase; In Vitro Techniques; Liver; NAD(P)H Dehydrogenase (Quinone); Organ Specificity; Ovary; Polycyclic Compounds; Quinone Reductases; Rats; Rats, Inbred Strains; Subcellular Fractions | 1983 |
Relationship of benign papillomas to cancer induction in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Dose-Response Relationship, Drug; Mice; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1981 |
Effect of vitamin A palmitate on mutagenesis induced by polycyclic aromatic hydrocarbons in human cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Cell Line; Cell Survival; Diterpenes; Epithelium; Humans; Methylcholanthrene; Mutagenicity Tests; Mutagens; Retinyl Esters; Vitamin A | 1983 |
Relationship of mammary tumor susceptibility, mammary cell-mediated mutagenesis, and metabolism of polycyclic aromatic hydrocarbons in four types of rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Female; Mammary Neoplasms, Experimental; Mutagens; Mutation; Polycyclic Compounds; Rats; Rats, Inbred F344; Rats, Inbred Strains; Species Specificity | 1983 |
In vitro cultivation of embryonic rat tongue cells--a convenient system for oral carcinogenesis studies.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Division; Cells, Cultured; Cheek; Cricetinae; Drug Evaluation, Preclinical; Female; Mesocricetus; Methylnitronitrosoguanidine; Pregnancy; Rats; Rats, Inbred Strains; Tongue | 1983 |
In vitro induction of malignant transformation and in vivo resistance to tumor growth in the X/Gf mouse.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Agar; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Cell Transformation, Neoplastic; Cells, Cultured; Embryo, Mammalian; Female; Male; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Sarcoma, Experimental | 1983 |
Initiation/promotion studies with coal-derived liquids.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Coal; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Skin Neoplasms | 1983 |
Inhibitory effect of 7,8-benzoflavone on DMBA- and BaP-induced bone marrow micronuclei in mouse.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; Bone Marrow; Cell Nucleus; Chromosomes; Female; Flavonoids; Mice; Time Factors | 1983 |
Comparison of aryl hydrocarbon hydroxylase activity and inducibility of sister-chromatid exchanges by polycyclic aromatic hydrocarbons in mammalian cell lines.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzopyrenes; Cell Line; Cricetinae; Cricetulus; Crossing Over, Genetic; Humans; Methylcholanthrene; Polycyclic Compounds; Rats; Sister Chromatid Exchange | 1983 |
An intestinal cell-mediated chromosome aberration test for the detection of genotoxic agents.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Cell Cycle; Cell Line; Cells, Cultured; Chromosome Aberrations; Cricetinae; Cricetulus; Female; Intestinal Mucosa; Intestine, Small; Kinetics; Mice; Mice, Inbred Strains; Microsomes, Liver; Mutagenicity Tests; Mutagens; Mutation; Ovary; Rats | 1983 |
Products of binding of 7,12-dimethylbenz(a)anthracene to DNA in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Carcinogens; Cells, Cultured; DNA; Embryo, Mammalian; Female; Kinetics; Male; Mice; Skin; Tritium | 1983 |
Activation of polycyclic hydrocarbons in Reuber H4-II-E hepatoma cells. An in vitro system for the induction of SCEs.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Crossing Over, Genetic; In Vitro Techniques; Kinetics; Liver Neoplasms, Experimental; Methylcholanthrene; Mutagens; Polycyclic Compounds; Sister Chromatid Exchange; Structure-Activity Relationship | 1983 |
Protective effects of ellagic acid and other plant phenols on benzo[a]pyrene-induced neoplasia in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Benzo(a)pyrene; Benzopyrans; Benzopyrenes; Carcinogens; Chlorogenic Acid; Cinnamates; Coumaric Acids; Ellagic Acid; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Plants, Medicinal; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1983 |
Highly persistent polycyclic aromatic hydrocarbon-DNA adducts in mouse skin: detection by 32P-postlabeling analysis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Transformation, Neoplastic; DNA; DNA Repair; DNA, Neoplasm; Female; Isotope Labeling; Methylcholanthrene; Mice; Mice, Inbred BALB C; Phosphorus Radioisotopes; Polycyclic Compounds; Skin | 1983 |
The in vivo uptake of tritiated thymidine as a potential short-term test of toxic effects of polycyclic aromatic hydrocarbons in different organs.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthracenes; Autoradiography; Benzo(a)pyrene; Benzopyrenes; Male; Mice; Thymidine; Tissue Distribution; Tritium | 1984 |
Metabolism of xenobiotics in the human adrenal gland.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Cortex; Aryl Hydrocarbon Hydroxylases; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Cytochrome P-450 Enzyme System; Epoxide Hydrolases; Female; Glutathione Transferase; Humans; Male; Microsomes; Mitochondria | 1984 |
Benzo(e)pyrene-induced alterations in the metabolic activation of benzo(a)pyrene and 7,12-dimethylbenz(a)anthracene by hamster embryo cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Carcinogens; Cell Line; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; Embryo, Mammalian; Lung; Mesocricetus; Mutation | 1984 |
Murine susceptibility to two-stage skin carcinogenesis is influenced by the agent used for promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Carcinogens; Cell Line; Cricetinae; Cricetulus; Female; Lung; Mice; Mice, Inbred Strains; Mutagenicity Tests; Mutagens; Mutation; Skin; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1984 |
Percutaneous absorption of [7.10-14C]benzo[a]pyrene and [7,12-14C]dimethylbenz[a]anthracene in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Carbon Radioisotopes; Feces; Mice; Skin Absorption | 1984 |
Cytotoxicity of chemical carcinogens towards human bronchial epithelial cells evaluated in a clonal assay.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult; Aged; Benzo(a)pyrene; Bronchi; Carcinogens; Cells, Cultured; Chromates; Epithelium; Female; Humans; Male; Methylnitronitrosoguanidine; Middle Aged; Potassium Compounds | 1984 |
Binding and metabolism of benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene by seven purified forms of cytochrome P-450.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Cytochrome P-450 Enzyme System; Enzyme Induction; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Spectrophotometry; Substrate Specificity | 1984 |
Metabolic activation of procarcinogens to genotoxic products in cultured rat liver cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Biotransformation; Carcinogens; Cell Survival; Cyclophosphamide; Liver; Liver Neoplasms, Experimental; Rats; Sister Chromatid Exchange | 1984 |
Polycyclic aromatic hydrocarbon mutagenesis of human epidermal keratinocytes in culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Benzo(a)pyrene; Cell Line; Clone Cells; Humans; Hypoxanthine Phosphoribosyltransferase; Mutagens; Phenotype; Skin | 1984 |
Todralazine influence upon the mutagenicity of some direct- and indirect-acting mutagens.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Aminacrine; Antimutagenic Agents; Azides; Benzo(a)pyrene; Biotransformation; Daunorubicin; Dose-Response Relationship, Drug; Methyl Methanesulfonate; Methylcholanthrene; Microsomes, Liver; Mitomycin; Mutagenicity Tests; Mutagens; Salmonella typhimurium; Sodium Azide; Todralazine | 1994 |
Induction of micronuclei and sister chromatid exchanges by polycyclic and N-heterocyclic aromatic hydrocarbons in cultured human lymphocytes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult; Benz(a)Anthracenes; Benzo(a)pyrene; Carbazoles; Carcinogens; Cell Division; Cells, Cultured; DNA Adducts; Dose-Response Relationship, Drug; Environmental Pollutants; Female; Heterocyclic Compounds; Humans; Male; Micronuclei, Chromosome-Defective; Micronucleus Tests; Polycyclic Aromatic Hydrocarbons; Sister Chromatid Exchange; Structure-Activity Relationship; T-Lymphocytes | 1995 |
Genotoxic potency in Drosophila melanogaster of selected aromatic amines and polycyclic aromatic hydrocarbons as assayed in the DNA repair test.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Amines; Animals; Anthracenes; Benz(a)Anthracenes; Benzo(a)pyrene; DNA Repair; Dose-Response Relationship, Drug; Drosophila melanogaster; Female; Fluorenes; Genes, Insect; Larva; Male; Methylcholanthrene; Mutagens; Polycyclic Compounds; Pyrenes; Sex Ratio | 1993 |
Abrogation of afferent lymph dendritic cell function after cutaneously applied chemical carcinogens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Cutaneous; Animals; Antigen Presentation; Benzo(a)pyrene; Carcinogens; Cell Movement; Dendritic Cells; Flow Cytometry; Lymphatic System; Lymphocyte Activation; Ovalbumin; Sheep; Skin; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1995 |
Induction of micronuclei in metabolically competent rat hepatoma cell lines by the promutagens 7,12-dimethylbenz[a]anthracene, benzo[a]pyrene and cyclophosphamide.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Biotransformation; Cyclophosphamide; Liver Neoplasms, Experimental; Male; Micronucleus Tests; Mitomycin; Mutagens; Prodrugs; Rats; Tumor Cells, Cultured | 1995 |
Polycyclic aromatic hydrocarbons decrease intracellular glutathione levels in the A20.1 murine B cell lymphoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Calcium; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Glutathione; Lymphoma, B-Cell; Mice; Polycyclic Compounds; Tumor Cells, Cultured | 1994 |
Selective down-regulation of protein kinase c-epsilon by carcinogens does not prevent stimulation of phospholipase D by phorbol ester and platelet-derived growth factor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkaloids; Animals; Benzo(a)pyrene; Carcinogens; Cell Line; Isoenzymes; Mice; Mice, Inbred C3H; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Platelet-Derived Growth Factor; Protein Kinase C; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Hormone receptors and cathepsin D levels in human breast epithelial cells transformed by chemical carcinogens and c-Ha-ras transfection.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Breast; Breast Neoplasms; Cathepsin D; Cell Line, Transformed; Cell Transformation, Neoplastic; Chemotaxis; Clone Cells; Epithelium; ErbB Receptors; Female; Genes, ras; Humans; Mice; Mice, SCID; Neoplasm Invasiveness; Receptors, Cell Surface; Receptors, Estrogen; Receptors, Progesterone; Transfection; Transplantation, Heterologous | 1994 |
Metabolism of benzo(a)pyrene, dimethylbenzanthracene and aflatoxin B1 by camel liver microsomes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Animals; Benzo(a)pyrene; Camelus; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Inactivation, Metabolic; Male; Microsomes, Liver; Rats | 1994 |
Inhibition of two-stage skin carcinogenesis as well as complete skin carcinogenesis by oral administration of TMK688, a potent lipoxygenase inhibitor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Administration, Topical; Animals; Anticarcinogenic Agents; Arachidonate Lipoxygenases; Benzo(a)pyrene; Female; Indomethacin; Lipoxygenase Inhibitors; Mice; Mice, Inbred Strains; Piperidines; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1994 |
Analysis of polycyclic aromatic hydrocarbon-DNA adducts by postlabelling with the weak beta-emitters 35S-phosphorothioate and 33P-phosphate, immobilized boronate chromatography and high-performance liquid chromatography.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens; Cells, Cultured; Chromatography, High Pressure Liquid; Cricetinae; DNA; DNA Adducts; DNA Damage; Phosphorus Radioisotopes; Polycyclic Compounds; Stereoisomerism; Sulfur Radioisotopes; Thionucleotides | 1993 |
Characterization of benzo[a]pyrene-initiated mouse skin papillomas for Ha-ras mutations and protein kinase C levels.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Base Sequence; Benzo(a)pyrene; Codon; DNA, Neoplasm; Epidermis; Female; Genes, ras; Isoenzymes; Mice; Mice, Inbred Strains; Molecular Sequence Data; Oligodeoxyribonucleotides; Papilloma; Point Mutation; Protein Kinase C; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
Carcinogens stimulate phosphorylation of ethanolamine derived from increased hydrolysis of phosphatidylethanolamine in C3H/101/2 fibroblasts.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens; Cell Line; Ethanolamines; Hydrolysis; Mice; Mice, Inbred C3H; Phosphatidylethanolamines; Phosphorylation; Phosphorylcholine; Phosphotransferases (Alcohol Group Acceptor) | 1993 |
Inhibition of skin tumorigenesis by rosemary and its constituents carnosol and ursolic acid.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Abietanes; Animals; Anticarcinogenic Agents; Antioxidants; Arachidonic Acid; Benzo(a)pyrene; Dermatitis, Contact; DNA; Drug Interactions; Enzyme Induction; Epidermis; Female; Hyperplasia; Magnoliopsida; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Phenanthrenes; Plant Extracts; Skin; Skin Neoplasms; Spices; Tetradecanoylphorbol Acetate; Triterpenes; Tritium; Ursolic Acid | 1994 |
Exceptional tumor-initiating activity of 4-fluorobenzo[j]-fluoranthene on mouse skin: comparison with benzo[j]-fluoranthene, 10-fluoro-benzo[j]fluoranthene, benzo[a]pyrene, dibenzo[a,l]pyrene and 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Female; Fluorenes; Mice; Skin Neoplasms | 1993 |
Benzo[a]pyrene-induced murine skin tumors exhibit frequent and characteristic G to T mutations in the p53 gene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinoma, Squamous Cell; Genes, Tumor Suppressor; Heterozygote; Immunohistochemistry; Mice; Mutation; Neoplasms, Experimental; Papilloma; Point Mutation; Polymerase Chain Reaction; Skin Neoplasms; Tumor Suppressor Protein p53 | 1993 |
12-O-tetradecanoylphorbol-13-acetate-mediated systemic co-promotion in the murine skin multistage carcinogenesis protocol.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens; Female; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
Cytogenetic effects of promutagens in genetically engineered V79 Chinese hamster cells expressing cytochromes P450.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Animals; Benzo(a)pyrene; Biotransformation; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; Cyclophosphamide; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Genetic Engineering; Mutagens; Rats; Sister Chromatid Exchange | 1993 |
Tumor-initiating activity and carcinogenicity of dibenzo[a,l]pyrene versus 7,12-dimethylbenz[a]anthracene and benzo[a]pyrene at low doses in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Carcinoma; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred Strains; Papilloma; Sebaceous Gland Neoplasms; Skin Neoplasms; Time Factors | 1993 |
The contribution of excision repair to the DNA effects seen in the alkaline single cell gel test (comet assay).
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Aphidicolin; Benzo(a)pyrene; Cell Survival; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Enzyme Inhibitors; Fibroblasts; Humans; Male; Mutagens; Ultraviolet Rays; Xeroderma Pigmentosum | 1995 |
Effect of eugenol on the genotoxicity of established mutagens in the liver.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Animals; Antimutagenic Agents; Benzo(a)pyrene; Carcinoma, Hepatocellular; Cytochrome P-450 Enzyme System; DNA; Electrophoresis, Agar Gel; Eugenol; Glutathione Transferase; Humans; Liver; Liver Neoplasms; Male; Micronucleus Tests; Mutagenicity Tests; Mutagens; Rats; Rats, Wistar; Salmonella typhimurium; Tumor Cells, Cultured | 1996 |
Fetal mouse susceptibility to transplacental carcinogenesis: differential influence of Ah receptor phenotype on effects of 3-methylcholanthrene, 12-dimethylbenz[a]anthracene, and benzo[a]pyrene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens; Crosses, Genetic; Female; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Maternal-Fetal Exchange; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Pharmacogenetics; Phenotype; Pregnancy; Receptors, Aryl Hydrocarbon; Risk Factors | 1995 |
Uptake of 7,12-dimethylbenz(a)anthracene and benzo(a)pyrene in melanin-containing tissues.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Glands; Animals; Autoradiography; Benzo(a)pyrene; Bone Marrow; Brain; Carbon Radioisotopes; Carcinogens; Cricetinae; Eye; Female; Heart; Image Processing, Computer-Assisted; Isotope Labeling; Kidney; Liver; Lung; Male; Melanins; Mesocricetus; Mice; Mice, Inbred C57BL; Myocardium; Spleen; Tissue Distribution | 1996 |
Inhibitory effect of TMK688 on skin tumor initiation caused by 7,12-dimethylbenz[a]anthracene in relation to inhibition of aryl hydrocarbon hydroxylase activity and Cyp1a1 mRNA induction.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Base Sequence; Benzo(a)pyrene; Carcinogens; Cytochrome P-450 CYP1A1; Dose-Response Relationship, Drug; Enzyme Induction; Epidermis; Female; Gene Expression Regulation, Enzymologic; Lipoxygenase Inhibitors; Mice; Piperidines; RNA, Messenger; Skin Neoplasms | 1996 |
Genetics of chemical carcinogenesis--III. Tissue-specificity of the genes controlling susceptibility and resistance to skin carcinogenesis in the mouse.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens; Cocarcinogenesis; Disease Susceptibility; Female; Immunity, Innate; Injections, Subcutaneous; Male; Mice; Mice, Inbred Strains; Organ Specificity; Sensitivity and Specificity; Skin; Skin Neoplasms; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate | 1996 |
Inhibitory effects of naturally occurring coumarins on the metabolic activation of benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene in cultured mouse keratinocytes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Biotransformation; Carcinogens; Cell Line; Coumarins; DNA Adducts; Female; Furocoumarins; Humans; Keratinocytes; Mice | 1997 |
Increased expression of G1 cyclins and cyclin-dependent kinases during tumor progression of chemically induced mouse skin neoplasms.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens; Carcinoma, Squamous Cell; Cell Cycle; Cyclin D1; Cyclin D2; Cyclin D3; Cyclin-Dependent Kinases; Cyclins; G1 Phase; Gene Expression Regulation, Neoplastic; Immunohistochemistry; Mice; Oncogene Proteins; Papilloma; S Phase; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
32P-Postlabeling high-performance liquid chromatographic improvements to characterize DNA adduct stereoisomers from benzo[a]pyrene and benzo[c]phenanthrene, and to separate DNA adducts from 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens; Cattle; Chromatography, High Pressure Liquid; Deoxyadenosines; Deoxyguanosine; DNA Adducts; Mutagens; Phenanthrenes; Phosphorus Radioisotopes; Reproducibility of Results; Stereoisomerism | 1997 |
Failure of carcinogen-altered dendritic cells to initiate T cell proliferation is associated with reduced IL-1 beta secretion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigen Presentation; Benzo(a)pyrene; Carcinogens; Dendritic Cells; Interleukin-1; Lymph; Lymphocyte Activation; Sheep; Skin; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1997 |
Ornithine decarboxylase overexpression is a sufficient condition for tumor promotion in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animals; Animals, Newborn; Benzo(a)pyrene; Hair Follicle; Immunohistochemistry; Methylnitronitrosoguanidine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Ornithine Decarboxylase; Putrescine; Skin; Skin Neoplasms; Spermidine; Tetradecanoylphorbol Acetate; Time Factors | 1997 |
Carcinogenic polycyclic aromatic hydrocarbons increase intracellular Ca2+ and cell proliferation in primary human mammary epithelial cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Benzo(a)pyrene; Benzoflavones; Breast; Breast Neoplasms; Calcium; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Epithelium; Female; Homeostasis; Humans; Intracellular Fluid; Polychlorinated Dibenzodioxins; Polycyclic Aromatic Hydrocarbons | 1997 |
Characterization of intracellular calcium responses produced by polycyclic aromatic hydrocarbons in surface marker-defined human peripheral blood mononuclear cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult; Antigens, CD; B-Lymphocyte Subsets; Benzo(a)pyrene; Calcium; Humans; Immunosuppressive Agents; Intracellular Fluid; Leukocytes, Mononuclear; Polycyclic Aromatic Hydrocarbons; T-Lymphocyte Subsets; Time Factors | 1997 |
[Organ cytotoxicity of selected polycyclic aromatic hydrocarbons in mice].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens; Dimethyl Sulfoxide; Female; Kidney; Liver; Lymphoid Tissue; Methylcholanthrene; Mice; Mice, Inbred BALB C; Nucleolus Organizer Region; Organ Size; Polycyclic Compounds | 1997 |
Effect of naturally occurring coumarins on the formation of epidermal DNA adducts and skin tumors induced by benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Coumarins; DNA Adducts; Dose-Response Relationship, Drug; Epidermis; Furocoumarins; Mice; Mice, Inbred SENCAR; Skin Neoplasms; Survival Rate; Tetradecanoylphorbol Acetate; Umbelliferones | 1997 |
Tissue distribution of DNA adducts in rats treated by intramammillary injection with dibenzo[a,l]pyrene, 7,12-dimethylbenz[a]anthracene and benzo[a]pyrene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; DNA; DNA Adducts; Female; Mammary Glands, Animal; Mutagens; Phosphorus Radioisotopes; Rats; Rats, Sprague-Dawley; Tissue Distribution; Tumor Cells, Cultured | 1997 |
Determination of benzo[a]pyrene- and 7,12-dimethylbenz[a]anthracene-DNA adducts formed in rat mammary glands.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens; Chromatography, High Pressure Liquid; DNA Adducts; Female; Mammary Glands, Animal; Phosphorus Radioisotopes; Rats; Rats, Sprague-Dawley | 1997 |
Evaluation of positive controls for the in vitro unscheduled DNA synthesis assay using hepatocytes from induced (Aroclor 1254) and uninduced male cynomolgus monkey.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aroclors; Benzo(a)pyrene; Biotransformation; Dimethylnitrosamine; DNA Repair; Enzyme Induction; Liver; Macaca fascicularis; Male; Methyl Methanesulfonate; Mutagenicity Tests | 1997 |
Aneuploidy induction by benzo[a]pyrene and polyploidy induction by 7,12-dimethylbenz[a]anthracene in Chinese hamster cell lines V79-MZ and V79.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aneuploidy; Animals; Benzo(a)pyrene; Cell Cycle; Cell Line; CHO Cells; Chromosome Aberrations; Colchicine; Cricetinae; Cricetulus; Methylcholanthrene; Mitomycin; Mutagens; Polyploidy; Sister Chromatid Exchange | 1997 |
Comparison of alkaline single cell gel (Comet) and peripheral blood micronucleus assays in detecting DNA damage caused by direct and indirect acting mutagens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Cyclophosphamide; DNA Damage; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Lymphocytes; Male; Methyl Methanesulfonate; Methylnitrosourea; Mice; Mice, Inbred Strains; Micronucleus Tests; Mitomycin; Mutagenicity Tests; Mutagens; Sensitivity and Specificity | 1997 |
Comparison of immunoaffinity chromatography enrichment and nuclease P1 procedures for 32P-postlabelling analysis of PAH-DNA adducts.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibodies, Monoclonal; Benzo(a)pyrene; Carcinogens; Chromatography, Affinity; Chrysenes; DNA Adducts; Fluorescent Antibody Technique; Isotope Labeling; Mice; Mutagenicity Tests; Mutagens; Phosphorus Radioisotopes; Polycyclic Aromatic Hydrocarbons; Single-Strand Specific DNA and RNA Endonucleases; Skin | 1998 |
Increased expression of estrogen receptor beta in chemically transformed human breast epithelial cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Benzo(a)pyrene; Breast; Carcinogens; Cell Line; Cell Line, Transformed; Epithelial Cells; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Gene Expression; Genes, ras; Genetic Variation; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Polymerase Chain Reaction; Receptors, Estrogen; RNA, Messenger; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1998 |
Spontaneous and asbestos-induced transformation of mesothelial cells in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Asbestos; Benzo(a)pyrene; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Epithelial Cells; Insulin; Insulin-Like Growth Factor I; Pleura; Rats; Rats, Wistar | 1998 |
Spindle disturbances induced by benzo[a]pyrene and 7, 12-dimethylbenz[a]anthracene in a Chinese hamster cell line (V79-MZ) and the stability of the numerical chromosome aberrations that follow.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aneuploidy; Animals; Benzo(a)pyrene; Cell Line; Cricetinae; Cricetulus; Polyploidy; Spindle Apparatus; Time Factors | 1998 |
Antitumour activity of diallyl sulfide on polycyclic aromatic hydrocarbon-induced mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Allyl Compounds; Animals; Antineoplastic Agents; Benzo(a)pyrene; Female; Mice; Skin Neoplasms; Sulfides; Time Factors | 1998 |
Contribution of theafulvins to the antimutagenicity of black tea: their mechanism of action.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antimutagenic Agents; Benzo(a)pyrene; Carcinogens; Catechin; Chlorodiphenyl (54% Chlorine); Dose-Response Relationship, Drug; Imidazoles; Male; Microsomes, Liver; N-Nitrosopyrrolidine; Nitrosamines; Oxazines; Phenols; Polyphenols; Quinolines; Rats; Rats, Wistar; Tea; Vitamin K | 1998 |
Escherichia coli MTC, a human NADPH P450 reductase competent mutagenicity tester strain for the expression of human cytochrome P450 isoforms 1A1, 1A2, 2A6, 3A4, or 3A5: catalytic activities and mutagenicity studies.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Cloning, Molecular; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Escherichia coli; Humans; Kinetics; Mixed Function Oxygenases; Mutagenicity Tests; Mutagens; NADPH-Ferrihemoprotein Reductase; Rats; Recombinant Proteins | 1999 |
A proposal for a simple way to distinguish aneugens from clastogens in the in vitro micronucleus test.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aneuploidy; Animals; Benzo(a)pyrene; Cell Line; Cricetinae; Cricetulus; Diazepam; Methylnitronitrosoguanidine; Micronucleus Tests; Mitomycin; Mutagens; Vincristine | 1999 |
Regulation of preB cell apoptosis by aryl hydrocarbon receptor/transcription factor-expressing stromal/adherent cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; B-Lymphocytes; Benzo(a)pyrene; Benzoflavones; Bone Marrow Cells; Cell Line; DNA Fragmentation; Flow Cytometry; Gene Expression Regulation; Hematopoiesis; Liver; Mice; Mice, Knockout; Polycyclic Aromatic Hydrocarbons; Receptors, Aryl Hydrocarbon; RNA, Messenger; Stromal Cells; Transcription Factors | 1999 |
Induction of unscheduled DNA synthesis in hairless mouse epidermis by skin carcinogens.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens; Cocarcinogenesis; DNA; DNA Damage; Dose-Response Relationship, Drug; Epoxy Compounds; Female; Hydroxyurea; Methylnitronitrosoguanidine; Mice; Mice, Hairless; Quinolones; Skin | 1999 |
Inhibition of aryl hydrocarbon-induced cytochrome P-450 1A1 enzyme activity and CYP1A1 expression by resveratrol.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Anticarcinogenic Agents; Benzo(a)pyrene; Carcinogens; Cytochrome P-450 CYP1A1; Enzyme Activation; Enzyme Inhibitors; Gene Expression; Humans; Receptors, Aryl Hydrocarbon; Resveratrol; Stilbenes; Tumor Cells, Cultured | 1999 |
Modulation of chemical carcinogen-induced unscheduled DNA synthesis by dehydroepiandrosterone (DHEA) in the primary rat hepatocytes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens; Dehydroepiandrosterone; DNA; Ethyl Methanesulfonate; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Male; Methyl Methanesulfonate; Rats; Rats, Sprague-Dawley | 1999 |
Formation of stable DNA adducts and apurinic sites upon metabolic activation of bay and fjord region polycyclic aromatic hydrocarbons in human cell cultures.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apurinic Acid; Bay-Region, Polycyclic Aromatic Hydrocarbon; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Carcinogens; Cytochrome P-450 Enzyme System; DNA Adducts; DNA, Neoplasm; Dose-Response Relationship, Drug; HL-60 Cells; Humans; Peroxidases; Polycyclic Aromatic Hydrocarbons; Structure-Activity Relationship; Tumor Cells, Cultured | 2000 |
Protein tyrosine kinase activation by polycyclic aromatic hydrocarbons in human HPB-ALL T cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Analysis of Variance; Anthracenes; Benzo(a)pyrene; Benzopyrenes; Carcinogens, Environmental; Cell Line; Humans; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Lymphocytes; Polycyclic Aromatic Hydrocarbons; Structure-Activity Relationship | 1999 |
In vitro detection of indirect-acting genotoxins in the comet assay using Hep G2 cells.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Benzo(a)pyrene; Biotransformation; Carcinogens; Carcinoma, Hepatocellular; Comet Assay; Cyclophosphamide; DNA Damage; DNA, Neoplasm; Humans; Image Processing, Computer-Assisted; Liver Neoplasms; Mutagens; Prodrugs; Sensitivity and Specificity; Tumor Cells, Cultured | 2000 |
Ovotoxicity in female Fischer rats and B6 mice induced by low-dose exposure to three polycyclic aromatic hydrocarbons: comparison through calculation of an ovotoxic index.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Body Weight; Cyclohexanes; Cyclohexenes; Dose-Response Relationship, Drug; Female; Liver; Methylcholanthrene; Mice; Mice, Inbred Strains; Organ Size; Ovarian Follicle; Rats; Rats, Inbred F344; Species Specificity; Vinyl Compounds | 2000 |
Oral administration of naturally occurring coumarins leads to altered phase I and II enzyme activities and reduced DNA adduct formation by polycyclic aromatic hydrocarbons in various tissues of SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Carcinogens; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA Adducts; Female; Furocoumarins; Glutathione Transferase; Liver; Lung; Mammary Glands, Animal; Mice; Mice, Inbred SENCAR; Skin; Stomach | 2001 |
Manganese inhibition of sarcoma induction by benzo[a]pyrene in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Carcinogens; Chromium; Drug Interactions; Dust; Injections, Intramuscular; Male; Manganese; Rats; Rats, Inbred F344; Sarcoma, Experimental | 1980 |
Induction of sister chromatid exchanges by carcinogens mediated through cultured rat liver epithelial cells.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Animals; Antimetabolites; Benzo(a)pyrene; Bromodeoxyuridine; Carcinogenicity Tests; Carcinogens; Cell Line; CHO Cells; Coculture Techniques; Cricetinae; Epithelial Cells; Liver; Male; Mycotoxins; Rats; Rats, Inbred Lew; Sister Chromatid Exchange | 1980 |
Cancer chemopreventive activities of S-3-1, a synthetic derivative of danshinone.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Benzofurans; Bepridil; Biphenyl Compounds; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Croton Oil; Cysteine; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Epithelial Cells; Fibroblasts; Free Radical Scavengers; Hypoxanthine; In Vitro Techniques; Iron; Lipid Peroxidation; Lung; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred ICR; Microsomes, Liver; Molecular Structure; Mutagens; Ornithine; Ornithine Decarboxylase; Papilloma; Pentetic Acid; Phenanthrenes; Picrates; Plants, Medicinal; Rats; Salmonella; Skin; Skin Neoplasms; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Xanthine Oxidase | 2001 |
Tumourigenic studies on deltamethrin in Swiss albino mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Benzo(a)pyrene; Carcinogenicity Tests; Carcinogens; Cocarcinogenesis; Female; Insecticides; Male; Mice; Nitriles; Pyrethrins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2001 |
Modulation of glucose-6-phosphate dehydrogenase activity and expression is associated with aryl hydrocarbon resistance in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Benzo(a)pyrene; Carcinogens; Gene Expression Regulation, Enzymologic; Glucosephosphate Dehydrogenase; Glutathione; Humans; Inactivation, Metabolic; Promoter Regions, Genetic; RNA, Messenger; Tumor Cells, Cultured | 2001 |
Immunosuppression and carcinogenesis: contrasting effects with 7,12-dimethylbenz[a]anthracene, benz[a]pyrene, and 3-methylcholanthrene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Antibody Formation; Benzo(a)pyrene; Carcinogens; Immunosuppressive Agents; Lymphoma; Methylcholanthrene; Mice; Thymus Neoplasms; Time Factors | 1970 |
Relationship of selenium to cancer. I. Inhibitory effect of selenium on carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Antioxidants; Benzo(a)pyrene; Carcinogens; Croton Oil; Female; Mice; Mice, Inbred ICR; Papilloma; Selenium; Skin Neoplasms; Vitamin E | 1970 |
Further evaluation of an in vivo micronucleus test on rat and mouse skin: results with five skin carcinogens.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens; Male; Methylnitronitrosoguanidine; Mice; Mice, Inbred ICR; Micronucleus Tests; Rats; Rats, Sprague-Dawley; Skin | 2002 |
Chemomodulation of carcinogen metabolising enzymes, antioxidant profiles and skin and forestomach papillomagenesis by Spirulina platensis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Benzo(a)pyrene; Body Weight; Carcinogens; Catalase; Cyanobacteria; Cytochrome Reductases; Cytochrome-B(5) Reductase; Cytosol; Gastric Mucosa; Glutathione; Glutathione Reductase; Glutathione Transferase; L-Lactate Dehydrogenase; Lipid Metabolism; Lipid Peroxidation; Liver; Mice; Microsomes, Liver; NAD(P)H Dehydrogenase (Quinone); NADPH-Ferrihemoprotein Reductase; Neoplasm Transplantation; Organ Size; Oxidation-Reduction; Papilloma; Skin; Skin Neoplasms; Superoxide Dismutase; Time Factors | 2001 |
The Liverbeads as a tool for the comet assay.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Aged; Animals; Benzo(a)pyrene; Biotransformation; Carcinogens; Comet Assay; Cyclophosphamide; DNA Damage; DNA, Neoplasm; Female; HeLa Cells; Hepatocytes; Humans; Liver; Male; Microspheres; Middle Aged; Mutagens; Prodrugs; Rats; Sensitivity and Specificity | 2002 |
Dioxin stimulates RANTES expression in an in-vitro model of endometriosis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Benzo(a)pyrene; Cells, Cultured; Chemokine CCL5; Dioxins; Endometriosis; Endometrium; Female; Gene Expression; Humans; NF-kappa B; Polychlorinated Dibenzodioxins; Promoter Regions, Genetic; Receptors, Aryl Hydrocarbon; Response Elements; Stromal Cells; Transfection; Tumor Necrosis Factor-alpha | 2002 |
Uptake rate measurement of some amino acids on normal and treated yeast cells to xenobiotics using 14C labelled amino acid.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acids; Benzo(a)pyrene; Biological Transport; Carbon Radioisotopes; Carcinogens; Kinetics; Saccharomyces cerevisiae; Scintillation Counting; Xenobiotics | 2002 |
Modulating effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on skin carcinogenesis initiated by the weak inducer 7,12-dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Buffers; Carcinogens; Cytosol; DNA; Environmental Pollutants; Enzyme Induction; Mice; Mice, Inbred C57BL; Microsomes; Polychlorinated Dibenzodioxins; Polycyclic Aromatic Hydrocarbons; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon; Skin; Skin Neoplasms | 1994 |
[Effect of 5 polycyclic aromatic hydrocarbons on estrogen receptor binding in rats].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Anthracenes; Benzo(a)pyrene; Binding Sites; Chrysenes; Female; Polycyclic Aromatic Hydrocarbons; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Uterus | 2002 |
Naturally occurring coumarins inhibit human cytochromes P450 and block benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene DNA adduct formation in MCF-7 cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Antineoplastic Agents; Benzo(a)pyrene; Breast Neoplasms; Carcinogens; Coumarins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA; DNA Adducts; Furocoumarins; Humans; Inhibitory Concentration 50; Isoenzymes; Tumor Cells, Cultured | 2003 |
[Effect of ultraviolet rays on 9,10-dimethyl-1,2-benzanthracene- & 3,4-benzopyrene-induced skin carcinogenesis in the rat].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthracenes; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Carcinogenesis; Neoplasms, Experimental; Rats; Skin Neoplasms; Ultraviolet Rays | 1959 |
Bone marrow cytotoxicity of benzo[a]pyrene is dependent on CYP1B1 but is diminished by Ah receptor-mediated induction of CYP1A1 in liver.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Blotting, Western; Bone Marrow Cells; Carcinogens; Cell Count; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Enzyme Induction; Female; Flow Cytometry; In Situ Hybridization; Liver; Male; Mice; Mice, Inbred C57BL; Receptors, Aryl Hydrocarbon; Reverse Transcriptase Polymerase Chain Reaction; RNA | 2003 |
Availability of specific reductases controls the temporal activity of the cytochrome P450 complement of Streptomyces coelicolor A3(2).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Benzo(a)pyrene; Cytochrome P-450 Enzyme System; Gene Expression Regulation, Enzymologic; Oxidoreductases; Reverse Transcriptase Polymerase Chain Reaction; Streptomyces | 2004 |
Modulation of carcinogen metabolism and DNA interaction by calcium glucarate in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Carcinogens; Cattle; DNA; Dose-Response Relationship, Drug; Drug Administration Schedule; Glucaric Acid; Mice; Microsomes; Skin; Thymidine Kinase; Thymus Gland; Time Factors; Tritium | 2004 |
Synthesis of the o-quinones and other oxidized metabolites of polycyclic aromatic hydrocarbons implicated in carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Benz(a)Anthracenes; Benzo(a)pyrene; Carcinogens; Catechols; Epoxy Compounds; Molecular Structure; Oxidation-Reduction; Polycyclic Aromatic Hydrocarbons; Quinones; Stereoisomerism | 2004 |
Chemomodulatory efficacy of basil leaf (Ocimum basilicum) on drug metabolizing and antioxidant enzymes, and on carcinogen-induced skin and forestomach papillomagenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Catalase; Glutathione Reductase; Kidney; Lipid Peroxidation; Liver; Lung; Mice; Ocimum basilicum; Phytotherapy; Plant Extracts; Plant Leaves; Skin Neoplasms; Stomach; Stomach Neoplasms; Superoxide Dismutase | 2004 |
Chemopreventive potential of Azadirachta indica (Neem) leaf extract in murine carcinogenesis model systems.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Anticarcinogenic Agents; Antioxidants; Azadirachta; Benzo(a)pyrene; Disease Models, Animal; Dose-Response Relationship, Drug; Lipid Peroxidation; Liver; Mice; Phytotherapy; Plant Extracts; Plant Leaves; Skin Neoplasms; Stomach Neoplasms | 2004 |
Alteration in phase I and II enzyme activities and polycyclic aromatic hydrocarbons-DNA adduct formation by plant phenolics in mouse epidermis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Anticarcinogenic Agents; Antimutagenic Agents; Benzo(a)pyrene; DNA Adducts; Dose-Response Relationship, Drug; Epidermis; Female; Hydroxybenzoates; Mice; Polycyclic Aromatic Hydrocarbons; Resveratrol; Stilbenes | 2004 |
The mutagenic effects of 7,12-dimethylbenz[a]anthacene, 3-methylcholanthrene and benzo[a]pyrene to the developing Syrian hamster fetus measured by an in vivo/in vitro mutation assay.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Cricetinae; Fetus; Mesocricetus; Methylcholanthrene; Mutagens; Mutation | 2004 |
Induction of CYP1A1 and CYP1B1 in liver and lung by benzo(a)pyrene and 7,12-d imethylbenz(a)anthracene do not affect distribution of polycyclic hydrocarbons to target tissue: role of AhR and CYP1B1 in bone marrow cytotoxicity.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Bone Marrow Cells; Carcinogens, Environmental; Cells, Cultured; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; DNA Adducts; Enzyme Induction; In Situ Hybridization; Liver; Lung; Male; Mice; Mice, Inbred C57BL; Polycyclic Compounds; Receptors, Aryl Hydrocarbon; RNA, Messenger; Tissue Distribution | 2005 |
Benzo(a)pyrene and 7,12-dimethylbenz(a)anthrecene differentially affect bone marrow cells of the lymphoid and myeloid lineages.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Bone Marrow Cells; Cell Count; Cell Lineage; Cytochrome P-450 CYP1B1; Environmental Pollutants; Female; Immunosuppression Therapy; Lymphocyte Subsets; Lymphocytes; Male; Mice; Mice, Inbred C57BL; Myeloid Cells; Myeloid Progenitor Cells; Polycyclic Aromatic Hydrocarbons; Random Allocation; RNA, Messenger; Tumor Necrosis Factor-alpha | 2006 |
Nine-week detection of six genotoxic lung carcinogens using the rasH2/BHT mouse model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkylating Agents; Animals; Antioxidants; Benzo(a)pyrene; Butylated Hydroxytoluene; Carcinogenicity Tests; Carcinogens; Diethylnitrosamine; Dimethylnitrosamine; Disease Models, Animal; Ethylnitrosourea; Female; Humans; Incidence; Lung Neoplasms; Male; Methylcholanthrene; Mice; Mice, Transgenic; Oncogene Protein p21(ras) | 2006 |
In vitro anti-mutagenic effect of magnolol against direct and indirect mutagens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthracenes; Antimutagenic Agents; Benzo(a)pyrene; Biphenyl Compounds; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Imidazoles; Kinetics; Lignans; Male; Methylnitronitrosoguanidine; Microsomes, Liver; Molecular Structure; Mutagenicity Tests; Mutagens; Oxidoreductases; Quinoxalines; Rats; Rats, Sprague-Dawley; Salmonella typhimurium | 2006 |
Deleterious effects of polynuclear aromatic hydrocarbon on blood vascular system of the rat fetus.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Blood Vessels; Female; Fetal Development; Fetal Growth Retardation; Gestational Age; Hemorrhage; Placenta; Polycyclic Aromatic Hydrocarbons; Pregnancy; Rats; Rats, Sprague-Dawley | 2007 |
The effect of initiating doses of benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene on the expression of PAH activating enzymes and its modulation by plant phenols.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens, Environmental; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Epidermis; Female; Metabolic Detoxication, Phase II; Mice; Mice, Inbred BALB C; Phenols; Plant Preparations | 2008 |
Cyp1b1 exerts opposing effects on intestinal tumorigenesis via exogenous and endogenous substrates.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; beta Catenin; Carcinogens; Cytochrome P-450 CYP1B1; Female; I-kappa B Kinase; Intestinal Neoplasms; Male; Mice; Mice, Inbred C57BL; Olive Oil; Phosphorylation; Plant Oils; Transcription Factor RelA | 2008 |
The zebrafish gill model: induction of CYP1A, EROD and PAH adduct formation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Gene Expression Regulation; Gills; Liver; Polycyclic Aromatic Hydrocarbons; Zebrafish | 2009 |
Pig-a mutation: kinetics in rat erythrocytes following exposure to five prototypical mutagens.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Erythrocytes; Ethylnitrosourea; Membrane Proteins; Methylnitrosourea; Mutagenicity Tests; Mutagens; Mutation; Rats; Rats, Sprague-Dawley; Rats, Wistar | 2010 |
Chemomodulatory effect of Trachyspermum ammi on murine skin and forestomach papillomagenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antioxidants; Apiaceae; Benzo(a)pyrene; Carcinogens; Cytochrome P-450 Enzyme System; Diet; Female; Glutathione Transferase; L-Lactate Dehydrogenase; Liver; Mice; NAD(P)H Dehydrogenase (Quinone); Papilloma; Seeds; Skin Neoplasms; Stomach Neoplasms | 2010 |
Expression of CYP1C1 and CYP1A in Fundulus heteroclitus during PAH-induced carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Dimethyl Sulfoxide; Fish Diseases; Fundulidae; Immunohistochemistry; Intestinal Mucosa; Kidney Tubules; Liver Neoplasms; Time Factors | 2010 |
Use of the human monocytic leukemia THP-1 cell line and co-incubation with microsomes to identify and differentiate hapten and prohapten sensitizers.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Cell Line, Tumor; Dose-Response Relationship, Drug; Eugenol; Haptens; Humans; Microsomes, Liver; Monocytes; Propanols; Rats | 2011 |
[Interaction of mutagens in binary mixtures using the alkaline comet assay in human lymphocytes].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult; Benzo(a)pyrene; Biotransformation; Carbolines; Cell Survival; Cells, Cultured; Comet Assay; DNA Damage; Drug Interactions; Furans; Humans; In Vitro Techniques; Inhibitory Concentration 50; Lymphocytes; Male; Microsomes, Liver; Mutagens | 2012 |
Establishment of a new OSCC cell line derived from OLK and identification of malignant transformation-related proteins by differential proteomics approach.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Apoptosis; Benzo(a)pyrene; Biomarkers, Tumor; Carcinogens; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Gene Expression Regulation; Humans; Leukoplakia, Oral; Mouth Neoplasms; Neoplasm Proteins; Proteomics | 2015 |
Methylnitrosourea, dimethylbenzanthracene and benzoapyrene differentially affect redox pathways, apoptosis and immunity in zebrafish.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Apoptosis Regulatory Proteins; Benzo(a)pyrene; Carcinogens; Embryo, Nonmammalian; Glutathione Transferase; Interferon-gamma; Methylnitrosourea; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Superoxide Dismutase; Zebrafish; Zebrafish Proteins | 2020 |