Page last updated: 2024-08-17

9,10-dimethyl-1,2-benzanthracene and ascorbic acid

9,10-dimethyl-1,2-benzanthracene has been researched along with ascorbic acid in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199016 (44.44)18.7374
1990's7 (19.44)18.2507
2000's8 (22.22)29.6817
2010's3 (8.33)24.3611
2020's2 (5.56)2.80

Authors

AuthorsStudies
Burden, PM; Grover, PL; Hewer, A; Macnicoll, AD; Ribeiro, O; Sims, P1
Bracken, WM; Slaga, TJ1
Cleveland, S; Jellinck, PH; Smith, G1
Kandarkar, SV; Potdar, PD; Sirsat, SM1
Hussain, SP; Jannu, LN; Ramesha, A; Rao, AR; Rao, N1
Bodo, M; Guerrieri, P; Liotti, FS; Menghini, AR; Pezzetti, F1
Ip, C2
Fukushima, S; Hirose, M; Inoue, T; Ito, N; Masuda, A1
Welsch, CW1
Dixit, A; Rao, R1
Arai, T; Endo, K; Hirai, T; Iino, Y; Ishikawa, H; Izuo, M; Kawai, T; Ogawa, T; Takikawa, H; Yamazaki, K1
Arai, T; Endo, K; Hoshino, K; Iino, Y; Ishida, T; Ishikawa, H; Ogawa, T; Takahashi, T; Yamazaki, K; Yokoe, T1
Dixit, A; Rao, AR1
Bigger, CA; Blake, DM; Dipple, A; Pigott, MA1
Shoyab, M1
Abdelmegid, N; Sadek, IA1
Abul-Hajj, YJ; Kelliher, M1
Cheverie, SR; Schwartz, J; Shklar, G; Trickler, D1
Schwartz, J; Shklar, G; Trickler, D1
Futakuchi, M; Hirose, M; Miki, T; Ozaki, M; Shirai, T; Tanaka, H1
Agarwal, R; Chen, Y; Wang, J; Zhao, J1
Kandarkar, SV; Sawant, SS1
Aidoo, A; Bishop, ME; Chen, JJ; Desai, VG; Khaidakov, M; Lyn-Cook, LE; Manjanatha, MG1
Aidoo, A; Casciano, D; Desai, VG; Feuers, RJ1
McCann, RA; Mitchel, RE1
el-Aaser, AA; el-Guindy, SM; Hafiez, AR; Halawa, F; Mokhtar, N; Zakhary, NI1
Chodon, D; Padmavathi, R; Sakthisekaran, D; Senthilnathan, P1
Arunakaran, J; Balasubramanian, K; Govindarajulu, P; Rajkumar, L; Srinivasan, N1
Arulkumaran, S; Ramprasath, VR; Sachdanandam, P; Shanthi, P1
Ivanov, V; Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW; Roomi, NW1
Goyal, PK; Parmar, J; Sharma, P; Verma, P1
Krishnaveni, M; Mirunalini, S1
Berber, I; Ekin, S; Levent, A; Oto, G1
Adeleye, OO; Akamo, AJ; Dosumu, OA; Omotosho, OO; Osinuga, KT; Rotimi, SO; Sani, LO; Taiwo, OA1
Samuel Metibemu, D1

Reviews

1 review(s) available for 9,10-dimethyl-1,2-benzanthracene and ascorbic acid

ArticleYear
Host factors affecting the growth of carcinogen-induced rat mammary carcinomas: a review and tribute to Charles Brenton Huggins.
    Cancer research, 1985, Volume: 45, Issue:8

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Cortex Hormones; Animals; Antioxidants; Ascorbic Acid; Castration; Cocarcinogenesis; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Gonadal Steroid Hormones; Insulin; Male; Mammary Neoplasms, Experimental; Methylcholanthrene; Methylnitrosourea; Neoplasm Transplantation; Nucleotides, Cyclic; Pituitary Hormones, Anterior; Prostaglandins; Rats; Retinoids; Selenium; Thyroid Hormones; Vitamin E

1985

Other Studies

35 other study(ies) available for 9,10-dimethyl-1,2-benzanthracene and ascorbic acid

ArticleYear
The formation of dihydrodiols by the chemical or enzymic oxidation of 7-hydroxymethyl-12-methylbenz[alpha]anthracene and the possible role of hydroxymethyl dihydrodiols in the metabolic activation of 7,12-dimethylbenz[alpha]anthracene.
    Chemico-biological interactions, 1979, Volume: 26, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Ascorbic Acid; Benz(a)Anthracenes; Biotransformation; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Chromatography, Thin Layer; Culture Techniques; DNA; Edetic Acid; Ferrous Compounds; Male; Mice; Microsomes, Liver; Oxidation-Reduction; Rats; Skin; Sulfates

1979
The effects of antioxidants on skin tumor initiation and aryl hydrocarbon hydroxylase.
    Cancer research, 1977, Volume: 37, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Antioxidants; Aryl Hydrocarbon Hydroxylases; Ascorbic Acid; Benz(a)Anthracenes; Benzopyrenes; Butylated Hydroxyanisole; Butylated Hydroxytoluene; DNA; Enzyme Induction; Female; Flavonoids; In Vitro Techniques; Mice; Neoplasms, Experimental; Skin; Skin Neoplasms; Vitamin E

1977
Metabolism of (4-14C)estradiol by 7,12-dimethylbenz(a) anthracene-induced mammary tumor peroxidase.
    Steroids, 1975, Volume: 26, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Amitrole; Animals; Ascorbic Acid; Azides; Benz(a)Anthracenes; Catalase; Cyanides; Estradiol; Ethylmaleimide; Female; Iodoacetamide; Kinetics; Lactoperoxidase; Mammary Neoplasms, Experimental; Peroxidases; Rats

1975
Modulation by vitamin C of tumour incidence and inhibition in oral carcinogenesis.
    Functional and developmental morphology, 1992, Volume: 2, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Ascorbic Acid; Cricetinae; Incidence; Male; Mesocricetus; Mouth Neoplasms

1992
Chemoprevention of 7,12-dimethylbenz[a]anthracene-induced mammary carcinogenesis in rat by the combined actions of selenium, magnesium, ascorbic acid and retinyl acetate.
    Japanese journal of cancer research : Gann, 1990, Volume: 81, Issue:12

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Animals; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Body Weight; Diterpenes; Drug Administration Schedule; Female; Magnesium Chloride; Mammary Neoplasms, Experimental; Rats; Retinyl Esters; Selenic Acid; Selenium; Selenium Compounds; Vitamin A

1990
Inhibition of the binding of 7,12-dimethylbenz[a]anthracene to DNA by ascorbic acid, reduced glutathione and cysteine in chick embryo cells cultured in vitro.
    Oncology, 1986, Volume: 43, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Ascorbic Acid; Cells, Cultured; Chick Embryo; Cysteine; DNA; Glutathione

1986
Selenium and experimental cancer.
    Annals of clinical research, 1986, Volume: 18, Issue:1

    Topics: 1,2-Dimethylhydrazine; 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Animals; Ascorbic Acid; Cricetinae; Diet; Dimethylhydrazines; DNA; Drug Interactions; Mammary Neoplasms, Experimental; Mice; Neoplasms, Experimental; Rats; Selenium; Vitamin A; Vitamin E

1986
Modification by antioxidants and p,p'-diaminodiphenylmethane of 7,12-dimethylbenz[a]anthracene-induced carcinogenesis of the mammary gland and ear duct in CD rats.
    Carcinogenesis, 1986, Volume: 7, Issue:7

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Ascorbic Acid; Bisacodyl; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Cell Transformation, Neoplastic; Cresols; Diet; Ear Neoplasms; Ethoxyquin; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Vitamin E

1986
Interaction of vitamin C and selenium supplementation in the modification of mammary carcinogenesis in rats.
    Journal of the National Cancer Institute, 1986, Volume: 77, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Ascorbic Acid; Dose-Response Relationship, Drug; Drug Interactions; Female; Liver; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Selenious Acid; Selenium; Selenomethionine

1986
Influence of ascorbic acid on action of DMBA on DNA, RNA & protein levels in mouse liver following partial hepatectomy.
    Indian journal of experimental biology, 1980, Volume: 18, Issue:12

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Ascorbic Acid; Benz(a)Anthracenes; DNA; Female; Hepatectomy; Liver; Mice; Protein Biosynthesis; RNA

1980
[Effect of medroxyprogesterone acetate (MAP) and vitamin C on DMBA induced rat mammary cancer in relation to estrogen receptor(ER)].
    Gan no rinsho. Japan journal of cancer clinics, 1983, Volume: 29, Issue:9

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Ascorbic Acid; Female; Male; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Nandrolone; Rats; Rats, Inbred Strains; Receptors, Estrogen

1983
[Changes of hormone receptor status in various treatment for human breast cancer and DMBA tumor of the rat].
    Gan no rinsho. Japan journal of cancer clinics, 1984, Volume: 30, Issue:13

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Middle Aged; Rats; Receptors, Estrogen; Receptors, Progesterone

1984
Effect of ascorbic acid & DMBA on lysosomal enzymes' activity in partially hepatectomized mouse liver.
    Indian journal of experimental biology, 1983, Volume: 21, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Ascorbic Acid; Benz(a)Anthracenes; Hydrolases; Liver; Liver Regeneration; Lysosomes; Mice

1983
7,12-dimethylbenz[a] anthracene--DNA binding in mouse skin: response of different mouse strains and effects of various modifiers of carcinogenesis.
    Carcinogenesis, 1984, Volume: 5, Issue:8

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Ascorbic Acid; Benz(a)Anthracenes; Benzoflavones; Butylated Hydroxyanisole; Butylated Hydroxytoluene; DNA; Female; Male; Mice; Mice, Inbred C57BL; Skin; Species Specificity; Vitamin E

1984
Inhibition of the binding of 7,12-dimethylbenz [alpha] anthracene to DNA of murine epidermal cells in culture by vitamin A and vitamin C.
    Oncology, 1981, Volume: 38, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Ascorbic Acid; Benz(a)Anthracenes; Cells, Cultured; DNA; Epidermis; Mice; Vitamin A

1981
Ascorbic acid and its effect on the skin of Bufo regularis.
    Oncology, 1982, Volume: 39, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Ascorbic Acid; Bufonidae; Female; Male; Neoplasms, Experimental; Papilloma; Skin Neoplasms

1982
Failure of ascorbic acid to inhibit growth of transplantable and dimethylbenzanthracene induced rat mammary tumors.
    Cancer letters, 1982, Volume: 17, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Ascorbic Acid; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains

1982
The effectiveness of a mixture of beta-carotene, alpha-tocopherol, glutathione, and ascorbic acid for cancer prevention.
    Nutrition and cancer, 1993, Volume: 20, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Ascorbic Acid; beta Carotene; Carotenoids; Cricetinae; Drug Combinations; Drug Synergism; Glutathione; Leukoplakia; Male; Mesocricetus; Mouth Neoplasms; Vitamin E

1993
Vitamin C enhances the development of carcinomas in the hamster buccal pouch experimental model.
    Oral surgery, oral medicine, and oral pathology, 1993, Volume: 76, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Ascorbic Acid; Carcinogens; Carcinoma, Squamous Cell; Cheek; Cocarcinogenesis; Cricetinae; Drug Synergism; Leukoplakia, Oral; Male; Mesocricetus; Mouth Neoplasms

1993
Inhibition of DMBA-initiated rat mammary tumour development by 1-O-hexyl-2,3,5-trimethylhydroquinone, phenylethyl isothiocyanate, and novel synthetic ascorbic acid derivatives.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 1998, Volume: 7, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Anticarcinogenic Agents; Antioxidants; Ascorbic Acid; Carcinogens; Cell Transformation, Neoplastic; Chemoprevention; Diet; Female; Hydroquinones; Isothiocyanates; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley

1998
Anti-tumor-promoting activity of a polyphenolic fraction isolated from grape seeds in the mouse skin two-stage initiation-promotion protocol and identification of procyanidin B5-3'-gallate as the most effective antioxidant constituent.
    Carcinogenesis, 1999, Volume: 20, Issue:9

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Administration, Cutaneous; Animals; Anticarcinogenic Agents; Antioxidants; Ascorbic Acid; Biflavonoids; Catechin; Cocarcinogenesis; Epidermis; Female; Flavonoids; Lipid Peroxidation; Mice; Mice, Inbred SENCAR; Microsomes; Molecular Structure; Phenols; Plant Extracts; Polymers; Proanthocyanidins; Rosales; Seeds; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vitamin E

1999
Role of vitamins C and E as chemopreventive agents in the hamster cheek pouch treated with the oral carcinogen-DMBA.
    Oral diseases, 2000, Volume: 6, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antioxidants; Ascorbic Acid; Basement Membrane; Carcinogens; Carcinoma, Squamous Cell; Cheek; Chemoprevention; Chi-Square Distribution; Cricetinae; Cytoplasm; Drug Combinations; Epithelium; Hemidesmosomes; Leukoplakia, Oral; Male; Mesocricetus; Mitosis; Mouth Mucosa; Mouth Neoplasms; Papilloma; Parakeratosis; Vitamin E

2000
Influence of dietary antioxidants on the mutagenicity of 7,12-dimethylbenz[a]anthracene and bleomycin in female rats.
    Mutation research, 2001, Sep-01, Volume: 480-481

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Antioxidants; Ascorbic Acid; beta Carotene; Bleomycin; Cells, Cultured; Clone Cells; Dietary Supplements; DNA Mutational Analysis; Drug Administration Schedule; Female; Hypoxanthine Phosphoribosyltransferase; Lymphocytes; Mutagenicity Tests; Mutation; Rats; Rats, Inbred F344; Selenium; Spleen; Vitamin E

2001
Activity profile of glutathione-dependent enzymes and respiratory chain complexes in rats supplemented with antioxidants and treated with carcinogens.
    Archives of biochemistry and biophysics, 2001, Oct-15, Volume: 394, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Ascorbic Acid; beta Carotene; Bleomycin; Carcinogens; Dietary Supplements; Drug Administration Schedule; Electron Transport; Electron Transport Complex I; Electron Transport Complex II; Electron Transport Complex III; Electron Transport Complex IV; Enzyme Activation; Female; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Liver; Mitochondria, Liver; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Oxidoreductases; Rats; Rats, Inbred F344; Selenium; Succinate Dehydrogenase; Vitamin E

2001
Skin tumor promotion by Vitamin E in mice: amplification by ionizing radiation and Vitamin C.
    Cancer detection and prevention, 2003, Volume: 27, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Antioxidants; Ascorbic Acid; Beta Particles; Carcinogens; Cocarcinogenesis; Female; Free Radical Scavengers; Mice; Mice, Inbred SENCAR; Oxidation-Reduction; Radiation, Ionizing; Skin; Skin Neoplasms; Vitamin E

2003
Effect of soybean, Vicia faba, and vitamin C on the carcinogenicity of DMBA.
    Nutrition and cancer, 1994, Volume: 22, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Ascorbic Acid; Carcinoma; Dose-Response Relationship, Drug; Female; Glycine max; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats

1994
Therapeutic effect of paclitaxel and propolis on lipid peroxidation and antioxidant system in 7,12 dimethyl benz(a)anthracene-induced breast cancer in female Sprague Dawley rats.
    Life sciences, 2006, May-08, Volume: 78, Issue:24

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Ascorbic Acid; Body Weight; Carcinogens; Catalase; Female; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Mammary Neoplasms, Experimental; Paclitaxel; Propolis; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Vitamin E

2006
Influence of estradiol on mammary tumor collagen solubility in DMBA-induced rat mammary tumors.
    Cell biology international, 2006, Volume: 30, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Ascorbic Acid; Collagen; Estradiol; Female; Lactic Acid; Mammary Neoplasms, Experimental; Progesterone; Prolactin; Rats; Rats, Wistar; Solubility

2006
Alteration of DMBA-induced oxidative stress by additive action of a modified indigenous preparation--Kalpaamruthaa.
    Chemico-biological interactions, 2007, Apr-25, Volume: 167, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Ascorbic Acid; Drug Synergism; Female; Glutathione; Liver; Mammary Neoplasms, Experimental; Medicine, Ayurvedic; Mitochondria, Liver; Oxidative Stress; Phytotherapy; Plant Extracts; Random Allocation; Rats; Rats, Sprague-Dawley; Vitamin E

2007
Inhibition of 7,12-dimethylbenzanthracene-induced skin tumors by a nutrient mixture.
    Medical oncology (Northwood, London, England), 2008, Volume: 25, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetylcysteine; Amino Acids; Animals; Arginine; Ascorbic Acid; Camellia sinensis; Carcinogens; Copper; Diet; Female; Keratoacanthoma; Lysine; Manganese; Mice; Mice, Inbred SENCAR; Papilloma; Plant Extracts; Proline; Selenium; Skin; Skin Neoplasms

2008
Modulatory influence of Phyllanthus niruri on oxidative stress, antioxidant defense and chemically induced skin tumors.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2011, Volume: 30, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Ascorbic Acid; Glutathione; Lipid Peroxidation; Male; Mice; Oxidative Stress; Papilloma; Phyllanthus; Phytotherapy; Plant Extracts; Skin Neoplasms

2011
Chemopreventive efficacy of Phyllanthus emblica L. (amla) fruit extract on 7,12-dimethylbenz(a)anthracene induced oral carcinogenesis--a dose-response study.
    Environmental toxicology and pharmacology, 2012, Volume: 34, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Ascorbic Acid; Catalase; Cricetinae; Fruit; Glutathione; Glutathione Peroxidase; Male; Mouth Neoplasms; Phyllanthus emblica; Plant Extracts; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Vitamin E

2012
Method validation and simultaneous determination of retinol, retinyl palmitate, β-carotene, α-tocopherol and vitamin C in rat serum treated with 7,12 dimethylbenz[a]anthracene and Plantago major L. by high- performance liquid chromatography using diode-ar
    Combinatorial chemistry & high throughput screening, 2013, Volume: 16, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; alpha-Tocopherol; Animals; Ascorbic Acid; beta Carotene; Carcinogens; Chromatography, High Pressure Liquid; Diterpenes; Plant Extracts; Plantago; Rats; Rats, Wistar; Retinyl Esters; Sensitivity and Specificity; Vitamin A

2013
Vitamin K protects against 7,12-dimethylbenz(A)anthracene induced hepatotoxicity in Wistar rats.
    Environmental toxicology, 2021, Volume: 36, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthracenes; Antioxidants; Ascorbic Acid; Catalase; Chemical and Drug Induced Liver Injury; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Liver; Male; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Vitamin K

2021
vHTS and 3D-QSAR for the Identification of Novel Phyto-inhibitors of Farnesyltransferase: Validation of Ascorbic Acid inhibition of Farnesyltransferase in an Animal Model of Breast Cancer.
    Drug research, 2021, Volume: 71, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Anacardiaceae; Animals; Antineoplastic Agents, Phytogenic; Ascorbic Acid; Carcinogens; Curcuma; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Farnesyltranstransferase; Female; High-Throughput Screening Assays; Humans; Inhibitory Concentration 50; Mammary Neoplasms, Experimental; Molecular Docking Simulation; Quantitative Structure-Activity Relationship; Rats; Taraxacum

2021