Compounds > 9-(s)-(3-hydroxy-2-(phosphonomethoxy)propyl)adenine
Page last updated: 2024-08-25

9-(s)-(3-hydroxy-2-(phosphonomethoxy)propyl)adenine and ganciclovir

9-(s)-(3-hydroxy-2-(phosphonomethoxy)propyl)adenine has been researched along with ganciclovir in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's2 (25.00)18.2507
2000's3 (37.50)29.6817
2010's1 (12.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Bisagni, E; Boumchita, H; Huel, C; Legraverend, M; Lemaitre, M; Zerial, A1
Bronson, JJ; Ghazzouli, I; Hitchcock, MJ; Martin, JC; Webb, RR1
Andrei, G; Balzarini, J; Claes, P; De Clercq, E; Rozenski, J; Snoeck, R; Van Aerschot, A; Van Meervelt, L; Verheggen, I; Wiebe, L1
Andrei, G; Balzarini, J; Camarasa, MJ; de Castro, S; Naesens, L; Peromingo, MT; Snoeck, R; Velázquez, S1
Chou, KC; González-Díaz, H; Martinez de la Vega, O; Prado-Prado, FJ; Ubeira, FM; Uriarte, E1
Andrei, G; Balzarini, J; Camarasa, MJ; De Castro, S; García-Aparicio, C; Snoeck, R; Velázquez, S1
Borysko, KZ; Breitenbach, JM; Collins, M; Drach, JC; Hilfinger, JM; Kashemirov, BA; Krylov, IS; McKenna, CE; Peterson, LW; Serpi, M; Zakharova, VM1
Groaz, E; Herdewijn, P; Kalkeri, R; Prichard, MN; Ptak, R; Tan, S1

Other Studies

8 other study(ies) available for 9-(s)-(3-hydroxy-2-(phosphonomethoxy)propyl)adenine and ganciclovir

ArticleYear
Synthesis of new (+-)-3,5-dihydroxypentyl nucleoside analogues from 1-amino-5-(benzyloxy)pentan-3-ol and their antiviral evaluation.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:9

    Topics: Amino Alcohols; Antiviral Agents; Cell Line; Chemical Phenomena; Chemistry; Humans; Microbial Sensitivity Tests; Nucleosides; Pentanols; Structure-Activity Relationship

1990
Synthesis and antiviral activity of the nucleotide analogue (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:7

    Topics: Animals; Antiviral Agents; Chemical Phenomena; Chemistry; Cidofovir; Cytomegalovirus; Cytosine; Cytosine Nucleotides; Female; Guinea Pigs; Humans; Mice; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Vero Cells

1989
Synthesis, biological evaluation, and structure analysis of a series of new 1,5-anhydrohexitol nucleosides.
    Journal of medicinal chemistry, 1995, Mar-03, Volume: 38, Issue:5

    Topics: Animals; Antiviral Agents; Biological Transport; Cells, Cultured; Crystallography, X-Ray; Cytopathogenic Effect, Viral; Herpesviridae; Humans; Male; Mice; Models, Molecular; Molecular Conformation; Nucleosides; RNA Viruses; Structure-Activity Relationship; Sugar Alcohols

1995
4"-Benzoylureido-TSAO derivatives as potent and selective non-nucleoside HCMV inhibitors. Structure-activity relationship and mechanism of antiviral action.
    Journal of medicinal chemistry, 2008, Sep-25, Volume: 51, Issue:18

    Topics: Antiviral Agents; Cell Line; Cytomegalovirus; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Thymidine; Urea

2008
Unified QSAR approach to antimicrobials. 4. Multi-target QSAR modeling and comparative multi-distance study of the giant components of antiviral drug-drug complex networks.
    Bioorganic & medicinal chemistry, 2009, Jan-15, Volume: 17, Issue:2

    Topics: Anti-Infective Agents; Antiviral Agents; Artificial Intelligence; Computer Simulation; Drug Evaluation, Preclinical; Molecular Structure; Quantitative Structure-Activity Relationship

2009
4-Benzyloxy-gamma-sultone derivatives: discovery of a novel family of non-nucleoside inhibitors of human cytomegalovirus and varicella zoster virus.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Cytomegalovirus; Herpesvirus 3, Human; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Naphthalenesulfonates; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Virus Replication

2009
Tyrosine-based 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine and -adenine ((S)-HPMPC and (S)-HPMPA) prodrugs: synthesis, stability, antiviral activity, and in vivo transport studies.
    Journal of medicinal chemistry, 2011, Aug-25, Volume: 54, Issue:16

    Topics: Adenine; Animals; Antiviral Agents; Area Under Curve; Biological Availability; Cell Line, Tumor; Cell Survival; Cells, Cultured; Cidofovir; Cowpox virus; Cytomegalovirus; Cytosine; Fibroblasts; Herpesvirus 1, Human; Humans; Inhibitory Concentration 50; Mice; Models, Chemical; Molecular Structure; Organophosphonates; Prodrugs; Rats; Tyrosine; Vaccinia virus

2011
Introduction of a cyano group at the 2-position of an (
    RSC medicinal chemistry, 2021, May-26, Volume: 12, Issue:5

    Topics:

2021