9-(2-hydroxy-3-nonyl)adenine has been researched along with pentostatin in 38 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (57.89) | 18.7374 |
| 1990's | 10 (26.32) | 18.2507 |
| 2000's | 4 (10.53) | 29.6817 |
| 2010's | 1 (2.63) | 24.3611 |
| 2020's | 1 (2.63) | 2.80 |
| Authors | Studies |
|---|---|
| Abushanab, E; Harriman, GC; Midgett, RM; Poirot, AF; Stoeckler, JD | 1 |
| Abushanab, E; Bastian, G; Bessodes, M; Chen, SF; Panzica, RP; Parks, RE; Stoeckler, JD | 1 |
| He, Y; Hou, R; Hou, S; Liao, C; Xie, Z; Yan, G | 1 |
| Antonini, I; Cristalli, G; Franchetti, P; Grifantini, M; Lupidi, G; Martelli, S; Riva, F | 1 |
| Baker, DC; Woo, PW | 1 |
| Camaioni, E; Cristalli, G; Eleuteri, A; Lupidi, G; Vittori, S; Volpini, R | 1 |
| Hosmane, RS; Wang, L | 1 |
| Eikyu, Y; Kinoshita, T; Kuno, M; Nakamura, K; Nakanishi, I; Nishio, N; Sakane, K; Sato, A; Seki, N; Terasaka, T | 1 |
| Delaney, SM; Geiger, JD; Nagy, JI; Padua, RA | 1 |
| Corvese, D; Weitberg, AB | 1 |
| Bonnafous, JC; Clofent, G; Dornand, J; Favero, J; Mani, JC | 1 |
| Frederiksen, S; Overgaard-Hansen, K; Svendsen, KR | 1 |
| Coleman, MS; Danton, MJ | 1 |
| Kontinen, VP; Pispa, JP | 1 |
| DeLong, RE; Phillis, JW; Towner, JK | 1 |
| Dóra, E | 1 |
| Wolberg, G; Zimmerman, TP | 1 |
| Archer, S; Chan, VL; Ho, JH; Juranka, PF | 1 |
| Hsiao, N; Lum, CT; Najarian, JS; Sutherland, DE | 1 |
| Plunkett, W | 1 |
| Seegmiller, JE | 1 |
| Davis, JI; Fishbein, WN; Strong, DM; Winkert, JW | 1 |
| Cronstein, BN; Hirschhorn, R; Kramer, SB; Weissmann, G | 1 |
| Fairbanks, LD; Goday, A; Morris, GS; Simmonds, HA | 1 |
| Fox, RM; Kefford, RF | 1 |
| Coleman, MS; Deibel, MR; Hutton, JJ | 1 |
| Aye, MT; Dunne, JV | 1 |
| Ballow, M; Pantschenko, AG | 1 |
| Hirschhorn, R; Kuritsky, L; Ratech, H; Thorbecke, GJ | 1 |
| Kulkarni, JS; Palmer, KC; Przywara, DA; Wakade, AR; Wakade, TD | 1 |
| Gallagher, KP; Ignasiak, DP; Martin, BJ; McClanahan, TB; Mertz, TE; Saganek, LJ; Van Wylen, DG; Vinten-Johansen, J | 1 |
| Krnjević, K; Zhu, PJ | 1 |
| Alekseev, AE; Gomez, LA; Parkinson, SJ; Terzic, A; Wagner, F; Waldman, SA | 1 |
| Caiolfa, VR; Gill, D; Parola, AH | 1 |
| Anderson, BD; Ho, NF; Singhal, D | 1 |
| Barry, CP; Lind, SE | 1 |
| Iwaki-Egawa, S; Namiki, C; Watanabe, Y | 1 |
| Venton, BJ; Xu, Y | 1 |
3 review(s) available for 9-(2-hydroxy-3-nonyl)adenine and pentostatin
| Article | Year |
|---|---|
Zinc enzymes in medicinal chemistry.
Topics: Chemistry, Pharmaceutical; Enzyme Inhibitors; Enzymes; Humans; Models, Molecular; Zinc | 2021 |
Overview of possible relation of defects in purine metabolism to immune deficiency.
Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Cells, Cultured; Coformycin; Humans; Immunologic Deficiency Syndromes; Immunosuppressive Agents; Pentostatin; Purine Nucleosides; Purine-Nucleoside Phosphorylase; Purine-Pyrimidine Metabolism, Inborn Errors | 1985 |
Does adenosine deaminase inhibition protect ischemic myocardium?
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Enzyme Inhibitors; Humans; In Vitro Techniques; Myocardial Ischemia; Pentostatin; Rabbits | 1994 |
1 trial(s) available for 9-(2-hydroxy-3-nonyl)adenine and pentostatin
| Article | Year |
|---|---|
Inhibition of adenosine deaminase to increase the antitumor activity of adenine nucleoside analogues.
Topics: Adenine; Adenosine Deaminase Inhibitors; Adult; Animals; Carcinoma, Ehrlich Tumor; Clinical Trials as Topic; Coformycin; DNA; Drug Evaluation; Drug Synergism; Humans; Leukemia P388; Leukemia, Experimental; Leukemia, Lymphoid; Male; Mice; Nucleoside Deaminases; Pentostatin; Thymidine; Vidarabine | 1985 |
34 other study(ies) available for 9-(2-hydroxy-3-nonyl)adenine and pentostatin
| Article | Year |
|---|---|
Adenosine deaminase inhibitors. Synthesis and biological evaluation of C1' and nor-C1' derivatives of (+)-erythro-9-(2(S)-hydroxy-3(R)-nonyl)adenine.
Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Binding Sites; Cattle; In Vitro Techniques; Stereoisomerism; Structure-Activity Relationship | 1992 |
Adenosine deaminase inhibitors. Conversion of a single chiral synthon into erythro- and threo-9-(2-hydroxy-3-nonyl)adenines.
Topics: Adenine; Adenosine Deaminase Inhibitors; Chemical Phenomena; Chemistry; Nucleoside Deaminases | 1981 |
Adenosine deaminase inhibitors. Synthesis of deaza analogues of erythro-9-(2-hydroxy-3-nonyl)adenine.
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Cattle; Intestines; Nucleoside Deaminases | 1984 |
Inhibitors of adenosine deaminase. Studies in combining high-affinity enzyme-binding structural units. erythro-1,6-Dihydro-6-(hydroxymethyl)-9-(2-hydroxy-3-nonyl)purine and erythro-9-(2-hydroxy-3-nonyl)purine.
Topics: Adenosine Deaminase Inhibitors; Animals; Cattle; Chemical Phenomena; Chemistry; In Vitro Techniques; Intestinal Mucosa; Kinetics; Nucleoside Deaminases; Purines | 1982 |
Adenosine deaminase inhibitors: synthesis and structure-activity relationships of 2-hydroxy-3-nonyl derivatives of azoles.
Topics: Adenosine Deaminase Inhibitors; Azoles; Chromatography, High Pressure Liquid; Molecular Structure; Stereoisomerism; Structure-Activity Relationship; Triazoles | 1994 |
A unique ring-expanded acyclic nucleoside analogue that inhibits both adenosine deaminase (ADA) and guanine deaminase (GDA; guanase): synthesis and enzyme inhibition studies of 4,6-diamino-8H-1-hydroxyethoxymethyl-8-iminoimidazo[4,5-e][1,3]diazepine.
Topics: Adenosine Deaminase Inhibitors; Animals; Azepines; Enzyme Inhibitors; Guanine Deaminase; Imidazoles; Liver; Rabbits | 2001 |
Structure-based de novo design of non-nucleoside adenosine deaminase inhibitors.
Topics: Adenine; Adenosine Deaminase Inhibitors; Administration, Oral; Animals; Area Under Curve; Drug Design; Enzyme Inhibitors; Humans; Hydrogen Bonding; Injections, Intraperitoneal; Mice; Models, Molecular; Pentostatin; Structure-Activity Relationship | 2003 |
Rat brain adenosine deaminase after 2'-deoxycoformycin administration: biochemical properties and evidence for reduced enzyme levels detected by 2'-[3H]deoxycoformycin ligand binding.
Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Brain; Cattle; Centrifugation, Density Gradient; Intestinal Mucosa; Ligands; Male; Pentostatin; Rats; Rats, Inbred Strains | 1992 |
Niacin prevents DNA strand breakage by adenosine deaminase inhibitors.
Topics: Adenine; Adenosine Deaminase Inhibitors; Cell Line; Cells, Cultured; DNA; DNA Damage; Flow Cytometry; Humans; Kinetics; Lymphocytes; Niacin; Nucleoside Deaminases; Pentostatin | 1990 |
Purine metabolizing enzymes of lymphocyte cell populations: correlation between AMP-deaminase activity and dATP accumulation in murine lymphocytes.
Topics: 5'-Nucleotidase; Adenine; Adenosine Monophosphate; AMP Deaminase; Animals; Bone Marrow; Cells, Cultured; Coformycin; Cytoplasm; Deoxyadenine Nucleotides; Deoxyadenosines; Humans; Lymph Nodes; Lymphocytes; Male; Mice; Nucleotidases; Nucleotide Deaminases; Pentostatin; Phosphotransferases; Spleen; Thymus Gland | 1985 |
Synergistic effect of 3'-deoxyadenosine N1-oxide and adenosine deaminase inhibitors on growth of Ehrlich ascites tumor cells in vivo.
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; Drug Resistance; Drug Synergism; Female; Mice; Nucleoside Deaminases; Pentostatin; Ribonucleosides | 1988 |
Isolation of mutant adenosine deaminase by coformycin affinity chromatography.
Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Cell Line; Chromatography, Affinity; Coformycin; Humans; Lymphocytes; Mutation; Nucleoside Deaminases; Pentostatin | 1986 |
Enhancement of biotinidase activity in mouse serum by inhibitors of methylation.
Topics: Adenine; Adenosine; Amidohydrolases; Animals; Biotinidase; Coformycin; Ethionine; Female; Liver; Methylation; Mice; Pentostatin; Vidarabine | 1987 |
Adenosine deaminase inhibitors enhance cerebral anoxic hyperemia in the rat.
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Brain; Cerebrovascular Circulation; Coformycin; Hyperemia; Hypoxia, Brain; Male; Pentostatin; Rats; Rats, Inbred Strains; Ribonucleosides | 1985 |
Adenosine and hypoxic vasodilatation.
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Cerebrovascular Circulation; Coformycin; Dogs; Hypoxia; Nucleoside Deaminases; Pentostatin; Rats; Ribonucleosides; Vasodilation | 1985 |
Effects of adenosine deaminase inhibitors on lymphocyte-mediated cytolysis.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Cell Line; Coformycin; Cytotoxicity, Immunologic; Immunity, Cellular; Immunosuppressive Agents; Leukemia; Mice; Nucleoside Deaminases; Pentostatin; T-Lymphocytes, Cytotoxic | 1985 |
An analysis of multiple mechanisms of adenosine toxicity in baby hamster kidney cells.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Cell Adhesion; Cell Line; Coformycin; Drug Resistance; Drug Synergism; Guinea Pigs; Homocysteine; Kidney; Nucleotides; Pentostatin; Ribonucleotide Reductases; S-Adenosylhomocysteine; Uridine | 1985 |
Relevance of adenosine deaminase to organ transplantation.
Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Coformycin; Female; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Transplantation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nucleoside Deaminases; Pentostatin; Skin Transplantation; Splenectomy; T-Lymphocytes; Vidarabine | 1985 |
Levels of adenosine deaminase AMP deaminase, and adenylate kinase in cultured human lymphoblast lines: exquisite sensitivity of AMP deaminase to adenosine deaminase inhibitors.
Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenylate Kinase; AMP Deaminase; Cells, Cultured; Coformycin; Humans; Lymphocytes; Nucleoside Deaminases; Nucleotide Deaminases; Pentostatin; Phosphotransferases | 1981 |
Adenosine: a physiological modulator of superoxide anion generation by human neutrophils.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Deaminase; Calcimycin; Cell Aggregation; Coformycin; Cytochalasin B; Cytoplasmic Granules; Depression, Chemical; Dipyridamole; Humans; Methylation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentostatin; Superoxides | 1983 |
B cells as well as T cells form deoxynucleotides from either deoxyadenosine or deoxyguanosine.
Topics: Adenine; Adenosine Deaminase Inhibitors; B-Lymphocytes; Cell Line; Cell Survival; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; Deoxyguanine Nucleotides; Deoxyguanosine; Dose-Response Relationship, Drug; Guanosine; Humans; Pentostatin; Purine-Nucleoside Phosphorylase; T-Lymphocytes | 1984 |
Purinogenic lymphocytotoxicity: clues to a wider chemotherapeutic potential for the adenosine deaminase inhibitors.
Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Cell Survival; Cells, Cultured; Coformycin; Deoxyadenosines; Humans; Interphase; Leukemia; Lymphopenia; Nucleoside Deaminases; Pentostatin; Purines; Ribonucleosides; T-Lymphocytes | 1983 |
Effect of adenosine deaminase inhibitors on the apparent rate of phosphorylation of deoxyadenosine.
Topics: Adenine; Adenosine Deaminase Inhibitors; Cell Line; Coformycin; Deoxyadenosines; Enzyme Inhibitors; Humans; Leukemia, Lymphoid; Nucleoside Deaminases; Pentostatin; Phosphorylation; Vidarabine | 1981 |
Effect of 2'-deoxycoformycin on erythroid, granulocytic, and T-lymphocyte colony growth.
Topics: Adenine; Adenosine Deaminase Inhibitors; Coformycin; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Erythrocytes; Granulocytes; Growth Inhibitors; Humans; Pentostatin; Phytohemagglutinins; Ribonucleosides; T-Lymphocytes | 1981 |
In vitro effects of adenosine deaminase inhibitors on lymphocyte mitogen responsiveness in the mouse.
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Cell Survival; Coformycin; Concanavalin A; Female; Horses; Lipopolysaccharides; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mitogens; Nucleoside Deaminases; Pentostatin; Phytohemagglutinins; Spleen; T-Lymphocytes | 1981 |
Suppression of human lymphocyte DNA and protein synthesis in vitro by adenosine and eight modified adenine nucleosides in the presence or in the absence of adenosine deaminase inhibitors, 2'-deoxycoformycin (DCF) and erythro-9-(2-hydroxy-3-nonyl) adenine
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Blood Proteins; Coformycin; DNA; Humans; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Pentostatin; Phytohemagglutinins | 1982 |
Deoxynucleoside induces neuronal apoptosis independent of neurotrophic factors.
Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Apoptosis; Cell Division; Cell Survival; Cells, Cultured; Chick Embryo; Deoxyadenosines; DNA; Nerve Growth Factors; Neurons; Pentostatin; Sympathetic Nervous System | 1995 |
Endogenous adenosine deaminase does not modulate synaptic transmission in rat hippocampal slices under normoxic or hypoxic conditions.
Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Electrophysiology; Hippocampus; Hypoxia; Pentostatin; Rats; Rats, Sprague-Dawley; Reference Values; Synaptic Transmission; Theophylline | 1994 |
Interruption of Escherichia coli heat-stable enterotoxin-induced guanylyl cyclase signaling and associated chloride current in human intestinal cells by 2-chloroadenosine.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Bacterial Toxins; Caco-2 Cells; Chloride Channels; Enterotoxins; Enzyme Inhibitors; Escherichia coli Proteins; Guanylate Cyclase; Humans; Models, Biological; Pentostatin; Purinergic P1 Receptor Agonists; Signal Transduction | 1997 |
Probing the active site of adenosine deaminase by a pH responsive fluorescent competitive inhibitor.
Topics: Adenine; Adenosine; Adenosine Deaminase; Animals; Binding Sites; Binding, Competitive; Catalysis; Cattle; Enzyme Inhibitors; Fluorescence Polarization; Fluorescent Dyes; Hydrogen-Ion Concentration; Intestines; Kinetics; Molecular Structure; Pentostatin; Protein Binding; Spectrometry, Fluorescence; Spectrophotometry | 1998 |
Absorption and intestinal metabolism of purine dideoxynucleosides and an adenosine deaminase-activated prodrug of 2',3'-dideoxyinosine in the mesenteric vein cannulated rat ileum.
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Anti-HIV Agents; Biological Availability; Biological Transport; Catheterization; Didanosine; Enzyme Inhibitors; Ileum; Intestinal Absorption; Male; Mesenteric Veins; Pentostatin; Permeability; Prodrugs; Purine Nucleosides; Purine-Nucleoside Phosphorylase; Rats; Rats, Sprague-Dawley | 1998 |
Adenosine-mediated killing of cultured epithelial cancer cells.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Apoptosis; Breast Neoplasms; Carcinoma, Squamous Cell; Cell Division; Cell Survival; Coformycin; Deoxyadenosines; Dipyridamole; Enzyme Inhibitors; Female; Humans; Kinetics; Ovarian Neoplasms; Pentostatin; Tumor Cells, Cultured | 2000 |
Adenosine deaminase 2 from chicken liver: purification, characterization, and N-terminal amino acid sequence.
Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Amino Acid Sequence; Animals; Chickens; Enzyme Inhibitors; Enzyme Stability; Isoenzymes; Liver; Molecular Sequence Data; Pentostatin; Protein Structure, Quaternary; RNA-Binding Proteins; Sequence Analysis, Protein; Substrate Specificity | 2004 |
Rapid determination of adenosine deaminase kinetics using fast-scan cyclic voltammetry.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Caffeine; Cattle; Electric Conductivity; Electrochemistry; Enzyme Assays; Kinetics; Oxidation-Reduction; Pentostatin; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Silver; Time Factors | 2010 |