9-(2-hydroxy-3-nonyl)adenine has been researched along with adenosine in 210 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 83 (39.52) | 18.7374 |
| 1990's | 74 (35.24) | 18.2507 |
| 2000's | 40 (19.05) | 29.6817 |
| 2010's | 12 (5.71) | 24.3611 |
| 2020's | 1 (0.48) | 2.80 |
| Authors | Studies |
|---|---|
| Antonini, I; Cristalli, G; Franchetti, P; Grifantini, M; Lupidi, G; Martelli, S; Riva, F | 1 |
| Baker, DC; Woo, PW | 1 |
| Deeprose, RD; Duncan, GS; Harvey, RJ; Wolberg, G; Zimmerman, TP | 1 |
| Chiba, P; Kraupp, M; Müller, MM | 1 |
| Cohen, SS; Plunkett, W | 1 |
| Berne, RM; Coleman, SD; Ely, SW; Matherne, GP | 1 |
| Belt, JA; Cass, CE; Dagnino, L; Gati, WP; Paterson, AR; Vijayalakshmi, D | 1 |
| O'Regan, MH; Perkins, LM; Phillis, JW | 1 |
| Geiger, JD; Gu, JG | 1 |
| Ayers, CR; Feldman, MD; Iflah, S; Linden, J; Patel, A; Ripley, ML; Taylor, HE; Woodward, EB | 1 |
| Cunha, RA; Sebastião, AM | 1 |
| Capuozzo, E; Crifò, C; Salerno, C; Siems, W | 1 |
| Lieberman, M; Wagenknecht, B | 1 |
| Burrier, AC; Jeng, AY; Oei, HH | 1 |
| Dorheim, TA; Hoffman, A; Mentzer, RM; Van Wylen, DG | 1 |
| Carney, DF; Papadimitriou, JC; Shin, ML | 1 |
| Cristalli, G; Eleuteri, A; Franchetti, P; Grifantini, M; Lupidi, G; Vittori, S | 1 |
| Carabaza, A; Ciudad, CJ; Guinovart, JJ; Mor, A; Ricart, MD | 1 |
| Belardinelli, L; Froldi, G | 1 |
| Belardinelli, L; Boykin, MT; Hill, JA; Shryock, JC | 1 |
| de Jong, JW; Opie, LH; Owen, P; van der Meer, P; van Loon, H | 1 |
| Jackson, EK; Kuan, CJ; Wells, JN | 1 |
| Dhillon, GS; Honnor, RC; Londos, C | 1 |
| Church, MK; Hughes, PJ; Vardey, CJ | 1 |
| Butcher, RW; Clark, RB; Proll, MA | 1 |
| Dalaker, K; Prydz, H | 1 |
| Belloni, FL; Gerritsen, ME; Liang, BC | 1 |
| Cespuglio, R; Gharib, A; Reynaud, D; Sarda, N | 1 |
| Bingham, H; Chan, VL; Du, RP; Juranka, P; Pang, JC | 1 |
| Deussen, A; Möser, GH; Schrader, J | 1 |
| Bürrig, KF; Kelm, MK; Kroll, K; Schrader, J | 1 |
| Bittar, N; Fu, LM; Koke, JR; Sun, D; Vaughan, DM | 1 |
| Deussen, A; Lloyd, HG; Schrader, J | 1 |
| Monteiro, EC; Ribeiro, JA | 1 |
| DeMeester, CA; Pike, MC | 1 |
| Meghji, P; Middleton, KM; Newby, AC | 1 |
| Henson, PM; Riches, DW; Stanworth, DR; Watkins, JL | 1 |
| Fredholm, BB; Jonzon, B; Nilsson, J | 1 |
| Dorflinger, LJ; Schonbrunn, A | 1 |
| Feigl, EO; Kroll, K | 1 |
| Aultman, M; Gerrard, TL; Kaplan, AM; Squire, C; Strawson, J | 1 |
| Gudenzi, M; Mustafa, SJ; Nakagawa, Y | 1 |
| Cartner, LA; Holliss, DG; Humphrey, SM | 1 |
| Mohrman, DE | 1 |
| Adams, R; Drachman, DB; Kuncl, RW | 1 |
| Campochiaro, PA; Hackett, SF | 1 |
| Jennings, SR; Lum, CT; Tevethia, SS; Wanner, FJ | 1 |
| Kontinen, VP; Pispa, JP | 1 |
| Brown, P; Gewirtz, H; Most, AS | 1 |
| DeWitt, DF; Heller, LJ; Sparks, HV | 1 |
| Silverstein, SC; Sung, SJ | 1 |
| Rutledge, CO; Samet, MK | 2 |
| Samet, MK | 1 |
| Wolberg, G; Zimmerman, TP | 1 |
| Castaneda, M; Codd, JE; Garvin, PJ; Jellinek, M; Niehoff, M | 1 |
| Archer, S; Chan, VL; Ho, JH; Juranka, PF | 1 |
| Elford, HL; Lin, AL | 1 |
| Cristalli, G; Grifantini, M; Lupidi, G; Marmocchi, F; Riva, F | 1 |
| Achterberg, PW; de Jong, JW | 1 |
| Hirayama, T; Kato, I; Matsuda, F; Noda, M | 1 |
| Achterberg, PW; de Jong, JW; Harmsen, E | 1 |
| Corcoran, T; Huffaker, T; Wagner, JA | 1 |
| Lappin, D; Whaley, K | 1 |
| Cronstein, BN; Hirschhorn, R; Kramer, SB; Weissmann, G | 2 |
| Burnstock, G; Meldrum, LA; Sneddon, P | 1 |
| Chiang, PK; Morita, Y; Siraganian, RP | 1 |
| Morita, Y; Siraganian, RP | 1 |
| Oosterhof, A; Peters, GJ; Veerkamp, JH | 1 |
| Ahl, R | 1 |
| Benyon, RC; Church, MK; Holgate, ST | 1 |
| Ekström, P; Kanje, M | 1 |
| Bardin, CW; Gagnon, C | 1 |
| Green, RD | 2 |
| Deeprose, RD; Duncan, GS; Schmitges, CJ; Wolberg, G; Zimmerman, TP | 1 |
| Aksamit, RR; Backlund, PS | 1 |
| Lum, CT; Robertson, CA; Tilberg, AF; Wanner, FJ | 1 |
| Pasque, MK; Wechsler, AS | 1 |
| Belardinelli, L; Berne, RM; Clemo, HF; DiMarco, JP; Shryock, J; West, GA | 1 |
| Sandberg, G | 1 |
| Collet, H; De Bruyn, CH; Delespesse, G; van Laarhoven, JP | 1 |
| Fredholm, BB; Sollevi, A | 3 |
| Kille, JM; Klabunde, RE | 1 |
| Pike, MC; Snyderman, R | 1 |
| Feinberg, H; Kohler, J; Levitsky, S; Silverman, NA | 1 |
| Eloranta, TO; Raina, AM; Tuomi, K | 1 |
| Hermes, HH; Nabakowski, G; Osswald, H | 1 |
| Hirschhorn, R; Kuritsky, L; Ratech, H; Thorbecke, GJ | 1 |
| Fox, IH; Palella, TD; Schatz, RA; Wilens, TE | 1 |
| Kajander, EO | 1 |
| Fredholm, BB; Lerner, U | 1 |
| Humphrey, SM; Seelye, RN | 1 |
| Gavin, JB; Humphrey, SM; Seelye, RN | 1 |
| Eloranta, TO; Kajander, EO; Raina, AM | 1 |
| Kredich, NM; Pike, MC; Snyderman, R | 1 |
| Einzig, S; Foker, JE; Wang, T | 1 |
| Corsi, C; Fratti, S; Pazzagli, M; Pedata, F; Pepeu, G | 1 |
| Van Belle, H | 1 |
| Fredholm, BB; Lloyd, HG | 1 |
| Abd-Elfattah, AS; Ding, M; Wechsler, AS | 1 |
| Abd-Elfattah, AS; Jessen, ME; Wechsler, AS | 1 |
| Abd-Elfattah, AS; Wechsler, AS | 1 |
| Lautt, WW; Zhang, YL | 1 |
| Doyle, MP; Duling, BR; Linden, J | 1 |
| Abd-Elfattah, AS; Bolli, R; Jeroudi, MO; Sekili, S; Sun, JZ; Tang, XL; Zughaib, ME | 1 |
| Kessel, D; Zemlicka, J | 1 |
| Dunwiddie, TV; Lupica, CR; Mitchell, JB | 1 |
| Sciotti, VM; Van Wylen, DG | 1 |
| Meno, JR; Ngai, AC; Winn, HR | 1 |
| Lasley, RD; Mentzer, RM | 1 |
| Pazzagli, M; Pedata, F; Pepeu, G | 1 |
| Geiger, JD; Gu, JG; Kala, G | 1 |
| Dubey, RK; Gillespie, DG; Jackson, EK; Mi, Z; Suzuki, F | 1 |
| Bengtsson, T; Grenegård, M; Stendahl, O; Zalavary, S | 1 |
| Hernandez, ML; Martinez, MJ; Ochoa, B | 1 |
| Geiger, JD; Gu, JG; Nath, A | 1 |
| Correia-de-Sá, P; Ribeiro, JA | 1 |
| Downey, HF; Lee, SC; Mallet, RT | 1 |
| Larsen, AK; Osborne, NN | 1 |
| Alekseev, AE; Gomez, LA; Parkinson, SJ; Terzic, A; Wagner, F; Waldman, SA | 1 |
| Monteiro, EC; Monteiro, TC; Silva e Sousa, MA; Vera-Cruz, P | 1 |
| Ishikawa, S; Okada, Y; Saijoh, K | 1 |
| Barth, A; Janigro, D; Meno, JR; Newell, DW; Nguyen, LB; Wender, R; Winn, HR | 1 |
| Brause, M; Delabar, U; Eckardt, KU; Gleiter, CH; Zebski, H | 1 |
| Oliveira, CR; Rego, AC; Santos, MS | 1 |
| Dubey, RK; Gillespie, DG; Jackson, EK; Mi, Z | 2 |
| Abushanab, E; Barankiewicz, J; Danks, AM; Fox, A; Makings, L; Marangos, PJ; Pragnacharyulu, PV; Wallis, RA; Wiemann, T | 1 |
| Dubey, RK; Gillespie, DG; Jackson, EK | 2 |
| Caiolfa, VR; Gill, D; Parola, AH | 1 |
| Kalsi, KK; Kochan, Z; Smolenski, RT; Yacoub, MH; Zych, M | 1 |
| Kobayashi, T; Okada, Y; Yamada, T | 1 |
| Manthei, SA; Reiling, CM; Van Wylen, DG | 1 |
| Abd-Elfattah, AS; Jessen, ME; Lekven, J; Wechsler, AS | 1 |
| Kalsi, KK; Smolenski, RT; Yacoub, MH | 2 |
| Job, RF; Minor, TR; Woodson, JC | 1 |
| Kalsi, K; Kochan, Z; Smolenski, RT; Yacoub, MH; Zych, M | 1 |
| Jackson, EK; Kusaka, H; Li, P; Tofovic, SP | 1 |
| Ashraf, M; Hirai, K | 1 |
| Fukamachi, M; Morita, T; Motoyashiki, T; Shiomi, H; Ueki, H | 1 |
| Li, KM; Lloyd, HG; Ludowyke, RI; Ross, L | 1 |
| Brundege, JM; Dunwiddie, TV | 1 |
| Cristalli, G; Lupidi, G; Marmocchi, F | 1 |
| IJzerman, AP; Pavan, B | 1 |
| Richardt, G; Schreieck, J | 1 |
| Aoki, M; Narimatsu, E | 1 |
| Deussen, A; Kelm, M; Schäfer, S; Stappert, M | 1 |
| Flavin, MP; Ho, LT | 1 |
| O'Regan, MH; Phillis, JW; Song, D | 1 |
| Dale, TJ; Dupere, JR; Starkey, SJ; Xie, X | 1 |
| Callaghan, F; Hourani, SM; Tennant, JP; Turner, C | 1 |
| Dubey, RK; Gillespie, DG; Jackson, EK; Shue, H | 1 |
| Headrick, JP; Hinschen, AK; Rose'Meyer, RB | 1 |
| Barry, CP; Lind, SE | 1 |
| Eng, KH; Min, HW; Moochhala, S | 1 |
| Aden, U; Berman, RF; Fredholm, BB; O'Connor, WT | 1 |
| Dhalla, AK; Dodam, JR; Johnson, LR; Jones, AW; Laughlin, MH; Magliola, L; Rubin, LJ | 1 |
| Abe, Y; Fujisawa, Y; Fukui, T; He, H; Kimura, S; Miura, K; Nishiyama, A; Rahman, M | 1 |
| Antonyan, A; Armenyan, A; Cristalli, G; Lupidi, G; Mardanyan, S; Sharoyan, S | 1 |
| Lee, JJ; Parsons, ME; Talubmook, C | 1 |
| Carcillo, JA; Jackson, EK; Tofovic, SP; Zacharia, L | 1 |
| Cerniway, RJ; Headrick, JP; Matherne, GP; Peart, J | 1 |
| Abunasra, H; Jayakumar, J; Kalsi, KK; Raisky, O; Slominska, EM; Smolenski, RT; Suzuki, K; Yacoub, MH | 1 |
| Andrew, CM; Ciccarelli, R; Crocker, CE; Di Iorio, P; Kleywegt, S; Rathbone, MP; Traversa, U; Werstiuk, ES | 1 |
| Asaka, Y; Hara, A; Ito, Z; Kusakari, J; Tabuchi, K; Tsuji, S | 1 |
| O'Donnell, JM; Suvarna, NU | 1 |
| Brackenborough, KT; Duffy, C; Hagan, RM; Jones, SA; Morgan, PF; Pratt, GD; Sargent, RS; Southam, E; Stratton, SC | 1 |
| Alfinito, PD; Alli, R; Townes-Anderson, E | 1 |
| Benton, HP; Kollias-Baker, C; MacDonald, MH; Tesch, AM | 1 |
| Deussen, A; Lauer, T; Loncar, R | 1 |
| Bernard, EA; de Souza, LF; Gelain, DP | 1 |
| Hentschel, S; Lewerenz, A; Nieber, K | 1 |
| Boons, GJ; Hasko, G; Leibovich, SJ; Pinhal-Enfield, G; Ramanathan, M; Salzman, AL; Vogel, SN | 1 |
| Knowles, AF; Wen, LT | 1 |
| Lobo, MG; Ribeiro, JA; Sebastião, AM | 1 |
| Gerth, A; Hauschildt, S; Kronstein, R; Nieber, K; Thiele, A; Wetzel, A | 1 |
| Cseppento, A; Gesztelyi, R; Hajdú, P; Szabó, JZ; Szentmiklósi, AJ; Zsuga, J | 1 |
| Nagai, K; Nakagawa, K; Nishizaki, T; Saitoh, M; Yamamoto, S; Yamamura, T | 1 |
| Choi, JW; Ko, KH; Yoo, BK; Yoon, SY | 1 |
| Handy, DE; Loscalzo, J; Zhang, Y | 1 |
| Cherubini, E; Giniatullin, R; Kasyanov, AM; Safiulina, VF | 1 |
| Ghavami, S; Hashemi, M; Karami-Tehrani, F; Los, M; Maddika, S | 1 |
| Roberts, EL | 1 |
| Chambers, MG; Mason, RM; Mistry, D | 1 |
| Agarwal, A; Giles, GI; Hock, T; Johnson, KK; Kelley, EE; Khoo, NK; Lancaster, JR; Powell, PC; Richardson, GR; Tarpey, MM | 1 |
| Adães, S; Correia-de-Sá, P; Duarte-Araújo, M; Magalhães-Cardoso, T; Nascimento, C; Timóteo, MA; Vieira, C | 1 |
| Ashton, KJ; Blackburn, MR; Headrick, JP; Matherne, GP; Peart, JN; Reichelt, ME; Willems, L | 1 |
| Hirsch, S; Llanos, M; Ronco, AM; Tamayo, D | 1 |
| Baggott, JE; Morgan, SL | 1 |
| Bogo, MR; Bonan, CD; Dias, RD; Rico, EP; Rosemberg, DB; Senger, MR; Souza, DO | 1 |
| Sheppy, E; Wong, T; Wu, C; Wu, X; Zhang, L | 1 |
| Boison, D; Li, T; Shen, HY | 1 |
| Nishizaki, T; Saito, M; Yaguchi, T; Yasuda, Y | 1 |
| Venton, BJ; Xu, Y | 1 |
| Allen-Gipson, DS; Blackburn, MR; Bluitt, DL; Jarrell, JC; Schneider, DJ; Sisson, JH; Wyatt, TA; Yanov, D; Zhang, H | 1 |
| Biragyn, A; Ferrucci, L; Goetzl, EJ; Hesdorffer, CS; Kennedy, RT; Longo, DL; Mabrouk, OS; Madara, K; Malchinkhuu, E; Schwartz, JB; Taub, DD | 1 |
| Buyukdeligoz, M; Hocaoglu, N; Kalkan, S; Oransay, K; Tuncok, Y | 1 |
| Dobson, JG; Fenton, RA | 1 |
| Martins, DF; Mazzardo-Martins, L; Piovezan, AP; Santos, AR; Soldi, F; Stramosk, J | 1 |
| Bonan, CD; Bortolotto, JW; Cognato, Gde P; Melo, GM; Vianna, MR | 1 |
| Gotoh, A; Kanno, T; Kuribayashi, K; Nagaya, T; Nakajima, Y; Nakano, T; Nishizaki, T | 1 |
| Ito, S; Kon, Y; Otsuguro, K; Otsuka, S; Tomonari, Y; Yamaguchi, S | 1 |
| Faingold, CL; Kommajosyula, SP; Randall, ME | 1 |
| Da Silva, RS; Lutte, AH; Majolo, JH | 1 |
3 review(s) available for 9-(2-hydroxy-3-nonyl)adenine and adenosine
| Article | Year |
|---|---|
The possible role of protein-carboxyl methylation in sperm motility and capacitation.
Topics: Adenine; Adenosine; Animals; Dyneins; Homocysteine; Humans; Infertility, Male; Male; Methylation; Mitochondria; Protein Methyltransferases; Protein O-Methyltransferase; Sperm Capacitation; Sperm Motility; Spermatogenesis; Spermatozoa; Testis | 1982 |
Chemotaxis and methylation in a macrophage cell line.
Topics: Adenine; Adenosine; Animals; Blood Proteins; Cell Line; Chemotaxis, Leukocyte; Guinea Pigs; Humans; Macrophages; Methylation; Mice; Phosphatidylethanolamines; Rabbits; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1983 |
Metabolic intervention to affect myocardial recovery following ischemia.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Aminoimidazole Carboxamide; Animals; Citric Acid Cycle; Coronary Circulation; Coronary Disease; Fructosediphosphates; Glucose; Glycogen; Heart; Humans; Inosine; Myocardium; Oxidative Phosphorylation; Ribonucleosides; Ribose | 1984 |
207 other study(ies) available for 9-(2-hydroxy-3-nonyl)adenine and adenosine
| Article | Year |
|---|---|
Adenosine deaminase inhibitors. Synthesis of deaza analogues of erythro-9-(2-hydroxy-3-nonyl)adenine.
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Cattle; Intestines; Nucleoside Deaminases | 1984 |
Inhibitors of adenosine deaminase. Studies in combining high-affinity enzyme-binding structural units. erythro-1,6-Dihydro-6-(hydroxymethyl)-9-(2-hydroxy-3-nonyl)purine and erythro-9-(2-hydroxy-3-nonyl)purine.
Topics: Adenosine Deaminase Inhibitors; Animals; Cattle; Chemical Phenomena; Chemistry; In Vitro Techniques; Intestinal Mucosa; Kinetics; Nucleoside Deaminases; Purines | 1982 |
Inhibition of immune cell function by adenosine: biochemical studies.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenine; Adenosine; Animals; Cytotoxicity, Immunologic; Homocysteine; Imidazoles; Lymphocytes; Methionine; Mice; S-Adenosylmethionine; Theophylline; Uridine | 1979 |
Uptake of adenosine in human erythrocytes.
Topics: Adenine; Adenosine; Biological Transport; Erythrocytes; Humans; Kinetics; Temperature | 1979 |
Two approaches that increase the activity of analogs of adenine nucleosides in animal cells.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Animals; Carcinoma, Ehrlich Tumor; Deamination; Deoxyadenine Nucleotides; Deoxyadenosines; Dideoxynucleotides; DNA; Drug Synergism; L Cells; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Nucleoside Deaminases; Phosphates; Purine Nucleosides; RNA; Thymidine; Uridine; Vidarabine | 1975 |
Inhibition of adenosine metabolism increases myocardial interstitial adenosine concentrations and coronary flow.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Coronary Circulation; Extracellular Space; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Myocardium; Perfusion; Tubercidin; Vascular Resistance | 1992 |
L1210/B23.1 cells express equilibrative, inhibitor-sensitive nucleoside transport activity and lack two parental nucleoside transport activities.
Topics: Adenine; Adenosine; Animals; Antiviral Agents; Biological Transport; Carrier Proteins; Cell Membrane; Clone Cells; Formycins; Kinetics; Leukemia L1210; Membrane Proteins; Mice; Mutagenesis; Nucleoside Transport Proteins; Nucleosides; Thioinosine; Thymidine; Tumor Cells, Cultured; Vidarabine | 1992 |
Measurement of rat plasma adenosine levels during normoxia and hypoxia.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Animals; Blood Pressure; Carbon Dioxide; Chromatography, High Pressure Liquid; Dipyridamole; Edetic Acid; Egtazic Acid; Hydrogen-Ion Concentration; Hypoxia; Male; Oxygen; Phosphorylation; Rats; Rats, Inbred Strains | 1992 |
Transport and metabolism of D-[3H]adenosine and L-[3H]adenosine in rat cerebral cortical synaptoneurosomes.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Biological Transport; Cerebral Cortex; Neurons; Rats; Stereoisomerism; Synaptosomes; Tritium; Tubercidin | 1992 |
The precise radioimmunoassay of adenosine: minimization of sample collection artifacts and immunocrossreactivity.
Topics: Adenine; Adenosine; Artifacts; Automation; Chromatography, High Pressure Liquid; Cross Reactions; Humans; Immunosuppressive Agents; Molecular Structure; Radioimmunoassay; Sensitivity and Specificity; Temperature | 1992 |
Extracellular metabolism of adenine nucleotides and adenosine in the innervated skeletal muscle of the frog.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cations; Coformycin; Dipyridamole; In Vitro Techniques; Inosine Monophosphate; Kinetics; Muscles; Piperazines; Rana ridibunda; Sodium-Potassium-Exchanging ATPase; Thioinosine | 1991 |
Effect of adenosine on the membrane potential changes of human neutrophils triggered by the tripeptide F-Met-Leu-Phe.
Topics: Adenine; Adenosine; Adenosine Deaminase; Calcium; Cell Membrane; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Kinetics; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils | 1991 |
Adenine nucleotide degradation in cultured chick heart muscle cells.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Chick Embryo; Chromatography, High Pressure Liquid; Dipyridamole; Glycolysis; Inosine; Myocardium; Oxidative Phosphorylation; Phosphorylation; Thioinosine | 1991 |
5-Amino-4-imidazolecarboxamide riboside raises adenosine in perfused hypoxic rat heart.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Aminoimidazole Carboxamide; Animals; Cardiac Output; Coronary Circulation; Heart; Hypoxia; Inosine; Male; Myocardium; Perfusion; Rats; Rats, Inbred Strains; Ribonucleosides | 1991 |
Enhanced interstitial fluid adenosine attenuates myocardial stunning.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Coronary Disease; Dogs; Extracellular Space; Female; Hemodynamics; Male; Time Factors; Ventricular Function | 1991 |
Inhibitors of membrane lipid metabolism enhance complement-mediated nucleated cell killing through distinct mechanisms.
Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Acylation; Adenine; Adenosine; Adenosine Triphosphate; Animals; Carcinoma, Ehrlich Tumor; Complement C9; Complement Membrane Attack Complex; Complement System Proteins; Cytotoxicity, Immunologic; Flow Cytometry; Homocysteine; Immunosuppressive Agents; L-Lactate Dehydrogenase; Membrane Lipids; Methylation; Mice; Thimerosal | 1991 |
Adenosine deaminase inhibitors: synthesis and structure-activity relationships of imidazole analogues of erythro-9-(2-hydroxy-3-nonyl)adenine.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Aminoimidazole Carboxamide; Animals; Binding Sites; Cattle; Chemical Phenomena; Chemistry; Intestines; Molecular Structure; Structure-Activity Relationship; Tubercidin | 1991 |
Role of AMP on the activation of glycogen synthase and phosphorylase by adenosine, fructose, and glutamine in rat hepatocytes.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Enzyme Activation; Fructose; Glutamine; Glycogen Synthase; Kinetics; Liver; Male; Models, Biological; Phosphorylase a; Phosphorylases; Rats; Rats, Inbred Strains | 1990 |
Species-dependent effects of adenosine on heart rate and atrioventricular nodal conduction. Mechanism and physiological implications.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Atrioventricular Node; Bundle of His; Depression, Chemical; Dipyridamole; Female; Guinea Pigs; Heart Atria; Heart Block; Heart Rate; Hypoxia; Male; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Xanthines | 1990 |
A new method of sampling blood for measurement of plasma adenosine.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Blood Specimen Collection; Carbon Radioisotopes; Catheterization; Dipyridamole; Humans | 1990 |
Adenosine as adjunct to potassium cardioplegia: effect on function, energy metabolism, and electrophysiology.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Drug Combinations; Electrophysiology; Energy Metabolism; Heart; Heart Arrest, Induced; Potassium; Potassium Compounds; Rats | 1990 |
Endogenous adenosine restrains renin release in conscious rats.
Topics: Adenine; Adenosine; Adenosine Deaminase; Animals; Hydralazine; Hypertension, Renovascular; Male; Rats; Rats, Inbred Strains; Renin; Xanthines | 1990 |
cAMP-dependent protein kinase and lipolysis in rat adipocytes. I. Cell preparation, manipulation, and predictability in behavior.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Adenosine Deaminase; Adipose Tissue; Animals; Isoproterenol; Kinetics; Lipolysis; Male; Phenylisopropyladenosine; Protein Kinases; Rats; Rats, Inbred Strains; Seasons; Starvation | 1985 |
Studies on the receptor mediating cyclic AMP-independent enhancement by adenosine of IgE-dependent mediator release from rat mast cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenine Nucleotides; Adenosine; Animals; Cyclic AMP; Dose-Response Relationship, Drug; Immunoglobulin E; In Vitro Techniques; Male; Mast Cells; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Serotonin; Tachyphylaxis; Theophylline; Time Factors; Tubercidin | 1986 |
A1 and A2 adenosine receptors regulate adenylate cyclase in cultured human lung fibroblasts.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Cell Line; Cyclic AMP; Fibroblasts; Humans; Lung; Receptors, Cell Surface; Receptors, Purinergic; Theophylline; Virulence Factors, Bordetella | 1986 |
Effect of some drugs on thromboplastin activity in mouse trophoblast cells in vitro and in vivo.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Animals; Calcium Channel Blockers; Dinoprostone; Felodipine; Female; Gallic Acid; Methylation; Mice; Monensin; Nifedipine; Nitrendipine; Pregnancy; Prostaglandins E; Thromboplastin; Trophoblasts; Tubercidin; Verapamil | 1986 |
Effects of alkylxanthines and calcium antagonists on adenosine uptake by cultured rabbit coronary microvascular endothelium.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium Channel Blockers; Cells, Cultured; Coronary Vessels; Dipyridamole; Endothelium; Ethanol; Isoproterenol; Male; Microcirculation; Rabbits; Theophylline; Trifluoperazine; Xanthines | 1987 |
[Role of hypothalamic adenosinergic systems in regulating states of wakefulness in the rat].
Topics: Adenine; Adenosine; Animals; Hypothalamus; Hypothalamus, Posterior; Immunosuppressive Agents; Male; Piperazines; Rats; Rats, Inbred Strains; Sleep; Wakefulness | 1989 |
Imbalance of purine nucleotides in alanosine-resistant baby hamster kidney cells.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Kinase; Adenylosuccinate Lyase; Adenylosuccinate Synthase; Alanine; Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Cricetinae; Culture Media; Humans; Hypoxanthine Phosphoribosyltransferase; Mutation; Phosphotransferases; Purines; Selection, Genetic; Transformation, Genetic; Uridine | 1989 |
Turnover of adenosine in plasma of human and dog blood.
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosylhomocysteinase; Animals; Blood Flow Velocity; Dipyridamole; Dogs; Forearm; Half-Life; Humans; Hydrolases; Nucleotidases; Tritium | 1989 |
Transendothelial transport and metabolism of adenosine and inosine in the intact rat aorta.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aorta; Endothelium, Vascular; Female; Inosine; Male; Muscle, Smooth, Vascular; Purines; Rats; Rats, Inbred Strains; Tritium | 1989 |
Inhibitors of adenosine catabolism improve recovery of dog myocardium after ischemia.
Topics: Adenine; Adenosine; Animals; Dipyridamole; Dogs; Drug Combinations; Energy Metabolism; Female; Free Radicals; Male; Myocardial Contraction; Myocardial Reperfusion Injury | 1989 |
Contribution of S-adenosylhomocysteine to cardiac adenosine formation.
Topics: Adenine; Adenosine; Animals; Guinea Pigs; Heart; Homocysteine; In Vitro Techniques; Kinetics; Models, Theoretical; Myocardium; Perfusion; S-Adenosylhomocysteine | 1989 |
Adenosine deaminase and adenosine uptake inhibitions facilitate ventilation in rats.
Topics: Adenine; Adenosine; Adenosine Deaminase; Animals; Carotid Arteries; Carotid Body; Chemoreceptor Cells; Dipyridamole; Injections; Nucleoside Deaminases; Rats; Rats, Inbred Strains; Respiration; Stimulation, Chemical; Xanthines | 1989 |
Inhibition of phosphoinositide metabolism in human polymorphonuclear leukocytes by S-adenosylhomocysteine.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Homocysteine; Humans; In Vitro Techniques; Kinetics; Neutrophils; Phosphatidylinositols; S-Adenosylhomocysteine; Type C Phospholipases | 1988 |
Absolute rates of adenosine formation during ischaemia in rat and pigeon hearts.
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Deaminase; Adenosine Kinase; Adult; AMP Deaminase; Animals; Columbidae; Coronary Disease; Female; Heart; Histocytochemistry; Humans; Male; Middle Aged; Myocardium; Nucleotidases; Nucleotides; Phosphoric Monoester Hydrolases; Rats; Rats, Inbred Strains; Species Specificity; Tubercidin | 1988 |
Regulation of macrophage lysosomal secretion by adenosine, adenosine phosphate esters, and related structural analogues of adenosine.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Esterases; Homocysteine; Kinetics; Lysosomes; Macrophages; Male; Mice; Receptors, Cell Surface; Receptors, Purinergic; Secretory Rate; Structure-Activity Relationship; Theophylline; Tubercidin | 1985 |
Adenosine receptor-mediated changes in cyclic AMP production and DNA synthesis in cultured arterial smooth muscle cells.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; DNA Replication; Muscle, Smooth, Vascular; Phenylisopropyladenosine; Platelet-Derived Growth Factor; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic | 1985 |
Adenosine inhibits prolactin and growth hormone secretion in a clonal pituitary cell line.
Topics: Adenine; Adenosine; Adenosine Deaminase; Animals; Carbachol; Cell Line; Chromatography, High Pressure Liquid; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; Dipyridamole; Growth Hormone; Phenylisopropyladenosine; Pituitary Gland; Pituitary Neoplasms; Prolactin; Rats; Thyrotropin-Releasing Hormone; Vasoactive Intestinal Peptide | 1985 |
Adenosine is unimportant in controlling coronary blood flow in unstressed dog hearts.
Topics: Adenine; Adenosine; Adenosine Deaminase; Animals; Coronary Circulation; Dogs; Female; Hemodynamics; Histamine; Lymph; Male; Mathematics; Receptors, Cell Surface; Receptors, Purinergic; Regional Blood Flow; Substrate Specificity; Vasodilation | 1985 |
Role of adenosine deaminase in human monocyte differentiation and tumor cell cytotoxicity.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Antibody-Dependent Cell Cytotoxicity; Carcinoma, Transitional Cell; Cell Differentiation; Cell Line; Cytotoxicity, Immunologic; Homocysteine; Humans; Lymphokines; Macrophage Activation; Monocytes; Nucleoside Deaminases; Phagocytosis; Superoxides; Urinary Bladder Neoplasms | 1985 |
Calcium entry blocking activity of dilazep in dog coronary artery.
Topics: Adenine; Adenosine; Adenosine Deaminase; Animals; Arteries; Azepines; Calcium; Calcium Channel Blockers; Coronary Vessels; Dilazep; Diltiazem; Dipyridamole; Dogs; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Lidoflazine; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1986 |
The influence of inhibitors of the ATP degradative pathway on recovery of function and high energy phosphate after transient ischemia in the rat heart.
Topics: 5'-Nucleotidase; Acute Disease; Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Adenylate Kinase; Animals; Coronary Circulation; Coronary Disease; Dinucleoside Phosphates; Male; Nucleotidases; Rats; Rats, Inbred Strains; Thioinosine | 1986 |
Adenosine handling in interstitia of cremaster muscle studied by bioassay.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arterioles; Biological Assay; Cricetinae; Diffusion; Dipyridamole; Extracellular Space; Kinetics; Methods; Muscles; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Thioinosine; Vasodilation | 1988 |
Inhibition of methyltransferase reduces the turnover of acetylcholine receptors.
Topics: Adenine; Adenosine; Animals; Dose-Response Relationship, Drug; Endocytosis; Homocysteine; In Vitro Techniques; Methionine; Methyltransferases; Muscles; Myasthenia Gravis; Phospholipids; Rats; Receptors, Nicotinic | 1988 |
Implication of protein carboxymethylation in retinal pigment epithelial cell chemotaxis.
Topics: Adenine; Adenosine; Chemotaxis; Eye Proteins; Fibronectins; Homocysteine; Humans; Hydrolysis; Methanol; Pigment Epithelium of Eye; Platelet-Derived Growth Factor; Protein Methyltransferases; Protein O-Methyltransferase | 1988 |
Inhibition of T cell cytotoxicity by cyclosporine (CSA), adenosine (Ado) and an inhibitor of adenosine deaminase (ADA).
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Animals; Cyclosporins; Cytotoxicity, Immunologic; Drug Synergism; In Vitro Techniques; Male; Mice; T-Lymphocytes, Cytotoxic | 1986 |
Enhancement of biotinidase activity in mouse serum by inhibitors of methylation.
Topics: Adenine; Adenosine; Amidohydrolases; Animals; Biotinidase; Coformycin; Ethionine; Female; Liver; Methylation; Mice; Pentostatin; Vidarabine | 1987 |
Measurement of plasma adenosine concentration: methodological and physiological considerations.
Topics: Adenine; Adenosine; Dipyridamole; Erythrocytes; False Positive Reactions; Hemolysis; Humans; Indicators and Reagents; Radioisotope Dilution Technique; Tritium | 1987 |
Transient increase in release of adenosine during rapid cardiac pacing; transient effects on overdrive suppression of ventricular automaticity.
Topics: Adenine; Adenosine; Animals; Cardiac Pacing, Artificial; Electrocardiography; Heart Rate; Heart Ventricles; In Vitro Techniques; Male; Myocardium; Oxygen Consumption; Rats; Rats, Inbred Strains; Theophylline | 1987 |
Inhibition of macrophage phagocytosis by methylation inhibitors. Lack of correlation of protein carboxymethylation and phospholipid methylation with phagocytosis.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Cells, Cultured; Deoxyadenosines; Homocysteine; Kinetics; Macrophages; Methylation; Mice; Phagocytosis; Phospholipids; Proteins; Vidarabine | 1985 |
Antagonism of the positive chronotropic effect of norepinephrine by purine nucleosides in rat atria.
Topics: Adenine; Adenosine; Animals; Deoxyadenosines; Heart Atria; Heart Rate; Inosine; Male; Norepinephrine; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Stimulation, Chemical | 1985 |
Inhibition of antibody production by 2-chloroadenosine.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Antibody Formation; B-Lymphocytes; Cells, Cultured; DNA Replication; Homocysteine; Immunosuppressive Agents; Lymphocyte Activation; Male; Methylation; Mice; S-Adenosylmethionine | 1985 |
Effects of adenosine deaminase inhibitors on lymphocyte-mediated cytolysis.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Cell Line; Coformycin; Cytotoxicity, Immunologic; Immunity, Cellular; Immunosuppressive Agents; Leukemia; Mice; Nucleoside Deaminases; Pentostatin; T-Lymphocytes, Cytotoxic | 1985 |
An experimental evaluation of nucleotide enhancement techniques for kidney transplantation.
Topics: Adenine; Adenosine; Animals; Dipyridamole; Dogs; Female; Graft Survival; Kidney; Kidney Transplantation; Nucleotides; Organ Preservation; Transplantation, Autologous | 1985 |
An analysis of multiple mechanisms of adenosine toxicity in baby hamster kidney cells.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Cell Adhesion; Cell Line; Coformycin; Drug Resistance; Drug Synergism; Guinea Pigs; Homocysteine; Kidney; Nucleotides; Pentostatin; Ribonucleotide Reductases; S-Adenosylhomocysteine; Uridine | 1985 |
Adenosine deaminase impairment and ribonucleotide reductase in human cells.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Cell Division; Deoxyadenosines; HeLa Cells; Humans; Interphase; Nucleoside Deaminases; Ribonucleotide Reductases; Thymine Nucleotides | 1985 |
Inhibition of adenosine deaminase from several sources by deaza derivatives of adenosine and EHNA.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Antiviral Agents; Erythrocytes; Escherichia coli; Humans; Kinetics; Nucleoside Deaminases; Saccharomyces cerevisiae; Structure-Activity Relationship | 1985 |
Adenosine deaminase inhibition and myocardial adenosine metabolism during ischemia.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Monophosphate; Animals; Coronary Circulation; Coronary Disease; Inosine Monophosphate; Male; Myocardial Contraction; Myocardium; Nucleoside Deaminases; Purines; Rats; Rats, Inbred Strains | 1985 |
An early effect of the S component of staphylococcal leukocidin on methylation of phospholipid in various leukocytes.
Topics: Adenine; Adenosine; Animals; Cell Survival; Enzyme Activation; Homocysteine; Leukocidins; Membrane Lipids; Methylation; Neutrophils; Phospholipases A; Phospholipases A2; Phospholipids; Rabbits; Staphylococcus | 1985 |
Adenosine deaminase inhibition and myocardial purine release during normoxia and ischaemia.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Monophosphate; Animals; Coronary Circulation; Deamination; Depression, Chemical; Heart; Male; Myocardium; Nucleoside Deaminases; Oxygen Consumption; Perfusion; Purines; Rats; Rats, Inbred Strains | 1985 |
Adenosine inhibits cell division and promotes neurite extension in PC12 cells.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenylyl Cyclases; Animals; Axons; Cell Division; Cell Line; Cyclic AMP; Drug Synergism; Nerve Growth Factors; Neurons; Receptors, Cell Surface; Receptors, Purinergic | 1984 |
Adenosine A2 receptors on human monocytes modulate C2 production.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Complement C2; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Immunosuppressive Agents; Monocytes; Phenylisopropyladenosine; Receptors, Cell Surface; Receptors, Purinergic; Tubercidin | 1984 |
A new physiological function for adenosine: regulation of superoxide anion production.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Anions; Calcimycin; Concanavalin A; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1983 |
Control of transmitter release in guinea-pig vas deferens by prejunctional P1-purinoceptors.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Triphosphate; Animals; Dipyridamole; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Neurotransmitter Agents; Norepinephrine; Receptors, Neurotransmitter; Receptors, Purinergic; Theophylline; Vas Deferens | 1984 |
Effect of inhibitors of transmethylation on histamine release from human basophils.
Topics: Adenine; Adenosine; Basophils; Calcimycin; Histamine Release; Homocysteine; Humans; Immunoglobulin E; In Vitro Techniques; Methylation; Ribonucleosides; S-Adenosylmethionine; Tubercidin | 1981 |
Inhibition of IgE-mediated histamine release from rat basophilic leukemia cells and rat mast cells by inhibitors of transmethylation.
Topics: Adenine; Adenosine; Animals; Basophils; Female; Histamine Release; Homocysteine; Immunoglobulin E; Leukemia; Mast Cells; Methylation; Mice; Rabbits; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1981 |
Effects of adenosine and deoxyadenosine on PHA-stimulation of lymphocytes of man, horse and pig.
Topics: Adenine; Adenosine; Adult; Animals; Deoxyadenosines; Horses; Humans; In Vitro Techniques; Lymphocytes; Phosphoribosyl Pyrophosphate; Phytohemagglutinins; Species Specificity; Swine; Thymidine; Uridine | 1982 |
Effect of inhibitors of methylation on early and late interferon synthesis in bovine kidney cell cultures.
Topics: Adenine; Adenosine; Animals; Cattle; Cells, Cultured; Cycloheximide; Cycloleucine; Homocysteine; Interferons; Methylation; Newcastle disease virus; Poly I-C; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine | 1981 |
The effect of methyltransferase inhibitors on histamine release from human dispersed lung mast cells activated with anti-human IgE and calcium ionophore A23187.
Topics: Adenine; Adenosine; Antibodies, Anti-Idiotypic; Calcimycin; Histamine Release; Humans; Immunoglobulin E; Mast Cells; Membrane Lipids; Methylation; Methyltransferases; Phospholipids; Ribonucleosides; S-Adenosylmethionine; Tubercidin | 1984 |
Inhibition of fast axonal transport by erythro-9-[3-(2-hydroxynonyl)]adenine.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Axonal Transport; Cycloleucine; Deoxyadenosines; Rana esculenta; Rana temporaria; Sciatic Nerve; Thionucleosides | 1984 |
Effects of exogenous adenosine deaminase and erythro-9-(2-hydroxy-3-nonyl) adenine on intracellular cyclic AMP levels in C1300 murine neuroblastoma in tissue culture.
Topics: Adenine; Adenosine; Adenosine Deaminase; Animals; Cell Line; Culture Techniques; Cyclic AMP; Dipyridamole; Mice; Neoplasms, Experimental; Neuroblastoma; Nucleoside Deaminases; Theophylline | 1980 |
Adenosine transport by a variant of C1300 murine neuroblastoma cells deficient in adenosine kinase.
Topics: Adenine; Adenosine; Adenosine Kinase; Animals; Biological Transport; Cell Line; Genetic Variation; Kinetics; Mice; Neuroblastoma; Phosphotransferases; Purines; Structure-Activity Relationship | 1980 |
Inhibition of lymphocyte-mediated cytolysis and cyclic AMP phosphodiesterase by erythro-9-(2-hydroxy-3-nonyl)adenine.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenylyl Cyclases; Animals; Immunosuppressive Agents; In Vitro Techniques; Mice; S-Adenosylhomocysteine; T-Lymphocytes, Cytotoxic | 1982 |
Adenosine: a physiological modulator of superoxide anion generation by human neutrophils.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Deaminase; Calcimycin; Cell Aggregation; Coformycin; Cytochalasin B; Cytoplasmic Granules; Depression, Chemical; Dipyridamole; Humans; Methylation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentostatin; Superoxides | 1983 |
Cyclosporine-induced adenosine triphosphate depletion in murine T and B lymphocytes.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Animals; B-Lymphocytes; Cell Separation; Chromatography, High Pressure Liquid; Cyclosporins; Female; Fluorescent Antibody Technique; Mice; Mice, Inbred C57BL; Spleen; T-Lymphocytes | 1984 |
Effects of adenosine and adenine nucleotides on the atrioventricular node of isolated guinea pig hearts.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Aminophylline; Animals; Atrioventricular Node; Atropine; Dipyridamole; Dose-Response Relationship, Drug; Electrophysiology; Guinea Pigs; Heart Block; Heart Conduction System; In Vitro Techniques; Nucleosides; Time Factors | 1984 |
Correlations between phospholipid methylation and neuronal catecholamine transport.
Topics: Adenine; Adenosine; Animals; Biological Transport; Cerebral Cortex; Cytosol; Homocysteine; Kinetics; Male; Membrane Lipids; Methylation; Norepinephrine; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; Synaptosomes | 1984 |
Regulation of thymocyte proliferation by endogenous adenosine and adenosine deaminase.
Topics: Adenine; Adenosine; Adenosine Deaminase; Animals; Cells, Cultured; Dipyridamole; DNA; Guinea Pigs; Lymphocyte Activation; Nucleoside Deaminases; Phenylisopropyladenosine; T-Lymphocytes; Theophylline | 1983 |
Selective inhibition of various mitogen responses in human lymphocytes.
Topics: Adenine; Adenosine; B-Lymphocytes; DNA Replication; Humans; Immunosuppressive Agents; Lymphocyte Activation; Mitogens; T-Lymphocytes | 1984 |
Influence of adenosine on the vascular responses to sympathetic nerve stimulation in the canine subcutaneous adipose tissue.
Topics: Adenine; Adenosine; Adipose Tissue; Animals; Body Temperature; Dipyridamole; Dogs; Electric Stimulation; Female; Homeostasis; Inosine; Norepinephrine; Propranolol; Regional Blood Flow; Sympathetic Nervous System; Theophylline; Vascular Resistance; Vasoconstriction | 1983 |
Adenosine as a mediator of postcontraction hyperemia in dog gracilis muscle.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Animals; Dipyridamole; Dogs; Electric Conductivity; Female; Male; Muscle Contraction; Muscles; Oxygen Consumption; Perfusion | 1984 |
Transmethylation reactions are required for initial morphologic and biochemical responses of human monocytes to chemoattractants.
Topics: Adenine; Adenosine; Arachidonic Acid; Arachidonic Acids; Chemical Phenomena; Chemistry; Chemoreceptor Cells; Chemotaxis, Leukocyte; Homocysteine; Humans; Kinetics; Lipid Metabolism; Methylation; Monocytes | 1981 |
Beneficial metabolic effect of nucleoside augmentation on reperfusion injury following cardioplegic arrest.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Animals; Coronary Circulation; Dogs; Heart Arrest, Induced; Myocardium; Phosphocreatine | 1983 |
Uptake and utilization of 5'-methylthioadenosine by cultured baby-hamster kidney cells.
Topics: Adenine; Adenosine; Animals; Cell Division; Cell Line; Cricetinae; Deoxyadenosines; Kidney; Thionucleosides; Tubercidin | 1982 |
Role of adenosine in signal transmission of tubuloglomerular feedback.
Topics: Adenine; Adenosine; Angiotensin II; Animals; Dipyridamole; Dogs; Feedback; Glomerular Filtration Rate; Hydrostatic Pressure; Kidney Glomerulus; Kidney Tubules; Vasoconstriction | 1982 |
Suppression of human lymphocyte DNA and protein synthesis in vitro by adenosine and eight modified adenine nucleosides in the presence or in the absence of adenosine deaminase inhibitors, 2'-deoxycoformycin (DCF) and erythro-9-(2-hydroxy-3-nonyl) adenine
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Blood Proteins; Coformycin; DNA; Humans; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Pentostatin; Phytohemagglutinins | 1982 |
S-Adenosylhomocysteine accumulation and selective cytotoxicity in cultured T- and B-lymphocytes.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosylhomocysteinase; B-Lymphocytes; Cell Division; Cells, Cultured; Deoxyadenosines; Homocysteine; Humans; Hydrolases; Nucleoside Deaminases; S-Adenosylhomocysteine; T-Lymphocytes | 1982 |
Inactivation of liver S-adenosylhomocysteine hydrolase in vitro of rats treated with erythro-9-(2-hydroxynon-3-yl)adenine.
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Animals; Deoxyadenosines; Enzyme Activation; Female; Hydrolases; Kinetics; Liver; Rats; Rats, Inbred Strains; Temperature | 1982 |
Metabolism of adenosine and 2'-deoxy-adenosine by fetal mouse calvaria in culture.
Topics: Adenine; Adenosine; Animals; Bone and Bones; Culture Media; Deoxyadenosines; Dilazep; Dipyridamole; Hypoxanthine; Hypoxanthines; Inosine; Mice; Organ Culture Techniques | 1982 |
Improved functional recovery of ischemic myocardium by suppression of adenosine catabolism.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Heart Arrest, Induced; In Vitro Techniques; Male; Myocardium; Perfusion; Rats; Rats, Inbred Strains | 1982 |
The influence of adenosine on the no-reflow phenomenon in anoxic and ischaemic hearts.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Coronary Circulation; Coronary Disease; Dilatation, Pathologic; Kinetics; Male; Oxygen; Perfusion; Rats; Rats, Inbred Strains | 1982 |
Effect of 9-beta-D-arabinofuranosyladenine and erythro-9-(2-hydroxy-3-nonyl) adenine on the metabolism of S-adenosylhomocysteine, S-adenosylmethionine, and adenosine in rat liver.
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Animals; Female; Homocysteine; Hydrolases; Liver; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Vidarabine | 1982 |
Role of transmethylation reactions in cellular motility and phagocytosis.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adult; Animals; Cell Movement; Chemotaxis, Leukocyte; Depression, Chemical; Guinea Pigs; Humans; In Vitro Techniques; Lactones; Macrophages; Methylation; Models, Biological; Monocytes; Peptides; Phagocytosis; Phospholipids; S-Adenosylhomocysteine; S-Adenosylmethionine | 1980 |
Role of adenosine in adipose tissue circulation.
Topics: Adenine; Adenosine; Adipose Tissue; Animals; Capillary Permeability; Dilazep; Dipyridamole; Dogs; Female; Inosine; Vascular Resistance; Vasodilator Agents | 1981 |
The antilipolytic effect of endogenous and exogenous adenosine in canine adipose tissue in situ.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adipose Tissue; Animals; Dilazep; Dipyridamole; Dogs; Female; Lipolysis | 1981 |
Adenosine metabolism and myocardial preservation. Consequences of adenosine catabolism on myocardial high-energy compounds and tissue blood flow.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Cardiopulmonary Bypass; Dogs; Heart Arrest, Induced; Myocardium; Phosphocreatine; Regional Blood Flow | 1980 |
Regulation of extracellular adenosine levels in the striatum of aging rats.
Topics: 2-Amino-5-phosphonovalerate; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Aging; Amino Acids; Animals; Corpus Striatum; Enzyme Inhibitors; Extracellular Space; Male; Microdialysis; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tubercidin | 1995 |
Adenosine transformation by human red blood cell membranes.
Topics: Adenine; Adenosine; Erythrocyte Membrane; Humans; Piperazines | 1995 |
Involvement of adenosine deaminase and adenosine kinase in regulating extracellular adenosine concentration in rat hippocampal slices.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Basal Metabolism; Electric Stimulation; Hippocampus; In Vitro Techniques; Male; Purines; Rats; Tubercidin | 1995 |
Intermittent aortic crossclamping prevents cumulative adenosine triphosphate depletion, ventricular fibrillation, and dysfunction (stunning): is it preconditioning?
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Animals; Aorta; Constriction; Dogs; Inosine; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardial Stunning; Myocardium; Thioinosine; Ventricular Dysfunction, Left; Ventricular Fibrillation; Ventricular Function, Left | 1995 |
Nucleoside trapping during reperfusion prevents ventricular dysfunction, "stunning," in absence of adenosine. Possible separation between ischemic and reperfusion injury.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Affinity Labels; Animals; Biological Transport, Active; Dogs; Female; Inosine; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Stunning; Purinones; Random Allocation; Thioinosine; Ventricular Function, Left | 1994 |
Separation between ischemic and reperfusion injury by site specific entrapment of endogenous adenosine and inosine using NBMPR and EHNA.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Dogs; Female; Heart; Inosine; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Thioinosine; Ventricular Function, Left | 1994 |
Release and regulation of endogenous adenosine during hemorrhage.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Blood Pressure; Cats; Chromatography, High Pressure Liquid; Dilazep; Drug Interactions; Female; Hemorrhage; Male | 1994 |
Nucleoside-induced arteriolar constriction: a mast cell-dependent response.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Affinity Labels; Animals; Arterioles; Cricetinae; Dose-Response Relationship, Drug; In Vitro Techniques; Inosine; Male; Mast Cells; Mesocricetus; Methylene Blue; Mouth; Muscle, Smooth, Vascular; p-Methoxy-N-methylphenethylamine; Purinergic P1 Receptor Antagonists; Thioinosine; Vasoconstriction | 1994 |
Augmentation of endogenous adenosine attenuates myocardial 'stunning' independently of coronary flow or hemodynamic effects.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Coronary Circulation; Dogs; Heart; Hemodynamics; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Stunning; Nucleosides; Thioinosine | 1993 |
Accumulation and metabolism of adenallene by murine leukemia L1210 cells.
Topics: Adenine; Adenosine; Animals; Antiviral Agents; Biological Transport; Biotransformation; Cytosine; Kinetics; Leukemia L1210; Mice; Temperature; Thymine; Tritium; Tumor Cells, Cultured | 1994 |
Activity-dependent release of endogenous adenosine modulates synaptic responses in the rat hippocampus.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Animals; Baclofen; Electric Stimulation; Electrophysiology; Evoked Potentials; Hippocampus; Male; Purinergic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Purinergic; Synapses; Theophylline | 1993 |
Increases in interstitial adenosine and cerebral blood flow with inhibition of adenosine kinase and adenosine deaminase.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Brain; Cerebrovascular Circulation; Dialysis Solutions; Dose-Response Relationship, Drug; Extracellular Space; Hypoxanthine; Hypoxanthines; Inosine; Male; Rats; Rats, Wistar; Tubercidin | 1993 |
Changes in pial arteriolar diameter and CSF adenosine concentrations during hypoxia.
Topics: Adenine; Adenosine; Animals; Arterioles; Cerebrovascular Circulation; Dipyridamole; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine; Male; Pia Mater; Rats; Rats, Sprague-Dawley; Vasodilation | 1993 |
Adenosine increases lactate release and delays onset of contracture during global low flow ischaemia.
Topics: Adenine; Adenosine; Animals; Glucose; Lactates; Lactic Acid; Male; Myocardial Contraction; Myocardial Ischemia; Rats; Rats, Wistar; Xanthines | 1993 |
Effect of K+ depolarization, tetrodotoxin, and NMDA receptor inhibition on extracellular adenosine levels in rat striatum.
Topics: 2-Amino-5-phosphonovalerate; Adenine; Adenosine; Amino Acids; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dipyridamole; Male; Perfusion; Potassium; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 1993 |
[3H]adenosine transport in synaptoneurosomes of postmortem human brain.
Topics: Adenine; Adenosine; Aged; Biological Transport; Cadaver; Cerebral Cortex; Dilazep; Dipyridamole; Female; Humans; Kinetics; Male; Synaptosomes; Time Factors; Tritium; Tubercidin | 1993 |
Smooth muscle cell-derived adenosine inhibits cell growth.
Topics: Adenine; Adenosine; Animals; Cell Division; Cells, Cultured; Dipyridamole; DNA Replication; Enzyme Inhibitors; Male; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley | 1996 |
Release of oxygen metabolites from chemoattractant-stimulated neutrophils is inhibited by resting platelets: role of extracellular adenosine and actin polymerization.
Topics: Actin Cytoskeleton; Actins; Adenine; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Biological Factors; Blood Platelets; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Culture Media, Conditioned; Cytochalasin B; Humans; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Purinergic P1 Receptor Antagonists; Reactive Oxygen Species; Receptors, Purinergic P1; Respiratory Burst; Theophylline | 1996 |
Role of adenine nucleotides in the activation of microsomal cholesterol ester hydrolase by fructose or adenosine in rat hepatocytes.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; AMP Deaminase; Animals; Cells, Cultured; Enzyme Activation; Female; Fructose; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Sterol Esterase | 1996 |
Characterization of inhibitor-sensitive and -resistant adenosine transporters in cultured human fetal astrocytes.
Topics: Adenine; Adenosine; Affinity Labels; Astrocytes; Biological Transport; Carrier Proteins; Cells, Cultured; Dilazep; Dipyridamole; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fetus; Humans; Kinetics; Membrane Proteins; Nucleoside Transport Proteins; Thioinosine; Tritium; Tubercidin; Vasodilator Agents | 1996 |
Adenosine uptake and deamination regulate tonic A2a receptor facilitation of evoked [3H]acetylcholine release from the rat motor nerve terminals.
Topics: Acetylcholine; Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Affinity Labels; Animals; Deamination; Diaphragm; Electric Stimulation; Enzyme Inhibitors; Female; In Vitro Techniques; Male; Motor Neurons; Phrenic Nerve; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, Purinergic P1; Thioinosine | 1996 |
Endogenous adenosine increases O2 utilisation efficiency in isoprenaline-stimulated canine myocardium.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adrenergic beta-Agonists; Animals; Dogs; Hypoxia; Isoproterenol; Lactic Acid; Myocardial Contraction; Myocardial Ischemia; Myocardium; Oxygen; Oxygen Consumption; Perfusion; Stimulation, Chemical | 1996 |
Involvement of adenosine in retinal ischemia. Studies on the rat.
Topics: Adenine; Adenosine; Adenosine Deaminase; Animals; Calbindin 2; Dyneins; Electroretinography; Enzyme Inhibitors; Eye Proteins; Fluorescent Antibody Technique, Indirect; Glial Fibrillary Acidic Protein; Ischemia; Phenylisopropyladenosine; Rats; Receptors, Purinergic P1; Reperfusion Injury; Retinal Vessels; S100 Calcium Binding Protein G | 1996 |
Interruption of Escherichia coli heat-stable enterotoxin-induced guanylyl cyclase signaling and associated chloride current in human intestinal cells by 2-chloroadenosine.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Bacterial Toxins; Caco-2 Cells; Chloride Channels; Enterotoxins; Enzyme Inhibitors; Escherichia coli Proteins; Guanylate Cyclase; Humans; Models, Biological; Pentostatin; Purinergic P1 Receptor Agonists; Signal Transduction | 1997 |
Adenosine increases the cAMP content of the rat carotid body in vitro.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenine; Adenosine; Animals; Carotid Body; Cyclic AMP; Male; Nerve Tissue Proteins; Perfusion; Phenethylamines; Rats; Rats, Wistar; Receptors, Purinergic P1; Second Messenger Systems | 1996 |
Endogenous adenosine facilitates neurotransmission via A2A adenosine receptors in the rat superior colliculus in vivo.
Topics: Adenine; Adenosine; Animals; Electrophysiology; Enzyme Inhibitors; Purinergic Antagonists; Purines; Rats; Receptors, Purinergic P1; RNA, Messenger; Superior Colliculi; Synaptic Transmission; Xanthines | 1997 |
Neurotoxicity in organotypic hippocampal slices mediated by adenosine analogues and nitric oxide.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Animals, Newborn; Brain Ischemia; Cell Survival; Enzyme Inhibitors; Hippocampus; Neurons; Neurotoxins; Nitric Oxide; Organ Culture Techniques; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theobromine; Theophylline; Xanthines | 1997 |
Evidence against a major role of adenosine in oxygen-dependent regulation of erythropoietin in rats.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Animals; Antihypertensive Agents; Carbon Monoxide; Dipyridamole; Diuretics; Drug Synergism; Enzyme Inhibitors; Erythropoietin; Gene Expression; Hypoxia; Kidney; Male; Oxygen; Phenethylamines; Phosphodiesterase Inhibitors; Piperazines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; RNA, Messenger; Theophylline; Vasodilator Agents; Xanthines | 1997 |
Adenosine triphosphate degradation products after oxidative stress and metabolic dysfunction in cultured retinal cells.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Cell Hypoxia; Cells, Cultured; Chick Embryo; Enzyme Inhibitors; Glucose; Hypoxanthine; Inosine; Iodoacetates; Iodoacetic Acid; Ischemia; Kinetics; Oligomycins; Oxidative Stress; Retina; Thioinosine | 1997 |
Exogenous and endogenous adenosine inhibits fetal calf serum-induced growth of rat cardiac fibroblasts: role of A2B receptors.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Adenosine-5'-(N-ethylcarboxamide); Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Cattle; Cell Division; Culture Media; Dipyridamole; DNA Replication; Enzyme Inhibitors; Fibroblasts; Heart; Male; Myocardium; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Tubercidin; Xanthines | 1997 |
Regulation of adenosine concentration and cytoprotective effects of novel reversible adenosine deaminase inhibitors.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Astrocytoma; Cattle; Cytoprotection; Endothelium, Vascular; Enzyme Inhibitors; Hippocampus; Humans; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured | 1997 |
Cyclic AMP-adenosine pathway induces nitric oxide synthesis in aortic smooth muscle cells.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Animals; Aorta, Thoracic; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytosol; Dideoxyadenosine; Enzyme Inhibitors; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Signal Transduction; Thionucleotides | 1998 |
Adenosine inhibits growth of human aortic smooth muscle cells via A2B receptors.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adult; Animals; Aorta, Thoracic; Cell Division; Cells, Cultured; Collagen; Dipyridamole; DNA; Humans; Kinetics; Male; Muscle, Smooth, Vascular; Phenethylamines; Purinergic P1 Receptor Antagonists; Rats; Receptor, Adenosine A2B; Receptors, Purinergic P1; Thymidine; Xanthines | 1998 |
Probing the active site of adenosine deaminase by a pH responsive fluorescent competitive inhibitor.
Topics: Adenine; Adenosine; Adenosine Deaminase; Animals; Binding Sites; Binding, Competitive; Catalysis; Cattle; Enzyme Inhibitors; Fluorescence Polarization; Fluorescent Dyes; Hydrogen-Ion Concentration; Intestines; Kinetics; Molecular Structure; Pentostatin; Protein Binding; Spectrometry, Fluorescence; Spectrophotometry | 1998 |
Adenine/ribose supply increases adenosine production and protects ATP pool in adenosine kinase-inhibited cardiac cells.
Topics: Adenine; Adenosine; Adenosine Kinase; Adenosine Triphosphate; Animals; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Heart; In Vitro Techniques; Kinetics; Male; Myocardium; Purines; Rats; Rats, Sprague-Dawley; Ribose; Tubercidin; Uridine | 1998 |
The levels of adenosine and its metabolites in the guinea pig and rat brain during complete ischemia-in vivo study.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Brain; Brain Chemistry; Brain Ischemia; Chromatography, High Pressure Liquid; Dyneins; Enzyme Inhibitors; Guinea Pigs; Hypoxanthine; Inosine; Male; Microwaves; Rats; Rats, Wistar; Spectrophotometry, Ultraviolet; Tissue Fixation | 1998 |
Dual cardiac microdialysis to assess drug-induced changes in interstitial purine metabolites: adenosine deaminase inhibition versus adenosine kinase inhibition.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Chromatography, High Pressure Liquid; Extracellular Space; Hypoxanthine; Inosine; Male; Microdialysis; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Rabbits; Tubercidin | 1998 |
Differential cardioprotection with selective inhibitors of adenosine metabolism and transport: role of purine release in ischemic and reperfusion injury.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Biological Transport; Carrier Proteins; Dogs; Enzyme Inhibitors; Membrane Proteins; Models, Cardiovascular; Myocardial Ischemia; Myocardial Reperfusion Injury; Nucleoside Transport Proteins; Purines; Thioinosine | 1998 |
Effects of nucleoside transport inhibitors and adenine/ribose supply on ATP concentration and adenosine production in cardiac myocytes.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Biological Transport; Carrier Proteins; Dipyridamole; Enzyme Inhibitors; Membrane Proteins; Myocardium; NAD; Nucleoside Transport Proteins; Rats; Rats, Sprague-Dawley; Ribose; Thioinosine | 1998 |
Inhibition of adenosine deaminase by erythro-9-(2-hydroxy-3-nonyl)adenine (EHNA) mimics the effect of inescapable shock on escape learning in rats.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Analysis of Variance; Animals; Caffeine; Central Nervous System Stimulants; Electroshock; Enzyme Inhibitors; Escape Reaction; Fear; Helplessness, Learned; Male; Neural Inhibition; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Reaction Time; Restraint, Physical; Stress, Psychological | 1998 |
Effects of nucleoside transport inhibitors and adenine/ribose on ATP concentration and adenosine production in cardiac myocytes.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Animals; Biological Transport; Cells, Cultured; Dipyridamole; Heart; Myocardium; Rats; Rats, Sprague-Dawley; Thioinosine | 1998 |
Effects of adenine/ribose supply on adenosine production and ATP concentration in adenosine kinase inhibited cardiac cells.
Topics: Adenine; Adenosine; Adenosine Kinase; Adenosine Triphosphate; Animals; Cells, Cultured; Endothelium, Vascular; Heart; Kinetics; Myocardium; Rats; Rats, Sprague-Dawley; Ribose | 1998 |
Effects of adenosine deaminase inhibition on blood pressure in old spontaneously hypertensive rats.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Aging; Animals; Blood Pressure; Enzyme Inhibitors; Hemodynamics; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Xanthines | 1998 |
Modulation of adenosine effects in attenuation of ischemia and reperfusion injury in rat heart.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Enzyme Inhibitors; Heart; Heart Rate; In Vitro Techniques; Isoenzymes; L-Lactate Dehydrogenase; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Organophosphates; Purines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Stroke Volume; Superoxides; Thioinosine; Xanthine Oxidase | 1998 |
Involvement of adenosine in vanadate-stimulated release of lipoprotein lipase activity.
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenylyl Cyclases; Adipose Tissue; Animals; Enzyme Inhibitors; Extracellular Space; In Vitro Techniques; Lipoprotein Lipase; Male; Rats; Rats, Wistar; Stimulation, Chemical; Vanadates | 1998 |
Evidence that IgE receptor stimulation increases adenosine release from rat basophilic leukaemia (RBL-2H3) cells.
Topics: Adenine; Adenosine; Animals; beta-N-Acetylhexosaminidases; Cytoplasmic Granules; Leukemia, Basophilic, Acute; Mast Cells; Purinergic P1 Receptor Agonists; Rats; Receptor, Adenosine A3; Receptors, IgE; Serotonin; Tubercidin; Tumor Cells, Cultured | 1998 |
Metabolic regulation of endogenous adenosine release from single neurons.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Dinucleoside Phosphates; Drug Administration Routes; Electric Stimulation; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Models, Biological; Neurons; Patch-Clamp Techniques; Purinergic P1 Receptor Antagonists; Pyramidal Cells; Rats; Theophylline; Tubercidin | 1998 |
Inhibition studies on membrane adenosine deaminase from human placenta.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Cell Membrane; Chromatography, Affinity; Erythrocytes; Female; Humans; Placenta; Pregnancy; Ultracentrifugation | 1998 |
Adenosine inhibits collagen and total protein synthesis in vascular smooth muscle cells.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Animals; Aorta, Abdominal; Cells, Cultured; Collagen; Cyclic AMP; Dipyridamole; Kinetics; Leucine; Male; Muscle, Smooth, Vascular; Proline; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Xanthines | 1999 |
Processing of adenosine receptor agonists in rat and human whole blood.
Topics: Adenine; Adenosine; Adenosine Kinase; Aminohydrolases; Animals; Blood; Deoxyadenosines; Enzyme Inhibitors; Humans; Purinergic P1 Receptor Agonists; Rats; Thioinosine | 1998 |
Endogenous adenosine reduces the occurrence of ischemia-induced ventricular fibrillation in rat heart.
Topics: Adenine; Adenosine; Aminoimidazole Carboxamide; Animals; Caffeine; Creatine Kinase; Electrocardiography; Enzyme Inhibitors; Hypoxanthine; Inosine; Male; Myocardial Ischemia; Myocardium; Perfusion; Rats; Rats, Wistar; Reperfusion Injury; Ribonucleosides; Theophylline; Thioinosine; Thiophenes; Time Factors; Ventricular Fibrillation; Xanthines | 1999 |
Involvement of the adenosine neuromodulatory system in the benzodiazepine-induced depression of excitatory synaptic transmissions in rat hippocampal neurons in vitro.
Topics: Adenine; Adenosine; Aminophylline; Animals; Benzodiazepines; Bicuculline; Dentate Gyrus; Dipyridamole; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; GABA Antagonists; Hippocampus; Midazolam; Neurons; Neurotransmitter Agents; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Synaptic Transmission | 1999 |
Quantification of extracellular and intracellular adenosine production: understanding the transmembranous concentration gradient.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Biological Transport; Bradykinin; Coronary Circulation; Cytosol; Depression, Chemical; Dipyridamole; Drug Synergism; Enzyme Inhibitors; Extracellular Space; Guinea Pigs; Heart; Models, Biological; Myocardium; Osmolar Concentration; Oxygen; Oxygen Consumption; Piperazines; Thioinosine; Tubercidin | 1999 |
Propentofylline protects neurons in culture from death triggered by macrophage or microglial secretory products.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Cell Death; Cell Hypoxia; Cell Survival; Cells, Cultured; Culture Media, Conditioned; Fetus; Hippocampus; Macrophages, Peritoneal; Mice; Microglia; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Xanthines | 1999 |
Further evidence for the role of adenosine in hypercapnia/acidosis-evoked coronary flow regulation.
Topics: Acidosis; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Carbon Dioxide; Coronary Circulation; Enzyme Inhibitors; Heart Rate; Hypercapnia; Male; Myocardial Contraction; Rats; Rats, Sprague-Dawley; Time Factors; Tubercidin; Vasodilator Agents | 1999 |
The anticonvulsant BW534U87 depresses epileptiform activity in rat hippocampal slices by an adenosine-dependent mechanism and through inhibition of voltage-gated Na+ channels.
Topics: Action Potentials; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Anticonvulsants; Brain Chemistry; CHO Cells; Cricetinae; Electrophysiology; Enzyme Inhibitors; Epilepsy; Female; Hippocampus; In Vitro Techniques; Ion Channel Gating; Magnesium; Male; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sodium Channels; Triazoles | 1999 |
Effects of allopurinol, erythro-9-(2-hydroxy-3-nonyl)adenine and S-(4-nitrobenzyl)-6-thioinosine on the degradation of adenosine 5'-triphosphate in the rat colon muscularis mucosae.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Allopurinol; Animals; Colon; Enzyme Inhibitors; Half-Life; In Vitro Techniques; Intestinal Mucosa; Muscle, Smooth; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Thioinosine | 1999 |
A(2B) receptors mediate antimitogenesis in vascular smooth muscle cells.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Kinase; Adenosine-5'-(N-ethylcarboxamide); Animals; Anticoagulants; Antihypertensive Agents; Aorta, Abdominal; Becaplermin; Cell Division; Dinucleoside Phosphates; Enzyme Inhibitors; Hyperplasia; Male; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Oligonucleotides, Antisense; Phenethylamines; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-2; Thymidine; Tritium; Tubercidin; Vasodilator Agents; Xanthines | 2000 |
Age-related changes in A(1)-adenosine receptor-mediated bradycardia.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Aging; Animals; Bradycardia; Enzyme Inhibitors; Male; Rats; Rats, Wistar; Receptors, Purinergic P1; Tritium | 2000 |
Adenosine-mediated killing of cultured epithelial cancer cells.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Apoptosis; Breast Neoplasms; Carcinoma, Squamous Cell; Cell Division; Cell Survival; Coformycin; Deoxyadenosines; Dipyridamole; Enzyme Inhibitors; Female; Humans; Kinetics; Ovarian Neoplasms; Pentostatin; Tumor Cells, Cultured | 2000 |
Adenosine and its receptor agonists regulate nitric oxide production and RAW 264.7 macrophages via both receptor binding and its downstream metabolites-inosine.
Topics: Adenine; Adenosine; Bacterial Toxins; Cell Line; Dose-Response Relationship, Drug; Dyneins; Enterotoxins; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Humans; Hypoxanthine; Inosine; Lipopolysaccharides; Macrophages; Nitric Oxide; Nitric Oxide Synthase; Purinergic P1 Receptor Agonists | 2000 |
Evidence for increased dorsal hippocampal adenosine release and metabolism during pharmacologically induced seizures in rats.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Bicuculline; Convulsants; Disease Models, Animal; Electroencephalography; Enzyme Inhibitors; Excitatory Amino Acid Agonists; GABA Antagonists; Guanosine; Hippocampus; Hypoxanthine; Inosine; Kainic Acid; Male; Microdialysis; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures; Xanthine | 2000 |
Selective transport of adenosine into porcine coronary smooth muscle.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Animals; Biological Transport; Carrier Proteins; Coronary Vessels; Dinoprost; Dipyridamole; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Female; In Vitro Techniques; Muscle, Smooth, Vascular; Purinergic P1 Receptor Agonists; Substrate Specificity; Swine; Thioinosine; Vasoconstriction; Vasodilation; Vasodilator Agents | 2000 |
Renal interstitial adenosine metabolism during ischemia in dogs.
Topics: Adenine; Adenosine; Animals; Antibiotics, Antineoplastic; Dogs; Extracellular Space; Hypoxanthine; Inosine; Ischemia; Kidney; Tubercidin | 2001 |
Tryptophan environment in adenosine deaminase. I. Enzyme modification with N-bromosuccinimide in the presence of adenosine and EHNA analogues.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Binding Sites; Brain; Bromosuccinimide; Cattle; Enzyme Inhibitors; Kinetics; Protein Conformation; Spleen; Tryptophan | 2001 |
Activation of presynaptic A1-receptors by endogenous adenosine inhibits acetylcholine release in the guinea-pig ileum.
Topics: Acetylcholine; Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Cholinergic Fibers; Dipyridamole; Dose-Response Relationship, Drug; Electrophysiology; Enzyme Inhibitors; Female; Guinea Pigs; Ileum; Isotope Labeling; Male; Models, Biological; Muscle Contraction; Muscle, Smooth; Receptors, Purinergic P1; Vasodilator Agents; Xanthines | 2001 |
Inhibition of adenosine deaminase attenuates endotoxin-induced release of cytokines in vivo in rats.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Blood Pressure; Caffeine; Catecholamines; Cytokines; Endotoxemia; Endotoxins; Enzyme Inhibitors; Heart; Heart Rate; Male; Propranolol; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Renin; Xanthines | 2001 |
Cardioprotection with adenosine metabolism inhibitors in ischemic-reperfused mouse heart.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Enzyme Inhibitors; Female; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Perfusion; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Tubercidin | 2001 |
Protection from reperfusion injury after cardiac transplantation by inhibition of adenosine metabolism and nucleotide precursor supply.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Cardioplegic Solutions; Creatinine; Deoxyadenosines; Enzyme Inhibitors; Heart Transplantation; In Vitro Techniques; Inflammation; Male; Myocardial Reperfusion Injury; Myocardium; Neutrophil Infiltration; Perfusion; Rats; Rats, Sprague-Dawley; Ribose; Treatment Outcome | 2001 |
Mechanisms of apoptosis induced by purine nucleosides in astrocytes.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Apoptosis; Astrocytes; Carrier Proteins; Cells, Cultured; Central Nervous System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Guanine; Guanosine; Hypoxanthine; Inosine; Male; Purine Nucleosides; Purinergic P1 Receptor Antagonists; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A3; Receptors, Purinergic P1; RNA, Messenger | 2002 |
Does endogenous or exogenous adenosine facilitate the functional recovery of the cochlea after ischemia?
Topics: Action Potentials; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Cochlea; Enzyme Inhibitors; Guinea Pigs; Ischemia; Recovery of Function; Reperfusion Injury; Time Factors; Vasodilator Agents | 2002 |
Hydrolysis of N-methyl-D-aspartate receptor-stimulated cAMP and cGMP by PDE4 and PDE2 phosphodiesterases in primary neuronal cultures of rat cerebral cortex and hippocampus.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Adenosine; Animals; Cells, Cultured; Cerebral Cortex; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 2; Cyclic Nucleotide Phosphodiesterases, Type 4; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Guanylate Cyclase; Hippocampus; N-Methylaspartate; Neurons; Nitric Oxide Donors; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Rolipram | 2002 |
Broad spectrum anticonvulsant activity of BW534U87: possible role of an adenosine-dependent mechanism.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Amygdala; Animals; Anticonvulsants; Convulsants; Dose-Response Relationship, Drug; Electroshock; Enzyme Inhibitors; Female; Kindling, Neurologic; Male; Mice; Pentylenetetrazole; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Seizures; Triazoles; Xanthines | 2002 |
Adenosine A(2a) receptor-mediated inhibition of rod opsin mRNA expression in tiger salamander.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenylyl Cyclases; Ambystoma; Animals; Cells, Cultured; Colforsin; Darkness; Enzyme Inhibitors; Gene Expression Regulation; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2A; Receptors, Purinergic P1; Retina; Retinal Rod Photoreceptor Cells; RNA, Messenger; Rod Opsins | 2002 |
Effects of an adenosine kinase inhibitor and an adenosine deaminase inhibitor on accumulation of extracellular adenosine by equine articular chondrocytes.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Cartilage, Articular; Chondrocytes; Enzyme Inhibitors; Horses; Lipopolysaccharides; Nitric Oxide; Nitrites; Tubercidin | 2002 |
Tracer adenosine: a novel myocardial flow marker.
Topics: Adenine; Adenosine; Alprostadil; Animals; Carbon Radioisotopes; Coronary Circulation; Dogs; Isotope Labeling; Microspheres; Myocardial Ischemia; Myocardium; Sensitivity and Specificity; Statistics as Topic; Ventricular Dysfunction, Left | 2003 |
Extracellular purines from cells of seminiferous tubules.
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Animals; Cells, Cultured; Dipyridamole; Enzyme Inhibitors; Extracellular Space; Germ Cells; Kinetics; Male; Paracrine Communication; Phosphodiesterase Inhibitors; Purines; Rats; Rats, Wistar; Receptors, Purinergic; Seminiferous Tubules; Sertoli Cells; Thioinosine | 2003 |
Activation of A(3) receptors by endogenous adenosine inhibits synaptic transmission during hypoxia in rat cortical neurons.
Topics: Adenine; Adenosine; Animals; Cell Hypoxia; Cerebral Cortex; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Guanosine; Guanosine Diphosphate; In Vitro Techniques; Male; Neurotransmitter Uptake Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyramidal Cells; Rats; Rats, Wistar; Receptor, Adenosine A3; Receptors, Purinergic P1; Synaptic Transmission; Thionucleosides; Thionucleotides; Time Factors | 2003 |
An angiogenic switch in macrophages involving synergy between Toll-like receptors 2, 4, 7, and 9 and adenosine A(2A) receptors.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Angiogenesis Inhibitors; Animals; Cells, Cultured; DNA-Binding Proteins; Endothelial Growth Factors; Enzyme Inhibitors; Humans; Intercellular Signaling Peptides and Proteins; Lipopolysaccharides; Lipoproteins; Lymphokines; Macrophages, Peritoneal; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Physiologic; NF-kappa B; Paclitaxel; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2A; Receptors, Cell Surface; Receptors, Purinergic P1; Toll-Like Receptor 2; Toll-Like Receptor 3; Toll-Like Receptor 4; Toll-Like Receptor 5; Toll-Like Receptor 7; Toll-Like Receptor 9; Toll-Like Receptors; Tumor Necrosis Factor-alpha; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vasodilator Agents | 2003 |
Extracellular ATP and adenosine induce cell apoptosis of human hepatoma Li-7A cells via the A3 adenosine receptor.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Apoptosis; Biological Transport; Carcinoma, Hepatocellular; Caspase 3; Caspases; Cell Division; Cell Line; Cell Line, Tumor; Coformycin; Dipyridamole; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Humans; In Situ Nick-End Labeling; Nucleosides; Oligonucleotide Array Sequence Analysis; Receptor, Adenosine A3; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Uridine Triphosphate | 2003 |
Endogenous adenosine modulation of 22Na uptake by rat brain synaptosomes.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Brain; In Vitro Techniques; Rats; Rats, Wistar; Sodium; Sodium Radioisotopes; Synaptosomes; Thioinosine | 2003 |
Regulation of adenosine receptor subtypes during cultivation of human monocytes: role of receptors in preventing lipopolysaccharide-triggered respiratory burst.
Topics: Adenine; Adenosine; Adenosine Deaminase; Base Sequence; Calcium Signaling; Cells, Cultured; Dipyridamole; DNA, Complementary; Humans; In Vitro Techniques; Lipopolysaccharides; Monocytes; Purinergic P1 Receptor Antagonists; Reactive Oxygen Species; Receptors, Purinergic P1; Respiratory Burst; RNA, Messenger | 2004 |
Positive inotropic effect of the inhibition of cyclic GMP-stimulated 3',5'-cyclic nucleotide phosphodiesterase (PDE2) on guinea pig left atria in eu- and hyperthyroidism.
Topics: Adenine; Adenosine; Animals; Cardiotonic Agents; Culture Techniques; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 2; Guinea Pigs; Heart Atria; Hyperthyroidism; Male; Myocardial Contraction; Phosphoric Diester Hydrolases; Thioinosine | 2003 |
Adenosine induces apoptosis in the human gastric cancer cells via an intrinsic pathway relevant to activation of AMP-activated protein kinase.
Topics: Adenine; Adenosine; Adenylate Kinase; Aminoimidazole Carboxamide; Apoptosis; Caspase Inhibitors; Dipyridamole; Drug Interactions; Enzyme Activation; Humans; Membrane Potentials; Mitochondria; Receptors, Purinergic P1; Ribonucleotides; Signal Transduction; Stomach Neoplasms; Tumor Cells, Cultured | 2004 |
Protective effect of adenosine and purine nucleos(t)ides against the death by hydrogen peroxide and glucose deprivation in rat primary astrocytes.
Topics: Adenine; Adenosine; Analysis of Variance; Animals; Animals, Newborn; Astrocytes; Benzimidazoles; Carbocyanines; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Glucose; Hydrogen Peroxide; In Vitro Techniques; L-Lactate Dehydrogenase; Membrane Potentials; Mitochondria; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Rats; Rats, Sprague-Dawley; Theobromine; Thioinosine; Time Factors; Xanthines | 2005 |
Adenosine-dependent induction of glutathione peroxidase 1 in human primary endothelial cells and protection against oxidative stress.
Topics: Adenine; Adenosine; Apoptosis; Cells, Cultured; Endothelial Cells; Enzyme Induction; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Hydrogen Peroxide; Oxidative Stress; Protein Kinase C; Receptors, Purinergic P1; RNA, Messenger; Signal Transduction | 2005 |
Adenosine down-regulates giant depolarizing potentials in the developing rat hippocampus by exerting a negative control on glutamatergic inputs.
Topics: Action Potentials; Adenine; Adenosine; Adenosine Triphosphate; Analgesics; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamic Acid; Hippocampus; In Vitro Techniques; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar; Thioinosine; Xanthines | 2005 |
Adenosine and deoxyadenosine induces apoptosis in oestrogen receptor-positive and -negative human breast cancer cells via the intrinsic pathway.
Topics: Adenine; Adenosine; Apoptosis; Breast Neoplasms; Caspase 3; Caspase 9; Caspases; Cell Line, Tumor; Cell Proliferation; Deoxyadenosines; Dose-Response Relationship, Drug; Humans; Receptors, Estrogen; Thioinosine; Time Factors | 2005 |
Assay of adenosine deaminase isoforms by HPLC.
Topics: Adenine; Adenosine; Adenosine Deaminase; Benzyl Compounds; Chromatography, High Pressure Liquid; Hypoxanthine; Inosine; Isoenzymes | 2006 |
The role of adenosine in chondrocyte death in murine osteoarthritis and in a murine chondrocyte cell line.
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Apoptosis; Cartilage, Articular; Cell Death; Cell Line; Chondrocytes; DNA Fragmentation; Enzyme Inhibitors; Homocysteine; Male; Mice; Mice, Inbred Strains; Osteoarthritis; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; Tubercidin | 2006 |
Moderate hypoxia induces xanthine oxidoreductase activity in arterial endothelial cells.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta; Cattle; Endothelium, Vascular; Enzyme Induction; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Oxygen; Purinergic P1 Receptor Antagonists; Reactive Oxygen Species; Xanthine Oxidase | 2006 |
Fine-tuning modulation of myenteric motoneurons by endogenous adenosine: on the role of secreted adenosine deaminase.
Topics: Acetylcholine; Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase; Analysis of Variance; Animals; Calcium; Cholinergic Antagonists; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Female; In Vitro Techniques; Male; Motor Neurons; Myenteric Plexus; Neural Inhibition; Purinergic Antagonists; Purines; Rats; Rats, Wistar; Tritium | 2006 |
Modulation of ischaemic contracture in mouse hearts: a 'supraphysiological' response to adenosine.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Animals; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Contraction; Myocardial Reperfusion Injury; Receptor, Adenosine A1; Theophylline; Time Factors; Ventricular Function, Left; Ventricular Pressure; Xanthines | 2007 |
Anandamide inhibits endothelin-1 production by human cultured endothelial cells: a new vascular action of this endocannabinoid.
Topics: Adenine; Adenosine; Arachidonic Acids; Cannabinoid Receptor Modulators; Cells, Cultured; Dose-Response Relationship, Drug; Endocannabinoids; Endothelial Cells; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Humans; Nitric Oxide; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Xanthines | 2007 |
Methotrexate and erythro-9-(2-hydroxynon-3-yl) adenine therapy for rat adjuvant arthritis and the effect of methotrexate on in vivo purine metabolism.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Aminoimidazole Carboxamide; Animals; Antirheumatic Agents; Arthritis, Experimental; Biomarkers; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Inhibitors; Methotrexate; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Purines; Rats; Ribonucleosides | 2007 |
Kinetic characterization of adenosine deaminase activity in zebrafish (Danio rerio) brain.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Brain; Cattle; Deamination; Hydrogen-Ion Concentration; Kinetics; Membranes; Metals; Solubility; Substrate Specificity; Temperature; Time Factors; Zebrafish | 2008 |
Adenosine as an endogenous regulating factor of hippocampal sharp waves.
Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Animals; Dizocilpine Maleate; Electric Stimulation; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Membrane Potentials; Mice; Mice, Inbred C57BL; Microelectrodes; Nucleoside Transport Proteins; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Receptor, Adenosine A1; Receptors, N-Methyl-D-Aspartate; Theophylline; Xanthines | 2009 |
A novel mouse model for sudden unexpected death in epilepsy (SUDEP): role of impaired adenosine clearance.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Caffeine; Cause of Death; Death, Sudden; Disease Models, Animal; Enzyme Inhibitors; Epilepsy; Kainic Acid; Mice; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Risk Factors; Seizures; Survival Analysis; Tubercidin | 2010 |
Caspase-4 activation in association with decreased adenosine deaminase activity may be a factor for gastric ulcer.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adult; Aged; Animals; Apoptosis; Caspase 3; Caspases, Initiator; Cell Line, Tumor; Cell Survival; Enzyme Activation; Enzyme Inhibitors; Female; Gastric Mucosa; Humans; Intestinal Mucosa; Male; Middle Aged; Osmolar Concentration; Rats; Stomach; Stomach Ulcer | 2010 |
Rapid determination of adenosine deaminase kinetics using fast-scan cyclic voltammetry.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Caffeine; Cattle; Electric Conductivity; Electrochemistry; Enzyme Assays; Kinetics; Oxidation-Reduction; Pentostatin; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Silver; Time Factors | 2010 |
Adenosine activation of A(2B) receptor(s) is essential for stimulated epithelial ciliary motility and clearance.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Bronchi; Cattle; Cilia; Epithelial Cells; Female; In Vitro Techniques; Isoproterenol; Mice; Mice, Knockout; Movement; Procaterol; Protein Isoforms; Purinergic Agents; Receptors, Purinergic P1; Trachea | 2011 |
Distinctive immunoregulatory effects of adenosine on T cells of older humans.
Topics: Adenine; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adult; Age Factors; Aged; Aged, 80 and over; Antigens, CD; Apyrase; CD28 Antigens; Cells, Cultured; Chemotaxis; Cytokines; Dose-Response Relationship, Drug; Female; Flow Cytometry; Humans; Male; Middle Aged; Phenethylamines; Pyrimidines; T-Lymphocytes; Triazoles; Young Adult | 2012 |
Adenosine-mediated cardiovascular toxicity in amitriptyline-poisoned rats.
Topics: Adenine; Adenosine; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Arterial Pressure; Glucose; Heart Rate; Infusions, Intravenous; Long QT Syndrome; Male; Rats; Rats, Wistar; Thioinosine; Time Factors | 2012 |
Reduced adenosine release from the aged mammalian heart.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adrenergic Antagonists; Aging; Animals; Heart; Hydrolases; Male; Myocardial Contraction; Perfusion; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; Sodium Chloride; Tubercidin | 2012 |
High-intensity swimming exercise reduces neuropathic pain in an animal model of complex regional pain syndrome type I: evidence for a role of the adenosinergic system.
Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine Deaminase Inhibitors; Animals; Caffeine; Exercise Therapy; Hyperalgesia; Male; Mice; Naloxone; Narcotic Antagonists; Neuralgia; Neurons; Reflex Sympathetic Dystrophy; Swimming; Triazines; Triazoles; Xanthines | 2013 |
Modulation of adenosine signaling prevents scopolamine-induced cognitive impairment in zebrafish.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Avoidance Learning; Cognition Disorders; Dipyridamole; Disease Models, Animal; Motor Activity; Muscarinic Antagonists; Nucleoside Transport Proteins; Purinergic P1 Receptor Antagonists; Scopolamine; Signal Transduction; Social Behavior; Zebrafish | 2015 |
Adenosine deaminase inhibitor EHNA exhibits a potent anticancer effect against malignant pleural mesothelioma.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Humans; Mesothelioma; Mice; Mice, Nude; Morpholines; Pleural Neoplasms; Pyrimidines; RNA Interference; RNA, Small Interfering; Transplantation, Heterologous | 2015 |
An adenosine kinase inhibitor, ABT-702, inhibits spinal nociceptive transmission by adenosine release via equilibrative nucleoside transporters in rat.
Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Deaminase; Adenosine Kinase; Analgesics; Animals; Animals, Newborn; Enzyme Inhibitors; Membrane Potentials; Morpholines; Motor Neurons; Neural Pathways; Nociceptive Pain; Pyrimidines; Reflex; Spinal Cord; Tissue Culture Techniques; Xanthines | 2015 |
Inhibition of adenosine metabolism induces changes in post-ictal depression, respiration, and mortality in genetically epilepsy prone rats.
Topics: Adenine; Adenosine; Animals; Blood Gas Analysis; Brugada Syndrome; Disease Models, Animal; Enzyme Inhibitors; Epilepsy; Female; Genetic Predisposition to Disease; Incidence; Male; Oxygen; Rats; Respiration; Respiration Disorders; Seizures; Sex Characteristics; Tubercidin | 2016 |
Inhibition of ecto-5'-nucleotidase and adenosine deaminase is able to reverse long-term behavioural effects of early ethanol exposure in zebrafish (Danio rerio).
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Animals; Antisocial Personality Disorder; Behavior, Animal; Disease Models, Animal; Ethanol; Female; Humans; Pregnancy; Prenatal Exposure Delayed Effects; Social Interaction; Zebrafish | 2020 |