9-(2-hydroxy-3-nonyl)adenine and 1-methyl-3-isobutylxanthine

9-(2-hydroxy-3-nonyl)adenine has been researched along with 1-methyl-3-isobutylxanthine in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19905 (33.33)18.7374
1990's3 (20.00)18.2507
2000's5 (33.33)29.6817
2010's2 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hughes, RA; Manallack, DT; Thompson, PE1
de Esch, IJ; de Graaf, C; Jansen, C; Kanev, GK; Kooistra, AJ; Leurs, R1
Chen, G; Ke, H; Kunz, S; Martinelli, S; Robinson, H; Seebeck, T; Wan, Y; Wang, H1
Dhillon, GS; Honnor, RC; Londos, C1
Church, MK; Hughes, PJ; Vardey, CJ1
Butcher, RW; Clark, RB; Proll, MA1
Dalaker, K; Prydz, H1
Belloni, FL; Gerritsen, ME; Liang, BC1
Monteiro, EC; Monteiro, TC; Silva e Sousa, MA; Vera-Cruz, P1
Maurice, DH; Palmer, D; Tsoi, K1
Côté, M; Gallo-Payet, N; Guillon, G; Payet, MD; Rousseau, E1
Bell, EL; Doyle, DD; Palfrey, HC; Upshaw-Earley, J1
Delbecque, JP; Gautron, F; Manière, G; Vanhems, E1
Andersson, TP; Sköld, HN; Svensson, SP1
Castro, LR; Cooper, DM; Fischmeister, R; Verde, I1

Reviews

1 review(s) available for 9-(2-hydroxy-3-nonyl)adenine and 1-methyl-3-isobutylxanthine

ArticleYear
The next generation of phosphodiesterase inhibitors: structural clues to ligand and substrate selectivity of phosphodiesterases.
    Journal of medicinal chemistry, 2005, May-19, Volume: 48, Issue:10

    Topics: Animals; Binding Sites; Crystallography, X-Ray; Cyclic AMP; Cyclic GMP; Drug Design; Humans; Models, Molecular; Molecular Structure; Phosphodiesterase Inhibitors; Quantitative Structure-Activity Relationship; Xanthines

2005

Other Studies

14 other study(ies) available for 9-(2-hydroxy-3-nonyl)adenine and 1-methyl-3-isobutylxanthine

ArticleYear
PDEStrIAn: A Phosphodiesterase Structure and Ligand Interaction Annotated Database As a Tool for Structure-Based Drug Design.
    Journal of medicinal chemistry, 2016, Aug-11, Volume: 59, Issue:15

    Topics: Databases, Protein; Dose-Response Relationship, Drug; Drug Design; Humans; Ligands; Models, Molecular; Molecular Structure; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Structure-Activity Relationship

2016
Biological and structural characterization of Trypanosoma cruzi phosphodiesterase C and Implications for design of parasite selective inhibitors.
    The Journal of biological chemistry, 2012, Apr-06, Volume: 287, Issue:15

    Topics: Amino Acid Sequence; Bridged Bicyclo Compounds, Heterocyclic; Catalytic Domain; Conserved Sequence; Crystallography, X-Ray; Drug Design; Kinetics; Molecular Sequence Data; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Protein Binding; Protein Structure, Secondary; Protozoan Proteins; Recombinant Proteins; Saccharomyces cerevisiae; Sulfonamides; Surface Properties; Trypanosoma cruzi

2012
cAMP-dependent protein kinase and lipolysis in rat adipocytes. I. Cell preparation, manipulation, and predictability in behavior.
    The Journal of biological chemistry, 1985, Dec-05, Volume: 260, Issue:28

    Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Adenosine Deaminase; Adipose Tissue; Animals; Isoproterenol; Kinetics; Lipolysis; Male; Phenylisopropyladenosine; Protein Kinases; Rats; Rats, Inbred Strains; Seasons; Starvation

1985
Studies on the receptor mediating cyclic AMP-independent enhancement by adenosine of IgE-dependent mediator release from rat mast cells.
    British journal of pharmacology, 1986, Volume: 87, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenine Nucleotides; Adenosine; Animals; Cyclic AMP; Dose-Response Relationship, Drug; Immunoglobulin E; In Vitro Techniques; Male; Mast Cells; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Serotonin; Tachyphylaxis; Theophylline; Time Factors; Tubercidin

1986
A1 and A2 adenosine receptors regulate adenylate cyclase in cultured human lung fibroblasts.
    Molecular and cellular endocrinology, 1986, Volume: 44, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Cell Line; Cyclic AMP; Fibroblasts; Humans; Lung; Receptors, Cell Surface; Receptors, Purinergic; Theophylline; Virulence Factors, Bordetella

1986
Effect of some drugs on thromboplastin activity in mouse trophoblast cells in vitro and in vivo.
    Biochemical pharmacology, 1986, Oct-15, Volume: 35, Issue:20

    Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Animals; Calcium Channel Blockers; Dinoprostone; Felodipine; Female; Gallic Acid; Methylation; Mice; Monensin; Nifedipine; Nitrendipine; Pregnancy; Prostaglandins E; Thromboplastin; Trophoblasts; Tubercidin; Verapamil

1986
Effects of alkylxanthines and calcium antagonists on adenosine uptake by cultured rabbit coronary microvascular endothelium.
    Pharmacology, 1987, Volume: 35, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium Channel Blockers; Cells, Cultured; Coronary Vessels; Dipyridamole; Endothelium; Ethanol; Isoproterenol; Male; Microcirculation; Rabbits; Theophylline; Trifluoperazine; Xanthines

1987
Adenosine increases the cAMP content of the rat carotid body in vitro.
    Advances in experimental medicine and biology, 1996, Volume: 410

    Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenine; Adenosine; Animals; Carotid Body; Cyclic AMP; Male; Nerve Tissue Proteins; Perfusion; Phenethylamines; Rats; Rats, Wistar; Receptors, Purinergic P1; Second Messenger Systems

1996
Synergistic inhibition of vascular smooth muscle cell migration by phosphodiesterase 3 and phosphodiesterase 4 inhibitors.
    Circulation research, 1998, May-04, Volume: 82, Issue:8

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenine; Animals; Aorta; Becaplermin; Cell Movement; Cells, Cultured; Colforsin; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Drug Synergism; Humans; Kinetics; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Quinolones; Rats; Recombinant Proteins

1998
Comparative involvement of cyclic nucleotide phosphodiesterases and adenylyl cyclase on adrenocorticotropin-induced increase of cyclic adenosine monophosphate in rat and human glomerulosa cells.
    Endocrinology, 1999, Volume: 140, Issue:8

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Adenylyl Cyclases; Adolescent; Adrenocorticotropic Hormone; Adult; Animals; Cell Membrane; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Female; Humans; Kinetics; Rats; Rats, Long-Evans; Zona Glomerulosa

1999
Natriuretic peptide receptor-B in adult rat ventricle is predominantly confined to the nonmyocyte population.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; Adenine; Animals; Cells, Cultured; Centrifugation, Density Gradient; Cyclic GMP; Fibroblasts; Fluorescent Antibody Technique; Guanylate Cyclase; Heart Ventricles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth; Myocardium; Natriuretic Peptide, C-Type; Octoxynol; Phosphodiesterase Inhibitors; Phosphorylation; Rats; Receptors, Atrial Natriuretic Factor; Tissue Distribution

2002
Inhibition of ovarian steroidogenesis by cyclic GMP in a fly.
    The Journal of endocrinology, 2003, Volume: 177, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Adenine; Alkaloids; Animals; Brain; Calcium Channels; Carbazoles; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Diptera; Ecdysteroids; Female; Indoles; Organ Culture Techniques; Ovary; Phosphodiesterase Inhibitors; Quinazolines; Signal Transduction; Stimulation, Chemical

2003
Phosphoinositide 3-kinase is involved in Xenopus and Labrus melanophore aggregation.
    Cellular signalling, 2003, Volume: 15, Issue:12

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Androstadienes; Animals; Chromones; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Dose-Response Relationship, Drug; Kinetics; Melanocyte-Stimulating Hormones; Melanophores; Melanosomes; Melatonin; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Norepinephrine; Papaverine; Perciformes; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Phosphoinositide-3 Kinase Inhibitors; Phosphoric Diester Hydrolases; Phosphorylation; Rolipram; Signal Transduction; Wortmannin; Xenopus laevis

2003
Cyclic guanosine monophosphate compartmentation in rat cardiac myocytes.
    Circulation, 2006, May-09, Volume: 113, Issue:18

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-GMP Phosphodiesterases; Adenine; Animals; Atrial Natriuretic Factor; Biological Transport; Cell Compartmentation; Cell Membrane; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 2; Cyclic Nucleotide Phosphodiesterases, Type 5; Cyclic Nucleotide-Gated Cation Channels; Heart Ventricles; Humans; Ion Channel Gating; Ion Channels; Isoenzymes; Male; Myocytes, Cardiac; Natriuretic Peptide, Brain; Nitric Oxide Donors; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperazines; Purines; Rats; Rats, Wistar; Recombinant Fusion Proteins; Sarcolemma; Second Messenger Systems; Sildenafil Citrate; Solubility; Sulfones

2006