Page last updated: 2024-09-02

9-(2,3-dihydroxypropyl)adenine and adenosine

9-(2,3-dihydroxypropyl)adenine has been researched along with adenosine in 6 studies

Compound Research Comparison

Studies
(9-(2,3-dihydroxypropyl)adenine)
Trials
(9-(2,3-dihydroxypropyl)adenine)
Recent Studies (post-2010)
(9-(2,3-dihydroxypropyl)adenine)
Studies
(adenosine)
Trials
(adenosine)
Recent Studies (post-2010) (adenosine)
5601032,5361,0758,930

Protein Interaction Comparison

ProteinTaxonomy9-(2,3-dihydroxypropyl)adenine (IC50)adenosine (IC50)
high affinity choline transporter 1 isoform aHomo sapiens (human)0.3851
Sodium/nucleoside cotransporter 1Homo sapiens (human)5.5
Sodium/nucleoside cotransporter 2Homo sapiens (human)5.5
Adenosine receptor A3Homo sapiens (human)0.0011
Adenosine receptor A1Homo sapiens (human)0.0023
Equilibrative nucleoside transporter 1Homo sapiens (human)63
Solute carrier family 28 member 3Homo sapiens (human)3.3

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carlson, EE; Goswami, M; Wilke, KE1
Cools, M; de Clercq, E2
DeClercq, E; Lin, JC; Pagano, JS1
De Clercq, E; Kitaoka, S; Konno, T1
De Clercq, E; Durbin, RK; Stollar, V1

Other Studies

6 other study(ies) available for 9-(2,3-dihydroxypropyl)adenine and adenosine

ArticleYear
Rational Design of Selective Adenine-Based Scaffolds for Inactivation of Bacterial Histidine Kinases.
    Journal of medicinal chemistry, 2017, 10-12, Volume: 60, Issue:19

    Topics: Adenine; Adenosine Triphosphate; Anti-Bacterial Agents; Aspartic Acid; Bacteria; Drug Design; Histidine Kinase; HSP90 Heat-Shock Proteins; Models, Molecular; Molecular Docking Simulation; Structure-Activity Relationship

2017
Correlation between the antiviral activity of acyclic and carbocyclic adenosine analogues in murine L929 cells and their inhibitory effect on L929 cells S-adenosylhomocysteine hydrolase.
    Biochemical pharmacology, 1989, Apr-01, Volume: 38, Issue:7

    Topics: Adenine; Adenosine; Adenosylhomocysteinase; Animals; Antiviral Agents; Cell Line; Fibroblasts; Hydrolases; Kinetics; Mice; Vaccinia virus; Vesicular stomatitis Indiana virus; Virus Replication

1989
Novel acyclic adenosine analogs inhibit Epstein-Barr virus replication.
    Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:9

    Topics: Adenine; Adenosine; Antimetabolites; Antiviral Agents; Cell Line; Cell Survival; DNA, Viral; Herpesvirus 4, Human; Organophosphonates; Organophosphorus Compounds; Virus Replication

1987
Antiviral potency of adenosine analogues: correlation with inhibition of S-adenosylhomocysteine hydrolase.
    Biochemical and biophysical research communications, 1985, May-31, Volume: 129, Issue:1

    Topics: Adenine; Adenosine; Adenosylhomocysteinase; Antibiotics, Antineoplastic; Antiviral Agents; Hydrolases; Kinetics; Measles virus; Reoviridae; Tubercidin; Vaccinia virus; Vesicular stomatitis Indiana virus; Virus Replication

1985
Comparative efficacy of broad-spectrum antiviral agents as inhibitors of rotavirus replication in vitro.
    Antiviral research, 1986, Volume: 6, Issue:1

    Topics: Adenine; Adenosine; Amides; Antiviral Agents; Cell Line; Cytidine; Dose-Response Relationship, Drug; Pyrazoles; Ribavirin; Ribonucleosides; Ribose; Rotavirus; Tubercidin; Vidarabine; Virus Replication

1986
SVLM21, a mutant of Sindbis virus able to grow in Aedes albopictus cells in the absence of methionine, shows increased sensitivity to S-adenosylhomocysteine hydrolase inhibitors such as neplanocin A.
    Virology, 1988, Volume: 163, Issue:1

    Topics: Adenine; Adenosine; Adenosylhomocysteinase; Aedes; Animals; Antiviral Agents; Cell Line; Genes, Viral; Hydrolases; Methionine; Methyltransferases; Mutation; S-Adenosylmethionine; Sindbis Virus; Tubercidin; Viral Plaque Assay

1988