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9-(2,3-dihydroxypropyl)adenine, (s)-isomer and acyclovir

9-(2,3-dihydroxypropyl)adenine, (s)-isomer has been researched along with acyclovir in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.26)18.7374
1990's2 (10.53)18.2507
2000's11 (57.89)29.6817
2010's5 (26.32)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
De Clercq, E; Herdewijn, P; Hoogmartens, J; Janssen, G; Snoeck, R; Van Aerschot, A; Vandendriessche, F1
Bisagni, E; Boumchita, H; Huel, C; Legraverend, M; Lemaitre, M; Zerial, A1
Bergogne, MC; De Clercq, E; de Rudder, J; Gosselin, G; Imbach, JL1
Carte, N; De Clercq, E; Guillerm, D; Guillerm, G; Lambert, C; Leize, E; Rogniaux, H; Van Dorsselaer, A; Vandenplas-Witkowki, C1
Chiacchio, MA; Corsaro, A; De Clercq, E; Iannazzo, D; Mastino, A; Piperno, A; Rescifina, A; Romeo, G; Romeo, R; Valveri, V1
Balzarini, J; De Clercq, E; Gazivoda, T; Kralj, M; Marjanović, M; Mintas, M; Pavelić, K; Raić-Malić, S1
Alvarez, K; Balzarini, J; Barral, K; Canard, B; Neyts, J; Priet, S; Sire, J1
Andrei, G; Balzarini, J; De Clercq, E; Holý, A; Krecmerová, M; Masojídková, M; Naesens, L; Neyts, J; Pískala, A; Snoeck, R1
Balzarini, J; Clercq, ED; Kralj, M; Makuc, D; Mintas, M; Pavelić, K; Plavec, J; Prekupec, S; Raić-Malić, S; Suman, L1
De Clercq, E; Küçükgüzel, I; Küçükgüzel, SG; Rollas, S; Tatar, E1
Andrei, G; Balzarini, J; De Clercq, E; Gazivoda, T; Kralj, M; Mintas, M; Pavelić, K; Raić-Malić, S; Snoeck, R; Sokcević, M; Suman, L1
Andrei, G; Balzarini, J; De Clercq, E; Holý, A; Krecmerová, M; Masojídková, M; Naesens, L; Neyts, J; Pohl, R; Snoeck, R1
De Clercq, E; Gawin, R; Koszytkowska-Stawińska, M; Naesens, L1
Andrei, G; Bayrak, OF; De Clercq, E; Güniz Küçükgüzel, S; Karakuş, S; Küçükgüzel, I; Pannecouque, C; Sahin, F; Snoeck, R1
Balzarini, J; Głowacka, IE; Piotrowska, DG1
Balzarini, J; Bharatam, PV; Chibale, K; Kaur, H; Little, S; Singh, K1
Balzarini, J; Chibale, K; Kaur, H; Singh, K1
Balzarini, J; Singh, K1
Balzarini, J; De Clercq, E; Karki, SS; Kulkarni, AA; Kumar, S; Veliyath, SK1

Other Studies

19 other study(ies) available for 9-(2,3-dihydroxypropyl)adenine, (s)-isomer and acyclovir

ArticleYear
Synthesis and antiviral activity of acyclic nucleosides with a 3(S),5-dihydroxypentyl or 4(R)-methoxy-3(S),5-dihydroxypentyl side chain.
    Journal of medicinal chemistry, 1992, Apr-17, Volume: 35, Issue:8

    Topics: Antiviral Agents; Microbial Sensitivity Tests; Nucleosides; Simplexvirus; Stereoisomerism; Structure-Activity Relationship

1992
Synthesis of new (+-)-3,5-dihydroxypentyl nucleoside analogues from 1-amino-5-(benzyloxy)pentan-3-ol and their antiviral evaluation.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:9

    Topics: Amino Alcohols; Antiviral Agents; Cell Line; Chemical Phenomena; Chemistry; Humans; Microbial Sensitivity Tests; Nucleosides; Pentanols; Structure-Activity Relationship

1990
Systematic synthesis and biological evaluation of alpha- and beta-D-xylofuranosyl nucleosides of the five naturally occurring bases in nucleic acids and related analogues.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:2

    Topics: Animals; Antiviral Agents; Cell Division; Lethal Dose 50; Mice; Nucleosides; Rabbits

1986
Synthesis, mechanism of action, and antiviral activity of a new series of covalent mechanism-based inhibitors of S-adenosyl-L-homocysteine hydrolase.
    Journal of medicinal chemistry, 2001, Aug-16, Volume: 44, Issue:17

    Topics: Adenosylhomocysteinase; Amino Acid Sequence; Antiviral Agents; Cell Line; Chromatography, Liquid; Enzyme Inhibitors; Humans; Hydrolases; Models, Molecular; Molecular Sequence Data; NAD; Placenta; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Structure-Activity Relationship; Thionucleosides

2001
Synthesis and biological activity of isoxazolidinyl polycyclic aromatic hydrocarbons: potential DNA intercalators.
    Journal of medicinal chemistry, 2006, Jan-26, Volume: 49, Issue:2

    Topics: Animals; Anthracenes; Antineoplastic Agents; Antiviral Agents; Apoptosis; Cell Line, Tumor; Chlorocebus aethiops; DNA; DNA Viruses; Drug Screening Assays, Antitumor; fas Receptor; Humans; Intercalating Agents; Isoxazoles; Phenanthrenes; Polycyclic Aromatic Hydrocarbons; Pyrenes; RNA Viruses; Stereoisomerism; Structure-Activity Relationship; Vero Cells

2006
The novel C-5 aryl, alkenyl, and alkynyl substituted uracil derivatives of L-ascorbic acid: synthesis, cytostatic, and antiviral activity evaluations.
    Bioorganic & medicinal chemistry, 2007, Jan-15, Volume: 15, Issue:2

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Ascorbic Acid; Cell Line, Tumor; Drug Evaluation, Preclinical; Drug Screening Assays, Antitumor; Fibroblasts; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Pyrimidines; Structure-Activity Relationship; Uracil; Viruses

2007
Synthesis, in vitro antiviral evaluation, and stability studies of novel alpha-borano-nucleotide analogues of 9-[2-(phosphonomethoxy)ethyl]adenine and (R)-9-[2-(phosphonomethoxy)propyl]adenine.
    Journal of medicinal chemistry, 2006, Dec-28, Volume: 49, Issue:26

    Topics: Adenine; Animals; Anti-HIV Agents; Antiviral Agents; Boranes; Boron Compounds; Chlorocebus aethiops; DNA Viruses; HIV-1; Humans; In Vitro Techniques; Nucleosides; Organophosphonates; Phosphates; RNA Viruses; Structure-Activity Relationship; Vero Cells; Virus Replication

2006
Antiviral activity of triazine analogues of 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine (cidofovir) and related compounds.
    Journal of medicinal chemistry, 2007, Mar-08, Volume: 50, Issue:5

    Topics: Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Cidofovir; Cytosine; DNA Viruses; Humans; Mice; Organophosphonates; Retroviridae; RNA Viruses; Stereoisomerism; Structure-Activity Relationship; Triazines

2007
Novel C-6 fluorinated acyclic side chain pyrimidine derivatives: synthesis, (1)H and (13)C NMR conformational studies, and antiviral and cytostatic evaluations.
    Journal of medicinal chemistry, 2007, Jun-28, Volume: 50, Issue:13

    Topics: Animals; Antiviral Agents; Cell Line; Cell Line, Tumor; Chlorocebus aethiops; Cytostatic Agents; Drug Screening Assays, Antitumor; Humans; Magnetic Resonance Spectroscopy; Mice; Models, Molecular; Molecular Conformation; Molecular Mimicry; Positron-Emission Tomography; Pyrimidine Nucleosides; Pyrimidines; Structure-Activity Relationship

2007
Synthesis of some novel thiourea derivatives obtained from 5-[(4-aminophenoxy)methyl]-4-alkyl/aryl-2,4-dihydro-3H-1,2,4-triazole-3-thiones and evaluation as antiviral/anti-HIV and anti-tuberculosis agents.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:2

    Topics: Animals; Antitubercular Agents; Antiviral Agents; Cell Line; Drug Evaluation, Preclinical; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Thiourea; Triazoles

2008
Synthesis and antiviral and cytostatic evaluations of the new C-5 substituted pyrimidine and furo[2,3-d]pyrimidine 4',5'-didehydro-L-ascorbic acid derivatives.
    Journal of medicinal chemistry, 2007, Aug-23, Volume: 50, Issue:17

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Ascorbic Acid; Cell Line; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Mice; Pyrimidines; Pyrimidinones; Stereoisomerism; Structure-Activity Relationship

2007
Ester prodrugs of cyclic 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine: synthesis and antiviral activity.
    Journal of medicinal chemistry, 2007, Nov-15, Volume: 50, Issue:23

    Topics: Antiviral Agents; Cell Line; Cytosine; DNA Viruses; Drug Resistance, Viral; Esters; Humans; Magnetic Resonance Spectroscopy; Prodrugs; Retroviridae; RNA Viruses; Stereoisomerism; Structure-Activity Relationship

2007
Synthesis and antiviral evaluation of acyclic azanucleosides developed from sulfanilamide as a lead structure.
    Bioorganic & medicinal chemistry, 2008, Sep-15, Volume: 16, Issue:18

    Topics: Animals; Antiviral Agents; Aza Compounds; Catalysis; Cell Line; DNA Viruses; Drug Resistance, Viral; Humans; Hydrogenation; Nucleosides; Palladium; Pyrimidine Nucleosides; RNA Viruses; Structure-Activity Relationship; Sulfanilamide; Sulfanilamides

2008
Synthesis, antiviral and anticancer activity of some novel thioureas derived from N-(4-nitro-2-phenoxyphenyl)-methanesulfonamide.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:9

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Cell Line; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Microbial Sensitivity Tests; Sulfonamides; Thiourea; Viruses

2009
Design, synthesis, antiviral and cytostatic evaluation of novel isoxazolidine nucleotide analogues with a 1,2,3-triazole linker.
    European journal of medicinal chemistry, 2012, Volume: 47, Issue:1

    Topics: Animals; Antiviral Agents; Cell Line; Cytostatic Agents; Drug Design; Humans; Inhibitory Concentration 50; Mice; Nucleotides; Triazoles; Viruses

2012
2-Aminopyrimidine based 4-aminoquinoline anti-plasmodial agents. Synthesis, biological activity, structure-activity relationship and mode of action studies.
    European journal of medicinal chemistry, 2012, Volume: 52

    Topics: Aminoquinolines; Animals; Antimalarials; Cell Line; DNA; Dogs; Heme; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Plasmodium falciparum; Protoporphyrins; Pyrimidines; Structure-Activity Relationship; Viruses

2012
Synthesis of 4-aminoquinoline-pyrimidine hybrids as potent antimalarials and their mode of action studies.
    European journal of medicinal chemistry, 2013, Volume: 66

    Topics: Antimalarials; Antiviral Agents; Cell Line; Chemistry Techniques, Synthetic; DNA; Heme; Humans; Plasmodium falciparum; Pyrimidines; Structure-Activity Relationship

2013
Regioselective synthesis of 6-substituted-2-amino-5-bromo-4(3H)-pyrimidinones and evaluation of their antiviral activity.
    European journal of medicinal chemistry, 2013, Volume: 67

    Topics: Animals; Antiviral Agents; Cells, Cultured; Chlorocebus aethiops; Dogs; Dose-Response Relationship, Drug; HeLa Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Pyrimidinones; Stereoisomerism; Structure-Activity Relationship; Vero Cells; Viruses

2013
Synthesis and biological evaluation of 2-(5-substituted-1-((diethylamino)methyl)-2-oxoindolin-3-ylidene)-
    Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents, 2013, Volume: 22, Issue:4

    Topics:

2013