8-tert-butyl-6,7-dihydropyrrolo(3,2-e)-5-methylpyrazolo(1,5-a)pyrimidine-3-carbonitrile has been researched along with glyburide in 4 studies
| Studies (8-tert-butyl-6,7-dihydropyrrolo(3,2-e)-5-methylpyrazolo(1,5-a)pyrimidine-3-carbonitrile) | Trials (8-tert-butyl-6,7-dihydropyrrolo(3,2-e)-5-methylpyrazolo(1,5-a)pyrimidine-3-carbonitrile) | Recent Studies (post-2010) (8-tert-butyl-6,7-dihydropyrrolo(3,2-e)-5-methylpyrazolo(1,5-a)pyrimidine-3-carbonitrile) | Studies (glyburide) | Trials (glyburide) | Recent Studies (post-2010) (glyburide) |
|---|---|---|---|---|---|
| 15 | 0 | 0 | 6,554 | 620 | 1,344 |
| Protein | Taxonomy | 8-tert-butyl-6,7-dihydropyrrolo(3,2-e)-5-methylpyrazolo(1,5-a)pyrimidine-3-carbonitrile (IC50) | glyburide (IC50) |
|---|---|---|---|
| ATP-binding cassette sub-family C member 9 | Homo sapiens (human) | 0.22 | |
| Bile salt export pump | Rattus norvegicus (Norway rat) | 5.7 | |
| Bile salt export pump | Homo sapiens (human) | 5.5333 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 1.602 | |
| ATP-binding cassette sub-family C member 8 | Homo sapiens (human) | 0.0043 | |
| ATP-sensitive inward rectifier potassium channel 11 | Homo sapiens (human) | 0.1121 | |
| NACHT, LRR and PYD domains-containing protein 3 | Mus musculus (house mouse) | 10 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 1.8 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kishii, K; Morimoto, T; Nakajima, N; Takayanagi, I; Tsujitani, M | 1 |
| Kishii, K; Morimoto, T; Nakajima, N; Takayanagi, I; Tsujitani, M; Yamazaki, K | 1 |
| Akata, T; Kuriyama, H; Nakashima, M | 1 |
| Daniel, EE; Inazu, M; Zhang, H | 1 |
4 other study(ies) available for 8-tert-butyl-6,7-dihydropyrrolo(3,2-e)-5-methylpyrazolo(1,5-a)pyrimidine-3-carbonitrile and glyburide
| Article | Year |
|---|---|
Endothelium-dependent vasodilation by LP-805, a novel vasodilating agent, on rat thoracic aorta.
Topics: Animals; Aorta, Thoracic; Arginine; Endothelium, Vascular; Glyburide; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Potassium Channels; Pyrazoles; Pyrimidines; Rats; Rats, Inbred Strains; Vasodilation; Vasodilator Agents | 1992 |
Effects of LP-805, a novel vasorelaxant agent, a potassium channel opener, on rat thoracic aorta.
Topics: Animals; Aorta, Thoracic; Calcium; Cytosol; Fura-2; Glyburide; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Potassium; Potassium Channels; Pyrazoles; Pyrimidines; Rats; Rats, Inbred Strains; Rubidium Radioisotopes; Vasodilator Agents | 1992 |
Effects on the rabbit coronary artery of LP-805, a new type of releaser of endothelium-derived relaxing factor and a K+ channel opener.
Topics: Acetylcholine; Action Potentials; Animals; Coronary Vessels; Glyburide; In Vitro Techniques; Indomethacin; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Potassium Channels; Pyrazoles; Pyrimidines; Rabbits; Vasodilator Agents | 1992 |
Properties of the LP-805-induced potassium currents in cultured bovine pulmonary artery endothelial cells.
Topics: 4-Aminopyridine; Animals; Cattle; Cells, Cultured; Endothelium, Vascular; Glyburide; Membrane Potentials; Potassium Channels; Pulmonary Artery; Pyrazoles; Pyrimidines; Quaternary Ammonium Compounds; Tetraethylammonium; Tetraethylammonium Compounds; Vasodilator Agents | 1994 |