Page last updated: 2024-09-05

8-tert-butyl-6,7-dihydropyrrolo(3,2-e)-5-methylpyrazolo(1,5-a)pyrimidine-3-carbonitrile and arginine

8-tert-butyl-6,7-dihydropyrrolo(3,2-e)-5-methylpyrazolo(1,5-a)pyrimidine-3-carbonitrile has been researched along with arginine in 3 studies

Compound Research Comparison

Studies
(8-tert-butyl-6,7-dihydropyrrolo(3,2-e)-5-methylpyrazolo(1,5-a)pyrimidine-3-carbonitrile)
Trials
(8-tert-butyl-6,7-dihydropyrrolo(3,2-e)-5-methylpyrazolo(1,5-a)pyrimidine-3-carbonitrile)
Recent Studies (post-2010)
(8-tert-butyl-6,7-dihydropyrrolo(3,2-e)-5-methylpyrazolo(1,5-a)pyrimidine-3-carbonitrile)
Studies
(arginine)
Trials
(arginine)
Recent Studies (post-2010) (arginine)
150046,3881,68811,176

Protein Interaction Comparison

ProteinTaxonomy8-tert-butyl-6,7-dihydropyrrolo(3,2-e)-5-methylpyrazolo(1,5-a)pyrimidine-3-carbonitrile (IC50)arginine (IC50)
Cationic amino acid transporter 3Homo sapiens (human)283

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kishii, K; Morimoto, T; Nakajima, N; Takayanagi, I; Tsujitani, M1
Hirano, K; Kanaide, H; Ushio-Fukai, M1
Inazu, M; Tujitani, M1

Other Studies

3 other study(ies) available for 8-tert-butyl-6,7-dihydropyrrolo(3,2-e)-5-methylpyrazolo(1,5-a)pyrimidine-3-carbonitrile and arginine

ArticleYear
Endothelium-dependent vasodilation by LP-805, a novel vasodilating agent, on rat thoracic aorta.
    General pharmacology, 1992, Volume: 23, Issue:3

    Topics: Animals; Aorta, Thoracic; Arginine; Endothelium, Vascular; Glyburide; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Potassium Channels; Pyrazoles; Pyrimidines; Rats; Rats, Inbred Strains; Vasodilation; Vasodilator Agents

1992
The effects of a novel vasodilator, LP-805, on cytosolic Ca2+ concentrations and on tension in rabbit isolated femoral arteries.
    British journal of pharmacology, 1994, Volume: 113, Issue:4

    Topics: Animals; Arginine; Benzopyrans; Calcium; Cromakalim; Cytosol; Endothelium, Vascular; Femoral Artery; Fura-2; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Norepinephrine; Potassium; Pyrazoles; Pyrimidines; Pyrroles; Rabbits; Vasodilator Agents

1994
Effect of LP-805, a releaser of endothelium-derived nitric oxide, on systemic vasodilatation in vivo.
    Naunyn-Schmiedeberg's archives of pharmacology, 1993, Volume: 348, Issue:2

    Topics: Acetylcholine; Animals; Arginine; Blood Pressure; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypotension; Indomethacin; Injections, Intravenous; Male; Nitric Oxide; Nitroarginine; Pyrazoles; Pyrimidines; Rats; Rats, Wistar; Vasodilation; Vasodilator Agents

1993